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Conserved domains on  [gi|237641919|ref|YP_002122303|]
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NADH dehydrogenase subunit 4 (mitochondrion) [Opisthorchis felineus]

Protein Classification

NADH dehydrogenase subunit 4( domain architecture ID 11475885)

NADH dehydrogenase subunit 4 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 43-425 1.68e-123

NADH dehydrogenase subunit 4; Provisional


:

Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 364.24  E-value: 1.68e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  43 FGGVFCFDAISLYLVLLSALLCISLL-FWWGGINFVSGVMIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESP 121
Cdd:MTH00062  37 FNGLFIFDSLSFYLILLVLFLGLYSQvMFYNLLSGVSRFFLFLSLIFSILCFCVNNSLLFWFFYELSIIPLLYLLFSESP 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 122 YSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEAS 201
Cdd:MTH00062 117 YSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFSDWGSDDSVSLIVYYVLSFMFITKVPLFPFHTWLPIVHAEAS 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 202 SPVSVCLSGYIMKLGILGVCRFCSAILPDLVFssGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGG 281
Cdd:MTH00062 197 SPVSIFLSGYIMKLGLLGVYRFCGFIFSGSFL--GYLFLCCLFSVFFLITACSELDGKRWLAFLSLSHILVPVLGLFVGD 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 282 YLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEA 361
Cdd:MTH00062 275 WSSINLSFFYCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSS 354

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237641919 362 FSkNVMFGAVLFMYLFLGGLVPLFLMGTVLSRHWDVSYSGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00062 355 FG-VLVYLLFWCFYLFFGGLVPLILLGHLLIRSESYESINVSNYSYLFFLIFLVFWCYLGFLVL 417
 
Name Accession Description Interval E-value
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 43-425 1.68e-123

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 364.24  E-value: 1.68e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  43 FGGVFCFDAISLYLVLLSALLCISLL-FWWGGINFVSGVMIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESP 121
Cdd:MTH00062  37 FNGLFIFDSLSFYLILLVLFLGLYSQvMFYNLLSGVSRFFLFLSLIFSILCFCVNNSLLFWFFYELSIIPLLYLLFSESP 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 122 YSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEAS 201
Cdd:MTH00062 117 YSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFSDWGSDDSVSLIVYYVLSFMFITKVPLFPFHTWLPIVHAEAS 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 202 SPVSVCLSGYIMKLGILGVCRFCSAILPDLVFssGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGG 281
Cdd:MTH00062 197 SPVSIFLSGYIMKLGLLGVYRFCGFIFSGSFL--GYLFLCCLFSVFFLITACSELDGKRWLAFLSLSHILVPVLGLFVGD 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 282 YLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEA 361
Cdd:MTH00062 275 WSSINLSFFYCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSS 354

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237641919 362 FSkNVMFGAVLFMYLFLGGLVPLFLMGTVLSRHWDVSYSGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00062 355 FG-VLVYLLFWCFYLFFGGLVPLILLGHLLIRSESYESINVSNYSYLFFLIFLVFWCYLGFLVL 417
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 74-371 5.38e-20

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 91.92  E-value: 5.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919   74 INFVSGVMIGlslifsllCYCCINALWFWVFYEM*IVPLLVLLVLESPySERYVASWYFLGYVIFTSLPMLLCFFYLS-L 152
Cdd:TIGR01972 112 LLLLEAGVIG--------VFLALDLFLFYVFWEAMLIPMYLLIGVWGG-PNRIYAAMKFFLYTLAGSLLMLLAILGLYfL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  153 SAGSFDLRVWGPMN---GVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP 229
Cdd:TIGR01972 183 GGGTFDLLELLNLPlpfGVQTWLFLAFFIAFAVKVPLFPLHTWLPDAHVEAPTAGSVILAGVLLKMGTYGFLRFNLPLFP 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  230 D--LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCH---ILIAAGCLCVGGyLLGGVsfVYCLGHGISAGLTFL 304
Cdd:TIGR01972 263 DasLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHmgfVLLGIFSFNELG-ISGAV--FQMISHGLITAALFL 339

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237641919  305 FLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAV 371
Cdd:TIGR01972 340 LVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFL 406
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 76-318 8.38e-18

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 85.13  E-value: 8.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  76 FVSGVMIGlslifsllCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLgYVIFTSLPMLLCFFYLSLSAG 155
Cdd:COG1008  119 LLEAGMIG--------VFLALDLFLFYVFWELMLIPMYFLIGIWGGERRIYAAIKFFL-YTLAGSLLMLVAILALYFLAG 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 156 --SFDLRVWGPMN---GVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPD 230
Cdd:COG1008  190 alTFDIAELAAAPlplTAQLLLFLAFFIAFAVKVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLKMGGYGLLRFALPLFPE 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 231 --LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCH---ILIAAGCLCVGGyLLGGVsfVYCLGHGISAGLTFLF 305
Cdd:COG1008  270 asAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHmgfVLLGIFALNPLG-LQGAV--LQMVSHGLITAALFLL 346

                        250
                 ....*....|...
gi 237641919 306 LWLSYEISGTRNL 318
Cdd:COG1008  347 VGVLYDRTHTRDI 359
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 97-372 1.34e-16

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 79.66  E-value: 1.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919   97 NALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLR------VWGPMNGVGL 170
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDelskalTGGLNSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  171 VIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGYVLLCIFLSFLFFF 250
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  251 SAS-RELDGKRWLAFLSLCHI---LIAAGCLCVGGYLLggvSFVYCLGHGISAGLTFL-FLWLSYEISGTRNLFLLKSAV 325
Cdd:pfam00361 163 LAAlVQTDIKRLLAYSSISHMgymLIALGAGTIYGIQA---AIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDYGGLA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 237641919  326 SGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVL 372
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
 
Name Accession Description Interval E-value
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 43-425 1.68e-123

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 364.24  E-value: 1.68e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  43 FGGVFCFDAISLYLVLLSALLCISLL-FWWGGINFVSGVMIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESP 121
Cdd:MTH00062  37 FNGLFIFDSLSFYLILLVLFLGLYSQvMFYNLLSGVSRFFLFLSLIFSILCFCVNNSLLFWFFYELSIIPLLYLLFSESP 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 122 YSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEAS 201
Cdd:MTH00062 117 YSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFSDWGSDDSVSLIVYYVLSFMFITKVPLFPFHTWLPIVHAEAS 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 202 SPVSVCLSGYIMKLGILGVCRFCSAILPDLVFssGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGG 281
Cdd:MTH00062 197 SPVSIFLSGYIMKLGLLGVYRFCGFIFSGSFL--GYLFLCCLFSVFFLITACSELDGKRWLAFLSLSHILVPVLGLFVGD 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 282 YLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEA 361
Cdd:MTH00062 275 WSSINLSFFYCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSS 354

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237641919 362 FSkNVMFGAVLFMYLFLGGLVPLFLMGTVLSRHWDVSYSGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00062 355 FG-VLVYLLFWCFYLFFGGLVPLILLGHLLIRSESYESINVSNYSYLFFLIFLVFWCYLGFLVL 417
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 74-371 5.38e-20

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 91.92  E-value: 5.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919   74 INFVSGVMIGlslifsllCYCCINALWFWVFYEM*IVPLLVLLVLESPySERYVASWYFLGYVIFTSLPMLLCFFYLS-L 152
Cdd:TIGR01972 112 LLLLEAGVIG--------VFLALDLFLFYVFWEAMLIPMYLLIGVWGG-PNRIYAAMKFFLYTLAGSLLMLLAILGLYfL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  153 SAGSFDLRVWGPMN---GVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP 229
Cdd:TIGR01972 183 GGGTFDLLELLNLPlpfGVQTWLFLAFFIAFAVKVPLFPLHTWLPDAHVEAPTAGSVILAGVLLKMGTYGFLRFNLPLFP 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  230 D--LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCH---ILIAAGCLCVGGyLLGGVsfVYCLGHGISAGLTFL 304
Cdd:TIGR01972 263 DasLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHmgfVLLGIFSFNELG-ISGAV--FQMISHGLITAALFL 339

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237641919  305 FLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAV 371
Cdd:TIGR01972 340 LVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFL 406
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 46-316 5.15e-18

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 86.13  E-value: 5.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  46 VFCFDAISLYLVLLSALLC-ISLLFWWGGINFVSGVMIGLSLIFSLLCYCCINAL---WFWVFYEM*IVPLLVLLVLESP 121
Cdd:MTH00226  97 VFAVDGISIYFIILTGFIVpCSILISWHSVKYLTKSFLICMLILEFLLYAVFSVLdifMFYILFEGVLIPMYLILGIWGS 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 122 YSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPMNGV-------GLVIGVVLSVMfiTKIPLFPFHVWLP 194
Cdd:MTH00226 177 REEKMQAAYYFFFYTLIGSVLMLLCLFSLYNIHGTTDYLTLASCSHVvseqtqkWIFLGIFLAMA--VKIPIFPFHIWLP 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 195 IVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP--DLVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILI 272
Cdd:MTH00226 255 KAHVEAPVAGSVLLAGILLKLGGYGLVRLSWPILPlgAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGL 334

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 237641919 273 AAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTR 316
Cdd:MTH00226 335 VSITLVTHDIIGLTGSIFIMLAHGIVSSLLFILVTILYDRHHTR 378
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 73-389 7.22e-18

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 85.38  E-value: 7.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  73 GINFVSGVMIGLSLIFSLLcycciNALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSL 152
Cdd:MTH00206  94 YITLLIVLQLFLILFFSSS-----NLLLFYILFEASLIPTLLLITRWGNQKERLNAGYYFLFYTLIGSLPLLIALLFLQN 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 153 SAGSFDLRVWG---PMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP 229
Cdd:MTH00206 169 SLGSLSLYILYfskLTTWNNNLWWLACILAFLVKLPLYGVHLWLPKAHVEAPVAGSMVLAGVLLKLGGYGMMRIILILGP 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 230 DLVFSSG-YVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWL 308
Cdd:MTH00206 249 STKLSSYfFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALLLMIAHGLVSSALFCLANL 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 309 SYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLFMYLFLGGLVPLFLMG 388
Cdd:MTH00206 329 LYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLPLLGLGFLFTAIYSLYMFV 408


                 .
gi 237641919 389 T 389
Cdd:MTH00206 409 M 409
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 76-318 8.38e-18

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 85.13  E-value: 8.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  76 FVSGVMIGlslifsllCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLgYVIFTSLPMLLCFFYLSLSAG 155
Cdd:COG1008  119 LLEAGMIG--------VFLALDLFLFYVFWELMLIPMYFLIGIWGGERRIYAAIKFFL-YTLAGSLLMLVAILALYFLAG 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 156 --SFDLRVWGPMN---GVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPD 230
Cdd:COG1008  190 alTFDIAELAAAPlplTAQLLLFLAFFIAFAVKVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLKMGGYGLLRFALPLFPE 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 231 --LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCH---ILIAAGCLCVGGyLLGGVsfVYCLGHGISAGLTFLF 305
Cdd:COG1008  270 asAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHmgfVLLGIFALNPLG-LQGAV--LQMVSHGLITAALFLL 346

                        250
                 ....*....|...
gi 237641919 306 LWLSYEISGTRNL 318
Cdd:COG1008  347 VGVLYDRTHTRDI 359
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 81-425 2.17e-17

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 83.66  E-value: 2.17e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  81 MIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLR 160
Cdd:MTH00163  92 LILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLLVGIFYLYNNSGSLSFF 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 161 VWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP-DLVFSSGYVL 239
Cdd:MTH00163 172 LLNFFGSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGLLRVMSFFSKlGLKFNYIWIS 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 240 LCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNLF 319
Cdd:MTH00163 252 ISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLLMMIGHGLCSSGLFCLANIIYERLGSRSLL 331

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 320 LLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLFMYLFLGGLVPLFLMgtVLSRHwDVSY 399
Cdd:MTH00163 332 INKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMIFLMLLSFFSAAYSLYLY--SYSQH-GKYY 408

                        330       340
                 ....*....|....*....|....*.
gi 237641919 400 SGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00163 409 SGLYSCSSGKVREYLLLFLHWLPLNL 434
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 97-372 1.34e-16

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 79.66  E-value: 1.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919   97 NALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLR------VWGPMNGVGL 170
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDelskalTGGLNSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  171 VIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGYVLLCIFLSFLFFF 250
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  251 SAS-RELDGKRWLAFLSLCHI---LIAAGCLCVGGYLLggvSFVYCLGHGISAGLTFL-FLWLSYEISGTRNLFLLKSAV 325
Cdd:pfam00361 163 LAAlVQTDIKRLLAYSSISHMgymLIALGAGTIYGIQA---AIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDYGGLA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 237641919  326 SGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVL 372
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
97-354 1.55e-15

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 78.20  E-value: 1.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  97 NALWFWVFYEM*IVPLLVLLVLESPySERYVASWYFLGYVIFTSLPMLLCFFYLSLSAG--SFDLRVWGPMN---GVGLV 171
Cdd:PRK06473 128 DLLLFFLFYELELIPLYLLIAIWGG-QRRGYAATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLRSHTlplSTQLL 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 172 IGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPD--LVFSSGYVLLCIFLSFLFF 249
Cdd:PRK06473 207 LLAPILVGFGIKIPLVPFHTWLPDAHVEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEawVYLAPWLATWAVVSVLYGA 286

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 250 FSASRELDGKRWLAFLSLCH---ILIAAGC---LCVGGYLLGGVSfvyclgHGISAGLTFLFLWLSYEISGTRNLFLLKS 323
Cdd:PRK06473 287 SCAIAQKDMKKMVAYSSIGHmgyILLAAAAatpLSILAAVFQMIS------HGLISALLFLLVGVVYKKTGSRDVDVLRG 360

                        250       260       270
                 ....*....|....*....|....*....|....
gi 237641919 324 AVSGSLFLRVLACLCLCTVCS---LPGTVQFFCE 354
Cdd:PRK06473 361 LLNPERGLPITGSLMILGVMAsagIPGMVGFIAE 394
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 75-425 4.42e-15

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 76.42  E-value: 4.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  75 NFVSGVMIGLSLIfSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSA 154
Cdd:MTH00150  55 SSFSLLVLLLCLI-LVLAFSVSSLLMFYFFFEASLIPTLLLILGWGYQPERLQAGMYMMLYTVGASLPLLLVILWMSSSY 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 155 GSFD---LRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAI-LPD 230
Cdd:MTH00150 134 GSSFmllISSLRKLLSSMGLWGLLVFLAFLVKLPMYPFHLWLPKAHVEAPVAGSMILAGILLKLGGYGILRMMMVFsLSS 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 231 LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHI-LIAAGCLcvGGYLLGGVS-FVYCLGHGISAGLTFLFLWL 308
Cdd:MTH00150 214 SSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMsLVLAGVL--SNTSWGWVGaLIMMVSHGFCSSGLFCLANY 291

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 309 SYEISGTRNLFLLKsavsGSLFLRVLACLCLCTVCSL----PGTVQFFCEVQFLGEAFSKNVMFGAVLFMYLFLGGLVPL 384
Cdd:MTH00150 292 TYEKVHSRSLFLSK----GMLMLYPSLSLWWFLFCIInmaaPPSLNLLSEIMIFPSLISYSPWFFVPLGLMVFLSGLYSL 367

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 237641919 385 FLMGTVlsRHWDVSYSGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00150 368 YLYTSI--QHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLL 406
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 76-371 7.87e-15

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 76.01  E-value: 7.87e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  76 FVSGVMIGLslifsllcYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLgYVIFTSLPMLLCFFYL----S 151
Cdd:PRK05846 119 WLEGGVIGV--------FAALDLLLFYVFFEAMLIPMYFLIGVWGGKNRIYAATKFFL-YTLLGSLLMLVAIIYLvvvyY 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 152 LSAGSFDLRVWGPMN---GVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAIL 228
Cdd:PRK05846 190 NATGTFDIADLLNLPlppGVQYWLFLAFFIAFAVKMPMFPLHTWLPDAHVQAPTAGSVLLAGILLKMGAYGLLRFSLPLF 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 229 PDL--VFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCH---ILIAAGCLCVGGyLLGGVsfVYCLGHGISAGLTF 303
Cdd:PRK05846 270 PDAshEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHmgfVTLGIFAGNQLG-IQGAI--FQMISHGLSSAALF 346

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237641919 304 LFLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAV 371
Cdd:PRK05846 347 LLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVIAFI 414
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 81-386 1.15e-14

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 75.55  E-value: 1.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  81 MIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCF---FYLSLSAGSF 157
Cdd:MTH00014  95 NILILNLILLLTFSASNLLMFYIFFEASLIPTLFLILGWGYQPERLQASFYLMIYTVTASLPLLMSIlliFYTNNSLSML 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 158 DLRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGY 237
Cdd:MTH00014 175 MSSMEPPSIYLMNLWWLITILAFMVKMPLYTVHLWLPKAHVEAPVAGSMILAGILLKLGGYGLLRMSSLFMHINKSLSAP 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 238 VL-LCIFLSFLFFFSASRELDGKRWLAFLSLCHI-LIAAGCLCVGGYLLGGvSFVYCLGHGISAGLTFLFLWLSYEISGT 315
Cdd:MTH00014 255 FSsISLVGAVITSLICIRQPDLKSLIAYSSVGHMgLMTAGIMSNTSWGWQG-ALAMMIAHGLCSSALFALANMTYETTHT 333

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 237641919 316 RNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLFMYLFLGGLVPLFL 386
Cdd:MTH00014 334 RSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAILLAITSFLAAAYSLFL 404
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 80-386 2.31e-14

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 74.63  E-value: 2.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  80 VMIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDL 159
Cdd:MTH00205  92 VSVIMLLLILILSFSVDNLLLFYITFEASLIPTLILILGWGYQPERLQASMYMMMYTLCASLPLLIGLFFLNSLNFSLSM 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 160 RVWGPMNGVGLVIGVVLSVM---FITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLV-FSS 235
Cdd:MTH00205 172 FFNFPLNFSDFYLFLYWIFLmlaFLVKLPMYFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGLIRITSMLYKLNSnFSE 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 236 GYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGT 315
Cdd:MTH00205 252 LFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAIIMMVAHGLCSSGMFALANVNYERTNS 331

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 237641919 316 RNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLFMYLFLGGLVPLFL 386
Cdd:MTH00205 332 RSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGIPLSLISFLSGAYSLYL 402
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 97-393 1.41e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 72.10  E-value: 1.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  97 NALWFWVFYEM*IVPLLVLLVLESpYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPM-----NGVGLV 171
Cdd:COG0651  128 DLFNLFVFFEVMLLASYGLVALGG-TKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARlaeldPGLLLA 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 172 IGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSS-GYVLLCIFLS--FLF 248
Cdd:COG0651  207 AFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLTKVGVYAILRVLTLLFGADPALFlGTLLLVLGLLtmLVG 286

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 249 FFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNLFLLKSAVSGS 328
Cdd:COG0651  287 ALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRM 366

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 237641919 329 LFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLfmyLFLGGLVPLFLMGTVLSR 393
Cdd:COG0651  367 PLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAV---LLLSSLLTLAYFVRIFGR 428
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 64-425 7.35e-13

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 69.55  E-value: 7.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  64 CISLLFWWGGINFVSGVMIGLSLIFSLLCYCCI------NALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVI 137
Cdd:MTH00094  44 LIFMMVFILGLVLLSEKNFNLLILSNLLILICLlffvssNMLMLYMFFELSMFPILIMILGYGSQIEKINSSYYLLFYAA 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 138 FTSLPMLLCFF--YLSLSAGSFDLRVWGPMNgvglvigVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKL 215
Cdd:MTH00094 124 FFSFPFLFVYLknFFFFSLCYFDFFLSWEMF-------FILSLSFMMKFPVYFLHLWLPKAHVEAPTTASMLLAGLLLKL 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 216 GILGVCRFCSAILpdLVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGH 295
Cdd:MTH00094 197 GTAGFLRILGSLN--FVYNNFWIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMMLAH 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 296 GISAGLTFLFLWLSYEISGTRNLFLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFFCEVQFLGEAFSKNVMFGAVLFMY 375
Cdd:MTH00094 275 GYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIFFY 354

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 237641919 376 LFLGGLVPLFLMgtvLSRHWDVSYSGRYVFSGIISMGFLILWSFVLFLIV 425
Cdd:MTH00094 355 FLVSFYYSLFLI---VSSFMGKKFSNFNNFNVGLSLPLVFMMFNMFWLSL 401
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 96-270 2.47e-12

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 68.55  E-value: 2.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  96 INALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFD----LRVWGPMN-GVGL 170
Cdd:MTH00204 132 LDLLLFYILFEGILIPMFLLIGIWGSREEKVRASYYFFFYTFAGSVFMLLGIFQLYSITGTTDyqilLNIKLPLSiQKWL 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 171 VIGVVLSvmFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP--DLVFSSGYVLLCIFLSFLF 248
Cdd:MTH00204 212 LVGFFLS--LAVKIPQIPFHIWLPQAHVEAPVAGSVILAGILLKLGGYGFLRFSWPLFPaaSEYFAPLIVMLSVIAVIYG 289

                        170       180
                 ....*....|....*....|..
gi 237641919 249 FFSASRELDGKRWLAFLSLCHI 270
Cdd:MTH00204 290 SLTTCRQVDFKRLIAYSSVAHM 311
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 65-316 1.09e-11

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 66.23  E-value: 1.09e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  65 ISLLFWWGGINF-VSGVMIGLSLIFSLL--CYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSL 141
Cdd:MTH00217  95 ICILISWNSIKFlIKEFLLCLLVIEILLmgVFTILDLVGFYILFEGILIPMFLIIGIWGSREEKVQASYYFFFYTFIGSV 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 142 PMLLCFFYLSLSAGSFDLRVWGPMNGVG-----LVIGVVLSvmFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLG 216
Cdd:MTH00217 175 FMLLGIFTLYSYAGTTDYQALCCLKIEKelqyfIFLGFFLS--LAIKIPKIPFHIWLPQAHVEAPVAGSVILAGVLLKLG 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 217 ILGVCRFCSAILPDLV--FSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHIliaaGCLCVGGY---LLGGVSFVY 291
Cdd:MTH00217 253 GYGFIRFSWPLLPEASeyFSPLIQTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHM----GLVTLGIFshtIQGLVAAIF 328

                        250       260
                 ....*....|....*....|....*.
gi 237641919 292 C-LGHGISAGLTFLFLWLSYEISGTR 316
Cdd:MTH00217 329 LmLAHGLVSSALFIAVTFLYERHHTR 354
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
97-321 1.87e-11

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 65.50  E-value: 1.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  97 NALWFWVFYEM*IVPLLVLLVLESPYSERYvASWYFLGYVIFTSLPMLLCFFYLSLSAGS--FDLRVWGPMN---GVGLV 171
Cdd:PRK07363 128 NLLLFFLFYELELIPFYLLIAIWGGEKRGY-ASIKFLIYTAVSGLLVLAAFLGIVWLSGStsFDYDAISTQNlslNTQLI 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 172 IGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDL--VFSSGYVLLCIFLSFLFF 249
Cdd:PRK07363 207 LLTGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGGVLAKLGTYGLLRFGLQLFPQTwsLVAPGLAIIGTISVIYGA 286

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 237641919 250 FSASRELDGKRWLAFLSLCH---ILIAAGClCVGGYLLGGVSFVycLGHGISAGLTFLFLWLSYEISGTRNLFLL 321
Cdd:PRK07363 287 LSAIAQKDIKRMVAYSSIGHmgyILVAAAA-GTQLSLLGAVAQM--ISHGLILALLFHLVGIVERKVGTRDLDVL 358
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 99-304 1.08e-10

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 63.13  E-value: 1.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  99 LWFWVFYEM*IVPLLVLLVLESPYSERYVASwYFLGYVIFTSLPMLLCFFYLSLSAGSF-----DLRVWGPMNGVGLVIG 173
Cdd:PRK12561 110 LLFFLMWELELVPVYLLISIWGGQKRLYAAT-KFILYTALASIFILVAGLALALSGDTFtfdlaELGAKSYPLALELLLY 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 174 VVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPD--LVFSSGYVLLCIFLSFLFFFS 251
Cdd:PRK12561 189 AGFLIAFGVKLPIFPLHTWLPDAHGEASAPVSMILAGVLLKMGGYALIRFNVQMLPDahVYFAPALAILGVVNIIYGALN 268

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237641919 252 ASRELDGKRWLAFLSLCHIliaagclcvgGYLLGGVSFVYCLG----------HG-ISAGLTFL 304
Cdd:PRK12561 269 AFAQDNVKRRLAYSSVSHM----------GFVLLGIAAFTDLGisgamlqmisHGlIAAALFFL 322
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 80-320 1.84e-08

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 56.14  E-value: 1.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  80 VMIGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCF-----FYLSLSA 154
Cdd:MTH00044  98 SLIIIILTALIITFSSLELILFYIAFETTLIPTLILITRWGAQKERIQAGLYFLFYTLFGSLPLLISLiaiysSSSSLSI 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 155 GSFDLRVWGPMNGVGLVIGVVLSVM-FITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSA-ILPDLV 232
Cdd:MTH00044 178 PLSELNWLTSLSSNSSSIWWIFCILaFLVKMPIYGFHLWLPKAHVEAPVAGSMILAAILLKLGGYGLIRLINLfSLPSAN 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 233 FSSGYVLL-CIFLSFLFFFSASRELDGKRWLAFLSLCHI-LIAAGCLCVGGYLLGGvSFVYCLGHGISAGLTFLFLWLSY 310
Cdd:MTH00044 258 NISFILIVfCCWGALITSIICLRQTDLKALIAYSSVGHMsLVAAGIFSGTNWGING-ALILMIAHGLVSSALFCLANILY 336

                        250
                 ....*....|
gi 237641919 311 EISGTRNLFL 320
Cdd:MTH00044 337 ERSGTRTLSI 346
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 72-272 2.74e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 55.89  E-value: 2.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  72 GGINFVSGVMiGLSLIFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLS 151
Cdd:PRK08667 108 ERANLLSALT-ALFILSMLGVVASANTFSFLFFWEIMALSSFFLVMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLF 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 152 LSAGSFDLRVWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAIL-PD 230
Cdd:PRK08667 187 IQTGSFELSPLGASAGILSLVFLLLFLGFGIKAGIIPFHKWLPYAHPASPSNVSALMSGVMLKVAVYGLVRFLMDVLsPE 266

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 237641919 231 LVFSSGYVLLCIFLSFLFFFSASRELDGKRWLAFLSLCHILI 272
Cdd:PRK08667 267 LWWGVLILLAGSISALLGVIYALKEHDLKGLLAYSSIENIGI 308
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 99-304 7.72e-08

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 54.33  E-value: 7.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  99 LWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLgYVIFTSLPMLLCFFYLSLSAG--SFDLRVWGPMN---GVGLVIG 173
Cdd:PRK02546 138 LLFFLAWELELIPVYLLLAIWGGKKRQYAATKFIL-YTAGSSLFILLAALAMAFYGDtpTFDMTALAAKDfglGFQLLCY 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 174 VVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPD--LVFSSGYVLLCIFLSFLFFFS 251
Cdd:PRK02546 217 AGLLIAYGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALLRMNAGMLPDahAQFAPLLIVLGVVNIIYAALT 296

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 252 ASRELDGKRWLAFLSLCH---ILIAAGC---LCVGGYLLGGVSfvyclgHG-ISAGLTFL 304
Cdd:PRK02546 297 SFAQRNLKRKIAYSSISHmgfVLIGIGSftdLGTSGAMLQMIS------HGlIGASLFFL 350
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 87-320 1.20e-07

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 53.81  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  87 IFSLLCYCCINALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWG--- 163
Cdd:MTH00127 105 IFLILAFGATEIIMFYVMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLLQNSTGTLSMLTLQysq 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 164 --PMNGVGLVIGVVLSVM-FITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILP-DLVFSSGYVL 239
Cdd:MTH00127 185 plQLSSWADKLWWAGCLLaFLVKMPLYGVHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRMMVMLDPlTKELSYPFII 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 240 LCIFLSFLFFFSASRELDGKRWLAFLSLCHI-LIAAGCLCVGGYLLGGvSFVYCLGHGISAGLTFLFLWLSYEISGTRNL 318
Cdd:MTH00127 265 LALWGIIMTGSICLRQTDLKSLIAYSSVSHMgLVAGGILIQTPWGFTG-ALILMIAHGLTSSALFCLANTNYERTHSRTM 343


                 ..
gi 237641919 319 FL 320
Cdd:MTH00127 344 LL 345
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 97-240 4.35e-07

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 52.20  E-value: 4.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919  97 NALWFWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVWGPMNGVGLVIGVVL 176
Cdd:PRK06521 134 DAFSFLVAWETMSLSSWFLVIANHREAEIRRAGFLYLLMAHAGALAILLAFGLLARESGSYDFAAMRAAHLSPFWASLVF 213

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237641919 177 SVMFI---TKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGYVLL 240
Cdd:PRK06521 214 LLALFgfgAKAGLVPLHVWLPRAHPAAPSHVSALMSGVMLKVAIYGILRVVFDLLGAPGWWWGVLVL 280
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 168-318 1.11e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 50.74  E-value: 1.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 168 VGLVIGVVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGY--------VL 239
Cdd:PRK12667 221 ALGVALALALWAFTIKAAIFPNHFWLPDAHPAAPSPVSAMLSGLVVNVGAYAIIRFLYTIFGISPSLIDFraalspilII 300

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 237641919 240 LCIFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNL 318
Cdd:PRK12667 301 LGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDI 379
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 101-274 1.35e-06

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 50.30  E-value: 1.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 101 FWVFYEM*IVPLLVLLVLESPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVW------GPMNGVGLVIGV 174
Cdd:MTH00068 118 FYIFFEATLIPTLIIITRWGNQEERLNAGTYFLFYTLAGSLPLLIALLILQNSLGSLSLILLelmspmQLMTYTNKIWWL 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 175 VLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRFcSAILPDLVFSSGY--VLLCIFLSFLFFFSA 252
Cdd:MTH00068 198 ACLLAFMVKMPLYGLHLWLPKAHVEAPIAGSMILAAVLLKLGGYGILRI-SILLTPLSKELSYpfIILALWGVLMTSLIC 276

                        170       180
                 ....*....|....*....|....
gi 237641919 253 SRELDGKRWLAFLSLCH--ILIAA 274
Cdd:MTH00068 277 LRQTDLKSLIAYSSVSHmgLVIAA 300
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 174-283 2.30e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 46.46  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 174 VVLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRF----CSAILPDLVfSSGYVLLCIFLSFLFF 249
Cdd:PRK06458 218 VFLLIGFGTKVGLFPMHAWLPDAHSEAPSPVSALLSGVLLNVALYAVLRYyiliDAAIGSDFP-GRLLLIFGLLSVLVAA 296

                         90       100       110
                 ....*....|....*....|....*....|....
gi 237641919 250 FSASRELDGKRWLAFLSLCHILIAAGCLCVGGYL 283
Cdd:PRK06458 297 FFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPL 330
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 180-305 2.62e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.10  E-value: 2.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 180 FITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCRfCSAILPDL-----VFSSGYVLLCIflsflffFSASR 254
Cdd:PRK07234 194 LLVKGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVR-CALDVPGLdlivrIFGVGTALLGV-------LFALL 265

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 237641919 255 ELDGKRWLAFLSLCHIliaagclcvgGYLLGG--VSFVYCLGHGISAGLTFLF 305
Cdd:PRK07234 266 EKDLKRMLAFSTISQL----------GFILAAplVGGLYALAHGLVKSTLFLC 308
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 101-219 2.93e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 46.14  E-value: 2.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 101 FWVFYEM*IVPLLVLLVLESPYSERYvASWYFLGYVIFTSLpMLLCFFYLSLSAGSFDLR------VWGPMNGVGLVIGV 174
Cdd:PRK08668 123 LYIFWEIMTFSSFMMVPMGKKESRKA-SLKYFVLSAIGAYA-MLYAIFLIYAKTGTFDFAdisqglINDTSTGFALIVFL 200

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 237641919 175 VLSVMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILG 219
Cdd:PRK08668 201 FLLAFGVAKAGIFPLHVWAPDAYSEAPQSFSAVLSGQLSKLGAYG 245
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 124-222 2.00e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 43.26  E-value: 2.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 124 ERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGS---FDLRVWGPM---NGVGLVIGVVLSVMFITKIPLFPFHVWLPIVH 197
Cdd:MTH00124 141 ERLSAGTYFLFYTLISSLPLLIAILYLHNQTGTlslPMLQLTHPTltnSWTNLLLWLACLMAFMVKMPLYGLHLWLPKAH 220

                         90       100
                 ....*....|....*....|....*
gi 237641919 198 AEASSPVSVCLSGYIMKLGILGVCR 222
Cdd:MTH00124 221 VEAPIAGSMVLAAILLKLGGYGIIR 245
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 101-318 2.39e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 43.33  E-value: 2.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 101 FWVFYEM*IVPLLVLLVLeSPYSERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFDLRVW---GPMNGVGLVIGVVLS 177
Cdd:PRK08375 131 LFVFLEIMSLSSYALVAM-GGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLagaLAENPTVVTAFGFVL 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 178 VMFITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCR-----FCSAILPDLVFSSGYVLLCIFLSFLFFFSA 252
Cdd:PRK08375 210 LALALKAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYALIRiyftvFGGDFRFALGLGWLLAVLALLSMLVGSLAA 289

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 237641919 253 SRELDGKRWLAFLSLCHIliaagclcvgGYLLGGVSF----------VYCLGHGISAGLTFLFLWLSYEISGTRNL 318
Cdd:PRK08375 290 LGQDDVKRVLAYSTVSQM----------GYILLGLALltplalaaglLHLLHHALMKGALFLAAGAIEVTYGTRRL 355
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 123-222 3.49e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 42.57  E-value: 3.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 123 SERYVASWYFLGYVIFTSLPMLLCFFYLSLSAGSFD---LRVWG-PMNGVGLVIGVVLSVM--FITKIPLFPFHVWLPIV 196
Cdd:MTH00110 140 TERLNAGLYFLFYTLVGSLPLLVALLYIQNNLGSLNfllLQLWAqPLPNSWSNNLLWLACMmaFMVKMPLYGLHLWLPKA 219

                         90       100
                 ....*....|....*....|....*.
gi 237641919 197 HAEASSPVSVCLSGYIMKLGILGVCR 222
Cdd:MTH00110 220 HVEAPIAGSMVLAAILLKLGGYGMMR 245
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 180-222 4.71e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.43  E-value: 4.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 237641919 180 FITKIPLFPFHVWLPIVHAEASSPVSVCLSGYIMKLGILGVCR 222
Cdd:PRK08676 216 FLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILR 258
PRK12650 PRK12650
DUF4040 family protein;
161-409 3.49e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 39.64  E-value: 3.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 161 VWGPMNGVGLVIGVVLSVMFITKIPLFPFHVWLPIVHAeASSPVSVCLSGYIM-KLGILGVCRFcSAILPDLVFSSGYVL 239
Cdd:PRK12650 199 VWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMA-AITPVSAFLHAAAVvKAGIYLLLRF-SPVFHDVAVWNWLLI 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 240 LC-IFLSFLFFFSASRELDGKRWLAFLSLCHILIAAGCLCVGGYLLGGVSFVYCLGHGISAGLTFLFLWLSYEISGTRNL 318
Cdd:PRK12650 277 IVgMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDI 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237641919 319 FLLKSAVSGSLFLRVLACLCLCTVCSLPGTVQFfcevqflgeaFSKNVMFGAvlFMYLFLGG-LVPLFLMGTVLSRHWDV 397
Cdd:PRK12650 357 RRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGF----------VSKEGMLTA--FLEAPGGNaGVVLLLVGAALGAVFTF 424

                        250
                 ....*....|..
gi 237641919 398 SYSGRYVFSGII 409
Cdd:PRK12650 425 AYSARLVLGAFV 436
PRK06459 PRK06459
hydrogenase 4 subunit B; Validated
 174-242 3.91e-03

hydrogenase 4 subunit B; Validated


Pssm-ID: 235806 [Multi-domain]  Cd Length: 585  Bit Score: 39.39  E-value: 3.91e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 237641919 174 VVLSVMFITKIPLFPFHV--WLPIVHAEASSPVSVCLSGYIMKLGILGVCRFCSAILPDLVFSSGYVLLCI 242
Cdd:PRK06459 162 ILASFGFIIKMGMMPFLVseWLPIAHGNAPSNFSAILSATMTLMGVYGILKMTILTQTIPIGYFGLTILAI 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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