cyclin-D-binding Myb-like transcription factor 1 isoform X3 [Rattus norvegicus]
cyclin-D-binding Myb-like transcription factor 1( domain architecture ID 13419776)
cyclin-D-binding Myb-like transcription factor 1 (DMTF1) is a transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest
List of domain hits
Name | Accession | Description | Interval | E-value | ||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 3.56e-23 | ||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. : Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 3.56e-23
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 2.05e-10 | ||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. : Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 55.59 E-value: 2.05e-10
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.69e-09 | ||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. : Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 52.31 E-value: 4.69e-09
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
336-389 | 2.84e-03 | ||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; : Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 35.66 E-value: 2.84e-03
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Name | Accession | Description | Interval | E-value | |||||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 3.56e-23 | |||||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 3.56e-23
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 2.05e-10 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 55.59 E-value: 2.05e-10
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.69e-09 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 52.31 E-value: 4.69e-09
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
275-329 | 1.11e-08 | |||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 50.65 E-value: 1.11e-08
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
274-330 | 1.67e-08 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 50.30 E-value: 1.67e-08
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
122-378 | 8.19e-08 | |||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.41 E-value: 8.19e-08
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
225-270 | 8.72e-06 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 42.60 E-value: 8.72e-06
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
226-268 | 9.91e-06 | |||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 42.18 E-value: 9.91e-06
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
336-389 | 2.84e-03 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 35.66 E-value: 2.84e-03
|
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Name | Accession | Description | Interval | E-value | |||||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 3.56e-23 | |||||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 3.56e-23
|
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 2.05e-10 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 55.59 E-value: 2.05e-10
|
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.69e-09 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 52.31 E-value: 4.69e-09
|
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
275-329 | 1.11e-08 | |||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 50.65 E-value: 1.11e-08
|
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
274-330 | 1.67e-08 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 50.30 E-value: 1.67e-08
|
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
122-378 | 8.19e-08 | |||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.41 E-value: 8.19e-08
|
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
225-268 | 1.32e-07 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 47.50 E-value: 1.32e-07
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
276-347 | 2.34e-06 | |||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 44.61 E-value: 2.34e-06
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
225-270 | 8.72e-06 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 42.60 E-value: 8.72e-06
|
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
226-268 | 9.91e-06 | |||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 42.18 E-value: 9.91e-06
|
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
336-389 | 2.84e-03 | |||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 35.66 E-value: 2.84e-03
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Blast search parameters | ||||
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