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2BR1:
Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity
PDB ID:
2BR1
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MMDB ID:
33397
PDB Deposition Date:
2005/4/29
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2BR1: monomeric; determined by author and by software (PQS)
Molecular Components in 2BR1
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase Chk1
(Gene symbol:
CHEK1
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL
2
2
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303