2BEL: Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone

PDB ID: 2BELDownload
MMDB ID: 86793
PDB Deposition Date: 2004/11/25
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 2BEL: dimeric; determined by author and by software (PQS)
Molecular Components in 2BEL
Label Count Molecule
Proteins (2 molecules)
2
Corticosteroid 11-beta-dehydrogenase Isozyme 1
(Gene symbol: HSD11B1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
CARBENOXOLONECARBENOXOLONE
3
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303