2IBW: Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function

PDB ID: 2IBWDownload
MMDB ID: 45049
PDB Deposition Date: 2006/9/12
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2IBW: tetrameric; determined by author and by software (PISA)
Molecular Components in 2IBW
Label Count Molecule
Proteins (4 molecules)
4
Acetyl-coa Acetyltransferase
(Gene symbol: ACAT1)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
CHLORIDE IONCHLORIDE ION
2
4
POTASSIUM IONPOTASSIUM ION
3
4
COENZYME ACOENZYME A
4
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303