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Conserved domains on  [gi|386800932|ref|YP_006303581|]
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LAGLIDADG endonuclease (mitochondrion) [Aspergillus nidulans FGSC A4]

Protein Classification

LAGLIDADG family homing endonuclease( domain architecture ID 10469810)

LAGLIDADG family homing endonuclease belongs to a large family of homing endonucleases that each contain one or two copies of a motif that resembles the consensus sequence LAGLIDADG and is directly involved in the DNA cutting process

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
44-141 8.46e-16

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 71.90  E-value: 8.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932   44 LAGLIEGDGTIIVPNTLR-SPKGKLNYPSIQIVFHLKDLPLALMIQKELGFGSLSRKKGVNAYILTINN-KEGILFVISL 121
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSkSYKGYRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|.
gi 386800932  122 LNG-NMRTPKINSLYKLIDFY 141
Cdd:pfam00961  81 FDKyPLLTSKYLDYLDFKKIY 101
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
163-268 6.85e-12

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 61.11  E-value: 6.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932  163 LSGFIEADGSFQVRSTLSGKY--PKFECKLEISQRQtdhkgfSNQEFLNKIADFFHTEVKETRLNRSTPEYRVrTTNLQG 240
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgYRVRLRFQISLHS------KDENLLEKIKNYLGIGSISKRKNDNTVIYII-SNSKKS 73

                          90       100
                  ....*....|....*....|....*...
gi 386800932  241 NNQAKSYFIKYPLFGTKYLDSIDWMKVV 268
Cdd:pfam00961  74 LNIIIPYFDKYPLLTSKYLDYLDFKKIY 101
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
44-141 8.46e-16

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 71.90  E-value: 8.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932   44 LAGLIEGDGTIIVPNTLR-SPKGKLNYPSIQIVFHLKDLPLALMIQKELGFGSLSRKKGVNAYILTINN-KEGILFVISL 121
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSkSYKGYRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|.
gi 386800932  122 LNG-NMRTPKINSLYKLIDFY 141
Cdd:pfam00961  81 FDKyPLLTSKYLDYLDFKKIY 101
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
163-268 6.85e-12

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 61.11  E-value: 6.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932  163 LSGFIEADGSFQVRSTLSGKY--PKFECKLEISQRQtdhkgfSNQEFLNKIADFFHTEVKETRLNRSTPEYRVrTTNLQG 240
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgYRVRLRFQISLHS------KDENLLEKIKNYLGIGSISKRKNDNTVIYII-SNSKKS 73

                          90       100
                  ....*....|....*....|....*...
gi 386800932  241 NNQAKSYFIKYPLFGTKYLDSIDWMKVV 268
Cdd:pfam00961  74 LNIIIPYFDKYPLLTSKYLDYLDFKKIY 101
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
44-141 8.46e-16

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 71.90  E-value: 8.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932   44 LAGLIEGDGTIIVPNTLR-SPKGKLNYPSIQIVFHLKDLPLALMIQKELGFGSLSRKKGVNAYILTINN-KEGILFVISL 121
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSkSYKGYRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|.
gi 386800932  122 LNG-NMRTPKINSLYKLIDFY 141
Cdd:pfam00961  81 FDKyPLLTSKYLDYLDFKKIY 101
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
163-268 6.85e-12

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 61.11  E-value: 6.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386800932  163 LSGFIEADGSFQVRSTLSGKY--PKFECKLEISQRQtdhkgfSNQEFLNKIADFFHTEVKETRLNRSTPEYRVrTTNLQG 240
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgYRVRLRFQISLHS------KDENLLEKIKNYLGIGSISKRKNDNTVIYII-SNSKKS 73

                          90       100
                  ....*....|....*....|....*...
gi 386800932  241 NNQAKSYFIKYPLFGTKYLDSIDWMKVV 268
Cdd:pfam00961  74 LNIIIPYFDKYPLLTSKYLDYLDFKKIY 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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