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Conserved domains on  [gi|1958769184|ref|XP_038963400|]
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dynein axonemal intermediate chain 7 isoform X6 [Rattus norvegicus]

Protein Classification

DUF814 domain-containing protein( domain architecture ID 12175428)

DUF814 domain-containing protein similar to vertebrates coiled-coil domain-containing protein 25, yeast protein JLP2, and bacterial fibronectin/fibrinogen-binding protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Casc1_N pfam15927
Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally ...
 1-136 2.14e-47

Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is approximately 200 amino acids in length. The family is found in association with pfam12366. There are two completely conserved residues (N and W) that may be functionally important.


:

Pssm-ID: 464947 [Multi-domain]  Cd Length: 201  Bit Score: 165.23  E-value: 2.14e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769184   1 MRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEEKNETFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKSTVLQYQGS 80
Cdd:pfam15927  66 AREEAEWERYMRCDGLPDPRDEQEINTFISLWREEEEEDIDEVMETCTLVLELIEELEELLLDTPPEELAEKYVEQYKEV 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958769184  81 ILRLQELLSLKVNVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPR 136
Cdd:pfam15927 146 ILVLRELINKKIDEATAHLLRQADEYADRETGNMQKVVKDGNITLCLWANLKKNPR 201
 
Name Accession Description Interval E-value
Casc1_N pfam15927
Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally ...
 1-136 2.14e-47

Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is approximately 200 amino acids in length. The family is found in association with pfam12366. There are two completely conserved residues (N and W) that may be functionally important.


Pssm-ID: 464947 [Multi-domain]  Cd Length: 201  Bit Score: 165.23  E-value: 2.14e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769184   1 MRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEEKNETFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKSTVLQYQGS 80
Cdd:pfam15927  66 AREEAEWERYMRCDGLPDPRDEQEINTFISLWREEEEEDIDEVMETCTLVLELIEELEELLLDTPPEELAEKYVEQYKEV 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958769184  81 ILRLQELLSLKVNVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPR 136
Cdd:pfam15927 146 ILVLRELINKKIDEATAHLLRQADEYADRETGNMQKVVKDGNITLCLWANLKKNPR 201
 
Name Accession Description Interval E-value
Casc1_N pfam15927
Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally ...
 1-136 2.14e-47

Cancer susceptibility candidate 1 N-terminus; This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is approximately 200 amino acids in length. The family is found in association with pfam12366. There are two completely conserved residues (N and W) that may be functionally important.


Pssm-ID: 464947 [Multi-domain]  Cd Length: 201  Bit Score: 165.23  E-value: 2.14e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958769184   1 MRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEEKNETFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKSTVLQYQGS 80
Cdd:pfam15927  66 AREEAEWERYMRCDGLPDPRDEQEINTFISLWREEEEEDIDEVMETCTLVLELIEELEELLLDTPPEELAEKYVEQYKEV 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958769184  81 ILRLQELLSLKVNVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPR 136
Cdd:pfam15927 146 ILVLRELINKKIDEATAHLLRQADEYADRETGNMQKVVKDGNITLCLWANLKKNPR 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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