1WCI: Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch

PDB ID: 1WCIDownload
MMDB ID: 37428
PDB Deposition Date: 2004/11/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.84  Å
Source Organism:
Similar Structures:
Biological Unit for 1WCI: tetrameric; determined by author and by software (PQS)
Molecular Components in 1WCI
Label Count Molecule
Proteins (4 molecules)
2
2-oxoisovalerate Dehydrogenase Alpha Subunit
(Gene symbol: BCKDHA)
Molecule annotation
2
2-oxoisovalerate Dehydrogenase Beta Subunit
(Gene symbol: BCKDHB)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
CHLORIDE IONCHLORIDE ION
2
2
C2-1-HYDROXY-3-METHYL-BUTYL-THIAMINC2-1-HYDROXY-3-METHYL-BUTYL-THIAMIN
3
4
POTASSIUM IONPOTASSIUM ION
4
2
MANGANESE (II) IONMANGANESE (II) ION
5
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303