|
Name |
Accession |
Description |
Interval |
E-value |
| ATG11 |
pfam10377 |
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, ... |
1258-1384 |
1.79e-26 |
|
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, Schizosaccharomyces pombe, this protein has been shown to interact with the telomere cap complex and it is also required for dimerization and kinase activation of Atg1. However, in budding yeast, Saccharomyces cerevisiae, this protein is called ATG11 and is shown to be involved in autophagy.
Pssm-ID: 463063 Cd Length: 130 Bit Score: 105.76 E-value: 1.79e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1258 LERTLQlKEEENKRlnqrlmsQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDN-----YVLFTVSPTLYFLHSESLP 1332
Cdd:pfam10377 14 LAKKLT-KENKSKR-------EKLEKLQSEAHEKITLKNFKVGDLALFLPTRRHNDlstppWAAFNVGAPHYFLKADSLL 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1958775931 1333 ALdlkpgegasgvSRRPWVLGKVMEKEYCQAK---KAQNRFKVPLGTKFYRVKAV 1384
Cdd:pfam10377 86 AL-----------KSREWFVGRITSIEERVVDlsdKDSNPFKLSKGTVWYLVTAE 129
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
745-1113 |
1.81e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.86 E-value: 1.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 745 QNSEIKELKQSREMVLEDLKKLHDEkIESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHKVSLEKLKKEnQQKID 824
Cdd:TIGR02168 675 RRREIEELEEKIEELEEKIAELEKA-LAELRKELEELEEE-LEQLRKEL-----EELSRQISALRKDLARLEAE-VEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 825 QMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslleqetenLRTEINK 904
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE------------LRAELTL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 905 LNQKIHDNSESYQVGLSELRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSE 984
Cdd:TIGR02168 815 LNEEAANLRERLESLERRIAAT---------ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 985 LSALEKQKDEKITQQEEkykalIQNLEKDKQRLamnheqdkEQLIQKLNfEKDEAIQTALDEFKLERELVEKELLEKVK- 1063
Cdd:TIGR02168 886 EEALALLRSELEELSEE-----LRELESKRSEL--------RRELEELR-EKLAQLELRLEGLEVRIDNLQERLSEEYSl 951
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1958775931 1064 HLENQIAKSPAFESAREDSSSLVAELQEKLQE-----EKAkfLEQLEEQEKRKNE 1113
Cdd:TIGR02168 952 TLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnLAA--IEEYEELKERYDF 1004
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
666-1172 |
2.32e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 75.06 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 666 QELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQklleMENIMHTQ 745
Cdd:TIGR04523 162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQ----LKDNIEKK 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 746 NSEIKELK---QSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKeledtlhirhTEEFEKVITDHKVSLEKLKKENQQK 822
Cdd:TIGR04523 238 QQEINEKTteiSNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK----------IKELEKQLNQLKSEISDLNNQKEQD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 823 IDQMLESHASAIQEKEQQLQ----ELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEEsRTQQKETLKSLLE---QET 895
Cdd:TIGR04523 308 WNKELKSELKNQEKKLEEIQnqisQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-KQNEIEKLKKENQsykQEI 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 896 ENLRTEINKLNQKIHDNSESYQvglselrslmtiEKDQCISELisrhEEESNILKAELDSVTALHHQAFEIEKKLKEQIV 975
Cdd:TIGR04523 387 KNLESQINDLESKIQNQEKLNQ------------QKDEQIKKL----QQEKELLEKEIERLKETIIKNNSEIKDLTNQDS 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 976 ELQTKLNsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAmnheqDKEQLIQKLNFEKdeaiqtaldefklerelve 1055
Cdd:TIGR04523 451 VKELIIK-NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK-----SKEKELKKLNEEK------------------- 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1056 KELLEKVKHLENQIAKSpafesaredssslvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA----------E 1125
Cdd:TIGR04523 506 KELEEKVKDLTKKISSL--------------KEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEkeideknkeiE 571
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1958775931 1126 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR04523 572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
672-1173 |
3.50e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 74.29 E-value: 3.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 672 KIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKE 751
Cdd:TIGR04523 119 KNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 752 LKQsREMVLEDLKKLHDE---KIESLRAEFQCLEQNhLKELEDTLHIRHTE--EFEKVITDHKVSLEKLKKENQQKIDQm 826
Cdd:TIGR04523 199 LEL-LLSNLKKKIQKNKSlesQISELKKQNNQLKDN-IEKKQQEINEKTTEisNTQTQLNQLKDEQNKIKKQLSEKQKE- 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 827 LESHASAIQEKEQQLQELKVKVSDLSdmrcklevelalKEAETDEIKILLEESRTQQKEtlKSLLEQETENLRTEINKLN 906
Cdd:TIGR04523 276 LEQNNKKIKELEKQLNQLKSEISDLN------------NQKEQDWNKELKSELKNQEKK--LEEIQNQISQNNKIISQLN 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 907 QKIHDNSESYQVGLSElrslmTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQiVELQTKLNSELS 986
Cdd:TIGR04523 342 EQISQLKKELTNSESE-----NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ-EKLNQQKDEQIK 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 987 ALEKQKdEKITQQEEKYKALIQNLEKDKQRLAmNHEQDKEQLIQKLNFEKDEaIQTALDEFKLERELVEKELLEKVKHLE 1066
Cdd:TIGR04523 416 KLQQEK-ELLEKEIERLKETIIKNNSEIKDLT-NQDSVKELIIKNLDNTRES-LETQLKVLSRSINKIKQNLEQKQKELK 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1067 NQIAKSPAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIIN 1146
Cdd:TIGR04523 493 SKEKELKKLNEEKKELEEKVKDLTKKISSLKEK-IEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIE 571
|
490 500
....*....|....*....|....*..
gi 1958775931 1147 DLSDKLKSTMQQQERDKDLIESLSEDR 1173
Cdd:TIGR04523 572 ELKQTQKSLKKKQEEKQELIDQKEKEK 598
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
629-1119 |
3.75e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 74.29 E-value: 3.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 629 KEQCDLSNYLKCTAVEIRNI---IDKVKCSL--------EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLK 697
Cdd:TIGR04523 166 KQKEELENELNLLEKEKLNIqknIDKIKNKLlklelllsNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKT 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 698 EDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVL-----EDLKKlHDEKIE 772
Cdd:TIGR04523 246 TEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWnkelkSELKN-QEKKLE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 773 SLRAEFQCLEQ------NHLKELEDTLHIRHTE--EFEKVITDHKVSLEKLKKENQQKIDQmLESHASAIQEKEQQLQEL 844
Cdd:TIGR04523 325 EIQNQISQNNKiisqlnEQISQLKKELTNSESEnsEKQRELEEKQNEIEKLKKENQSYKQE-IKNLESQINDLESKIQNQ 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 845 KVKVSDLSDMRCKLEVELALKEaetDEIKILLEEsRTQQKETLKSLLEQETEnLRTEINKLNQKIhdnsESYQVGLSELr 924
Cdd:TIGR04523 404 EKLNQQKDEQIKKLQQEKELLE---KEIERLKET-IIKNNSEIKDLTNQDSV-KELIIKNLDNTR----ESLETQLKVL- 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 925 slmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELqTKLNSELSALEKQKDEKITQQEEKYK 1004
Cdd:TIGR04523 474 -----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDL-TKKISSLKEKIEKLESEKKEKESKIS 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1005 ALIQNLEKDKQRLAMNHEQDKEQLIQKlNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSS 1084
Cdd:TIGR04523 542 DLEDELNKDDFELKKENLEKEIDEKNK-EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELE 620
|
490 500 510
....*....|....*....|....*....|....*...
gi 1958775931 1085 LVAELQEKLQEEKAKF---LEQLEEQEKRKNEEMQNVR 1119
Cdd:TIGR04523 621 KAKKENEKLSSIIKNIkskKNKLKQEVKQIKETIKEIR 658
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
827-1110 |
7.46e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.43 E-value: 7.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 827 LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINK 904
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyeLLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 905 LNQKIHDNSESYQVGLSELRSLmtIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSE 984
Cdd:COG1196 307 LEERRRELEERLEELEEELAEL--EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 985 LSALEKQKdekitQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLnfEKDEAIQTALDEFKLERELVEKELLEKVKH 1064
Cdd:COG1196 385 AEELLEAL-----RAAAELAAQLEELEEAEEALLERLERLEEELEELE--EALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1958775931 1065 LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKR 1110
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
857-1171 |
1.54e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.78 E-value: 1.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 857 KLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciS 936
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEE-----LEEELEQLRKELEELSRQISALRKDLARLEAEVEQL---------E 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 937 ELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKdEKITQQEEKYKALIQNLEKDKQR 1016
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1017 LAmNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEK-----ELLEKVKHLENQIAKS-PAFESAREDSSSLVAELQ 1090
Cdd:TIGR02168 826 LE-SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELeelieELESELEALLNERASLeEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1091 EKlqEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLS 1170
Cdd:TIGR02168 905 EL--ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
.
gi 1958775931 1171 E 1171
Cdd:TIGR02168 983 E 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
760-1120 |
3.51e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.63 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 760 LEDLKKLHDEKIESLRAEFQCLEQnhLKELEDTLhirhtEEFEK-VITDHKVSLEKLKKENQQKIDQM---LESHASAIQ 835
Cdd:TIGR02168 191 LEDILNELERQLKSLERQAEKAER--YKELKAEL-----RELELaLLVLRLEELREELEELQEELKEAeeeLEELTAELQ 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 836 EKEQQLQELKVKVSdlsdmrcKLEVELALKEAETDEIKILLEEsrtqqketlkslLEQETENLRTEINKLNQKIhdnsES 915
Cdd:TIGR02168 264 ELEEKLEELRLEVS-------ELEEEIEELQKELYALANEISR------------LEQQKQILRERLANLERQL----EE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 916 YQVGLSELRSlmtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKqkdek 995
Cdd:TIGR02168 321 LEAQLEELES-----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ----- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 996 ITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQlIQKLNFEKDEAiqtALDEFKLERELVEKELLEKVKHLENQIAKSPAF 1075
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLERLEDRRERLQQE-IEELLKKLEEA---ELKELQAELEELEEELEELQEELERLEEALEEL 466
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1958775931 1076 ESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRT 1120
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKA 510
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
657-1174 |
4.00e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 4.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 657 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLL 736
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 737 EMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNHLKELEDTLHIRHT-EEFEKVITDHKVSLEKL 815
Cdd:COG1196 320 ELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEElEELAEELLEALRAAAEL 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 816 KKENQQKIDQM------LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKS 889
Cdd:COG1196 399 AAQLEELEEAEeallerLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 890 L--LEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSvtALHHQAFEIE 967
Cdd:COG1196 479 LaeLLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAA--ALQNIVVEDD 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 968 KKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEF 1047
Cdd:COG1196 557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1048 KLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQ 1127
Cdd:COG1196 637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1958775931 1128 TNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRA 1174
Cdd:COG1196 717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
835-1160 |
6.16e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.74 E-value: 6.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 835 QEKEQQLQELKVKVSdLSDMRcKLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHDNSE 914
Cdd:COG1196 216 RELKEELKELEAELL-LLKLR-ELEAELEELEAELEELEAELEELEAELAE-----LEAELEELRLELEELELELEEAQA 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 915 SYQVGLSELRSLmtiEKDqciselISRHEEESNILKAELDsvtalhhqafeiekKLKEQIVELQTKLNsELSALEKQKDE 994
Cdd:COG1196 289 EEYELLAELARL---EQD------IARLEERRRELEERLE--------------ELEEELAELEEELE-ELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 995 KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDE-AIQTALDEFKLERELVEKELLEKVKHLENQiaksp 1073
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlEALRAAAELAAQLEELEEAEEALLERLERL----- 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1074 afESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLK 1153
Cdd:COG1196 420 --EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
....*..
gi 1958775931 1154 STMQQQE 1160
Cdd:COG1196 498 EAEADYE 504
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
750-1113 |
1.15e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.71 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 750 KELKQSREMVLEDLKKLHDEKiESLRAEFQCLEqNHLKELEDTLhirhtEEFEKVITDHKVSLEKLKKEnQQKIDQMLES 829
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKREL-SSLQSELRRIE-NRLDELSQEL-----SDASRKIGEIEKEIEQLEQE-EEKLKERLEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 830 HASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKI 909
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 910 ---HDNSESYQVGLSELRSLMTIEKDQCISelISRHEEESNILKAELDSVTAlhhqafEIEKKLKEQIVELQtKLNSELS 986
Cdd:TIGR02169 822 nrlTLEKEYLEKEIQELQEQRIDLKEQIKS--IEKEIENLNGKKEELEEELE------ELEAALRDLESRLG-DLKKERD 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 987 ALEKQKDE---KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKEL--LEK 1061
Cdd:TIGR02169 893 ELEAQLRElerKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIraLEP 972
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 1062 VKHLENQiakspAFESAREDSSSLVaELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:TIGR02169 973 VNMLAIQ-----EYEEVLKRLDELK-EKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
644-1190 |
5.54e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 67.40 E-value: 5.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 644 EIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDA 723
Cdd:PRK03918 177 RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRK 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 724 IvcmqhekDQKLLEMENIMHTQNSEIKELKQSREMvLEDLKKLHDE--KIESLRAEFQCLEQNHLKELED-TLHIRHTEE 800
Cdd:PRK03918 257 L-------EEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRlEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 801 FEKVITDHKVSLEKLKKENQQkidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLevelalKEAETDEIKILLEESR 880
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKE-----LEKRLEELEERHELYEEAKAKKEELERLKKRL------TGLTPEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 881 TQQKEtlkslLEQETENLRTEINKLNQKIHDNSESyqvgLSELRSlMTIEKDQCISELISRHEEE-SNILKAELDSVTAL 959
Cdd:PRK03918 398 KAKEE-----IEEEISKITARIGELKKEIKELKKA----IEELKK-AKGKCPVCGRELTEEHRKElLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 960 HHQAFEIEKKLKEQIVELQTKLN--SELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQ----DKEQLIQKLN 1033
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKkeSELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliklKGEIKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1034 FEKDEAIQTALDEFKLERELVEKELLEKVKHLENQiakspAFESAREDSSSLvAELQ------------EKLQEEKAKFL 1101
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEEL-----GFESVEELEERL-KELEpfyneylelkdaEKELEREEKEL 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1102 EQLEEQEKRKNEEMQNVRTSL------IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:PRK03918 622 KKLEEELDKAFEELAETEKRLeelrkeLEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
|
570
....*....|....*
gi 1958775931 1176 LLEEKKKLEEEVSKL 1190
Cdd:PRK03918 702 ELEEREKAKKELEKL 716
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
732-1169 |
6.58e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 66.97 E-value: 6.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 732 DQKLLEMENIMHTQNSEIKELKQsREMVLEDLKKLHDEKIESLRAEFQCLEqnhlKELEDTLHIRHTEEFEkvitdhKVS 811
Cdd:TIGR04523 60 DKNLNKDEEKINNSNNKIKILEQ-QIKDLNDKLKKNKDKINKLNSDLSKIN----SEIKNDKEQKNKLEVE------LNK 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 812 LEKLKKENQQKIDQMLEShasaIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQ--QKETLKS 889
Cdd:TIGR04523 129 LEKQKKENKKNIDKFLTE----IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKllKLELLLS 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 890 LLE---QETENLRTEINKLNQK---IHDNSESYQVGLSELRSLMTIEKDQcISELISRHEEESNILKAELDSVTalhhqa 963
Cdd:TIGR04523 205 NLKkkiQKNKSLESQISELKKQnnqLKDNIEKKQQEINEKTTEISNTQTQ-LNQLKDEQNKIKKQLSEKQKELE------ 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 964 fEIEKKLKEQIVELQtKLNSELSALEKQKDEKITQqeeKYKALIQNLEKDKQRLAM---NHEQDKEQLIQKLNFEKDEAI 1040
Cdd:TIGR04523 278 -QNNKKIKELEKQLN-QLKSEISDLNNQKEQDWNK---ELKSELKNQEKKLEEIQNqisQNNKIISQLNEQISQLKKELT 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1041 QTALDEFKLERELVEKE-LLEKVKHlENQiAKSPAFESAREDSSSLVAEL--QEKLQEEKAKFLEQLEEQEKRKNEEMQN 1117
Cdd:TIGR04523 353 NSESENSEKQRELEEKQnEIEKLKK-ENQ-SYKQEIKNLESQINDLESKIqnQEKLNQQKDEQIKKLQQEKELLEKEIER 430
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 1118 VRTSLIAEQQTNFNtvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESL 1169
Cdd:TIGR04523 431 LKETIIKNNSEIKD--LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
660-1157 |
7.33e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.07 E-value: 7.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 660 LKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKdsefaiiKHEKDAIVCMQhekdqkllemE 739
Cdd:pfam15921 100 LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNT-------VHELEAAKCLK----------E 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 740 NIMHTQNSEIKELkqsREMVLEDLKKLHDekIESLRAEFQCLEQNHLKELED--TLHIRHT-EEFEKVIT--DHKVS--- 811
Cdd:pfam15921 163 DMLEDSNTQIEQL---RKMMLSHEGVLQE--IRSILVDFEEASGKKIYEHDSmsTMHFRSLgSAISKILRelDTEISylk 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 812 ---------LEKLKKENQQKIDQMLESHASAIqekEQQLQELKVKVSDLSDmrcKLEVELALKEAETDEIKILLEESRTQ 882
Cdd:pfam15921 238 grifpvedqLEALKSESQNKIELLLQQHQDRI---EQLISEHEVEITGLTE---KASSARSQANSIQSQLEIIQEQARNQ 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 883 QKETLKSL--LEQETENLRTEINKLNQKIHDNSESYQVGL----SELRSLMTiEKDQciselisrHEEESNILKAELDSV 956
Cdd:pfam15921 312 NSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSELTEART-ERDQ--------FSQESGNLDDQLQKL 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 957 TA-LHHQAFE--IEKKLKEQIVELQTKLNSELSALEKQKDEKiTQQEEKYKALIQNLEKDKQrlamNHEQDKEQLIQKLN 1033
Cdd:pfam15921 383 LAdLHKREKElsLEKEQNKRLWDRDTGNSITIDHLRRELDDR-NMEVQRLEALLKAMKSECQ----GQMERQMAAIQGKN 457
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1034 --FEKDEAIQTALDEfklerelvEKELLEKVkhLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLE--------- 1102
Cdd:pfam15921 458 esLEKVSSLTAQLES--------TKEMLRKV--VEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEitklrsrvd 527
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775931 1103 -QLEEQEKRKNEE--MQNVRTSLIAeqqtnfntvLTREKMRKENIINDLSDKLKSTMQ 1157
Cdd:pfam15921 528 lKLQELQHLKNEGdhLRNVQTECEA---------LKLQMAEKDKVIEILRQQIENMTQ 576
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
944-1175 |
1.15e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.50 E-value: 1.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 944 EESNILKAELdsvTALHHQAFEIE-KKLKEQIVELQTKLNSELSALEkQKDEKITQQEEKYKALIQNLEKDKQRLAmNHE 1022
Cdd:COG1196 220 EELKELEAEL---LLLKLRELEAElEELEAELEELEAELEELEAELA-ELEAELEELRLELEELELELEEAQAEEY-ELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1023 QDKEQLIQKLNFEKDE--AIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKF 1100
Cdd:COG1196 295 AELARLEQDIARLEERrrELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775931 1101 LEQLEEQEKRKNEEMQNVRTSL-IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
737-1161 |
1.30e-10 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 66.22 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 737 EMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLK 816
Cdd:TIGR00606 574 QLEDWLHSKSKEINQTRDRLAKLNKELASLEQNK-NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSS 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 817 KEN----------QQKIDQMLESHASA------IQEKEQQLQE----LKVKVSDLSDMRCKLEVELALKEAETDEIKILL 876
Cdd:TIGR00606 653 KQRamlagatavySQFITQLTDENQSCcpvcqrVFQTEAELQEfisdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 877 EesrtqQKETLKSLLEQETENLRTEINKLNQKIhdnsesyqvglSELRSlmTIEKDQCISELISRHEEESNILKAELDSV 956
Cdd:TIGR00606 733 P-----GRQSIIDLKEKEIPELRNKLQKVNRDI-----------QRLKN--DIEEQETLLGTIMPEEESAKVCLTDVTIM 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 957 TALHHQAFEIEKKLKEQIVELQTklnSELSALEKQKDEKITQQEEKYKALIQNLEKDkQRLAMNHEQDKEQLIQKLNFEK 1036
Cdd:TIGR00606 795 ERFQMELKDVERKIAQQAAKLQG---SDLDRTVQQVNQEKQEKQHELDTVVSKIELN-RKLIQDQQEQIQHLKSKTNELK 870
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1037 DEAIQtaLDEFKLERELVEKELLEKVKHLENQIAkspAFESAREDSSSLvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1116
Cdd:TIGR00606 871 SEKLQ--IGTNLQRRQQFEEQLVELSTEVQSLIR---EIKDAKEQDSPL-ETFLEKDQQEKEELISSKETSNKKAQDKVN 944
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1958775931 1117 NVRTSL---IAEQQTNFNTV---LTREKMRKENIINDLSDKLKSTMQQQER 1161
Cdd:TIGR00606 945 DIKEKVkniHGYMKDIENKIqdgKDDYLKQKETELNTVNAQLEECEKHQEK 995
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
655-1120 |
2.30e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 65.13 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 655 SLEITLKEKHQ---QELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiIKHEKDAIVCMQHEK 731
Cdd:pfam05483 310 STQKALEEDLQiatKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQR---LEKNEDQLKIITMEL 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 732 DQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEK-IESLRAEFQCLEQN------------HLKELEDTLHIRHT 798
Cdd:pfam05483 387 QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKqFEKIAEELKGKEQElifllqarekeiHDLEIQLTAIKTSE 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 799 EEFEKVITDHKVSLEKLKKENQQ---KIDQMLESHASAIQEKEQQLQELKVKVSDLSDmrCKLEVELALKEAETdeikil 875
Cdd:pfam05483 467 EHYLKEVEDLKTELEKEKLKNIEltaHCDKLLLENKELTQEASDMTLELKKHQEDIIN--CKKQEERMLKQIEN------ 538
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 876 LEESRTQQKETLKSLLEqETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCiselisrheeesNILKAELDS 955
Cdd:pfam05483 539 LEEKEMNLRDELESVRE-EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKC------------NNLKKQIEN 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 956 VTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEkITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQlIQKLNFE 1035
Cdd:pfam05483 606 KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELE-LASAKQKFEEIIDNYQKEIEDKKISEEKLLEE-VEKAKAI 683
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1036 KDEAIQTALD-EFKLERELVEK-ELLEKVKH-----LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLE------ 1102
Cdd:pfam05483 684 ADEAVKLQKEiDKRCQHKIAEMvALMEKHKHqydkiIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSlkkqle 763
|
490
....*....|....*....
gi 1958775931 1103 -QLEEQEKRKNEEMQNVRT 1120
Cdd:pfam05483 764 iEKEEKEKLKMEAKENTAI 782
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
661-1174 |
4.95e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.31 E-value: 4.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 661 KEKHQQELQSLKIEYEcklnTLEKDSEENVNKILKLKEDLVSLEEalqnkdsEFAIIKHEKDAIVCMQHEKDQKLLEMEN 740
Cdd:TIGR02168 304 KQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELEELES 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 741 IMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNH------LKELEDTLHIRHTEEFEKVITDHKVSLEK 814
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASL-NNEIERLEARLERLEDRRerlqqeIEELLKKLEEAELKELQAELEELEEELEE 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 815 LKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESR--TQQKETLKSLLE 892
Cdd:TIGR02168 452 LQEELERLEEA-LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglSGILGVLSELIS 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 893 QEtENLRTEINK-----LNQKIHDNSESYQVGLSELRS----------LMTIEKDQCISELISRHEEESNILKAELDSVT 957
Cdd:TIGR02168 531 VD-EGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKQnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 958 A-----------LHH--------QAFEIEKKLKEQ--IVELQTKL------------NSELSALEKQKD-EKITQQEEKY 1003
Cdd:TIGR02168 610 FdpklrkalsylLGGvlvvddldNALELAKKLRPGyrIVTLDGDLvrpggvitggsaKTNSSILERRREiEELEEKIEEL 689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1004 KALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKE-LLEKVKHLENQIAKSPAFESAREDS 1082
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEELEER 769
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1083 sslVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQ--TNFNTVLTREKMRKENIINDLSDKLKS---TMQ 1157
Cdd:TIGR02168 770 ---LEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAelTLLNEEAANLRERLESLERRIAATERRledLEE 845
|
570
....*....|....*..
gi 1958775931 1158 QQERDKDLIESLSEDRA 1174
Cdd:TIGR02168 846 QIEELSEDIESLAAEIE 862
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
866-1194 |
2.47e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 2.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 866 EAETDEIKILLEES------RTQQKETLKSLLEQET-----ENLRTEINKLNQKIHDNSESYQvglsELRSLMTIEKDQC 934
Cdd:TIGR02168 151 EAKPEERRAIFEEAagiskyKERRKETERKLERTREnldrlEDILNELERQLKSLERQAEKAE----RYKELKAELRELE 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 935 ISELISRHEEesniLKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKAL---IQNLE 1011
Cdd:TIGR02168 227 LALLVLRLEE----LREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALaneISRLE 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1012 KDKQRLAMNHEQDKEQlIQKLNFEKDEAIQTaLDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQE 1091
Cdd:TIGR02168 302 QQKQILRERLANLERQ-LEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1092 KLQEEKAKFLeQLEEQEKRKNEEMQNVRTSL--IAEQQTNFNTVLT-----REKMRKENIINDLSDKLKSTMQQQERDKD 1164
Cdd:TIGR02168 380 QLETLRSKVA-QLELQIASLNNEIERLEARLerLEDRRERLQQEIEellkkLEEAELKELQAELEELEEELEELQEELER 458
|
330 340 350
....*....|....*....|....*....|
gi 1958775931 1165 LIESLSEDRARLLEEKKKLEEEVSKLRTSS 1194
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQ 488
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
631-1057 |
3.73e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 3.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 631 QCDLSNYLKCTAVEIRNIIDKVKcsleitlkekhqqelqslkieyecklNTLEKDSeenvnKILKLKEDlvsLEEALQNK 710
Cdd:TIGR02169 141 QGDVTDFISMSPVERRKIIDEIA--------------------------GVAEFDR-----KKEKALEE---LEEVEENI 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 711 DSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQnHLKELE 790
Cdd:TIGR02169 187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI-ERQLASLEEELEKLTE-EISELE 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 791 DTLhirhtEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETD 870
Cdd:TIGR02169 265 KRL-----EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 871 EIKillEESRTQQKEtlKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekDQCISELISRHEEesniLK 950
Cdd:TIGR02169 340 ELE---REIEEERKR--RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY-----REKLEKLKREINE----LK 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 951 AELDSVTALHHQAFEIEKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLamnheQDKEQLIQ 1030
Cdd:TIGR02169 406 RELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL-----YDLKEEYD 479
|
410 420
....*....|....*....|....*..
gi 1958775931 1031 KLNFEKDEaiqtaldefkLERELVEKE 1057
Cdd:TIGR02169 480 RVEKELSK----------LQRELAEAE 496
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
916-1175 |
5.40e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 5.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 916 YQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALE--KQKD 993
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYelLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 994 EKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQ-----KLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQ 1068
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEEleeelEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1069 IAKSPAFESAREDSSSLVAELQEKLQ------EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT--NFNTVLTREKMR 1140
Cdd:COG1196 378 EEELEELAEELLEALRAAAELAAQLEeleeaeEALLERLERLEEELEELEEALAELEEEEEEEEEAleEAAEEEAELEEE 457
|
250 260 270
....*....|....*....|....*....|....*
gi 1958775931 1141 KENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
653-909 |
1.34e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 1.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 653 KCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKD 732
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 733 QKLLEMENIMHTQNSEIKELKQSREMVLEDlkklhdekIESLRAEfqcleQNHLKELEDTLHIRHtEEFEKVITDHKVSL 812
Cdd:TIGR02168 824 ERLESLERRIAATERRLEDLEEQIEELSED--------IESLAAE-----IEELEELIEELESEL-EALLNERASLEEAL 889
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 813 EKLKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELA-LKEAETDEIKILLEESrtqqkETLKSLL 891
Cdd:TIGR02168 890 ALLRSELEELSEE-LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEA-----EALENKI 963
|
250
....*....|....*...
gi 1958775931 892 EQETENLRTEINKLNQKI 909
Cdd:TIGR02168 964 EDDEEEARRRLKRLENKI 981
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
657-1175 |
1.44e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 657 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKD---- 732
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEaqle 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 733 ---QKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLH-------------DEKIESLRAEFQCLEQ------NHLKELE 790
Cdd:TIGR02168 327 eleSKLDELAEELAELEEKLEELKEELESLEAELEELEaeleelesrleelEEQLETLRSKVAQLELqiaslnNEIERLE 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 791 DTLHI--RHTEEFEKVITDHKVSLEKLKKENQQ----KIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELAL 864
Cdd:TIGR02168 407 ARLERleDRRERLQQEIEELLKKLEEAELKELQaeleELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 865 KEAETDEIKILLEESRTQQKETLKSLLEQE---------------TENLRTEINK-----LNQKIHDNSESYQVGLSELR 924
Cdd:TIGR02168 487 LQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvDEGYEAAIEAalggrLQAVVVENLNAAKKAIAFLK 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 925 S----------LMTIEKDQCISELISRHEEESNILKAELDSVTA-----------LHH--------QAFEIEKKLKEQ-- 973
Cdd:TIGR02168 567 QnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklrkalsylLGGvlvvddldNALELAKKLRPGyr 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 974 IVELQTKL------------NSELSALEKQKD-EKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAI 1040
Cdd:TIGR02168 647 IVTLDGDLvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1041 QTALDEFKLERELVEKELLEKV-----KHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKF------LEQLEEQEK 1109
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERiaqlsKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlkeeLKALREALD 806
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775931 1110 RKNEEMQNVRTSliAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:TIGR02168 807 ELRAELTLLNEE--AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
829-1093 |
1.48e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 829 SHASAIQEKEQQLQELKVKVSDLSDMRCKLEVEL--ALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLN 906
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEkaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 907 QKIHDNSESYQVGLSELrslmtiekdqcisELISRHEEESNILKAElDSVTALHhqAFEIEKKLKEQIVELQTKLNSELS 986
Cdd:COG4942 97 AELEAQKEELAELLRAL-------------YRLGRQPPLALLLSPE-DFLDAVR--RLQYLKYLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 987 ALEKQKDEKITQQEEKyKALIQNLEKDKQRLAMNhEQDKEQLIQKLNFEKdEAIQTALDEFKLErelvEKELLEKVKHLE 1066
Cdd:COG4942 161 ELAALRAELEAERAEL-EALLAELEEERAALEAL-KAERQKLLARLEKEL-AELAAELAELQQE----AEELEALIARLE 233
|
250 260
....*....|....*....|....*..
gi 1958775931 1067 NQIAkspafESAREDSSSLVAELQEKL 1093
Cdd:COG4942 234 AEAA-----AAAERTPAAGFAALKGKL 255
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
658-1110 |
2.42e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 59.08 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 658 ITLKEKHQQELQSLKIEYECKLNTLEKDSEEnvnKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLE 737
Cdd:pfam12128 271 ETLIASRQEERQETSAELNQLLRTLDDQWKE---KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 738 MENIMHTQNSEikelkqsremvLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHT------EEFEKVITDHKVS 811
Cdd:pfam12128 348 QLPSWQSELEN-----------LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDklakirEARDRQLAVAEDD 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 812 LEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDL---SDMRCKLEV-ELALKEAETDEIKILLEESRTQQKET- 886
Cdd:pfam12128 417 LQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAtatPELLLQLENfDERIERAREEQEAANAEVERLQSELRq 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 887 LKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMT-IEKD-----QCISELISRHEEESNILKAELDSVTA-- 958
Cdd:pfam12128 497 ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHfLRKEapdweQSIGKVISPELLHRTDLDPEVWDGSVgg 576
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 959 --------LHHQAFEI------EKKLKEQIVELQTKLNSELS---ALEKQ------KDEKITQQEEKYKALIQNLEKDKQ 1015
Cdd:pfam12128 577 elnlygvkLDLKRIDVpewaasEEELRERLDKAEEALQSAREkqaAAEEQlvqangELEKASREETFARTALKNARLDLR 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1016 RLAMNHEQDKEQLIQKLNFEKDEAIQ--TALDEFKLERELVEKELLEKVKH--LENQIAKSPAF---ESAREDSSSLVAE 1088
Cdd:pfam12128 657 RLFDEKQSEKDKKNKALAERKDSANErlNSLEAQLKQLDKKHQAWLEEQKEqkREARTEKQAYWqvvEGALDAQLALLKA 736
|
490 500
....*....|....*....|..
gi 1958775931 1089 LQEKLQEEKAKFLEQLEEQEKR 1110
Cdd:pfam12128 737 AIAARRSGAKAELKALETWYKR 758
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
694-1045 |
2.63e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 2.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 694 LKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLH------ 767
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEedlssl 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 768 DEKIESLRAEFQCLEQ---------NHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQ---QKIDQMLESHASAIQ 835
Cdd:TIGR02169 750 EQEIENVKSELKELEArieeleedlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 836 EKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINKLNQKIHDNS 913
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdLKKERDELEAQLRELERKIEELE 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 914 ESYQvglselrslmtiEKDQCISELisrhEEESNILKAELDSVTALHHQAFEI--EKKLKEQIVELQTKLNSELSALEKQ 991
Cdd:TIGR02169 910 AQIE------------KKRKRLSEL----KAKLEALEEELSEIEDPKGEDEEIpeEELSLEDVQAELQRVEEEIRALEPV 973
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1958775931 992 KDEKITQQEEKYKALiQNLEKDKQRLAMNHEQDKEqLIQKLNFEKDEAIQTALD 1045
Cdd:TIGR02169 974 NMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILE-RIEEYEKKKREVFMEAFE 1025
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
750-1047 |
6.05e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 6.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 750 KELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHlKELEDTLHIRHTEefekvITDHKVSLEKLKKEnQQKIDQMLES 829
Cdd:TIGR02168 220 AELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEK-----LEELRLEVSELEEE-IEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 830 HASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETENlrTEINKLNQKI 909
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL--EELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 910 HDNSESYQVGLSELRSlmtiekdqciseLISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNS----EL 985
Cdd:TIGR02168 371 ESRLEELEEQLETLRS------------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelkEL 438
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775931 986 SALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHE--QDKEQLIQKLNFEKD--EAIQTALDEF 1047
Cdd:TIGR02168 439 QAELEELEEELEELQEELERLEEALEELREELEEAEQalDAAERELAQLQARLDslERLQENLEGF 504
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
663-1122 |
8.24e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.11 E-value: 8.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 663 KHQQELQSL--KIEYEC-KLNTLEKDSEENVNKILKLKEDLVSlEEALQNKDSefaiiKHEKDaivcMQHEKDQKLLEME 739
Cdd:pfam01576 240 KKEEELQAAlaRLEEETaQKNNALKKIRELEAQISELQEDLES-ERAARNKAE-----KQRRD----LGEELEALKTELE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 740 NIMHTQNSEiKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELED-TLHIRHTEEFEKVITDHKVSLEKLKKE 818
Cdd:pfam01576 310 DTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEElTEQLEQAKRNKANLEKAKQALESENAE 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 819 NQQKIDQMLESHASAIQEK---EQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESrtqqketlksllEQET 895
Cdd:pfam01576 389 LQAELRTLQQAKQDSEHKRkklEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEA------------EGKN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 896 ENLRTEINKLNQKIHDNSESYQ----VGLSELRSLMTIEKDQciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLK 971
Cdd:pfam01576 457 IKLSKDVSSLESQLQDTQELLQeetrQKLNLSTRLRQLEDER--NSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 972 ------EQIVELQTKLNSELSALEKQKDEKITQQE--EKYKALIQN------LEKDKQR-LAMNHEQDKEQLIQKLNFEK 1036
Cdd:pfam01576 535 edagtlEALEEGKKRLQRELEALTQQLEEKAAAYDklEKTKNRLQQelddllVDLDHQRqLVSNLEKKQKKFDQMLAEEK 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1037 DEAIQTALDEFKLERELVEKE--LLEKVKHLENQIAKSPAFESAREdssSLVAELQEKL--QEEKAKFLEQLEEQEKRKN 1112
Cdd:pfam01576 615 AISARYAEERDRAEAEAREKEtrALSLARALEEALEAKEELERTNK---QLRAEMEDLVssKDDVGKNVHELERSKRALE 691
|
490
....*....|
gi 1958775931 1113 EEMQNVRTSL 1122
Cdd:pfam01576 692 QQVEEMKTQL 701
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
814-1171 |
1.73e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.84 E-value: 1.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 814 KLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAET---DEIKILLEESRTQQKETLKSL 890
Cdd:PRK03918 175 KRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVkelEELKEEIEELEKELESLEGSK 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 891 ---------LEQETENLRTEINKLNQKIHDNSE--SYQVGLSELRSLM--TIEKDQCISELISRHEEESNILKAELDSVT 957
Cdd:PRK03918 255 rkleekireLEERIEELKKEIEELEEKVKELKElkEKAEEYIKLSEFYeeYLDELREIEKRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 958 ALHHQAFEIEKKLKEqivelqtkLNSELSALEKQkdekiTQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKD 1037
Cdd:PRK03918 335 EKEERLEELKKKLKE--------LEKRLEELEER-----HELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1038 EaIQTALDEFKLER---ELVEKELLEKVKHLENQIAKSPAF--ESAREDSSSLVAELQEKLqEEKAKFLEQLEEQEKRKN 1112
Cdd:PRK03918 402 E-IEEEISKITARIgelKKEIKELKKAIEELKKAKGKCPVCgrELTEEHRKELLEEYTAEL-KRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1113 EEMQNVRTSLIAEQQtnfntvLTREKMRKENIINdLSDKLKS-TMQQQERDKDLIESLSE 1171
Cdd:PRK03918 480 KELRELEKVLKKESE------LIKLKELAEQLKE-LEEKLKKyNLEELEKKAEEYEKLKE 532
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
698-1172 |
3.45e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.97 E-value: 3.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 698 EDLVSLEEALQNKDSEFAIiKHEKDA----IVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREM-------VLEDLKKL 766
Cdd:TIGR00618 341 EEQRRLLQTLHSQEIHIRD-AHEVATsireISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIlqreqatIDTRTSAF 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 767 HDEKIESLRAEFQC-LEQNHLKELEdtLHIRHTEEFEKVITDHKVSLEKLKKENQQKI---DQMLESHASAIQEKEQQLQ 842
Cdd:TIGR00618 420 RDLQGQLAHAKKQQeLQQRYAELCA--AAITCTAQCEKLEKIHLQESAQSLKEREQQLqtkEQIHLQETRKKAVVLARLL 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 843 ELKVKVSDLsdmrCKLEVELALKEAETDEIKILleESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSE 922
Cdd:TIGR00618 498 ELQEEPCPL----CGSCIHPNPARQDIDNPGPL--TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 923 LRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKL----KEQIVELQTKLNS-ELSALEKQKDEKIT 997
Cdd:TIGR00618 572 FSIL---------TQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLaceqHALLRKLQPEQDLqDVRLHLQQCSQELA 642
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 998 QQEEKYKALIQNLEKDKQR--LAMNHEQDKEQLIQKLNFEKdeAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAF 1075
Cdd:TIGR00618 643 LKLTALHALQLTLTQERVRehALSIRVLPKELLASRQLALQ--KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1076 ESAREDSSSLVAELQ-------EKLQEEKAKFLEQLEEQEkrkNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDL 1148
Cdd:TIGR00618 721 NEIENASSSLGSDLAaredalnQSLKELMHQARTVLKART---EAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREED 797
|
490 500
....*....|....*....|....*.
gi 1958775931 1149 SDKLKSTMQQ--QERDKDLIESLSED 1172
Cdd:TIGR00618 798 THLLKTLEAEigQEIPSDEDILNLQC 823
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
806-1039 |
3.46e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 3.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 806 TDHKVSLEKLKKENQQKIDQM---LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAEtdeikilLEESRTQ 882
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELekeLAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-------LAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 883 QKEtlkslLEQETENLRTEINKLNQKIHDNSE--SYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALH 960
Cdd:COG4942 92 IAE-----LRAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 961 HQAFEIEKKLKEQIVELQTKLNsELSALEKQKDE---KITQQEEKYKALIQNLEKDKQRLamnheqdkEQLIQKLNFEKD 1037
Cdd:COG4942 167 AELEAERAELEALLAELEEERA-ALEALKAERQKllaRLEKELAELAAELAELQQEAEEL--------EALIARLEAEAA 237
|
..
gi 1958775931 1038 EA 1039
Cdd:COG4942 238 AA 239
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
657-1171 |
5.78e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.28 E-value: 5.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 657 EITLKEKHQQELQSLKIEYECKLNTLE---KDSEENVNKILKLKEDLVSL------------------EEALQNKDSEFA 715
Cdd:TIGR00606 225 QITSKEAQLESSREIVKSYENELDPLKnrlKEIEHNLSKIMKLDNEIKALksrkkqmekdnselelkmEKVFQGTDEQLN 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 716 IIKHEKDAIVcmqHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKL------HDEKIE---------SLRAEFQC 780
Cdd:TIGR00606 305 DLYHNHQRTV---REKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLqlqadrHQEHIRardsliqslATRLELDG 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 781 LEQNHLKELE----DTLHIRHTEEFEKVITDHKVSL---EKLKKENQQKIDQMLESHASAIQEK----EQQLQELKVKVS 849
Cdd:TIGR00606 382 FERGPFSERQiknfHTLVIERQEDEAKTAAQLCADLqskERLKQEQADEIRDEKKGLGRTIELKkeilEKKQEELKFVIK 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 850 DLSD----MRCKLEVELALKEAETDeIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHD-NSESYQVGLSELR 924
Cdd:TIGR00606 462 ELQQlegsSDRILELDQELRKAERE-LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQlNHHTTTRTQMEML 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 925 SLMTIEKDQCISELISRHEEESNILKAELDSVTALhHQAFEIEKKLKEQIVELQTKLNSELSALEKQKD------EKITQ 998
Cdd:TIGR00606 541 TKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL-EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNhinnelESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 999 QEEKYKALI------QNLEKDKQRLAMNHEQDKEQL-------------IQKLNFEKDEAIQTALDEFKLERELVE---- 1055
Cdd:TIGR00606 620 QLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRamlagatavysqfITQLTDENQSCCPVCQRVFQTEAELQEfisd 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1056 -----KELLEKVKHLENQIAKspafESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSlIAEQQTNF 1130
Cdd:TIGR00606 700 lqsklRLAPDKLKSTESELKK----KEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND-IEEQETLL 774
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 1958775931 1131 NTVLTREKMrKENIINDLSDKLKSTMQQQERDKDLIESLSE 1171
Cdd:TIGR00606 775 GTIMPEEES-AKVCLTDVTIMERFQMELKDVERKIAQQAAK 814
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
661-1056 |
5.80e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 54.14 E-value: 5.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 661 KEKHQQELQSLKiEYECKLNTLEKDSEenvNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMEN 740
Cdd:PRK01156 348 YDDLNNQILELE-GYEMDYNSYLKSIE---SLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 741 IMHTQNSEIKELKQSREMVLEDLKKLH-------------DEKIESLRAEFQcleqNHLKELEDtlHIRHTEEFEKVITD 807
Cdd:PRK01156 424 KVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttlgEEKSNHIINHYN----EKKSRLEE--KIREIEIEVKDIDE 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 808 HKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEvelALKEaETDEIKI-LLEESRTQQKET 886
Cdd:PRK01156 498 KIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYE---EIKN-RYKSLKLeDLDSKRTSWLNA 573
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 887 LKSLLEQETENLRTEINKLNQKIHDNSEsyqvGLSELRSlmTIEKDQC-ISELISRHEEESNILKAELDSVTALHHQAFE 965
Cdd:PRK01156 574 LAVISLIDIETNRSRSNEIKKQLNDLES----RLQEIEI--GFPDDKSyIDKSIREIENEANNLNNKYNEIQENKILIEK 647
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 966 IEKK---LKEQIVELQTKLNSelsalEKQKDEKITQQEEKYKAL---IQNLEKDKQRLAMNHE---QDKEQLIQKLN--- 1033
Cdd:PRK01156 648 LRGKidnYKKQIAEIDSIIPD-----LKEITSRINDIEDNLKKSrkaLDDAKANRARLESTIEilrTRINELSDRINdin 722
|
410 420
....*....|....*....|....*
gi 1958775931 1034 --FEKDEAIQTALDEFKLERELVEK 1056
Cdd:PRK01156 723 etLESMKKIKKAIGDLKRLREAFDK 747
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
649-1340 |
5.93e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.21 E-value: 5.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 649 IDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKI----LKLKEDLVSLEEALQNKDSEFAIIKHEKD-- 722
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKaleyYQLKEKLELEEEYLLYLDYLKLNEERIDLlq 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 723 ---AIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNH-LKELEDTLHIRHT 798
Cdd:pfam02463 244 ellRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKvDDEEKLKESEKEK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 799 EEFEKVITDHKVS---LEKLKKE-------NQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAE 868
Cdd:pfam02463 324 KKAEKELKKEKEEieeLEKELKEleikreaEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 869 TDEIKILLEESRTQ----QKETLKSLLEQETENLRTEINKLNQKIHDNSESYQV------GLSELRSLMTIEKDQCISEL 938
Cdd:pfam02463 404 EKEAQLLLELARQLedllKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkllkdELELKKSEDLLKETQLVKLQ 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 939 ISR------------------HEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQT--KLNSELSALEKQKDEKITQ 998
Cdd:pfam02463 484 EQLelllsrqkleersqkeskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKvaISTAVIVEVSATADEVEER 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 999 QEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLN--------------FEKDEAIQTALDEFKLERELVEKELLEKVKH 1064
Cdd:pfam02463 564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlaqldkatLEADEDDKRAKVVEGILKDTELTKLKESAKA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1065 LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQ-------------------------LEEQEKRKNEEMQNVR 1119
Cdd:pfam02463 644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQekaeselakeeilrrqleikkkeqrEKEELKKLKLEAEELL 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1120 TSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRTSSVLPSA 1199
Cdd:pfam02463 724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1200 PVLAAPELYGACAPELPGEPERSAMETTDEGRVDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEEN-KRLNQRLMS 1278
Cdd:pfam02463 804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLlKEEELEEQK 883
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 1279 QSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGE 1340
Cdd:pfam02463 884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
694-1163 |
8.35e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 8.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 694 LKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDekies 773
Cdd:pfam05483 215 FKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE----- 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 774 lraefqclEQNHL-KELEDTlhirhteefeKVITDHKVSLEKLKKENQQ----KIDQMLESHASAIQEKEQQLQELKVKV 848
Cdd:pfam05483 290 --------KKDHLtKELEDI----------KMSLQRSMSTQKALEEDLQiatkTICQLTEEKEAQMEELNKAKAAHSFVV 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 849 SDLSDMRCKLE----VELALKEAETDEIKILLEE-----SRTQQKETLKSLLEQETENLRTEINKlNQKIHDNSESYQVG 919
Cdd:pfam05483 352 TEFEATTCSLEellrTEQQRLEKNEDQLKIITMElqkksSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 920 LSELRSlmtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKlNSELSA------------ 987
Cdd:pfam05483 431 AEELKG-----KEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK-NIELTAhcdklllenkel 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 988 ----------LEKQKDEKIT--QQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQ-----KLNFEKDEAIQTALDEFKLE 1050
Cdd:pfam05483 505 tqeasdmtleLKKHQEDIINckKQEERMLKQIENLEEKEMNLRDELESVREEFIQkgdevKCKLDKSEENARSIEYEVLK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1051 RELVEKELLEKVKHLENQIA-KSPAFESAREDSSSL-----VAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA 1124
Cdd:pfam05483 585 KEKQMKILENKCNNLKKQIEnKNKNIEELHQENKALkkkgsAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIE 664
|
490 500 510
....*....|....*....|....*....|....*....
gi 1958775931 1125 EQQTNFNTVLtrEKMRKENIINDLSDKLKSTMQQQERDK 1163
Cdd:pfam05483 665 DKKISEEKLL--EEVEKAKAIADEAVKLQKEIDKRCQHK 701
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
834-1127 |
9.50e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 9.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 834 IQEKEQQLQELKVKVSDLSDMRCKLEVELALKEaetdEIKILLEESR-TQQKETLKSL--LEQETENLRTEINKLNQKIh 910
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLRREREKAE----RYQALLKEKReYEGYELLKEKeaLERQKEAIERQLASLEEEL- 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 911 dnsESYQVGLSELRSLMTiEKDQCISELISR----HEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQ---TKLNS 983
Cdd:TIGR02169 254 ---EKLTEEISELEKRLE-EIEQLLEELNKKikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEerlAKLEA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 984 ELSALEKQK---DEKITQQEEKYKALIQNLEKDKQRLAmnheqDKEQLIQklnfEKDEAIQTALDEFKLERELVEK---- 1056
Cdd:TIGR02169 330 EIDKLLAEIeelEREIEEERKRRDKLTEEYAELKEELE-----DLRAELE----EVDKEFAETRDELKDYREKLEKlkre 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1057 ----------------ELLEKVKHLENQIA----KSPAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQ 1116
Cdd:TIGR02169 401 inelkreldrlqeelqRLSEELADLNAAIAgieaKINELEEEKEDKALEIKKQEWKLEQLAAD-LSKYEQELYDLKEEYD 479
|
330
....*....|.
gi 1958775931 1117 NVRTSLIAEQQ 1127
Cdd:TIGR02169 480 RVEKELSKLQR 490
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
832-1043 |
1.12e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 52.52 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 832 SAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHD 911
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK-----LQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 912 NSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALhhqafeieKKLKEQIVELQTKLNSELSALEKQ 991
Cdd:COG3883 91 RARALYRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEEL--------KADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775931 992 KDEKITQQEE------KYKALIQNLEKDKQRLamnhEQDKEQLIQKLNFEKDEAIQTA 1043
Cdd:COG3883 163 KAELEAAKAEleaqqaEQEALLAQLSAEEAAA----EAQLAELEAELAAAEAAAAAAA 216
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
672-1172 |
1.14e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.61 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 672 KIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiIKHEKDAIVCMQHEKDQKlleMENIMHTQNSEIKE 751
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE---AKKKADAAKKKAEEAKKA---AEAAKAEAEAAADE 1358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 752 LKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLH--IRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLES 829
Cdd:PTZ00121 1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEedKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK 1438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 830 HAsaiqEKEQQLQELKVKVSDlsdmrcKLEVELALKEAE----TDEIKILLEESRTQQKetlkslLEQETENLRTEINKL 905
Cdd:PTZ00121 1439 KA----EEAKKADEAKKKAEE------AKKAEEAKKKAEeakkADEAKKKAEEAKKADE------AKKKAEEAKKKADEA 1502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 906 NQKIHDNSESYQVGLSELRSlmtiEKDQCISELISRHEEESNilKAELDSVTALHHQAFEIEKKLKEQIVElQTKLNSEL 985
Cdd:PTZ00121 1503 KKAAEAKKKADEAKKAEEAK----KADEAKKAEEAKKADEAK--KAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEED 1575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 986 SALEKQKDEKITQQEEKYKALIQNL-EKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKlERELVEKELLEKVKH 1064
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEARIEEVMKLyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK-KKEAEEKKKAEELKK 1654
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1065 LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQL--EEQEKRKNEEMQNVRtsliAEQqtnfntVLTREKMRKE 1142
Cdd:PTZ00121 1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkEAEEAKKAEELKKKE----AEE------KKKAEELKKA 1724
|
490 500 510
....*....|....*....|....*....|
gi 1958775931 1143 NIINDLsdKLKSTMQQQERDKDLIESLSED 1172
Cdd:PTZ00121 1725 EEENKI--KAEEAKKEAEEDKKKAEEAKKD 1752
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
655-1104 |
1.23e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.12 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 655 SLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQK 734
Cdd:PRK02224 306 DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 735 LLEMEnimhtqnSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHKVSLEK 814
Cdd:PRK02224 386 IEELE-------EEIEELRERFGDAPVDLGNAEDFL-EELREERDELRER-EAELEATL-----RTARERVEEAEALLEA 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 815 LK-KENQQKIDQmlESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVEL----ALKEAET-----DEIKILLEESRTQQK 884
Cdd:PRK02224 452 GKcPECGQPVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLeraeDLVEAEDrierlEERREDLEELIAERR 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 885 ETLKSLLEQeTENLRTEINKLNQKIHDNSESYQvglsELRSlmtiEKDQCISElISRHEEESNILKAELDSVTALHHQAF 964
Cdd:PRK02224 530 ETIEEKRER-AEELRERAAELEAEAEEKREAAA----EAEE----EAEEAREE-VAELNSKLAELKERIESLERIRTLLA 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 965 EIEkKLKEQIVELQTKLnSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNfEKDEAIQTAL 1044
Cdd:PRK02224 600 AIA-DAEDEIERLREKR-EALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVE-EKLDELREER 676
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775931 1045 DEFK-----LERELVE-KELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQL 1104
Cdd:PRK02224 677 DDLQaeigaVENELEElEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRNVETLERM 742
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
749-1175 |
1.75e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.73 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 749 IKELKQSREMVLEDLKKLHDEKIE-SLRAEFQCLEQNhLKELEDTLH---------IRHTEEFEKVITDHKVSLEKLKkE 818
Cdd:PRK02224 178 VERVLSDQRGSLDQLKAQIEEKEEkDLHERLNGLESE-LAELDEEIEryeeqreqaRETRDEADEVLEEHEERREELE-T 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 819 NQQKIDQMLESHASAIQEKE---QQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQ-- 893
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREelaEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrv 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 894 -------ETENLRTEINKL---NQKIHDNSESYQVGLSELRSLMTIEKDQcISEL---ISRHEEESNILKAELDSVTALH 960
Cdd:PRK02224 336 aaqahneEAESLREDADDLeerAEELREEAAELESELEEAREAVEDRREE-IEELeeeIEELRERFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 961 HQAFEIEKKLKEQIVELQTKLNSELSALEKQKD----EKITQ--QEEKYKALIQNLEKDKQRLAmNHEQDKEQLIQKLNf 1034
Cdd:PRK02224 415 EELREERDELREREAELEATLRTARERVEEAEAlleaGKCPEcgQPVEGSPHVETIEEDRERVE-ELEAELEDLEEEVE- 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1035 EKDEAIQTALDEFKLERELveKELLEKVKHLENQIA--------KSPAFESAREDSSSLVAELQEK------LQEEKAKF 1100
Cdd:PRK02224 493 EVEERLERAEDLVEAEDRI--ERLEERREDLEELIAerretieeKRERAEELRERAAELEAEAEEKreaaaeAEEEAEEA 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1101 LEQLEEQEKRKN------EEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS-DKLKStmqQQERDKDL-------- 1165
Cdd:PRK02224 571 REEVAELNSKLAelkeriESLERIRTLLAAIADAEDEIERLREKREALAELNDERrERLAE---KRERKRELeaefdear 647
|
490
....*....|
gi 1958775931 1166 IESLSEDRAR 1175
Cdd:PRK02224 648 IEEAREDKER 657
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
642-1277 |
1.97e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 642 AVEIRNIIDKVKCSLEITLKEKHQQElQSLKIEYECKLNTLEKDSEEnvnkiLKLKEDLVSLEEALQNKDSEFAIIKHEK 721
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKAEEARKAE-DAKKAEAVKKAEEAKKDAEE-----AKKAEEERNNEEIRKFEEARMAHFARRQ 1269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 722 DAIVCMQHEKDQKLLEMENImhtqnSEIKELKQSREM-VLEDLKKLHDEKieslraefqcleqnhlkeledtlhiRHTEE 800
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEK-----KKADEAKKAEEKkKADEAKKKAEEA-------------------------KKADE 1319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 801 FEKVITDHKVSLEKLKK--ENQQKIDQMLESHASAIQEKEQQLQElKVKVSDLSDMRCKLEVELALKEAE----TDEIKI 874
Cdd:PTZ00121 1320 AKKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEE-KAEAAEKKKEEAKKKADAAKKKAEekkkADEAKK 1398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 875 LLEESRTQQKETLKSLLEQ----ETENLRTEINKLNQKIHDNSESYQVglSELRSlmTIEKDQCISELISRHEEESNILK 950
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKkkadEAKKKAEEKKKADEAKKKAEEAKKA--DEAKK--KAEEAKKAEEAKKKAEEAKKADE 1474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 951 A-----ELDSVTALHHQAFEIEKKLKE--QIVELQTKLNSELSALEKQKDEKITQQEEKYKA-------LIQNLEKDKQR 1016
Cdd:PTZ00121 1475 AkkkaeEAKKADEAKKKAEEAKKKADEakKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAdeakkaeEKKKADELKKA 1554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1017 LAMNHEQDKEQLIQKLNFEKDEAIQTALDEfklERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEE 1096
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1097 KAKF--LEQLEEQEKRKNEEMQNvrtsliAEQQtnfNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRA 1174
Cdd:PTZ00121 1632 KKKVeqLKKKEAEEKKKAEELKK------AEEE---NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1175 RLLEEKKKLEEEVSKlrtssvlpSAPVLAAPELYGACAPELPGEPERSAmETTDEGRVDSAMETSMMsvQENMLSEEKQR 1254
Cdd:PTZ00121 1703 KAEELKKKEAEEKKK--------AEELKKAEEENKIKAEEAKKEAEEDK-KKAEEAKKDEEEKKKIA--HLKKEEEKKAE 1771
|
650 660
....*....|....*....|...
gi 1958775931 1255 IMLLERTLQLKEEENKRLNQRLM 1277
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRRM 1794
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
653-1172 |
2.01e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 52.44 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 653 KCSLEITLKEKHQQELQ--SLKIEYECKLNTLEKDSEENVNK-------ILKLKEDLVSLEEALQNKDSEFAIIKHEKDA 723
Cdd:pfam05557 8 KARLSQLQNEKKQMELEhkRARIELEKKASALKRQLDRESDRnqelqkrIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 724 IVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMvledlkklHDEKIESLRAEFQCLEQNHlkeleDTLHIRHTeEFEK 803
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQR--------AELELQSTNSELEELQERL-----DLLKAKAS-EAEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 804 VITDHKVSLEKLKKENQ--QKIDQMLESHASAIQEKEQQLQELkVKVSDLSDMRCKLEVELAlKEAETDEIKILLEEsrt 881
Cdd:pfam05557 154 LRQNLEKQQSSLAEAEQriKELEFEIQSQEQDSEIVKNSKSEL-ARIPELEKELERLREHNK-HLNENIENKLLLKE--- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 882 qQKETLKSLLEQETE------NLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDqcISELISR---HEEESNILKAE 952
Cdd:pfam05557 229 -EVEDLKRKLEREEKyreeaaTLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRR--IEQLQQReivLKEENSSLTSS 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 953 LDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKI--TQQEEKYKALIQNLEKDkqrLAM-NHEQDK---- 1025
Cdd:pfam05557 306 ARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLllTKERDGYRAILESYDKE---LTMsNYSPQLleri 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1026 ---EQLIQKLNfEKDEAIQTALDefKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAkfle 1102
Cdd:pfam05557 383 eeaEDMTQKMQ-AHNEEMEAQLS--VAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEVDSLRRKLETLEL---- 455
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958775931 1103 QLEEQEKRKNE-EMQNVRTSLiaeqQTNFNTVLTREKMRKENIINDLSDKLKSTMQQ----QERDKDLIESLSED 1172
Cdd:pfam05557 456 ERQRLREQKNElEMELERRCL----QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKlqaeIERLKRLLKKLEDD 526
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
968-1274 |
2.14e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 2.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 968 KKLKEQIVELQ--------TKLNSELSALEKQKDEKiTQQEEKYKALIQNLEKDKQ--RLAMNHEQDKEQLIQKLNFEKD 1037
Cdd:TIGR02168 216 KELKAELRELElallvlrlEELREELEELQEELKEA-EEELEELTAELQELEEKLEelRLEVSELEEEIEELQKELYALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1038 EAIQtaldefKLERELVEKEllEKVKHLENQIAKSPA----FESAREDSSSLVAELQEKLQEEKAKFlEQLEEQEKRKNE 1113
Cdd:TIGR02168 295 NEIS------RLEQQKQILR--ERLANLERQLEELEAqleeLESKLDELAEELAELEEKLEELKEEL-ESLEAELEELEA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1114 EMQNvRTSLIAEQQTNFNTVltrekmRKEniINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEekkkleeevsklRTS 1193
Cdd:TIGR02168 366 ELEE-LESRLEELEEQLETL------RSK--VAQLELQIASLNNEIERLEARLERLEDRRERLQQ------------EIE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1194 SVLPSAPVLAAPELYGACAPELPGEPERSAMETTDEGRVDSAME-----TSMMSVQENMLSEEKQRIMLLERTLQLKEEE 1268
Cdd:TIGR02168 425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREeleeaEQALDAAERELAQLQARLDSLERLQENLEGF 504
|
....*.
gi 1958775931 1269 NKRLNQ 1274
Cdd:TIGR02168 505 SEGVKA 510
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
661-1116 |
3.24e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 661 KEKHQQELQSLKiEYECKLNTLEKDSEENVNKILKLKEDLVSLEEA---LQNKDSEFAIIKHEKDAIVCMQHEKDQKLLE 737
Cdd:pfam01576 18 KERQQKAESELK-ELEKKHQQLCEEKNALQEQLQAETELCAEAEEMrarLAARKQELEEILHELESRLEEEEERSQQLQN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 738 MENIMHTQNSEIKELKQSREMVLEDL---KKLHDEKIESLRAEFQCLE------QNHLKELEDTLH---IRHTEEFEKVI 805
Cdd:pfam01576 97 EKKKMQQHIQDLEEQLDEEEAARQKLqleKVTTEAKIKKLEEDILLLEdqnsklSKERKLLEERISeftSNLAEEEEKAK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 806 TDHKVSL----------EKLKKENQQKidQMLESHASAIQEKEQQLQElkvKVSDLSDMRCKLEVELALKEAETDEIKIL 875
Cdd:pfam01576 177 SLSKLKNkheamisdleERLKKEEKGR--QELEKAKRKLEGESTDLQE---QIAELQAQIAELRAQLAKKEEELQAALAR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 876 LEESRTQQKETLKSL---------LEQETENLRTEINKLNQKIHDNSESYQVGLSELRSlmTIEKDQCISELISRHEEES 946
Cdd:pfam01576 252 LEEETAQKNNALKKIreleaqiseLQEDLESERAARNKAEKQRRDLGEELEALKTELED--TLDTTAAQQELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 947 NILKAELDSVTALHH-QAFEIEKKLKEQIVELQTKLnsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDK 1025
Cdd:pfam01576 330 TELKKALEEETRSHEaQLQEMRQKHTQALEELTEQL--EQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKR 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1026 EQLIQKLNfekdeAIQTALDEFKLERElvekELLEKVKHLENQI---------AKSPAFESAREDSS--SLVAELQEKLQ 1094
Cdd:pfam01576 408 KKLEGQLQ-----ELQARLSESERQRA----ELAEKLSKLQSELesvssllneAEGKNIKLSKDVSSleSQLQDTQELLQ 478
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 1958775931 1095 EE-----------------KAKFLEQLEEQ-EKRKNEEMQ 1116
Cdd:pfam01576 479 EEtrqklnlstrlrqledeRNSLQEQLEEEeEAKRNVERQ 518
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
696-1104 |
3.32e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 51.76 E-value: 3.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 696 LKEDLVSLEEALQnkdSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTqnseikeLKQSREmvleDLKKLHDEKiESLR 775
Cdd:pfam12128 602 LRERLDKAEEALQ---SAREKQAAAEEQLVQANGELEKASREETFARTA-------LKNARL----DLRRLFDEK-QSEK 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 776 AEFQcleqnhlkeledtlhiRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQE-KEQQLQELKVKVSDLSDM 854
Cdd:pfam12128 667 DKKN----------------KALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREaRTEKQAYWQVVEGALDAQ 730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 855 RCKLEVELALKEAETD-EIKILleesRTQQKETLKSL--LEQETENLRTEINKLNQKIhdnsESYQVGLSELRSLMTIEK 931
Cdd:pfam12128 731 LALLKAAIAARRSGAKaELKAL----ETWYKRDLASLgvDPDVIAKLKREIRTLERKI----ERIAVRRQEVLRYFDWYQ 802
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 932 DQCISELISRHEEESNILKAELDsvtalhhqaFEIEKKLKEQIVELQ-TKLNSELSALEKQKDEkITQQEEKYKALIQnl 1010
Cdd:pfam12128 803 ETWLQRRPRLATQLSNIERAISE---------LQQQLARLIADTKLRrAKLEMERKASEKQQVR-LSENLRGLRCEMS-- 870
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1011 ekdkqRLAMNHE-QDKEQLIQKLNFEKDeaiqtALDEFKLERELVEKELLEKVKHLENQIAKSPA------FESAREDSS 1083
Cdd:pfam12128 871 -----KLATLKEdANSEQAQGSIGERLA-----QLEDLKLKRDYLSESVKKYVEHFKNVIADHSGsglaetWESLREEDH 940
|
410 420
....*....|....*....|..
gi 1958775931 1084 SLVAELQEKLQEEK-AKFLEQL 1104
Cdd:pfam12128 941 YQNDKGIRLLDYRKlVPYLEQW 962
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
739-1172 |
4.05e-06 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 51.76 E-value: 4.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 739 ENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFqcleqNHLKELEDTLHIRH-TEEFEKVITDHKVSLEKLKK 817
Cdd:PTZ00440 420 EDVLKENSQKIADYALYSNLEIIEIKKKYDEKINELKKSI-----NQLKTLISIMKSFYdLIISEKDSMDSKEKKESSDS 494
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 818 ENQQKIDQML------ESHASAIQEKEQQLQELKVKVSDLsdmrcKLEVELALKEAETDEIKILLEESRTQQKETLKSLL 891
Cdd:PTZ00440 495 NYQEKVDELLqiinsiKEKNNIVNNNFKNIEDYYITIEGL-----KNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDI 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 892 EQETENLRTEINKLNQKIHDNSESYQV--GLSELRSLMTIEKDQCISELISRHEEESNI--------LKAELDSVTAL-- 959
Cdd:PTZ00440 570 KNKIKYIEENVDHIKDIISLNDEIDNIiqQIEELINEALFNKEKFINEKNDLQEKVKYIlnkfykgdLQELLDELSHFld 649
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 960 HHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLA-MNHEQDKEQLIQKLN--FEK 1036
Cdd:PTZ00440 650 DHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIDNIIKNLKKELQNLLSLKENIIkKQLNNIEQDISNSLNqyTIK 729
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1037 DEAIQTALDEFKlerelVEKELLEKVKHLENQIakspafesaredssslvaelqeklqeeKAKFLEQLEEQEKR------ 1110
Cdd:PTZ00440 730 YNDLKSSIEEYK-----EEEEKLEVYKHQIINR---------------------------KNEFILHLYENDKDlpdgkn 777
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775931 1111 -KNEEMQNVRTSLIAEQQTNFNTVLTRE--KMRKENI--INDLSDKLKS-TMQQQERDKDLIESLSED 1172
Cdd:PTZ00440 778 tYEEFLQYKDTILNKENKISNDINILKEnkKNNQDLLnsYNILIQKLEAhTEKNDEELKQLLQKFPTE 845
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
730-1122 |
6.10e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 6.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 730 EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhdEKIESLRAEFQCLEQ--NHLKELEDTLhiRHTEEFEKVITD 807
Cdd:COG4717 85 EKEEEYAELQEELEELEEELEELEAELEELREELEKL--EKLLQLLPLYQELEAleAELAELPERL--EELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 808 HKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKilleesrtQQKETL 887
Cdd:COG4717 161 LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE--------EELEQL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 888 KSLLEQEtenlrteinKLNQKIHDNSESYqVGLSELRSLMTIekdqcISELISRHEEESNILKA----------ELDSVT 957
Cdd:COG4717 233 ENELEAA---------ALEERLKEARLLL-LIAAALLALLGL-----GGSLLSLILTIAGVLFLvlgllallflLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 958 ALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKIT------QQEEKYKALIQNLEKDKQRLAMN-HEQDKEQLIQ 1030
Cdd:COG4717 298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEellellDRIEELQELLREAEELEEELQLEeLEQEIAALLA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1031 KLNFEKDEAIQTALDEFKLERelvekELLEKVKHLENQIAKSPAFESAREDSSSLvAELQEKLQEEKAKfLEQLEEQEKR 1110
Cdd:COG4717 378 EAGVEDEEELRAALEQAEEYQ-----ELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEE-LEELEEELEE 450
|
410
....*....|..
gi 1958775931 1111 KNEEMQNVRTSL 1122
Cdd:COG4717 451 LREELAELEAEL 462
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
666-1074 |
6.25e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.89 E-value: 6.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 666 QELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiiKHEKDAIvcmQHEKDQKLLEMEnimhtQ 745
Cdd:pfam17380 247 EDVTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKAVSERQQQEKFE----KMEQERL---RQEKEEKAREVE-----R 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 746 NSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKvSLEKLKKENQQK--- 822
Cdd:pfam17380 315 RRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMR-ELERLQMERQQKner 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 823 IDQMLES-HASAIQEKEQQLQELKVKVsdlsdmrcklevelalkeaETDEIKILLEESRTQQKETLKSLLEQETENLRTE 901
Cdd:pfam17380 394 VRQELEAaRKVKILEEERQRKIQQQKV-------------------EMEQIRAEQEEARQREVRRLEEERAREMERVRLE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 902 INKLNQKIhdnsesyqvglselrslmtiekdqcisELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKl 981
Cdd:pfam17380 455 EQERQQQV---------------------------ERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQ- 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 982 nselSALEKQKDEKITQQE--EKYKALIQnlekDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELL 1059
Cdd:pfam17380 507 ----AMIEEERKRKLLEKEmeERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMM 578
|
410
....*....|....*
gi 1958775931 1060 EKVKHLENQIAKSPA 1074
Cdd:pfam17380 579 RQIVESEKARAEYEA 593
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
662-1128 |
6.94e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 50.85 E-value: 6.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 662 EKHQQELQSLKIEYEcKLNTLEKDSEENVNKILKLKEDLVSLE----EALQNKDSEFAIIKHEKDAIVcmQHEKDQKLLE 737
Cdd:COG5022 878 ELAERQLQELKIDVK-SISSLKLVNLELESEIIELKKSLSSDLienlEFKTELIARLKKLLNNIDLEE--GPSIEYVKLP 954
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 738 MENIMHTQNSEIKELKQSREMVLEDLKKLHDEKI----ESLR-----AEFQCLE---QNHLKELEDTLHI--RHTEEFEK 803
Cdd:COG5022 955 ELNKLHEVESKLKETSEEYEDLLKKSTILVREGNkansELKNfkkelAELSKQYgalQESTKQLKELPVEvaELQSASKI 1034
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 804 VITDHKvSLEKLKKENQQKIDQMLEshasaIQEKEQQLQELKVKVSDLSDMRCKLE----VELALKEAETDEIKILLEES 879
Cdd:COG5022 1035 ISSEST-ELSILKPLQKLKGLLLLE-----NNQLQARYKALKLRRENSLLDDKQLYqlesTENLLKTINVKDLEVTNRNL 1108
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 880 RTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTAL 959
Cdd:COG5022 1109 VKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALY 1188
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 960 ---HHQAFEIEKKLKEQIVELQTKLNSELSALEKQKD---EKITQQEEKYK---ALIQNLEKDKQRlamnhEQDKEQLIQ 1030
Cdd:COG5022 1189 dekSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKlisEGWVPTEYSTSlkgFNNLNKKFDTPA-----SMSNEKLLS 1263
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1031 KLNfekdeaiqtaLDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAkfleqlEEQEKR 1110
Cdd:COG5022 1264 LLN----------SIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSE------ELDDWC 1327
|
490
....*....|....*...
gi 1958775931 1111 KNEEMQNVRTSLIAEQQT 1128
Cdd:COG5022 1328 REFEISDVDEELEELIQA 1345
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
639-1054 |
7.08e-06 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 50.34 E-value: 7.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 639 KCTAVEIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIK 718
Cdd:COG5185 143 LDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 719 HEKDAIVCMQH--EKDQKLLEMENIMHTQNSEIKE-LKQSREMVLEDLK------KLHDEKIESLRAEFQCLEQNhLKEL 789
Cdd:COG5185 223 EKAKEIINIEEalKGFQDPESELEDLAQTSDKLEKlVEQNTDLRLEKLGenaessKRLNENANNLIKQFENTKEK-IAEY 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 790 EDTLHIR-HTEEFEKVI--TDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDmrcklEVELALKE 866
Cdd:COG5185 302 TKSIDIKkATESLEEQLaaAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-----EVELSKSS 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 867 AETDEIKILLEESRTQQKETLKSLLEQETENLRTEINklNQKIHDNSESyqvglselrslmtiEKDQCISELISRHEEES 946
Cdd:COG5185 377 EELDSFKDTIESTKESLDEIPQNQRGYAQEILATLED--TLKAADRQIE--------------ELQRQIEQATSSNEEVS 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 947 NILKAELDSVTALHHqafEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKE 1026
Cdd:COG5185 441 KLLNELISELNKVMR---EADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRS 517
|
410 420
....*....|....*....|....*...
gi 1958775931 1027 QLIQKLNFEKDEAIQTALDEFKLERELV 1054
Cdd:COG5185 518 KLDQVAESLKDFMRARGYAHILALENLI 545
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
656-1175 |
7.23e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.81 E-value: 7.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 656 LEITLKEKHQQELQSLKIEYECKLNTLEKD---SEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDaivcmqhEKD 732
Cdd:PRK02224 192 LKAQIEEKEEKDLHERLNGLESELAELDEEierYEEQREQARETRDEADEVLEEHEERREELETLEAEIE-------DLR 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 733 QKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEkieslrAEFQCLEQNHLKELEDTLHIRHtEEFEKVITDHKVSL 812
Cdd:PRK02224 265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAE------AGLDDADAEAVEARREELEDRD-EELRDRLEECRVAA 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 813 EKLKKE---NQQKIDQmLESHASAIQEK----EQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEES---RTQ 882
Cdd:PRK02224 338 QAHNEEaesLREDADD-LEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAedfLEE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 883 QKETLKSLLEQETEnLRTEINKLNQKIHDNSESYQVG--------LSELRSLMTIEKDQcisELISRHEEESNILKAELD 954
Cdd:PRK02224 417 LREERDELREREAE-LEATLRTARERVEEAEALLEAGkcpecgqpVEGSPHVETIEEDR---ERVEELEAELEDLEEEVE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 955 SVTALHHQAfeieKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKAlIQNLEKDKQRLAMNHEQdKEQLIQKLNF 1034
Cdd:PRK02224 493 EVEERLERA----EDLVEAEDRIERLEE-RREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEE-KREAAAEAEE 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1035 EKDEAIQTALDefkLERELVE-KELLEKVKHLENQIAkspafesAREDSSSLVAELQEKLQEekakfLEQLEEQEKRKNE 1113
Cdd:PRK02224 566 EAEEAREEVAE---LNSKLAElKERIESLERIRTLLA-------AIADAEDEIERLREKREA-----LAELNDERRERLA 630
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 1114 EMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLkstmqqqerdkdliESLSEDRAR 1175
Cdd:PRK02224 631 EKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKL--------------DELREERDD 678
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
654-1017 |
1.16e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 654 CSLEITlkEKHQQELQSlkiEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALqnkdsefaiikhekdaivcmqhEKDQ 733
Cdd:PRK03918 441 CGRELT--EEHRKELLE---EYTAELKRIEKELKEIEEKERKLRKELRELEKVL----------------------KKES 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 734 KLLEMENIMhtqnSEIKELKQSREMV-LEDLKKlHDEKIESLRAEFQCLEQNhLKELEDTLhiRHTEEFEKVITDHKVSL 812
Cdd:PRK03918 494 ELIKLKELA----EQLKELEEKLKKYnLEELEK-KAEEYEKLKEKLIKLKGE-IKSLKKEL--EKLEELKKKLAELEKKL 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 813 EKLKKENQQKIDQMLESHASAIQEKEQQLQEL-------------KVKVSDLSDMRCKLEVELALKEAETDEIKILLEES 879
Cdd:PRK03918 566 DELEEELAELLKELEELGFESVEELEERLKELepfyneylelkdaEKELEREEKELKKLEEELDKAFEELAETEKRLEEL 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 880 RTQQKETLKSLLEQETENLRTEINKLNQKIhdnsESYQVGLSELRSLM-----TIEKDQCISELISRHEEESNILKAELD 954
Cdd:PRK03918 646 RKELEELEKKYSEEEYEELREEYLELSREL----AGLRAELEELEKRReeikkTLEKLKEELEEREKAKKELEKLEKALE 721
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958775931 955 SVTALHHQAFEIEKKLKEQIVELQTKLNSELSalekqkdEKITqqEEKYKALIQNLEKDKQRL 1017
Cdd:PRK03918 722 RVEELREKVKKYKALLKERALSKVGEIASEIF-------EELT--EGKYSGVRVKAEENKVKL 775
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
878-1128 |
1.17e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.44 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 878 ESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciselisrhEEESNILKAELDSVT 957
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEAL----------------QAEIDKLQAEIAEAE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 958 AlhhqafEIEKK---LKEQIVELQTK--LNSELSALEKQKD--------EKITQQEEKYKALIQNLEKDKQRLamnhEQD 1024
Cdd:COG3883 79 A------EIEERreeLGERARALYRSggSVSYLDVLLGSESfsdfldrlSALSKIADADADLLEELKADKAEL----EAK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1025 KEQLIQKLNfekdeaiqtaldefklERELVEKELLEKVKHLENQIAKspafesaREDSSSLVAELQEKLQEEKAKFLEQL 1104
Cdd:COG3883 149 KAELEAKLA----------------ELEALKAELEAAKAELEAQQAE-------QEALLAQLSAEEAAAEAQLAELEAEL 205
|
250 260
....*....|....*....|....
gi 1958775931 1105 EEQEKRKNEEMQNVRTSLIAEQQT 1128
Cdd:COG3883 206 AAAEAAAAAAAAAAAAAAAAAAAA 229
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
958-1113 |
1.24e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.00 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 958 ALHHQAFEIEKKLKE---QIVELQTKLNSELSALEKQKDEKitqqeEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNF 1034
Cdd:COG1579 14 ELDSELDRLEHRLKElpaELAELEDELAALEARLEAAKTEL-----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958775931 1035 EKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:COG1579 89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
820-1173 |
2.65e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 48.66 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 820 QQKIDQMLEShasaIQEKEQQLQELKVKVSDLSDMRCKLEVELA-LKEAETDEIKILleESRTQQKETLKSLLEQETENL 898
Cdd:pfam10174 400 QKKIENLQEQ----LRDKDKQLAGLKERVKSLQTDSSNTDTALTtLEEALSEKERII--ERLKEQREREDRERLEELESL 473
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 899 RTEINKLNQKihdnsesyqvgLSELRSLMTiEKDQCISELisrHEEESNILKAELDSVTALHHQAFEIEKKlKEQIVELQ 978
Cdd:pfam10174 474 KKENKDLKEK-----------VSALQPELT-EKESSLIDL---KEHASSLASSGLKKDSKLKSLEIAVEQK-KEECSKLE 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 979 TKLnselsaLEKQKDEKITQQEEKYKALIQNLEKDKQRLAmnHEQDKEQliqklnfEKDEAIQTALDEFKLERELVEKEL 1058
Cdd:pfam10174 538 NQL------KKAHNAEEAVRTNPEINDRIRLLEQEVARYK--EESGKAQ-------AEVERLLGILREVENEKNDKDKKI 602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1059 LEKVKHLENQIakspafesarEDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEqqtnfnTVLTREK 1138
Cdd:pfam10174 603 AELESLTLRQM----------KEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEE------LMGALEK 666
|
330 340 350
....*....|....*....|....*....|....*.
gi 1958775931 1139 MRKEniINDLSDKLKSTMQQ-QERDKDLiESLSEDR 1173
Cdd:pfam10174 667 TRQE--LDATKARLSSTQQSlAEKDGHL-TNLRAER 699
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
730-1172 |
3.25e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.43 E-value: 3.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 730 EKDQKLLEMEnimhtqnsEIKELKQSREMVLEDLKKLHDeKIESLRAEFQCLEQnhlkeledtlhirHTEEFEKVITDHK 809
Cdd:TIGR00618 164 EKKELLMNLF--------PLDQYTQLALMEFAKKKSLHG-KAELLTLRSQLLTL-------------CTPCMPDTYHERK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 810 VSLEKLKKENQQKIDQMLESHASAIQEKEQQ---------LQELKVKVSDLSDMRCKLE-----VELALKEAETDEIKIL 875
Cdd:TIGR00618 222 QVLEKELKHLREALQQTQQSHAYLTQKREAQeeqlkkqqlLKQLRARIEELRAQEAVLEetqerINRARKAAPLAAHIKA 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 876 LEESRTQQKETLKSLleQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEkdqcisELISRHEEESNILKAELDS 955
Cdd:TIGR00618 302 VTQIEQQAQRIHTEL--QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE------IHIRDAHEVATSIREISCQ 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 956 VTALHHQAfeieKKLKEQIVELQTKLNSelsalekQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFE 1035
Cdd:TIGR00618 374 QHTLTQHI----HTLQQQKTTLTQKLQS-------LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAEL 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1036 KDEAIQTALDEFKLeRELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAkfleQLEEQEKRKNEEM 1115
Cdd:TIGR00618 443 CAAAITCTAQCEKL-EKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPC----PLCGSCIHPNPAR 517
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775931 1116 QNvrtSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR00618 518 QD---IDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
876-1125 |
3.25e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 3.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 876 LEESRTQQK-ETLKSL------LEQETENLRTEINKLnQKIHDNSESYQVGLSELRSLmtiekDQCISEL-ISRHEEESN 947
Cdd:COG4913 218 LEEPDTFEAaDALVEHfddlerAHEALEDAREQIELL-EPIRELAERYAAARERLAEL-----EYLRAALrLWFAQRRLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 948 ILKAELDSVTALHHQAFEIEKKLKEQIVELQTklnsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQdkeq 1027
Cdd:COG4913 292 LLEAELEELRAELARLEAELERLEARLDALRE----ELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR---- 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1028 liqklnfekdeaIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESA-REDSSSLVAELQEkLQEEKAKFLEQLEE 1106
Cdd:COG4913 364 ------------LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEAlEEALAEAEAALRD-LRRELRELEAEIAS 430
|
250 260
....*....|....*....|..
gi 1958775931 1107 QEKRKN---EEMQNVRTSLIAE 1125
Cdd:COG4913 431 LERRKSnipARLLALRDALAEA 452
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
698-1110 |
4.32e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.97 E-value: 4.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 698 EDLVSLEEALQNKDSEFAIIKHEKDAIVcMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEsLRAE 777
Cdd:pfam07888 4 DELVTLEEESHGEEGGTDMLLVVPRAEL-LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRE-LESR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 778 FQCLEQN--HLKELEDTLHIRHTEE--FEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQ---EKEQQLQELKVKVSD 850
Cdd:pfam07888 82 VAELKEElrQSREKHEELEEKYKELsaSSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQrvlERETELERMKERAKK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 851 LSDMRCKLEVElalKEAETDEIKILLEESRTQQKE--TLKSLLEQ---ETENLRTEINKLNQKI---HDNSESYQVGLSE 922
Cdd:pfam07888 162 AGAQRKEEEAE---RKQLQAKLQQTEEELRSLSKEfqELRNSLAQrdtQVLQLQDTITTLTQKLttaHRKEAENEALLEE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 923 LRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALekqKDEKITQQEEK 1002
Cdd:pfam07888 239 LRSL---------QERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLAL---REGRARWAQER 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1003 yKALIQNLEKDKQRlamnheqdkeqlIQKLNFEKdEAIQTALDEFKLERELVEKELLEKVKhlENQIAKSPAFESAREDS 1082
Cdd:pfam07888 307 -ETLQQSAEADKDR------------IEKLSAEL-QRLEERLQEERMEREKLEVELGREKD--CNRVQLSESRRELQELK 370
|
410 420 430
....*....|....*....|....*....|
gi 1958775931 1083 SSLVAELQEK--LQEEKAKFLEQLEEQEKR 1110
Cdd:pfam07888 371 ASLRVAQKEKeqLQAEKQELLEYIRQLEQR 400
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
879-1175 |
5.47e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.81 E-value: 5.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 879 SRTQQKETLKSLleqETENLRTEinkLNQKIHDNSESYQVGLSELRSLMTIEKDQCIselISRHEEESNILKAELDSVTa 958
Cdd:pfam17380 285 SERQQQEKFEKM---EQERLRQE---KEEKAREVERRRKLEEAEKARQAEMDRQAAI---YAEQERMAMERERELERIR- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 959 LHHQAFEIEKKLKEQI-VELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKD 1037
Cdd:pfam17380 355 QEERKRELERIRQEEIaMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1038 EAIQTALDEFKLERELVEKELLEKVKHLEnQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQN 1117
Cdd:pfam17380 435 REVRRLEEERAREMERVRLEEQERQQQVE-RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEER 513
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775931 1118 VRTSLIAEQQTNFNTVLTREKMRKEniinDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:pfam17380 514 KRKLLEKEMEERQKAIYEEERRREA----EEERRKQQEMEERRRIQEQMRKATEERSR 567
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
651-1151 |
5.59e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 48.12 E-value: 5.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 651 KVKCSLEITLKEKHQQELQS-LKIEYECKLN------TLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIK----- 718
Cdd:TIGR01612 525 IIGFDIDQNIKAKLYKEIEAgLKESYELAKNwkklihEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINklkle 604
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 719 -HEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKEL-KQSREMVLEDLKKlHDEKIESLRAEFQCLEQNHLKELEDTLH-- 794
Cdd:TIGR01612 605 lKEKIKNISDKNEYIKKAIDLKKIIENNNAYIDELaKISPYQVPEHLKN-KDKIYSTIKSELSKIYEDDIDALYNELSsi 683
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 795 -----IRHTEEFEKvITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVkvsdlsDMRCKLEVELalkeaeT 869
Cdd:TIGR01612 684 vkenaIDNTEDKAK-LDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIV------EIKKHIHGEI------N 750
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 870 DEIKILLEESRTQQKETLKSLLEQETENlrTEINKLNQKI-----HDNSESYQVGLSELRSLMTIEKDQCISELISRHEE 944
Cdd:TIGR01612 751 KDLNKILEDFKNKEKELSNKINDYAKEK--DELNKYKSKIseiknHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKED 828
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 945 ES----NILKAELDSVTALHHQAFEIEKKLKEQI-------VELQTKLNSELSalekqkDEKITQQEEKY---KALIQNL 1010
Cdd:TIGR01612 829 EIfkiiNEMKFMKDDFLNKVDKFINFENNCKEKIdseheqfAELTNKIKAEIS------DDKLNDYEKKFndsKSLINEI 902
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1011 EKdkqrlAMNHEQDKEQLIQKLN--FEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSsslvae 1088
Cdd:TIGR01612 903 NK-----SIEEEYQNINTLKKVDeyIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNT------ 971
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958775931 1089 LQEKLQEEKAKFLE-QLEEQEKRKNEEMQNVrTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1151
Cdd:TIGR01612 972 LIDKINELDKAFKDaSLNDYEAKNNELIKYF-NDLKANLGKNKENMLYHQFDEKEKATNDIEQK 1034
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
660-908 |
5.71e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 5.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 660 LKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEME 739
Cdd:TIGR04523 423 LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 740 NIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEslraefqclEQNHLKELEDTLHirhTEEFEKvitdHKVSLEKLKKEN 819
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLKEKIEKLESEKKE---------KESKISDLEDELN---KDDFEL----KKENLEKEIDEK 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 820 QQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESR--TQQKETLKSL---LEQE 894
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEklSSIIKNIKSKknkLKQE 646
|
250
....*....|....
gi 1958775931 895 TENLRTEINKLNQK 908
Cdd:TIGR04523 647 VKQIKETIKEIRNK 660
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
795-1145 |
6.40e-05 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 47.63 E-value: 6.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 795 IRHTEEFEKVITDhKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQelkVKVSDLSDMRCKLEVELALKEAETDEIKi 874
Cdd:pfam15818 24 TQYEEQIGKIIVE-TQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQ---MKMCALEEEKGKYQLATEIKEKEIEGLK- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 875 lleesrtqqkETLKSLlEQETENLRTEINKLNQKIHDN---SESYQVGLSELRSLMT----------------------- 928
Cdd:pfam15818 99 ----------ETLKAL-QVSKYSLQKKVSEMEQKLQLHllaKEDHHKQLNEIEKYYAtitgqfglvkenhgkleqnvqea 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 929 IEKDQCISELISRHEEESNILKAELDSVTA--------LHHQAFE--IEKKLKEQ-IVELQTKLNSELsALEKQKDEKIT 997
Cdd:pfam15818 168 IQLNKRLSALNKKQESEICSLKKELKKVTSdlikskvtCQYKMGEenINLTIKEQkFQELQERLNMEL-ELNKKINEEIT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 998 Q-QEEKYKALI--QNLEKDKQRLAM-NHEQDKEQLIQKLNFekdeaiQTALDEFKLERELVeKELLEKVKHLENQ----- 1068
Cdd:pfam15818 247 HiQEEKQDIIIsfQHMQQLLQQQTQaNTEMEAELKALKENN------QTLERDNELQREKV-KENEEKFLNLQNEhekal 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1069 -IAKSPAFESARE-----DSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVrtsliaeqqTNFNTVLTREKMrkE 1142
Cdd:pfam15818 320 gTWKKHVEELNGEineikNELSSLKETHIKLQEHYNKLCNQKKFEEDKKFQNVPEV---------NNENSEMSTEKS--E 388
|
...
gi 1958775931 1143 NII 1145
Cdd:pfam15818 389 NLI 391
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
966-1163 |
6.47e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 6.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 966 IEKKLKEQIVELQTK-------LNSELSALEKQKDEkITQQEEKYKALIQNLEKDKQRLAMNhEQDKEQLIQKLNF-EKD 1037
Cdd:COG4717 47 LLERLEKEADELFKPqgrkpelNLKELKELEEELKE-AEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKlEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1038 EAIQTALDEFK-LERELveKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1116
Cdd:COG4717 125 LQLLPLYQELEaLEAEL--AELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1958775931 1117 NVRTSlIAEQQTNFNTvLTREKMRKENIINDLSDKLKSTMQQQERDK 1163
Cdd:COG4717 203 ELQQR-LAELEEELEE-AQEELEELEEELEQLENELEAAALEERLKE 247
|
|
| MAP65_ASE1 |
pfam03999 |
Microtubule associated protein (MAP65/ASE1 family); |
727-955 |
9.42e-05 |
|
Microtubule associated protein (MAP65/ASE1 family);
Pssm-ID: 427641 [Multi-domain] Cd Length: 477 Bit Score: 46.53 E-value: 9.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 727 MQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLED--------------LKKLHDEKiESLRAEFQCLEQNHLKELEDt 792
Cdd:pfam03999 102 LRKEKAPRLAEIKELLEQLQQLCEELGEEPLPLLIDplpsleelesfrkhLENLRNEK-ERRLEEVNELKKQIKLLMEE- 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 793 LHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDmrcKLEVELALKEAETDEI 872
Cdd:pfam03999 180 LDLVPGTDFEEDLLCESEDNFCLSRENIDKLRKLIKQLEEQKAEREEKIDDLREKILELWN---RLQVPQEEQESFVREN 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 873 KILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAE 952
Cdd:pfam03999 257 NSLSQDTIDALREELQRLEELKKKNIKKLIEDLRVEIEELWDKLFYSTEQRKRFIPFFEELYTEDLLELHELELKRLKEE 336
|
...
gi 1958775931 953 LDS 955
Cdd:pfam03999 337 YES 339
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
756-992 |
9.60e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 9.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 756 REMVLEDlKKLHDEkIESLRAEFQCLEQNH-----LKELEDTL-HIR-HTEEFEKVITDHKVsLEKLKKENQQKIDQ-ML 827
Cdd:COG4913 214 REYMLEE-PDTFEA-ADALVEHFDDLERAHealedAREQIELLePIReLAERYAAARERLAE-LEYLRAALRLWFAQrRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 828 ESHASAIQEKEQQLQELKVKVSDLsdmrcklEVELALKEAETDEIKILLEESRTQQKETLksllEQETENLRTEINKLNQ 907
Cdd:COG4913 291 ELLEAELEELRAELARLEAELERL-------EARLDALREELDELEAQIRGNGGDRLEQL----EREIERLERELEERER 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 908 KihdnSESYQVGLSELR-SLMTIEKDqcISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQtklnSELS 986
Cdd:COG4913 360 R----RARLEALLAALGlPLPASAEE--FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE----AEIA 429
|
....*.
gi 1958775931 987 ALEKQK 992
Cdd:COG4913 430 SLERRK 435
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
616-1192 |
9.75e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 47.35 E-value: 9.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 616 IKDDLCH--FRTFVQKEQCDLSNYLKCTAVEIRNIIDKVkcsleitlkEKHQQELQSLKI-------EYECKLNTLEKDS 686
Cdd:TIGR01612 1089 IKEKLKHynFDDFGKEENIKYADEINKIKDDIKNLDQKI---------DHHIKALEEIKKksenyidEIKAQINDLEDVA 1159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 687 E-----ENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIvcmqhEKDQKLLE-MENIMHTQNSEIKELKQSRemvL 760
Cdd:TIGR01612 1160 DkaisnDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEI-----EKDKTSLEeVKGINLSYGKNLGKLFLEK---I 1231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 761 EDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKenQQKIDQMLESHASAIQEKEQQ 840
Cdd:TIGR01612 1232 DEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKD--HHIISKKHDENISDIREKSLK 1309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 841 LQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRT---------------QQKETLKSLlEQETENLRTEINK- 904
Cdd:TIGR01612 1310 IIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANiynilklnkikkiidEVKEYTKEI-EENNKNIKDELDKs 1388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 905 --LNQKIHDNSeSYQVGLSELRSLMtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLN 982
Cdd:TIGR01612 1389 ekLIKKIKDDI-NLEECKSKIESTL---DDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADN 1464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 983 SELSALEKQKDEKITQQEEKYKALIQNLEK--------DKQRLAMNH-----EQDKEQLIQKLNFEKDEAIQTALDEFKL 1049
Cdd:TIGR01612 1465 KSQHILKIKKDNATNDHDFNINELKEHIDKskgckdeaDKNAKAIEKnkelfEQYKKDVTELLNKYSALAIKNKFAKTKK 1544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1050 ERELVEKEllekVKHLENQIakspafesaredssSLVAELQE----KLQEEKAKFLEQLEEQEKrKNEEMQNVRTSL--- 1122
Cdd:TIGR01612 1545 DSEIIIKE----IKDAHKKF--------------ILEAEKSEqkikEIKKEKFRIEDDAAKNDK-SNKAAIDIQLSLenf 1605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1123 ------IAEQQTNFNTVLTREKMRKENI----INDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRT 1192
Cdd:TIGR01612 1606 enkflkISDIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEK 1685
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
592-1277 |
1.04e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.89 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 592 RAALHVQLEKCRVaaQDSHISIQTIKDDLCHFRTFVQKEQCDLSNYL-KCTAVEIRNIIDKVKCSLEITLKEKHQQ---- 666
Cdd:TIGR00618 202 RSQLLTLCTPCMP--DTYHERKQVLEKELKHLREALQQTQQSHAYLTqKREAQEEQLKKQQLLKQLRARIEELRAQeavl 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 667 ELQSLKIEYECKLNTLEKDSEenvnKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIV------CMQHEKDQKLLEMEN 740
Cdd:TIGR00618 280 EETQERINRARKAAPLAAHIK----AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVkqqssiEEQRRLLQTLHSQEI 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 741 IMHTQNSEIKELKQSREMVLEDLKKLH--DEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKlKKE 818
Cdd:TIGR00618 356 HIRDAHEVATSIREISCQQHTLTQHIHtlQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK-QQE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 819 NQQKIDQMLESHAsaiqekEQQLQELKVKVSDLSDMRCKLEvelALKEAETDEIKILLEESRTQQKETLKSLLEQETENL 898
Cdd:TIGR00618 435 LQQRYAELCAAAI------TCTAQCEKLEKIHLQESAQSLK---EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCP 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 899 RTEinklnQKIHDNSESYQVGLS------------ELRSLMTIEKD---QCISEL--ISRHEEESNILKAELDSVTALHH 961
Cdd:TIGR00618 506 LCG-----SCIHPNPARQDIDNPgpltrrmqrgeqTYAQLETSEEDvyhQLTSERkqRASLKEQMQEIQQSFSILTQCDN 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 962 QAFEIEKKLKEQIVELQtKLNSELSALEKQKDEKITQQEEKykaliQNLEKDKQRLAMnHEQDKEQLIQKLNFEKdEAIQ 1041
Cdd:TIGR00618 581 RSKEDIPNLQNITVRLQ-DLTEKLSEAEDMLACEQHALLRK-----LQPEQDLQDVRL-HLQQCSQELALKLTAL-HALQ 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1042 TALDEFKLERELVEKELLEKVKHLENQiAKSPAFESAREDSSSLVAELQEKLqeEKAKFLEQLEEQEKRKNEEMQNVRTS 1121
Cdd:TIGR00618 653 LTLTQERVREHALSIRVLPKELLASRQ-LALQKMQSEKEQLTYWKEMLAQCQ--TLLRELETHIEEYDREFNEIENASSS 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1122 LIAEQQTNFNTVltrekmrkENIINDLSDKLKSTMQQQERD---KDLIESLSEDRARLLEEKKKLEEEVSKLRTSSVLPS 1198
Cdd:TIGR00618 730 LGSDLAAREDAL--------NQSLKELMHQARTVLKARTEAhfnNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLL 801
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958775931 1199 APVLAAPELYgacAPElpGEPERSAMETTDEGRVDsametsmmsvQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLM 1277
Cdd:TIGR00618 802 KTLEAEIGQE---IPS--DEDILNLQCETLVQEEE----------QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLT 865
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
657-869 |
1.23e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 657 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAivcMQHEKDQKLL 736
Cdd:COG4942 35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA---QKEELAELLR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 737 EMEniMHTQNSEIKELKQS--------REMVLEDLKKLHDEKIESLRAEfqcleQNHLKELEDTLHiRHTEEFEKVITDH 808
Cdd:COG4942 112 ALY--RLGRQPPLALLLSPedfldavrRLQYLKYLAPARREQAEELRAD-----LAELAALRAELE-AERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958775931 809 KVSLEKLKKENQQKiDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAET 869
Cdd:COG4942 184 EEERAALEALKAER-QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
730-908 |
1.24e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 730 EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHK 809
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-ERRIAALARRIRALEQE-LAALEAEL-----AELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 810 VSLEKLKKE---------------------NQQKIDQ---MLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALK 865
Cdd:COG4942 97 AELEAQKEElaellralyrlgrqpplalllSPEDFLDavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1958775931 866 EAETDEIKIL---LEESRTQQKETLKSlLEQETENLRTEINKLNQK 908
Cdd:COG4942 177 EALLAELEEEraaLEALKAERQKLLAR-LEKELAELAAELAELQQE 221
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
810-1131 |
1.25e-04 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 46.39 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 810 VSLEKLKKENQQKidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLeVELALKEAetdeIKILLEESRTQQKETLKS 889
Cdd:PLN03229 411 VPVDPERKVNMKK----REAVKTPVRELEGEVEKLKEQILKAKESSSKP-SELALNEM----IEKLKKEIDLEYTEAVIA 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 890 L-LEQETENLRTEINKLN-----------QKIHDNSESYQVGLSE----------LRSLMTIEKDQCISELISRHE---- 943
Cdd:PLN03229 482 MgLQERLENLREEFSKANsqdqlmhpvlmEKIEKLKDEFNKRLSRapnylslkykLDMLNEFSRAKALSEKKSKAEklka 561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 944 ----------------EESNILKAELDSVTAlhHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALI 1007
Cdd:PLN03229 562 einkkfkevmdrpeikEKMEALKAEVASSGA--SSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDTA 639
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1008 QnlEKDKQRLAMNHEQDKEQLIQKL-NFEKDEAIQTALDEFKLERELVEK----ELLEKVKHLENQIAKSPAfesAREDS 1082
Cdd:PLN03229 640 E--QTPPPNLQEKIESLNEEINKKIeRVIRSSDLKSKIELLKLEVAKASKtpdvTEKEKIEALEQQIKQKIA---EALNS 714
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1958775931 1083 SSLvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFN 1131
Cdd:PLN03229 715 SEL-KEKFEELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRVEVN 762
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
812-1175 |
1.48e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 812 LEKLKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDM---------RCKLEVELALKEAETDEIKILLEESRTQ 882
Cdd:COG4717 83 AEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKLlqllplyqeLEALEAELAELPERLEELEERLEELREL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 883 QKEtlKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQcISELISRHEEESNILKAELDSVTALhHQ 962
Cdd:COG4717 162 EEE--LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE-LEEELEEAQEELEELEEELEQLENE-LE 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 963 AFEIEKKLKEQIVELqtKLNSELSALEKQKDEKITQQEEKYKAL--------IQNLEKDKQRLAMNHEQDKEQLIQKLNF 1034
Cdd:COG4717 238 AAALEERLKEARLLL--LIAAALLALLGLGGSLLSLILTIAGVLflvlgllaLLFLLLAREKASLGKEAEELQALPALEE 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1035 EKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDS--SSLVAELQEKLQEEKAKFLEQLEEQEKRKN 1112
Cdd:COG4717 316 LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAALEQAE 395
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958775931 1113 EEMQNVRTSLIAEQQTNFNTVLTREKMRKENiINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:COG4717 396 EYQELKEELEELEEQLEELLGELEELLEALD-EEELEEELEELEEELEELEEELEELREELAE 457
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
866-1191 |
1.75e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 866 EAETDEIKILLeeSRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESyqvgLSELRSLmtIEKDQCISELISRHEEE 945
Cdd:PRK03918 175 KRRIERLEKFI--KRTENIEELIKEKEKELEEVLREINEISSELPELREE----LEKLEKE--VKELEELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 946 SNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLnSELSALEKQKDEKITQQE--EKYKALIQNLEKDKQRLAmnheq 1023
Cdd:PRK03918 247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV-KELKELKEKAEEYIKLSEfyEEYLDELREIEKRLSRLE----- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1024 dkeqliqklnfEKDEAIQTALDEF-KLERELveKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQ----EKLQEEKA 1098
Cdd:PRK03918 321 -----------EEINGIEERIKELeEKEERL--EELKKKLKELEKRLEELEERHELYEEAKAKKEELErlkkRLTGLTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1099 KFLEQLEEQEKRKnEEMQNVRTSLIAEQqtnfNTVLTREKMRKENIINDLSDKLKSTMQQQERD----KDLIESLSEDRA 1174
Cdd:PRK03918 388 KLEKELEELEKAK-EEIEEEISKITARI----GELKKEIKELKKAIEELKKAKGKCPVCGRELTeehrKELLEEYTAELK 462
|
330
....*....|....*..
gi 1958775931 1175 RLLEEKKKLEEEVSKLR 1191
Cdd:PRK03918 463 RIEKELKEIEEKERKLR 479
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
683-1113 |
2.09e-04 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 46.09 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 683 EKDSEENVNKILKLKEDLVSLEEALQNKDSefAIIKHEKDAIVCMQHEKDQKL--LEMENIMHTQNSEIKElkQSREMVL 760
Cdd:pfam15818 23 ETQYEEQIGKIIVETQELKWQKETLQNQKE--TLAKQHKEAMAVFKKQLQMKMcaLEEEKGKYQLATEIKE--KEIEGLK 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 761 EDLKKLHDEKIeSLRAEFQCLEQN---HLKELEDtlHIRHTEEFEK---VITDH----KVSLEKLKKENQQKIDqmLESH 830
Cdd:pfam15818 99 ETLKALQVSKY-SLQKKVSEMEQKlqlHLLAKED--HHKQLNEIEKyyaTITGQfglvKENHGKLEQNVQEAIQ--LNKR 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 831 ASAIQEKEQQ-----LQELKVKVSDLsdMRCKLEVELALKEaetDEIKILLEESRTQQKetlkslleQETENLRTEIN-K 904
Cdd:pfam15818 174 LSALNKKQESeicslKKELKKVTSDL--IKSKVTCQYKMGE---ENINLTIKEQKFQEL--------QERLNMELELNkK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 905 LNQKIHDNSESYQVGLSELrslmtiekdQCISELISRHEEESNILKAELdsvtalhhqafeieKKLKEQivelqtklNSE 984
Cdd:pfam15818 241 INEEITHIQEEKQDIIISF---------QHMQQLLQQQTQANTEMEAEL--------------KALKEN--------NQT 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 985 LSALEKQKDEKITQQEEKYkaliQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLER---ELVEKELLEK 1061
Cdd:pfam15818 290 LERDNELQREKVKENEEKF----LNLQNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEhynKLCNQKKFEE 365
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775931 1062 VKHLEN-QIAKSPAFESAREDSSSLVAE----LQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:pfam15818 366 DKKFQNvPEVNNENSEMSTEKSENLIIQkynsEQEIREENTKSFCSDTEYRETEKKK 422
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
629-1169 |
2.32e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 45.98 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 629 KEQCDLSNYLKCTavEIRNIIDKVKcsleitlkeKHQQELQSLKIEY-ECKLNTLEKDSEENVNKILKLKEDLVSLEEAL 707
Cdd:PTZ00440 672 KNEYEKLEFMKSD--NIDNIIKNLK---------KELQNLLSLKENIiKKQLNNIEQDISNSLNQYTIKYNDLKSSIEEY 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 708 QNKDSEFAIIKHE----KDAIVCMQHEKDQKLLEMENIM-----HTQNSEIKELKQSREMV-LEDLKKLHDEKIESLRAE 777
Cdd:PTZ00440 741 KEEEEKLEVYKHQiinrKNEFILHLYENDKDLPDGKNTYeeflqYKDTILNKENKISNDINiLKENKKNNQDLLNSYNIL 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 778 FQCLEQNHLKELEDTLHIRHTEEfEKVITDHKVSLEKLKKENQQKIDQMLEShasaIQEKEQQLQELK-VKVSDLSDMRC 856
Cdd:PTZ00440 821 IQKLEAHTEKNDEELKQLLQKFP-TEDENLNLKELEKEFNENNQIVDNIIKD----IENMNKNINIIKtLNIAINRSNSN 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 857 KLEVElALKEAETDEIKILleESRTQQKETLKSLLEQETENLRTEINKLNQKIhdNSESYQVGLSELRslMTIEKdqcis 936
Cdd:PTZ00440 896 KQLVE-HLLNNKIDLKNKL--EQHMKIINTDNIIQKNEKLNLLNNLNKEKEKI--EKQLSDTKINNLK--MQIEK----- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 937 eLISRHEEesniLKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQR 1016
Cdd:PTZ00440 964 -TLEYYDK----SKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKQHDDIIELIDKLIKEKGK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1017 lamNHEQDKEQLIQKLNFEKD--EAIQTALDEFKLERELVE---KELLEKVKHLENQIAKSP-AFESAREDSSSLVAEL- 1089
Cdd:PTZ00440 1039 ---EIEEKVDQYISLLEKMKTklSSFHFNIDIKKYKNPKIKeeiKLLEEKVEALLKKIDENKnKLIEIKNKSHEHVVNAd 1115
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1090 -----QEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNfNTVLTREKMRKENIINDLSDKLKSTMQQQERDKD 1164
Cdd:PTZ00440 1116 keknkQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLNEVN-EIEIEYERILIDHIVEQINNEAKKSKTIMEEIES 1194
|
....*
gi 1958775931 1165 LIESL 1169
Cdd:PTZ00440 1195 YKKDI 1199
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
943-1080 |
2.39e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 2.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 943 EEESNILK--AELDSVTALHHQAFEIEKKLKEQIVELQTK----------LNSELSALEKqKDEKITQQEEKYKALIQNL 1010
Cdd:PRK12704 48 KKEAEAIKkeALLEAKEEIHKLRNEFEKELRERRNELQKLekrllqkeenLDRKLELLEK-REEELEKKEKELEQKQQEL 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1011 EKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDefKLERELvEKELLEKVKHLENQiAKSPAFESARE 1080
Cdd:PRK12704 127 EKKEEELEELIEEQLQELERISGLTAEEAKEILLE--KVEEEA-RHEAAVLIKEIEEE-AKEEADKKAKE 192
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
747-914 |
3.02e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.15 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 747 SEIKELKQSREMVLEDLKK----LHDEKIESLRAEFQCLEQNHLKELEDTLhiRHTEEFEKVITDHKVSLEKlKKENQQK 822
Cdd:PRK12704 31 AKIKEAEEEAKRILEEAKKeaeaIKKEALLEAKEEIHKLRNEFEKELRERR--NELQKLEKRLLQKEENLDR-KLELLEK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 823 IDQMLESHASAIQEKEQQLQELKVKvsdlsdmrcklevelaLKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEI 902
Cdd:PRK12704 108 REEELEKKEKELEQKQQELEKKEEE----------------LEELIEEQLQELERISGLTAEEAKEILLEKVEEEARHEA 171
|
170
....*....|..
gi 1958775931 903 NKLNQKIHDNSE 914
Cdd:PRK12704 172 AVLIKEIEEEAK 183
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
656-1118 |
3.16e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 3.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 656 LEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEkdaivcmQHEKDQKL 735
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE-------LLEALRAA 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 736 LEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEfqclEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKL 815
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE----EEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 816 KKENQQKIDQMLESHASAIQEKEQQLQELK--------VKVSDLSDMRCKL--------EVELALKEAETDEIKILLEES 879
Cdd:COG1196 472 AALLEAALAELLEELAEAAARLLLLLEAEAdyegflegVKAALLLAGLRGLagavavliGVEAAYEAALEAALAAALQNI 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 880 RTQQKETLKSLLEQETENLRTEINKL-NQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILkAELDSVTA 958
Cdd:COG1196 552 VVEDDEVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL-LGRTLVAA 630
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 959 LHHQAFEIEKKLKEQ--IVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQliqklnfek 1036
Cdd:COG1196 631 RLEAALRRAVTLAGRlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA--------- 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1037 dEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1116
Cdd:COG1196 702 -EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
|
..
gi 1958775931 1117 NV 1118
Cdd:COG1196 781 PV 782
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
645-910 |
3.99e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 45.00 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 645 IRNIIDKVKCSLEitlKEKHQQ------ELQSLKIEYECKLNTLEKDSEENVNKILK---------LKEDLVSLEEALQN 709
Cdd:NF033838 67 LEKILSEIQKSLD---KRKHTQnvalnkKLSDIKTEYLYELNVLKEKSEAELTSKTKkeldaafeqFKKDTLEPGKKVAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 710 KDSEFAIIKHEKDAivcmQHEKDQ--------KLLEMEnimhTQNSEIKELKQSREMVLEDLKKLHDE--------KIES 773
Cdd:NF033838 144 ATKKVEEAEKKAKD----QKEEDRrnyptntyKTLELE----IAESDVEVKKAELELVKEEAKEPRDEekikqakaKVES 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 774 LRAEFQCLEQ--NHLKELEDTLHIRHTEEFEKVITDHKVSLEKL------------------KKENQQKI------DQML 827
Cdd:NF033838 216 KKAEATRLEKikTDREKAEEEAKRRADAKLKEAVEKNVATSEQDkpkrrakrgvlgepatpdKKENDAKSsdssvgEETL 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 828 ESHA----SAIQEKEQQLQELKVKVSDL--SDMRC-------KLEVELA-----LKEAETDEIKILLEESRT-----QQK 884
Cdd:NF033838 296 PSPSlkpeKKVAEAEKKVEEAKKKAKDQkeEDRRNyptntykTLELEIAesdvkVKEAELELVKEEAKEPRNeekikQAK 375
|
330 340
....*....|....*....|....*...
gi 1958775931 885 ETLKSLLEQET--ENLRTEINKLNQKIH 910
Cdd:NF033838 376 AKVESKKAEATrlEKIKTDRKKAEEEAK 403
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
627-899 |
4.04e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.10 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 627 VQKEQCDLSNYLKCTAVEIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLntlekdseenvnkilkLKEDLVSLEEA 706
Cdd:pfam05483 539 LEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI----------------LENKCNNLKKQ 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 707 LQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKK-LHDEKIEslraefqclEQNH 785
Cdd:pfam05483 603 IENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKeIEDKKIS---------EEKL 673
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 786 LKELEDTlhirhteefeKVITDHKVSLEK-LKKENQQKIDQM---LESHA----SAIQEKEQQLQELKVKVSDLSDMRCK 857
Cdd:pfam05483 674 LEEVEKA----------KAIADEAVKLQKeIDKRCQHKIAEMvalMEKHKhqydKIIEERDSELGLYKNKEQEQSSAKAA 743
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1958775931 858 LEVELALKEAETDEIKILLEESRtQQKETLKSLLEQETENLR 899
Cdd:pfam05483 744 LEIELSNIKAELLSLKKQLEIEK-EEKEKLKMEAKENTAILK 784
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
575-906 |
4.70e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 4.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 575 SRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDLCHFRTFVQKEQCDLSnYLKCTAVEIRNIIDKVKC 654
Cdd:TIGR02169 708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIE-ELEEDLHKLEEALNDLEA 786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 655 SLEITLKEKHQQELQSLKiEYECKLNTLEKDSEENVNKILKLKEdlvSLEEALQNKDSEFAIIKHEKDAIVCMQH----- 729
Cdd:TIGR02169 787 RLSHSRIPEIQAELSKLE-EEVSRIEARLREIEQKLNRLTLEKE---YLEKEIQELQEQRIDLKEQIKSIEKEIEnlngk 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 730 --EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQnHLKELEDTLHIRHTEEFE----- 802
Cdd:TIGR02169 863 keELEEELEELEAALRDLESRLGDLKKERDELEAQLREL-ERKIEELEAQIEKKRK-RLSELKAKLEALEEELSEiedpk 940
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 803 ---KVITDHKVSLEKLKKEnQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLevelalkEAETDEIKILLEES 879
Cdd:TIGR02169 941 gedEEIPEEELSLEDVQAE-LQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKL-------EEERKAILERIEEY 1012
|
330 340
....*....|....*....|....*..
gi 1958775931 880 RTQQKETLKSLLEQETENLRTEINKLN 906
Cdd:TIGR02169 1013 EKKKREVFMEAFEAINENFNEIFAELS 1039
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
963-1120 |
5.09e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 44.43 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 963 AFEIEKKL----------KEQIVELQTKLN---SELSALEKQKDEKITQQEEkykaLIQNLEKDKQRLamnheqdkEQLI 1029
Cdd:PRK00409 490 AFEIAKRLglpeniieeaKKLIGEDKEKLNeliASLEELERELEQKAEEAEA----LLKEAEKLKEEL--------EEKK 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1030 QKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREdssslvaelqekLQEEKAKFLEQLEEQEK 1109
Cdd:PRK00409 558 EKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHE------------LIEARKRLNKANEKKEK 625
|
170
....*....|.
gi 1958775931 1110 RKNEEMQNVRT 1120
Cdd:PRK00409 626 KKKKQKEKQEE 636
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
976-1191 |
5.24e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 5.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 976 ELQTKLNSELSALEKQKDE---KITQQEEKYKALIQNLEKDKQRLAmnheqDKEQLIQKLNfEKDEAIQTALDEFKLERE 1052
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAElekELAALKKEEKALLKQLAALERRIA-----ALARRIRALE-QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1053 LVEKELLEKVKHLENQIAKspAFESAREDSSSLVAELQEKLQEEK-AKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTnfn 1131
Cdd:COG4942 94 ELRAELEAQKEELAELLRA--LYRLGRQPPLALLLSPEDFLDAVRrLQYLKYLAPARREQAEELRADLAELAALRAE--- 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1132 tvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEekkkleeEVSKLR 1191
Cdd:COG4942 169 --LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA-------ELAELQ 219
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
799-1130 |
5.46e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 44.36 E-value: 5.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 799 EEFEKVITDHKVSL-EKLKKENQQKIDQMLESHAS---AIQEKEQQLQELKVKVSDLSDmrcklEVELALKEAETDEIKI 874
Cdd:pfam09731 84 EEKKQVKIPRQSGVsSEVAEEEKEATKDAAEAKAQlpkSEQEKEKALEEVLKEAISKAE-----SATAVAKEAKDDAIQA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 875 LLEE-------------SRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISR 941
Cdd:pfam09731 159 VKAHtdslkeasdtaeiSREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKA 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 942 HEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELqtklnSELSALEKqkdekitqqeEKYKALIQNLEKDKQRLamnh 1021
Cdd:pfam09731 239 QSLAKLVDQYKELVASERIVFQQELVSIFPDIIPVL-----KEDNLLSN----------DDLNSLIAHAHREIDQL---- 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1022 eqdkEQLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVK-HLENQIAKSPA-FESAREDS-----SSLVAELQEKLQ 1094
Cdd:pfam09731 300 ----SKKLAELKKREEKHIERALEKQKEELDKLAEELSARLEeVRAADEAQLRLeFEREREEIresyeEKLRTELERQAE 375
|
330 340 350
....*....|....*....|....*....|....*.
gi 1958775931 1095 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNF 1130
Cdd:pfam09731 376 AHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGR 411
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
647-1144 |
5.85e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 5.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 647 NIIDK-VKCSLEITLKEKhQQELQslKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEAL------QNKDSEFAIIKH 719
Cdd:TIGR01612 958 NLIEKsYKDKFDNTLIDK-INELD--KAFKDASLNDYEAKNNELIKYFNDLKANLGKNKENMlyhqfdEKEKATNDIEQK 1034
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 720 EKDAivcmqhekDQKLLEMENIMHTqnseikelkqSREMVLEDLKKLHDEKIESL------RAEFQCLEQNHLKE----- 788
Cdd:TIGR01612 1035 IEDA--------NKNIPNIEIAIHT----------SIYNIIDEIEKEIGKNIELLnkeileEAEINITNFNEIKEklkhy 1096
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 789 -LEDTL---HIRHTEEFEKVitdhkvsleklkKENQQKIDQMLESHASAIQE----KEQQLQELKVKVSDLSDMrckleV 860
Cdd:TIGR01612 1097 nFDDFGkeeNIKYADEINKI------------KDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDV-----A 1159
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 861 ELALKEAETDEIKILLEESRTqqKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQcISELIS 940
Cdd:TIGR01612 1160 DKAISNDDPEEIEKKIENIVT--KIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEK-IDEEKK 1236
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 941 RHEEESNILKAELDSVTALHHQAFEIEKKLKeqiveLQTKLNSELSAL-------------EKQKDEKITQQEEKYKALI 1007
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDLDEIKEKSPEIENEMG-----IEMDIKAEMETFnishdddkdhhiiSKKHDENISDIREKSLKII 1311
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1008 QNLEKDKQRLAMNHEQDKEQL-IQKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAK-SPAFESAREDSSSL 1085
Cdd:TIGR01612 1312 EDFSEESDINDIKKELQKNLLdAQKHNSDINLYLNEIANIYNILKLNKIKKIIDEVKEYTKEIEEnNKNIKDELDKSEKL 1391
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958775931 1086 VAELQE--KLQEEKAKFLEQLEeqEKRKNEEMQNVRTS--LIAEQQTNFNTVLTREKMRKENI 1144
Cdd:TIGR01612 1392 IKKIKDdiNLEECKSKIESTLD--DKDIDECIKKIKELknHILSEESNIDTYFKNADENNENV 1452
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
988-1153 |
5.88e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 988 LEKQKDEKITQQEEKYKALIQNLEKDKQRLamnheqdkeqliqklnfeKDEAIQTALDEFKLERELVEKELLEK---VKH 1064
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAI------------------KKEALLEAKEEIHKLRNEFEKELRERrneLQK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1065 LENQIAKSpafESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNvrtsLIAEQQTNFNTV--LTREKMRKE 1142
Cdd:PRK12704 87 LEKRLLQK---EENLDRKLELLEKREEELEKKEKE-LEQKQQELEKKEEELEE----LIEEQLQELERIsgLTAEEAKEI 158
|
170
....*....|.
gi 1958775931 1143 nIINDLSDKLK 1153
Cdd:PRK12704 159 -LLEKVEEEAR 168
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
575-1172 |
7.55e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 7.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 575 SRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDLCHFRTFVQKEQCDLSNYLKCTAVEIRNIIDKVKC 654
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 655 SLEitLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQK 734
Cdd:TIGR02169 309 SIA--EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 735 LLEMENIMHTQNSEIKELKQSREMVLEDLKKLHdEKIESLRAEFQCLEQNHlKELEDTLhirhteefekvitdhKVSLEK 814
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLS-EELADLNAAIAGIEAKI-NELEEEK---------------EDKALE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 815 LKKENQQkidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKE--------- 885
Cdd:TIGR02169 450 IKKQEWK-----LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvh 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 886 -TLKSLLEQE-----------------------------TENLRTE---------INKLNQKIHDNSESYQVG------- 919
Cdd:TIGR02169 525 gTVAQLGSVGeryataievaagnrlnnvvveddavakeaIELLKRRkagratflpLNKMRDERRDLSILSEDGvigfavd 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 920 ------------------------LSELRSLM------TIEKD-----------------------------QCISELIS 940
Cdd:TIGR02169 605 lvefdpkyepafkyvfgdtlvvedIEAARRLMgkyrmvTLEGElfeksgamtggsraprggilfsrsepaelQRLRERLE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 941 RHEEESNILKAELDSVTALHHQAF-----------EIEK----------KLKEQIVELQTKLNSELSALEKQKDE----- 994
Cdd:TIGR02169 685 GLKRELSSLQSELRRIENRLDELSqelsdasrkigEIEKeieqleqeeeKLKERLEELEEDLSSLEQEIENVKSElkele 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 995 -KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFE--KDEAIQTALDEfKLERELVEKELLEK-VKHLENQI- 1069
Cdd:TIGR02169 765 aRIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsRIEARLREIEQ-KLNRLTLEKEYLEKeIQELQEQRi 843
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1070 ---AKSPAFESAREDSSSLVAELQEKLqEEKAKFLEQLEEQEKRKNEEMQNVRTSLiAEQQTNFNTvLTREKMRKENIIN 1146
Cdd:TIGR02169 844 dlkEQIKSIEKEIENLNGKKEELEEEL-EELEAALRDLESRLGDLKKERDELEAQL-RELERKIEE-LEAQIEKKRKRLS 920
|
730 740
....*....|....*....|....*.
gi 1958775931 1147 DLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR02169 921 ELKAKLEALEEELSEIEDPKGEDEEI 946
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
114-339 |
7.62e-04 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 43.53 E-value: 7.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 114 NVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAikgLEDRLYALDQMIASCSRLVNEQKELAQG 193
Cdd:pfam04108 127 ELQAAQESLDSDLKRFDDDLRDLQKELESLSSPSESISLIPTLLKELES---LEEEMASLLESLTNHYDQCVTAVKLTEG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 194 FLANqMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHV------RLKWCCFVMLHADQDG 267
Cdd:pfam04108 204 GRAE-MLEVLENDARELDDVVPELQDRLDEMENNYERLQKLLEQKNSLIDELLSALQLiaeiqsRLPEYLAALKEFEERW 282
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 268 EKLQALLRLVIELLERVRivEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESF 339
Cdd:pfam04108 283 EEEKETIEDYLSELEDLR--EFYEGFPSAYGSLLLEVERRREWAEKMKKILRKLAEELDRLQEEERKRREKF 352
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
676-1158 |
7.83e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 44.27 E-value: 7.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 676 ECKLNTLEKDSEenvNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELK-- 753
Cdd:TIGR00606 690 EAELQEFISDLQ---SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKnd 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 754 -QSREMVLEDLKKlHDEKIESLRAEFQCLEQNHLkELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQK------IDQM 826
Cdd:TIGR00606 767 iEEQETLLGTIMP-EEESAKVCLTDVTIMERFQM-ELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqheldtVVSK 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 827 LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAetdeikilleesrtqqketlkslLEQETENLRTEINKLN 906
Cdd:TIGR00606 845 IELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ-----------------------FEEQLVELSTEVQSLI 901
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 907 QKIHDNSEsyqvglSELRSLMTIEKDQC-ISELISRHEEESNILKAELDsvtalhhqafEIEKKLKEQIVELQTKLNSel 985
Cdd:TIGR00606 902 REIKDAKE------QDSPLETFLEKDQQeKEELISSKETSNKKAQDKVN----------DIKEKVKNIHGYMKDIENK-- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 986 saLEKQKDEKITQQEEKYKALIQNLEKDKQRlAMNHEQDKEQLIQKLNFEK--DEAIQTALDEFKLERELveKELLEKVK 1063
Cdd:TIGR00606 964 --IQDGKDDYLKQKETELNTVNAQLEECEKH-QEKINEDMRLMRQDIDTQKiqERWLQDNLTLRKRENEL--KEVEEELK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1064 HLENQIAKSPAFESAREDSsslvaELQEKLQ---EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMR 1140
Cdd:TIGR00606 1039 QHLKEMGQMQVLQMKQEHQ-----KLEENIDlikRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTT 1113
|
490
....*....|....*...
gi 1958775931 1141 KEnIINDLsDKLKSTMQQ 1158
Cdd:TIGR00606 1114 EL-VNKDL-DIYYKTLDQ 1129
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
738-886 |
7.89e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.08 E-value: 7.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 738 MENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEsLRAEFQCL--EQNHLKELEDTLHIRHTEEFEKVitdhKVSLEKL 815
Cdd:smart00787 142 LEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPK-LRDRKDALeeELRQLKQLEDELEDCDPTELDRA----KEKLKKL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 816 KKENQQKIDQmleshasaIQEKEQQLQELKVKVSDLSDMrcKLEVELALKEAET----------DEIKILLEESRTQQKE 885
Cdd:smart00787 217 LQEIMIKVKK--------LEELEEELQELESKIEDLTNK--KSELNTEIAEAEKkleqcrgftfKEIEKLKEQLKLLQSL 286
|
.
gi 1958775931 886 T 886
Cdd:smart00787 287 T 287
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
790-1113 |
7.94e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 43.98 E-value: 7.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 790 EDTLHIRHTEEFEKVITDHKVSLEKLKKENQQKI----DQMLESHASAIQEKEQQLQELKVKVSDLSDMRCK-LEVELAL 864
Cdd:pfam09731 108 ATKDAAEAKAQLPKSEQEKEKALEEVLKEAISKAesatAVAKEAKDDAIQAVKAHTDSLKEASDTAEISREKaTDSALQK 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 865 KEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHD--NSESYQVGLSELRSLMTIEKDQCISELISRH 942
Cdd:pfam09731 188 AEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKveKAQSLAKLVDQYKELVASERIVFQQELVSIF 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 943 -------EEESNILKAELDSVTAlhhqafeiekKLKEQIvelqTKLNSELSALEKQKDEKITQQEEKykaliQNLEKDKQ 1015
Cdd:pfam09731 268 pdiipvlKEDNLLSNDDLNSLIA----------HAHREI----DQLSKKLAELKKREEKHIERALEK-----QKEELDKL 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1016 RlamnheqdkEQLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVK------------HLENQIAkspafESAREDSS 1083
Cdd:pfam09731 329 A---------EELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRtelerqaeaheeHLKDVLV-----EQEIELQR 394
|
330 340 350
....*....|....*....|....*....|
gi 1958775931 1084 SLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:pfam09731 395 EFLQDIKEKVEEERAGRLLKLNELLANLKG 424
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
821-977 |
1.03e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 821 QKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKS----LLEQETE 896
Cdd:COG1579 20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkeyeALQKEIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 897 NLRTEINKLNQKI---HDNSESYQVGLSELRSLMTIEKDQcISELISRHEEESNILKAELDSVTAlhhQAFEIEKKLKEQ 973
Cdd:COG1579 100 SLKRRISDLEDEIlelMERIEELEEELAELEAELAELEAE-LEEKKAELDEELAELEAELEELEA---EREELAAKIPPE 175
|
....
gi 1958775931 974 IVEL 977
Cdd:COG1579 176 LLAL 179
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
785-1146 |
1.22e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.50 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 785 HLKELEDTLHIRHTEEFEKVITDHKVSLE---KLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVE 861
Cdd:TIGR01612 501 RMKDFKDIIDFMELYKPDEVPSKNIIGFDidqNIKAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKE 580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 862 ---LALKEAETDEIKILLEESRTQQKETLKSLLEQeTENLRTEINKlnQKIHDNSESYQVGLSELRSLMTIE----KDQC 934
Cdd:TIGR01612 581 ikdLFDKYLEIDDEIIYINKLKLELKEKIKNISDK-NEYIKKAIDL--KKIIENNNAYIDELAKISPYQVPEhlknKDKI 657
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 935 ISELISrheEESNILKAELDsvtALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDK 1014
Cdd:TIGR01612 658 YSTIKS---ELSKIYEDDID---ALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKK 731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1015 QRLAMNHEQDKEQLIQKLNFEkdeaIQTALDEFKlerelvekellEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQ 1094
Cdd:TIGR01612 732 NELLDIIVEIKKHIHGEINKD----LNKILEDFK-----------NKEKELSNKINDYAKEKDELNKYKSKISEIKNHYN 796
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1958775931 1095 EEKAkfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIIN 1146
Cdd:TIGR01612 797 DQIN--IDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLN 846
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
750-915 |
1.35e-03 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 42.93 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 750 KELKQSREM-VLEDLKKLHDE-KIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQML 827
Cdd:pfam02029 186 KEKKVKYESkVFLDQKRGHPEvKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEF 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 828 ESHASAIQEKEQQLQELKVKvsdLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslleqETENLRTEINKLNQ 907
Cdd:pfam02029 266 EKLRQKQQEAELELEELKKK---REERRKLLEEEEQRRKQEEAERKLREEEEKRRMKE--------EIERRRAEAAEKRQ 334
|
....*...
gi 1958775931 908 KIHDNSES 915
Cdd:pfam02029 335 KLPEDSSS 342
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
759-994 |
2.27e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 2.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 759 VLEDLKKLHDEKIESLRAEFQCLEqnhlkeledtLHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKE 838
Cdd:PHA02562 164 VLSEMDKLNKDKIRELNQQIQTLD----------MKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 839 QQLQELKVKVS-------DLSDMRCKLEVELALKEAETDEIK------------------ILLEESRTQQKETLKSLLEQ 893
Cdd:PHA02562 234 AEIEELTDELLnlvmdieDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcptctqqISEGPDRITKIKDKLKELQH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 894 ETENLRTEINKLNQKIHDNSESyQVGLSELRSLMTIEKDQciselISRHEEESNILKAELDSVTAlhhqAFEIEKKLKEQ 973
Cdd:PHA02562 314 SLEKLDTAIDELEEIMDEFNEQ-SKKLLELKNKISTNKQS-----LITLVDKAKKVKAAIEELQA----EFVDNAEELAK 383
|
250 260
....*....|....*....|.
gi 1958775931 974 IVELQTKLNSELSALEKQKDE 994
Cdd:PHA02562 384 LQDELDKIVKTKSELVKEKYH 404
|
|
| OmpH |
smart00935 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
980-1071 |
2.40e-03 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 39.87 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 980 KLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELL 1059
Cdd:smart00935 18 AAQKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQEELQKIL 97
|
90
....*....|..
gi 1958775931 1060 EKVKHLENQIAK 1071
Cdd:smart00935 98 DKINKAIKEVAK 109
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
930-1161 |
2.47e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 930 EKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQtKLNSELSALEKQkdekITQQEEKYKALIQN 1009
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAE----LAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1010 LEKDKQRLA-------MNHEQDKEQLIqkLNFEkdeaiqtalDEFKLERELvekELLEKV-KHLENQIAkspAFESARED 1081
Cdd:COG4942 99 LEAQKEELAellralyRLGRQPPLALL--LSPE---------DFLDAVRRL---QYLKYLaPARREQAE---ELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1082 SSSLVAELQEKlQEEKAKFLEQLEEQEKRKNEEMQNvRTSLIAEQQTNFNTVLTR--EKMRKENIINDLSDKLKSTMQQQ 1159
Cdd:COG4942 162 LAALRAELEAE-RAELEALLAELEEERAALEALKAE-RQKLLARLEKELAELAAElaELQQEAEELEALIARLEAEAAAA 239
|
..
gi 1958775931 1160 ER 1161
Cdd:COG4942 240 AE 241
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
753-908 |
3.18e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 753 KQSREMVLEDLKKLhDEKIESLraefqcleQNHLKELEDtlHIRHTEEFEKvitdhkvSLEKLKKENQQKIDQMLESHAS 832
Cdd:PRK00409 505 EEAKKLIGEDKEKL-NELIASL--------EELERELEQ--KAEEAEALLK-------EAEKLKEELEEKKEKLQEEEDK 566
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775931 833 AIQEKEQQLQElkvkvsdlsdmrcklevelALKEAeTDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQK 908
Cdd:PRK00409 567 LLEEAEKEAQQ-------------------AIKEA-KKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEK 622
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
817-1113 |
3.76e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 3.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 817 KENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQE 894
Cdd:COG4372 9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELeeLNEQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 895 TENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciselisrhEEESNILKAELDSVTALHHQAFEIEKKLKEQI 974
Cdd:COG4372 89 LQAAQAELAQAQEELESLQEEAEELQEELEEL----------------QKERQDLEQQRKQLEAQIAELQSEIAEREEEL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 975 VELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELV 1054
Cdd:COG4372 153 KELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLG 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958775931 1055 EKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:COG4372 233 LALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEA 291
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
656-1109 |
3.85e-03 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 41.96 E-value: 3.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 656 LEITLKEKHQQELQ--------SLKIEYECKLNTLEKDSEENVNKILKLKEDL------VSLEEALQNKDS-EFAIIKH- 719
Cdd:PTZ00108 906 LESETLKEKDVIVDyrdystanTVHFTVKLNDGVLEQWEEEGIEKVFKLKSTIsttnmvLFDENGKIKKYSdALDILKEf 985
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 720 ----------EKDAIVcMQHEKDQKLLE--MENIMHTQNSEIKELKQSREMVLEDLKKL--------HDEKIESLRA--E 777
Cdd:PTZ00108 986 ylvrldlykkRKEYLL-GKLERELARLSnkVRFIKHVINGELVITNAKKKDLVKELKKLgyvrfkdiIKKKSEKITAeeE 1064
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 778 FQCLEQNHLKELEDTLHIRHTEEFEKVItdhKVSLEKLKKEnqqKIDQMLESHAsaiqEKEQQLQELKVKVSDLSDMRCK 857
Cdd:PTZ00108 1065 EGAEEDDEADDEDDEEELGAAVSYDYLL---SMPIWSLTKE---KVEKLNAELE----KKEKELEKLKNTTPKDMWLEDL 1134
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 858 LEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETEnLRTEINKLNQKIHDNSesyqvglselRSLMTIEKDQCISE 937
Cdd:PTZ00108 1135 DKFEEALEEQEEVEEKEIAKEQRLKSKTKGKASKLRKPK-LKKKEKKKKKSSADKS----------KKASVVGNSKRVDS 1203
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 938 LISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLN--SELSALEKQKDEKITQQEEKYKALIQNLEKDKQ 1015
Cdd:PTZ00108 1204 DEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNnsSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQY 1283
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1016 RLAMNHEQDKEqliqklnfEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQE 1095
Cdd:PTZ00108 1284 SPPPPSKRPDG--------ESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRR 1355
|
490
....*....|....
gi 1958775931 1096 EKAKFLEQLEEQEK 1109
Cdd:PTZ00108 1356 PRKKKSDSSSEDDD 1369
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
924-1063 |
5.29e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.35 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 924 RSLMTIEKDQcISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKY 1003
Cdd:PRK00409 508 KKLIGEDKEK-LNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEA 586
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1004 KALIQNLekdKQRLAMNHEQDKEQLIQklnfEKDEAIQTALDEFKlERELVEKELLEKVK 1063
Cdd:PRK00409 587 DEIIKEL---RQLQKGGYASVKAHELI----EARKRLNKANEKKE-KKKKKQKEKQEELK 638
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
873-1120 |
6.98e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.68 E-value: 6.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 873 KILLEESRTQQKETLKSLLEQ---ETENLRTEINklNQKIHDNSESYQV---GLSELRSLMTIE----------KDQCIS 936
Cdd:PRK05771 8 KVLIVTLKSYKDEVLEALHELgvvHIEDLKEELS--NERLRKLRSLLTKlseALDKLRSYLPKLnplreekkkvSVKSLE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 937 ELISRHEEESNILkaeLDSVTALHHQAFEIE---KKLKEQIVELQ--TKLNSELSAL-------------EKQKDEKITQ 998
Cdd:PRK05771 86 ELIKDVEEELEKI---EKEIKELEEEISELEneiKELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgtvPEDKLEELKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 999 QEEKYKALIQNLEKDKQRLAM----NHEQDKEQLIQKLNFEKDE-----AIQTALDEFKLERELVEKELlekvKHLENQI 1069
Cdd:PRK05771 163 ESDVENVEYISTDKGYVYVVVvvlkELSDEVEEELKKLGFERLEleeegTPSELIREIKEELEEIEKER----ESLLEEL 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1958775931 1070 akspafesaredssslvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRT 1120
Cdd:PRK05771 239 -----------------KELAKKYLEELLALYEYLEIELERAEALSKFLKT 272
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
577-1171 |
7.49e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 7.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 577 RMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHI--------SIQTIKDDLCHFRTFVQKEQCDLSNyLKCTAVEIRNI 648
Cdd:TIGR01612 1611 KISDIKKKINDCLKETESIEKKISSFSIDSQDTELkengdnlnSLQEFLESLKDQKKNIEDKKKELDE-LDSEIEKIEID 1689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 649 IDKVKCSLEITLKEKHQQELQSLKIEYEcKLNTLEKDSEENVNKILKLKE-DLVSLEEALQNKDSEFAIIKHEKDAIVCM 727
Cdd:TIGR01612 1690 VDQHKKNYEIGIIEKIKEIAIANKEEIE-SIKELIEPTIENLISSFNTNDlEGIDPNEKLEEYNTEIGDIYEEFIELYNI 1768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 728 QhEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKV--- 804
Cdd:TIGR01612 1769 I-AGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSYLDDIEAKEFDRIINHFKKKLDHVNDKFTKEYSKIneg 1847
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 805 ITDHKVSLEKLKKENQQK-----IDQMLESHASAIQEKEQQLQELKVKV-SDLSDMRCKLEVELALKEAET--DEIKI-L 875
Cdd:TIGR01612 1848 FDDISKSIENVKNSTDENllfdiLNKTKDAYAGIIGKKYYSYKDEAEKIfINISKLANSINIQIQNNSGIDlfDNINIaI 1927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 876 LEESRTQQKETLKSLLEQETE-NLRTEI-NKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNIL---- 949
Cdd:TIGR01612 1928 LSSLDSEKEDTLKFIPSPEKEpEIYTKIrDSYDTLLDIFKKSQDLHKKEQDTLNIIFENQQLYEKIQASNELKDTLsdlk 2007
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 950 -KAE--LDSVTALHHQAFEIEK-----KLKEQIVEL--QTKLNSELSALEKQK-----DEKITQQEEKYKALIQNLEKDK 1014
Cdd:TIGR01612 2008 yKKEkiLNDVKLLLHKFDELNKlscdsQNYDTILELskQDKIKEKIDNYEKEKekfgiDFDVKAMEEKFDNDIKDIEKFE 2087
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1015 qrlamNHEQDKEQLIQKLNFEKDEAIQT--ALDE----FKLERELVEKELLEKvKHLENQIAKSPAfESAREDSSSLVAE 1088
Cdd:TIGR01612 2088 -----NNYKHSEKDNHDFSEEKDNIIQSkkKLKElteaFNTEIKIIEDKIIEK-NDLIDKLIEMRK-ECLLFSYATLVET 2160
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1089 LQEKLQEEkAKFLEQLEEQEKRKNEEMQNVRTSL---IAEQQTNFNTVLTREKMrkENIINDLSDKLKSTMQQQERDKDL 1165
Cdd:TIGR01612 2161 LKSKVINH-SEFITSAAKFSKDFFEFIEDISDSLnddIDALQIKYNLNQTKKHM--ISILADATKDHNNLIEKEKEATKI 2237
|
....*.
gi 1958775931 1166 IESLSE 1171
Cdd:TIGR01612 2238 INNLTE 2243
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
656-973 |
7.55e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 40.66 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 656 LEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiikhekdaivcmQHEKDQKL 735
Cdd:PLN02939 65 LQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDG--------------EQLSDFQL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 736 LEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQN----------------HLKELEDTLHIRHTE 799
Cdd:PLN02939 131 EDLVGMIQNAEKNILLLNQARLQALEDLEKILTEK-EALQGKINILEMRlsetdariklaaqekiHVEILEEQLEKLRNE 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 800 EFEKVITDHKV------SLEKLKKENQQKID--QMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDE 871
Cdd:PLN02939 210 LLIRGATEGLCvhslskELDVLKEENMLLKDdiQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSK 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 872 IKILLEESRTQQKETLKSLLEQETENLRTEINKL--NQKIHDNSESYQVGLSELR-SLMTIEKDQCISELISRHEEESNI 948
Cdd:PLN02939 290 LSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLdqNQDLRDKVDKLEASLKEANvSKFSSYKVELLQQKLKLLEERLQA 369
|
330 340
....*....|....*....|....*....
gi 1958775931 949 LKAELDSVTALHHQAF----EIEKKLKEQ 973
Cdd:PLN02939 370 SDHEIHSYIQLYQESIkefqDTLSKLKEE 398
|
|
| FAM184 |
pfam15665 |
Family with sequence similarity 184, A and B; The function of FAM184 is not known. |
659-848 |
8.10e-03 |
|
Family with sequence similarity 184, A and B; The function of FAM184 is not known.
Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 39.26 E-value: 8.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 659 TLKEKHQQELQSLKIEYECKLNTLEKDSEENvnkiLKLKEDLVSLEEALQnkdsefaiikhekdaivcmQHEKDQKLLEM 738
Cdd:pfam15665 18 ALKEAHEEEIQQILAETREKILQYKSKIGEE----LDLKRRIQTLEESLE-------------------QHERMKRQALT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 739 ENIMHTQNSEIKELKQ-----------SREMvlEDLKKLHDEKIESLRAEFQCLEQNHLKELEDtLHIRHTEEFEKVITD 807
Cdd:pfam15665 75 EFEQYKRRVEERELKAeaehrqrvvelSREV--EEAKRAFEEKLESFEQLQAQFEQEKRKALEE-LRAKHRQEIQELLTT 151
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1958775931 808 HKVSLEKLKKEnQQKIDQMLESHASAIQEKEQQLQELKVKV 848
Cdd:pfam15665 152 QRAQSASSLAE-QEKLEELHKAELESLRKEVEDLRKEKKKL 191
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
661-842 |
8.55e-03 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 40.51 E-value: 8.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 661 KEKHQQELQSLKIEYECKLNTLEKDSEENVNK-ILKLKEDLVSLEEALQN-KDSEFaiiKHEKDAIvcMQHEKDQKLLEM 738
Cdd:pfam09731 256 RIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSlIAHAHREIDQLSKKLAElKKREE---KHIERAL--EKQKEELDKLAE 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 739 ENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTE---EFEKVITDhKVSLEK- 814
Cdd:pfam09731 331 ELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQEIElqrEFLQDIKE-KVEEERa 409
|
170 180 190
....*....|....*....|....*....|....*..
gi 1958775931 815 --LKKENQQK-----IDQMLESHASAIQE--KEQQLQ 842
Cdd:pfam09731 410 grLLKLNELLanlkgLEKATSSHSEVEDEnrKAQQLW 446
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
877-1169 |
9.84e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.39 E-value: 9.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 877 EESRTQQKETLKS--LLEQETENLrteinKLNQKIHDNSESYQVGLSELRSLMTIEkdqciselisrHEEESNILKAELD 954
Cdd:COG3206 80 DSPLETQIEILKSrpVLERVVDKL-----NLDEDPLGEEASREAAIERLRKNLTVE-----------PVKGSNVIEISYT 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 955 SVTAlhHQAFEIEKKLKEQIVELQTKLNSELSaleKQKDEKITQQEEKYKALIQNLEKDKQRLAMNH-----EQDKEQLI 1029
Cdd:COG3206 144 SPDP--ELAAAVANALAEAYLEQNLELRREEA---RKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLL 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775931 1030 QKLNfekdeAIQTALDEFKLERELVE------KELLEKVKHLENQIAKSPAFESAREDSSSLVAELQE------------ 1091
Cdd:COG3206 219 QQLS-----ELESQLAEARAELAEAEarlaalRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAElsarytpnhpdv 293
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958775931 1092 -KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTnfntvLTREKMRKENIINDLSDKLkSTMQQQERDKDLIESL 1169
Cdd:COG3206 294 iALRAQIAALRAQLQQEAQRILASLEAELEALQAREAS-----LQAQLAQLEARLAELPELE-AELRRLEREVEVAREL 366
|
|
| |
