2IVU: Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD6474

PDB ID: 2IVUDownload
MMDB ID: 41233
PDB Deposition Date: 2006/6/16
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2IVU: dimeric; determined by author and by software (PQS)
Molecular Components in 2IVU
Label Count Molecule
Proteins (2 molecules)
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET Precursor
(Gene symbol: RET)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
FORMIC ACIDFORMIC ACID
2
2
VandetanibVandetanib
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303