1UNH: Structural mechanism for the inhibition of CDK5-p25 by roscovitine, aloisine and indirubin

PDB ID: 1UNHDownload
MMDB ID: 51667
PDB Deposition Date: 2003/9/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 1UNH: dimeric; determined by author and by software (PISA)
Molecular Components in 1UNH
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 5
(Gene symbol: CDK5)
Molecule annotation
1
Cyclin-dependent Kinase 5 Activator 1
(Gene symbol: CDK5R1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME(Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303