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Conserved domains on  [gi|1958776266|ref|XP_038965812|]
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pappalysin-1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
myxo_disulf_rpt TIGR02232
Myxococcus cysteine-rich repeat; This model represents a sequence region shared between ...
 246-285 1.23e-12

Myxococcus cysteine-rich repeat; This model represents a sequence region shared between several proteins of Myxococcus xanthus DK 1622 and some eukaryotic proteins that include human pappalysin-1 (SP|Q13219). The region of about 40 amino acids contains several conserved Cys residues presumed to form disulfide bonds. The region appears in up to 13 repeats in Myxococcus.


:

Pssm-ID: 200169 [Multi-domain]  Cd Length: 38  Bit Score: 62.78  E-value: 1.23e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958776266 246 SGYCGDGVIQKdqGEECDDMNKVNGDGCSLFCKQEVSFNC 285
Cdd:TIGR02232   1 APTCGDGIIEP--GEECDDGNTTSGDGCSATCRLEEGFAC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
717-773 1.33e-10

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.33e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776266 717 CDPPPPKFHGLYQCT-NGFQFNSECRIKCEDSDASQGrgSNTIHCRKDGTWSGSFHVC 773
Cdd:pfam00084   1 CPPPPDIPNGKVSATkNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
NL smart00004
Domain found in Notch and Lin-12; The Notch protein is essential for the proper ...
 849-885 1.50e-07

Domain found in Notch and Lin-12; The Notch protein is essential for the proper differentiation of the Drosophila ectoderm. This protein contains 3 NL domains.


:

Pssm-ID: 197463  Cd Length: 38  Bit Score: 48.48  E-value: 1.50e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958776266  849 PHPARIHC-VKGCEPFMGDNYCDAINNRAFCNYDGGDC 885
Cdd:smart00004   1 PQDPWSRCeDAQCWDKFGDGVCDEECNNAECLWDGGDC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
648-711 1.70e-06

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 1.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776266 648 CLAPPPVPNADLQtarCRENKHKVGSLCKYKCKPGYHVPGSSrkskkrafKTQCTQDGSWQEGT 711
Cdd:pfam00084   1 CPPPPDIPNGKVS---ATKNEYNYGASVSYECDPGYRLVGSP--------TITCQEDGTWSPPF 53
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 512-641 1.56e-03

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.56  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 512 CEATDCPEL-TVENASLNCSSSHRYHGAQCTVSCQTGYVLqiqrddeliksqVGPSvTVTCTEGKWNKQVACEPVDCGIP 590
Cdd:PHA02927  143 CESVKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGYSL------------IGNS-GVLCSGGEWSDPPTCQIVKCPHP 209

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958776266 591 DHHHVYAASfSCPEGTTFGRRCSFQCRHPAQLKGNNSFlTCMEDGLWSfPE 641
Cdd:PHA02927  210 TISNGYLSS-GFKRSYSYNDNVDFKCKYGYKLSGSSSS-TCSPGNTWQ-PE 257
 
Name Accession Description Interval E-value
myxo_disulf_rpt TIGR02232
Myxococcus cysteine-rich repeat; This model represents a sequence region shared between ...
 246-285 1.23e-12

Myxococcus cysteine-rich repeat; This model represents a sequence region shared between several proteins of Myxococcus xanthus DK 1622 and some eukaryotic proteins that include human pappalysin-1 (SP|Q13219). The region of about 40 amino acids contains several conserved Cys residues presumed to form disulfide bonds. The region appears in up to 13 repeats in Myxococcus.


Pssm-ID: 200169 [Multi-domain]  Cd Length: 38  Bit Score: 62.78  E-value: 1.23e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958776266 246 SGYCGDGVIQKdqGEECDDMNKVNGDGCSLFCKQEVSFNC 285
Cdd:TIGR02232   1 APTCGDGIIEP--GEECDDGNTTSGDGCSATCRLEEGFAC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
717-773 1.33e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.33e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776266 717 CDPPPPKFHGLYQCT-NGFQFNSECRIKCEDSDASQGrgSNTIHCRKDGTWSGSFHVC 773
Cdd:pfam00084   1 CPPPPDIPNGKVSATkNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
NL smart00004
Domain found in Notch and Lin-12; The Notch protein is essential for the proper ...
 849-885 1.50e-07

Domain found in Notch and Lin-12; The Notch protein is essential for the proper differentiation of the Drosophila ectoderm. This protein contains 3 NL domains.


Pssm-ID: 197463  Cd Length: 38  Bit Score: 48.48  E-value: 1.50e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958776266  849 PHPARIHC-VKGCEPFMGDNYCDAINNRAFCNYDGGDC 885
Cdd:smart00004   1 PQDPWSRCeDAQCWDKFGDGVCDEECNNAECLWDGGDC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
648-711 1.70e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 1.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776266 648 CLAPPPVPNADLQtarCRENKHKVGSLCKYKCKPGYHVPGSSrkskkrafKTQCTQDGSWQEGT 711
Cdd:pfam00084   1 CPPPPDIPNGKVS---ATKNEYNYGASVSYECDPGYRLVGSP--------TITCQEDGTWSPPF 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 648-723 1.70e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.92  E-value: 1.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776266 648 CLAPPPVPNADLqtaRCRENKHKVGSLCKYKCKPGYHVPGSSRkskkrafkTQCTQDGSWqegtcvpvtcDPPPPK 723
Cdd:cd00033     1 CPPPPVPENGTV---TGSKGSYSYGSTVTYSCNEGYTLVGSST--------ITCTENGGW----------SPPPPT 55
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 717-774 3.52e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 3.52e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958776266 717 CDPPPPKFHGLYQCTNG-FQFNSECRIKCEdsdasQG---RGSNTIHCRKDGTWSGSFHVCR 774
Cdd:cd00033     1 CPPPPVPENGTVTGSKGsYSYGSTVTYSCN-----EGytlVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 648-707 2.00e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 2.00e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266  648 CLAPPPVPNAdlqTARCRENKHKVGSLCKYKCKPGYHVPGSSRkskkrafkTQCTQDGSW 707
Cdd:smart00032   1 CPPPPDIENG---TVTSSSGTYSYGDTVTYSCDPGYTLIGSST--------ITCLENGTW 49
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 717-773 5.72e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 5.72e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776266  717 CDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSdaSQGRGSNTIHCRKDGTWSGSFHVC 773
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPG--YTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 560-773 6.45e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 42.72  E-value: 6.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 560 KSQVGPsVTVTCTEGKWNKQVACEPVDCGIP---DHHHVYAAsfscpeGTTFGRRCSFQCRHPAQLKG-NNSFLTCMEDG 635
Cdd:PHA02927   60 KQKMGP-IYAKCTGTGWTLFNQCIKRRCPSPrdiDNGQLDIG------GVDFGSSITYSCNSGYQLIGeSKSYCELGSTG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 636 --LWSFPEALCE-LMCLAPPPVPNAdlqTARCRENKHKVGSLCKYKCKPGYHVPGSSrkskkrafKTQCTqDGSWQE-GT 711
Cdd:PHA02927  133 smVWNPEAPICEsVKCQSPPSISNG---RHNGYEDFYTDGSVVTYSCNSGYSLIGNS--------GVLCS-GGEWSDpPT 200

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776266 712 CVPVTCdpPPPKFHGLYqCTNGFQ----FNSECRIKCEDSDASQGRGSNTihCRKDGTWSGSFHVC 773
Cdd:PHA02927  201 CQIVKC--PHPTISNGY-LSSGFKrsysYNDNVDFKCKYGYKLSGSSSST--CSPGNTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 512-641 1.56e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.56  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 512 CEATDCPEL-TVENASLNCSSSHRYHGAQCTVSCQTGYVLqiqrddeliksqVGPSvTVTCTEGKWNKQVACEPVDCGIP 590
Cdd:PHA02927  143 CESVKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGYSL------------IGNS-GVLCSGGEWSDPPTCQIVKCPHP 209

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958776266 591 DHHHVYAASfSCPEGTTFGRRCSFQCRHPAQLKGNNSFlTCMEDGLWSfPE 641
Cdd:PHA02927  210 TISNGYLSS-GFKRSYSYNDNVDFKCKYGYKLSGSSSS-TCSPGNTWQ-PE 257
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 517-577 3.79e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.29  E-value: 3.79e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776266 517 CPELTV-ENASLNCSSSHRYHGAQCTVSCQTGYVLqiqrddeliksqVGPSvTVTCTE-GKWN 577
Cdd:cd00033     1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTL------------VGSS-TITCTEnGGWS 50
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 587-644 7.62e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.58  E-value: 7.62e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776266  587 CGIPDHhhVYAASFSCPEGT-TFGRRCSFQCRHPAQLKGNNSfLTCMEDGLWSFPEALC 644
Cdd:smart00032   1 CPPPPD--IENGTVTSSSGTySYGDTVTYSCDPGYTLIGSST-ITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
myxo_disulf_rpt TIGR02232
Myxococcus cysteine-rich repeat; This model represents a sequence region shared between ...
 246-285 1.23e-12

Myxococcus cysteine-rich repeat; This model represents a sequence region shared between several proteins of Myxococcus xanthus DK 1622 and some eukaryotic proteins that include human pappalysin-1 (SP|Q13219). The region of about 40 amino acids contains several conserved Cys residues presumed to form disulfide bonds. The region appears in up to 13 repeats in Myxococcus.


Pssm-ID: 200169 [Multi-domain]  Cd Length: 38  Bit Score: 62.78  E-value: 1.23e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958776266 246 SGYCGDGVIQKdqGEECDDMNKVNGDGCSLFCKQEVSFNC 285
Cdd:TIGR02232   1 APTCGDGIIEP--GEECDDGNTTSGDGCSATCRLEEGFAC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
717-773 1.33e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.33e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776266 717 CDPPPPKFHGLYQCT-NGFQFNSECRIKCEDSDASQGrgSNTIHCRKDGTWSGSFHVC 773
Cdd:pfam00084   1 CPPPPDIPNGKVSATkNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
NL smart00004
Domain found in Notch and Lin-12; The Notch protein is essential for the proper ...
 849-885 1.50e-07

Domain found in Notch and Lin-12; The Notch protein is essential for the proper differentiation of the Drosophila ectoderm. This protein contains 3 NL domains.


Pssm-ID: 197463  Cd Length: 38  Bit Score: 48.48  E-value: 1.50e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958776266  849 PHPARIHC-VKGCEPFMGDNYCDAINNRAFCNYDGGDC 885
Cdd:smart00004   1 PQDPWSRCeDAQCWDKFGDGVCDEECNNAECLWDGGDC 38
Sushi pfam00084
Sushi repeat (SCR repeat);
648-711 1.70e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 1.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958776266 648 CLAPPPVPNADLQtarCRENKHKVGSLCKYKCKPGYHVPGSSrkskkrafKTQCTQDGSWQEGT 711
Cdd:pfam00084   1 CPPPPDIPNGKVS---ATKNEYNYGASVSYECDPGYRLVGSP--------TITCQEDGTWSPPF 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 648-723 1.70e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.92  E-value: 1.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776266 648 CLAPPPVPNADLqtaRCRENKHKVGSLCKYKCKPGYHVPGSSRkskkrafkTQCTQDGSWqegtcvpvtcDPPPPK 723
Cdd:cd00033     1 CPPPPVPENGTV---TGSKGSYSYGSTVTYSCNEGYTLVGSST--------ITCTENGGW----------SPPPPT 55
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 717-774 3.52e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 3.52e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958776266 717 CDPPPPKFHGLYQCTNG-FQFNSECRIKCEdsdasQG---RGSNTIHCRKDGTWSGSFHVCR 774
Cdd:cd00033     1 CPPPPVPENGTVTGSKGsYSYGSTVTYSCN-----EGytlVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 648-707 2.00e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 2.00e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266  648 CLAPPPVPNAdlqTARCRENKHKVGSLCKYKCKPGYHVPGSSRkskkrafkTQCTQDGSW 707
Cdd:smart00032   1 CPPPPDIENG---TVTSSSGTYSYGDTVTYSCDPGYTLIGSST--------ITCLENGTW 49
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 717-773 5.72e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 5.72e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958776266  717 CDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSdaSQGRGSNTIHCRKDGTWSGSFHVC 773
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPG--YTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 560-773 6.45e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 42.72  E-value: 6.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 560 KSQVGPsVTVTCTEGKWNKQVACEPVDCGIP---DHHHVYAAsfscpeGTTFGRRCSFQCRHPAQLKG-NNSFLTCMEDG 635
Cdd:PHA02927   60 KQKMGP-IYAKCTGTGWTLFNQCIKRRCPSPrdiDNGQLDIG------GVDFGSSITYSCNSGYQLIGeSKSYCELGSTG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 636 --LWSFPEALCE-LMCLAPPPVPNAdlqTARCRENKHKVGSLCKYKCKPGYHVPGSSrkskkrafKTQCTqDGSWQE-GT 711
Cdd:PHA02927  133 smVWNPEAPICEsVKCQSPPSISNG---RHNGYEDFYTDGSVVTYSCNSGYSLIGNS--------GVLCS-GGEWSDpPT 200

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958776266 712 CVPVTCdpPPPKFHGLYqCTNGFQ----FNSECRIKCEDSDASQGRGSNTihCRKDGTWSGSFHVC 773
Cdd:PHA02927  201 CQIVKC--PHPTISNGY-LSSGFKrsysYNDNVDFKCKYGYKLSGSSSST--CSPGNTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 512-641 1.56e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.56  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 512 CEATDCPEL-TVENASLNCSSSHRYHGAQCTVSCQTGYVLqiqrddeliksqVGPSvTVTCTEGKWNKQVACEPVDCGIP 590
Cdd:PHA02927  143 CESVKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGYSL------------IGNS-GVLCSGGEWSDPPTCQIVKCPHP 209

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958776266 591 DHHHVYAASfSCPEGTTFGRRCSFQCRHPAQLKGNNSFlTCMEDGLWSfPE 641
Cdd:PHA02927  210 TISNGYLSS-GFKRSYSYNDNVDFKCKYGYKLSGSSSS-TCSPGNTWQ-PE 257
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 517-577 3.79e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.29  E-value: 3.79e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958776266 517 CPELTV-ENASLNCSSSHRYHGAQCTVSCQTGYVLqiqrddeliksqVGPSvTVTCTE-GKWN 577
Cdd:cd00033     1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTL------------VGSS-TITCTEnGGWS 50
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 587-645 5.40e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.90  E-value: 5.40e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958776266 587 CGIPDHhhVYAASFSCPEGT-TFGRRCSFQCRHPAQLKGNNSfLTCMEDGLWSFPEALCE 645
Cdd:cd00033     1 CPPPPV--PENGTVTGSKGSySYGSTVTYSCNEGYTLVGSST-ITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 587-644 7.62e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.58  E-value: 7.62e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958776266  587 CGIPDHhhVYAASFSCPEGT-TFGRRCSFQCRHPAQLKGNNSfLTCMEDGLWSFPEALC 644
Cdd:smart00032   1 CPPPPD--IENGTVTSSSGTySYGDTVTYSCDPGYTLIGSST-ITCLENGTWSPPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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