|
Name |
Accession |
Description |
Interval |
E-value |
| Cnn_1N |
pfam07989 |
Centrosomin N-terminal motif 1; This domain has been identified in two microtubule associated ... |
61-129 |
1.88e-19 |
|
Centrosomin N-terminal motif 1; This domain has been identified in two microtubule associated proteins in Schizosaccharomyces pombe, Mto1 and Pcp1. Mto1 has been identified in association with spindle pole body and non-spindle pole body microtubules. The pericentrin homolog Pcp1 is also associated with the fungal centrosome or spindle pole body (SPB). Members of this family have been named centrosomins, and are an essential mitotic centrosome component required for assembly of all other known pericentriolar matrix proteins in order to achieve microtubule-organizing activity in fission yeast. Cnn_1N is a short conserved motif towards the N-terminus. Motif 1 is found to be necessary for proper recruitment of gamma-tubulin, D-TACC (the homolog of vertebrate transforming acidic coiled-coil proteins [TACC]), and Minispindles (Msps) to embryonic centrosomes but is not required for assembly of other centrosome components including Aurora A kinase and CP60 in Drosophila.
Pssm-ID: 462333 [Multi-domain] Cd Length: 69 Bit Score: 83.72 E-value: 1.88e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958774896 61 KDFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASK 129
Cdd:pfam07989 1 REQEKQIDKLKKENFNLKLKIHFLEERLEKLAPEQIEEALKENIELKVELETLQRELKKLKKLLREAEK 69
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
146-471 |
2.48e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 2.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 146 KEDARKKVQQVEELLTkRIHLLEEDVKAAQAELEKafagtETEKALR----------LSLESKLSAMKKMQEGDLEMTLA 215
Cdd:COG1196 174 KEEAERKLEATEENLE-RLEDILGELERQLEPLER-----QAEKAERyrelkeelkeLEAELLLLKLRELEAELEELEAE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 216 LEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASpDENVSSGELRGLSATLrEEKERDAEERQKERNHFEERIQALQEDL 295
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELEL-ELEEAQAEEYELLAEL-ARLEQDIARLEERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 296 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENcEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELND 375
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEA-EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 376 LKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLpgessskfHSQEQVVKGLTESASQED 455
Cdd:COG1196 405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE--------EALLELLAELLEEAALLE 476
|
330
....*....|....*.
gi 1958774896 456 LLLQKSNEKDLEAIQQ 471
Cdd:COG1196 477 AALAELLEELAEAAAR 492
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
49-427 |
8.93e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.93 E-value: 8.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 49 EEKVSPTRAR--NMKDFENQITELKKENFNLKLRIYFLEERIQQ------EFAGPTEHIYKKNIELK---------VEVE 111
Cdd:PRK03918 220 REELEKLEKEvkELEELKEEIEELEKELESLEGSKRKLEEKIREleerieELKKEIEELEEKVKELKelkekaeeyIKLS 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 112 SLKRELQERDQLLVKASKAVESLAEGggseIQRVKEDARKKVQQVEELLTKRI------------HLLEEDVKAAQAELE 179
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEING----IEERIKELEEKEERLEELKKKLKelekrleeleerHELYEEAKAKKEELE 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 180 ---KAFAGTETEKalrlsLESKLSAMKKMQEgdlEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSS 256
Cdd:PRK03918 376 rlkKRLTGLTPEK-----LEKELEELEKAKE---EIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 257 GELRGLSATLREEKERDAEERQKernhFEERIQALQEDLREKEREIATEKKNSLKRDKA--IQGLTMALKSKEKEESENC 334
Cdd:PRK03918 448 EHRKELLEEYTAELKRIEKELKE----IEEKERKLRKELRELEKVLKKESELIKLKELAeqLKELEEKLKKYNLEELEKK 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 335 EAALAEKEALLAKLHSEnvtkntenhrlLRNVKKVTQELNDLKKEKLRLERDLEEAHREgnrGARTIHDLRNEVEKLRKE 414
Cdd:PRK03918 524 AEEYEKLKEKLIKLKGE-----------IKSLKKELEKLEELKKKLAELEKKLDELEEE---LAELLKELEELGFESVEE 589
|
410
....*....|...
gi 1958774896 415 VCEREKAVEKHYK 427
Cdd:PRK03918 590 LEERLKELEPFYN 602
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
105-621 |
1.64e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 105 ELKVEVESLKRELQERDQLLVKASKAVESLAEgggsEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKAFAG 184
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELEL----ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 185 TETEKALRLSLESKLSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSA 264
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 265 TLREEKER-DAEERQKERNHFEERIQALQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEA 343
Cdd:COG1196 406 EEAEEALLeRLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 344 LLAKLHSENVTKNTENH-----------RLLRNVKKVTQELNDLKKEKLRLERDLEEAH--REGNRGARTIHDLRNEVEK 410
Cdd:COG1196 486 LAEAAARLLLLLEAEADyegflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaALQNIVVEDDEVAAAAIEY 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 411 LRKEVCEREKAV--EKHYKSLPGESSSKFHSQEQVVKGLTESASQEDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGL 488
Cdd:COG1196 566 LKAAKAGRATFLplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 489 ITEKcSQQSPDSKLIFSKEKQQS--EYEGLTGDLKTEQNVYAHLAKNLQDTDSKLQAELKRVLALRKQLEQDVLAYRNLQ 566
Cdd:COG1196 646 LREV-TLEGEGGSAGGSLTGGSRreLLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 1958774896 567 TALQEQLSEIRKREEEPFSFYSDQtsylsicLEEHSQFQLEHFSQEEIKKKVIDL 621
Cdd:COG1196 725 ALEEQLEAEREELLEELLEEEELL-------EEEALEELPEPPDLEELERELERL 772
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
85-637 |
5.29e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.70 E-value: 5.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 85 EERIQQEFAGPTEHIYKknIELKVEVESLKRELQERDQLLVKASKAVESLAEGGGSEIQRVKEDARK--KVQQVEELLTK 162
Cdd:PTZ00121 1113 EARKAEEAKKKAEDARK--AEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKaeAARKAEEVRKA 1190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 163 RIHLLEEDVKAAQaELEKAFAGTETEKALRLSLESKLSAMKKMQEG--DLEMTLALEEKDRLIEELKLSLKSKEALIQCL 240
Cdd:PTZ00121 1191 EELRKAEDARKAE-AARKAEEERKAEEARKAEDAKKAEAVKKAEEAkkDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 241 KEEKSQMASPDENVSSGELRGLSATLR--------EEKERDAEERQK--ERNHFEERIQALQEDLREKEREiaTEKKNSL 310
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEKKKADEAKkaeekkkaDEAKKKAEEAKKadEAKKKAEEAKKKADAAKKKAEE--AKKAAEA 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 311 KRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLE------ 384
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADeakkka 1427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 385 ---RDLEEAHREGNRgARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSSKFHSQEQVVKGLTESASQEDLLLQKS 461
Cdd:PTZ00121 1428 eekKKADEAKKKAEE-AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 462 NEKDleaiqqncylmTAEELKFGSDGLITEKCSQQSPDSKlifSKEKQQSEYEGLTGDLKTEQNVYAhlAKNLQDTDSKL 541
Cdd:PTZ00121 1507 EAKK-----------KADEAKKAEEAKKADEAKKAEEAKK---ADEAKKAEEKKKADELKKAEELKK--AEEKKKAEEAK 1570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 542 QAELKRVLALRKQLEqdvlayrnLQTALQEQLSEIRKREEEPFSFYSDQTSYlsiclEEHSQFQLEHFSQ-EEIKKKVID 620
Cdd:PTZ00121 1571 KAEEDKNMALRKAEE--------AKKAEEARIEEVMKLYEEEKKMKAEEAKK-----AEEAKIKAEELKKaEEEKKKVEQ 1637
|
570
....*....|....*..
gi 1958774896 621 LIQLVKDLHADNQHLKK 637
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKK 1654
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
60-436 |
1.51e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.08 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 60 MKDFENQITELKKENFNLKLRIYFLEERIQQ--EFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEG 137
Cdd:PRK03918 302 YEEYLDELREIEKRLSRLEEEINGIEERIKEleEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 138 GGSEIQRVK------EDARKKVQQVEELLTKRIHLLE---EDVKAAQAELEKAFAGTETEKALrLSLESKLSAMKKMQeg 208
Cdd:PRK03918 382 TGLTPEKLEkeleelEKAKEEIEEEISKITARIGELKkeiKELKKAIEELKKAKGKCPVCGRE-LTEEHRKELLEEYT-- 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 209 dLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKS-----QMASPDENVSSgELRGLSATLREEKERDAEERQKERNH 283
Cdd:PRK03918 459 -AELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliklkELAEQLKELEE-KLKKYNLEELEKKAEEYEKLKEKLIK 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 284 FEERIQALQEDLR-----EKEREIATEKKNSLKRDKAiqgltmALKSKEKEESENCEAALAEKEALLAKLHSENVTknte 358
Cdd:PRK03918 537 LKGEIKSLKKELEkleelKKKLAELEKKLDELEEELA------ELLKELEELGFESVEELEERLKELEPFYNEYLE---- 606
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958774896 359 nhrllrnVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCERE-KAVEKHYKSLPGESSSK 436
Cdd:PRK03918 607 -------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyEELREEYLELSRELAGL 678
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
142-472 |
4.53e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.53 E-value: 4.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 142 IQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKafagtetekalrlsLESKLSAMKKMQEgdlEMTLALEEKDR 221
Cdd:TIGR02168 205 LERQAEKAERYKELKAELRELELALLVLRLEELREELEE--------------LQEELKEAEEELE---ELTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 222 LIEELKLSLKSKEALIQCLKeeksqmaspdenvssGELRGLSATLrEEKERDAEERQKERNHFEERIQALQEDLREKERE 301
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQ---------------KELYALANEI-SRLEQQKQILRERLANLERQLEELEAQLEELESK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 302 IATEKKNSLKRDKAIQGLtmalkskeKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKL 381
Cdd:TIGR02168 332 LDELAEELAELEEKLEEL--------KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 382 RLERDLEEAHREGNRGARTIHDL-----RNEVEKLRKEVCEREKAVEKHYKSLPGESSSKFHSQEQVVKGLTESASQEDL 456
Cdd:TIGR02168 404 RLEARLERLEDRRERLQQEIEELlkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483
|
330
....*....|....*..
gi 1958774896 457 LLQKSNEKD-LEAIQQN 472
Cdd:TIGR02168 484 LAQLQARLDsLERLQEN 500
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
160-425 |
5.32e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 5.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 160 LTKRIHLLEEDVKAAQAELEKafagtetekalrlsLESKLSAMKKMQEgdlEMTLALEEKDRLIEELKLSLKSKEALIQC 239
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAE--------------LRKELEELEEELE---QLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 240 LKEEKSQMASPDENV-----SSGELRGLSATLREEKERDAEERQKERNHFEERIQALQEDLREKEREIATEKKNSLKRDK 314
Cdd:TIGR02168 745 LEERIAQLSKELTELeaeieELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 315 AIQGLTMALKSKEKEeSENCEAALAEKEALLAKLhsenvTKNTENHRLLRNvkKVTQELNDLKKEKLRLERDLEEAHREG 394
Cdd:TIGR02168 825 RLESLERRIAATERR-LEDLEEQIEELSEDIESL-----AAEIEELEELIE--ELESELEALLNERASLEEALALLRSEL 896
|
250 260 270
....*....|....*....|....*....|.
gi 1958774896 395 NRGARTIHDLRNEVEKLRKEVCEREKAVEKH 425
Cdd:TIGR02168 897 EELSEELRELESKRSELRRELEELREKLAQL 927
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
104-415 |
8.11e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 8.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 104 IELKVEVESLKRELQERDQLLVKASKAVESLAEgggsEIQRVKEDARKKVQQVEELlTKRIHLLEEDVKAAQAELEKAfa 183
Cdd:TIGR02168 673 LERRREIEELEEKIEELEEKIAELEKALAELRK----ELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQL-- 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 184 gteTEKALRLSLESKlsamkkmqEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDEnvssgELRGLS 263
Cdd:TIGR02168 746 ---EERIAQLSKELT--------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE-----ALDELR 809
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 264 ATLREEKERDAEERqkernhfeERIQALQEDLREKEREIATEKKNSLKRDKAIQGLTmalkskekEESENCEAALAEKEA 343
Cdd:TIGR02168 810 AELTLLNEEAANLR--------ERLESLERRIAATERRLEDLEEQIEELSEDIESLA--------AEIEELEELIEELES 873
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958774896 344 LLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREgnrgartIHDLRNEVEKLRKEV 415
Cdd:TIGR02168 874 ELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK-------LAQLELRLEGLEVRI 938
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
84-415 |
1.82e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 56.61 E-value: 1.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 84 LEERIQQEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEGGG--SEIQRVKEDARKKVQQVEellt 161
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEdlSSLEQEIENVKSELKELE---- 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 162 KRIHLLEEDVKAAQAELEKAFAGTETEKalrlsLESKLSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLK 241
Cdd:TIGR02169 765 ARIEELEEDLHKLEEALNDLEARLSHSR-----IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ 839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 242 EE----KSQMASPDENVSSGELRgLSATLREEKERDAEERQ--KERNHFEERIQALQEDLREKEREIATEKKNSLKRDKA 315
Cdd:TIGR02169 840 EQridlKEQIKSIEKEIENLNGK-KEELEEELEELEAALRDleSRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 316 IQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTE------------NHRLLRNVKKVTQELNDLKKEKLRL 383
Cdd:TIGR02169 919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQrveeeiralepvNMLAIQEYEEVLKRLDELKEKRAKL 998
|
330 340 350
....*....|....*....|....*....|..
gi 1958774896 384 ERDLEEahregnrgartIHDLRNEVEKLRKEV 415
Cdd:TIGR02169 999 EEERKA-----------ILERIEEYEKKKREV 1019
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
59-579 |
2.51e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 2.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 59 NMKDFENQITELKKENFNLKLRIYFLEERIQQ---EFAGPTEHIYKKNIE---LKVEVESLKREL----QERDQLLVKAS 128
Cdd:TIGR02168 352 ELESLEAELEELEAELEELESRLEELEEQLETlrsKVAQLELQIASLNNEierLEARLERLEDRRerlqQEIEELLKKLE 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 129 KAVESLAEGGGSEIQRVKEDARKK---VQQVEELLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMK-- 203
Cdd:TIGR02168 432 EAELKELQAELEELEEELEELQEElerLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKal 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 204 KMQEGDLEMTLAL-------EEKDRLIEELKL----------SLKSKEALIQCLKEEKSQMAS--PDENVSSGELRGLSA 264
Cdd:TIGR02168 512 LKNQSGLSGILGVlselisvDEGYEAAIEAALggrlqavvveNLNAAKKAIAFLKQNELGRVTflPLDSIKGTEIQGNDR 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 265 TLREEKE---RDAEERQKERNHFE-------------ERIQALQEDLREKERE--IATEKKNSLKRDKAIQG---LTMAL 323
Cdd:TIGR02168 592 EILKNIEgflGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGyrIVTLDGDLVRPGGVITGgsaKTNSS 671
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 324 KSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHD 403
Cdd:TIGR02168 672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 404 LRNEVEKLRKEVCEREKAVEkhykslpgESSSKFHSQEQVVKGLTESA--SQEDLLLQKSNEKDLEAIqqncylMTAEEL 481
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLE--------EAEEELAEAEAEIEELEAQIeqLKEELKALREALDELRAE------LTLLNE 817
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 482 KFGSDGLITEKCSQQspdsklIFSKEKQQSEYEGLTGDLKTEQNVYAHLAKNLQDTDSKLQAELKRVLALRKQLEQDVLA 561
Cdd:TIGR02168 818 EAANLRERLESLERR------IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
|
570
....*....|....*...
gi 1958774896 562 YRNLQTALQEQLSEIRKR 579
Cdd:TIGR02168 892 LRSELEELSEELRELESK 909
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
62-637 |
2.58e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 62 DFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKKNI------ELKVEVESLKRELQERDQLLVKASKAVESLA 135
Cdd:TIGR02168 299 RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEleekleELKEELESLEAELEELEAELEELESRLEELE 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 136 EgggsEIQRVKEDARKKVQQvEELLTKRIHLLEEDVKAAQAELEKAFAGTETE---------KALRLSLESKLSAMKKMQ 206
Cdd:TIGR02168 379 E----QLETLRSKVAQLELQ-IASLNNEIERLEARLERLEDRRERLQQEIEELlkkleeaelKELQAELEELEEELEELQ 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 207 EGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVsSGELRGLSATLREEKERDAEE-RQKERNHFE 285
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQSGLSGILgVLSELISVD 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 286 ERI-QALQEDLREKEREIATEKKNSLKrdKAIQGLT---------MALKSKEKEESENCEAALAEKEALLAKLHSENVTK 355
Cdd:TIGR02168 533 EGYeAAIEAALGGRLQAVVVENLNAAK--KAIAFLKqnelgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 356 NTENHRLLRN-------VKKVTQELNDLKKEKL----------------------------RLERD--LEEAHREGNRGA 398
Cdd:TIGR02168 611 DPKLRKALSYllggvlvVDDLDNALELAKKLRPgyrivtldgdlvrpggvitggsaktnssILERRreIEELEEKIEELE 690
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 399 RTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPgESSSKFHSQEQVVKGLTESASQEDLLLQKSNEKDLEAIQQncyLMTA 478
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE---IEEL 766
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 479 EELKFGSDGLITEKCSQQSPDSKLIfskEKQQSEYEGLTGDLKTEQNVYAHLAKNLQDTDSKLQAELKRVLALRKQLEQd 558
Cdd:TIGR02168 767 EERLEEAEEELAEAEAEIEELEAQI---EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED- 842
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 559 vlayrnlqtaLQEQLSEIRKREEEpfsfYSDQTSYLSICLEEHSQfQLEHFS------QEEIKKKVIDLIQLVKDLHADN 632
Cdd:TIGR02168 843 ----------LEEQIEELSEDIES----LAAEIEELEELIEELES-ELEALLneraslEEALALLRSELEELSEELRELE 907
|
....*
gi 1958774896 633 QHLKK 637
Cdd:TIGR02168 908 SKRSE 912
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1357-1583 |
3.30e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 3.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1357 EKLRKQLERQGCETDQGSTNVSAYSSELhNSLTSEIQFLRKQNEALstmlEKGSKEKQKENEKLRESLARKTESLEHLQL 1436
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAEL-AELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1437 EYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQ 1516
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958774896 1517 ESRGEAcgggQKGQDPFSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQLSQGSKQAQEGALTLA 1583
Cdd:COG1196 390 EALRAA----AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
217-432 |
4.45e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 217 EEKDRLIEELKLSLKSKEALIQCLKEEKSQMaspdeNVSSGELRGLSATLREeKERDAEERQKERNHFEERIQALQEDLR 296
Cdd:TIGR02169 674 AELQRLRERLEGLKRELSSLQSELRRIENRL-----DELSQELSDASRKIGE-IEKEIEQLEQEEEKLKERLEELEEDLS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 297 EKEREIATEKKNSLKRDKAIQGLTMALkSKEKEESENCEAALA-----EKEALLAKLHSENVTKNTENHRLLRNVKKVTQ 371
Cdd:TIGR02169 748 SLEQEIENVKSELKELEARIEELEEDL-HKLEEALNDLEARLShsripEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958774896 372 ELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAV---EKHYKSLPGE 432
Cdd:TIGR02169 827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALrdlESRLGDLKKE 890
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
49-544 |
4.65e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 49 EEKVSPTRARNMKDFENQITELKK-ENFNLKLriyflEERIQQEFAGPTEHIYKKNIELKVEVESLKRELQErdqlLVKA 127
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEEAKKaEEAKKKA-----EEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADE----AKKA 1505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 128 SKAVESLAEGGGSEIQRVKEDARK--KVQQVEELLTKRIHLLEEDVKAAQaELEKAFAGTETEKALRLSlESKLSAMKKM 205
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKaeEAKKADEAKKAEEKKKADELKKAE-ELKKAEEKKKAEEAKKAE-EDKNMALRKA 1583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 206 QEgdlemtLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLR----EEKERDAEERQKER 281
Cdd:PTZ00121 1584 EE------AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKkkeaEEKKKAEELKKAEE 1657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 282 nhfEERIQALQEDLREKEREIATE---KKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTE 358
Cdd:PTZ00121 1658 ---ENKIKAAEEAKKAEEDKKKAEeakKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 359 NHRLLRNVKKVTQELNDLKKEKlrleRDLEEAHREGNRGARTIHDLRNEV--EKLRKEVCEREKAVEKHYKSLPGESSSk 436
Cdd:PTZ00121 1735 AKKEAEEDKKKAEEAKKDEEEK----KKIAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNFAN- 1809
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 437 fhsqeqvvkgLTESASQEDLLLQKSNEKDLEAIQQ-----NCYLMTAEEL---KFGSDGLITEKCSQQSPDSKLIFSKEK 508
Cdd:PTZ00121 1810 ----------IIEGGKEGNLVINDSKEMEDSAIKEvadskNMQLEEADAFekhKFNKNNENGEDGNKEADFNKEKDLKED 1879
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 1958774896 509 QQSEYEGL-------TGDLKTEQNVYAHLAKNLQDTDSKLQAE 544
Cdd:PTZ00121 1880 DEEEIEEAdeiekidKDDIEREIPNNNMAGKNNDIIDDKLDKD 1922
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
58-393 |
6.64e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 6.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 58 RNMKDFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEH------IYKKNIELKVEVESLKRELQERDQLLVKASKAV 131
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELsrqisaLRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 132 ESLAEGGGSEIQRVKEDARKKVQQVEEL--LTKRIHLLEEDVKAAQAEL--EKAFAGTETEKALRL---------SLESK 198
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIeqLKEELKALREALDELRAELtlLNEEAANLRERLESLerriaaterRLEDL 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 199 LSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSgELRGLSATLReEKERDAEERQ 278
Cdd:TIGR02168 844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE-ELRELESKRS-ELRRELEELR 921
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 279 KERNHFEERIQALQEDLREKEREIATEKKNSLkrdkaiqGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTE 358
Cdd:TIGR02168 922 EKLAQLELRLEGLEVRIDNLQERLSEEYSLTL-------EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEE 994
|
330 340 350
....*....|....*....|....*....|....*....
gi 1958774896 359 nhrlLRNVKK----VTQELNDLKKEKLRLERDLEEAHRE 393
Cdd:TIGR02168 995 ----YEELKErydfLTAQKEDLTEAKETLEEAIEEIDRE 1029
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
61-330 |
8.50e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 8.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 61 KDFENQITELKKENFNLKLRIYFLEERIQQEfagpTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVEslaegggs 140
Cdd:COG1196 256 EELEAELAELEAELEELRLELEELELELEEA----QAEEYELLAELARLEQDIARLEERRRELEERLEELEE-------- 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 141 EIQRVKEDARKKVQQVEELLTKRIhLLEEDVKAAQAELEKAfagTETEKALRLSLESKLSAMKKMQEGDLEMTLALEEKD 220
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELE-EAEEELEEAEAELAEA---EEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 221 RLIEELKLSLKSKEALIQCLKEEKSQMASPDENVssgelrglsATLREEKERDAEERQKERNHFEERIQALQEDLREKER 300
Cdd:COG1196 400 AQLEELEEAEEALLERLERLEEELEELEEALAEL---------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
|
250 260 270
....*....|....*....|....*....|
gi 1958774896 301 EIATEKKNSLKRDKAIQGLTMALKSKEKEE 330
Cdd:COG1196 471 EAALLEAALAELLEELAEAAARLLLLLEAE 500
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
97-591 |
8.76e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 8.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 97 EHIYKKNIELKVEVESLKRELQErdqlLVKASKAVESLAEGGGSEIQRVKEDARKkvqqveelLTKRIHLLEEDVKAAQA 176
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIERLEK----FIKRTENIEELIKEKEKELEEVLREINE--------ISSELPELREELEKLEK 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 177 ELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEMTLALEEKDRLIEELK------LSLKSKEALIQCLKEEKSQMASP 250
Cdd:PRK03918 229 EVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvkelKELKEKAEEYIKLSEFYEEYLDE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 251 DENVSSGELRglsatlREEKERDAEERQKERNHFEERIQALQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEE 330
Cdd:PRK03918 309 LREIEKRLSR------LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLT 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 331 SENCEAalAEKEALLAKLHSENVTKNTENhrLLRNVKKVTQELNDLKKEKLRLE----------RDLEEAHREG------ 394
Cdd:PRK03918 383 GLTPEK--LEKELEELEKAKEEIEEEISK--ITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKElleeyt 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 395 ---NRGARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSSKF-HSQEQVVKG-----LTESASQEDLLLQKSNEKD 465
Cdd:PRK03918 459 aelKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQlKELEEKLKKynleeLEKKAEEYEKLKEKLIKLK 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 466 LEAIQQNCYLMTAEELKFGSDGLITEKCSQQSPDSKLIFS-KEKQQSEYEGLTGDLKTEQNVYAHLAKnLQDTDSKLQAE 544
Cdd:PRK03918 539 GEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKElEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELERE 617
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1958774896 545 LKRVLALRKQLEQdvlAYRNLQTALQEqLSEIRKREEEPFSFYSDQT 591
Cdd:PRK03918 618 EKELKKLEEELDK---AFEELAETEKR-LEELRKELEELEKKYSEEE 660
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
61-469 |
2.45e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 2.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 61 KDFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKKNIELKVEVE-SLKRELQERDQLLVKASKAVESLAEGGG 139
Cdd:pfam02463 574 PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVvEGILKDTELTKLKESAKAKESGLRKGVS 653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 140 SEIqrvKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEMTLALEEK 219
Cdd:pfam02463 654 LEE---GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 220 DRLIEELKLSLKSKEALIQCLKEEKSQMAspdenvssgelrglsatlREEKERDAEERQKERNHFEERIQALQEDLREKE 299
Cdd:pfam02463 731 QDKINEELKLLKQKIDEEEEEEEKSRLKK------------------EEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 300 REIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKE 379
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 380 KLRLERDLEEAHREgnrgartihDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSSKFHSQEQVVKGLTESASQEDLLLQ 459
Cdd:pfam02463 873 LLKEEELEEQKLKD---------ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE 943
|
410
....*....|
gi 1958774896 460 KSNEKDLEAI 469
Cdd:pfam02463 944 EADEKEKEEN 953
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1332-1588 |
3.96e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.86 E-value: 3.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1332 QDLLMEHIQEIRTL---RKHLEESIKTNEKLRKQLERQGCETDqgstnvsayssELHNSLTSEIQFLRKQNEALSTMLEk 1408
Cdd:COG1196 287 QAEEYELLAELARLeqdIARLEERRRELEERLEELEEELAELE-----------EELEELEEELEELEEELEEAEEELE- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1409 gskEKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLL 1488
Cdd:COG1196 355 ---EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1489 QKDELLQSLQMELkvyEKLAEEHQKLQQESRGEAcgggqkgqdpfSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQL 1568
Cdd:COG1196 432 ELEEEEEEEEEAL---EEAAEEEAELEEEEEALL-----------ELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
250 260
....*....|....*....|
gi 1958774896 1569 SQGSKQAQEGALTLAVQALS 1588
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLA 517
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
140-397 |
5.33e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 5.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 140 SEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKafagtetekalrlsLESKLSAMKKmQEGDLEMTLALEEK 219
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA--------------LERRIAALAR-RIRALEQELAALEA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 220 DrlIEELKLSLKSKEALIQCLKEEKSQMAspDENVSSGELRGLSATLREEKERDAEERQKERNHFEERIQALQEDLREKE 299
Cdd:COG4942 84 E--LAELEKEIAELRAELEAQKEELAELL--RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 300 REIATEKKNSLKRDKAIQgltmALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKE 379
Cdd:COG4942 160 AELAALRAELEAERAELE----ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
250
....*....|....*...
gi 1958774896 380 KLRLERDLEEAHREGNRG 397
Cdd:COG4942 236 AAAAAERTPAAGFAALKG 253
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
217-581 |
6.71e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 6.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 217 EEKDRLIEE----LKLSLKSKEALiqclkeekSQMASPDENvssgeLRGLSATLRE-EKERDAEERQKERnhfEERIQAL 291
Cdd:TIGR02168 155 EERRAIFEEaagiSKYKERRKETE--------RKLERTREN-----LDRLEDILNElERQLKSLERQAEK---AERYKEL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 292 QEDLREKEREIATEKKNSLKRDKAiqgltmALKSKEKEESENCEAALAEKEALLAKLhsenVTKNTENHRLLRNVKKVTQ 371
Cdd:TIGR02168 219 KAELRELELALLVLRLEELREELE------ELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQK 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 372 ELNDLKKEKLRLERDLEEA-------HREGNRGARTIHDLRNEVEKLRKEVCEREKA---VEKHYKSLPGESSSKFHSQE 441
Cdd:TIGR02168 289 ELYALANEISRLEQQKQILrerlanlERQLEELEAQLEELESKLDELAEELAELEEKleeLKEELESLEAELEELEAELE 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 442 QVVKGLTESASQEDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKCSQQSPDSKLIFSKEKQqsEYEGLTGDLK 521
Cdd:TIGR02168 369 ELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELE 446
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 522 TEQNVYAHLAKNLQDTDSKLQAELKRVLALRKQLEQDVLAYRNLQTALQEQLSEIRKREE 581
Cdd:TIGR02168 447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
216-576 |
7.16e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 7.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 216 LEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDEnvSSGELRGLSATLREeKERDAEERQKERnhFEERIQALQEDL 295
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA--LLKEKREYEGYELL-KEKEALERQKEA--IERQLASLEEEL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 296 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELND 375
Cdd:TIGR02169 254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 376 LKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCErekaVEKHYKSLPGESSSKFHSQEQVVKGLTESASQED 455
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE----VDKEFAETRDELKDYREKLEKLKREINELKRELD 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 456 LLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKCSQQSPDSKLIFSKEKQQSEYEGLTGDLKTEQNvyahlakNLQ 535
Cdd:TIGR02169 410 RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD-------RVE 482
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1958774896 536 DTDSKLQAELKRVLALRKQLEQDVLAYRNLQTALQEQLSEI 576
Cdd:TIGR02169 483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
107-424 |
1.09e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 50.50 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 107 KVEVESLKRELQERDQLLVKASKAVESLaeggGSEIQRVKEDARKKVQQVEELLTKRIHLleedvKAAQAELEK-AFAGT 185
Cdd:pfam15921 488 KMTLESSERTVSDLTASLQEKERAIEAT----NAEITKLRSRVDLKLQELQHLKNEGDHL-----RNVQTECEAlKLQMA 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 186 ETEKA---LRLSLE--SKLSAMKKMQEGDLEMTLALEEK---DRLIE--ELKLSLKSKEALIQCLKEEKSQMASPDENVS 255
Cdd:pfam15921 559 EKDKVieiLRQQIEnmTQLVGQHGRTAGAMQVEKAQLEKeinDRRLElqEFKILKDKKDAKIRELEARVSDLELEKVKLV 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 256 SGELRGLSATLREEKERD-----AEERQKERNHFEERIQALQEDLREK--EREIATEK-KNSLKRDKA-IQGLTMALKSK 326
Cdd:pfam15921 639 NAGSERLRAVKDIKQERDqllneVKTSRNELNSLSEDYEVLKRNFRNKseEMETTTNKlKMQLKSAQSeLEQTRNTLKSM 718
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 327 EKEESENCEAALAEKEALLAKLHSENVTKnTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRN 406
Cdd:pfam15921 719 EGSDGHAMKVAMGMQKQITAKRGQIDALQ-SKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRS 797
|
330
....*....|....*...
gi 1958774896 407 EVEKLRKEVCEREKAVEK 424
Cdd:pfam15921 798 QERRLKEKVANMEVALDK 815
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
106-418 |
1.46e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.21 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 106 LKVEVESLKRELQERDQLLVKASKAVESLAEGGG---SEIQRVKEDARKKVQQVeELLTKRIHLLEEDVKAAQAELEKAf 182
Cdd:pfam10174 343 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKStlaGEIRDLKDMLDVKERKI-NVLQKKIENLQEQLRDKDKQLAGL- 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 183 agTETEKALRLSLESKLSAMKKMQEgdlemtlALEEKDRLIEELK--------LSLKSKEALIQCLKEEKSQMaspdeNV 254
Cdd:pfam10174 421 --KERVKSLQTDSSNTDTALTTLEE-------ALSEKERIIERLKeqreredrERLEELESLKKENKDLKEKV-----SA 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 255 SSGELRGLSATLREEKERDAEERQKernhfeeriqALQEDLREKEREIATEKknslKRDKAIQGLTMALKSKEKEESENC 334
Cdd:pfam10174 487 LQPELTEKESSLIDLKEHASSLASS----------GLKKDSKLKSLEIAVEQ----KKEECSKLENQLKKAHNAEEAVRT 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 335 EAALAEKEALL---AKLHSENVTK-NTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEK 410
Cdd:pfam10174 553 NPEINDRIRLLeqeVARYKEESGKaQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKK 632
|
....*...
gi 1958774896 411 LRKEVCER 418
Cdd:pfam10174 633 KGAQLLEE 640
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
1383-1518 |
1.86e-05 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 48.86 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1383 ELHNSLTSEIQFLRKQNEALSTMLEKGSKEKQKENEKLRESLARKTES-------LEHLQLEYASVREENERLRRDISEK 1455
Cdd:smart00787 151 ENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELedcdpteLDRAKEKLKKLLQEIMIKVKKLEEL 230
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958774896 1456 ERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDellqslQMELKVYEKLAEEHQKLQQES 1518
Cdd:smart00787 231 EEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCR------GFTFKEIEKLKEQLKLLQSLT 287
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
144-390 |
2.11e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 144 RVKEDARKKVQQVEELltKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLEsKLSAMKKMqegdlemtLALEEKDRLI 223
Cdd:COG4913 222 DTFEAADALVEHFDDL--ERAHEALEDAREQIELLEPIRELAERYAAARERLA-ELEYLRAA--------LRLWFAQRRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 224 EELklslkskEALIQCLKEEKSQMAspdenvssGELRGLSATLREEKERDAEERQKERNHFEERIQALQEDLREKEREIA 303
Cdd:COG4913 291 ELL-------EAELEELRAELARLE--------AELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 304 TEKKNSLKRDKAIQGLTMALKSKEK---EESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEK 380
Cdd:COG4913 356 ERERRRARLEALLAALGLPLPASAEefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
|
250
....*....|
gi 1958774896 381 LRLERDLEEA 390
Cdd:COG4913 436 SNIPARLLAL 445
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1340-1577 |
2.20e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1340 QEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELHnSLTSEIQFLRKQNEALSTMLEKGSKEK---QKE 1416
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIaqlSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1417 NEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKS----RQQLLLQKDE 1492
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANlrerLESLERRIAA 835
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1493 LLQSLQMELKVYEKLAEEHQKLQQESRgeacgggqKGQDPFSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQLSQGS 1572
Cdd:TIGR02168 836 TERRLEDLEEQIEELSEDIESLAAEIE--------ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
|
....*
gi 1958774896 1573 KQAQE 1577
Cdd:TIGR02168 908 SKRSE 912
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
58-344 |
2.42e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 2.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 58 RNMKDFENQITELKKENFNLKLRIYFLEERIQQefagptehiykknIELKV-EVESLKRELQERDQLLVKASKAVESLAE 136
Cdd:TIGR02168 239 EELEELQEELKEAEEELEELTAELQELEEKLEE-------------LRLEVsELEEEIEELQKELYALANEISRLEQQKQ 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 137 GGGSEIQRVKEDARKKVQQVEELLTKRIHLLEEdvkaaQAELEKAFAGTETEKAlrlSLESKLSAMKKMQEgdlEMTLAL 216
Cdd:TIGR02168 306 ILRERLANLERQLEELEAQLEELESKLDELAEE-----LAELEEKLEELKEELE---SLEAELEELEAELE---ELESRL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 217 EEKDRLIE-------ELKLSLKSKEALIQCLKEEKSQMA-----------SPDENVSSGELRGLSATLrEEKERDAEERQ 278
Cdd:TIGR02168 375 EELEEQLEtlrskvaQLELQIASLNNEIERLEARLERLEdrrerlqqeieELLKKLEEAELKELQAEL-EELEEELEELQ 453
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958774896 279 KERNHFEERIQALQEDLREKEREIaTEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEAL 344
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1340-1573 |
3.81e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 3.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1340 QEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELHNSLTSeiqflRKQNEALSTMLEKGSKEKQKENEK 1419
Cdd:TIGR02168 281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-----LDELAEELAELEEKLEELKEELES 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1420 LRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVC---SSLQELSRVQEEAKSRQQLLLQKDELLQS 1496
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIErleARLERLEDRRERLQQEIEELLKKLEEAEL 435
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958774896 1497 LQMELKVYEKLAEEHQKLQQESRGEAcgggqkgqdPFSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQLSQGSK 1573
Cdd:TIGR02168 436 KELQAELEELEEELEELQEELERLEE---------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1335-1517 |
5.11e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 5.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1335 LMEHIQEIRTLRKHLEESIKTNEKLRKQLERQgceTDQGSTNVSAYSSELhNSLTSEIQFLRKQNEALSTMLEKGSKE-- 1412
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERR---IAALARRIRALEQEL-AALEAELAELEKEIAELRAELEAQKEEla 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1413 -------KQKENEKLR-----ESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEA 1480
Cdd:COG4942 108 ellralyRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187
|
170 180 190
....*....|....*....|....*....|....*..
gi 1958774896 1481 KSRQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQE 1517
Cdd:COG4942 188 AALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1334-1516 |
6.41e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 6.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1334 LLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAysselhnsLTSEIQFLRKQNEALSTMLEKGSKEK 1413
Cdd:COG4717 68 LNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEE--------LREELEKLEKLLQLLPLYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1414 QKENEKLR-ESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLT-QEVCSSLQELSRVQEEAKSRQQLLLQKD 1491
Cdd:COG4717 140 ELAELPERlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQ 219
|
170 180
....*....|....*....|....*
gi 1958774896 1492 ELLQSLQMELKVYEKLAEEHQKLQQ 1516
Cdd:COG4717 220 EELEELEEELEQLENELEAAALEER 244
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
215-401 |
8.12e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.47 E-value: 8.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 215 ALEEKDRLIEELKLSLKS--KEALIQcLKEEKSQmaspdenvssgelrglsatLREEKERDAEERQKERNHFEERIQALQ 292
Cdd:PRK12704 36 AEEEAKRILEEAKKEAEAikKEALLE-AKEEIHK-------------------LRNEFEKELRERRNELQKLEKRLLQKE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 293 EDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEesenCEAALAEKEALLAKLhsENVTKNTENHRLLRNVKKvtqe 372
Cdd:PRK12704 96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEE----LEELIEEQLQELERI--SGLTAEEAKEILLEKVEE---- 165
|
170 180 190
....*....|....*....|....*....|
gi 1958774896 373 lnDLKKEKLRLERDLE-EAHREGNRGARTI 401
Cdd:PRK12704 166 --EARHEAAVLIKEIEeEAKEEADKKAKEI 193
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1332-1521 |
1.01e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1332 QDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELHN------SLTSEIQFLRKQNEALSTM 1405
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLlneeaaNLRERLESLERRIAATERR 839
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1406 LEKGSKEKQKENE----------KLRESLARKTESLEHLQLEYASVREENERLR-------RDISEKERQNQQLTQEVCS 1468
Cdd:TIGR02168 840 LEDLEEQIEELSEdieslaaeieELEELIEELESELEALLNERASLEEALALLRseleelsEELRELESKRSELRRELEE 919
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1958774896 1469 SLQELSRVQEE-AKSRQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQESRGE 1521
Cdd:TIGR02168 920 LREKLAQLELRlEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1393-1510 |
1.17e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1393 QFLRKQNEALSTMLEKGSKEKQKENEKLR--ESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEvcsSL 1470
Cdd:PRK12704 65 EIHKLRNEFEKELRERRNELQKLEKRLLQkeENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE---QL 141
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1958774896 1471 QELSRV----QEEAKsrqQLLLQ--KDELLQSLQMELKVYEKLAEE 1510
Cdd:PRK12704 142 QELERIsgltAEEAK---EILLEkvEEEARHEAAVLIKEIEEEAKE 184
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
87-637 |
1.26e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.02 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 87 RIQQEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEGGGSEIQRVKEDARKKVQQVEELLTKR--I 164
Cdd:pfam05483 78 RLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRhlC 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 165 HLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMqegdLEMTLALEEKDRLieELKLSLKSKEALIQCLKEEK 244
Cdd:pfam05483 158 NLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILA----FEELRVQAENARL--EMHFKLKEDHEKIQHLEEEY 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 245 SQMASPDENVSSgeLRGLSATLREEKERD----AEERQKERNHFEERIQALQEDLREK------------------EREI 302
Cdd:pfam05483 232 KKEINDKEKQVS--LLLIQITEKENKMKDltflLEESRDKANQLEEKTKLQDENLKELiekkdhltkeledikmslQRSM 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 303 ATEKknSLKRDKAIQGLTMALKSKEKE-ESENCEAALAEKEALLAKLHSENVTKN----TENHRLLRN----------VK 367
Cdd:pfam05483 310 STQK--ALEEDLQIATKTICQLTEEKEaQMEELNKAKAAHSFVVTEFEATTCSLEellrTEQQRLEKNedqlkiitmeLQ 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 368 KVTQELNDLKKEKLRLERDLEEAHREGNRgARTIHDLRNEVEKLRKEVcereKAVEKHYKSLPGESSSKFHSQEQVVKGL 447
Cdd:pfam05483 388 KKSSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKIAEEL----KGKEQELIFLLQAREKEIHDLEIQLTAI 462
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 448 TESASQ-----EDLLLQKSNEKdleaiqqncylMTAEELKFGSDGLITEKCSQQSPDSKLIFSKEKQQseyEGLTGDLKT 522
Cdd:pfam05483 463 KTSEEHylkevEDLKTELEKEK-----------LKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ---EDIINCKKQ 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 523 EQNVYAHLaKNLQDTDSKLQAELKRVlalRKQLEQDvlayrnlqtaLQEQLSEIRKREEEPFSFYSDqtsylsiCLEEHS 602
Cdd:pfam05483 529 EERMLKQI-ENLEEKEMNLRDELESV---REEFIQK----------GDEVKCKLDKSEENARSIEYE-------VLKKEK 587
|
570 580 590
....*....|....*....|....*....|....*
gi 1958774896 603 QFQLEHFSQEEIKKKVIDLIQLVKDLHADNQHLKK 637
Cdd:pfam05483 588 QMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
211-545 |
1.35e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.89 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 211 EMTLALEEKDRLIEELKLSLKSKEaliqclKEEKSQMaspdenvssgELRGLSATLREEKERDAEERQkeRNHFEERIQA 290
Cdd:pfam02463 180 EETENLAELIIDLEELKLQELKLK------EQAKKAL----------EYYQLKEKLELEEEYLLYLDY--LKLNEERIDL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 291 LQEDLREKEREIATEKKNSLKRDKAIQgLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVT 370
Cdd:pfam02463 242 LQELLRDEQEEIESSKQEIEKEEEKLA-QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 371 QELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSS-----KFHSQEQVVK 445
Cdd:pfam02463 321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERlssaaKLKEEELELK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 446 GLTESASQEDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKCSQQSpDSKLIFSKEKQQSEYEGLTGDLKTEQN 525
Cdd:pfam02463 401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEE-LEKQELKLLKDELELKKSEDLLKETQL 479
|
330 340
....*....|....*....|
gi 1958774896 526 VYAHLAKNLQDTDSKLQAEL 545
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERS 499
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
86-329 |
1.62e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 46.74 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 86 ERIQQEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEGGGS----------EIQRVKEDARK---- 151
Cdd:pfam10174 460 EREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKkdsklksleiAVEQKKEECSKlenq 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 152 --KVQQVEEL------LTKRIHLLEEDVK-------AAQAELEK---AFAGTETEKALRLSLESKLSAMKKMQEGDLEMT 213
Cdd:pfam10174 540 lkKAHNAEEAvrtnpeINDRIRLLEQEVArykeesgKAQAEVERllgILREVENEKNDKDKKIAELESLTLRQMKEQNKK 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 214 LA------LEEKDRLIEELKLSLKSKEALIQC-----LKEEKSQMASPDENVSSGELRgLSATLREEKERDA---EERQK 279
Cdd:pfam10174 620 VAnikhgqQEMKKKGAQLLEEARRREDNLADNsqqlqLEELMGALEKTRQELDATKAR-LSSTQQSLAEKDGhltNLRAE 698
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1958774896 280 ERNHFEERIQALQEDL----REKEREIATEKKNSLKRDKAiQGLTMALKsKEKE 329
Cdd:pfam10174 699 RRKQLEEILEMKQEALlaaiSEKDANIALLELSSSKKKKT-QEEVMALK-REKD 750
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
64-429 |
1.80e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 64 ENQITELKKENFNLKLRIYFLEERIQ-QEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLvkaskaveslaegggSEI 142
Cdd:COG4717 101 EEELEELEAELEELREELEKLEKLLQlLPLYQELEALEAELAELPERLEELEERLEELRELE---------------EEL 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 143 QRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKmQEGDLEMTLALEEKDRL 222
Cdd:COG4717 166 EELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE-ELEQLENELEAAALEER 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 223 IEELKLSLKSKEALIQCLKEEKSQMASPDEN------VSSGELRGLSATLREEKERDAEERQKERNHFEERI--QALQED 294
Cdd:COG4717 245 LKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELeeEELEEL 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 295 LREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESE-NCEAALAEKEALLAKLHSENVTKntenhrlLRNVKKVTQEL 373
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAEAGVEDEEE-------LRAALEQAEEY 397
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958774896 374 NDLKKEKLRLERDLEEAHREGNRGARTI--HDLRNEVEKLRKEVCEREKAVEKHYKSL 429
Cdd:COG4717 398 QELKEELEELEEQLEELLGELEELLEALdeEELEEELEELEEELEELEEELEELREEL 455
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
65-415 |
2.20e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 65 NQITELKKENFNLKLRIYFLE-ERIQQEFagptEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEGGGS--- 140
Cdd:PRK03918 365 EEAKAKKEELERLKKRLTGLTpEKLEKEL----EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpv 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 141 --------EIQRVKEDARKKVQQVEELLtKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEm 212
Cdd:PRK03918 441 cgrelteeHRKELLEEYTAELKRIEKEL-KEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLE- 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 213 tlALEEKDRLIEELKLSLKSKEALIQCLKEEKSQmaspdENVSSGELRGLSATLREEKERDAEERQKERNHFEERIQALQ 292
Cdd:PRK03918 519 --ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK-----LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELE 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 293 EDLREKER--EIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRN----- 365
Cdd:PRK03918 592 ERLKELEPfyNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREeylel 671
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958774896 366 ------VKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDL---RNEVEKLRKEV 415
Cdd:PRK03918 672 srelagLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLekaLERVEELREKV 730
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1411-1583 |
2.30e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1411 KEKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQ-EEAKSRQQLLLQ 1489
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEkEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1490 KDEL---LQSLQM---------------------ELKVYEKLAEEHQKLQQEsrgeacgggqkgqdpfsnLHGLLKEIQV 1545
Cdd:COG4942 103 KEELaelLRALYRlgrqpplalllspedfldavrRLQYLKYLAPARREQAEE------------------LRADLAELAA 164
|
170 180 190
....*....|....*....|....*....|....*...
gi 1958774896 1546 LRDQAERSIQTNNTLKSKLEKQLSQGSKQAQEGALTLA 1583
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLA 202
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
64-389 |
2.60e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.08 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 64 ENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAE-----GG 138
Cdd:COG1196 446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglaGA 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 139 GSEIQRVKEDARKKVQQVEELLTKRIHL-LEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEMTLALE 217
Cdd:COG1196 526 VAVLIGVEAAYEAALEAALAAALQNIVVeDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 218 EKDRLiEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSA--TLREEKERDAEERQKERNHFEERIQALQEDL 295
Cdd:COG1196 606 SDLRE-ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 296 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELND 375
Cdd:COG1196 685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764
|
330
....*....|....
gi 1958774896 376 LKKEKLRLERDLEE 389
Cdd:COG1196 765 LERELERLEREIEA 778
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
56-639 |
2.68e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.78 E-value: 2.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 56 RARNMKDFENQITELKKENFNLKLRIYFLEERIQQ-----EFAGPTEHIYKKNI-ELKVEVESLKRELQERDQLLVKASK 129
Cdd:TIGR04523 66 DEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKlnsdlSKINSEIKNDKEQKnKLEVELNKLEKQKKENKKNIDKFLT 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 130 AVESLAegggSEIQRVKEDARKKVQQVEELLTKRIHLLEE---------DVKAAQAELEKAFAGTETEKALRLSLESKLS 200
Cdd:TIGR04523 146 EIKKKE----KELEKLNNKYNDLKKQKEELENELNLLEKEklniqknidKIKNKLLKLELLLSNLKKKIQKNKSLESQIS 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 201 AMKKMQEgdlEMTLALEEKDRLIEELKLSLKSKEALIQCLKEE----KSQMASPDENV--SSGELRGLSATLREEK-ERD 273
Cdd:TIGR04523 222 ELKKQNN---QLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEqnkiKKQLSEKQKELeqNNKKIKELEKQLNQLKsEIS 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 274 AEERQKErnhfEERIQALQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKE----ESENCE--AALAEKEALLAK 347
Cdd:TIGR04523 299 DLNNQKE----QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEltnsESENSEkqRELEEKQNEIEK 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 348 LHSENVTKNTENHRL----------LRNVKKVTQELND----LKKEKLRLERDLEEAHREGNRGARTIHDLRNEV---EK 410
Cdd:TIGR04523 375 LKKENQSYKQEIKNLesqindleskIQNQEKLNQQKDEqikkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDsvkEL 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 411 LRKEVCEREKAVEKHYKSLPGESSSKFHSQEQVVKGLTESASQEDLLlqKSNEKDLEaiQQNCYLMT-AEELKFGSDGLI 489
Cdd:TIGR04523 455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL--NEEKKELE--EKVKDLTKkISSLKEKIEKLE 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 490 TEKCSQQSPDSKLifsKEKQQSEYEGLTGD-LKTEQNVY-------AHLAKNLQDTDSKLQAELKRVLALRKQLEQDVLA 561
Cdd:TIGR04523 531 SEKKEKESKISDL---EDELNKDDFELKKEnLEKEIDEKnkeieelKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEE 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 562 YRNLQTALQEQLSEIRKREEEPFSFYSDQTSYLSICLEEHSQFQLE-----------HFSQEEIKKKVIDLIQLVKD-LH 629
Cdd:TIGR04523 608 KEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETikeirnkwpeiIKKIKESKTKIDDIIELMKDwLK 687
|
650
....*....|
gi 1958774896 630 ADNQHLKKTI 639
Cdd:TIGR04523 688 ELSLHYKKYI 697
|
|
| DUF4175 |
pfam13779 |
Domain of unknown function (DUF4175); |
1395-1555 |
2.98e-04 |
|
Domain of unknown function (DUF4175);
Pssm-ID: 463981 [Multi-domain] Cd Length: 833 Bit Score: 45.75 E-value: 2.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1395 LRKQNEALSTMLEKGS--KEKQKENEKLRESLARKTESLEhlqleyasvreenERLRRDISEKERQNQQLTQEVcsSLQE 1472
Cdd:pfam13779 491 LRAAQERLSEALERGAsdEEIAKLMQELREALDDYMQALA-------------EQAQQNPQDLQQPDDPNAQEM--TQQD 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1473 LS----RVQEEAKS-----RQQLLLQKDELLQSLQMelkvyeklaEEHQKLQQESRGEacggGQKGQDpfsNLHGLLKEI 1543
Cdd:pfam13779 556 LQrmldRIEELARSgrraeAQQMLSQLQQMLENLQA---------GQPQQQQQQGQSE----MQQAMD---ELGDLLREQ 619
|
170
....*....|..
gi 1958774896 1544 QVLRDQAERSIQ 1555
Cdd:pfam13779 620 QQLLDETFRQLQ 631
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
86-332 |
3.09e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.88 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 86 ERIQQEFAGP------TEHIYKKNIELKVEVESLKRELQERDQllvkasKAVESLAEGGGSEIQRVKEDARKKVQQVEel 159
Cdd:pfam17380 392 ERVRQELEAArkvkilEEERQRKIQQQKVEMEQIRAEQEEARQ------REVRRLEEERAREMERVRLEEQERQQQVE-- 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 160 ltkRIHLLEEDVKAAQAELEKafagtETEKALRLSLESKLSAMKKMQegdlemtlalEEKDRLIEElklslKSKEALIQC 239
Cdd:pfam17380 464 ---RLRQQEEERKRKKLELEK-----EKRDRKRAEEQRRKILEKELE----------ERKQAMIEE-----ERKRKLLEK 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 240 LKEEKSqmaspdenvssgelrglSATLREEKERDAEERQKERNHFEERIQaLQEDLRekereIATEKKNSLKRDKAIQGL 319
Cdd:pfam17380 521 EMEERQ-----------------KAIYEEERRREAEEERRKQQEMEERRR-IQEQMR-----KATEERSRLEAMEREREM 577
|
250
....*....|...
gi 1958774896 320 TMALKSKEKEESE 332
Cdd:pfam17380 578 MRQIVESEKARAE 590
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
221-642 |
3.31e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.73 E-value: 3.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 221 RLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEERQKERN-------HFEERIQALQE 293
Cdd:pfam02463 123 ELLESQGISPEAYNFLVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENlaeliidLEELKLQELKL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 294 DLREKEREIATEKKNSLKRDKAIQgLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQEL 373
Cdd:pfam02463 203 KEQAKKALEYYQLKEKLELEEEYL-LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 374 NDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAVEKHYkslpgESSSKFHSQEQVVKGLTESASQ 453
Cdd:pfam02463 282 KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEK-----EEIEELEKELKELEIKREAEEE 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 454 EDLLLQKSNEKDLEAIQQNCYLMTAEELKFGSDGLITEKcsQQSPDSKLIFSKEKQQSEYEGLTGDLKTEQNVYAHLAKN 533
Cdd:pfam02463 357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE--ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 534 LQdtdsKLQAELKRVLALRKQLEQDVLAYRNLQTALQEQLSEIRKREEEPFSFYSDQTSYLSICLEEHSQFQLEHfsQEE 613
Cdd:pfam02463 435 EE----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKA--RSG 508
|
410 420
....*....|....*....|....*....
gi 1958774896 614 IKKKVIDLIQLVKDLHADNQHLKKTIFDI 642
Cdd:pfam02463 509 LKVLLALIKDGVGGRIISAHGRLGDLGVA 537
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1351-1577 |
3.45e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.40 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1351 ESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELHN---SLTSEIQFLRKQNEALSTMLEKGSKEK---QKENEKLRESL 1424
Cdd:TIGR04523 117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKeleKLNNKYNDLKKQKEELENELNLLEKEKlniQKNIDKIKNKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1425 ARKTESLEHLQleyaSVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQ-KDEL------LQSL 1497
Cdd:TIGR04523 197 LKLELLLSNLK----KKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQlKDEQnkikkqLSEK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1498 QMELKVYEKLAEEHQKLQQESRGEACG-GGQKGQDPFSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQLSQGSKQAQ 1576
Cdd:TIGR04523 273 QKELEQNNKKIKELEKQLNQLKSEISDlNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELT 352
|
.
gi 1958774896 1577 E 1577
Cdd:TIGR04523 353 N 353
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-413 |
3.58e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 45.62 E-value: 3.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 252 ENVSSGELRGLS--ATLREEKErdaEERQKERNHFEERIQALQEDLREKEREIAtekknslKRDKAIQGLtmalkskeKE 329
Cdd:COG2433 366 DEVKARVIRGLSieEALEELIE---KELPEEEPEAEREKEHEERELTEEEEEIR-------RLEEQVERL--------EA 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 330 ESENCEAALAEKEALLAKLHSENVTKNTENHRLLRNvkkvTQELNDLKKEKLRLERDLEEAHREgnrgartIHDLRNEVE 409
Cdd:COG2433 428 EVEELEAELEEKDERIERLERELSEARSEERREIRK----DREISRLDREIERLERELEEERER-------IEELKRKLE 496
|
....
gi 1958774896 410 KLRK 413
Cdd:COG2433 497 RLKE 500
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
49-330 |
4.02e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 4.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 49 EEKVSPTRARNMKDFENQITELKKENFNLKLRIYFLEERIQQEfagptehIYKKNIELKVEVESLKRELQERDQLLVKAS 128
Cdd:pfam02463 749 EEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE-------KEEKLKAQEEELRALEEELKEEAELLEEEQ 821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 129 KAVESLAEGGGSEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAMKKMQEG 208
Cdd:pfam02463 822 LLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKE 901
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 209 DLEMTLALEEKDRLIEELKLSlKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEERQKERNHFEERI 288
Cdd:pfam02463 902 LEEESQKLNLLEEKENEIEER-IKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAI 980
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1958774896 289 QALQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEE 330
Cdd:pfam02463 981 EEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
46-341 |
4.34e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 45.39 E-value: 4.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 46 IMSEEKVSPTRARNMK--DFENQITELKKENFNlklRIYFLEERIQQEFAGPTEHiykkniELKVEVESLKRELQERDQL 123
Cdd:NF033838 70 ILSEIQKSLDKRKHTQnvALNKKLSDIKTEYLY---ELNVLKEKSEAELTSKTKK------ELDAAFEQFKKDTLEPGKK 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 124 LVKASKAVEslaEGGGSEIQRVKEDARKKVQQVEEllTKRIHLLEEDVKAAQAELE------KAFAGTETEKALRLSLES 197
Cdd:NF033838 141 VAEATKKVE---EAEKKAKDQKEEDRRNYPTNTYK--TLELEIAESDVEVKKAELElvkeeaKEPRDEEKIKQAKAKVES 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 198 KLSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKS--------QMASPD--EN------VSSGELRG 261
Cdd:NF033838 216 KKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRrakrgvlgEPATPDkkENdakssdSSVGEETL 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 262 LSATLREEK-----ERDAEERQKE---------RNH-------FEERIQALQEDLREKEREIATEKKNSLKRDKAIQglt 320
Cdd:NF033838 296 PSPSLKPEKkvaeaEKKVEEAKKKakdqkeedrRNYptntyktLELEIAESDVKVKEAELELVKEEAKEPRNEEKIK--- 372
|
330 340
....*....|....*....|.
gi 1958774896 321 malKSKEKEESENCEAALAEK 341
Cdd:NF033838 373 ---QAKAKVESKKAEATRLEK 390
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1332-1503 |
5.78e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 5.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1332 QDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAysSELHNSLTSEIQFLRKQNEALSTMLEKGS- 1410
Cdd:COG3206 214 AKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ--SPVIQQLRAQLAELEAELAELSARYTPNHp 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1411 --KEKQKENEKLRESLARKTES-LEHLQLEYASVREENERLRRDISEKERQNQQLTQevcsSLQELSRVQEEAKSRQQLL 1487
Cdd:COG3206 292 dvIALRAQIAALRAQLQQEAQRiLASLEAELEALQAREASLQAQLAQLEARLAELPE----LEAELRRLEREVEVARELY 367
|
170
....*....|....*.
gi 1958774896 1488 lqkDELLQSLQmELKV 1503
Cdd:COG3206 368 ---ESLLQRLE-EARL 379
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1340-1487 |
5.95e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 5.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1340 QEIRTLRKHLEESIKTNEKLRKQLERQgcETDQGSTNVSAYSSELHNSLT------------SEIQFLRKQNEALSTMLE 1407
Cdd:COG4942 76 QELAALEAELAELEKEIAELRAELEAQ--KEELAELLRALYRLGRQPPLAlllspedfldavRRLQYLKYLAPARREQAE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1408 KgSKEKQKENEKLRESLARKTESLEHLQleyASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLL 1487
Cdd:COG4942 154 E-LRADLAELAALRAELEAERAELEALL---AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1371-1600 |
6.07e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 6.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1371 DQGSTNVSAYSSELHNsLTSEIQFLRKQNEALS---TMLEKGSKEKQKENEKLRESLARKTESLEHLQLEYASVREENER 1447
Cdd:TIGR02168 666 AKTNSSILERRREIEE-LEEKIEELEEKIAELEkalAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1448 LRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQESRGEACGGGQ 1527
Cdd:TIGR02168 745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1528 KGQDPFSNLHGLLKEIQVLRDQAER----------SIQTNNTLKSKLEKQLSQGSKQAQEGALTLAVQALSVTEWSLQLD 1597
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEElsedieslaaEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
...
gi 1958774896 1598 KHD 1600
Cdd:TIGR02168 905 ELE 907
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
56-429 |
6.37e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 6.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 56 RARNMKDFENQITELKKENFNLKLRIYFLEERIQQEFagptehiyKKNIELKVEVESLKRELQERDQLLVKASKAVESLA 135
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALL--------ERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 136 EGGGSEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEKAfAGTETEKALRLSLESKLSAMKKMQEGDLEMTLA 215
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 216 LEEKD----------------------------RLIEELKLSLKSKEALIQCLKEEKSqmASPDENVSSGELRGLSATLR 267
Cdd:COG1196 528 VLIGVeaayeaaleaalaaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIRAR--AALAAALARGAIGAAVDLVA 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 268 EEKERDAEERQKERNHFEERIQA---LQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAA--LAEKE 342
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVaarLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEaeLEELA 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 343 ALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAV 422
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
|
....*..
gi 1958774896 423 EKHYKSL 429
Cdd:COG1196 766 ERELERL 772
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1332-1519 |
7.36e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 7.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1332 QDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERqgcetdqgSTNVSAYSSELHNSLTSEIQFLRKQNEALSTMLEKGSK 1411
Cdd:TIGR02169 786 ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ--------KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1412 EKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKD 1491
Cdd:TIGR02169 858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
170 180 190
....*....|....*....|....*....|.
gi 1958774896 1492 ELLQSLQ---MELKVYEKLAEEHQKLQQESR 1519
Cdd:TIGR02169 938 DPKGEDEeipEEELSLEDVQAELQRVEEEIR 968
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
215-422 |
7.46e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 7.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 215 ALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASpdenvssgELRGLSATLrEEKERDAEERQKERNHFEERIQALQED 294
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--------QLAALERRI-AALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 295 LREKEREIATEKKNSLKRDKAIQ------GLTMALKSKEKEES--------------ENCEAALAEKEALLAKLHSENVT 354
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYrlgrqpPLALLLSPEDFLDAvrrlqylkylaparREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958774896 355 KNTENHRLLRNVKKVTQELNDLKKEKL----RLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAV 422
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQkllaRLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
141-387 |
7.86e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 44.34 E-value: 7.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 141 EIQRVKEDARKKVQQVEelltkRIHLLEEDVKAAQAELEKAFA--------GTETEKAL-RLSLESKLSAMKKMQEGDLE 211
Cdd:pfam17380 297 EQERLRQEKEEKAREVE-----RRRKLEEAEKARQAEMDRQAAiyaeqermAMERERELeRIRQEERKRELERIRQEEIA 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 212 MT---------LALEEK---DRLIEEL------KLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKER- 272
Cdd:pfam17380 372 MEisrmrelerLQMERQqknERVRQELeaarkvKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERv 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 273 ----------------DAEERQKERNHF--EERIQALQEDLREK--EREIATEKKNSLKRDKAIQGLTMALKSKEKEESE 332
Cdd:pfam17380 452 rleeqerqqqverlrqQEEERKRKKLELekEKRDRKRAEEQRRKilEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1958774896 333 NCEAALAEKEALLAKlhsenvtKNTENHRLLRNVKKVTQELNDLkkEKLRLERDL 387
Cdd:pfam17380 532 EERRREAEEERRKQQ-------EMEERRRIQEQMRKATEERSRL--EAMEREREM 577
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1325-1512 |
9.97e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 9.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1325 TIASRFPQDLLMEHIQEirTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELHNSLTSEIQFLRKQNEalst 1404
Cdd:pfam17380 283 AVSERQQQEKFEKMEQE--RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE---- 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1405 mlekgskEKQKENEKLR-ESLA---RKTESLEHLQLEYasvREENERLRRD--------ISEKERQNQQLTQEVcsSLQE 1472
Cdd:pfam17380 357 -------ERKRELERIRqEEIAmeiSRMRELERLQMER---QQKNERVRQEleaarkvkILEEERQRKIQQQKV--EMEQ 424
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1958774896 1473 LSRVQEEAKSRQqllLQKDELLQSLQMELKVYEKLAEEHQ 1512
Cdd:pfam17380 425 IRAEQEEARQRE---VRRLEEERAREMERVRLEEQERQQQ 461
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
64-463 |
1.02e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.19 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 64 ENQITELKKENFNLKLRIYFLEERIQQEfaGPTEHIYKKNIELKVEVESLKRELQERDQLLVK-----ASKAVESLAEGG 138
Cdd:TIGR00618 448 TCTAQCEKLEKIHLQESAQSLKEREQQL--QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGscihpNPARQDIDNPGP 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 139 GSEIQRVKEDARKKVQQVEELLTkriHLLEEDVKAAQAELEKAFAGTETEKAL-RLSLESKLSAMKKMQEGDL---EMTL 214
Cdd:TIGR00618 526 LTRRMQRGEQTYAQLETSEEDVY---HQLTSERKQRASLKEQMQEIQQSFSILtQCDNRSKEDIPNLQNITVRlqdLTEK 602
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 215 ALEEKDRLIEELKLSLKSKEALI-------------QCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEERQKER 281
Cdd:TIGR00618 603 LSEAEDMLACEQHALLRKLQPEQdlqdvrlhlqqcsQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL 682
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 282 NHFEERIQALQEDLR------EKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTK 355
Cdd:TIGR00618 683 QKMQSEKEQLTYWKEmlaqcqTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 356 NTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSS 435
Cdd:TIGR00618 763 HFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA 842
|
410 420
....*....|....*....|....*...
gi 1958774896 436 KFHSQEQVVKGLTESASQEDLLLQKSNE 463
Cdd:TIGR00618 843 TLGEITHQLLKYEECSKQLAQLTQEQAK 870
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
64-486 |
1.02e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.06 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 64 ENQITELKKENFNLKLRIYFLEERIQQEFAGPTEhiyKKNIELKVEVESLKRELQErdqllvKASKAVESLaegggseiQ 143
Cdd:pfam12128 429 EAGKLEFNEEEYRLKSRLGELKLRLNQATATPEL---LLQLENFDERIERAREEQE------AANAEVERL--------Q 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 144 RVKEDARKKVQQVEELLtKRIHLLEEDVKAAQAELEK----------AFAGTE-------------TEKALRLSLESKLS 200
Cdd:pfam12128 492 SELRQARKRRDQASEAL-RQASRRLEERQSALDELELqlfpqagtllHFLRKEapdweqsigkvisPELLHRTDLDPEVW 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 201 AMKKMQEGDL-EMTLALEEKD------------RLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSA--T 265
Cdd:pfam12128 571 DGSVGGELNLyGVKLDLKRIDvpewaaseeelrERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTAlkN 650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 266 LREEKERDAEERQKERNHFEERIQALQEDLREKEREIATEKKNSLKRDKA----IQG----LTMALKSKEKEESENCEAA 337
Cdd:pfam12128 651 ARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAwleeQKEqkreARTEKQAYWQVVEGALDAQ 730
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 338 LA----EKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGAR-------------- 399
Cdd:pfam12128 731 LAllkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfdwyqetwlqrrp 810
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 400 ----TIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESsskfHSQEQVVKGLTESASQEDLLLQKSNEKDLEAIQQNCYL 475
Cdd:pfam12128 811 rlatQLSNIERAISELQQQLARLIADTKLRRAKLEMER----KASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQG 886
|
490
....*....|.
gi 1958774896 476 MTAEELKFGSD 486
Cdd:pfam12128 887 SIGERLAQLED 897
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
56-373 |
1.05e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 56 RARNMKDFENQITELKKenfnlKLRIYFLE--ERIQQEFagptEHIYKKNIELKVEVESLKRELqERDQLLVKASKAVES 133
Cdd:PRK03918 494 ELIKLKELAEQLKELEE-----KLKKYNLEelEKKAEEY----EKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEK 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 134 laegggsEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKaaqaELEKAFAGTETEKALRLSLESKLSAMKKMQEgDLEMT 213
Cdd:PRK03918 564 -------KLDELEEELAELLKELEELGFESVEELEERLK----ELEPFYNEYLELKDAEKELEREEKELKKLEE-ELDKA 631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 214 LA-LEEKDRLIEELKLSLkskealiqclkEEKSQMASPDENvssgelrglsatlrEEKERDAEERQKERNHFEERIQALQ 292
Cdd:PRK03918 632 FEeLAETEKRLEELRKEL-----------EELEKKYSEEEY--------------EELREEYLELSRELAGLRAELEELE 686
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 293 EDLREKEREIATEKKNSLKRDKAiqgltmalkskeKEESENCEAALAEKEALLAKLHSenvTKNTENHRLLRNVKKVTQE 372
Cdd:PRK03918 687 KRREEIKKTLEKLKEELEEREKA------------KKELEKLEKALERVEELREKVKK---YKALLKERALSKVGEIASE 751
|
.
gi 1958774896 373 L 373
Cdd:PRK03918 752 I 752
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
267-478 |
1.22e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 267 REEKERDAEERQKERNHFEERIQALQEDLREKeREIATEKKNSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLA 346
Cdd:pfam07888 61 KERYKRDREQWERQRRELESRVAELKEELRQS-REKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIK 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 347 KLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRN-------EVEKLRKEVCE-R 418
Cdd:pfam07888 140 TLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNslaqrdtQVLQLQDTITTlT 219
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958774896 419 EKAVEKHYKSLPGESSSK--------FHSQEQVVKGLTES----ASQEDLLLQKSNEKDLEAIQQNCYLMTA 478
Cdd:pfam07888 220 QKLTTAHRKEAENEALLEelrslqerLNASERKVEGLGEElssmAAQRDRTQAELHQARLQAAQLTLQLADA 291
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
218-415 |
1.55e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 218 EKDRLIEELKLSL---KSKEALIQCLKEEksqmASPDENVSSGELRGLSATLREEKERDAEERQKERNHFEERIQALQED 294
Cdd:COG2433 360 PPDVDRDEVKARVirgLSIEEALEELIEK----ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAE 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 295 LREKEREIAtEKKNSLKRdkaiqgltmaLKSKEKEEsenceaalAEKEALLAKLhsenvtkNTENHRLLRNVKKVTQELN 374
Cdd:COG2433 436 LEEKDERIE-RLERELSE----------ARSEERRE--------IRKDREISRL-------DREIERLERELEEERERIE 489
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1958774896 375 DLKKEKLRLERDLEEAHREGNRGARTIHDL-RNEVEKLRKEV 415
Cdd:COG2433 490 ELKRKLERLKELWKLEHSGELVPVKVVEKFtKEAIRRLEEEY 531
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1335-1517 |
1.88e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1335 LMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELhNSLTSEIQFLRKQNEALSTMLekgsKEKQ 1414
Cdd:TIGR02168 735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI-EELEAQIEQLKEELKALREAL----DELR 809
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1415 KENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDELL 1494
Cdd:TIGR02168 810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889
|
170 180
....*....|....*....|...
gi 1958774896 1495 QSLQMElkvYEKLAEEHQKLQQE 1517
Cdd:TIGR02168 890 ALLRSE---LEELSEELRELESK 909
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
266-582 |
1.90e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.39 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 266 LREEKERDAE--ERQKERnhfEERIQALQEDLREKEREIAtekknsLKRDKAIQgltmALKSKEKEESENCEAALAEKEA 343
Cdd:COG1196 194 ILGELERQLEplERQAEK---AERYRELKEELKELEAELL------LLKLRELE----AELEELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 344 LLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHREGNRGARTIHDLRNEVEKLRKEvcerekave 423
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE--------- 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 424 khykslpgessskfhsQEQVVKGLTESASQEDLLLQKSNEKDLEAIQQncylmtAEELKfgsdglitEKCSQQSPDSKLI 503
Cdd:COG1196 332 ----------------LEELEEELEELEEELEEAEEELEEAEAELAEA------EEALL--------EAEAELAEAEEEL 381
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958774896 504 FSKEKQQSEyegltgdLKTEQNVYAHLAKNLQDTDSKLQAELKRVLALRKQLEQDvlayrnlQTALQEQLSEIRKREEE 582
Cdd:COG1196 382 EELAEELLE-------ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA-------LAELEEEEEEEEEALEE 446
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1335-1520 |
1.91e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1335 LMEHIQEIRTLRKHLEESIKTNEKLRKQLERqgcetdqgstnVSAYSSELhNSLTSEIQFLRKQNEALSTML---EKGSK 1411
Cdd:PRK03918 202 LEEVLREINEISSELPELREELEKLEKEVKE-----------LEELKEEI-EELEKELESLEGSKRKLEEKIrelEERIE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1412 EKQKENEKLRESLARkTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVcSSLQELSRVQEEAKSRQQLLLQKD 1491
Cdd:PRK03918 270 ELKKEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEI-NGIEERIKELEEKEERLEELKKKL 347
|
170 180
....*....|....*....|....*....
gi 1958774896 1492 ELLQSLQMELKVYEKLAEEHQKLQQESRG 1520
Cdd:PRK03918 348 KELEKRLEELEERHELYEEAKAKKEELER 376
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1400-1521 |
2.29e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.92 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1400 EALSTMLEKGSKEKQKENEKLRES----LARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVcsslqelsr 1475
Cdd:COG2433 380 EALEELIEKELPEEEPEAEREKEHeereLTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLEREL--------- 450
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1958774896 1476 vqEEAKSRQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQESRGE 1521
Cdd:COG2433 451 --SEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRK 494
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
126-390 |
2.37e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 126 KASKAVESLAEgggSEIQRVKEDARKKVQQVEELLTKRIHLLEEDVKAAQAELEkAFAgtETEKALRLSLESKLSAMKkm 205
Cdd:COG3206 149 LAAAVANALAE---AYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALE-EFR--QKNGLVDLSEEAKLLLQQ-- 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 206 qegdlemtlaLEEKDRLIEELKLSLKSKEALIQCLKEE-KSQMASPDENVSSGELRGLSATLRE-EKERDAEERQKERNH 283
Cdd:COG3206 221 ----------LSELESQLAEARAELAEAEARLAALRAQlGSGPDALPELLQSPVIQQLRAQLAElEAELAELSARYTPNH 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 284 feERIQALQEDLREKEREIATEKKNSLKRDKAiqgltmalkskEKEESENCEAALAEKEALLAKLHSENVTKNTENHRLL 363
Cdd:COG3206 291 --PDVIALRAQIAALRAQLQQEAQRILASLEA-----------ELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
|
250 260
....*....|....*....|....*....
gi 1958774896 364 RNVKKVTQELNDL--KKEKLRLERDLEEA 390
Cdd:COG3206 358 REVEVARELYESLlqRLEEARLAEALTVG 386
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1395-1580 |
2.55e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1395 LRKQNEALSTMLEKGSKEKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEV--CSSLQE 1472
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELekLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1473 LSRVQEEAKSRQQLLLQKDELLQSLQMELKVY-------EKLAEEHQKLQQESRGEACGGGQKGQDPFSNLHGLLKEIQV 1545
Cdd:COG4717 127 LLPLYQELEALEAELAELPERLEELEERLEELreleeelEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206
|
170 180 190
....*....|....*....|....*....|....*
gi 1958774896 1546 LRDQAERSIQTNNTLKSKLEKQLSQGSKQAQEGAL 1580
Cdd:COG4717 207 RLAELEEELEEAQEELEELEEELEQLENELEAAAL 241
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1272-1595 |
2.60e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.90 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1272 RRLRTEEDNLPYQHLLPESpEPSASHALSDDEMSEKSFLSrepKPDSETEKYPTIASRFPQDLlmehIQEIRTLRKHLEE 1351
Cdd:pfam12128 330 QHGAFLDADIETAAADQEQ-LPSWQSELENLEERLKALTG---KHQDVTAKYNRRRSKIKEQN----NRDIAGIKDKLAK 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1352 SIKTNEKLR-------KQLERQ-GCETDQGSTNVSAYSSELHNSLtSEIQFLrkQNEALSTMLEKGSKE-KQKENEKLRE 1422
Cdd:pfam12128 402 IREARDRQLavaeddlQALESElREQLEAGKLEFNEEEYRLKSRL-GELKLR--LNQATATPELLLQLEnFDERIERARE 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1423 SLARKTESLEHLQLEYASVReeneRLRRDISEKERQNQQLTQEVCSSLQELsrvqeeaksRQQLLLQKDELLQSLQMELK 1502
Cdd:pfam12128 479 EQEAANAEVERLQSELRQAR----KRRDQASEALRQASRRLEERQSALDEL---------ELQLFPQAGTLLHFLRKEAP 545
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1503 VYE----KLAEEHQKLQQESRGEACGGGQKGQDPFSNLHGLLKEIQV------------LRDQAERSIQTNNTLKSKLEK 1566
Cdd:pfam12128 546 DWEqsigKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaaseeelreRLDKAEEALQSAREKQAAAEE 625
|
330 340 350
....*....|....*....|....*....|.
gi 1958774896 1567 QLSQGSKQ--AQEGALTLAVQALSVTEWSLQ 1595
Cdd:pfam12128 626 QLVQANGEleKASREETFARTALKNARLDLR 656
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
105-424 |
2.89e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 105 ELKVEVESLKRELQERDQLLVKASKAVESLAEGG-----------------GSEIQRVKEDARKKVQQVEELlTKRIHLL 167
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREDAddleeraeelreeaaelESELEEAREAVEDRREEIEEL-EEEIEEL 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 168 EEDVKAAQAELEKAF-----------AGTETEKALRLSLESKLSAMKKMQE--------------GDLEMTLALEEKDRL 222
Cdd:PRK02224 397 RERFGDAPVDLGNAEdfleelreerdELREREAELEATLRTARERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRER 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 223 IEELKLSLKSKEALIQCLKEE----KSQMASPDENVSSGELRGLSATLREEKERDAEERQKERNHFEERIQALQEDLREK 298
Cdd:PRK02224 477 VEELEAELEDLEEEVEEVEERleraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 299 eREIATEKKnslkrdKAIQGLTMALKSKEKEESENCEA--ALAEKEALLAKLhsENVTKNTENhrlLRNVKKVTQELNDL 376
Cdd:PRK02224 557 -REAAAEAE------EEAEEAREEVAELNSKLAELKERieSLERIRTLLAAI--ADAEDEIER---LREKREALAELNDE 624
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1958774896 377 KKEKLRLERD----LEEAHREgnrgartihdlrNEVEKLRKEVCEREKAVEK 424
Cdd:PRK02224 625 RRERLAEKRErkreLEAEFDE------------ARIEEAREDKERAEEYLEQ 664
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
113-579 |
3.21e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.45 E-value: 3.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 113 LKRELQERDQLLVKASKAVESLAEGGGSEIQRVKEDARKKVQQVEELlTKRIHLLEEDVKAAQAELEKAfagtETEKALR 192
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAEL-QEELEELEEELEELEAELEEL----REELEKL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 193 LSLESKLSAMKKMQEGDLEMTL------ALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATL 266
Cdd:COG4717 122 EKLLQLLPLYQELEALEAELAElperleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 267 rEEKERDAEERQKERNHFEERIQALQEDLREKEREIATEKKN----SLKRDKAIQGLTMALKSKEKEESENCE------- 335
Cdd:COG4717 202 -EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkEARLLLLIAAALLALLGLGGSLLSLILtiagvlf 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 336 --AALAEKEALLAKLHSENVTKNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAH-REGNRGARTIHDLRNEVEKLR 412
Cdd:COG4717 281 lvLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 413 KEVceREKAVEKHYKSLPGESssKFHSQEQVVKGLTESASQEDLllqksnEKDLEAIQQNCYLMtAEELKFGSDGLITEK 492
Cdd:COG4717 361 EEL--QLEELEQEIAALLAEA--GVEDEEELRAALEQAEEYQEL------KEELEELEEQLEEL-LGELEELLEALDEEE 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 493 CSQQspdsklIFSKEKQQSEYEGLTGDLKTEQNVYAHLAKNLQDTD--SKLQAELKRVLALRKQLEQDVLAYRNLQTALQ 570
Cdd:COG4717 430 LEEE------LEELEEELEELEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLE 503
|
....*....
gi 1958774896 571 EQLSEIRKR 579
Cdd:COG4717 504 EAREEYREE 512
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
148-396 |
3.76e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 3.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 148 DARKKVqqveELLTKRIHLLEEDVKAAQAELEKAfagteteKALRLSLESKLSAMKKMQEgdlemtLALEEKDrlieelk 227
Cdd:COG4913 607 DNRAKL----AALEAELAELEEELAEAEERLEAL-------EAELDALQERREALQRLAE------YSWDEID------- 662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 228 lsLKSKEALIQCLKEEKSQMASpdenvSSGELRGLsatlreekerdaeerqkernhfEERIQALQEDLREKEREIATEKK 307
Cdd:COG4913 663 --VASAEREIAELEAELERLDA-----SSDDLAAL----------------------EEQLEELEAELEELEEELDELKG 713
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 308 NSLKRDKAIQGLTMALKSKEKEESENCEAALAEKEALLAKLHSENVTKNTENhRLLRNvkkVTQELNDLKKEKLRLERDL 387
Cdd:COG4913 714 EIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER-ELREN---LEERIDALRARLNRAEEEL 789
|
....*....
gi 1958774896 388 EEAHREGNR 396
Cdd:COG4913 790 ERAMRAFNR 798
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1340-1540 |
4.07e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1340 QEIRTLRKHLEESIKTNEKLRKQLERQGCETDQGSTNVSAYSSELhNSLTSEIQFLRKQNEALSTMLEKGSKE------- 1412
Cdd:COG4942 34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-AALEAELAELEKEIAELRAELEAQKEElaellra 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1413 --KQKENEKLR-----ESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVcSSLQELSRVQEEAK---- 1481
Cdd:COG4942 113 lyRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEERaale 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958774896 1482 ----SRQQLLLQKDELLQSLQMELKVYEKLAEEHQKL-QQESRGEACGGGQKGQDPFSNLHGLL 1540
Cdd:COG4942 192 alkaERQKLLARLEKELAELAAELAELQQEAEELEALiARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1339-1582 |
4.45e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.87 E-value: 4.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1339 IQEIRTLRKHLEESIKTNEKLRKQLERQGC-ETDQGSTNVSAYSSELHNSLTSEIQFLRKQNEALSTMLEKgsKEKQKEN 1417
Cdd:COG5185 288 IKQFENTKEKIAEYTKSIDIKKATESLEEQlAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEA--IKEEIEN 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1418 EKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQN-QQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDELLQS 1496
Cdd:COG5185 366 IVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEIlATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNE 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1497 LQMEL-KVYEKLAEEHQKLQQESRGEACGGGQkgqdpfSNLHGLLKEIQVLRDQAERSIQTNNTLKSKLEKQLSQGSKQA 1575
Cdd:COG5185 446 LISELnKVMREADEESQSRLEEAYDEINRSVR------SKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKL 519
|
....*..
gi 1958774896 1576 QEGALTL 1582
Cdd:COG5185 520 DQVAESL 526
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
230-401 |
4.84e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.62 E-value: 4.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 230 LKSKEAliQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEERQKERNHFEERIQALQEDLREKEREIATEKKNS 309
Cdd:PRK12705 30 RLAKEA--ERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 310 LKRDKAIQGLTMALkskeKEESENCEAALAEKEALlaklhsenvTKNTENHRLLRNVKKvtqelnDLKKEK-LRLERDLE 388
Cdd:PRK12705 108 EEREKALSARELEL----EELEKQLDNELYRVAGL---------TPEQARKLLLKLLDA------ELEEEKaQRVKKIEE 168
|
170
....*....|...
gi 1958774896 389 EAHREGNRGARTI 401
Cdd:PRK12705 169 EADLEAERKAQNI 181
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1386-1577 |
5.11e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1386 NSLTSEIQFLRKQNEALSTMLEkgskEKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQNQQLTQE 1465
Cdd:COG4372 48 EQLREELEQAREELEQLEEELE----QARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1466 VCSSLQELSRVQEEAKSRQQLLLQKDELLQSLQMELkvyEKLAEEHQKLQQESRGEacgggqkgqdpfsNLHGLLKEIQV 1545
Cdd:COG4372 124 RQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQL---ESLQEELAALEQELQAL-------------SEAEAEQALDE 187
|
170 180 190
....*....|....*....|....*....|..
gi 1958774896 1546 LRDQAERSIQTNNTLKSKLEKQLSQGSKQAQE 1577
Cdd:COG4372 188 LLKEANRNAEKEEELAEAEKLIESLPRELAEE 219
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
96-631 |
5.88e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.49 E-value: 5.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 96 TEHIYKKNIELKVEVESLKRELQERDQLLVKASKAVESLAEGGGSEIQRVKEDARKKVQQvEELLTKRIHLLEE--DVKA 173
Cdd:TIGR00618 378 TQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQ-RYAELCAAAITCTaqCEKL 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 174 AQAELEKAFAGTETEKALRLSLESKLSAMKKMQEGDLEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDEN 253
Cdd:TIGR00618 457 EKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQT 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 254 VSSGE-----LRGLSATLREEKERDAEERQKERNHFE---ERIQALQED---LREKEREIATEKKNSLKRDKAIQGLTMA 322
Cdd:TIGR00618 537 YAQLEtseedVYHQLTSERKQRASLKEQMQEIQQSFSiltQCDNRSKEDipnLQNITVRLQDLTEKLSEAEDMLACEQHA 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 323 LKSKEKEESENCEAAL-----AEKEAL-LAKLHSENVT----KNTENHRLLRNVKKVTQELNDLKKEKLRLERDLEEAHR 392
Cdd:TIGR00618 617 LLRKLQPEQDLQDVRLhlqqcSQELALkLTALHALQLTltqeRVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWK 696
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 393 EG-NRGARTIHDLRNEVEKLRKEVCEREKAVEKHYKSLPGESSSKFHSQEQVVKGLTESASQEDLLLQKSNEKDLEAIQQ 471
Cdd:TIGR00618 697 EMlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQT 776
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 472 NCYLMTAEelkfgsdGLITEKCSQQSPDSKLIFSKEKQQSEYEGLTGDLKTEQNVyaHLAKNLQDTDSKLQAELKRVLAL 551
Cdd:TIGR00618 777 GAELSHLA-------AEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCE--TLVQEEEQFLSRLEEKSATLGEI 847
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 552 RKQLEQDVLAYRNLQTALQEQLS--------------EIRKREEEPFSFYSDQTSYLSICL--EEHSQFQLEHFSQEEIK 615
Cdd:TIGR00618 848 THQLLKYEECSKQLAQLTQEQAKiiqlsdklnginqiKIQFDGDALIKFLHEITLYANVRLanQSEGRFHGRYADSHVNA 927
|
570
....*....|....*.
gi 1958774896 616 KKVIDLIQLVKDLHAD 631
Cdd:TIGR00618 928 RKYQGLALLVADAYTG 943
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
60-332 |
5.89e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.48 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 60 MKDFENQITELKKENFNLKLRIYFLEERIQQEFAGPTEHIYKKNIELKVEVESLKRELQER-DQLLVKASKAVESLAEG- 137
Cdd:COG5185 277 SKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGiQNLTAEIEQGQESLTENl 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 138 -----------GGSEIQRVKEDARKKVQQVE----ELLTKRIHLLEEDVKAAQAELEKAFAGTETEKALRLSLESKLSAM 202
Cdd:COG5185 357 eaikeeienivGEVELSKSSEELDSFKDTIEstkeSLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSN 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 203 KKMQEGDLEMTLALEEKDRLIEELKLSlKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREEKERDAEERQKERN 282
Cdd:COG5185 437 EEVSKLLNELISELNKVMREADEESQS-RLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGV 515
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1958774896 283 HFEERIQALQEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKEESE 332
Cdd:COG5185 516 RSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANL 565
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
230-470 |
6.32e-03 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 40.90 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 230 LKSKEALIQCLKEEKSQMASPDENVSSGELrglsatlreekerdaEERQKERNHFEERIQALQEDLREKEREIATekkns 309
Cdd:pfam09787 20 LQSKEKLIASLKEGSGVEGLDSSTALTLEL---------------EELRQERDLLREEIQKLRGQIQQLRTELQE----- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 310 lkrdkaiqgltmaLKSKEKEESENCEAALAEKEallaklhsENVTKNTENHRLlrnvkkVTQELNDLKKEKLRLERDLee 389
Cdd:pfam09787 80 -------------LEAQQQEEAESSREQLQELE--------EQLATERSARRE------AEAELERLQEELRYLEEEL-- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 390 aHREGNRGARTIHDLRNEVEKLRKEVCErekavekhyKSLPGESSSKFhsqEQVVKGLTESASQEDLLLQK-SNEKDLEA 468
Cdd:pfam09787 131 -RRSKATLQSRIKDREAEIEKLRNQLTS---------KSQSSSSQSEL---ENRLHQLTETLIQKQTMLEAlSTEKNSLV 197
|
..
gi 1958774896 469 IQ 470
Cdd:pfam09787 198 LQ 199
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
266-422 |
6.73e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 6.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 266 LREEKERDAEERQKERNHFEERIQALQEDLREKEREIAT--EKKNSLKRDKAIQGLTMALKSKEKEESENcEAALAEKEA 343
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEA-RAELAEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 344 LLAKLHSENVTKNTENHRLLRN--VKKVTQELNDLKKEKLRLERDLEEAHREgnrgartIHDLRNEVEKLRKEVCEREKA 421
Cdd:COG3206 241 RLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPD-------VIALRAQIAALRAQLQQEAQR 313
|
.
gi 1958774896 422 V 422
Cdd:COG3206 314 I 314
|
|
| Rab5-bind |
pfam09311 |
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow ... |
1337-1516 |
7.35e-03 |
|
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.
Pssm-ID: 462752 [Multi-domain] Cd Length: 307 Bit Score: 40.72 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1337 EHIQEIRTLRKHLEESIKtneklrkqlerqgcetdqgstnvsaysselhnsltSEIQFLRKQNEALSTMLEKGSKEKQKE 1416
Cdd:pfam09311 154 EELIEVRTAADHMEEKLK-----------------------------------AEILFLKEQIQAEQCLKENLEETLQAE 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1417 NEKLRESLArkteSLEHLQLEYASVREENERLRRDISEKERQNQQLTQEVCSSLQELSRVQEEAKSRQQLLLQKDELLQS 1496
Cdd:pfam09311 199 IENCKEEIA----SISSLKVELERIKAEKEQLENGLTEKIRQLEDLQTTKGSLETQLKKETNEKAAVEQLVFEEKNKAQR 274
|
170 180
....*....|....*....|
gi 1958774896 1497 LQMELKVYEKLAEEHQKLQQ 1516
Cdd:pfam09311 275 LQTELDVSEQVQRDFVKLSQ 294
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
258-372 |
8.16e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.22 E-value: 8.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 258 ELRGLSATLRE-EKERDAEERQKERNHFEeRIQALQEDLREKEREIATEKKNSLKRDKAIQGLTmalksKEKEESENCEA 336
Cdd:COG0542 412 ELDELERRLEQlEIEKEALKKEQDEASFE-RLAELRDELAELEEELEALKARWEAEKELIEEIQ-----ELKEELEQRYG 485
|
90 100 110
....*....|....*....|....*....|....*.
gi 1958774896 337 ALAEKEALLAKLHSEnvtkNTENHRLLRNVkkVTQE 372
Cdd:COG0542 486 KIPELEKELAELEEE----LAELAPLLREE--VTEE 515
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1297-1522 |
9.21e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.11 E-value: 9.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1297 HALSDDEMSEKSFLSREPKPDSETEKYPTIASrfpqdlLMEHIQEIRTLRKHLEESIKTNEKLRKQLERqgCETDQGSTn 1376
Cdd:TIGR00618 663 HALSIRVLPKELLASRQLALQKMQSEKEQLTY------WKEMLAQCQTLLRELETHIEEYDREFNEIEN--ASSSLGSD- 733
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1377 vSAYSSELHNSLTSEIQFLRKqnealsTMLEKGSKEKQKENEKLRESLARKTEsLEHLQLEYASVREENERLRRDISEKE 1456
Cdd:TIGR00618 734 -LAAREDALNQSLKELMHQAR------TVLKARTEAHFNNNEEVTAALQTGAE-LSHLAAEIQFFNRLREEDTHLLKTLE 805
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958774896 1457 RQNQQltqEVCSSLQELSRVQEEAKSRQQLLLQKDELLQSLQMELK-VYEKLAEEHQKLQQESRGEA 1522
Cdd:TIGR00618 806 AEIGQ---EIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEIThQLLKYEECSKQLAQLTQEQA 869
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1409-1598 |
9.99e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.82 E-value: 9.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1409 GSKEKQKENEKLRESLARKTESLEHLQLEYASVREENERLRRDISEKERQnqqltQEVCSSLQE------LSRVQEEAKS 1482
Cdd:TIGR02169 164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERY-----QALLKEKREyegyelLKEKEALERQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958774896 1483 RQQLLLQKDELLQSLQMELKVYEKLAEEHQKLQQESRGEACGGGQKGQDPFSNLHGLLKEIQVLRDQAERSIQTNNTLKS 1562
Cdd:TIGR02169 239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318
|
170 180 190
....*....|....*....|....*....|....*.
gi 1958774896 1563 KLEKQLSQGSKQAQEGALTLAVQALSVTEWSLQLDK 1598
Cdd:TIGR02169 319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354
|
|
| |
