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Conserved domains on  [gi|403531863|ref|YP_006666182|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Nimbochromis linni]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 562.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 241 ALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 403531863 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 562.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 241 ALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 403531863 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 3.52e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.99  E-value: 3.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSS---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLAFKL-----NDSTNINTLATSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 403531863  235 KAPALTALMPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-299 4.20e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 84.78  E-value: 4.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   8 TLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTqataaatllfASVTNAWL------ 80
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLL----------GALSSGFLlygisl 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 ----TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQ 144
Cdd:COG1007  176 lygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLR 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 145 L--------QPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTF 212
Cdd:COG1007  256 LlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 213 STF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALL 287
Cdd:COG1007  336 GAFavillLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|..
gi 403531863 288 SLYFYLRLSYAM 299
Cdd:COG1007  416 SAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 15-299 8.74e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 71.90  E-value: 8.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPL 93
Cdd:TIGR01770 113 LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   94 PSTMIT------------LALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS--------STLL 153
Cdd:TIGR01770 193 SNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseawQIFL 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  154 IILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTY-FIMTFSTFLAF---------KLNDS 223
Cdd:TIGR01770 273 AIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYiFIYALMSLGAFgvlsllrsyKDEWI 352

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 403531863  224 TNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 353 EYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 562.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 241 ALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 403531863 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 2.78e-133

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 383.50  E-value: 2.78e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 240 TALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLpST 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 403531863 320 QLTYPLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 6.80e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 341.80  E-value: 6.80e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 240 TALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 403531863 320 QLTYpLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 1.11e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 338.74  E-value: 1.11e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 240 TALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 403531863 320 QLTYPLATSTAMTICLLPLTPAISAL 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 1.04e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 305.74  E-value: 1.04e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS-STLLIILGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALnSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 240 TALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*...
gi 403531863 320 qLTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00200 321 -SNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 2.21e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 243.68  E-value: 2.21e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL-QPSSSTLLIILGLT 159
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 240 TALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|.
gi 403531863 320 QLTYPLATSTAMTICLLPLTP 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLL 341
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-307 7.86e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 172.32  E-value: 7.86e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   1 MNPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGqweiqqITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILglTS 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIII--LS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00160 154 AIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIK 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 403531863 241 ALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNN 307
Cdd:MTH00160 234 FLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-318 3.40e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 154.66  E-value: 3.40e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  10 LFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIqqi 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  90 thplpSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSS--TLLIILGLTSTLIGGWG 167
Cdd:MTH00144  87 -----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLatSWAKAPALTALMPLIL 247
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL--GSLKPSYKTGLSIISL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403531863 248 LSLGG-LPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPS 318
Cdd:MTH00144 240 LLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 13-329 7.23e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 146.08  E-value: 7.23e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  13 MGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASvtnawlTGQWEIQQITHP 92
Cdd:MTH00011  15 MTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  93 LPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLII-LGLTSTLIGGWGGLNQ 171
Cdd:MTH00011  89 ITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQ 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 172 TQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALTALMPLILLSLG 251
Cdd:MTH00011 169 TQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLG 248

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403531863 252 GLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTlTISPNNLTGSTPWRLPSTQLTYPLATST 329
Cdd:MTH00011 249 GLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM-YLSPTFSSLKSAPYEPKTKILISMCTLS 325
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-297 3.88e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 141.35  E-value: 3.88e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   9 LLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLlfasvtnawLTGQWEIQQ 88
Cdd:MTH00197   3 FLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALL---------LMGGSLSFS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  89 --ITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFaLILQLQPSSSTLLIILGLTSTLIGGW 166
Cdd:MTH00197  74 nlYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL-LILAFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALTALMPLI 246
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 403531863 247 LLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSY 297
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-266 8.62e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 94.71  E-value: 8.62e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHP-RAVEATTKYF-------------LTQATAAATLLFASVTNAWL 80
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFvlgalssglflfgCALLCGTTGGLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLiILGLTS 160
Cdd:MTH00196  84 NSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILL-IGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFIMT---FSTFLAFKLNDSTNINTLATSw 233
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSicvFSIILALNVYKNLIIEFSGLS- 241

                        250       260       270
                 ....*....|....*....|....*....|...
gi 403531863 234 AKAPALTALMPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00196 242 RRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 3.52e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.99  E-value: 3.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSS---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLAFKL-----NDSTNINTLATSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 403531863  235 KAPALTALMPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 14-266 2.26e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.54  E-value: 2.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  14 GLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHP 92
Cdd:MTH00199 107 ALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINSI 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  93 LPS----TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLtSTLIGGWGG 168
Cdd:MTH00199 187 LTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SIIYGAIGA 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 169 LNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFIMT---FSTFLAFKLNDSTNINTLATSwAKAPALTA 241
Cdd:MTH00199 266 LNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSicsFSIILSLKLTKGLIVEVSGLS-RKNPVIAL 344

                        250       260
                 ....*....|....*....|....*
gi 403531863 242 LMPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00199 345 TLALTFLSIAGIPPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-299 4.20e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 84.78  E-value: 4.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   8 TLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTqataaatllfASVTNAWL------ 80
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLL----------GALSSGFLlygisl 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 ----TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQ 144
Cdd:COG1007  176 lygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLR 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 145 L--------QPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTF 212
Cdd:COG1007  256 LlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 213 STF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALL 287
Cdd:COG1007  336 GAFavillLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|..
gi 403531863 288 SLYFYLRLSYAM 299
Cdd:COG1007  416 SAYYYLRVVKAM 427
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-299 5.24e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 78.71  E-value: 5.24e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   4 YILATL-LFGMGLgttitFASS-HWLLAWMGLEMNTLAIIPLMAQH-HHPRAVEATTKYFLTqataaatllfASVTNAWL 80
Cdd:PRK05777 106 YLLVLFaLLGMMV-----MVSAnDLLTLFLGLELLSLPLYALAALRrDRRRSLEAAIKYFVL----------GALASGFL 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 ----------TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAP 138
Cdd:PRK05777 171 lygmsllygaTGSLSFAGIAKALADGsgnsllllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAA 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 139 FALIL--------QLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLT 206
Cdd:PRK05777 251 FAVLLrllvvafgGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLaagtAEGYSAVLFYLLA 330

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 207 YFIMTFSTF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLA 281
Cdd:PRK05777 331 YLFMTLGAFgvislLRRKGGEAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIG 410

                        330
                 ....*....|....*...
gi 403531863 282 ALSALLSLYFYLRLSYAM 299
Cdd:PRK05777 411 VLNSAIGAFYYLRVIKLM 428
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 15-299 8.74e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 71.90  E-value: 8.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPL 93
Cdd:TIGR01770 113 LGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   94 PSTMIT------------LALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS--------STLL 153
Cdd:TIGR01770 193 SNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseawQIFL 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  154 IILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTY-FIMTFSTFLAF---------KLNDS 223
Cdd:TIGR01770 273 AIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYiFIYALMSLGAFgvlsllrsyKDEWI 352

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 403531863  224 TNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 353 EYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 1.77e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 58.42  E-value: 1.77e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 403531863  290 YFYLRLSYAMTLTISPNNLTGSTPWRLPSTQLTYPLATSTAMTICLLPLTP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-217 6.92e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 63.34  E-value: 6.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   9 LLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAV---------EATTKYFLTQATAAATLLFASVTNAW 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  80 LTGQ--------------WEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL 145
Cdd:MTH00198 273 FTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403531863 146 QPSSStLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLA 217
Cdd:MTH00198 353 VITSK-LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTYLVSALA 423
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-273 3.84e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 60.55  E-value: 3.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   2 NPYILATLLFGMGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQATAAATLLFASVTNAWLT 81
Cdd:COG0651  105 RGRRFYPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAT 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  82 GQWEIQQITHPLPS----------TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGL--ILSTWQKLAP 138
Cdd:COG0651  185 GTLNMADLAARLAEldpglllaafALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 139 FALILQLQPssstLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI--MTFST-- 214
Cdd:COG0651  265 ADPALFLGT----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhALAKAll 340

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403531863 215 FLA----FKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQG 273
Cdd:COG0651  341 FLAagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAG 403
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 100-191 1.50e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.72  E-value: 1.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  100 LALALKIGLAPLHAWLPEV-LQGLDLTTGLILSTWQKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWGGLNQ 171
Cdd:TIGR01972 211 IAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLrfnLPLFPDASlyfaPVLAALGVIAIIYGALIALAQ 290

                          90       100
                  ....*....|....*....|
gi 403531863  172 TQLRKILAYSSIAHLGWMIL 191
Cdd:TIGR01972 291 TDIKRLIAYSSISHMGFVLL 310
ndhB CHL00049
NADH dehydrogenase subunit 2
 98-295 6.20e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 53.85  E-value: 6.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSSST----LLIILGLTSTLIGGWGGL 169
Cdd:CHL00049 220 ITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNewhlLLEILAILSMILGNLIAI 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 170 NQTQLRKILAYSSIAHLGW-MILVLQFSPSITLLTLLTYFIM-------TFSTFLAFKLNDST-NINTLATSWAKAPALT 240
Cdd:CHL00049 300 TQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFyifmnlgTFACIVLFGLRTGTdNIRDYAGLYTKDPFLA 379

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 403531863 241 ALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRL 295
Cdd:CHL00049 380 LSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-193 1.31e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 50.15  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  78 AWLTGQWEIQQI----THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQG-----------LDLTTGLILstwqk 135
Cdd:COG1009  186 GAIAGTLNFSELlaaaPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDAMEGptpvsallhaaTMVKAGVYL----- 260

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 403531863 136 LAPFALILQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:COG1009  261 LARLSPLFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 8-193 3.04e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 48.77  E-value: 3.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863   8 TLLFGMGLgttiTFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYF----------LTQATAAATLLFASVTN 77
Cdd:PRK06458 116 LFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIiicsvgvafaLFGTILVYANAATVMGD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  78 AWLTGQW-EIQQITHPLPSTMITLALAL-------KIGLAPLHAWLPE-----------VLQGLDLTTGLILSTWQKLAP 138
Cdd:PRK06458 192 GEMAILWtELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYILI 271

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 403531863 139 FALILQLQPSssTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK06458 272 DAAIGSDFPG--RLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFAL 324
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 100-191 3.41e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 48.54  E-value: 3.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 100 LALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWG 167
Cdd:COG1008  217 IAFAVKVPMFPFHTWLPDAHVeaptaGSVLLAGVLL----KMGGYGLLrfaLPLFPEASayfaPLLAALGVIGIIYGALV 292

                         90       100
                 ....*....|....*....|....
gi 403531863 168 GLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:COG1008  293 ALAQTDLKRLIAYSSVSHMGFVLL 316
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
96-202 2.32e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 45.86  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSSSTL----LIILGLTSTLIGGWG 167
Cdd:PRK07363 209 TGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLvapgLAIIGTISVIYGALS 288

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 403531863 168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLL 202
Cdd:PRK07363 289 AIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-193 2.71e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 46.07  E-value: 2.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  81 TGQWEIQQI-THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTL 152
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFADV 263

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 403531863 153 ------LIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK12644 264 pvwrptVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 75-191 3.24e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.58  E-value: 3.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  75 VTNAWLTGQWEIQQI-THPLPSTMITL-------ALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFAL 141
Cdd:PRK05846 186 VVYYNATGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAHVqaptaGSVLLAGILL----KMGAYGL 261

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 403531863 142 I---LQLQPSSS----TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK05846 262 LrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTL 318
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-299 4.11e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 45.35  E-value: 4.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  92 PLPSTMITLALAL-----KIGLAPLHAWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFALILqlq 146
Cdd:PRK12667 218 PPLALGVALALALwaftiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAAL--- 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 147 pssSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI-------MTFSTFLAF- 218
Cdd:PRK12667 295 ---SPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksLLFLASGVFi 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 219 KLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYA 298
Cdd:PRK12667 372 HAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451


                 .
gi 403531863 299 M 299
Cdd:PRK12667 452 L 452
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-335 5.31e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 44.87  E-value: 5.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI----------LQLQPSSSTLLIILGLTSTLIGG 165
Cdd:PRK08375 207 FVLLALALKAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGS 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFS----PSITLLTLLTYFIMTFSTFLA----FKLNDSTNINTLATSWAKAP 237
Cdd:PRK08375 287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLtplaLAAGLLHLLHHALMKGALFLAagaiEVTYGTRRLSELSGLGRRMP 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 238 ALTALMPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNltGSTPWRLP 317
Cdd:PRK08375 367 LTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPG--SEAPKQEA 444

                        250
                 ....*....|....*...
gi 403531863 318 STQLTYPLATSTAMTICL 335
Cdd:PRK08375 445 PLGMLAPSLALALLSLLL 462
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
102-262 6.12e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 44.66  E-value: 6.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 102 LALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSSST----LLIILGLTSTLIGGWGGLNQTQ 173
Cdd:PRK02504 220 IAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLvtafPSFDEqwklLFTALAILSMVLGNVVALAQTS 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 174 LRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLA---FKLNDSTN-INTLATSWAKAPALTALMPL 245
Cdd:PRK02504 300 MKRMLAYSSIGQAGFVMIGLvagtEAGYASMVFYLLAYLFMNLGAFACvilFSLRTGTDqISDYAGLYQKDPLLTLGLSL 379

                        170
                 ....*....|....*..
gi 403531863 246 ILLSLGGLPPLTGFMPK 262
Cdd:PRK02504 380 CLLSLGGIPPLAGFFGK 396
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-231 6.34e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 44.09  E-value: 6.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTSTLIGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 403531863 177 ILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLAT 231
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWET 193
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-207 1.60e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 43.53  E-value: 1.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 111 LHAWLPEVLQGLDLTTGLI-LSTWQKLAPFALI-----LQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplFEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90       100
                 ....*....|....*....|....
gi 403531863 185 HLGWMILVLQFSP-SITLLTLLTY 207
Cdd:MTH00020 309 QLGYMVVACGLSHySISLFHLMNH 332
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 100-191 3.81e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 42.33  E-value: 3.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 100 LALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSS----STLLIILGLTSTLIGGWGGLNQ 171
Cdd:PRK12561 193 IAFGVKLPIFPLHTWLPDAHGEASAPVSMILAgVLLKMGGYALIrfnVQMLPDAhvyfAPALAILGVVNIIYGALNAFAQ 272

                         90       100
                 ....*....|....*....|
gi 403531863 172 TQLRKILAYSSIAHLGWMIL 191
Cdd:PRK12561 273 DNVKRRLAYSSVSHMGFVLL 292
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-266 6.86e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 41.26  E-value: 6.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI-----------LQLQPSSSTLLIILGLTSTLIGG 165
Cdd:PRK12662 215 IMVGLFIKAALFPFHKWLIQAYSEAPSFISVFFSgTSTKVMIYLIIrivydvfkanfVFTTLPFNNVFMILAALAIVFGS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI---------MTFSTFLAFKLnDSTNINTLATSWAKA 236
Cdd:PRK12662 295 VLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVnhsivksalFMVSGSISYHF-GTTKLEDCLNLWKSM 373

                        170       180       190
                 ....*....|....*....|....*....|
gi 403531863 237 PALTALMPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:PRK12662 374 PKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 7.44e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 41.55  E-value: 7.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSS------TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFEqfpavmTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 403531863 184 AHLGWMIL 191
Cdd:PRK07376 325 SQLGYMVM 332
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 96-191 7.87e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.28  E-value: 7.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  96 TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGLilstWQKLAPFALILQLQ--PSSSTLLIILGLTSTL 162
Cdd:PRK08676 210 LFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQSGaaEQFSNVLIGLGIFSIA 285

                         90       100
                 ....*....|....*....|....*....
gi 403531863 163 IGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK08676 286 VAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK12650 PRK12650
DUF4040 family protein;
110-190 8.50e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.18  E-value: 8.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 110 PLHAWLPEVLQGLD-----------LTTGLILstwqkLAPFALILQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKIL 178
Cdd:PRK12650 226 PFHFWLPEAMAAITpvsaflhaaavVKAGIYL-----LLRFSPVFHDVAVWNWLLIIVGMITALMGAVFAVQKTDLKKLT 300

                         90
                 ....*....|..
gi 403531863 179 AYSSIAHLGWMI 190
Cdd:PRK12650 301 AYSTVSQLGWIV 312
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 8.82e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 41.10  E-value: 8.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQP----SSSTLLII--LGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekAPLTLLIItiFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 403531863 185 HLGWMILVL 193
Cdd:MTH00032 324 QLGYMVLII 332
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
98-191 1.33e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.45  E-value: 1.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  98 ITLALALKIGLAPLHAWLPE-----------VLQG--LDLTT--------GLILSTWQKLAPFalilqlqpssstlLIIL 156
Cdd:PRK06473 211 ILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATW 277

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 403531863 157 GLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK06473 278 AVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-200 1.50e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.42  E-value: 1.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 100 LALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWG 167
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGYGFIrfsWPLLPEASeyfsPLIQTLSLLAIIYGSLT 289

                         90       100       110
                 ....*....|....*....|....*....|...
gi 403531863 168 GLNQTQLRKILAYSSIAHLGWMILVLqFSPSIT 200
Cdd:MTH00217 290 TCRQVDLKRIIAYSSVAHMGLVTLGI-FSHTIQ 321
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 1.64e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.29  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  98 ITLALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALILQLQP-------SSSTLLIILGLTSTLIGG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPilplgaqNLAPAVIAMGIVGIVYGS 311

                         90       100
                 ....*....|....*....|....*...
gi 403531863 166 WGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:MTH00226 312 FATCRQIDVKRLVAYSSVAHMGLVSITL 339
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 96-193 3.44e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 38.98  E-value: 3.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTW-QKLAPFAL-----ILQLQPSSST---LLIILGLTSTLIGGW 166
Cdd:PRK08377 210 ALLIFGLAVEAELFPLNAWAPDAYQAAPHPITVMFSAFvVKAGLYAMarilyLMQNANGWSSvlkLVIIMATLTVFFAEL 289

                         90       100
                 ....*....|....*....|....*..
gi 403531863 167 GGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK08377 290 SALRQKNVKRMIAYSSIGQVGMIALAL 316
NDH_I_L TIGR01974
proton-translocating NADH-quinone oxidoreductase, chain L; This model describes the 12th ...
 110-193 6.96e-03

proton-translocating NADH-quinone oxidoreductase, chain L; This model describes the 12th (based on E. coli) structural gene, L, of bacterial NADH dehydrogenase I, as well as chain 5 of the corresponding mitochondrial complex I and subunit 5 (or F) of the chloroplast NAD(P)H-plastoquinone dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273905 [Multi-domain]  Cd Length: 609  Bit Score: 38.42  E-value: 6.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863  110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALI------LQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSI 183
Cdd:TIGR01974 231 PLHTWLPDAMEGPTPVSALIHAATMVTAGVYLVartsplFELSPTALYLVTIIGAITALFAATVALVQNDIKRILAYSTM 310

                          90
                  ....*....|
gi 403531863  184 AHLGWMILVL 193
Cdd:TIGR01974 311 SQLGYMFLAL 320
ND5 MTH00210
NADH dehydrogenase subunit 5; Provisional
 111-192 7.12e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177253 [Multi-domain]  Cd Length: 616  Bit Score: 38.07  E-value: 7.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL------QLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00210 230 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLIIrsgplfEGSPLALTIVTILGALTAFFAATVGVVQNDLKKVIAYSTCS 309


                 ....*...
gi 403531863 185 HLGWMILV 192
Cdd:MTH00210 310 QLGYMVMV 317
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-203 7.72e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 38.12  E-value: 7.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 403531863 100 LALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALI---LQLQPSSST----LLIILGLTSTLIGGWG 167
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLrfsWPLFPAASEyfapLIVMLSVIAVIYGSLT 292

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 403531863 168 GLNQTQLRKILAYSSIAHLGWMILVLqFSPSITLLT 203
Cdd:MTH00204 293 TCRQVDFKRLIAYSSVAHMGLVPLGL-FTHTIEGLV 327
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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