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Conserved domains on  [gi|1958777767|ref|XP_038966411|]
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GPI mannosyltransferase 2 isoform X4 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 25-118 2.78e-11

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member pfam04188:

Pssm-ID: 473917  Cd Length: 439  Bit Score: 58.77  E-value: 2.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958777767  25 LQVLTRLLgSSTPITYWFPAYLLQDREpllrcvdTAPQKLLENSPpgqkaprncVMKLLYNWKTCSpvtkcilvyflTYW 104
Cdd:pfam04188 374 VQVLTRFL-SFLPLHYWFLADLLVSDK-------KKMWNPLGDDK---------IVKFYIYWLACS-----------FYI 425

                          90
                  ....*....|....
gi 1958777767 105 LLGLIMHCNFLPWT 118
Cdd:pfam04188 426 LLGTLLFANFLPPT 439
 
Name Accession Description Interval E-value
Mannosyl_trans2 pfam04188
Mannosyltransferase (PIG-V); This is a family of eukaryotic ER membrane proteins that are ...
 25-118 2.78e-11

Mannosyltransferase (PIG-V); This is a family of eukaryotic ER membrane proteins that are involved in the synthesis of glycosylphosphatidylinositol (GPI), a glycolipid that anchors many proteins to the eukaryotic cell surface. Proteins in this family are involved in transferring the second mannose in the biosynthetic pathway of GPI.


Pssm-ID: 282094  Cd Length: 439  Bit Score: 58.77  E-value: 2.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958777767  25 LQVLTRLLgSSTPITYWFPAYLLQDREpllrcvdTAPQKLLENSPpgqkaprncVMKLLYNWKTCSpvtkcilvyflTYW 104
Cdd:pfam04188 374 VQVLTRFL-SFLPLHYWFLADLLVSDK-------KKMWNPLGDDK---------IVKFYIYWLACS-----------FYI 425

                          90
                  ....*....|....
gi 1958777767 105 LLGLIMHCNFLPWT 118
Cdd:pfam04188 426 LLGTLLFANFLPPT 439
 
Name Accession Description Interval E-value
Mannosyl_trans2 pfam04188
Mannosyltransferase (PIG-V); This is a family of eukaryotic ER membrane proteins that are ...
 25-118 2.78e-11

Mannosyltransferase (PIG-V); This is a family of eukaryotic ER membrane proteins that are involved in the synthesis of glycosylphosphatidylinositol (GPI), a glycolipid that anchors many proteins to the eukaryotic cell surface. Proteins in this family are involved in transferring the second mannose in the biosynthetic pathway of GPI.


Pssm-ID: 282094  Cd Length: 439  Bit Score: 58.77  E-value: 2.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958777767  25 LQVLTRLLgSSTPITYWFPAYLLQDREpllrcvdTAPQKLLENSPpgqkaprncVMKLLYNWKTCSpvtkcilvyflTYW 104
Cdd:pfam04188 374 VQVLTRFL-SFLPLHYWFLADLLVSDK-------KKMWNPLGDDK---------IVKFYIYWLACS-----------FYI 425

                          90
                  ....*....|....
gi 1958777767 105 LLGLIMHCNFLPWT 118
Cdd:pfam04188 426 LLGTLLFANFLPPT 439
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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