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Conserved domains on  [gi|1958767521|ref|XP_038962800|]
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centrosome-associated protein CEP250 isoform X3 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 559-1112 1.47e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 1.47e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  559 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 638
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 718
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 798
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 878
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  879 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 958
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  959 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 1038
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521 1039 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 1112
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 226-829 1.05e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  226 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLE 305
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  306 SELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKN 385
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  386 EEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsrev 465
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE------------- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  466 dlqqeqiqeleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRgqiqDLKKQL 545
Cdd:COG1196    446 ----------------------EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL----LLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  546 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQ-LHELENHSTRLAKELQERDQE 624
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  625 VMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 704
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  705 DGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLqglhRKVGETSLLLTHREQETATLQQRLQEAK 784
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----RELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958767521  785 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESM 829
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 8-354 4.50e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    8 EDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqkelekekasltlSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEA 87
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASR--------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   88 QEGQRELGVQVELLRQEVKEKEADFVAREAQlLEELEASRIAER--QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEA-LNDLEARLSHSRipEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVptpwgsdpdqngASRLLKRGPLLTALSAEAVALALQ--KLHQ 243
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL------------EEELEELEAALRDLESRLGDLKKErdELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  244 DLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkSKWEGKQNSLESELRDLHETMASLQSRLR 323
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRALEPVNM 975

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1958767521  324 QAELQKMEAQNDRELLQASKEKLSAQVEHLQ 354
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 950-1298 7.56e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  950 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1029
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1030 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 1108
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1109 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 1185
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1186 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 1265
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767521 1266 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 1298
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 559-1112 1.47e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 1.47e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  559 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 638
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 718
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 798
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 878
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  879 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 958
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  959 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 1038
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521 1039 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 1112
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 257-1060 2.47e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 2.47e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  257 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 336
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  337 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 412
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  413 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 492
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  493 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 559
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  560 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 639
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  640 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 719
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  720 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 796
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  797 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 876
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  877 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 956
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  957 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 1035
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767521 1036 ELCQKEEDLrqqDEQRQLLEKAVAQ 1060
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 226-829 1.05e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  226 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLE 305
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  306 SELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKN 385
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  386 EEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsrev 465
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE------------- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  466 dlqqeqiqeleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRgqiqDLKKQL 545
Cdd:COG1196    446 ----------------------EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL----LLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  546 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQ-LHELENHSTRLAKELQERDQE 624
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  625 VMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 704
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  705 DGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLqglhRKVGETSLLLTHREQETATLQQRLQEAK 784
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----RELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958767521  785 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESM 829
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 28-868 2.36e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 2.36e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   28 IEEKVREAQECSRIQKEL-EKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQVELLRQEVK 106
Cdd:TIGR02168  205 LERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  107 EKEADFVAREAQLLEELEASRIAERQVRaslwAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 186
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQ----ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  187 gsacerrpelrgggdsvptpwgsdpdqngasrllkrgplltalsaEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 266
Cdd:TIGR02168  354 ---------------------------------------------ESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  267 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHetMASLQSRLRQAELQKMEAQNDRELLQASKEKL 346
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  347 SAQVEHLQACVTEARAQASAAG----VLEEDLRTARSALKLKNEEIESERERAQALQEQGEL-------KVAQGKALQEN 415
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQarldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  416 LTLLAqtlsnrereVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQK 495
Cdd:TIGR02168  547 LQAVV---------VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  496 LSVQRDQIRELENDREAQRTALEHQLLDL-------------------EQKAQVIESQRGQIQDLKKQLgtleclalelE 556
Cdd:TIGR02168  618 LSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKI----------E 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  557 ESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQ 636
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  637 KQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEdLEQIKHSLRERGQELASQWQLMQERAEdgkspskaqrgs 716
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAELTLLNEEAANLRERLESLERRIA------------ 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  717 lehlklilrDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ- 795
Cdd:TIGR02168  835 ---------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRe 905

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  796 --GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKE-RQGELEEHRGQVQRLQEEL 868
Cdd:TIGR02168  906 leSKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkIEDDEEEARRRLKRLENKI 981
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
256-821 9.47e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 73.15  E-value: 9.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  256 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 335
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  336 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 415
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  416 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 495
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  496 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 575
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  576 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 655
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  656 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 735
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  736 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 815
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767521  816 RQEQQQ 821
Cdd:PRK02224   714 YDEAEE 719
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
373-891 5.01e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.84  E-value: 5.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  373 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 445
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  446 MQKAALE--LLSLDLKKRSREV--DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 521
Cdd:PRK02224   290 ELEEERDdlLAEAGLDDADAEAveARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  522 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 601
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  602 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 667
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  668 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 741
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  742 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 820
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767521  821 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 891
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 247-951 2.57e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  247 KAQQARDDLRDQVQKLVQRLtdtEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDL----------HETMA 316
Cdd:pfam15921  135 RESQSQEDLRNQLQNTVHEL---EAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFeeasgkkiyeHDSMS 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  317 SLQSRLRQAELQKMEAQNDREL--LQASKEKLSAQVEHLQacvteARAQASAAGVLEEDLRTARSALKLKNEEI-----E 389
Cdd:pfam15921  212 TMHFRSLGSAISKILRELDTEIsyLKGRIFPVEDQLEALK-----SESQNKIELLLQQHQDRIEQLISEHEVEItglteK 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  390 SERERAQALQEQGELKVAQGKALQENLTLLAQtLSNREREVETLQAEVQELEKQREMQKAALE-LLSLDLKKRSREVDLQ 468
Cdd:pfam15921  287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQ-LSDLESTVSQLRSELREAKRMYEDKIEELEkQLVLANSELTEARTER 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  469 QEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL-GT 547
Cdd:pfam15921  366 DQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  548 LECLALELEESHRKVEGQQKVITELEGQRELQRVALthltldleersQELQTQSSQLHELENHSTRLAKELQERDQEVMS 627
Cdd:pfam15921  446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVV-----------EELTAKKMTLESSERTVSDLTASLQEKERAIEA 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  628 QRQQIEELQKQ---KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 704
Cdd:pfam15921  515 TNAEITKLRSRvdlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQ 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  705 DGKSPSKaQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAK 784
Cdd:pfam15921  595 LEKEIND-RRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  785 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRL 864
Cdd:pfam15921  674 EDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFL 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  865 QEELIVEGRQVRALEEVLGDLRAESreheKTVLALQQRCAEQAQEHEAEARTLQDSwlQAQATLAEQEQELEALRAENQY 944
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQEL----STVATEKNKMAGELEVLRSQERRLKEK--VANMEVALDKASLQFAECQDII 827


                   ....*..
gi 1958767521  945 SRQQEEA 951
Cdd:pfam15921  828 QRQEQES 834
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 84-951 9.04e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 9.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   84 IQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVA 163
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  164 EQQPENQAQAQLRSLYSVLQQALGSACERRPELrgggdsvptpwGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQ 243
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLL-----------AKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  244 DLWKAQQARDDLRDQVQKLVQRltDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLR 323
Cdd:pfam02463  328 KELKKEKEEIEELEKELKELEI--KREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  324 QAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGE 403
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  404 LKVAQGKALQEnltllaqtlsnrerEVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLE 483
Cdd:pfam02463  486 LELLLSRQKLE--------------ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  484 HLPMAVQEREQKLSVQRdqiRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHR-KV 562
Cdd:pfam02463  552 EVSATADEVEERQKLVR---ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVeGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  563 EGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQL 642
Cdd:pfam02463  629 LKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  643 TQDLERKGQELVLQKERIQVL------EDQRTLQTKILEEDLEQIKHSL-RERGQELASQWQLMQERAEDGKSPSKaqrg 715
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEaqdkinEELKLLKQKIDEEEEEEEKSRLkKEEKEEEKSELSLKEKELAEEREKTE---- 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  716 sLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ 795
Cdd:pfam02463  785 -KLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  796 GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQV 875
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKK---ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  876 RALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEA 951
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 761-1010 1.86e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 1.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  761 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 840
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  841 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 918
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  919 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 998
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767521  999 DTCQARARQLEE 1010
Cdd:NF012221  1765 AQADAKGAKQDE 1776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 8-354 4.50e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    8 EDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqkelekekasltlSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEA 87
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASR--------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   88 QEGQRELGVQVELLRQEVKEKEADFVAREAQlLEELEASRIAER--QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEA-LNDLEARLSHSRipEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVptpwgsdpdqngASRLLKRGPLLTALSAEAVALALQ--KLHQ 243
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL------------EEELEELEAALRDLESRLGDLKKErdELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  244 DLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkSKWEGKQNSLESELRDLHETMASLQSRLR 323
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRALEPVNM 975

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1958767521  324 QAELQKMEAQNDRELLQASKEKLSAQVEHLQ 354
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
PRK12704 PRK12704
phosphodiesterase; Provisional
 19-174 2.71e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   19 DSQRLVKQEIEEKVREAQ-ECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQ 97
Cdd:PRK12704    46 EAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEK-------E 118

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521   98 VELLRQEVKEKEADFVAREAQLLEELEasRIaerqvrASLWAQEAKAAQLQlQLRStEAQLEALVAEQQPENQAQAQ 174
Cdd:PRK12704   119 LEQKQQELEKKEEELEELIEEQLQELE--RI------SGLTAEEAKEILLE-KVEE-EARHEAAVLIKEIEEEAKEE 185
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
26-161 3.07e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   26 QEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEA----DSVR----QRELVSLRQDIQEAQEGQRELGVQ 97
Cdd:COG4913    288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnGGDRleqlEREIERLERELEERERRRARLEAL 367

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521   98 VELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEAL 161
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 950-1298 7.56e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  950 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1029
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1030 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 1108
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1109 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 1185
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1186 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 1265
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767521 1266 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 1298
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 559-1112 1.47e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.40  E-value: 1.47e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  559 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 638
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 718
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 798
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 878
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  879 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 958
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  959 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 1038
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521 1039 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 1112
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 727-1269 1.73e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 1.73e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  727 KEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAkeqgELREQVLQGQLEEAQRALA 806
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  807 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLR 886
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  887 AESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKA 966
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEA----LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  967 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQkeEDLRQ 1046
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA--VLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1047 QDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE---EILMLREAQQRQNQEASSPSHRS 1123
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAalaAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1124 FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEEL 1203
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1204 VLSRQALEEQQSRGPHSSSRADQG----------------------PKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERL 1261
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERleeeleeealeeqleaereellEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*...
gi 1958767521 1262 QQAVAELE 1269
Cdd:COG1196    773 EREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 735-1313 2.40e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.09  E-value: 2.40e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  735 QERIQELQEHMGQLEQQLQGLHRkvgetslllthrEQETATLQQRLQEAKEQGELREQVL-----QGQLEEAQRALAQRD 809
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER------------QAEKAERYRELKEELKELEAELLLLklrelEAELEELEAELEELE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  810 HELEALRQEQQQTRGQEESMKQKTSALQAALEqahvtlkERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAES 889
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEELELELE-------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  890 REHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQAT 969
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELE----EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  970 LQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEEALRVREGEIQTQALQHQEAMQHLQQELcqkEEDLRQQDE 1049
Cdd:COG1196    402 LEELEEAEEALLE---------------------RLERLEEELEELEEALAELEEEEEEEEEALEEAA---EEEAELEEE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1050 QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 1129
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1130 SLQLLLAQQDLERLQNALRQTEAREIEW-----REKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELV 1204
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVAAAAIEYlkaakAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1205 LSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRT 1284
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          570       580
                   ....*....|....*....|....*....
gi 1958767521 1285 TLEQVERERRKLKRDSLRASRAGSLEARE 1313
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEAL 726
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 257-1060 2.47e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 2.47e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  257 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 336
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  337 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 412
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  413 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 492
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  493 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 559
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  560 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 639
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  640 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 719
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  720 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 796
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  797 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 876
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  877 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 956
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  957 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 1035
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767521 1036 ELCQKEEDLrqqDEQRQLLEKAVAQ 1060
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 247-982 5.89e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 5.89e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  247 KAQQARDDLRD-QVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQA 325
Cdd:TIGR02168  214 RYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  326 -------ELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----R 394
Cdd:TIGR02168  294 aneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  395 AQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQE 474
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  475 LEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL--- 541
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisv 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  542 KKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEeRSQELQTQSSQLHELENHSTRLAKELQER 621
Cdd:TIGR02168  532 DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSI-KGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  622 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELvlQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQE 701
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLDNALELAKKLR--PGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  702 RAEDgkspskaqrgslehlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL- 780
Cdd:TIGR02168  689 LEEK------------------IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIa 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  781 QEAKEQGELREQ--VLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtLKERQGELEEhr 858
Cdd:TIGR02168  751 QLSKELTELEAEieELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAANLRE-- 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  859 gQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEAL 938
Cdd:TIGR02168  825 -RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA----LLNERASLEEALALLRSELEEL 899

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958767521  939 RAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 982
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 226-829 1.05e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  226 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLE 305
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  306 SELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKN 385
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  386 EEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsrev 465
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE------------- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  466 dlqqeqiqeleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRgqiqDLKKQL 545
Cdd:COG1196    446 ----------------------EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL----LLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  546 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQ-LHELENHSTRLAKELQERDQE 624
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  625 VMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 704
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  705 DGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLqglhRKVGETSLLLTHREQETATLQQRLQEAK 784
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----RELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958767521  785 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESM 829
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 500-1060 6.57e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 6.57e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  500 RDQIRELENDREAQRTALEHQ----LLDLEQKAQVIESQRGQIQDLKKQLGTLEclaleleeshRKVEGQQKVITELEGQ 575
Cdd:COG1196    199 ERQLEPLERQAEKAERYRELKeelkELEAELLLLKLRELEAELEELEAELEELE----------AELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  576 RELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVL 655
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  656 QKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEdgkspskaQRGSLEHLKLILRDKEKEVECQQ 735
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--------LAAQLEELEEAEEALLERLERLE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  736 ERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 815
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  816 RQEQQQTRGQEESMKQK--------------------------------------TSALQAALEQAHVTLKERQGELEEH 857
Cdd:COG1196    501 ADYEGFLEGVKAALLLAglrglagavavligveaayeaaleaalaaalqnivvedDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  858 RGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLA-------- 929
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsagg 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  930 EQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSctleastatlqatLDTCQARARQLE 1009
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE-------------RLEEELEEEALE 727

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767521 1010 EALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 1060
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 569-1268 4.83e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 4.83e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  569 ITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKE-------Q 641
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrerlaN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  642 LTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKhSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLK 721
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  722 LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETatlqqrLQEAKEQGELREQVLQGQLEEA 801
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE------LEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  802 QRALAQRDHELEALRQEQQQTRGQEESMKQktsaLQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEV 881
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLER----LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  882 LG------------------DLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEAL----- 938
Cdd:TIGR02168  543 LGgrlqavvvenlnaakkaiAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyll 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  939 ----------RAENQYSRQQEEAAFGQAE--------ALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDT 1000
Cdd:TIGR02168  623 ggvlvvddldNALELAKKLRPGYRIVTLDgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1001 CQARARQLEEALR-VREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEE 1079
Cdd:TIGR02168  703 LRKELEELEEELEqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1080 ETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHR-----------SFPAEKPSLQLLLAQQDLERLQNALR 1148
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERleslerriaatERRLEDLEEQIEELSEDIESLAAEIE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1149 QTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSRGPHSSSRAD--Q 1226
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnlQ 942

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1958767521 1227 GPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAEL 1268
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 237-972 2.86e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 2.86e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  237 ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMA 316
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  317 SLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvleedlrtarsalklkneEIESERERAQ 396
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL-------------------EDRRERLQQE 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  397 ALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE 476
Cdd:TIGR02168  423 IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  477 QCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQviESQRGQIQDLKKQLGTLECLALELE 556
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL--NAAKKAIAFLKQNELGRVTFLPLDS 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  557 ESHRKVEGQQKVIteLEGQRELQRVALTHLTLDLEER------------SQELQTQSSQLHELENHST------------ 612
Cdd:TIGR02168  581 IKGTEIQGNDREI--LKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvVDDLDNALELAKKLRPGYRivtldgdlvrpg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  613 -RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL-VLQKERIQVLEDQRTLQTKILEED-----LEQIKHSL 685
Cdd:TIGR02168  659 gVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALaELRKELEELEEELEQLRKELEELSrqisaLRKDLARL 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  686 RERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLL 765
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  766 LTHREQETATLQQRLQEAKEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHV 845
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  846 TLKERQGELEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSW 921
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRREL-------EELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDE 967

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521  922 LQAQATLAEQEQELEA-----LRAENQYSRQQEEAAF--GQAEALQEALSKAQATLQE 972
Cdd:TIGR02168  968 EEARRRLKRLENKIKElgpvnLAAIEEYEELKERYDFltAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 311-1112 3.48e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 3.48e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  311 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 390
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  391 ERERAQALQEQgelkvaqgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQE 470
Cdd:TIGR02168  275 EVSELEEEIEE----------LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  471 QIQELEQCrsvLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALehqlLDLEQKAQVIESQRGQIQDLKKQLGTLEC 550
Cdd:TIGR02168  345 KLEELKEE---LESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  551 LALELEESHRKvEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMS--- 627
Cdd:TIGR02168  418 RLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSler 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  628 QRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIkhsLRERGQELASQWQLMQERAEDGK 707
Cdd:TIGR02168  497 LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAV---VVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  708 SPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgeTSLLLTHREQETATLQQRLQEAKE-- 785
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYri 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  786 ---QGEL--REQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQ 860
Cdd:TIGR02168  648 vtlDGDLvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  861 VQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEA 937
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  938 LRAEnqYSRQQEEAAfgqaeALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREG 1017
Cdd:TIGR02168  808 LRAE--LTLLNEEAA-----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1018 EIQtqalQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENG--IQEKQSLEQEKEEETRGLLESLKELQLTV 1095
Cdd:TIGR02168  881 ERA----SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAqlELRLEGLEVRIDNLQERLSEEYSLTLEEA 956

                          810
                   ....*....|....*..
gi 1958767521 1096 AQKEEEILMLREAQQRQ 1112
Cdd:TIGR02168  957 EALENKIEDDEEEARRR 973
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 304-868 8.19e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 8.19e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  304 LESELRDLHETMASLQSRLRQAELQKMEAQndRELLQASKEKLSAQVEHLQACVTEARAQASAAG----VLEEDLRTARS 379
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELEELEleleEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  380 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLK 459
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  460 KRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQ 539
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  540 DLKKQLGTLECLALELEESHRKVEGQQkvitelegQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ 619
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAEL--------LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  620 ERDQEVMSQRQQIEE-----LQKQKEQLTQDLERKGQELVLQKE-RIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELA 693
Cdd:COG1196    528 VLIGVEAAYEAALEAalaaaLQNIVVEDDEVAAAAIEYLKAAKAgRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  694 SQWQLMQERAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLthREQET 773
Cdd:COG1196    608 LREADARYYVLG----DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE--AEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  774 ATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGE 853
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*
gi 1958767521  854 LEEHRGQVQRLQEEL 868
Cdd:COG1196    762 LEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 28-868 2.36e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 2.36e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   28 IEEKVREAQECSRIQKEL-EKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQVELLRQEVK 106
Cdd:TIGR02168  205 LERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  107 EKEADFVAREAQLLEELEASRIAERQVRaslwAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 186
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQ----ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  187 gsacerrpelrgggdsvptpwgsdpdqngasrllkrgplltalsaEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 266
Cdd:TIGR02168  354 ---------------------------------------------ESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  267 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHetMASLQSRLRQAELQKMEAQNDRELLQASKEKL 346
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  347 SAQVEHLQACVTEARAQASAAG----VLEEDLRTARSALKLKNEEIESERERAQALQEQGEL-------KVAQGKALQEN 415
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQarldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  416 LTLLAqtlsnrereVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQK 495
Cdd:TIGR02168  547 LQAVV---------VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  496 LSVQRDQIRELENDREAQRTALEHQLLDL-------------------EQKAQVIESQRGQIQDLKKQLgtleclalelE 556
Cdd:TIGR02168  618 LSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKI----------E 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  557 ESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQ 636
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  637 KQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEdLEQIKHSLRERGQELASQWQLMQERAEdgkspskaqrgs 716
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAELTLLNEEAANLRERLESLERRIA------------ 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  717 lehlklilrDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ- 795
Cdd:TIGR02168  835 ---------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRe 905

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  796 --GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKE-RQGELEEHRGQVQRLQEEL 868
Cdd:TIGR02168  906 leSKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 29-688 1.11e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   29 EEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEK 108
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  109 EADfVAREAQLLEELEASRIAERQVRASLwaqEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALgs 188
Cdd:COG1196    301 EQD-IARLEERRRELEERLEELEEELAEL---EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL-- 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  189 acerrpelrgggdsvptpwgsdpdqngasrllkrgplltalsaEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTD 268
Cdd:COG1196    375 -------------------------------------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  269 TEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSA 348
Cdd:COG1196    412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  349 QVEHLQAcvTEARAQASAAGVLEEDLRTARSALklkneeiesererAQALQEQGELKVAQGKALQenlTLLAQTLSNRER 428
Cdd:COG1196    492 RLLLLLE--AEADYEGFLEGVKAALLLAGLRGL-------------AGAVAVLIGVEAAYEAALE---AALAAALQNIVV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  429 EVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELEN 508
Cdd:COG1196    554 EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  509 DREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGT--LECLALELEESHRKVEGQQKVITELEGQRELQRVALTHL 586
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAalLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  587 TLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQ---QIEELQKQKEQLTQDLERKG-------QELVLQ 656
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPeppDLEELERELERLEREIEALGpvnllaiEEYEEL 793

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1958767521  657 KERIQVLEDQRtlqtkileEDLEQIKHSLRER 688
Cdd:COG1196    794 EERYDFLSEQR--------EDLEEARETLEEA 817
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 21-653 1.23e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   21 QRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVEL 100
Cdd:COG1196    241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  101 LRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLys 180
Cdd:COG1196    321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL-- 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  181 vlqqalgsacerrpelrgggdsvptpwgsdpdqngasrllkrgplltALSAEAVALALQKLHQDLWKAQQARDDLRDQVQ 260
Cdd:COG1196    399 -----------------------------------------------AAQLEELEEAEEALLERLERLEEELEELEEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  261 KLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkMEAQNDRELLQ 340
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL------LLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  341 ASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLA 420
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  421 QTLSNREREVETLQAEVQELEKQREmQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQR 500
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLRE-ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  501 DQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQR 580
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  581 VALTHLTLDLEERSQE-LQTQSSQLHELENHSTRL----------AKELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 649
Cdd:COG1196    745 EELLEEEALEELPEPPdLEELERELERLEREIEALgpvnllaieeYEELEERYDFLSEQREDLEEARETLEEAIEEIDRE 824


                   ....
gi 1958767521  650 GQEL 653
Cdd:COG1196    825 TRER 828
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 230-941 5.12e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 5.12e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  230 SAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQ-----VHSELQDLQRQLSQSQEEKSKWEGKQNSL 304
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  305 ESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASaagvleeDLRTARSALKLK 384
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-------DYREKLEKLKRE 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  385 NEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSRE 464
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  465 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRD-----------QIRELENDREAQRTALEHQL------------ 521
Cdd:TIGR02169  478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYATAIEVAAgnrlnnvvvedd 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  522 LDLEQKAQVIESQRG---------QIQDLKKQLGTLECL------------ALELEESHRKVEGQQKVITELEGQRELQ- 579
Cdd:TIGR02169  558 AVAKEAIELLKRRKAgratflplnKMRDERRDLSILSEDgvigfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRLMg 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  580 RVALTHLTLDLEERS---------------------QELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 638
Cdd:TIGR02169  638 KYRMVTLEGELFEKSgamtggsraprggilfsrsepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLERKGQELVLQKERI-QVLEDQRTLQTKILEEDLEQIKHSLR-ERGQELASQWQLMQERAEDGKSPSKAQ--R 714
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLeELEEDLSSLEQEIENVKSELKELEARiEELEEDLHKLEEALNDLEARLSHSRIPeiQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  715 GSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEakeqgelreqvL 794
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-----------L 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  795 QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLqEELIVEGRQ 874
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-EDPKGEDEE 945

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  875 VRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLqDSWLQAQATLAEQEQELEALRAE 941
Cdd:TIGR02169  946 IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILERIEE 1011
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
256-821 9.47e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 73.15  E-value: 9.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  256 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 335
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  336 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 415
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  416 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 495
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  496 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 575
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  576 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 655
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  656 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 735
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  736 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 815
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767521  816 RQEQQQ 821
Cdd:PRK02224   714 YDEAEE 719
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 6-445 1.64e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 1.64e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    6 QVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQ 85
Cdd:COG1196    310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   86 EAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QPENQAQAQLRSLYSVLQQALGSAcERRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLL--------TALSAEAVALA 237
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARL-LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigveaayeAALEAALAAAL 548

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  238 LQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQL-------SQSQEEKSKWEGKQNSLESELRD 310
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRTLV 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  311 LH------ETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLK 384
Cdd:COG1196    629 AArleaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767521  385 NEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE--------VETLQAEVQELEKQRE 445
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALeelpeppdLEELERELERLEREIE 777
PTZ00121 PTZ00121
MAEBL; Provisional
 30-842 1.74e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 1.74e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   30 EKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRelgvqvellrqeVKEKE 109
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK------------AEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  110 ADFVAREAQLLEELEASRIAERqvraslwAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVlqqalgsa 189
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAED-------AKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEA-------- 1217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  190 ceRRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDdlRDQVQKLVQRLTDT 269
Cdd:PTZ00121  1218 --RKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKAD 1293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  270 EAQKSQVHSELQDLQRQlsqsQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQ 349
Cdd:PTZ00121  1294 EAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  350 vehlQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 429
Cdd:PTZ00121  1370 ----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  430 VETLQAEVQELEKQREMQKAALELLSLD-LKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKlsvqrDQIRELEN 508
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  509 DREAQrtalehQLLDLEQKAQVIESQRGQiqDLKKQLGTLECLALELEESHRKVEGQQKVitelegqrelqrvalthltl 588
Cdd:PTZ00121  1521 AKKAD------EAKKAEEAKKADEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKA-------------------- 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  589 dlEERSQELQTQSSQLHELEnhstrlakelQERDQEVMSQRQqiEELQKQKEQLtqdleRKGQELVLQKERIQVLEDQRT 668
Cdd:PTZ00121  1573 --EEDKNMALRKAEEAKKAE----------EARIEEVMKLYE--EEKKMKAEEA-----KKAEEAKIKAEELKKAEEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  669 LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlkliLRDKEKEVECQQERIQELQEHMGQL 748
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---------AKKAEEDEKKAAEALKKEAEEAKKA 1704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  749 EQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEES 828
Cdd:PTZ00121  1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                          810
                   ....*....|....
gi 1958767521  829 MKQKTSALQAALEQ 842
Cdd:PTZ00121  1785 LDEEDEKRRMEVDK 1798
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-694 4.27e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.24  E-value: 4.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    6 QVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQ 85
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   86 EAQEGQRELGVQVELLRQEVKEKEADFVAREAQlLEELEASRIAERQVRASLwaqEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESR-LEELEEQLETLRSKVAQL---ELQIASLNNEIERLEARLERLEDRR 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QpenQAQAQLRSLYSVLQQALGSACERRPElrgggdsvptpwgsdpdqngasrLLKRGPLLTALSAEAVALALQKLHQDL 245
Cdd:TIGR02168  417 E---RLQQEIEELLKKLEEAELKELQAELE-----------------------ELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  246 WKAQQARDDLRDQVQKLVQRLTDTEAQKSQVH-------------SELQDLQRQLSQSQEEKSKWE-GKQNSLESELRDL 311
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSELISVDEGYEaAIEAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  312 ----HETMASLQSRLRQAELQK-----MEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE---------ED 373
Cdd:TIGR02168  551 vvenLNAAKKAIAFLKQNELGRvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  374 LRTARSALKLKNEE-----IESERERAQALQEQGELKVAQG--------KALQENLTLLAQTLSNREREVETLQAEVQEL 440
Cdd:TIGR02168  631 LDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSilerrreiEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  441 EKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQ 520
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  521 LLDLEQKAQVIESQ----RGQIQDLKKQLGTLECLALEL-----------EESHRKVEGQQKVITELEGQRELQRVALTH 585
Cdd:TIGR02168  791 IEQLKEELKALREAldelRAELTLLNEEAANLRERLESLerriaaterrlEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  586 LTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQV--- 662
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeys 950

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1958767521  663 --LEDQRTLQTKIlEEDLEQIKHSLRERGQELAS 694
Cdd:TIGR02168  951 ltLEEAEALENKI-EDDEEEARRRLKRLENKIKE 983
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
373-891 5.01e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.84  E-value: 5.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  373 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 445
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  446 MQKAALE--LLSLDLKKRSREV--DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 521
Cdd:PRK02224   290 ELEEERDdlLAEAGLDDADAEAveARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  522 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 601
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  602 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 667
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  668 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 741
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  742 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 820
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767521  821 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 891
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3-676 6.25e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 6.25e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    3 VTFQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQ 82
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   83 DIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRAS---LWAQEAKAAQLQLQLRSTEAQLE 159
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELeeqLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  160 ALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGdsvptpwgsdpdqngasrlLKRGPLLTALSAEAVALALQ 239
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE-------------------LEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  240 KLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVH-------------SELQDLQRQLSQSQEEKSKWE-GKQNSLE 305
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSELISVDEGYEaAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  306 SELRDL----HETMASLQSRLRQAELQK-----MEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE----- 371
Cdd:TIGR02168  545 GRLQAVvvenLNAAKKAIAFLKQNELGRvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  372 ----EDLRTARSALKLKNEE-----IESERERAQALQEQGELKVAQG--------KALQENLTLLAQTLSNREREVETLQ 434
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSilerrreiEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  435 AEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQR 514
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  515 TALEHQLLDLEQKAQVIESQ----RGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDL 590
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREAldelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  591 EERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrtLQ 670
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN--LQ 942


                   ....*.
gi 1958767521  671 TKILEE 676
Cdd:TIGR02168  943 ERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 629-1324 7.65e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.47  E-value: 7.65e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  629 RQQIEELQKQKEQLTQDLERKGQ----ELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQELASQW-QLMQERA 703
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAElrelELALLVLRLEELREEL-EELQEELKEAEEELEELTAELQELEEKLeELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  704 EDGKSPSKAQRGSLEHLKLIlRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEA 783
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI-SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  784 KEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR 863
Cdd:TIGR02168  357 EAELE----ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  864 LQEELIveGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQ 943
Cdd:TIGR02168  433 AELKEL--QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA----QLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  944 YSRQQEEAAFGQAE-----------------ALQEALSK-AQATLQEKEQR------LLEQAELS-CTLEASTATLQATL 998
Cdd:TIGR02168  507 GVKALLKNQSGLSGilgvlselisvdegyeaAIEAALGGrLQAVVVENLNAakkaiaFLKQNELGrVTFLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  999 DTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQeLCQKEEDLRQQDEQRQLLEKAV------------------AQ 1060
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG-GVLVVDDLDNALELAKKLRPGYrivtldgdlvrpggvitgGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1061 RSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEIL----MLREAQQRQNQEASSPSHRSFPAEKPSLQLLLA 1136
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEeleeELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1137 QQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 1216
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1217 -GPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRK 1295
Cdd:TIGR02168  826 lESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740
                   ....*....|....*....|....*....
gi 1958767521 1296 LkRDSLRASRAGSLEARETMNSSPTQQDG 1324
Cdd:TIGR02168  906 L-ESKRSELRRELEELREKLAQLELRLEG 933
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 22-755 2.04e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 2.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   22 RLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELL 101
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  102 RQEVKEKEADFVAREAQLLEELEASRIAErqvrASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQA-------Q 174
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELA----EELAELEEKLEELKEELESLEAELEELEAELEELESRLEeleeqleT 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  175 LRSLYSVLQQALGSACERRPELRGGGDSVptpwgsdpdqngASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDD 254
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEIERLEARLERL------------EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  255 LRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETM--ASLQSRLRQAELQKMEA 332
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  333 QNDREllqasKEKLSAQVEHLQACVTEARAQASAA------------GVLEEDLRTARSALKLKNEEIESERERAQALQE 400
Cdd:TIGR02168  532 DEGYE-----AAIEAALGGRLQAVVVENLNAAKKAiaflkqnelgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  401 QGELKVAQGKALQENLTLL--------AQTLSNREREVETL----------------------------QAEVQELEKQR 444
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLGGVlvvddldnALELAKKLRPGYRIvtldgdlvrpggvitggsaktnssilerRREIEELEEKI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  445 EMQKAALELLSLDLKKRSREVDLQqeqiqeleqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDL 524
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEEL----------EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  525 EQKAQVIESQRGQIQDLKKQLgtleclalelEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQL 604
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEEL----------AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  605 HELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEE------DL 678
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEElseelrEL 906

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521  679 EQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSL-EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGL 755
Cdd:TIGR02168  907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 252-1100 2.15e-11

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 69.21  E-value: 2.15e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  252 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEekskwegKQNSLESELRDLHETMASLQSRLRQAElqKME 331
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSA-------RESDLEQDYQAASDHLNLVQTALRQQE--KIE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  332 A-QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkv 406
Cdd:COG3096    351 RyQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAA---EEEVDSLKSQLADYQQALDVQQTRAiqyqQAVQ------- 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  407 AQGKAlQENLTLLAQTLSNREREVETLQAEVQELEKQRemqkaalellsLDLKKRSREVDLQQEQIQELEQcrsVLEHLP 486
Cdd:COG3096    421 ALEKA-RALCGLPDLTPENAEDYLAAFRAKEQQATEEV-----------LELEQKLSVADAARRQFEKAYE---LVCKIA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  487 MAVqEREQKLSVQRDQIRELENDRE--AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEG 564
Cdd:COG3096    486 GEV-ERSQAWQTARELLRRYRSQQAlaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEA 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  565 QQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQER---DQEVMSQRQQIEELQKQKEQ 641
Cdd:COG3096    565 QLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATV 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  642 LTQDLERKGQELVLQKERIQVL---EDQRTLQTK---------------------------------ILEEDLEQIKHSL 685
Cdd:COG3096    645 ERDELAARKQALESQIERLSQPggaEDPRLLALAerlggvllseiyddvtledapyfsalygparhaIVVPDLSAVKEQL 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  686 RERGQELASQWQLmqERAEDGKSPSKAQRGSLEHLKLIlrdKEKEVECQQERIQEL--------QEHMGQLEQQLQGLHR 757
Cdd:COG3096    725 AGLEDCPEDLYLI--EGDPDSFDDSVFDAEELEDAVVV---KLSDRQWRYSRFPEVplfgraarEKRLEELRAERDELAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  758 KVGETSLllthREQEtatlQQRLQEAKEQ--GELREQVLQGQLEEAQRALAQR----DHELEALRQEQQQTRGQEESMKQ 831
Cdd:COG3096    800 QYAKASF----DVQK----LQRLHQAFSQfvGGHLAVAFAPDPEAELAALRQRrselERELAQHRAQEQQLRQQLDQLKE 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  832 KTSALQAALEQAHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQA 907
Cdd:COG3096    872 QLQLLNKLLPQANLladeTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQR 951

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  908 QEH-------EAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQ 980
Cdd:COG3096    952 RLKqqifalsEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAK 1031

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  981 AELSCTLEASTATLQATLDT-----CQARARQLEEAL---RVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQ 1052
Cdd:COG3096   1032 QQTLQELEQELEELGVQADAeaeerARIRRDELHEELsqnRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767521 1053 -------LLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE 1100
Cdd:COG3096   1112 qakagwcAVLRLARDNDVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEH 1166
PTZ00121 PTZ00121
MAEBL; Provisional
 639-1313 7.80e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 7.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLERKGQELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQElaSQWQLMQERAEDGKSPSKAQRGSLE 718
Cdd:PTZ00121  1043 KEKDIIDEDIDGNHEGKAEAKAHVGQDEG-LKPSYKDFDFDAKEDNRADEATE--EAFGKAEEAKKTETGKAEEARKAEE 1119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETAtlqQRLQEAKEQGELREQVLQGQL 798
Cdd:PTZ00121  1120 AKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDA---KKAEAARKAEEVRKAEELRKA 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRALAQRDHE----LEALRQEQQQTRGQ-----EESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR-LQEEL 868
Cdd:PTZ00121  1197 EDARKAEAARKAEeerkAEEARKAEDAKKAEavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAaIKAEE 1276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  869 IVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE--QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 946
Cdd:PTZ00121  1277 ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  947 QQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleASTATLQATLDTCQARARQLEEALRVREGEIQTQALQH 1026
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK------ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEK 1430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1027 QEAmqhlqQELCQKEEDLRQQDE-QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 1105
Cdd:PTZ00121  1431 KKA-----DEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA 1505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1106 REAQQRQNQEASSpshrsfpAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQE--IAM 1183
Cdd:PTZ00121  1506 AEAKKKADEAKKA-------EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedKNM 1578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1184 FLQASVLERESEQQRLQEELVLSRQALE---EQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLER 1260
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKmkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE 1658

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767521 1261 LQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAGSLEARE 1313
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 575-902 1.55e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 1.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  575 QRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQdlerkgqelv 654
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  655 lqkeriqvlEDQRTLQTKI--LEEDLEQIKHSLRERGQELasqwQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVE 732
Cdd:TIGR02169  287 ---------EEQLRVKEKIgeLEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  733 CQQERIQELQEHMGQLEQQLQGLHRKVGETslllthrEQETATLQQRLQEAKEqgelreqvlqgQLEEAQRALAQRDHEL 812
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAET-------RDELKDYREKLEKLKR-----------EINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  813 EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREH 892
Cdd:TIGR02169  416 QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          330
                   ....*....|
gi 1958767521  893 EKTVLALQQR 902
Cdd:TIGR02169  496 EAQARASEER 505
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 247-951 2.57e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  247 KAQQARDDLRDQVQKLVQRLtdtEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDL----------HETMA 316
Cdd:pfam15921  135 RESQSQEDLRNQLQNTVHEL---EAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFeeasgkkiyeHDSMS 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  317 SLQSRLRQAELQKMEAQNDREL--LQASKEKLSAQVEHLQacvteARAQASAAGVLEEDLRTARSALKLKNEEI-----E 389
Cdd:pfam15921  212 TMHFRSLGSAISKILRELDTEIsyLKGRIFPVEDQLEALK-----SESQNKIELLLQQHQDRIEQLISEHEVEItglteK 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  390 SERERAQALQEQGELKVAQGKALQENLTLLAQtLSNREREVETLQAEVQELEKQREMQKAALE-LLSLDLKKRSREVDLQ 468
Cdd:pfam15921  287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQ-LSDLESTVSQLRSELREAKRMYEDKIEELEkQLVLANSELTEARTER 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  469 QEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL-GT 547
Cdd:pfam15921  366 DQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  548 LECLALELEESHRKVEGQQKVITELEGQRELQRVALthltldleersQELQTQSSQLHELENHSTRLAKELQERDQEVMS 627
Cdd:pfam15921  446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVV-----------EELTAKKMTLESSERTVSDLTASLQEKERAIEA 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  628 QRQQIEELQKQ---KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 704
Cdd:pfam15921  515 TNAEITKLRSRvdlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQ 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  705 DGKSPSKaQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAK 784
Cdd:pfam15921  595 LEKEIND-RRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  785 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRL 864
Cdd:pfam15921  674 EDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFL 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  865 QEELIVEGRQVRALEEVLGDLRAESreheKTVLALQQRCAEQAQEHEAEARTLQDSwlQAQATLAEQEQELEALRAENQY 944
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQEL----STVATEKNKMAGELEVLRSQERRLKEK--VANMEVALDKASLQFAECQDII 827


                   ....*..
gi 1958767521  945 SRQQEEA 951
Cdd:pfam15921  828 QRQEQES 834
PTZ00121 PTZ00121
MAEBL; Provisional
 490-1216 2.90e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.55  E-value: 2.90e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  490 QEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV--IESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 567
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETgkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  568 viTELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnhsTRLAKELQERDQ-------EVMSQRQQIEELQKQKE 640
Cdd:PTZ00121  1148 --AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAEELRKAEDarkaeaaRKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  641 QLTQDLERKGQELVLQKERIQVLEDQRTLQtKILEEDLEQIKHSLRERGQELASQWQLMQE--RAEDGKSPSKAQRGslE 718
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNE-EIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKA--E 1299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLILRDKEKEVEcqQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQvlqgQL 798
Cdd:PTZ00121  1300 EKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK----KK 1373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRalaqrdhELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 878
Cdd:PTZ00121  1374 EEAKK-------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  879 EEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQatlaEQEQELEALRAENQYSRQQEEAAFGQAEA 958
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE----EAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  959 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEE----ALRVREGEIQTQALQHQEAMQHLQ 1034
Cdd:PTZ00121  1523 KADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmALRKAEEAKKAEEARIEEVMKLYE 1602

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1035 QELCQKEEDLRQQDEQR---QLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEE----ILMLRE 1107
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKikaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKK 1682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1108 AQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREI---EWREKAQGLALSLAQSKASISSLQEIAMF 1184
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIkaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHL 1762

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1958767521 1185 LQASvlERESEQQRLQEELVLSRQALEEQQSR 1216
Cdd:PTZ00121  1763 KKEE--EKKAEEIRKEKEAVIEEELDEEDEKR 1792
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 238-1055 1.31e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 1.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  238 LQKLHQDLWKAQQARDDLRDQVQK-LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkskwegkqnsleseLRDLHETMA 316
Cdd:TIGR02169  203 LRREREKAERYQALLKEKREYEGYeLLKEKEALERQKEAIERQLASLEEELEKLTEE--------------ISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  317 SLQSRLRQAELQKMEAQNDREL-LQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERA 395
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  396 QALQEQgelkvaqgkalqenltlLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL 475
Cdd:TIGR02169  349 RKRRDK-----------------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  476 EQcrsVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALEL 555
Cdd:TIGR02169  412 QE---ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  556 EESHRKVEGQQKVIteleGQRELQRVALTHLtldLEERSQELQTQSSQLHEL-ENHSTRLAKELQERDQEVMSQRqqiEE 634
Cdd:TIGR02169  489 QRELAEAEAQARAS----EERVRGGRAVEEV---LKASIQGVHGTVAQLGSVgERYATAIEVAAGNRLNNVVVED---DA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  635 LQKQKEQLTQDlERKGQELVLQKERIQvleDQRTLQTKILEEDLEQIKHSLRERGQELAS------QWQLMQERAEDGK- 707
Cdd:TIGR02169  559 VAKEAIELLKR-RKAGRATFLPLNKMR---DERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvfGDTLVVEDIEAARr 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  708 ---------------SPSKAQRG---SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHR 769
Cdd:TIGR02169  635 lmgkyrmvtlegelfEKSGAMTGgsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  770 EQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ-----AH 844
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQE----EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  845 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHE---AEARTLQDSW 921
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  922 LQAQATLAEQEQELEAL-----RAENQYSRQQE--EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 994
Cdd:TIGR02169  871 EELEAALRDLESRLGDLkkerdELEAQLRELERkiEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767521  995 qATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLE 1055
Cdd:TIGR02169  951 -LSLEDVQAELQRVEEEIR-ALEPVNMLAIQEYEEVLKRLDELKEKRAKL--EEERKAILE 1007
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 483-1297 2.11e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.44  E-value: 2.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  483 EHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtleclaleLEESHRKV 562
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  563 EGQ-QKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHEL--------------------------ENHSTRLA 615
Cdd:pfam15921  144 RNQlQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeeasgkkiyehdsmstmhfRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  616 KELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQ-KERIQVLEDQRTLQTKILEEDleqiKHSLRERGQELAS 694
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEK----ASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  695 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 774
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  775 TLQQRLQEAKEQGELREQVLQGQLEEAQRaLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlkERQGEL 854
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS------ECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  855 EEHRGQVQRLQEELivegrqvraleEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQE 934
Cdd:pfam15921  447 ERQMAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  935 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQlEEALRV 1014
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT-AGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1015 REGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEkaVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLT 1094
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1095 VAQKEEEILMLREAQQRQNQEASSPSHrsfpaeKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKAS 1174
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTN------KLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ 742

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1175 ISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALeeqqsrgphsssradqgpkagqdtepgEVIEAEPSPGVGEKEQL 1254
Cdd:pfam15921  743 IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL---------------------------STVATEKNKMAGELEVL 795

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767521 1255 RQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLK 1297
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 6-545 2.43e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 2.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    6 QVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQ 85
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   86 EAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRA---SLWAQEAKAAQLQLQLRSTEAQLEALV 162
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaeeELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  163 AEQQPENQAQAQLRSLYSVLQQALGSACERRPELRgggdsvptpwgsdpdqnGASRLLKRGPLLTALSAEAVALALQKLH 242
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEE-----------------EALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  243 QDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ-----EEKSKWEGKQNSLESELRD------L 311
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglaGAVAVLIGVEAAYEAALEAalaaalQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  312 HETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALklkNEEIESE 391
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG---DTLLGRT 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  392 RERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQ 471
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521  472 IQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEqkaqVIESQRGQIQDLKKQL 545
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP----DLEELERELERLEREI 776
PTZ00121 PTZ00121
MAEBL; Provisional
 25-680 2.45e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   25 KQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRllvlqeADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQ- 103
Cdd:PTZ00121  1207 KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKK------AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKa 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  104 -EVKEKEADFVAREAQLLEELEASRIAERQvraslwAQEAKAAQlQLQLRSTEAQLEALVAEQQPENQAQAQlrslysvl 182
Cdd:PTZ00121  1281 dELKKAEEKKKADEAKKAEEKKKADEAKKK------AEEAKKAD-EAKKKAEEAKKKADAAKKKAEEAKKAA-------- 1345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  183 QQALGSACERRPELRgggdsvptpwgsdpdqngASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDlRDQVQKL 262
Cdd:PTZ00121  1346 EAAKAEAEAAADEAE------------------AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK-AEEDKKK 1406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  263 VQRLTDTEAQKSQVhSELQDLQRQLSQSQEEKSKWEGKQNSleSELRDLHETMASLQSRLRQAElqkmEAQNDRELLQAS 342
Cdd:PTZ00121  1407 ADELKKAAAAKKKA-DEAKKKAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKAE----EAKKADEAKKKA 1479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  343 KEKLSAqvEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTlLAQT 422
Cdd:PTZ00121  1480 EEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK-KAEE 1556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  423 LSNREREVETLQAEVQELEKQREMQKAalELLSLDLKKRSREVdlqqeqiqeleqcrsvlehlpMAVQEREQKLSVQRDQ 502
Cdd:PTZ00121  1557 LKKAEEKKKAEEAKKAEEDKNMALRKA--EEAKKAEEARIEEV---------------------MKLYEEEKKMKAEEAK 1613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  503 IRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtLECLALELEESHRKVEGQQKVITELEGQRELQRVA 582
Cdd:PTZ00121  1614 KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA---EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  583 LTHLTLDLEERSQELQTQSSQLHELENhSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQV 662
Cdd:PTZ00121  1691 AEALKKEAEEAKKAEELKKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769

                          650
                   ....*....|....*...
gi 1958767521  663 LEDQRTLQTKILEEDLEQ 680
Cdd:PTZ00121  1770 AEEIRKEKEAVIEEELDE 1787
PTZ00121 PTZ00121
MAEBL; Provisional
 270-882 3.02e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 3.02e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  270 EAQKSQVHSELQDLQR--QLSQSQEEKSKWEGKQNSLE----SELRDLHETMASLQSRLRQA----ELQKMEAQNDRELL 339
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKaeEAKKDAEEAKKAEEERNNEEirkfEEARMAHFARRQAAIKAEEArkadELKKAEEKKKADEA 1295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  340 QASKEKlsAQVEHLQACVTEARAQASAAGVLEEDLRTArSALKLKNEEiesERERAQALQEQGELKVAQGKALQENLTLL 419
Cdd:PTZ00121  1296 KKAEEK--KKADEAKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEE---AKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  420 AQTLSNREREVETLQAEVQELEKQREMQKAALELlsldlKKRSREVDLQQEQIQELEQCRSVLEHLPMAvqEREQKLSVQ 499
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-----KKKADELKKAAAAKKKADEAKKKAEEKKKA--DEAKKKAEE 1442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  500 RDQIRELENDREAQRTALEhqlldLEQKAQviesQRGQIQDLKKQlgtlECLALELEESHRKVEGQQKVITELEGQRELQ 579
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEE-----AKKKAE----EAKKADEAKKK----AEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  580 RVALthltldlEERSQELQTQSSQLHELEnhstrlakelqerdqevmsQRQQIEELQKQKEQLTQDLERKGQELVLQKER 659
Cdd:PTZ00121  1510 KKAD-------EAKKAEEAKKADEAKKAE-------------------EAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  660 IQVLEDQRTLQTKILE----EDLEQIKHSLRERGQELASQWQLMqeRAEDGKSPSKAqRGSLEHLKlilrdKEKEVECQQ 735
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMAlrkaEEAKKAEEARIEEVMKLYEEEKKM--KAEEAKKAEEA-KIKAEELK-----KAEEEKKKV 1635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  736 ERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 815
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  816 RQeQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGElEEHRGQVQRLQEELIVEGRQVRALEEVL 882
Cdd:PTZ00121  1716 KK-AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
mukB PRK04863
chromosome partition protein MukB;
262-1102 7.21e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 60.74  E-value: 7.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  262 LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElQKMEAQNDRELLQA 341
Cdd:PRK04863   284 HLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQE-KIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  342 SKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkvaqgkALQENLT 417
Cdd:PRK04863   363 RLEEQNEVVEEADEQQEENEARAEAA---EEEVDELKSQLADYQQALDVQQTRAiqyqQAVQ-----------ALERAKQ 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  418 LLAQ---TLSNREREVETLQAEVQElekqremqkAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEhlpmavQEREQ 494
Cdd:PRK04863   429 LCGLpdlTADNAEDWLEEFQAKEQE---------ATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGE------VSRSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  495 KLSVQRDQIRELENDR--EAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITEL 572
Cdd:PRK04863   494 AWDVARELLRRLREQRhlAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSES 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  573 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAK---ELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 649
Cdd:PRK04863   574 VSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREqsgEEFEDSQDVTEYMQQLLERERELTVERDELAAR 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  650 GQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHS-------LRERGQELASQWQLMQ----ERAEDGKSPSKAQRGSLE 718
Cdd:PRK04863   654 KQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSeiyddvsLEDAPYFSALYGPARHaivvPDLSDAAEQLAGLEDCPE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLKLI------LRDKEKEVE-----------------------------CQQERIQELQEHMGQLEQQLQGLHRKVGETS 763
Cdd:PRK04863   734 DLYLIegdpdsFDDSVFSVEelekavvvkiadrqwrysrfpevplfgraAREKRIEQLRAEREELAERYATLSFDVQKLQ 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  764 LLLTHREQETAT-LQQRLQEAKEQgelreqvlqgQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 842
Cdd:PRK04863   814 RLHQAFSRFIGShLAVAFEADPEA----------ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPR 883

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  843 AHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEktvlalqqrcaeqaqeheaearTLQ 918
Cdd:PRK04863   884 LNLladeTLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFE----------------------QLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  919 DSWLQAQATLAEQEQELEALRAENqysrqQEEAAFGQAEAlQEALSKAQAtLQEKEQRLLEQAELSCTlEASTATLQAtl 998
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTEVV-----QRRAHFSYEDA-AEMLAKNSD-LNEKLRQRLEQAEQERT-RAREQLRQA-- 1011

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  999 dtcQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQR--QLLEKAVAQRSQENGIQEKQSLEqe 1076
Cdd:PRK04863  1012 ---QAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARrdELHARLSANRSRRNQLEKQLTFC-- 1086

                          890       900
                   ....*....|....*....|....*.
gi 1958767521 1077 kEEETRGLLESLKELQLTVAQKEEEI 1102
Cdd:PRK04863  1087 -EAEMDNLTKKLRKLERDYHEMREQV 1111
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
736-940 1.02e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  736 ERIQELQEHMGQLEqqlqGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 815
Cdd:COG4913    225 EAADALVEHFDDLE----RAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  816 RQEQQQTRGQEESMKQKTSALQAALEQAHVT---------------LKERQGELEEHRGQVQRLQEELIVEGRQVRALEE 880
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQirgnggdrleqlereIERLERELEERERRRARLEALLAALGLPLPASAE 380

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  881 VLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARtlqdswlQAQATLAEQEQELEALRA 940
Cdd:COG4913    381 EFAALRAEAAALLEALEEELEALEEALAEAEAALR-------DLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 24-805 1.06e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   24 VKQEIEEKVREAQECSRIQK-ELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLR 102
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  103 QEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVL 182
Cdd:TIGR02169  276 ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  183 QQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLL------KRGPLLTALSaeAVALALQKLHQDLWKAQQARDDLR 256
Cdd:TIGR02169  356 TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKleklkrEINELKRELD--RLQEELQRLSEELADLNAAIAGIE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  257 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 336
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  337 ELLQASKEKLSAQVEHL------QACVTEARAQASAAGVLEEDLRTARSALKLKNE------------EIESERERAQAL 398
Cdd:TIGR02169  514 EVLKASIQGVHGTVAQLgsvgerYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  399 QEQGELKVAQgkalqeNLTLLAQTLSNREREVETLQAEVQELEKQRE-MQKAALELLSLDLKKRSRE-VDLQQEQIQELE 476
Cdd:TIGR02169  594 SEDGVIGFAV------DLVEFDPKYEPAFKYVFGDTLVVEDIEAARRlMGKYRMVTLEGELFEKSGAmTGGSRAPRGGIL 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  477 QCRSVLEHLPMaVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDlkkqlgtleclalELE 556
Cdd:TIGR02169  668 FSRSEPAELQR-LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ-------------EEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  557 ESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRlaKELQERDQEVMSQRQQIEELQ 636
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  637 KQKEQLTQDLERKGQELVLQKERIQVLEDQRtlqtkileEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS 716
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQEQR--------IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  717 LEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLqg 796
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQ-- 961


                   ....*....
gi 1958767521  797 QLEEAQRAL 805
Cdd:TIGR02169  962 RVEEEIRAL 970
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 221-450 4.24e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 4.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  221 KRGPLLTALSAEAVALALQKLHQDlwkAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGK 300
Cdd:COG4942      1 MRKLLLLALLLALAAAAQADAAAE---AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  301 QNSLESELRDLHETMASLQSRLRQ---------AELQKMEAQNDRELLQASK---------EKLSAQVEHLQACVTEARA 362
Cdd:COG4942     78 LAALEAELAELEKEIAELRAELEAqkeelaellRALYRLGRQPPLALLLSPEdfldavrrlQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  363 QASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEK 442
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEA 234


                   ....*...
gi 1958767521  443 QREMQKAA 450
Cdd:COG4942    235 EAAAAAER 242
PTZ00121 PTZ00121
MAEBL; Provisional
 268-975 6.66e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 6.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  268 DTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKME----AQNDRELLQASK 343
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEearkAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  344 EKLSAQVEHLQACVTEARAQASAAGV---------LEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQE 414
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEevrkaeelrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  415 NLTLLAQTLSNREREVETLQAEVQELEKQREMQKAAlELLSLDLKKRSREVDLQQEQIQELEQCRSvlehlpmavqEREQ 494
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEKKKADEAKKAEEKKKA----------DEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  495 KLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtlECLALELEESHRKVEGQQKVITELEG 574
Cdd:PTZ00121  1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  575 QRELQRVALthltlDLEERSQELQTQSSQLHELENHSTRlAKELQERDQEVmsqrQQIEELQKQKEQltqdlERKGQELV 654
Cdd:PTZ00121  1386 KAEEKKKAD-----EAKKKAEEDKKKADELKKAAAAKKK-ADEAKKKAEEK----KKADEAKKKAEE-----AKKADEAK 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  655 LQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLilRDKEKEVECQ 734
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA--EEAKKADEAK 1528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  735 QERIQELQEHMGQLEQQLQGLHRKVGETsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEA 814
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEE---LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  815 LRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 894
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  895 TvlalQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKE 974
Cdd:PTZ00121  1686 D----EKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757


                   .
gi 1958767521  975 Q 975
Cdd:PTZ00121  1758 K 1758
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
853-1046 7.11e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 7.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  853 ELEEHRGQVQRLQEELIVEGRQVRALEEVLGD------LRAESREHEKTVLALQQRCAEQAQEH-EAEARTLQDSWLQAQ 925
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELaeryaaARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  926 ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR 1004
Cdd:COG4913    309 AELERLEARLDALREElDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1958767521 1005 ARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 1046
Cdd:COG4913    389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 360-1084 7.90e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 7.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  360 ARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQE-QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 438
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  439 ELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL------------EQCRSVLEHLPMAVQ---EREQKLSVQRD-- 501
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigeleaeiASLERSIAEKERELEdaeERLAKLEAEIDkl 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  502 --QIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEeshRKVEGQQKVITELEGQRELQ 579
Cdd:TIGR02169  335 laEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  580 RVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELV-LQKE 658
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSkLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  659 RIQVLEDQRTLQT---------KILEEDLEQIKHSLRERGQeLASQWQLMQERAEDGKSPS----------------KAQ 713
Cdd:TIGR02169  492 LAEAEAQARASEErvrggraveEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRLNNvvveddavakeaiellKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  714 RGS------LEHLKLILRDKEKE------------VECQQ----------------ERIQELQEHMGQ-----LEQQL-- 752
Cdd:TIGR02169  571 KAGratflpLNKMRDERRDLSILsedgvigfavdlVEFDPkyepafkyvfgdtlvvEDIEAARRLMGKyrmvtLEGELfe 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  753 -----QGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 827
Cdd:TIGR02169  651 ksgamTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE----LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  828 SMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREhektvlalqqrcaEQA 907
Cdd:TIGR02169  727 QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-------------SRI 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  908 QEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTL 987
Cdd:TIGR02169  794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  988 EASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGI 1067
Cdd:TIGR02169  874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL 953

                          810
                   ....*....|....*..
gi 1958767521 1068 QEKQSLEQEKEEETRGL 1084
Cdd:TIGR02169  954 EDVQAELQRVEEEIRAL 970
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 764-1216 1.48e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 1.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  764 LLLTHREQETATLQQRLQEAKEQGELREQVlqGQLEEAQRALAQ-----RDH---ELEALRQEQQQTRGQEEsmkqkTSA 835
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMAREL--EELSARESDLEQdyqaaSDHlnlVQTALRQQEKIERYQED-----LEE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  836 LQAALEQAHVTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDL-RAESREHEKtvlALQQRCAEQAQEheaea 914
Cdd:COG3096    359 LTERLEEQEEVVEEAAEQLAEAEARLEAAEEE-------VDSLKSQLADYqQALDVQQTR---AIQYQQAVQALE----- 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  915 rtlqdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLleqaELSCTLEASTATL 994
Cdd:COG3096    424 --------KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAY----ELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  995 QAtldtcQARARQLEEALRvregeiqtqALQHQ-EAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSL 1073
Cdd:COG3096    492 QA-----WQTARELLRRYR---------SQQALaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQ--LDAAEEL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1074 EQEKEEETrglleslkelqltvAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllAQQDLERLQNALRQTEAR 1153
Cdd:COG3096    556 EELLAELE--------------AQLEELEEQAAEAVEQRSE---------------------LRQQLEQLRARIKELAAR 600

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767521 1154 EIEWREKAQGLALSLAQSKASISSLQEIAMFLQaSVLERESEQQRLQEELVLSRQALEEQQSR 1216
Cdd:COG3096    601 APAWLAAQDALERLREQSGEALADSQEVTAAMQ-QLLEREREATVERDELAARKQALESQIER 662
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
615-1097 1.63e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  615 AKELQERDQEVMSQRQQIEELQKQKEQLTQdLERKGQELVLQKERIQVLEDQRTLQTKileEDLEQIKHSLRERGQELAS 694
Cdd:COG4913    227 ADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRL---WFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  695 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDK--------EKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 766
Cdd:COG4913    303 ELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  767 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ-------EQQQTRGQ-EESMKQKTSAL-- 836
Cdd:COG4913    383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDAlAEALGLDEAELpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  837 --------------QAALEQA------------------------------HVTLKERQGELEEHRGQV--QRLQEELIV 870
Cdd:COG4913    463 vgelievrpeeerwRGAIERVlggfaltllvppehyaaalrwvnrlhlrgrLVYERVRTGLPDPERPRLdpDSLAGKLDF 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  871 EGRQVRA-LEEVLG------------DLRAESR-------------EHEK-------TVLALQQRCAEQAQEHEAEARTL 917
Cdd:COG4913    543 KPHPFRAwLEAELGrrfdyvcvdspeELRRHPRaitragqvkgngtRHEKddrrrirSRYVLGFDNRAKLAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  918 QDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQealskAQATLQEKEQRLLEQAELSCTLEAstatLQAT 997
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS-----AEREIAELEAELERLDASSDDLAA----LEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  998 LDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEE-DLRQQDEQRQLLEKAVAQRSQENGIQE-KQSLEQ 1075
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERFAAALGDAVERElRENLEE 773

                          570       580
                   ....*....|....*....|..
gi 1958767521 1076 EKEEETRGLLESLKELQLTVAQ 1097
Cdd:COG4913    774 RIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
429-980 2.73e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  429 EVETLQAEVQELEK-QREMQKAA--LELLSlDLKKRSREVDLQQEQIQELEQCRSVLEHlpmavQEREQKLSVQRDQIRE 505
Cdd:COG4913    226 AADALVEHFDDLERaHEALEDAReqIELLE-PIRELAERYAAARERLAELEYLRAALRL-----WFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  506 LENDR---EAQRTALEHQLLDLEQKAQVIESQR-----GQIQDLKKQLGTLECLALELEESHRKVEGQQKVI-----TEL 572
Cdd:COG4913    300 LRAELarlEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAALglplpASA 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  573 EGQRELQRVALTHLtldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQI----EELQKQKEQLTQDLER 648
Cdd:COG4913    380 EEFAALRAEAAALL----EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  649 KGQELVLQKERIQVLEDQ-----------RTLQTKIL--EEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPsKAQRG 715
Cdd:COG4913    456 DEAELPFVGELIEVRPEEerwrgaiervlGGFALTLLvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERP-RLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  716 SLEHlKLILRDKEKEvecqqeriQELQEHMGQleqqlQGLHRKVGETSLLLTHREQETATLQ----QRLQEAKEQGELRE 791
Cdd:COG4913    535 SLAG-KLDFKPHPFR--------AWLEAELGR-----RFDYVCVDSPEELRRHPRAITRAGQvkgnGTRHEKDDRRRIRS 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  792 QVLQGQleEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE--QAHVTLKERQGELEEHRGQVQRLQEE-- 867
Cdd:COG4913    601 RYVLGF--DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAEle 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  868 -LIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEaEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 946
Cdd:COG4913    679 rLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLEERFAA 757

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1958767521  947 QQEEAAFGQ-AEALQEALSKAQATLQEKEQRLLEQ 980
Cdd:COG4913    758 ALGDAVERElRENLEERIDALRARLNRAEEELERA 792
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 632-977 3.22e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 3.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  632 IEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTLQTKILEEDLEQIKH--SLRERGQELAsQWQLMQERaedgksp 709
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENI----ERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYE-GYELLKEK------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  710 sKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKV----GETSLLLTHREQETATLQQRLQEAKE 785
Cdd:TIGR02169  233 -EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  786 QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQ 865
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  866 EELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEALRAENQYS 945
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958767521  946 RQQEEAAFGQAEALQEALSKAQATLQEKEQRL 977
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
PTZ00121 PTZ00121
MAEBL; Provisional
 371-1093 3.30e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 3.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  371 EEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAA 450
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  451 lELLSLDLKKRSREVDLQQEQIQEleqcrsvlEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV 530
Cdd:PTZ00121  1174 -DAKKAEAARKAEEVRKAEELRKA--------EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  531 IESQRGQIQDLKKQlgtlECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnh 610
Cdd:PTZ00121  1245 AEEERNNEEIRKFE----EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-- 1318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  611 stRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEdlEQIKHSLRERGQ 690
Cdd:PTZ00121  1319 --EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  691 ELASQWQLMQERAEDGKSPSKAQRGSLEhlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHRE 770
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADE-----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  771 QETATLQQRLQEAKEQGELREQVLQGQ--LEEAQRALAQRDHELEALRQEQ----QQTRGQEESMK-------------- 830
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEakkaDEAKKAEEAKKadeakkaeekkkad 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  831 --QKTSALQAALEQAHVTLKERQgelEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQAQ 908
Cdd:PTZ00121  1550 elKKAEELKKAEEKKKAEEAKKA---EEDKNMALRKAEEA-------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  909 EHEAEARTLQDswLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLE 988
Cdd:PTZ00121  1620 IKAEELKKAEE--EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  989 ASTATLQATLDTCQARARQLEEALRVREGEIQTQAlqhqeamqhlqqelcqkEEDLRQQDEQRQLLEKAVAQRSQENGIQ 1068
Cdd:PTZ00121  1698 AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-----------------EEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760

                          730       740
                   ....*....|....*....|....*
gi 1958767521 1069 EKQSLEQEKEEETRGLLESLKELQL 1093
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEEL 1785
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
658-1115 3.81e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 3.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  658 ERIQVLEDQRTLQTKILEEDLEQikhslRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER 737
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQ-----REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  738 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelreqvlqgqLEEAQRALAQRDHELEALRQ 817
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR-----------LEECRVAAQAHNEEAESLRE 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  818 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRaESREHEKTVL 897
Cdd:PRK02224   350 DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR-EERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  898 ALQQRCAEQAQEHEAEARTLQDSWLQAQ-----------ATLAEQEQELEALRAENQYSRQQEEAAFGQAEALqEALSKA 966
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGKCPEcgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  967 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQH---LQQELCQKEED 1043
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKER 587

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767521 1044 LRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRgllESLKELQLTVAQKEEEILMLREAQQRQNQE 1115
Cdd:PRK02224   588 IESLERIRTLLAAIADAEDEIERLREKREALAELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKE 656
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 491-1217 5.04e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 5.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  491 EREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQ-IQDLKKQLGTLECLALELEESHRKVEGQQKVI 569
Cdd:pfam02463  195 LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKEN 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  570 TELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErk 649
Cdd:pfam02463  275 KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE-- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  650 gqelvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS---LEHLKLILRD 726
Cdd:pfam02463  353 -----AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELArqlEDLLKEEKKE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  727 KEKEVECQQERIQELQEHMGQLEQQLQglhrKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALA 806
Cdd:pfam02463  428 ELEILEEEEESIELKQGKLTEEKEELE----KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  807 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRgqvqrlqEELIVEGRQVRALEEVLGDLR 886
Cdd:pfam02463  504 KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA-------TADEVEERQKLVRALTELPLG 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  887 AESREHEKTVLalqqRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENqySRQQEEAAFGQAEALQEALSKA 966
Cdd:pfam02463  577 ARKLRLLIPKL----KLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI--LKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  967 QATLQEKeqrLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 1046
Cdd:pfam02463  651 GVSLEEG---LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1047 QDEQRQLLEKAVAQRSQENGIQEKqslEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPA 1126
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1127 EKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLS 1206
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730
                   ....*....|.
gi 1958767521 1207 RQALEEQQSRG 1217
Cdd:pfam02463  885 KDELESKEEKE 895
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 854-1181 6.34e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.29  E-value: 6.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  854 LEEHRGQVQRLQeelivegRQVRALEEVLgDLRAESREHEKTVLALQ-QRCAEQAQEHEAEARTLQDSWLQAQATLAEQE 932
Cdd:TIGR02168  195 LNELERQLKSLE-------RQAEKAERYK-ELKAELRELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  933 QELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEAL 1012
Cdd:TIGR02168  267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1013 RVREGEIQTQALQHQEAmQHLQQELCQKEEDLRQQDEQrqllekavaQRSQENGIQEKQSLEQEKEEETRGLLESLKELQ 1092
Cdd:TIGR02168  347 EELKEELESLEAELEEL-EAELEELESRLEELEEQLET---------LRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1093 LTVAQKEEEILMLREAQQRQNQEASSPSHRsfpaekpsLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSK 1172
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELE--------EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488


                   ....*....
gi 1958767521 1173 ASISSLQEI 1181
Cdd:TIGR02168  489 ARLDSLERL 497
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 797-1023 6.58e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 6.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  797 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 876
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  877 ALEEVLGDLRAE---SREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAF 953
Cdd:COG4942    101 AQKEELAELLRAlyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  954 GQAEALQEALSKAQAtlqekeqrllEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQA 1023
Cdd:COG4942    181 AELEEERAALEALKA----------ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 321-1167 7.76e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 7.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  321 RLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQE 400
Cdd:pfam02463  193 EELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  401 QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRS 480
Cdd:pfam02463  273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  481 VLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEEShr 560
Cdd:pfam02463  353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELE-- 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  561 KVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKE 640
Cdd:pfam02463  431 ILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  641 QLtqDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHL 720
Cdd:pfam02463  511 VL--LALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLK 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  721 KLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELReqvlqGQLEE 800
Cdd:pfam02463  589 LPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGL-----AEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  801 AQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEE 880
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  881 VLGDLRAESREHE-KTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEAL 959
Cdd:pfam02463  744 KIDEEEEEEEKSRlKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  960 QEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQ 1039
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELE 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1040 KEEDLRQQDEQRQLLEKAVAQRSQENGIQEK---------QSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQ 1110
Cdd:pfam02463  904 EESQKLNLLEEKENEIEERIKEEAEILLKYEeepeellleEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEF 983

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1111 RQNQEASSPSHR---SFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALS 1167
Cdd:pfam02463  984 EEKEERYNKDELekeRLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELG 1043
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 84-951 9.04e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 9.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   84 IQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVA 163
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  164 EQQPENQAQAQLRSLYSVLQQALGSACERRPELrgggdsvptpwGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQ 243
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLL-----------AKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  244 DLWKAQQARDDLRDQVQKLVQRltDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLR 323
Cdd:pfam02463  328 KELKKEKEEIEELEKELKELEI--KREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  324 QAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGE 403
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  404 LKVAQGKALQEnltllaqtlsnrerEVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLE 483
Cdd:pfam02463  486 LELLLSRQKLE--------------ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  484 HLPMAVQEREQKLSVQRdqiRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHR-KV 562
Cdd:pfam02463  552 EVSATADEVEERQKLVR---ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVeGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  563 EGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQL 642
Cdd:pfam02463  629 LKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  643 TQDLERKGQELVLQKERIQVL------EDQRTLQTKILEEDLEQIKHSL-RERGQELASQWQLMQERAEDGKSPSKaqrg 715
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEaqdkinEELKLLKQKIDEEEEEEEKSRLkKEEKEEEKSELSLKEKELAEEREKTE---- 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  716 sLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ 795
Cdd:pfam02463  785 -KLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  796 GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQV 875
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKK---ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  876 RALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEA 951
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
569-1103 1.29e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  569 ITELEGQRELQRVALTHLTLDL---EERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 645
Cdd:PRK02224   222 IERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  646 LERKGQELVLQKERIQVLEDQRT-LQTKILEEDLEQIKH-----SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEH 719
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEeLRDRLEECRVAAQAHneeaeSLREDADDLEERAEELREEAAELESELEEAREAVED 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  720 LKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQ-L 798
Cdd:PRK02224   382 RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQpV 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  799 EEAQRA--LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAaleqahvtLKERQGELEEHRGQVQRLQEELIVEGRQVR 876
Cdd:PRK02224   462 EGSPHVetIEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  877 ALEEVLGDLRAESREHEktvlalqqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQysrqqeeaAFGQA 956
Cdd:PRK02224   534 EKRERAEELRERAAELE-----------AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE--------SLERI 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  957 EALQEALSKAQATLQEKEQRLLEQAELSctleastATLQATLDTCQARARQLEEAlrVREGEIQTQALQHQEAMQHLQQe 1036
Cdd:PRK02224   595 RTLLAAIADAEDEIERLREKREALAELN-------DERRERLAEKRERKRELEAE--FDEARIEEAREDKERAEEYLEQ- 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1037 lcqKEEDLRQQDEQRQLLEKAVAqrSQENGIQEKQSLEQEKE--EETRGLLESLK------------------------- 1089
Cdd:PRK02224   665 ---VEEKLDELREERDDLQAEIG--AVENELEELEELRERREalENRVEALEALYdeaeelesmygdlraelrqrnvetl 739

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1958767521 1090 ------------------------ELQLTVAQKEEEIL 1103
Cdd:PRK02224   740 ermlnetfdlvyqndayshieldgEYELTVYQKDGEPL 777
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
226-758 1.36e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  226 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ-EEKSKWEGKQNSL 304
Cdd:COG4913    271 LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERL 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  305 ESELRDLHETMASLQSRLRQAELQkmeaqndrelLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLK 384
Cdd:COG4913    351 ERELEERERRRARLEALLAALGLP----------LPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  385 NEEIESERERAQAlqeqgeLKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKA--------ALELL-- 454
Cdd:COG4913    421 LRELEAEIASLER------RKSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfALTLLvp 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  455 SLDLKKRSREVDLQQEQIqeleqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLL------------ 522
Cdd:COG4913    495 PEHYAAALRWVNRLHLRG------RLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGrrfdyvcvdspe 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  523 DLEQKAQVIeSQRGQIqdlkKQLGTLECLALELEESHRKVEGQ--QKVITELEGQRELQRVALThltlDLEERSQELQTQ 600
Cdd:COG4913    569 ELRRHPRAI-TRAGQV----KGNGTRHEKDDRRRIRSRYVLGFdnRAKLAALEAELAELEEELA----EAEERLEALEAE 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  601 SSQLHELENHSTRLAkELQERDQEVMSQRQQIEELQKQKEQLTQ---DLERKGQELVLQKERIQVLEDQRT-LQTKI--L 674
Cdd:COG4913    640 LDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDeLKGEIgrL 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  675 EEDLEQIkhslrergQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQ-QERIQELQEHMGQLEQQLQ 753
Cdd:COG4913    719 EKELEQA--------EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDALRARLNRAEEELE 790


                   ....*
gi 1958767521  754 GLHRK 758
Cdd:COG4913    791 RAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 279-1129 1.51e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 1.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  279 ELQDLQRQLSQSQE--EKSKWEgkqnsleselrdLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQvehLQAC 356
Cdd:pfam15921   86 QVKDLQRRLNESNElhEKQKFY------------LRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ---LQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  357 VTEARAqasaAGVLEEDLrtarsalkLKNEEIESERERAQALQEQGelkvaqgkALQENLTLLaqtlsnrereVETLQAE 436
Cdd:pfam15921  151 VHELEA----AKCLKEDM--------LEDSNTQIEQLRKMMLSHEG--------VLQEIRSIL----------VDFEEAS 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  437 VQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE-QCRSVLEHLPMAVQER-EQKLSVQRDQIRELENDREAQR 514
Cdd:pfam15921  201 GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIfPVEDQLEALKSESQNKiELLLQQHQDRIEQLISEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  515 TALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLAleleeshrkvegqqkvITELEGQRELQRVALTHLTLDLEERS 594
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ----------------LSDLESTVSQLRSELREAKRMYEDKI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  595 QELQTQssqlheLENHSTRLAKELQERDQevmsQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRT------ 668
Cdd:pfam15921  345 EELEKQ------LVLANSELTEARTERDQ----FSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTgnsiti 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  669 --LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE-DGKSPSKAQRGSL----EHLKLILRDKEKEVECQQERIQEL 741
Cdd:pfam15921  415 dhLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAiQGKNESLEKVSSLtaqlESTKEMLRKVVEELTAKKMTLESS 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  742 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVlQGQLEEAQRALAQRDHELEALRQeqqq 821
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNV-QTECEALKLQMAEKDKVIEILRQ---- 569

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  822 trgQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESrehEKTVLALQQ 901
Cdd:pfam15921  570 ---QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEK---VKLVNAGSE 643

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  902 RCaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFG----QAEALQEALSKAQATLQEKEQRL 977
Cdd:pfam15921  644 RL-RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmQLKSAQSELEQTRNTLKSMEGSD 722

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  978 LEQAELSCTLEASTATLQATLDTCQARARQLEEALrvregeiqTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLEKA 1057
Cdd:pfam15921  723 GHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM--------TNANKEKHFLKEEKNKLSQELSTV--ATEKNKMAGEL 792

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767521 1058 VAQRSQENGIQEKQSleqEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 1129
Cdd:pfam15921  793 EVLRSQERRLKEKVA---NMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKP 861
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
501-1016 1.71e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 1.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  501 DQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ-RELQ 579
Cdd:PRK03918   210 NEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElKELK 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  580 RVALTHLTLdlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKER 659
Cdd:PRK03918   290 EKAEEYIKL--SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  660 IQVLEDQRTLQTKI---------------------LEEDLEQIKHSLRERGQELASQWQLMQE-RAEDGKSPSKAQRGSL 717
Cdd:PRK03918   368 KAKKEELERLKKRLtgltpeklekeleelekakeeIEEEISKITARIGELKKEIKELKKAIEElKKAKGKCPVCGRELTE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  718 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQetatlqqrlqeAKEQGELREQVLQGQ 797
Cdd:PRK03918   448 EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKEL-----------AEQLKELEEKLKKYN 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  798 LEEAQRAlaqrDHELEALRQEQQQTRGQEESMKQKTSALQaALEQAHVTLKERQGELEEHRGQVQRLQEELIVEgrQVRA 877
Cdd:PRK03918   517 LEELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGFE--SVEE 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  878 LEEVLGDLRAESREHEKTVLALQqrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAE-NQYSRQQEEAAFGQA 956
Cdd:PRK03918   590 LEERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKRLEELRKElEELEKKYSEEEYEEL 664

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  957 EALQEALSKAQATLQEKEQRLLEQAElscTLEASTATLQATLDTCQARARQLEEALRVRE 1016
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRRE---EIKKTLEKLKEELEEREKAKKELEKLEKALE 721
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
253-868 2.15e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 2.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  253 DDLRDQVQKLVQRLTDTEaqksQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEA 332
Cdd:PRK03918   144 DESREKVVRQILGLDDYE----NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  333 QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQgELKVAQGKAL 412
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  413 QENLTLLAQTLSNREREVETLQAEVQELEKQREmqkaalellslDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 492
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIK-----------ELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  493 EQKLsVQRDQIRELENDREAQRtaLEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV---- 568
Cdd:PRK03918   368 KAKK-EELERLKKRLTGLTPEK--LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgre 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  569 ITELEGQRELQRvalthLTLDLEERSQELQTQSSQLHELENHSTRLAKELqERDQEVMSQRQQIEELQKQKEQLT----Q 644
Cdd:PRK03918   445 LTEEHRKELLEE-----YTAELKRIEKELKEIEEKERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKkynlE 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  645 DLERKGQELVLQKERIQVLE-DQRTLQTKI-----LEEDLEQIKHSLRERGQELASqwqLMQERAEDGKSPSKAQRGSLE 718
Cdd:PRK03918   519 ELEKKAEEYEKLKEKLIKLKgEIKSLKKELekleeLKKKLAELEKKLDELEEELAE---LLKELEELGFESVEELEERLK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  719 HLK------LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslllthreqetatLQQRLQEA-KEQGELRE 791
Cdd:PRK03918   596 ELEpfyneyLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE--------------LRKELEELeKKYSEEEY 661

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  792 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQgELEEHRGQVQRLQEEL 868
Cdd:PRK03918   662 EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE-RVEELREKVKKYKALL 737
mukB PRK04863
chromosome partition protein MukB;
613-1008 2.30e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 2.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  613 RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERiqvledqrtlqTKILEEDLEQIKHSLrergqel 692
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEA-----------ESDLEQDYQAASDHL------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  693 asqwQLMQERAEDGKSPSKAQrGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLThrEQE 772
Cdd:PRK04863   338 ----NLVQTALRQQEKIERYQ-ADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALD--VQQ 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  773 TATLQ-----QRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAAL------- 840
Cdd:PRK04863   411 TRAIQyqqavQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRkiagevs 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  841 -EQAHVTLKERQGELEEHRGQVQRLQE------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAE 913
Cdd:PRK04863   491 rSEAWDVARELLRRLREQRHLAEQLQQlrmrlsELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQ----LQEELEAR 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  914 ARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEE---AAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEAS 990
Cdd:PRK04863   567 LESLSESVSEARERRMALRQQLEQLQARIQRLAARAPawlAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVE 646

                          410
                   ....*....|....*...
gi 1958767521  991 TATLQATLDTCQARARQL 1008
Cdd:PRK04863   647 RDELAARKQALDEEIERL 664
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 492-832 2.93e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 2.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  492 REQKLSVQRDQIRELEN-DREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGqqkvIT 570
Cdd:pfam17380  279 QHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER----IR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  571 ELEGQRELQRValthltldleeRSQELQTQSSQLHELEnhstRLAKELQERDQEVmsqRQQIEELQKQKeQLTQDLERKG 650
Cdd:pfam17380  355 QEERKRELERI-----------RQEEIAMEISRMRELE----RLQMERQQKNERV---RQELEAARKVK-ILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  651 QELVLQKERIQV-LEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlklilRDKEK 729
Cdd:pfam17380  416 QQQKVEMEQIRAeQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELE----------KEKRD 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  730 EVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRD 809
Cdd:pfam17380  486 RKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEER 565

                          330       340
                   ....*....|....*....|...
gi 1958767521  810 HELEALRQEQQQTRGQEESMKQK 832
Cdd:pfam17380  566 SRLEAMEREREMMRQIVESEKAR 588
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
723-1298 3.14e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 3.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  723 ILRDKEKEVECQQERIQELQEHmgQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGElreqvlqgQLEEAQ 802
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE--------EHEERR 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  803 RALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVL 882
Cdd:PRK02224   251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  883 GDLRAESREHEKTVLALQQRCA---EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAEnqysrqqeeaafgqAEAL 959
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADdleERAEELREEAAELESELEEAREAVEDRREEIEELEEE--------------IEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  960 QEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR---ARQLEEALRVREGEIQTQALQHQEAMQHLQQE 1036
Cdd:PRK02224   397 RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERveeAEALLEAGKCPECGQPVEGSPHVETIEEDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1037 LCQKEEDLRQQDEQRQLLEKAVAQrsqengiqEKQSLEQEKEEETrgLLESLKELQLTVAQKEEEILMLREAQQRQNQEA 1116
Cdd:PRK02224   477 VEELEAELEDLEEEVEEVEERLER--------AEDLVEAEDRIER--LEERREDLEELIAERRETIEEKRERAEELRERA 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1117 SspshrsfpaekpslqllLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMfLQASVLERESEQ 1196
Cdd:PRK02224   547 A-----------------ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRT-LLAAIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1197 QRLQEElvlsRQALEEQQS-RGPHSSSRADQGPKAGQDTEPGEVIEAEpspgvGEKEQLRQRLERLQQAVAELEVDRSKL 1275
Cdd:PRK02224   609 ERLREK----REALAELNDeRRERLAEKRERKRELEAEFDEARIEEAR-----EDKERAEEYLEQVEEKLDELREERDDL 679

                          570       580
                   ....*....|....*....|...
gi 1958767521 1276 QCHNAQLRTTLEQVERERRKLKR 1298
Cdd:PRK02224   680 QAEIGAVENELEELEELRERREA 702
mukB PRK04863
chromosome partition protein MukB;
902-1216 3.50e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.88  E-value: 3.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  902 RCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSrQQEEAAFGQ--------------AEALQEALSKAQ 967
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAEL-NEAESDLEQdyqaasdhlnlvqtALRQQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  968 ATLQEKEQRLLEQAELSCT---------------------LEASTATLQATLDTCQARARQLEEALRVRE---------- 1016
Cdd:PRK04863   355 ADLEELEERLEEQNEVVEEadeqqeenearaeaaeeevdeLKSQLADYQQALDVQQTRAIQYQQAVQALErakqlcglpd 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1017 ----------GEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEE------ 1080
Cdd:PRK04863   435 ltadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQrhlaeq 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1081 TRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPS--------------HRSFPAEKPSLQLLLAQQDLERLQNA 1146
Cdd:PRK04863   515 LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDeleqlqeelearleSLSESVSEARERRMALRQQLEQLQAR 594

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1147 LRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAsVLERESEQQRLQEELVLSRQALEEQQSR 1216
Cdd:PRK04863   595 IQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQ-LLERERELTVERDELAARKQALDEEIER 663
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 6-545 4.57e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 4.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    6 QVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQ 85
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   86 EAQEGQRELGVQVELLRQEVKEKEadfvareaQLLEELEASRIAERQvraSLWAQEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:TIGR02169  431 GIEAKINELEEEKEDKALEIKKQE--------WKLEQLAADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQA 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QPENQAQAQLRSLYSVLQQA----------LGSACERRP---ELRGGGDSVPTPWGSDPDQNGASRLLKR---------- 222
Cdd:TIGR02169  500 RASEERVRGGRAVEEVLKASiqgvhgtvaqLGSVGERYAtaiEVAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflp 579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  223 -------GPLLTALS------------------AEAVALALQK--LHQDLWKAQQARDDLR------------------- 256
Cdd:TIGR02169  580 lnkmrdeRRDLSILSedgvigfavdlvefdpkyEPAFKYVFGDtlVVEDIEAARRLMGKYRmvtlegelfeksgamtggs 659

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  257 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElqkMEAQNDR 336
Cdd:TIGR02169  660 RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE---QEEEKLK 736

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  337 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSAL-----KLKNEEIESERERAQALQEQGELKVAQGKA 411
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALndleaRLSHSRIPEIQAELSKLEEEVSRIEARLRE 816

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  412 LQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVdlqQEQIQELEQCRSVLEHLPMAVQE 491
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL---EELEAALRDLESRLGDLKKERDE 893

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767521  492 REQKLSVQRDQIRELendrEAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 545
Cdd:TIGR02169  894 LEAQLRELERKIEEL----EAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 249-941 4.69e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 4.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  249 QQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQ 328
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  329 KMEAQNDR----ELLQASKEKLSAQVEHLQACVTEAR-AQASAAGVLE--EDLRTARSALKL--KNEEIESERERAQALQ 399
Cdd:TIGR00606  428 ADEIRDEKkglgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRILEldQELRKAERELSKaeKNSLTETLKKEVKSLQ 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  400 -EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSL--DLKKRSREVDLQQEQIQELE 476
Cdd:TIGR00606  508 nEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgYFPNKKQLEDWLHSKSKEIN 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  477 QCRSVLEHLPMAVQEREQklsvQRDQIRELENDREAQRTALEHQLLDL---EQKAQVIESQRGQIQDLKKQLGTLECLAL 553
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQ----NKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAMLAGATA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  554 ELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERsqeLQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIE 633
Cdd:TIGR00606  664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSK---LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIID 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  634 ELQKQKEQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQ 713
Cdd:TIGR00606  741 LKEKEIPELRNKLQKVNRD--IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGS 818

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  714 RG--SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslLLTHREQETATLQQRlQEAKEQGELRE 791
Cdd:TIGR00606  819 DLdrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE---LKSEKLQIGTNLQRR-QQFEEQLVELS 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  792 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEelive 871
Cdd:TIGR00606  895 TEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKD----- 969

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  872 gRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEarTLQDSWLQAQATLAEQEQELEALRAE 941
Cdd:TIGR00606  970 -DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ--KIQERWLQDNLTLRKRENELKEVEEE 1036
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 254-868 5.55e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 5.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  254 DLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElqkmeaq 333
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKE------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  334 NDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQ 413
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  414 ENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDlqqeqiqeleqcrsvlehlpmavqERE 493
Cdd:TIGR04523  232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIK------------------------ELE 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  494 QKLSVQRDQIRELENDREaqrtalehQLLDLEQKAQvIESQRGQIQDLKKQLGTLeclaleleeshrkvegqQKVITELE 573
Cdd:TIGR04523  288 KQLNQLKSEISDLNNQKE--------QDWNKELKSE-LKNQEKKLEEIQNQISQN-----------------NKIISQLN 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  574 GQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL 653
Cdd:TIGR04523  342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  654 VLQKERIQVLEDQRTLQTKILeEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEC 733
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEI-KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  734 QQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEqgELREQVLQGQLEEAQRALAQRDHELE 813
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEIEELKQTQK 578

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767521  814 ALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEEL 868
Cdd:TIGR04523  579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
238-842 5.64e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 5.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  238 LQKLHQDLWKAQQARDDLR------DQVQKLVQRLTDTEAQKSQVhsELQDLQRQLSQSQEEKSKWEGKQNSLESELRDL 311
Cdd:COG4913    237 LERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  312 HETMASLQSRLRQAELQKMEAQNDRellqasKEKLSAQVEHLQAcvtEARAQASAAGVLEEDLRTARSALKLKNEEIESE 391
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDR------LEQLEREIERLER---ELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  392 RERAQALQEQGElkvAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQR----EMQKAALELLSLDLKKRSREVdl 467
Cdd:COG4913    386 RAEAAALLEALE---EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAEL-- 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  468 qqeqiqeleqcRSVLEHLPMAVQEREQKLSVQRdqirELENdreaQRTALehqLLDLEQKAQVIE-------SQRGQIQD 540
Cdd:COG4913    461 -----------PFVGELIEVRPEEERWRGAIER----VLGG----FALTL---LVPPEHYAAALRwvnrlhlRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  541 LKKQLGTLECLALELEESHRKVEGQQKVITElEGQRELQRVALTHLTLDLEERSQELQ--TQSSQLHeleNHSTRLAKEL 618
Cdd:COG4913    519 VRTGLPDPERPRLDPDSLAGKLDFKPHPFRA-WLEAELGRRFDYVCVDSPEELRRHPRaiTRAGQVK---GNGTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  619 QERDQEV----MSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqELAs 694
Cdd:COG4913    595 RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  695 qwQLMQERAEDGKSPSKaqrgsLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthrEQETA 774
Cdd:COG4913    672 --ELEAELERLDASSDD-----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA--------------EEELD 730

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521  775 TLQQRLQEAkeqGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 842
Cdd:COG4913    731 ELQDRLEAA---EDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 240-687 1.15e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 1.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  240 KLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLqrqLSQSQEEKSKWEGKQNSLESELRDLHETMASLQ 319
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL---KDEQNKIKKQLSEKQKELEQNNKKIKELEKQLN 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  320 SRlrQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQ 399
Cdd:TIGR04523  292 QL--KSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  400 EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCR 479
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  480 SVLEhlpMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESH 559
Cdd:TIGR04523  450 SVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  560 RKVEgqqKVITELEGQ-----RELQRVALTHLTLDLEERSQELQTQSSQLHE----LENHSTRLAKELQERDQEVMSQRQ 630
Cdd:TIGR04523  527 EKLE---SEKKEKESKisdleDELNKDDFELKKENLEKEIDEKNKEIEELKQtqksLKKKQEEKQELIDQKEKEKKDLIK 603

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  631 QIEELQKQKEQLTQDLERKGQElvlqKERIQVLEDQRTLQTKILEEDLEQIKHSLRE 687
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 356-580 1.17e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  356 CVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQA 435
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  436 EVQELEKQREMQKAALELLSLDLKKRSR----EVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDRE 511
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  512 AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQ-QKVITELEGQRELQR 580
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEElEALIARLEAEAAAAA 240
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 590-1299 1.48e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 1.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  590 LEERSQELQTQSSQLHELENHSTrLAKELQERDQEVMSQrqQIEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTL 669
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQA-LLKEKREYEGYELLK--EKEALERQKEAIERQLASLEEEL----EKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  670 QTKILEEDLEQIKHSLRERGQELASQwqlMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLE 749
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLR---VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  750 QQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQV--LQGQLEEAQRALAQRDHELEALRQEQQQTRGQE 826
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEvDKEFAETRDELkdYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  827 ESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLAL--QQRCA 904
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeaQARAS 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  905 EQAQEHEAEARTLQDSWLQAQATLAEQeqeleALRAENQYSRQQEEAAFGQAEAL--QEALSKAQATLQEKEQRLLEQAE 982
Cdd:TIGR02169  503 EERVRGGRAVEEVLKASIQGVHGTVAQ-----LGSVGERYATAIEVAAGNRLNNVvvEDDAVAKEAIELLKRRKAGRATF 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  983 LSCTLEASTATLQATLdtcqARARQLEEALRVREGEIQTQALQHQEAMQHLQQElcQKEEDLRQQDEQR------QLLEK 1056
Cdd:TIGR02169  578 LPLNKMRDERRDLSIL----SEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVE--DIEAARRLMGKYRmvtlegELFEK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1057 AVA----QRSQENGIQEKQSLEqEKEEETRGLLESLKELQLTVAQKEEEILMLR-EAQQRQNQEASSPSHRSFPAEKPSL 1131
Cdd:TIGR02169  652 SGAmtggSRAPRGGILFSRSEP-AELQRLRERLEGLKRELSSLQSELRRIENRLdELSQELSDASRKIGEIEKEIEQLEQ 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1132 QLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEI-----AMFLQASVLERESEQQRLQEELVLS 1206
Cdd:TIGR02169  731 EEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAlndleARLSHSRIPEIQAELSKLEEEVSRI 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1207 RQALEEQQSRGPHSSSRADQGPKAGQDTEpGEVIEAEpspgvGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTL 1286
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQ-EQRIDLK-----EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRL 884

                          730
                   ....*....|...
gi 1958767521 1287 EQVERERRKLKRD 1299
Cdd:TIGR02169  885 GDLKKERDELEAQ 897
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 398-1102 1.61e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 1.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  398 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLqqeqiqeleq 477
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKN---------- 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  478 crsvlehlpmavqeREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEE 557
Cdd:TIGR04523  115 --------------DKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  558 SHRKVEGQQKVItelegqrELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQK 637
Cdd:TIGR04523  181 EKLNIQKNIDKI-------KNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  638 QKEQLTQDLERKGQELvlqKERIQVLEDQRTLqTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsL 717
Cdd:TIGR04523  254 QLNQLKDEQNKIKKQL---SEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDW--------------------N 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  718 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQ 797
Cdd:TIGR04523  310 KELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  798 LEEAQRaLAQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 877
Cdd:TIGR04523  383 KQEIKN-LESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  878 LEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAE 957
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  958 ALQEALSKAQATLQEKEQRLleqaelsctleastatlqatldtcqaraRQLEEALRVREGEIQTQALQHQeaMQHLQQEL 1037
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKI----------------------------SDLEDELNKDDFELKKENLEKE--IDEKNKEI 570

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767521 1038 CQKEEDlrqqdeqrqllekavaQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI 1102
Cdd:TIGR04523  571 EELKQT----------------QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
PRK11281 PRK11281
mechanosensitive channel MscK;
774-1096 1.66e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.52  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  774 ATLQQRLQEAKEQGELREQ--VLQGQLEEAQRALAQRD---HELEALRQEQQQTRGQEESMKQKTSALQAALEQ------ 842
Cdd:PRK11281    39 ADVQAQLDALNKQKLLEAEdkLVQQDLEQTLALLDKIDrqkEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEetretl 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  843 AHVTLKERQGELEEHRGQVQRLQEELIVEGRQV--------RA-------------LEEVLGDLRAESREHEKTVLALQQ 901
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLvslqtqpeRAqaalyansqrlqqIRNLLKGGKVGGKALRPSQRVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  902 rcAEQA--------QEHEAEARTLQDSWLQAQ-----ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQ 967
Cdd:PRK11281   199 --AEQAllnaqndlQRKSLEGNTQLQDLLQKQrdyltARIQRLEHQLQLLQEAiNSKRLTLSEKTVQEAQSQDEAARIQA 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  968 ATLQEKE--------QRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEI--------QTQALQHQEAMQ 1031
Cdd:PRK11281   277 NPLVAQEleinlqlsQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLKGSLllsrilyqQQQALPSADLIE 356

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521 1032 HL----------QQELCQKEEDLRQQDEqrqLLEKAVAQRSQENGIQEKQSLEQEKEEEtRGLLESL-KEL--QLTVA 1096
Cdd:PRK11281   357 GLadriadlrleQFEINQQRDALFQPDA---YIDKLEAGHKSEVTDEVRDALLQLLDER-RELLDQLnKQLnnQLNLA 430
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 761-1010 1.86e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 1.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  761 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 840
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  841 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 918
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  919 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 998
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767521  999 DTCQARARQLEE 1010
Cdd:NF012221  1765 AQADAKGAKQDE 1776
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 252-920 2.72e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  252 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELR---------------DLHETMA 316
Cdd:pfam15921  305 QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARterdqfsqesgnlddQLQKLLA 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  317 SLQSRLRQAELQKMEAQN--DREL--------LQASKEKLSAQVEHLQACVTEARAQASaaGVLEEDLrtarSALKLKNE 386
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRlwDRDTgnsitidhLRRELDDRNMEVQRLEALLKAMKSECQ--GQMERQM----AAIQGKNE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  387 EIEsereRAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKqremqkaALELLSLDLKKRSREVD 466
Cdd:pfam15921  459 SLE----KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER-------AIEATNAEITKLRSRVD 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  467 lqqeqiqeleqcrsvlehlpMAVQEReQKLSVQRDQIRELENDREAQRtalehqlLDLEQKAQVIESQRGQIQDLKKQLG 546
Cdd:pfam15921  528 --------------------LKLQEL-QHLKNEGDHLRNVQTECEALK-------LQMAEKDKVIEILRQQIENMTQLVG 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  547 ----TLECLALELEESHRKVEGQQKVITELEGQRELQRVALThltlDLEERSQELQTQSSQLHELENHSTRLAKEL-QER 621
Cdd:pfam15921  580 qhgrTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR----ELEARVSDLELEKVKLVNAGSERLRAVKDIkQER 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  622 DQ---EVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQvledqrtLQTKILEEDLEQIKHSLRERGQELASQWQL 698
Cdd:pfam15921  656 DQllnEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK-------MQLKSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  699 mqerAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGL----HRKVGETSLLLTHR---EQ 771
Cdd:pfam15921  729 ----AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVatekNKMAGELEVLRSQErrlKE 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  772 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALrqeqqQTRGQEESMKQKTSALQ-AALEQAHVTLKER 850
Cdd:pfam15921  805 KVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKEL-----QGPGYTSNSSMKPRLLQpASFTRTHSNVPSS 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  851 QGE---LEEHRGQVQRLQE-------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDS 920
Cdd:pfam15921  880 QSTasfLSHHSRKTNALKEdptrdlkQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSS 959
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 763-1006 3.51e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 3.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  763 SLLLTHREQETATLQQRLQEAKEQGELREQVL---QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAA 839
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELaalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  840 LEQAHVTLKERQGELEEHRGQVQRLQE----ELIVEGRQVRALEEVLGDLRAESREhektvlalQQRCAEQAQEHEAEAR 915
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPA--------RREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  916 TLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQ 995
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243

                          250
                   ....*....|.
gi 1958767521  996 ATLDTCQARAR 1006
Cdd:COG4942    244 PAAGFAALKGK 254
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
573-1058 3.56e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  573 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKG-- 650
Cdd:COG4913    259 ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgd 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  651 --QELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKE 728
Cdd:COG4913    339 rlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  729 KEVECQQERIQELQEHMGQLEQQLQGLhRKVGETSLLLTHREQ-------ETATLQQRLQEAKEqGELREQ-----VLQG 796
Cdd:COG4913    419 RELRELEAEIASLERRKSNIPARLLAL-RDALAEALGLDEAELpfvgeliEVRPEEERWRGAIE-RVLGGFaltllVPPE 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  797 QLEEAQRALAQRD-------HELEALRQEQQQTRGQEES----MKQKTSALQAALEQ-----AHVTLKERQGELEEHR-- 858
Cdd:COG4913    497 HYAAALRWVNRLHlrgrlvyERVRTGLPDPERPRLDPDSlagkLDFKPHPFRAWLEAelgrrFDYVCVDSPEELRRHPra 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  859 ----GQV------------QRLQEELIV---EGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQD 919
Cdd:COG4913    577 itraGQVkgngtrhekddrRRIRSRYVLgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY 656

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  920 SW-----LQAQATLAEQEQELEALRAENqysrqqeeaafGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 994
Cdd:COG4913    657 SWdeidvASAEREIAELEAELERLDASS-----------DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521  995 QATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAV 1058
Cdd:COG4913    726 EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
734-1209 4.63e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 4.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  734 QQERIQELQEHMGQLEQQLQGLHRKVGETSL-LLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHE- 811
Cdd:COG4913    260 LAERYAAARERLAELEYLRAALRLWFAQRRLeLLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDr 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  812 LEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR----ALEEVLGDLRA 887
Cdd:COG4913    340 LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  888 ESREHEKTVLALQQR--------------CAEQAQEHEAEA---------RTLQDSWLQA-------QAT--LAEQEQEL 935
Cdd:COG4913    420 ELRELEAEIASLERRksniparllalrdaLAEALGLDEAELpfvgelievRPEEERWRGAiervlggFALtlLVPPEHYA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  936 EALRAENQYSRQQ----EEAAFGQAEALQEALSKAqaTLQEK------------EQRLLEQAELSC--TLEASTATLQAT 997
Cdd:COG4913    500 AALRWVNRLHLRGrlvyERVRTGLPDPERPRLDPD--SLAGKldfkphpfrawlEAELGRRFDYVCvdSPEELRRHPRAI 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  998 LDTCQAR-----------------------ARQLEEALRVREGEIQTQALQHQEAMQHLQQElcqkeedLRQQDEQRQLL 1054
Cdd:COG4913    578 TRAGQVKgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAE-------LDALQERREAL 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1055 EKAVAQRSQENGIQEKQSLEQEKEEETRGLLES---LKELQLTVAQKEEEILMLREAQQRQNQEASSpshrsfpaekpsl 1131
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELERLDASsddLAALEEQLEELEAELEELEEELDELKGEIGR------------- 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521 1132 QLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQA 1209
Cdd:COG4913    718 LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
711-1116 5.49e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 5.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  711 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEAKEQGELR 790
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  791 EQvLQGQLEEAQRALAQRDHEL-EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELI 869
Cdd:COG4717    159 RE-LEEELEELEAELAELQEELeELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  870 VEgRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 945
Cdd:COG4717    238 AA-ALEERLKEARLLLLIAAALLALLGLGGSLLSLILtiagVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  946 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 1025
Cdd:COG4717    317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELL----REAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1026 HQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 1105
Cdd:COG4717    393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

                          410
                   ....*....|.
gi 1958767521 1106 REAQQRQNQEA 1116
Cdd:COG4717    473 ELLQELEELKA 483
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 387-1071 6.17e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 6.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  387 EIESERERAQALQEQGELKVAQGKALQENLT-LLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREV 465
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEkELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  466 DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 545
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  546 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEV 625
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  626 MSQR---------QQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQW 696
Cdd:TIGR00618  435 LQQRyaelcaaaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  697 QLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER--IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 774
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkqRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  775 TLQQRLQEAKEQGELREQVLQGQLEEAQRALAqrDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEl 854
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPEQD--LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  855 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQE 934
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA----AREDALNQSLKE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  935 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRV 1014
Cdd:TIGR00618  748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521 1015 REGEIQTQALQHQEAMQH-LQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQ 1071
Cdd:TIGR00618  828 QEEEQFLSRLEEKSATLGeITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 687-914 8.37e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 8.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  687 ERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 766
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  767 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVT 846
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521  847 LKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEA 914
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK11281 PRK11281
mechanosensitive channel MscK;
905-1296 8.79e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 8.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  905 EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEaLQEALSKAQATLQEKEQRLLEQAELS 984
Cdd:PRK11281    73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQ-LESRLAQTLDQLQNAQNDLAEYNSQL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  985 CTLEASTATLQATLDTCQARARQLEEALRvregeiqtQALQHQEAMQHLQQELCQKEEDL--RQQDEQRQLLEkavaqrs 1062
Cdd:PRK11281   152 VSLQTQPERAQAALYANSQRLQQIRNLLK--------GGKVGGKALRPSQRVLLQAEQALlnAQNDLQRKSLE------- 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1063 qenGIQEKQSLEQEKEEetrglleslkELQLTVAQKEEEILMLREAQQRQNQEASspshrsfpaEKPSLQLLLAQQDLER 1142
Cdd:PRK11281   217 ---GNTQLQDLLQKQRD----------YLTARIQRLEHQLQLLQEAINSKRLTLS---------EKTVQEAQSQDEAARI 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1143 LQNALRQTEAreiewrekAQGLALS--LAQSKASISSL--QEIAMflqASVLERESEQQR--------LQEELVLSRQAL 1210
Cdd:PRK11281   275 QANPLVAQEL--------EINLQLSqrLLKATEKLNTLtqQNLRV---KNWLDRLTQSERnikeqisvLKGSLLLSRILY 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1211 EEQQSRgphsssradqgPKAGQDTEPGEVIeAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQchNAQLRTTLEQVE 1290
Cdd:PRK11281   344 QQQQAL-----------PSADLIEGLADRI-ADLRLEQFEINQQRDALFQPDAYIDKLEAGHKSEV--TDEVRDALLQLL 409


                   ....*.
gi 1958767521 1291 RERRKL 1296
Cdd:PRK11281   410 DERREL 415
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 627-1110 8.87e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 8.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  627 SQRQQIEELQKQKEQLTQDLERKGQELvlqKERIQVLEDQrtlqTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDG 706
Cdd:TIGR00618  191 SLHGKAELLTLRSQLLTLCTPCMPDTY---HERKQVLEKE----LKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  707 KSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQ 786
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  787 GELREQVLQGQLEeaqraLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQE 866
Cdd:TIGR00618  344 RRLLQTLHSQEIH-----IRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  867 ELIVEGRQVRA-LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 945
Cdd:TIGR00618  419 FRDLQGQLAHAkKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  946 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 1025
Cdd:TIGR00618  499 LQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQC 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1026 HQEA-------MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQK 1098
Cdd:TIGR00618  579 DNRSkedipnlQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE 658

                          490
                   ....*....|..
gi 1958767521 1099 EEEILMLREAQQ 1110
Cdd:TIGR00618  659 RVREHALSIRVL 670
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 586-835 1.09e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  586 LTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLED 665
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  666 QRtlqtKILEEDLEQIKHSLRERgqeLASQWQLMQERAED----GKSPSKAQRgSLEHLKLILRDKEKEVECQQERIQEL 741
Cdd:COG4942     91 EI----AELRAELEAQKEELAEL---LRALYRLGRQPPLAlllsPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  742 QEHMGQLEQQLQGLHRKvgetslllthrEQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQ 821
Cdd:COG4942    163 AALRAELEAERAELEAL-----------LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                          250
                   ....*....|....
gi 1958767521  822 TRGQEESMKQKTSA 835
Cdd:COG4942    232 LEAEAAAAAERTPA 245
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 75-454 1.18e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   75 RELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEAdfvaREAQLLEELEASRIAERQVRASLWAQEaKAAQLQLQLRST 154
Cdd:COG3096    285 ERALELRRELFGARRQLAEEQYRLVEMARELEELSA----RESDLEQDYQAASDHLNLVQTALRQQE-KIERYQEDLEEL 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  155 EAQLE------ALVAEQQPENQAQAQ--------LRSLYSVLQQALGSACERRPELRgggdsvptpwgsdpdqnGASRLL 220
Cdd:COG3096    360 TERLEeqeevvEEAAEQLAEAEARLEaaeeevdsLKSQLADYQQALDVQQTRAIQYQ-----------------QAVQAL 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  221 KRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDqvqkLVQRLTDTEAQKSQVHSELQDLQ---------------R 285
Cdd:COG3096    423 EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLE----LEQKLSVADAARRQFEKAYELVCkiageversqawqtaR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  286 QLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQA-ELQKMEAQ--NDRELLQASKEKLSAQVEHLQACVTEARA 362
Cdd:COG3096    499 ELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeEFCQRIGQqlDAAEELEELLAELEAQLEELEEQAAEAVE 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  363 QASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLtllaQTLSNREREVETLQAEVQelEK 442
Cdd:COG3096    579 QRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAM----QQLLEREREATVERDELA--AR 652

                          410
                   ....*....|..
gi 1958767521  443 QREMQKAALELL 454
Cdd:COG3096    653 KQALESQIERLS 664
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 238-545 1.81e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  238 LQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 317
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  318 LQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNE----EIESERE 393
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlsrSINKIKQ 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  394 RAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQEL-----EKQREMQKAALELLSLD--LKKRS--RE 464
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekkEKESKISDLEDELNKDDfeLKKENleKE 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  465 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQ 544
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   .
gi 1958767521  545 L 545
Cdd:TIGR04523  643 L 643
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 479-868 2.03e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 45.97  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  479 RSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQrGQIQDLKKQLGTLECLALELEES 558
Cdd:pfam10174  136 RKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAE-MQLGHLEVLLDQKEKENIHLREE 214

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  559 -HRKVEGQQ-----KVITELEGQRELQRVALTHLTLDLEERSQELQTQS-----------SQLHELENHSTRLAKELQER 621
Cdd:pfam10174  215 lHRRNQLQPdpaktKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllhtedreeeiKQMEVYKSHSKFMKNKIDQL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  622 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVlEDQRTlqtKILEEDLEQIKHSLRERGQELASQWQLMQE 701
Cdd:pfam10174  295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTA-KEQRA---AILQTEVDALRLRLEEKESFLNKKTKQLQD 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  702 RAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQ 781
Cdd:pfam10174  371 LTEE----KSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALS 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  782 EA-------KEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEL 854
Cdd:pfam10174  447 EKeriierlKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAV 526

                          410
                   ....*....|....
gi 1958767521  855 EEHRGQVQRLQEEL 868
Cdd:pfam10174  527 EQKKEECSKLENQL 540
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
738-1188 2.39e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 45.67  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  738 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ 817
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  818 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVL 897
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  898 ALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRL 977
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAA 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  978 LEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKA 1057
Cdd:COG5278    318 AAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAA 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1058 VAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQ 1137
Cdd:COG5278    398 AAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAAL 477

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767521 1138 QDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAS 1188
Cdd:COG5278    478 AAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASA 528
PRK11281 PRK11281
mechanosensitive channel MscK;
220-449 3.64e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  220 LKRGPLLTALSAEAValalqklhQDLWKAQ---QARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQL-SQSQEEKS 295
Cdd:PRK11281    48 LNKQKLLEAEDKLVQ--------QDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNdEETRETLS 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  296 KWEGKQnsLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASkekLSAQVEHLQACVTEARAQASAAGVLEEDLR 375
Cdd:PRK11281   120 TLSLRQ--LESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAA---LYANSQRLQQIRNLLKGGKVGGKALRPSQR 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  376 TARSA-LKLKNEEIESERERAQA-------LQEQGELKVAQGKALQENLTLLaQTLSNREREVETlQAEVQELEKQREMQ 447
Cdd:PRK11281   195 VLLQAeQALLNAQNDLQRKSLEGntqlqdlLQKQRDYLTARIQRLEHQLQLL-QEAINSKRLTLS-EKTVQEAQSQDEAA 272


                   ..
gi 1958767521  448 KA 449
Cdd:PRK11281   273 RI 274
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
243-538 3.67e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 3.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  243 QDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRL 322
Cdd:COG4372     31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  323 RQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ-ALQEQ 401
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAlDELLK 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  402 GELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSV 481
Cdd:COG4372    191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVE 270

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  482 LEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQI 538
Cdd:COG4372    271 KDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327
46 PHA02562
endonuclease subunit; Provisional
 592-832 3.99e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  592 ERSQELQTQSSQLHELEnhstrlakelqerdQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQT 671
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQ--------------QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDEL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  672 KILEEDLEQIKHSLRERGQELA---SQWQLMQERA----EDGKSPSKAQrgslehlklilrdkekEVECQQERIQELQEH 744
Cdd:PHA02562   244 LNLVMDIEDPSAALNKLNTAAAkikSKIEQFQKVIkmyeKGGVCPTCTQ----------------QISEGPDRITKIKDK 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  745 MGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQEAKEQGELREQVLQG----------QLEEAQRALAQRDHELEA 814
Cdd:PHA02562   308 LKELQHSLEKLDTAIDE----LEEIMDEFNEQSKKLLELKNKISTNKQSLITlvdkakkvkaAIEELQAEFVDNAEELAK 383

                          250
                   ....*....|....*...
gi 1958767521  815 LRQEQQQTRGQEESMKQK 832
Cdd:PHA02562   384 LQDELDKIVKTKSELVKE 401
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 8-354 4.50e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521    8 EDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqkelekekasltlSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEA 87
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASR--------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   88 QEGQRELGVQVELLRQEVKEKEADFVAREAQlLEELEASRIAER--QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQ 165
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEA-LNDLEARLSHSRipEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  166 QPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVptpwgsdpdqngASRLLKRGPLLTALSAEAVALALQ--KLHQ 243
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL------------EEELEELEAALRDLESRLGDLKKErdELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  244 DLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkSKWEGKQNSLESELRDLHETMASLQSRLR 323
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRALEPVNM 975

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1958767521  324 QAELQKMEAQNDRELLQASKEKLSAQVEHLQ 354
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 489-1213 5.01e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 5.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  489 VQEREQKLSVQRDQIRELEndREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV 568
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLA--RQFALCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEH 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  569 -ITELEGQRELQRVAltHLTLDLEERSQELQTQSSQLH----ELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQ-- 641
Cdd:pfam12128  226 wIRDIQAIAGIMKIR--PEFTKLQQEFNTLESAELRLShlhfGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEkr 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  642 --LTQDLERKGQELVLQKERIQVLEDQRTlqtKILEEDLEQIKHSLrERGQELASQWQLMQERAE---------DGKSPS 710
Cdd:pfam12128  304 deLNGELSAADAAVAKDRSELEALEDQHG---AFLDADIETAAADQ-EQLPSWQSELENLEERLKaltgkhqdvTAKYNR 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  711 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthREQETATLQqRLQEAKEQGELR 790
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL-------------REQLEAGKL-EFNEEEYRLKSR 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  791 EQVLQGQLEEAQRA------LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRL 864
Cdd:pfam12128  446 LGELKLRLNQATATpelllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDEL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  865 QEELIVegrQVRALEEVLGDLRAESREHEKTVLALQQRCAEQaqeheaeartlqdswLQAQATLAEQEQELEALRAENQY 944
Cdd:pfam12128  526 ELQLFP---QAGTLLHFLRKEAPDWEQSIGKVISPELLHRTD---------------LDPEVWDGSVGGELNLYGVKLDL 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  945 SRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL 1024
Cdd:pfam12128  588 KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1025 QHQEAMQHLQQelcQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEEETRGLLESLKELQLtvAQKEEEILM 1104
Cdd:pfam12128  668 KKNKALAERKD---SANERLNSLEAQLKQLDKKHQAWLEE--QKEQKREARTEKQAYWQVVEGALDAQL--ALLKAAIAA 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1105 LREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDL-ERLQNALRQTEAREIEWREKAQGLALSLAQSKasiSSLQEIAM 1183
Cdd:pfam12128  741 RRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREiRTLERKIERIAVRRQEVLRYFDWYQETWLQRR---PRLATQLS 817

                          730       740       750
                   ....*....|....*....|....*....|
gi 1958767521 1184 FLQASVLERESEQQRLQEELVLSRQALEEQ 1213
Cdd:pfam12128  818 NIERAISELQQQLARLIADTKLRRAKLEME 847
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 772-1101 5.36e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.34  E-value: 5.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  772 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLK-ER 850
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmER 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  851 QGELEEHRgqvqrlQEELIVEGRQVRalEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeARTLQDSWLQAQATLAE 930
Cdd:pfam17380  347 ERELERIR------QEERKRELERIR--QEEIAMEISRMRELERLQMERQQKNERVRQELEA-ARKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  931 QEQELEALRAEnqysrqQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEE 1010
Cdd:pfam17380  418 QKVEMEQIRAE------QEEARQREVRRLEEERAREMERVRLEEQERQQQVE---------------------RLRQQEE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1011 ALRVREGEIQTQALQHQEAMQH----LQQELCQKEEDLRQQDEQRQLLEKAVAQRsQENGIQEKQSLEQEKEEETRGLLE 1086
Cdd:pfam17380  471 ERKRKKLELEKEKRDRKRAEEQrrkiLEKELEERKQAMIEEERKRKLLEKEMEER-QKAIYEEERRREAEEERRKQQEME 549

                          330
                   ....*....|....*
gi 1958767521 1087 SLKELQLTVAQKEEE 1101
Cdd:pfam17380  550 ERRRIQEQMRKATEE 564
mukB PRK04863
chromosome partition protein MukB;
44-445 5.63e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 5.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   44 ELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrELGVQVELLRQEVKEK--EADFVAREAQLLE 121
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASD---HLNLVQTALRQQEKIEryQADLEELEERLEE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  122 ELEASRIAERQVRASlwaqEAKAAQLQLQLRSTEAQLealvAEQQPENQAQAQLRSLYsvlQQALgSACERRPELRGggd 201
Cdd:PRK04863   367 QNEVVEEADEQQEEN----EARAEAAEEEVDELKSQL----ADYQQALDVQQTRAIQY---QQAV-QALERAKQLCG--- 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  202 svptpwGSDPDQNGASRLLKRgplLTAlSAEAVALALQKLHQDLWKAQQARDDLrDQVQKLVQRLTDtEAQKSQVHSELQ 281
Cdd:PRK04863   432 ------LPDLTADNAEDWLEE---FQA-KEQEATEELLSLEQKLSVAQAAHSQF-EQAYQLVRKIAG-EVSRSEAWDVAR 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  282 DLQRQLSQSQEEKSKWEGKQNSLeSELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEAR 361
Cdd:PRK04863   500 ELLRRLREQRHLAEQLQQLRMRL-SELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEAR 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  362 AQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELE 441
Cdd:PRK04863   579 ERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALD 658


                   ....
gi 1958767521  442 KQRE 445
Cdd:PRK04863   659 EEIE 662
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 579-1306 6.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 6.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  579 QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ------ERDQEVMSQRQQIEELQKQKEQLTQDLERKGQE 652
Cdd:COG3096    290 LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQaasdhlNLVQTALRQQEKIERYQEDLEELTERLEEQEEV 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  653 LVLQKERIQVLEDQRTLQtkilEEDLEQIKHSLRERGQEL------ASQWQLMQERAEDGKSPSKAQRGSLEHLK---LI 723
Cdd:COG3096    370 VEEAAEQLAEAEARLEAA----EEEVDSLKSQLADYQQALdvqqtrAIQYQQAVQALEKARALCGLPDLTPENAEdylAA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  724 LRDKEKEVE----CQQERIQELQEHMGQLEQQLQGLHRKVGETSlllthREQETATLQQRLQEAKEQGEL--REQVLQGQ 797
Cdd:COG3096    446 FRAKEQQATeevlELEQKLSVADAARRQFEKAYELVCKIAGEVE-----RSQAWQTARELLRRYRSQQALaqRLQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  798 LEEAQRALAQRdHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 877
Cdd:COG3096    521 LAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAA 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  878 LEEVLgdlraesrehektvLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAafgQAE 957
Cdd:COG3096    600 RAPAW--------------LAAQDA-LERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES---QIE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  958 ALQEALSKAQATLQEKEQR----LLEQAELSCTLE-----------ASTATLQATLDTCQARARQLE---EALRVREGEI 1019
Cdd:COG3096    662 RLSQPGGAEDPRLLALAERlggvLLSEIYDDVTLEdapyfsalygpARHAIVVPDLSAVKEQLAGLEdcpEDLYLIEGDP 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1020 QTQALQHQEAmQHLQQELCQKEEDL--------------RQQDEQRqlLEKAVAQRSQENGIQEKQSLEQEKEEETRGLL 1085
Cdd:COG3096    742 DSFDDSVFDA-EELEDAVVVKLSDRqwrysrfpevplfgRAAREKR--LEELRAERDELAEQYAKASFDVQKLQRLHQAF 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1086 ESLKELQLTVAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllaqqdlerLQNALRQTEAREIEWREKAqgla 1165
Cdd:COG3096    819 SQFVGGHLAVAFAPDPEAELAALRQRRSE----------------------------LERELAQHRAQEQQLRQQL---- 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1166 lslAQSKASISSLQeiAMFLQASVLERESEQQR---LQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEA 1242
Cdd:COG3096    867 ---DQLKEQLQLLN--KLLPQANLLADETLADRleeLREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQA 941

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767521 1243 EPSPGVGEKEQLRQRLERLQQAVAELE----VDRSKLQCHNA----QLRTTLEQVERERRKLkRDSLRASRA 1306
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFALSEVVQRRPhfsyEDAVGLLGENSdlneKLRARLEQAEEARREA-REQLRQAQA 1012
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 920-1154 7.45e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 7.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  920 SWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEqaelsctLEASTATLQATLD 999
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA-------LEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1000 TCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEE 1079
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQ--AEELRADLAELAA 164

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767521 1080 ETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEARE 1154
Cdd:COG4942    165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 855-1063 7.76e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.83  E-value: 7.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  855 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTL----QDSWLQAQATLAE 930
Cdd:COG3914      1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAageaAAAAAALLLLAAL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  931 QEQELEALRAENQYsrQQEEAAFGQAEALQEALSKAQATL--QEKEQRLLEQAELSCT----LEASTATLQATLDTCQAR 1004
Cdd:COG3914     81 LELAALLLQALGRY--EEALALYRRALALNPDNAEALFNLgnLLLALGRLEEALAALRralaLNPDFAEAYLNLGEALRR 158

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767521 1005 ARQLEEALrvregEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQ 1063
Cdd:COG3914    159 LGRLEEAI-----AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 488-714 8.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 8.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  488 AVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 567
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  568 VITELEGQRELQRVALThltldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLE 647
Cdd:COG4942    111 RALYRLGRQPPLALLLS------PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  648 RKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQR 714
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 423-977 8.41e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 8.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  423 LSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQ 502
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  503 IRELENDREAQRTALEHQLLDLEQKAQVIESQrgqiqdLKKQLGTLECLALELEESHRKVEGQQKVITELEGQREL---- 578
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKN------IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLleke 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  579 -------------QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 645
Cdd:TIGR04523  182 klniqknidkiknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  646 LERKGQELvlqKERIQVLEDQRTlQTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsLEHLKLILR 725
Cdd:TIGR04523  262 QNKIKKQL---SEKQKELEQNNK-KIKELEKQLNQLKSEISDLNNQKEQDW--------------------NKELKSELK 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  726 DKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRaL 805
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKN-L 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  806 AQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDL 885
Cdd:TIGR04523  390 ESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  886 RAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSK 965
Cdd:TIGR04523  453 ELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          570
                   ....*....|..
gi 1958767521  966 AQATLQEKEQRL 977
Cdd:TIGR04523  529 LESEKKEKESKI 540
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 639-941 1.08e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  639 KEQLTQDLER-KGQELVLQKERIQVLE------------DQRTLQTKILEEDLEQIKHSLRErgqelasqwQLMQERAED 705
Cdd:PRK10929    25 EKQITQELEQaKAAKTPAQAEIVEALQsalnwleerkgsLERAKQYQQVIDNFPKLSAELRQ---------QLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  706 GKSPSKAQRGSLEHLKLI----LRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQ 781
Cdd:PRK10929    96 RSVPPNMSTDALEQEILQvssqLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNE----IERRLQTLGTPNTPLA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  782 EAkeqgelreQVLQGQLEEAQRALAQRDHELEAL----RQEqqQTRGQEESMKQKTSALQAALEQAHVTLK-ERQGELEE 856
Cdd:PRK10929   172 QA--------QLTALQAESAALKALVDELELAQLsannRQE--LARLRSELAKKRSQQLDAYLQALRNQLNsQRQREAER 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  857 HRGQVQRLQE------ELIVEgrQVRALEEVLGDLRAESREHEktVLALQQRcaeqaqehEAEARTLQDSwlQAQATLAE 930
Cdd:PRK10929   242 ALESTELLAEqsgdlpKSIVA--QFKINRELSQALNQQAQRMD--LIASQQR--------QAASQTLQVR--QALNTLRE 307

                          330
                   ....*....|....*...
gi 1958767521  931 QEQEL-------EALRAE 941
Cdd:PRK10929   308 QSQWLgvsnalgEALRAQ 325
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 229-1060 1.46e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  229 LSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESEL 308
Cdd:pfam01576  229 AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  309 RDLHETMASlqsrlrQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEI 388
Cdd:pfam01576  309 EDTLDTTAA------QQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQAL 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  389 ESERERAQalqeqgelkvAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQ 468
Cdd:pfam01576  383 ESENAELQ----------AELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  469 QEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESqrgQIQDLKKQLgtl 548
Cdd:pfam01576  453 EGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVER---QLSTLQAQL--- 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  549 eclalelEESHRKVEGQQKVITEL-EGQRELQRvalthltlDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMS 627
Cdd:pfam01576  527 -------SDMKKKLEEDAGTLEALeEGKKRLQR--------ELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDH 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  628 QRQQIEELQKQKEQLTQDL-ERKGQELVLQKERIQVLEDQRTLQTKILeedleqikhslrergqELASQWQLMQERAEDG 706
Cdd:pfam01576  592 QRQLVSNLEKKQKKFDQMLaEEKAISARYAEERDRAEAEAREKETRAL----------------SLARALEEALEAKEEL 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  707 KSPSKAQRGSLEHLKLILRDKEKEVecqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQ 786
Cdd:pfam01576  656 ERTNKQLRAEMEDLVSSKDDVGKNV-------HELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQ 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  787 GELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQGELEEHRGQVQRLQE 866
Cdd:pfam01576  729 FERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKK---LELDLKELEAQIDAANKGREEAVKQLKKLQA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  867 ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 946
Cdd:pfam01576  806 QMKDLQRELEEARASRDEILAQSKESEKKLKNLEAE-LLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEK 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  947 QQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE-LSCTLEASTATLQATLDTCQARARQLEEaLRVREGEIQTQA-L 1024
Cdd:pfam01576  885 RRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEqLTTELAAERSTSQKSESARQQLERQNKE-LKAKLQEMEGTVkS 963

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1958767521 1025 QHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 1060
Cdd:pfam01576  964 KFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRR 999
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
776-1020 1.51e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 1.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  776 LQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ--QTRGQEESMKQKTSALQAALEQAhvtlkerQGE 853
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEA-------RAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  854 LEEHRGQVQRLQEELIVEGRQVRALEE--VLGDLRAEsrehektVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQ 931
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQ-------LAELEAELAELSARYTPNHPDVI----ALRAQIAAL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  932 EQELEALRAENQYSRQQE-EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLdtcqARARQLEE 1010
Cdd:COG3206    304 RAQLQQEAQRILASLEAElEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL----QRLEEARL 379

                          250
                   ....*....|
gi 1958767521 1011 ALRVREGEIQ 1020
Cdd:COG3206    380 AEALTVGNVR 389
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 748-1117 1.58e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.96  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  748 LEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 827
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  828 SMKQKTSALQAALEQAHVTLKE--------------RQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHE 893
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIREleediktltqrvleRETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  894 KTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATL 970
Cdd:pfam07888  192 KEFQELRNSLAQrdtQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  971 QEKEQRLLEQAELSCTLEastatlQATLDTCQARARQLEEalrvREGEIQTQALQHqEAMQHLQQELCQKEEDLRQQDEQ 1050
Cdd:pfam07888  272 AELHQARLQAAQLTLQLA------DASLALREGRARWAQE----RETLQQSAEADK-DRIEKLSAELQRLEERLQEERME 340

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521 1051 RQLLEKAVAQRSQENGIQEKQSlEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEAS 1117
Cdd:pfam07888  341 REKLEVELGREKDCNRVQLSES-RRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 21-842 1.74e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.04  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   21 QRLVKQEIEEKVREAQECSRiQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVEL 100
Cdd:pfam02463  198 QELKLKEQAKKALEYYQLKE-KLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  101 LRQEVKEKEADFVAREAQLLEELEASRIAERQ-VRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLY 179
Cdd:pfam02463  277 EEKEKKLQEEELKLLAKEEEELKSELLKLERRkVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  180 SVLQQALGSACERRPElrgggDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQV 259
Cdd:pfam02463  357 EEEELEKLQEKLEQLE-----EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEI 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  260 QKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKwegKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELL 339
Cdd:pfam02463  432 LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK---KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSG 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  340 QASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLL 419
Cdd:pfam02463  509 LKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLK 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  420 AQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCR---SVLEHLPMAVQEREQKL 496
Cdd:pfam02463  589 LPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLrkgVSLEEGLAEKSEVKASL 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  497 SVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQR 576
Cdd:pfam02463  669 SELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEE 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  577 ELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkgQELVLQ 656
Cdd:pfam02463  749 EEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEE--QLLIEQ 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  657 KERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgSLEHLKLILRDKEKEVECQQE 736
Cdd:pfam02463  827 EEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK----------EEELEEQKLKDELESKEEKEK 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  737 RIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQ-----------ETATLQQRLQEAKEQGELREQVLQGQLEEAQRAL 805
Cdd:pfam02463  897 EEKKELEEESQKLNLLEEKENEIEERIKEEAEILLkyeeepeelllEEADEKEKEENNKEEEEERNKRLLLAKEELGKVN 976

                          810       820       830
                   ....*....|....*....|....*....|....*..
gi 1958767521  806 AQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 842
Cdd:pfam02463  977 LMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIE 1013
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 876-978 1.87e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  876 RALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFgq 955
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAA----ELEEKQQELEAQLEQLQEKAAETSQERKQKR-- 218

                           90       100
                   ....*....|....*....|...
gi 1958767521  956 AEALQEALSKAQatLQEKEQRLL 978
Cdd:PRK11448   219 KEITDQAAKRLE--LSEEETRIL 239
46 PHA02562
endonuclease subunit; Provisional
 255-460 2.17e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  255 LRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSK-----WEGKQNSLESELRDLHETMASLQSRLRQAELQK 329
Cdd:PHA02562   172 NKDKIRELNQQIQTLDMKIDHIQQQI-KTYNKNIEEQRKKNGeniarKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  330 MEAQNDRELLQASKEKLSAQVEHLQ-------------ACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ 396
Cdd:PHA02562   251 EDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcpTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD 330

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521  397 ALQEQgelkVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKK 460
Cdd:PHA02562   331 EFNEQ----SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390
PRK12704 PRK12704
phosphodiesterase; Provisional
 19-174 2.71e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   19 DSQRLVKQEIEEKVREAQ-ECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQ 97
Cdd:PRK12704    46 EAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEK-------E 118

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521   98 VELLRQEVKEKEADFVAREAQLLEELEasRIaerqvrASLWAQEAKAAQLQlQLRStEAQLEALVAEQQPENQAQAQ 174
Cdd:PRK12704   119 LEQKQQELEKKEEELEELIEEQLQELE--RI------SGLTAEEAKEILLE-KVEE-EARHEAAVLIKEIEEEAKEE 185
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
26-161 3.07e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   26 QEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEA----DSVR----QRELVSLRQDIQEAQEGQRELGVQ 97
Cdd:COG4913    288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnGGDRleqlEREIERLERELEERERRRARLEAL 367

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767521   98 VELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEAL 161
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 589-692 3.12e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  589 DLEERSQELQTQSSQLHELENHSTRLAKELQErdqevmsqrqQIEELQKQKEQLTQDLERKGQELV--LQKERIQVLEDQ 666
Cdd:PRK00409   524 SLEELERELEQKAEEAEALLKEAEKLKEELEE----------KKEKLQEEEDKLLEEAEKEAQQAIkeAKKEADEIIKEL 593

                           90       100       110
                   ....*....|....*....|....*....|
gi 1958767521  667 RTLQ----TKILEEDLEQIKHSLRERGQEL 692
Cdd:PRK00409   594 RQLQkggyASVKAHELIEARKRLNKANEKK 623
mukB PRK04863
chromosome partition protein MukB;
726-982 3.20e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  726 DKEKEVECQQERIQELQEHMGQLE--------------QQLQGLHRKVGETSLLlthreqETATLQQRLQEAKEQGELRE 791
Cdd:PRK04863   834 DPEAELRQLNRRRVELERALADHEsqeqqqrsqleqakEGLSALNRLLPRLNLL------ADETLADRVEEIREQLDEAE 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  792 QVLQ---------GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE-QAHVTLKERQGELEEHRGQV 861
Cdd:PRK04863   908 EAKRfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQrRAHFSYEDAAEMLAKNSDLN 987

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  862 QRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQ----EQELEA 937
Cdd:PRK04863   988 EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERararRDELHA 1067

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1958767521  938 LRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 982
Cdd:PRK04863  1068 RLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
757-941 3.81e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  757 RKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSAL 836
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  837 QAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE-QAQEHEAEAR 915
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKElEEQLESLQEE 165

                          170       180
                   ....*....|....*....|....*.
gi 1958767521  916 TLQDSWLQAQATLAEQEQELEALRAE 941
Cdd:COG4372    166 LAALEQELQALSEAEAEQALDELLKE 191
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
65-286 3.89e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 3.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   65 VLQEADSVRQ--RELVSLRQDIQEAQEgqrelgvQVELLRQ--EVKEKEADFVAREAQLLEELEASRIAERQVRASLWaq 140
Cdd:COG4913    223 TFEAADALVEhfDDLERAHEALEDARE-------QIELLEPirELAERYAAARERLAELEYLRAALRLWFAQRRLELL-- 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  141 EAKAAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQALGSACER-RPELRGGGDSVPTpwgSDPDQNGASRL 219
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLD---ALREELDELEAQIRGNGGDRLEQlEREIERLERELEE---RERRRARLEAL 367

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  220 LKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQ 286
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
863-1009 4.34e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 4.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  863 RLQEELIVEGRQVRA------LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQEL- 935
Cdd:COG1566     55 RVTEVLVKEGDRVKKgqvlarLDPTDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELe 134

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  936 --EALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELScTLEASTATLQATLDTCQARARQLE 1009
Cdd:COG1566    135 ryQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQLAQAQAGLREEEELA-AAQAQVAQAEAALAQAELNLARTT 209
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
238-453 4.76e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 4.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  238 LQKLHQDLWKAQQARDDLRDQvqklvQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 317
Cdd:COG3206    184 LPELRKELEEAEAALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  318 LQSRLRQAELQKMEAQNDRELLQASKeklSAQVEHLQacVTEARAQASAagvLEEDLRTARSALKlknEEIESERERAQA 397
Cdd:COG3206    259 LLQSPVIQQLRAQLAELEAELAELSA---RYTPNHPD--VIALRAQIAA---LRAQLQQEAQRIL---ASLEAELEALQA 327

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  398 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEL 453
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEAL 383
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
766-1216 5.01e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 41.05  E-value: 5.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  766 LTHREQETATLQQRLQEAKE--QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQA 843
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSltADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  844 HVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQ 923
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  924 AQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQAtldtcQA 1003
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAA-----AA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1004 RARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRG 1083
Cdd:COG5278    313 AAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEV 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1084 LLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQG 1163
Cdd:COG5278    393 LAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVA 472

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767521 1164 LALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 1216
Cdd:COG5278    473 ALAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAAL 525
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 380-1128 6.13e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.19  E-value: 6.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  380 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVET---LQAEVQELEKQREMQKAAlELLSL 456
Cdd:TIGR00606  170 ALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIrdqITSKEAQLESSREIVKSY-ENELD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  457 DLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQR--------DQIRELENDREAQRTALEHQLLDLEQKA 528
Cdd:TIGR00606  249 PLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdEQLNDLYHNHQRTVREKERELVDCQREL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  529 QVIESQRGQIQDLKKQLgtleclalelEESHRKVEGQQKVITELEGQRELQRVAL-THLTLDLEERSQELQTQSSQLHEL 607
Cdd:TIGR00606  329 EKLNKERRLLNQEKTEL----------LVEQGRLQLQADRHQEHIRARDSLIQSLaTRLELDGFERGPFSERQIKNFHTL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  608 -----ENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErkgqelvlqkeriqvledqrtLQTKILEEDLEQIK 682
Cdd:TIGR00606  399 vierqEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE---------------------LKKEILEKKQEELK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  683 HSLRERGQELASQWQLMQERAEDGKspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGET 762
Cdd:TIGR00606  458 FVIKELQQLEGSSDRILELDQELRK--AERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  763 SLLLTHREQETATLQQRLQEAKEQGELREQV---------------LQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 827
Cdd:TIGR00606  536 QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpnkkqledwlhsKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  828 SMKQKTSALQAAL------EQAHVTLKERQGELEEHRGQVQRLQ----------EELIVEGRQVRALEEVLGDLRAESRE 891
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRAMLAgatavysqfiTQLTDENQSCCPVCQRVFQTEAELQE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  892 HEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKaQATLQ 971
Cdd:TIGR00606  696 FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE-QETLL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  972 EKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL-QHQEAMQHLQQELCQKEEDLRQQDEQ 1050
Cdd:TIGR00606  775 GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVnQEKQEKQHELDTVVSKIELNRKLIQD 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1051 RQLLEKAVAQRSQENG-----IQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFP 1125
Cdd:TIGR00606  855 QQEQIQHLKSKTNELKseklqIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKET 934


                   ...
gi 1958767521 1126 AEK 1128
Cdd:TIGR00606  935 SNK 937
PRK12704 PRK12704
phosphodiesterase; Provisional
 995-1118 6.54e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 6.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  995 QATLDTCQARARQ-LEEALRVREGEIQTQALQHQEAMQHLQQELcqkEEDLRQQDEQRQLLEKAVAQRsqENGIQEKQSL 1073
Cdd:PRK12704    30 EAKIKEAEEEAKRiLEEAKKEAEAIKKEALLEAKEEIHKLRNEF---EKELRERRNELQKLEKRLLQK--EENLDRKLEL 104

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1958767521 1074 EQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASS 1118
Cdd:PRK12704   105 LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG 149
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 792-1023 6.97e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  792 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVE 871
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  872 GRQVRALEEVLG-----------DLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRA 940
Cdd:COG3883     99 GGSVSYLDVLLGsesfsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  941 ENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQ 1020
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ...
gi 1958767521 1021 TQA 1023
Cdd:COG3883    259 AGS 261
PRK09039 PRK09039
peptidoglycan -binding protein;
845-980 7.12e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.33  E-value: 7.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  845 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartlqdswlqA 924
Cdd:PRK09039    46 REISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAA-----------A 114

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  925 QATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQ 980
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRES 170
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 950-1298 7.56e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  950 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1029
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1030 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 1108
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1109 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 1185
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521 1186 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 1265
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767521 1266 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 1298
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
735-971 8.71e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.39  E-value: 8.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  735 QERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEakeqgelreqvLQGQLEEAQRALAQRDHELEA 814
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGLVDL-----SEEAKLLLQQLSE-----------LESQLAEARAELAEAEARLAA 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  815 LRQEQQQTRGQeesmkqktsalqAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 894
Cdd:COG3206    245 LRAQLGSGPDA------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767521  895 TVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQ 971
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
PRK09039 PRK09039
peptidoglycan -binding protein;
241-392 8.85e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 39.95  E-value: 8.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  241 LHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQS 320
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767521  321 RLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDL-RTARSALKLKNEEIESER 392
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLgRRLNVALAQRVQELNRYR 196
PRK12704 PRK12704
phosphodiesterase; Provisional
 571-680 9.37e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 9.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  571 ELEGQRELQRvALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKG 650
Cdd:PRK12704    59 LLEAKEEIHK-LRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELI 137

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1958767521  651 QELVLQKERIQVL--EDQRTLQTKILEEDLEQ 680
Cdd:PRK12704   138 EEQLQELERISGLtaEEAKEILLEKVEEEARH 169
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
26-197 9.60e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 9.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   26 QEIEEKVREAQECSRIQKELEKEKAslTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEV 105
Cdd:COG4913    255 EPIRELAERYAAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  106 KEKEADfvaREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQA 185
Cdd:COG4913    333 RGNGGD---RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEA 406

                          170
                   ....*....|..
gi 1958767521  186 LGSACERRPELR 197
Cdd:COG4913    407 LAEAEAALRDLR 418
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
878-1115 9.63e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 9.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  878 LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAE 957
Cdd:COG4372      4 LGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  958 ALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQalqhQEAMQHLQQEL 1037
Cdd:COG4372     84 ELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAER----EEELKELEEQL 159

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767521 1038 CQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQE 1115
Cdd:COG4372    160 ESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 92-768 9.96e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 40.59  E-value: 9.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521   92 RELGVQVELLRQEVKEKEADFVAREAQLLEELEAS---RIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPE 168
Cdd:pfam12128  230 IQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHfgyKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  169 NQAQ----AQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDpdqngasrllkrgplLTALSAEAVALALQklHQD 244
Cdd:pfam12128  310 LSAAdaavAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSE---------------LENLEERLKALTGK--HQD 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  245 LWKAQQARDDLRDQvqklvQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNS-LESELRDLHETMASLQSRLR 323
Cdd:pfam12128  373 VTAKYNRRRSKIKE-----QNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLKSRLG 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  324 QAELQKMEAQNDRELLQaSKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTAR-SALKLKNEEIESERERAQALQEQG 402
Cdd:pfam12128  448 ELKLRLNQATATPELLL-QLENFDERIERAREEQEAANAEVERLQSELRQARKRRdQASEALRQASRRLEERQSALDELE 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  403 ELKVAQGKALQENLTLLAQTLSNREREV---ETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCR 479
Cdd:pfam12128  527 LQLFPQAGTLLHFLRKEAPDWEQSIGKVispELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  480 SVLEHLPMAVQEREQKLSVQRDQIR----ELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDlkkqlgTLECLALEL 555
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANgeleKASREETFARTALKNARLDLRRLFDEKQSEKDKKNK------ALAERKDSA 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  556 EESHRKVEGQQKVITELEGQ--RELQRVALTHLTLDLEERSQELQTQSSQLHEL--------ENHSTRLAKELQERDQEV 625
Cdd:pfam12128  681 NERLNSLEAQLKQLDKKHQAwlEEQKEQKREARTEKQAYWQVVEGALDAQLALLkaaiaarrSGAKAELKALETWYKRDL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767521  626 MSQ---RQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQwqlmQER 702
Cdd:pfam12128  761 ASLgvdPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARL----IAD 836

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767521  703 AEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTH 768
Cdd:pfam12128  837 TKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKR 902
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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