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Conserved domains on  [gi|68387617|ref|XP_693134|]
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bromo adjacent homology domain-containing 1 protein isoform X2 [Danio rerio]

Protein Classification

BAH_BAHCC1 domain-containing protein( domain architecture ID 10140545)

BAH_BAHCC1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 659-767 1.21e-51

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


:

Pssm-ID: 240065  Cd Length: 121  Bit Score: 176.05  E-value: 1.21e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSGPRKKsLPYVAKVSAFWDDPEsGELMMSLFWYYRPEHTQGGRIPSmHCENEIFASRHQDENSVACI 738
Cdd:cd04714   1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDPE-GNMVVRVKWYYRPEETKGGRKPN-HGEKELFASDHQDENSVQTI 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 68387617 739 EDKCYVLTLAQY---------------CRFCALVKCREEGFPKR 767
Cdd:cd04714  78 EHKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGMLKC 121
 
Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 659-767 1.21e-51

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240065  Cd Length: 121  Bit Score: 176.05  E-value: 1.21e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSGPRKKsLPYVAKVSAFWDDPEsGELMMSLFWYYRPEHTQGGRIPSmHCENEIFASRHQDENSVACI 738
Cdd:cd04714   1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDPE-GNMVVRVKWYYRPEETKGGRKPN-HGEKELFASDHQDENSVQTI 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 68387617 739 EDKCYVLTLAQY---------------CRFCALVKCREEGFPKR 767
Cdd:cd04714  78 EHKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGMLKC 121
BAH smart00439
Bromo adjacent homology domain;
662-809 2.75e-15

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 72.71  E-value: 2.75e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617    662 IRVRDTVLLRSgPRKKSLPYVAKVSAFWDDPESGELMM-SLFWYYRPEHTQGGRiPSMHCENEIFASRHQDENSVACIED 740
Cdd:smart00439   2 ISVGDFVLVEP-DDADEPYYIGRIEEIFETKKNSESKMvRVRWFYRPEETVLEK-AALFDKNEVFLSDEYDTVPLSDIIG 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 68387617    741 KCYVLTLAQYCrfcalvKCREEGfpkrsplvppssyvipahrcvpnDIDPDLVFVCRHVYDFRYGRLLK 809
Cdd:smart00439  80 KCNVLYKSDYP------GLRPEG-----------------------SIGEPDVFFCESAYDPEKGSFKK 119
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 660-810 1.03e-14

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 71.18  E-value: 1.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617   660 EVIRVRDTVLLRSGPRKKSlPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGgRIPSMHCENEIFASRHQDENSVACIE 739
Cdd:pfam01426   1 ETYSVGDFVLVEPDDADEP-YYVARIEELFEDTKNGKKMVRVQWFYRPEETVH-RAGKAFNKDELFLSDEEDDVPLSAII 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 68387617   740 DKCYVLTLAQYCrfcalvkcreegfpkrsplvppssyvipahRCVPNDIDPDLVFVCRHVYDFRYGRLLKN 810
Cdd:pfam01426  79 GKCSVLHKSDLE------------------------------SLDPYKIKEPDDFFCELLYDPKTKSFKKL 119
 
Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 659-767 1.21e-51

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240065  Cd Length: 121  Bit Score: 176.05  E-value: 1.21e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSGPRKKsLPYVAKVSAFWDDPEsGELMMSLFWYYRPEHTQGGRIPSmHCENEIFASRHQDENSVACI 738
Cdd:cd04714   1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDPE-GNMVVRVKWYYRPEETKGGRKPN-HGEKELFASDHQDENSVQTI 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 68387617 739 EDKCYVLTLAQY---------------CRFCALVKCREEGFPKR 767
Cdd:cd04714  78 EHKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGMLKC 121
BAH cd04370
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ...
 659-801 6.35e-18

BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.


Pssm-ID: 239835 [Multi-domain]  Cd Length: 123  Bit Score: 80.51  E-value: 6.35e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSGPRKKSL-PYVAKVSAFWDDPEsGELMMSLFWYYRPEHTQGGRIPSmHCENEIFASRHQDENSVAC 737
Cdd:cd04370   1 GITYEVGDSVYVEPDDSIKSDpPYIARIEELWEDTN-GSKQVKVRWFYRPEETPKGLSPF-ALRRELFLSDHLDEIPVES 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 68387617 738 IEDKCYVLTLAQYCRFCALvkcreegfpkrsplvppssyvipahrcvPNDIDPDlVFVCRHVYD 801
Cdd:cd04370  79 IIGKCKVLFVSEFEGLKQR----------------------------PNKIDTD-DFFCRLAYD 113
BAH smart00439
Bromo adjacent homology domain;
662-809 2.75e-15

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 72.71  E-value: 2.75e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617    662 IRVRDTVLLRSgPRKKSLPYVAKVSAFWDDPESGELMM-SLFWYYRPEHTQGGRiPSMHCENEIFASRHQDENSVACIED 740
Cdd:smart00439   2 ISVGDFVLVEP-DDADEPYYIGRIEEIFETKKNSESKMvRVRWFYRPEETVLEK-AALFDKNEVFLSDEYDTVPLSDIIG 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 68387617    741 KCYVLTLAQYCrfcalvKCREEGfpkrsplvppssyvipahrcvpnDIDPDLVFVCRHVYDFRYGRLLK 809
Cdd:smart00439  80 KCNVLYKSDYP------GLRPEG-----------------------SIGEPDVFFCESAYDPEKGSFKK 119
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 660-810 1.03e-14

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 71.18  E-value: 1.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617   660 EVIRVRDTVLLRSGPRKKSlPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGgRIPSMHCENEIFASRHQDENSVACIE 739
Cdd:pfam01426   1 ETYSVGDFVLVEPDDADEP-YYVARIEELFEDTKNGKKMVRVQWFYRPEETVH-RAGKAFNKDELFLSDEEDDVPLSAII 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 68387617   740 DKCYVLTLAQYCrfcalvkcreegfpkrsplvppssyvipahRCVPNDIDPDLVFVCRHVYDFRYGRLLKN 810
Cdd:pfam01426  79 GKCSVLHKSDLE------------------------------SLDPYKIKEPDDFFCELLYDPKTKSFKKL 119
BAH_polybromo cd04717
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human ...
 659-801 2.25e-11

BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional regulation. Saccharomyces cerevisiae RSC1 and RSC2 are part of the 15-subunit nucleosome remodeling RSC complex. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240068  Cd Length: 121  Bit Score: 61.45  E-value: 2.25e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSgPRKKSLPYVAKVSAFWDDPEsGELMMSLFWYYRPE---HTQGgripSMHCENEIFASRHQDENSV 735
Cdd:cd04717   1 GLQYRVGDCVYVAN-PEDPSKPIIFRIERLWKDED-GEKFFFGCWFYRPEetfHEPT----RKFYKNEVFKSPLYETVPV 74

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 68387617 736 ACIEDKCYVLTLAQYCrfcalvKCREEGFPkrsplvppssyvipahrcvpndiDPDlVFVCRHVYD 801
Cdd:cd04717  75 EEIVGKCAVMDVKDYI------KGRPTEIS-----------------------EED-VYVCESRYN 110
BAH_plant_3 cd04713
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 645-801 2.74e-11

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240064  Cd Length: 146  Bit Score: 62.10  E-value: 2.74e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 645 SASLRRC-YEGVQRDGEVIRVRDTVLLRsgPRKKSLPYVAKVSAFWDDpESGELMMSLFWYYRPEHTQGGRIPSMHCE-- 721
Cdd:cd04713   3 KGKKKKChYTSFEKDGNKYRLEDCVLLV--PEDDQKPYIAIIKDIYKQ-EEGSLKLEVQWLYRPEEIEKKKGGNWKAEdp 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 722 NEIFASRHQDENSVACIEDKCYVltlaqycrfcalvkcreegfpkrsplvppssYVIPAHRCVPNDIDPDlVFVCRHVYD 801
Cdd:cd04713  80 RELFYSFHRDEVPAESVLHPCKV-------------------------------AFVPKGKQIPLRKGHS-GFIVRRVYD 127
BAH_plantDCM_I cd04716
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ...
 659-785 2.33e-05

BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240067  Cd Length: 122  Bit Score: 44.36  E-value: 2.33e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 659 GEVIRVRDTVLLRSGPRKKslPYVAKVSAFWDDPEsGELMMSLFWYYRPEHTQGGRIPSMHCENEIFASRHQDENSVACI 738
Cdd:cd04716   1 GITYNLGDDAYVQGGEGEE--PFICKITEFFEGTD-GKTYFTAQWFYRAEDTVIERQATNHDKKRVFYSEIKNDNPLDCL 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 68387617 739 EDKCYVLTLAQycrfcalvkcrEEGFPKRSPLVPPSSYVIPAHRCVP 785
Cdd:cd04716  78 ISKVKILQVPP-----------NVGTKRKKPNSEKCDYYYDMEYCVP 113
BAH_plant_1 cd04721
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 657-767 2.94e-05

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240072  Cd Length: 130  Bit Score: 44.36  E-value: 2.94e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 657 RDGEVIRVRDTVLLRSGPRKKslpYVAKVSAFWDDpESGELMMSLFWYYRPEHTQGGRIPSMHCENEIFASRHQDENSVA 736
Cdd:cd04721   3 RNGVTISVHDFVYVLSEEEDR---YVAYIEDLYED-KKGSKMVKVRWFHTTDEVGAALSPDSVNPREIFLSPNLQVISVE 78

                        90       100       110
                ....*....|....*....|....*....|.
gi 68387617 737 CIEDKCYVLTLAQYCRFCALVKCREEGFPKR 767
Cdd:cd04721  79 CIDGLATVLTREHYEKFQSVPKNSSELQAYF 109
BAH_Orc1p_like cd04715
BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of ...
 650-752 1.27e-03

BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae Orc1p and similar proteins. Orc1 is part of the Yeast Sir1-origin recognition complex, the Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240066  Cd Length: 159  Bit Score: 40.18  E-value: 1.27e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 650 RCYEGVQRDGEVIRVRDTVLLRSGprkKSLPYVAKVSAFWDDP-ESGELMMSLFWYYRP-----EHTQggrIPSMHCeNE 723
Cdd:cd04715  18 QFYRSFTYDGVEYRLYDDVYVHNG---DSEPYIGKIIKIYETAiDSGKKKVKVIWFFRPseirmELKG---EPKRHI-NE 90

                        90       100       110
                ....*....|....*....|....*....|....
gi 68387617 724 IFASRHQDE-----NSVACIEDKCYVLTLAQYCR 752
Cdd:cd04715  91 VFLACGRGEglaniNLLESIIGKCNVVCISEDFR 124
BAH_MTA cd04709
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The ...
 663-744 6.36e-03

BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240060  Cd Length: 164  Bit Score: 38.14  E-value: 6.36e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 68387617 663 RVRDTVLLRSGPrkkSLPYV-AKVSAFwDDPESGELMMSLFWYYR----PEH-------------TQGGRIPSMHCEN-- 722
Cdd:cd04709   5 RVGDYVYFESSP---NNPYLiRRIEEL-NKTARGHVEAKVVCYYRrrdiPDSlyqladqhrreleEKSDDLTPKQRHQlr 80

                        90       100
                ....*....|....*....|....
gi 68387617 723 --EIFASRHQDENSVACIEDKCYV 744
Cdd:cd04709  81 hrELFLSRQVETLPATHIRGKCSV 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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