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Conserved domains on  [gi|1958767517|ref|XP_038962799|]
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centrosome-associated protein CEP250 isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-177 2.45e-25

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 105.51  E-value: 2.45e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  103 EEEQQRCESLVEVNTELRLHMEKADV-----------------------------------FFKGYLRGEHGRLLSVWRE 147
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRanealredlqkltndwerareeleqkesewrkeeeAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767517  148 VVTFRRHFLKMKSATDRDLTELKAEHARLS 177
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1523-2076 1.42e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1523 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1602
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1682
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1762
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1842
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1843 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1922
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1923 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2002
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 2003 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2076
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 420-1001 1.13e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 1.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  420 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 499
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  500 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 579
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  580 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 659
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  660 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 739
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  740 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 816
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  817 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 891
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  892 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 971
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767517  972 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1001
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 809-1509 6.59e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.59e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  809 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 882
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  883 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 962
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  963 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1042
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1043 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1115
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1116 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1150
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1151 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1230
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1231 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1310
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1311 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1390
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1391 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1470
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767517 1471 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1509
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 210-457 3.39e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  210 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 289
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  290 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 369
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  370 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 449
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767517  450 QEAWRLRR 457
Cdd:COG4942    234 AEAAAAAE 241
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1914-2262 7.61e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1914 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1993
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1994 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2072
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2073 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2149
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2150 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2229
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767517 2230 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2262
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-177 2.45e-25

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 105.51  E-value: 2.45e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  103 EEEQQRCESLVEVNTELRLHMEKADV-----------------------------------FFKGYLRGEHGRLLSVWRE 147
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRanealredlqkltndwerareeleqkesewrkeeeAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767517  148 VVTFRRHFLKMKSATDRDLTELKAEHARLS 177
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1523-2076 1.42e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1523 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1602
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1682
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1762
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1842
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1843 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1922
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1923 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2002
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 2003 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2076
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 420-1001 1.13e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 1.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  420 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 499
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  500 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 579
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  580 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 659
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  660 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 739
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  740 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 816
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  817 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 891
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  892 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 971
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767517  972 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1001
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 809-1509 6.59e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.59e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  809 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 882
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  883 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 962
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  963 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1042
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1043 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1115
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1116 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1150
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1151 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1230
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1231 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1310
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1311 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1390
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1391 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1470
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767517 1471 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1509
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1221-2024 1.25e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.25e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1221 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1300
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1301 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 1376
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1377 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1456
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1457 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 1523
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1524 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 1603
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1604 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 1683
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1684 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 1760
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1920
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 1999
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767517 2000 ELCQKEEDLrqqDEQRQLLEKAVAQ 2024
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 795-1409 2.49e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.49e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  795 VARQLAQAEQEGQAALERQKVAHEEEVNRLQekwekERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEE 874
Cdd:COG1196    198 LERQLEPLERQAEKAERYRELKEELKELEAE-----LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  875 RTQADsalyqmqletekervSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQaQLRGAQQELKEAIQQHR 954
Cdd:COG1196    273 RLELE---------------ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE-ELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  955 DDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAD 1034
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1035 SVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQ 1114
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1115 LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRgplltALS 1194
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1195 AEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSKWEGKQNSLESELRD 1274
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1275 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1354
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517 1355 ERERAQALQEQGELKVAQGKALQENLTLLAqtlsnrerEVETLQAEVQELEKQRE 1409
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPP--------DLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1337 2.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  530 EEVAAALARAEQSIVELSSSENSLKAEVAdlraAAVKLGALNEAL-ALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSA 608
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  609 LQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEE 688
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  689 ALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKE 768
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  769 viqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLER 848
Cdd:TIGR02168  418 -----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  849 ERTELEM---KLREQHTETEALRAQREEERTQADS-ALYQMQLETEKERVSLLETLLQ------TQKELADASQQLERLR 918
Cdd:TIGR02168  487 LQARLDSlerLQENLEGFSEGVKALLKNQSGLSGIlGVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  919 QDmKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDsqrlVKQEIEEKVRE 998
Cdd:TIGR02168  567 QN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD----LDNALELAKKL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  999 AQECSRIQKELEKEKASLTLSLVEKEKRLLVLQeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVa 1078
Cdd:TIGR02168  642 RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-----RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1079 reaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRp 1158
Cdd:TIGR02168  716 ---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI- 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1159 elrgggdsvptpwgsdpdQNGASRLLKRGPLLTALSAEAVAL--ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQ 1236
Cdd:TIGR02168  792 ------------------EQLKEELKALREALDELRAELTLLneEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1237 KSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEH 1316
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820
                   ....*....|....*....|.
gi 1958767517 1317 LQACVTEARAQASAAGVLEED 1337
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLE 954
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1220-1785 8.85e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.31  E-value: 8.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1220 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 1299
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1300 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 1379
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1380 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 1459
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1460 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 1539
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1540 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 1619
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1620 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 1699
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1700 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 1779
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767517 1780 RQEQQQ 1785
Cdd:PRK02224   714 YDEAEE 719
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1337-1855 5.03e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 5.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1337 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 1409
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1410 MQKAALE--LLSLDLKKRSREV--DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 1485
Cdd:PRK02224   290 ELEEERDdlLAEAGLDDADAEAveARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1486 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 1565
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1566 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 1631
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1632 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 1705
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1706 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 1784
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1785 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 1855
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 776-1613 6.67e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  776 CLKLELDTERSHAEQERDAvARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEM 855
Cdd:pfam02463  191 DLEELKLQELKLKEQAKKA-LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQ 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  856 KLREQhteTEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGML 935
Cdd:pfam02463  270 VLKEN---KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  936 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1015
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1016 LTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER 1095
Cdd:pfam02463  427 EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1096 QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPElrgggdsvptpWGSDP 1175
Cdd:pfam02463  507 SGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL-----------TELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1176 DQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ 1255
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1256 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE 1335
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1336 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLlAQTLSNREREVETLQAEVQELEKQREMQKAAL 1415
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1416 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1495
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1496 ESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK-----VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHE 1570
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILlkyeeEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767517 1571 LENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1613
Cdd:pfam02463  975 VNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 363-1008 1.18e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  363 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARgELQ 442
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-EAK 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  443 QQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERErlqetlvGLEAKQSESLSELIALREALESSRLAG 522
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE-------AAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  523 ELLKQEQEEVAAALARAEQSIVELSSSENSLKAEvaDLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAA 602
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE--EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  603 EQLRSALQVDLAEAERSREAlwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQD 682
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKA--EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  683 AERQEEAlaRAGQEKEALVRERAALEVRLQAVERdrqdlAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT 762
Cdd:PTZ00121  1551 LKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  763 IIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE----EEVNRLQE---KWEKERALL 835
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaEEDEKKAAealKKEAEEAKK 1703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  836 QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSA---------LYQMQLETEKERVSLLETLLQTQKE 906
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdeeekkkIAHLKKEEEKKAEEIRKEKEAVIEE 1783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  907 LADASQQLERLRQDMKVQKLKE---------QETTGMLQAQLRGAQQELKEAI---QQHRDDLAAFQKDKIDlQKQVEDL 974
Cdd:PTZ00121  1784 ELDEEDEKRRMEVDKKIKDIFDnfaniieggKEGNLVINDSKEMEDSAIKEVAdskNMQLEEADAFEKHKFN-KNNENGE 1862

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1958767517  975 TSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1008
Cdd:PTZ00121  1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1447-2261 3.74e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 3.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1447 EHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtleclaleLEESHRKV 1526
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1527 EGQ-QKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHEL--------------------------ENHSTRLA 1579
Cdd:pfam15921  144 RNQlQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeeasgkkiyehdsmstmhfRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1580 KELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQ-KERIQVLEDQRTLQTKILEEDleqiKHSLRERGQELAS 1658
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEK----ASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1659 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1738
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1739 TLQQRLQEAKEQGELREQVLQGQLEEAQRaLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlkERQGEL 1818
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS------ECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1819 EEHRGQVQRLQEELivegrqvraleEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQE 1898
Cdd:pfam15921  447 ERQMAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1899 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQlEEALRV 1978
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT-AGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1979 REGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEkaVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLT 2058
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2059 VAQKEEEILMLREAQQRQNQEASSPSHrsfpaeKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKAS 2138
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTN------KLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ 742

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2139 ISSLQEIAMFLQASVLERESEQQRLQEElvlsRQALEEQQSrgphsssradqgpkagqdtepgeVIEAEPSPGVGEKEQL 2218
Cdd:pfam15921  743 IDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELS-----------------------TVATEKNKMAGELEVL 795

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767517 2219 RQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLK 2261
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 751-1068 4.45e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 4.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  751 VTKSQLEVQIQTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVA----RQLAQAEQEGQAALERQKVAHEEEVNRLQ 825
Cdd:pfam17380  265 MTENEFLNQLLHIVQHQKAVSERQQQEKFEkMEQERLRQEKEEKAREverrRKLEEAEKARQAEMDRQAAIYAEQERMAM 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 EKWEKERALLQQKLDKTLETLERERTELEM-KLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslleTLLQTQ 904
Cdd:pfam17380  345 ERERELERIRQEERKRELERIRQEEIAMEIsRMRELERLQMERQQKNERVRQELEAARKVKILEEERQR-----KIQQQK 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  905 KELADASQQLERLRQDmKVQKLKEQETTGMlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDltsQLVTHNDS 984
Cdd:pfam17380  420 VEMEQIRAEQEEARQR-EVRRLEEERAREM--ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD---RKRAEEQR 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  985 QRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVSLRQDIQEAQEGQRELGVQVEL 1064
Cdd:pfam17380  494 RKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER---RKQQEMEERRRIQEQMRKATEERSRLEA 570


                   ....
gi 1958767517 1065 LRQE 1068
Cdd:pfam17380  571 MERE 574
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1725-1974 3.31e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 3.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1725 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 1804
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1805 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 1882
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1883 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 1962
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767517 1963 DTCQARARQLEE 1974
Cdd:NF012221  1765 AQADAKGAKQDE 1776
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 210-457 3.39e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  210 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 289
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  290 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 369
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  370 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 449
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767517  450 QEAWRLRR 457
Cdd:COG4942    234 AEAAAAAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 205-561 1.27e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  205 SEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNH 284
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  285 AELMEHEASLSRNAqEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQdpnkaLTLVHSVLTRR 364
Cdd:TIGR02169  751 QEIENVKSELKELE-ARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR-----LREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  365 QQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQ 444
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  445 LEVLEQEAWRLRrvnvELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSEsLSELIALREALESSRLAGEl 524
Cdd:TIGR02169  905 IEELEAQIEKKR----KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAE-LQRVEEEIRALEPVNMLAI- 978

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1958767517  525 lkQEQEEVAAALAraeqsivELSSSENSLKAEVADLR 561
Cdd:TIGR02169  979 --QEYEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1914-2262 7.61e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1914 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1993
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1994 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2072
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2073 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2149
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2150 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2229
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767517 2230 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2262
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-177 2.45e-25

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 105.51  E-value: 2.45e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  103 EEEQQRCESLVEVNTELRLHMEKADV-----------------------------------FFKGYLRGEHGRLLSVWRE 147
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRanealredlqkltndwerareeleqkesewrkeeeAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767517  148 VVTFRRHFLKMKSATDRDLTELKAEHARLS 177
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1523-2076 1.42e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1523 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1602
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1682
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1762
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1842
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1843 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1922
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1923 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2002
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 2003 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2076
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 420-1001 1.13e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 1.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  420 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 499
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  500 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 579
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  580 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 659
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  660 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 739
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  740 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 816
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  817 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 891
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  892 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 971
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767517  972 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1001
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1691-2233 1.54e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.54e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1691 KEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAkeqgELREQVLQGQLEEAQRALA 1770
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1771 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLR 1850
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1851 AESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKA 1930
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEA----LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1931 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQkeEDLRQ 2010
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA--VLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2011 QDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE---EILMLREAQQRQNQEASSPSHRS 2087
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAalaAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2088 FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEEL 2167
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2168 VLSRQALEEQQSRGPHSSSRADQG----------------------PKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERL 2225
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERleeeleeealeeqleaereellEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*...
gi 1958767517 2226 QQAVAELE 2233
Cdd:COG1196    773 EREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 402-919 3.08e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 3.08e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  402 RLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELH 481
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  482 LAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLR 561
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  562 AAAVK-------LGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQL 634
Cdd:COG1196    393 RAAAElaaqleeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  635 RKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAV 714
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  715 ERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTE---------- 784
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgrtlvaarl 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  785 ----RSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQ 860
Cdd:COG1196    633 eaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517  861 HTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 919
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 809-1509 6.59e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.59e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  809 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 882
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  883 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 962
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  963 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1042
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1043 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1115
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1116 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1150
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1151 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1230
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1231 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1310
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1311 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1390
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1391 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1470
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767517 1471 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1509
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1221-2024 1.25e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.25e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1221 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1300
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1301 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 1376
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1377 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1456
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1457 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 1523
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1524 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 1603
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1604 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 1683
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1684 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 1760
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1920
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 1999
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767517 2000 ELCQKEEDLrqqDEQRQLLEKAVAQ 2024
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1699-2277 1.71e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 1.71e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1699 QERIQELQEHMGQLEQQLQGLHRkvgetslllthrEQETATLQQRLQEAKEQGELREQVL-----QGQLEEAQRALAQRD 1773
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER------------QAEKAERYRELKEELKELEAELLLLklrelEAELEELEAELEELE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1774 HELEALRQEQQQTRGQEESMKQKTSALQAALEqahvtlkERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAES 1853
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEELELELE-------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1854 REHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQAT 1933
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELE----EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1934 LQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEEALRVREGEIQTQALQHQEAMQHLQQELcqkEEDLRQQDE 2013
Cdd:COG1196    402 LEELEEAEEALLE---------------------RLERLEEELEELEEALAELEEEEEEEEEALEEAA---EEEAELEEE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2014 QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 2093
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2094 SLQLLLAQQDLERLQNALRQTEAREIEW-----REKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELV 2168
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVAAAAIEYlkaakAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2169 LSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRT 2248
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          570       580
                   ....*....|....*....|....*....
gi 1958767517 2249 TLEQVERERRKLKRDSLRASRAGSLEARE 2277
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEAL 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 795-1409 2.49e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.49e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  795 VARQLAQAEQEGQAALERQKVAHEEEVNRLQekwekERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEE 874
Cdd:COG1196    198 LERQLEPLERQAEKAERYRELKEELKELEAE-----LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  875 RTQADsalyqmqletekervSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQaQLRGAQQELKEAIQQHR 954
Cdd:COG1196    273 RLELE---------------ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE-ELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  955 DDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAD 1034
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1035 SVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQ 1114
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1115 LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRgplltALS 1194
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1195 AEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSKWEGKQNSLESELRD 1274
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1275 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1354
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517 1355 ERERAQALQEQGELKVAQGKALQENLTLLAqtlsnrerEVETLQAEVQELEKQRE 1409
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPP--------DLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1211-1946 2.63e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 2.63e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1211 KAQQARDDLRD-QVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQA 1289
Cdd:TIGR02168  214 RYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1290 -------ELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----R 1358
Cdd:TIGR02168  294 aneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1359 AQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQE 1438
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1439 LEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL--- 1505
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisv 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1506 KKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEeRSQELQTQSSQLHELENHSTRLAKELQER 1585
Cdd:TIGR02168  532 DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSI-KGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1586 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELvlQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQE 1665
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLDNALELAKKLR--PGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1666 RAEDgkspskaqrgslehlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL- 1744
Cdd:TIGR02168  689 LEEK------------------IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIa 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1745 QEAKEQGELREQ--VLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtLKERQGELEEhr 1822
Cdd:TIGR02168  751 QLSKELTELEAEieELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAANLRE-- 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1823 gQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEAL 1902
Cdd:TIGR02168  825 -RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA----LLNERASLEEALALLRSELEEL 899

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958767517 1903 RAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 1946
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-917 4.19e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 4.19e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  351 NKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKE 430
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  431 RELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIA 510
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  511 LREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVAlnqqllqleq 590
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE---------- 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  591 enqsmcsRVEAAEQLRSALQVDLAEAERSREALWEEKtHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQE 670
Cdd:COG1196    468 -------LLEEAALLEAALAELLEELAEAAARLLLLL-EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  671 AATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQ 750
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  751 VTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEK 830
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  831 ERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEErtqadsaLYQMQLETEKERVSLLETLLQTQKELADA 910
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE-------EEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1958767517  911 SQQLERL 917
Cdd:COG1196    773 EREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1190-1793 7.02e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 7.02e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1190 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLE 1269
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1270 SELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKN 1349
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1350 EEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsrev 1429
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE------------- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1430 dlqqeqiqeleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRgqiqDLKKQL 1509
Cdd:COG1196    446 ----------------------EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL----LLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1510 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQ-LHELENHSTRLAKELQERDQE 1588
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1589 VMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 1668
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1669 DGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLqglhRKVGETSLLLTHREQETATLQQRLQEAK 1748
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----RELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958767517 1749 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESM 1793
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 761-1317 3.20e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 3.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  761 QTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVARQLAQAE---QEGQAALERQKVAHEEEVNRLQEKWEKERALLQ 836
Cdd:COG1196    216 RELKEELKELEAELLLLKLReLEAELEELEAELEELEAELEELEaelAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  837 QkldktLETLERERTELEmkLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslLETLLQTQKELADASQQLER 916
Cdd:COG1196    296 E-----LARLEQDIARLE--ERRRELEERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  917 LRQDMKVQKLKEQETtgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKV 996
Cdd:COG1196    366 ALLEAEAELAEAEEE----LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  997 REAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSL--RQDIQEAQEGQRELGVQVELLRQEVKEK-- 1072
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAaaRLLLLLEAEADYEGFLEGVKAALLLAGLrg 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1073 -------EADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSV 1145
Cdd:COG1196    522 lagavavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1146 LQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAV------ALALQKLHQDLWKAQQARDDL 1219
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEggsaggSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1220 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQND 1299
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*...
gi 1958767517 1300 RELLQASKEKLSAQVEHL 1317
Cdd:COG1196    762 LEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1464-2024 4.65e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 4.65e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1464 RDQIRELENDREAQRTALEHQ----LLDLEQKAQVIESQRGQIQDLKKQLGTLEclaleleeshRKVEGQQKVITELEGQ 1539
Cdd:COG1196    199 ERQLEPLERQAEKAERYRELKeelkELEAELLLLKLRELEAELEELEAELEELE----------AELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1540 RELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVL 1619
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1620 QKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEdgkspskaQRGSLEHLKLILRDKEKEVECQQ 1699
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--------LAAQLEELEEAEEALLERLERLE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1700 ERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 1779
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1780 RQEQQQTRGQEESMKQK--------------------------------------TSALQAALEQAHVTLKERQGELEEH 1821
Cdd:COG1196    501 ADYEGFLEGVKAALLLAglrglagavavligveaayeaaleaalaaalqnivvedDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1822 RGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQEL-- 1899
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAgg 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1900 ------EALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSctleastatlqatLDTCQARARQLE 1973
Cdd:COG1196    661 sltggsRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE-------------RLEEELEEEALE 727

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1974 EALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 2024
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 836-1640 1.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  836 QQKLDKTLETLER---ERTELEM---KLREQHTETEALRAQREEERtQADSALYQMQLEtekervSLLETLLQTQKELAD 909
Cdd:TIGR02168  178 ERKLERTRENLDRledILNELERqlkSLERQAEKAERYKELKAELR-ELELALLVLRLE------ELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  910 ASQQLERLRQDMKVqKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVK 989
Cdd:TIGR02168  251 AEEELEELTAELQE-LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  990 QEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEV 1069
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1070 KEKEADFVAREAQLLEELEASRIAERQ-VRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQ 1148
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1149 ALGSACERRPELRGGGDSVPTPWgsdpdQNGASRLLKRGPLLTALSAE-----AVALALQKLHQDLW--KAQQARDDLRD 1221
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALL-----KNQSGLSGILGVLSELISVDegyeaAIEAALGGRLQAVVveNLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1222 QVQKLVQRLTDTEAqKSQVHSELQDLQRQLSQSQEEkskWEGKQNSLESELRDLHETMASLQSRLRQAELQKmEAQNDRE 1301
Cdd:TIGR02168  565 LKQNELGRVTFLPL-DSIKGTEIQGNDREILKNIEG---FLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD-NALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1302 LLQASKEKLSAQVEHLQACVTEARAQASAAGV----------LEEDLRTARSALKLKNEEIESERERAQALQEQGELKVA 1371
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSilerrreieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1372 QGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKrsrevdlqqeQIQELEQCRSVLEHLPM 1451
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE----------AEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1452 AVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtleclaleleeshrkvEGQQK 1531
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI-----------------EELSE 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1532 VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLtqdle 1611
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL----- 927

                          810       820
                   ....*....|....*....|....*....
gi 1958767517 1612 rkgqelVLQKERIQVLEDQrtLQTKILEE 1640
Cdd:TIGR02168  928 ------ELRLEGLEVRIDN--LQERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1228-2043 1.71e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.71e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1228 QRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEgKQNSLESELRDLHETMA-----SLQSRLRQAELQKMEAQNDREL 1302
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLvlrleELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1303 LQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTL 1382
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSE----------LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1383 LAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSV 1462
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELE----------ELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1463 QRDQIRELENdrEAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRkvegqqkvitELEGQREL 1542
Cdd:TIGR02168  398 LNNEIERLEA--RLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE----------RLEEALEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1543 QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLE-RKGQELVL-- 1619
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIEAALgg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1620 ------------QKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLI 1687
Cdd:TIGR02168  546 rlqavvvenlnaAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1688 LRDKEKEVECQQERIQELQEHMGQLEQQLQG----LHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQG--- 1760
Cdd:TIGR02168  626 LVVDDLDNALELAKKLRPGYRIVTLDGDLVRpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAElrk 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1920
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELR----AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRvregEIQTQALQHQEAMQHLQQE 2000
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLELRLEGLEVR 937

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1958767517 2001 LCQKEEDLR--QQDEQRQLLEKAVAQRSQENGIQEKQ-SLEQEKEE 2043
Cdd:TIGR02168  938 IDNLQERLSeeYSLTLEEAEALENKIEDDEEEARRRLkRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1337 2.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  530 EEVAAALARAEQSIVELSSSENSLKAEVAdlraAAVKLGALNEAL-ALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSA 608
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  609 LQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEE 688
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  689 ALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKE 768
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  769 viqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLER 848
Cdd:TIGR02168  418 -----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  849 ERTELEM---KLREQHTETEALRAQREEERTQADS-ALYQMQLETEKERVSLLETLLQ------TQKELADASQQLERLR 918
Cdd:TIGR02168  487 LQARLDSlerLQENLEGFSEGVKALLKNQSGLSGIlGVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  919 QDmKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDsqrlVKQEIEEKVRE 998
Cdd:TIGR02168  567 QN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD----LDNALELAKKL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  999 AQECSRIQKELEKEKASLTLSLVEKEKRLLVLQeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVa 1078
Cdd:TIGR02168  642 RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-----RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1079 reaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRp 1158
Cdd:TIGR02168  716 ---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI- 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1159 elrgggdsvptpwgsdpdQNGASRLLKRGPLLTALSAEAVAL--ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQ 1236
Cdd:TIGR02168  792 ------------------EQLKEELKALREALDELRAELTLLneEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1237 KSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEH 1316
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820
                   ....*....|....*....|.
gi 1958767517 1317 LQACVTEARAQASAAGVLEED 1337
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLE 954
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 499-1125 2.45e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.23  E-value: 2.45e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  499 AKQSESLSELIALREALEssRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDK 578
Cdd:COG1196    206 ERQAEKAERYRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  579 VALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEEL 658
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  659 KEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGN 738
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  739 LFEAQQQNSVIQVTKSQLEVQIQtiiqakeviqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE 818
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLA------------------ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  819 EEVNRLQEKWEKERALLQQKLDKTLETLERERTELEmklreqhTETEALRAQREEERTQADSALYQMQLETEKERVSLLE 898
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE-------AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  899 TLLQTQKELADAsqqlerlrqdmkvqklkeqettgmlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQL 978
Cdd:COG1196    579 LDKIRARAALAA--------------------------ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  979 VTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQREL 1058
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1059 GVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEAL 1125
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1533-2267 2.63e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.63e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1533 ITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKE-------Q 1605
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrerlaN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1606 LTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKhSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLK 1685
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1686 LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETatlqqrLQEAKEQGELREQVLQGQLEEA 1765
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE------LEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1766 QRALAQRDHELEALRQEQQQTRGQEESMKQktsaLQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEV 1845
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLER----LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1846 LGdlraesrEHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQeqeleaLRAENQYSRQQEEAAFGQAEALQE 1925
Cdd:TIGR02168  543 LG-------GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE------IQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1926 ALSKAQATLQEKEQRLLeqaelsctleastatLQATLDTCQARARQLEEALRV---------REGEIQTQALQHQEAMQH 1996
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVL---------------VVDDLDNALELAKKLRPGYRIvtldgdlvrPGGVITGGSAKTNSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1997 LQQELCQKEEDLRQQDEQRQLLEKAVA-----QRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLRE 2071
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAelrkeLEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2072 AQQRQNQEASSpshrsfpaekpslqlllAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQA 2151
Cdd:TIGR02168  755 ELTELEAEIEE-----------------LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2152 SVLERESEQQRLQEELVLSRQALEEQQSRgphsssradqgpkAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAE 2231
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQ-------------IEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1958767517 2232 LEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRA 2267
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEEL 920
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1201-1936 1.71e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 1.71e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1201 ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMA 1280
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1281 SLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvleedlrtarsalklkneEIESERERAQ 1360
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL-------------------EDRRERLQQE 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1361 ALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE 1440
Cdd:TIGR02168  423 IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1441 QCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQviESQRGQIQDLKKQLGTLECLALELE 1520
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL--NAAKKAIAFLKQNELGRVTFLPLDS 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1521 ESHRKVEGQQKVIteLEGQRELQRVALTHLTLDLEER------------SQELQTQSSQLHELENHST------------ 1576
Cdd:TIGR02168  581 IKGTEIQGNDREI--LKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvVDDLDNALELAKKLRPGYRivtldgdlvrpg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1577 -RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL-VLQKERIQVLEDQRTLQTKILEED-----LEQIKHSL 1649
Cdd:TIGR02168  659 gVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALaELRKELEELEEELEQLRKELEELSrqisaLRKDLARL 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1650 RERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLL 1729
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1730 LTHREQETATLQQRLQEAKEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHV 1809
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1810 TLKERQGELEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSW 1885
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRREL-------EELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDE 967

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767517 1886 LQAQATLAEQEQELEA-----LRAENQYSRQQEEAAF--GQAEALQEALSKAQATLQE 1936
Cdd:TIGR02168  968 EEARRRLKRLENKIKElgpvnLAAIEEYEELKERYDFltAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1275-2076 2.25e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 2.25e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1275 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1354
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1355 ERERAQALQEQgelkvaqgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQE 1434
Cdd:TIGR02168  275 EVSELEEEIEE----------LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1435 QIQELEQCrsvLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALehqlLDLEQKAQVIESQRGQIQDLKKQLGTLEC 1514
Cdd:TIGR02168  345 KLEELKEE---LESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1515 LALELEESHRKvEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMS--- 1591
Cdd:TIGR02168  418 RLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSler 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1592 QRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIkhsLRERGQELASQWQLMQERAEDGK 1671
Cdd:TIGR02168  497 LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAV---VVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1672 SPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgeTSLLLTHREQETATLQQRLQEAKE-- 1749
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYri 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1750 ---QGEL--REQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQ 1824
Cdd:TIGR02168  648 vtlDGDLvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1825 VQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEA 1901
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1902 LRAEnqYSRQQEEAAfgqaeALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREG 1981
Cdd:TIGR02168  808 LRAE--LTLLNEEAA-----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1982 EIQtqalQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENG--IQEKQSLEQEKEEETRGLLESLKELQLTV 2059
Cdd:TIGR02168  881 ERA----SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAqlELRLEGLEVRIDNLQERLSEEYSLTLEEA 956

                          810
                   ....*....|....*..
gi 1958767517 2060 AQKEEEILMLREAQQRQ 2076
Cdd:TIGR02168  957 EALENKIEDDEEEARRR 973
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 397-1142 2.97e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.97e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  397 KALRERLQKLtgERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQ 476
Cdd:TIGR02168  216 KELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  477 QEELH-------LAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSS 549
Cdd:TIGR02168  294 ANEISrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  550 ENSLKAEVADLRAAAVKLgaLNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTH 629
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQL--ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  630 LETQLRKAEETGAELQAELRGAREEKEELKEKLNEAhHQQEAATAQLQQLHQDAERQEEALARAGQEKEAL--------- 700
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQL-QARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlselis 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  701 VRER------AALEVRLQAVERDRQDLAEQvlglrsakeqlegnLFEAQQQNSVIQVTKSQLEVQIQTIIQAK--EVIQG 772
Cdd:TIGR02168  531 VDEGyeaaieAALGGRLQAVVVENLNAAKK--------------AIAFLKQNELGRVTFLPLDSIKGTEIQGNdrEILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  773 EVKCLKLELDTErSHAEQERDAVARQLAQAE--QEGQAALERQKVAHEEEVNRLQE-----------KWEKERALLQQKL 839
Cdd:TIGR02168  597 IEGFLGVAKDLV-KFDPKLRKALSYLLGGVLvvDDLDNALELAKKLRPGYRIVTLDgdlvrpggvitGGSAKTNSSILER 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  840 DKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQlETEKERVSLLETLLQTQKELADASQQLERLRQ 919
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  920 DMKVQKLKEQETTGMLqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREA 999
Cdd:TIGR02168  755 ELTELEAEIEELEERL-EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1000 QECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAr 1079
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE- 912

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 1080 eaqLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRStEAQLEALVAEQQP------ENQAQAQLRSL 1142
Cdd:TIGR02168  913 ---LRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALEnkieddEEEARRRLKRL 977
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1268-1832 6.71e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 6.71e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1268 LESELRDLHETMASLQSRLRQAELQKMEAQndRELLQASKEKLSAQVEHLQACVTEARAQASAAG----VLEEDLRTARS 1343
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELEELEleleEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1344 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLK 1423
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1424 KRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQ 1503
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1504 DLKKQLGTLECLALELEESHRKVEGQQkvitelegQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ 1583
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAEL--------LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1584 ERDQEVMSQRQQIEE-----LQKQKEQLTQDLERKGQELVLQKE-RIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELA 1657
Cdd:COG1196    528 VLIGVEAAYEAALEAalaaaLQNIVVEDDEVAAAAIEYLKAAKAgRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1658 SQWQLMQERAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLthREQET 1737
Cdd:COG1196    608 LREADARYYVLG----DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE--AEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1738 ATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGE 1817
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*
gi 1958767517 1818 LEEHRGQVQRLQEEL 1832
Cdd:COG1196    762 LEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 888-1658 1.39e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 1.39e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  888 ETEKERVSLLETLLQTQKELADASQQLERL-RQDMKVQKLKEqettgmLQAQLRGAQQEL-KEAIQQHRDDLAAFQKDKI 965
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLeRQAEKAERYKE------LKAELRELELALlVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  966 DLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLR 1045
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1046 QDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRAslwaQEAKAAQLQLQLRSTEAQLEAL 1125
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----LRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1126 VAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGdsvptpwgsdpdqngasrlLKRGPLLTALSAEAVALALQKL 1205
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE-------------------LEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1206 HQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVH-------------SELQDLQRQLSQSQEEKSKWE-GKQNSLESE 1271
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSELISVDEGYEaAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1272 LRDL----HETMASLQSRLRQAELQK-----MEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE------- 1335
Cdd:TIGR02168  547 LQAVvvenLNAAKKAIAFLKQNELGRvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvl 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1336 --EDLRTARSALKLKNEE-----IESERERAQALQEQGELKVAQG--------KALQENLTLLAQTLSNREREVETLQAE 1400
Cdd:TIGR02168  627 vvDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSilerrreiEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1401 VQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTA 1480
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1481 LEHQLLDLEQKAQVIESQ----RGQIQDLKKQLGTLECLALEL-----------EESHRKVEGQQKVITELEGQRELQRV 1545
Cdd:TIGR02168  787 LEAQIEQLKEELKALREAldelRAELTLLNEEAANLRERLESLerriaaterrlEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1546 ALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQ 1625
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958767517 1626 V-----LEDQRTLQTKIlEEDLEQIKHSLRERGQELAS 1658
Cdd:TIGR02168  947 EeysltLEEAEALENKI-EDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1377-2176 1.92e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.92e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1377 QENLTLLAQTLSNREREVETLQAEVQELEKQREMQK----AALELLSLDLKKRSREVDLQQEQIQELeqcRSVLEHLPMA 1452
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQAEKAERYKELKAelreLELALLVLRLEELREELEELQEELKEA---EEELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1453 VQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtlECLALELEESHRKVEGQQKV 1532
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL---EELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1533 ITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLER 1612
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1613 KGQElvlqkeriqvledQRTLQTKILEEDLEQIKHSLRERGQELASQwqlmQERAEDGKSPSKAQRGSLEHLKLILRDKE 1692
Cdd:TIGR02168  419 LQQE-------------IEELLKKLEEAELKELQAELEELEEELEEL----QEELERLEEALEELREELEEAEQALDAAE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1693 KEVECQQERIQELQehmgQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLE--------- 1763
Cdd:TIGR02168  482 RELAQLQARLDSLE----RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvenlna 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1764 --EAQRALAQ--------------RDHELEALRQEQQQTRGQ--------EESMKQKTSALQAALEQAHV--TLKE--RQ 1815
Cdd:TIGR02168  558 akKAIAFLKQnelgrvtflpldsiKGTEIQGNDREILKNIEGflgvakdlVKFDPKLRKALSYLLGGVLVvdDLDNalEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1816 GELEEHRGQVQRLQEELI----VEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQA 1888
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAElekALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1889 QATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR 1968
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1969 ARQLEEALRVREGEIQTQALQHQEAMQHLQQElcqkeedLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGL 2048
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESL-------ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2049 LES-LKELQLTVAQKEEEILMLREAQQRQNQEasspshrsfpaekpslqLLLAQQDLERLQNALRQTEAREIEWREKAQG 2127
Cdd:TIGR02168  871 LESeLEALLNERASLEEALALLRSELEELSEE-----------------LRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2128 LALSLAQSKASISSLQEI-AMFLQASVLERESEQQRLQEELVLSRQALEE 2176
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 992-1832 2.56e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  992 IEEKVREAQECSRIQKEL-EKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQVELLRQEVK 1070
Cdd:TIGR02168  205 LERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1071 EKEADFVAREAQLLEELEASRIAERQVRAslwaQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 1150
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQI----LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1151 GSACERRPELRGggdsvptpwgsdpdqngasrllkrgplltalsaeavalALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1230
Cdd:TIGR02168  354 ESLEAELEELEA--------------------------------------ELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1231 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQnsLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1310
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1311 SAQVEHLQACVTEARAQASAAGVLEEDLRT---ARSALKLKNEEIESERERAQALQE-QGELKVAQGKALQENLTLLAqt 1386
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGfseGVKALLKNQSGLSGILGVLSELISvDEGYEAAIEAALGGRLQAVV-- 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1387 lsnrereVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQ 1466
Cdd:TIGR02168  552 -------VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1467 IRELENDREAQRTALEHQLLDL-------------------EQKAQVIESQRGQIQDLKKQLgtleclalelEESHRKVE 1527
Cdd:TIGR02168  625 VLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKI----------EELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1528 GQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLT 1607
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1608 QDLERKGQELVLQKERIQVLEDQRTLQTKILEEdLEQIKHSLRERGQELASQWQLMQERAEdgkspskaqrgslehlkli 1687
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAELTLLNEEAANLRERLESLERRIA------------------- 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1688 lrDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ---GQLEE 1764
Cdd:TIGR02168  835 --ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELReleSKRSE 912

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 1765 AQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKE-RQGELEEHRGQVQRLQEEL 1832
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 220-917 3.80e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 3.80e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  220 LEKEAhEKSQELMQLKSQG-DLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMeheaSLSRNA 298
Cdd:TIGR02168  205 LERQA-EKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR----LEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  299 QEEKLSLQHVIKDITQALASVEEEDTVTQTpgSENSLQSDYNDLSQFDSQDPNKALTLVHSvLTRRQQAVQDLRQQLSGC 378
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRE--RLANLERQLEELEAQLEELESKLDELAEE-LAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  379 QEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRV 458
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  459 NVELQLQGDSAQGEKLEQ-----QEELHLAVRERERLQETLVGLEAKQSESLSELIAL---REALESSRLAGELLKQEQE 530
Cdd:TIGR02168  437 ELQAELEELEEELEELQEelerlEEALEELREELEEAEQALDAAERELAQLQARLDSLerlQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  531 EVAAALARAEQSI---------VELSSSENSLKAEVADLRAAAVKLGALNEA-------LALDKVALNQQLLQLEQENQS 594
Cdd:TIGR02168  517 GLSGILGVLSELIsvdegyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNelgrvtfLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  595 MC-------SRVEAAEQLRSALQ--------------------------------------------------------- 610
Cdd:TIGR02168  597 IEgflgvakDLVKFDPKLRKALSyllggvlvvddldnalelakklrpgyrivtldgdlvrpggvitggsaktnssilerr 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  611 VDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEAL 690
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  691 ARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQnsviqvtKSQLEVQIQTIIQAKEVI 770
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  771 QGEVKCLKLEL-DTERSHAEQERDAVARQLAQAE-QEGQAALERQKVAHEEEVNRLQEKWEKERALLQQkLDKTLETLER 848
Cdd:TIGR02168  830 ERRIAATERRLeDLEEQIEELSEDIESLAAEIEElEELIEELESELEALLNERASLEEALALLRSELEE-LSEELRELES 908

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517  849 ERTELEMKLREQHTETEALRAQREEERTQAD------SALYQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 917
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 902-1476 4.18e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  902 QTQKELADASQQLERL------------------RQDMKVQKLKEQETTgmLQAQLRGAQ--------QELKEAIQQHRD 955
Cdd:COG1196    176 EAERKLEATEENLERLedilgelerqleplerqaEKAERYRELKEELKE--LEAELLLLKlreleaelEELEAELEELEA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  956 DLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADS 1035
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1036 VRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQL 1115
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1116 RSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPwGSDPDQNGASRLLKRGPLLTALSA 1195
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1196 EAVALALQKLHQDL---WKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSEL----QDLQRQLSQSQEEKSKWEGKQNSL 1268
Cdd:COG1196    493 LLLLLEAEADYEGFlegVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1269 ESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLK 1348
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1349 NEEIESERERAQALQEQGELKVAQGKALQENLTLLAQtlSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSRE 1428
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA--EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1958767517 1429 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREA 1476
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 434-1161 1.45e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  434 LQTARGELQQQLEVLEQE---AWRLRRVNVEL-QLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELI 509
Cdd:TIGR02168  191 LEDILNELERQLKSLERQaekAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  510 ALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLE 589
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  590 QENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELrgAREEKEELKEKLNEAHHQQ 669
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL--ERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  670 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQ-QNSV 748
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  749 IQVTK--SQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQA------ALERQKVAHEEE 820
Cdd:TIGR02168  509 KALLKnqSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  821 VNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREeerTQADSALYQMQLETEKERVSLLETL 900
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK---LRPGYRIVTLDGDLVRPGGVITGGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  901 LQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAqLRGAQQELKEAIQQHRddlaafqKDKIDLQKQVEDLTSQLVT 980
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAE-LRKELEELEEELEQLR-------KELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  981 HNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGV 1060
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1061 QVELLRQEVKEKEADfVAREAQLLEELEASRIAERQVRASLwaqEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLR 1140
Cdd:TIGR02168  818 EAANLRERLESLERR-IAATERRLEDLEEQIEELSEDIESL---AAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          730       740
                   ....*....|....*....|.
gi 1958767517 1141 SLYSVLQQALGSACERRPELR 1161
Cdd:TIGR02168  894 SELEELSEELRELESKRSELR 914
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 780-1509 2.60e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 2.60e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  780 ELDTERSHAEQERDAVARQLAQAEqegqaALERQKVAHEEEVNRLQEKWEKERALLQQKLD-------KTLETLERERTE 852
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLD-----LIIDEKRQQLERLRREREKAERYQALLKEKREyegyellKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  853 LEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRqdmKVQKLKEQEtt 932
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE---RSIAEKERE-- 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  933 gmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKE 1012
Cdd:TIGR02169  317 ---LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1013 KASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEadfvareaQLLEELEASRI 1092
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE--------WKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1093 AERQvraSLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQA----------LGSACERRP---E 1159
Cdd:TIGR02169  466 KYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgtvaqLGSVGERYAtaiE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1160 LRGGGDSVPTPWGSDPDQNGASRLLKR-----------------GPLLTALS------------------AEAVALALQK 1204
Cdd:TIGR02169  543 VAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflplnkmrdeRRDLSILSedgvigfavdlvefdpkyEPAFKYVFGD 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1205 --LHQDLWKAQQARDDLR-------------------DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEG 1263
Cdd:TIGR02169  623 tlVVEDIEAARRLMGKYRmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1264 KQNSLESELRDLHETMASLQSRLRQAElqkMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARS 1343
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLE---QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1344 AL-----KLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELL 1418
Cdd:TIGR02169  780 ALndleaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1419 SLDLKKRSREVdlqQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELendrEAQRTALEHQLLDLEQKAQVIESQ 1498
Cdd:TIGR02169  860 NGKKEELEEEL---EELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL----EAQIEKKRKRLSELKAKLEALEEE 932

                          810
                   ....*....|.
gi 1958767517 1499 RGQIQDLKKQL 1509
Cdd:TIGR02169  933 LSEIEDPKGED 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1194-1905 3.24e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1194 SAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQ-----VHSELQDLQRQLSQSQEEKSKWEGKQNSL 1268
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1269 ESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASaagvleeDLRTARSALKLK 1348
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-------DYREKLEKLKRE 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1349 NEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSRE 1428
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1429 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRD-----------QIRELENDREAQRTALEHQL------------ 1485
Cdd:TIGR02169  478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYATAIEVAAgnrlnnvvvedd 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1486 LDLEQKAQVIESQRG---------QIQDLKKQLGTLECL------------ALELEESHRKVEGQQKVITELEGQRELQ- 1543
Cdd:TIGR02169  558 AVAKEAIELLKRRKAgratflplnKMRDERRDLSILSEDgvigfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRLMg 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1544 RVALTHLTLDLEERS---------------------QELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1602
Cdd:TIGR02169  638 KYRMVTLEGELFEKSgamtggsraprggilfsrsepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLERKGQELVLQKERI-QVLEDQRTLQTKILEEDLEQIKHSLR-ERGQELASQWQLMQERAEDGKSPSKAQ--R 1678
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLeELEEDLSSLEQEIENVKSELKELEARiEELEEDLHKLEEALNDLEARLSHSRIPeiQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1679 GSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEakeqgelreqvL 1758
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-----------L 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1759 QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLqEELIVEGRQ 1838
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-EDPKGEDEE 945

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1839 VRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLqDSWLQAQATLAEQEQELEALRAE 1905
Cdd:TIGR02169  946 IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILERIEE 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 794-1614 7.93e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 7.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  794 AVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKtLETLERERTELE----MKLREQHTETEALRA 869
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQ-LERLRREREKAEryqaLLKEKREYEGYELLK 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  870 QREEERTQADsalyqmqlETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEA 949
Cdd:TIGR02169  231 EKEALERQKE--------AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  950 IQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLV 1029
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1030 LQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEeLEASRiaeRQVRASLWAQEAKAA 1109
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE-LEEEK---EDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1110 QLQLQLRSTEAQLEALVAEQqpeNQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKR--- 1186
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEY---DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvge 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1187 ---GPLLTALSA---------EAVALALQKLHQD----------LWKAQQARDDL----RDQVQKLVQRLTDTEAQ-KSQ 1239
Cdd:TIGR02169  536 ryaTAIEVAAGNrlnnvvvedDAVAKEAIELLKRrkagratflpLNKMRDERRDLsilsEDGVIGFAVDLVEFDPKyEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1240 VHSELQDlqRQLSQSQEEKSKWEGKQN--SLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHL 1317
Cdd:TIGR02169  616 FKYVFGD--TLVVEDIEAARRLMGKYRmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1318 QACVTEARAQASAagvleedLRTARSALKLKNEEIESERERaqaLQEQGELKVAQGKALQENLTLLAQTLSNREREVETL 1397
Cdd:TIGR02169  694 QSELRRIENRLDE-------LSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1398 QAEVQELEKQREMQKAALEllSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQ 1477
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALN--DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1478 RTALEHQLLDLEQKaqvIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQqkvITELEGQRELQRVALTHLTLDLEER 1557
Cdd:TIGR02169  842 RIDLKEQIKSIEKE---IENLNGKKEELEEELEELEAALRDLESRLGDLKKE---RDELEAQLRELERKIEELEAQIEKK 915

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1558 SQELQTQSSQLHELENHSTRLAKELQErDQEVMSQRQQIEELQKQKEQLTQDLERKG 1614
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALE 971
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1220-1785 8.85e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.31  E-value: 8.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1220 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 1299
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1300 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 1379
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1380 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 1459
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1460 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 1539
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1540 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 1619
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1620 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 1699
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1700 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 1779
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767517 1780 RQEQQQ 1785
Cdd:PRK02224   714 YDEAEE 719
PTZ00121 PTZ00121
MAEBL; Provisional
 994-1806 1.97e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  994 EKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRelgvqvellrqeVKEKE 1073
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK------------AEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1074 ADFVAREAQLLEELEASRIAERqvraslwAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVlqqalgsa 1153
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAED-------AKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEA-------- 1217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1154 ceRRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDdlRDQVQKLVQRLTDT 1233
Cdd:PTZ00121  1218 --RKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKAD 1293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1234 EAQKSQVHSELQDLQRQlsqsQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQ 1313
Cdd:PTZ00121  1294 EAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1314 vehlQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1393
Cdd:PTZ00121  1370 ----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1394 VETLQAEVQELEKQREMQKAALELLSLD-LKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKlsvqrDQIRELEN 1472
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1473 DREAQrtalehQLLDLEQKAQVIESQRGQiqDLKKQLGTLECLALELEESHRKVEGQQKVitelegqrelqrvalthltl 1552
Cdd:PTZ00121  1521 AKKAD------EAKKAEEAKKADEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKA-------------------- 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1553 dlEERSQELQTQSSQLHELEnhstrlakelQERDQEVMSQRQqiEELQKQKEQLtqdleRKGQELVLQKERIQVLEDQRT 1632
Cdd:PTZ00121  1573 --EEDKNMALRKAEEAKKAE----------EARIEEVMKLYE--EEKKMKAEEA-----KKAEEAKIKAEELKKAEEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1633 LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlkliLRDKEKEVECQQERIQELQEHMGQL 1712
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---------AKKAEEDEKKAAEALKKEAEEAKKA 1704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1713 EQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEES 1792
Cdd:PTZ00121  1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                          810
                   ....*....|....
gi 1958767517 1793 MKQKTSALQAALEQ 1806
Cdd:PTZ00121  1785 LDEEDEKRRMEVDK 1798
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1216-2064 4.04e-12

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 72.29  E-value: 4.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1216 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEekskwegKQNSLESELRDLHETMASLQSRLRQAElqKME 1295
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSA-------RESDLEQDYQAASDHLNLVQTALRQQE--KIE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1296 A-QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkv 1370
Cdd:COG3096    351 RyQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAA---EEEVDSLKSQLADYQQALDVQQTRAiqyqQAVQ------- 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1371 AQGKAlQENLTLLAQTLSNREREVETLQAEVQELEKQRemqkaalellsLDLKKRSREVDLQQEQIQELEQcrsVLEHLP 1450
Cdd:COG3096    421 ALEKA-RALCGLPDLTPENAEDYLAAFRAKEQQATEEV-----------LELEQKLSVADAARRQFEKAYE---LVCKIA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1451 MAVqEREQKLSVQRDQIRELENDRE--AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEG 1528
Cdd:COG3096    486 GEV-ERSQAWQTARELLRRYRSQQAlaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEA 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1529 QQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQER---DQEVMSQRQQIEELQKQKEQ 1605
Cdd:COG3096    565 QLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATV 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1606 LTQDLERKGQELVLQKERIQVL---EDQRTLQTK---------------------------------ILEEDLEQIKHSL 1649
Cdd:COG3096    645 ERDELAARKQALESQIERLSQPggaEDPRLLALAerlggvllseiyddvtledapyfsalygparhaIVVPDLSAVKEQL 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1650 RERGQELASQWQLmqERAEDGKSPSKAQRGSLEHLKLIlrdKEKEVECQQERIQEL--------QEHMGQLEQQLQGLHR 1721
Cdd:COG3096    725 AGLEDCPEDLYLI--EGDPDSFDDSVFDAEELEDAVVV---KLSDRQWRYSRFPEVplfgraarEKRLEELRAERDELAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1722 KVGETSLllthREQEtatlQQRLQEAKEQ--GELREQVLQGQLEEAQRALAQR----DHELEALRQEQQQTRGQEESMKQ 1795
Cdd:COG3096    800 QYAKASF----DVQK----LQRLHQAFSQfvGGHLAVAFAPDPEAELAALRQRrselERELAQHRAQEQQLRQQLDQLKE 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1796 KTSALQAALEQAHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQA 1871
Cdd:COG3096    872 QLQLLNKLLPQANLladeTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQR 951

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1872 QEH-------EAEARTLQDSWLQAQATLAEQEQELEALR-----AENQYSRQQEEAAFGQAE---------ALQEALSKA 1930
Cdd:COG3096    952 RLKqqifalsEVVQRRPHFSYEDAVGLLGENSDLNEKLRarleqAEEARREAREQLRQAQAQysqynqvlaSLKSSRDAK 1031

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1931 QATLQEKEQRLleqAELSCTLEASTAtlqatlDTCQARARQLEEAL---RVREGEIQTQALQHQEAMQHLQQELCQKEED 2007
Cdd:COG3096   1032 QQTLQELEQEL---EELGVQADAEAE------ERARIRRDELHEELsqnRSRRSQLEKQLTRCEAEMDSLQKRLRKAERD 1102

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 2008 LRQQDEQRQ-------LLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE 2064
Cdd:COG3096   1103 YKQEREQVVqakagwcAVLRLARDNDVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEH 1166
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1337-1855 5.03e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 5.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1337 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 1409
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1410 MQKAALE--LLSLDLKKRSREV--DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 1485
Cdd:PRK02224   290 ELEEERDdlLAEAGLDDADAEAveARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1486 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 1565
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1566 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 1631
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1632 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 1705
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1706 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 1784
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1785 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 1855
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1593-2288 5.18e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 5.18e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1593 RQQIEELQKQKEQLTQDLERKGQ----ELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQELASQW-QLMQERA 1667
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAElrelELALLVLRLEELREEL-EELQEELKEAEEELEELTAELQELEEKLeELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1668 EDGKSPSKAQRGSLEHLKLIlRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEA 1747
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI-SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1748 KEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR 1827
Cdd:TIGR02168  357 EAELE----ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1828 LQEELIveGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQ 1907
Cdd:TIGR02168  433 AELKEL--QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA----QLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1908 YSRQQEEAAFGQAE-----------------ALQEALSK-AQATLQEKEQR------LLEQAELS-CTLEASTATLQATL 1962
Cdd:TIGR02168  507 GVKALLKNQSGLSGilgvlselisvdegyeaAIEAALGGrLQAVVVENLNAakkaiaFLKQNELGrVTFLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1963 DTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQeLCQKEEDLRQQDEQRQLLEKAV------------------AQ 2024
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG-GVLVVDDLDNALELAKKLRPGYrivtldgdlvrpggvitgGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2025 RSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEIL----MLREAQQRQNQEASSPSHRSFPAEKPSLQLLLA 2100
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEeleeELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2101 QQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 2180
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2181 -GPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRK 2259
Cdd:TIGR02168  826 lESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740
                   ....*....|....*....|....*....
gi 1958767517 2260 LkRDSLRASRAGSLEARETMNSSPTQQDG 2288
Cdd:TIGR02168  906 L-ESKRSELRRELEELREKLAQLELRLEG 933
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 670-1507 5.76e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 5.76e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  670 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQD-----LAEQVLGLRSAKEQLEGNLFEAQQ 744
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  745 QNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCL----KLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAhEEE 820
Cdd:TIGR02169  252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL-EAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  821 VNRLQEKWEKerallqqkLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADsalyqmqlETEKERVSLLETL 900
Cdd:TIGR02169  331 IDKLLAEIEE--------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA--------ETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  901 LQTQKELADASQQLERLRQDMKvqklkeqettgmlqaQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVT 980
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQ---------------RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  981 HNDSQRLVKQEIEEKVREaqecsriQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGv 1060
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEE-------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG- 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1061 QVELLRQEVKEKEA-----------DFVAREA-QLLEELEASRIaerqvrASLWAQEAKAAQLQLQLRSTEAQLEALVA- 1127
Cdd:TIGR02169  532 SVGERYATAIEVAAgnrlnnvvvedDAVAKEAiELLKRRKAGRA------TFLPLNKMRDERRDLSILSEDGVIGFAVDl 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1128 ---EQQPENQAQAQLRSlySVLQQALGSAceRRpelRGGGDSVPTPWGSDPDQNGA----SRLLKRGPLLTAL---SAEA 1197
Cdd:TIGR02169  606 vefDPKYEPAFKYVFGD--TLVVEDIEAA--RR---LMGKYRMVTLEGELFEKSGAmtggSRAPRGGILFSRSepaELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1198 VALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHE 1277
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1278 TMASLQSRLRQaelqkmeaqndrelLQASKEKLSAQVEHLQACVTEARAQASAAgvLEEDLRTARSALKLKNEEIESERE 1357
Cdd:TIGR02169  759 ELKELEARIEE--------------LEEDLHKLEEALNDLEARLSHSRIPEIQA--ELSKLEEEVSRIEARLREIEQKLN 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1358 RAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQ 1437
Cdd:TIGR02169  823 RLTLEKEYLEKEIQE---LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1438 eleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKK 1507
Cdd:TIGR02169  900 --------------ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED 955
PTZ00121 PTZ00121
MAEBL; Provisional
 612-1416 3.80e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  612 DLAEAERSREALWEEKTHLE----TQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQE 687
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEeakkTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  688 EA----LARAGQEKEALVRERAALEVRLQAVERDrqdlAEQVLGLRSAKeqlegnlfEAQQQNSVIQVTKSQLEVQIQTI 763
Cdd:PTZ00121  1162 DArkaeEARKAEDAKKAEAARKAEEVRKAEELRK----AEDARKAEAAR--------KAEEERKAEEARKAEDAKKAEAV 1229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  764 IQAKEVIQGEVKCLKLEldTERSHAEQERDAVARQLAQAEQegQAALERQKVAHEEEVNRLQEKwekerallqQKLDKTL 843
Cdd:PTZ00121  1230 KKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARR--QAAIKAEEARKADELKKAEEK---------KKADEAK 1296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  844 ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSlletllqtQKELADASQQLERLRQDMKV 923
Cdd:PTZ00121  1297 KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA--------KAEAEAAADEAEAAEEKAEA 1368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  924 QKLKEQETTGMLQAQLRGAQQ-----ELKEAIQQHRDDLAAFQKdKIDLQKQVEDLTSQLvthndSQRLVKQEIEEKVRE 998
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEEkkkadEAKKKAEEDKKKADELKK-AAAAKKKADEAKKKA-----EEKKKADEAKKKAEE 1442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  999 AQECSRIQKELEKEKASLTLSLVEKEKRllvlqEADSVRQRELVSLRQDiqEAQEGQRELGVQVELLRQEVKEKEADFVA 1078
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAK-----KADEAKKKAEEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEA 1515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1079 REAQLLEELEASRIAERQVRASlWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRP 1158
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKAD-EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1159 ElrgggdsvptpwgSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKS 1238
Cdd:PTZ00121  1595 E-------------EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1239 QVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQndrelLQASKEKLSAQVEHLQ 1318
Cdd:PTZ00121  1662 KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAK 1736

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1319 ACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGeLKVAQGKALQENLTLLAQTLSNREREVETLQ 1398
Cdd:PTZ00121  1737 KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-LDEEDEKRRMEVDKKIKDIFDNFANIIEGGK 1815

                          810
                   ....*....|....*...
gi 1958767517 1399 AEVQELEKQREMQKAALE 1416
Cdd:PTZ00121  1816 EGNLVINDSKEMEDSAIK 1833
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 776-1613 6.67e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  776 CLKLELDTERSHAEQERDAvARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEM 855
Cdd:pfam02463  191 DLEELKLQELKLKEQAKKA-LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQ 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  856 KLREQhteTEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGML 935
Cdd:pfam02463  270 VLKEN---KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  936 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1015
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1016 LTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER 1095
Cdd:pfam02463  427 EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1096 QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPElrgggdsvptpWGSDP 1175
Cdd:pfam02463  507 SGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL-----------TELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1176 DQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ 1255
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1256 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE 1335
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1336 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLlAQTLSNREREVETLQAEVQELEKQREMQKAAL 1415
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1416 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1495
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1496 ESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK-----VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHE 1570
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILlkyeeEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767517 1571 LENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1613
Cdd:pfam02463  975 VNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 363-1008 1.18e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  363 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARgELQ 442
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-EAK 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  443 QQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERErlqetlvGLEAKQSESLSELIALREALESSRLAG 522
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE-------AAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  523 ELLKQEQEEVAAALARAEQSIVELSSSENSLKAEvaDLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAA 602
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE--EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  603 EQLRSALQVDLAEAERSREAlwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQD 682
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKA--EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  683 AERQEEAlaRAGQEKEALVRERAALEVRLQAVERdrqdlAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT 762
Cdd:PTZ00121  1551 LKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  763 IIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE----EEVNRLQE---KWEKERALL 835
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaEEDEKKAAealKKEAEEAKK 1703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  836 QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSA---------LYQMQLETEKERVSLLETLLQTQKE 906
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdeeekkkIAHLKKEEEKKAEEIRKEKEAVIEE 1783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  907 LADASQQLERLRQDMKVQKLKE---------QETTGMLQAQLRGAQQELKEAI---QQHRDDLAAFQKDKIDlQKQVEDL 974
Cdd:PTZ00121  1784 ELDEEDEKRRMEVDKKIKDIFDnfaniieggKEGNLVINDSKEMEDSAIKEVAdskNMQLEEADAFEKHKFN-KNNENGE 1862

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1958767517  975 TSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1008
Cdd:PTZ00121  1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
PTZ00121 PTZ00121
MAEBL; Provisional
 1603-2277 1.18e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLERKGQELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQElaSQWQLMQERAEDGKSPSKAQRGSLE 1682
Cdd:PTZ00121  1043 KEKDIIDEDIDGNHEGKAEAKAHVGQDEG-LKPSYKDFDFDAKEDNRADEATE--EAFGKAEEAKKTETGKAEEARKAEE 1119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETAtlqQRLQEAKEQGELREQVLQGQL 1762
Cdd:PTZ00121  1120 AKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDA---KKAEAARKAEEVRKAEELRKA 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRALAQRDHE----LEALRQEQQQTRGQ-----EESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR-LQEEL 1832
Cdd:PTZ00121  1197 EDARKAEAARKAEeerkAEEARKAEDAKKAEavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAaIKAEE 1276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1833 IVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE--QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 1910
Cdd:PTZ00121  1277 ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1911 QQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleASTATLQATLDTCQARARQLEEALRVREGEIQTQALQH 1990
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK------ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEK 1430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1991 QEAmqhlqQELCQKEEDLRQQDE-QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 2069
Cdd:PTZ00121  1431 KKA-----DEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA 1505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2070 REAQQRQNQEASSpshrsfpAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQE--IAM 2147
Cdd:PTZ00121  1506 AEAKKKADEAKKA-------EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedKNM 1578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2148 FLQASVLERESEQQRLQEELVLSRQALE---EQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLER 2224
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKmkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE 1658

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767517 2225 LQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAGSLEARE 2277
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1539-1866 1.42e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1539 QRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQdlerkgqelv 1618
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1619 lqkeriqvlEDQRTLQTKI--LEEDLEQIKHSLRERGQELasqwQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVE 1696
Cdd:TIGR02169  287 ---------EEQLRVKEKIgeLEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1697 CQQERIQELQEHMGQLEQQLQGLHRKVGETslllthrEQETATLQQRLQEAKEqgelreqvlqgQLEEAQRALAQRDHEL 1776
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAET-------RDELKDYREKLEKLKR-----------EINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1777 EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREH 1856
Cdd:TIGR02169  416 QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          330
                   ....*....|
gi 1958767517 1857 EKTVLALQQR 1866
Cdd:TIGR02169  496 EAQARASEER 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 208-853 1.66e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  208 AQLLLLVAKTQALEKEAHEKSQELMQLKSQGDlekaELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAEL 287
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLD----ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  288 MEHEASLSRNAQEEKLSLQHVIKDITQALASVEEedtvtqtpgSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQA 367
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIASLNNEIERLEARLER---------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  368 VQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGE---VDSLSKERELLQTARGELQQQ 444
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFsegVKALLKNQSGLSGILGVLSEL 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  445 LEV---------------------------------LEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQ 491
Cdd:TIGR02168  529 ISVdegyeaaieaalggrlqavvvenlnaakkaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  492 ETLVGLEAKQSESLSELI---ALREALESSR----------LAGELLK-------------QEQEEVAAALARAEQSIVE 545
Cdd:TIGR02168  609 KFDPKLRKALSYLLGGVLvvdDLDNALELAKklrpgyrivtLDGDLVRpggvitggsaktnSSILERRREIEELEEKIEE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  546 LSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWE 625
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  626 EKTHLETQLRKAEETGAELQAELRGAREekeelkeklneahhQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERA 705
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKE--------------ELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  706 ALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCL---KLELD 782
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskRSELR 914

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517  783 TERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE---EEVNRLQEKWEKERALLQQKLDKtletLERERTEL 853
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltlEEAEALENKIEDDEEEARRRLKR----LENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 1454-2180 3.56e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.56e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1454 QEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV--IESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 1531
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETgkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1532 viTELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnhsTRLAKELQERDQ-------EVMSQRQQIEELQKQKE 1604
Cdd:PTZ00121  1148 --AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAEELRKAEDarkaeaaRKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1605 QLTQDLERKGQELVLQKERIQVLEDQRTLQtKILEEDLEQIKHSLRERGQELASQWQLMQE--RAEDGKSPSKAQRGslE 1682
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNE-EIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKA--E 1299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLILRDKEKEVEcqQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQvlqgQL 1762
Cdd:PTZ00121  1300 EKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK----KK 1373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRalaqrdhELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1842
Cdd:PTZ00121  1374 EEAKK-------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1843 EEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQatlaEQEQELEALRAENQYSRQQEEAAFGQAEA 1922
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE----EAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1923 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEE----ALRVREGEIQTQALQHQEAMQHLQ 1998
Cdd:PTZ00121  1523 KADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmALRKAEEAKKAEEARIEEVMKLYE 1602

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1999 QELCQKEEDLRQQDEQR---QLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEE----ILMLRE 2071
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKikaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKK 1682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2072 AQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREI---EWREKAQGLALSLAQSKASISSLQEIAMF 2148
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIkaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHL 1762

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1958767517 2149 LQASvlERESEQQRLQEELVLSRQALEEQQSR 2180
Cdd:PTZ00121  1763 KKEE--EKKAEEIRKEKEAVIEEELDEEDEKR 1792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1447-2261 3.74e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 3.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1447 EHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtleclaleLEESHRKV 1526
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1527 EGQ-QKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHEL--------------------------ENHSTRLA 1579
Cdd:pfam15921  144 RNQlQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeeasgkkiyehdsmstmhfRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1580 KELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQ-KERIQVLEDQRTLQTKILEEDleqiKHSLRERGQELAS 1658
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEK----ASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1659 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1738
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1739 TLQQRLQEAKEQGELREQVLQGQLEEAQRaLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlkERQGEL 1818
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS------ECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1819 EEHRGQVQRLQEELivegrqvraleEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQE 1898
Cdd:pfam15921  447 ERQMAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1899 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQlEEALRV 1978
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT-AGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1979 REGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEkaVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLT 2058
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2059 VAQKEEEILMLREAQQRQNQEASSPSHrsfpaeKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKAS 2138
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTN------KLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ 742

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2139 ISSLQEIAMFLQASVLERESEQQRLQEElvlsRQALEEQQSrgphsssradqgpkagqdtepgeVIEAEPSPGVGEKEQL 2218
Cdd:pfam15921  743 IDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELS-----------------------TVATEKNKMAGELEVL 795

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767517 2219 RQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLK 2261
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 394-1150 5.49e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 5.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  394 EEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELlQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEK 473
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAL-LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  474 LEQQ-EELHLAVRERERLQETLvgleAKQSESLS--ELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSE 550
Cdd:TIGR02169  256 LTEEiSELEKRLEEIEQLLEEL----NKKIKDLGeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  551 NSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHL 630
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  631 ETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVR 710
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  711 LQAVERDRQDLAEQVLGLRSAKEQLEGNL--------------------FEAQQQNSVIQVTKSQLEVQIQTIIQAKEVI 770
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIELLKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  771 QGEVKCLKL------ELDTERSHAEQERDaVARQLAQAEQEGQAAlerqkVAHEEEVNRLQEKWEKERALLQQKLDKTL- 843
Cdd:TIGR02169  572 AGRATFLPLnkmrdeRRDLSILSEDGVIG-FAVDLVEFDPKYEPA-----FKYVFGDTLVVEDIEAARRLMGKYRMVTLe 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  844 -ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLL-QTQKELADASQQLERLRQDM 921
Cdd:TIGR02169  646 gELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLdELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  922 KvQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLvtHNDSQRLVKQEIEEKVREAQE 1001
Cdd:TIGR02169  726 E-QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1002 csriqkeLEKEKASLTLSLVEKEKRLlvlqeadSVRQRELVSLRQDIQEAQEGQRELGVQvellRQEVKEKEADFVAREA 1081
Cdd:TIGR02169  803 -------LEEEVSRIEARLREIEQKL-------NRLTLEKEYLEKEIQELQEQRIDLKEQ----IKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 1082 QLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 1150
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 211-919 7.13e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 7.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  211 LLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEH 290
Cdd:TIGR02169  191 LIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  291 EASLS-------RNAQEEKLSLQHVIKDITQALASVE--EEDTVTQTPGSENSLQSDYNDLSQFDSQ--DPNKALTLVHS 359
Cdd:TIGR02169  271 EQLLEelnkkikDLGEEEQLRVKEKIGELEAEIASLErsIAEKERELEDAEERLAKLEAEIDKLLAEieELEREIEEERK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  360 VLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDalagqtvDLQGEVDSLSKERELLQTARG 439
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-------ELKRELDRLQEELQRLSEELA 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  440 ELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSR 519
Cdd:TIGR02169  424 DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  520 LAGELLKQEQEEVAAALARAEQSIVELSSSE------------NSLKAEVADLRAAAVKLGALNEA--------LALDKV 579
Cdd:TIGR02169  504 ERVRGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaagNRLNNVVVEDDAVAKEAIELLKRrkagratfLPLNKM 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  580 ALNQQLLQLEQENQSM--------------------------CSRVEAAEQL---------------RSALQVDLAEAER 618
Cdd:TIGR02169  584 RDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgdtlvVEDIEAARRLmgkyrmvtlegelfeKSGAMTGGSRAPR 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  619 SRE----ALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAG 694
Cdd:TIGR02169  664 GGIlfsrSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  695 QEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQ-IQTIIQAKEVIQGE 773
Cdd:TIGR02169  744 EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSrIEARLREIEQKLNR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  774 VKCLKLELDTERSHAEQERDAVARQLAQAEQEgQAALERQKVAHEEEVNrlqekwEKERALLQqkLDKTLETLERERTEL 853
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-IENLNGKKEELEEELE------ELEAALRD--LESRLGDLKKERDEL 894

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517  854 EMKLREQHTETEALRAQREEERTQAdsALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 919
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIEKKRKRL--SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1202-2019 7.19e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 7.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1202 LQKLHQDLWKAQQARDDLRDQVQK-LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkskwegkqnsleseLRDLHETMA 1280
Cdd:TIGR02169  203 LRREREKAERYQALLKEKREYEGYeLLKEKEALERQKEAIERQLASLEEELEKLTEE--------------ISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1281 SLQSRLRQAELQKMEAQNDREL-LQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERA 1359
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1360 QALQEQgelkvaqgkalqenltlLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL 1439
Cdd:TIGR02169  349 RKRRDK-----------------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1440 EQcrsVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALEL 1519
Cdd:TIGR02169  412 QE---ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1520 EESHRKVEGQQKVIteleGQRELQRVALTHLtldLEERSQELQTQSSQLHEL-ENHSTRLAKELQERDQEVMSQRqqiEE 1598
Cdd:TIGR02169  489 QRELAEAEAQARAS----EERVRGGRAVEEV---LKASIQGVHGTVAQLGSVgERYATAIEVAAGNRLNNVVVED---DA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1599 LQKQKEQLTQDlERKGQELVLQKERIQvleDQRTLQTKILEEDLEQIKHSLRERGQELAS------QWQLMQERAEDGK- 1671
Cdd:TIGR02169  559 VAKEAIELLKR-RKAGRATFLPLNKMR---DERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvfGDTLVVEDIEAARr 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1672 ---------------SPSKAQRG---SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHR 1733
Cdd:TIGR02169  635 lmgkyrmvtlegelfEKSGAMTGgsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1734 EQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ-----AH 1808
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQE----EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1809 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHE---AEARTLQDSW 1885
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1886 LQAQATLAEQEQELEAL-----RAENQYSRQQE--EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 1958
Cdd:TIGR02169  871 EELEAALRDLESRLGDLkkerdELEAQLRELERkiEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1959 qATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLE 2019
Cdd:TIGR02169  951 -LSLEDVQAELQRVEEEIR-ALEPVNMLAIQEYEEVLKRLDELKEKRAKL--EEERKAILE 1007
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
363-852 8.31e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 8.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  363 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVD-LQGEVDSLSKERELLQTARGEL 441
Cdd:COG4913    285 FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  442 QQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAV-----------RERERLQETLVGLEAKQSESLSELIA 510
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalrdlrRELRELEAEIASLERRKSNIPARLLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  511 LREALESS--------RLAGELL--KQEQEEVAAALARAeqsiveLSSSENSLKAEVADLRAAAVKLGALNEALALD--K 578
Cdd:COG4913    445 LRDALAEAlgldeaelPFVGELIevRPEEERWRGAIERV------LGGFALTLLVPPEHYAAALRWVNRLHLRGRLVyeR 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  579 VALNQQLLQLEQ-ENQSMCSRVEAAE-QLRSALQVDLAEAE-----RSREALWEEKTHL-ETQLRKAEETGAELqaelrG 650
Cdd:COG4913    519 VRTGLPDPERPRlDPDSLAGKLDFKPhPFRAWLEAELGRRFdyvcvDSPEELRRHPRAItRAGQVKGNGTRHEK-----D 593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  651 AREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQDLAEQVLGLRS 730
Cdd:COG4913    594 DRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDVASAEREIAE 672

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  731 AKEQLEgNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKclklELDTERSHAEQERDAVARQLAQAEQEGQAAL 810
Cdd:COG4913    673 LEAELE-RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIG----RLEKELEQAEEELDELQDRLEAAEDLARLEL 747

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 1958767517  811 E------RQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTE 852
Cdd:COG4913    748 RalleerFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 667-1403 9.19e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 9.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  667 HQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAE-QVLGLRSAKEQLEGNLFEAQQQ 745
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERS 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  746 NSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERshaeQERDAVARQLAQAEQEgqaalERQKVAHEEEVNRLQ 825
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER----KRRDKLTEEYAELKEE-----LEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 EKWEKERALLQQKLDKtletLERERTELEMKLREQHTETEALRAQREEERTQADSALYQM-QLETEKERVslletllqtQ 904
Cdd:TIGR02169  381 AETRDELKDYREKLEK----LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKInELEEEKEDK---------A 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  905 KELADASQQLERLRQDM---KVQKLKEQETTGMLQAQLRGAQQEL------KEAIQQHRDDLAAFQKDKIDLQKQVEDLT 975
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLskyEQELYDLKEEYDRVEKELSKLQRELaeaeaqARASEERVRGGRAVEEVLKASIQGVHGTV 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  976 SQLVTHND----------SQRLVKQEIEEKVrEAQECSRIQKELEKEKAS-LTLSLVEKEKRLLVLQEADSVRQRELVSL 1044
Cdd:TIGR02169  528 AQLGSVGEryataievaaGNRLNNVVVEDDA-VAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLV 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1045 RQDIQEAQEGQRELGVQVELLRQEVKEK---EADFVAREAQLLEE---LEASRIAERQVRASLWAQEAKAAQLQLQLRST 1118
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTLVVEDIEAARRlmgKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1119 EAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGggdsvptpwgsdpdqngasrllkrgplltalSAEAV 1198
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ-------------------------------EEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1199 ALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQS-----QEEKSKWEGKQNSLESELR 1273
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVSRIEARLR 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1274 DLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIE 1353
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1354 SERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQE 1403
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
478-1027 1.43e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.78  E-value: 1.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  478 EELHLAVRERERLQETLVGLEA------KQSESLSELIALREALES--SRLAGELLKQEQEEVAAALARAEQSIVELSSS 549
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRElaeryaAARERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  550 ENSLKAEVADLRAAAVKLGAlnealaldkvalnqqllqleqenqsmcSRVEAAEQLRSALQVDLAEAERSREALweekth 629
Cdd:COG4913    318 LDALREELDELEAQIRGNGG---------------------------DRLEQLEREIERLERELEERERRRARL------ 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  630 lETQLRKAEETGAELQAELRgareekeelkeklneahHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEV 709
Cdd:COG4913    365 -EALLAALGLPLPASAEEFA-----------------ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  710 RLQAVERDRQDLAEQVLGLRSA-KEQLE---------GNLF-----EAQQQNSVIQVTKSQ---LEVQIQTIIQAKEVI- 770
Cdd:COG4913    427 EIASLERRKSNIPARLLALRDAlAEALGldeaelpfvGELIevrpeEERWRGAIERVLGGFaltLLVPPEHYAAALRWVn 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  771 ----QGEVKCLKLELDTERSHAEQ-ERDAVARQLAQAEQEGQAALERQ--------KVAHEEEVNRLQ------------ 825
Cdd:COG4913    507 rlhlRGRLVYERVRTGLPDPERPRlDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvCVDSPEELRRHPraitragqvkgn 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 --------EKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADsaLYQMQLETEKERVSll 897
Cdd:COG4913    587 gtrhekddRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE--ALQRLAEYSWDEID-- 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  898 etLLQTQKELADASQQLERLRQDM-KVQKLKEQEttgmlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTS 976
Cdd:COG4913    663 --VASAEREIAELEAELERLDASSdDLAALEEQL------EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517  977 QLVTHNDSQRL-VKQEIEEKVREAQEC---SRIQKELEKEKASLTLSLVEKEKRL 1027
Cdd:COG4913    735 RLEAAEDLARLeLRALLEERFAAALGDaveRELRENLEERIDALRARLNRAEEEL 789
mukB PRK04863
chromosome partition protein MukB;
1226-2066 2.04e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 63.44  E-value: 2.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1226 LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElQKMEAQNDRELLQA 1305
Cdd:PRK04863   284 HLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQE-KIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1306 SKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkvaqgkALQENLT 1381
Cdd:PRK04863   363 RLEEQNEVVEEADEQQEENEARAEAA---EEEVDELKSQLADYQQALDVQQTRAiqyqQAVQ-----------ALERAKQ 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1382 LLAQ---TLSNREREVETLQAEVQElekqremqkAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEhlpmavQEREQ 1458
Cdd:PRK04863   429 LCGLpdlTADNAEDWLEEFQAKEQE---------ATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGE------VSRSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1459 KLSVQRDQIRELENDR--EAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITEL 1536
Cdd:PRK04863   494 AWDVARELLRRLREQRhlAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSES 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1537 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAK---ELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1613
Cdd:PRK04863   574 VSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREqsgEEFEDSQDVTEYMQQLLERERELTVERDELAAR 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1614 GQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHS-------LRERGQELASQWQLMQ----ERAEDGKSPSKAQRGSLE 1682
Cdd:PRK04863   654 KQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSeiyddvsLEDAPYFSALYGPARHaivvPDLSDAAEQLAGLEDCPE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLKLI------LRDKEKEVE-----------------------------CQQERIQELQEHMGQLEQQLQGLHRKVGETS 1727
Cdd:PRK04863   734 DLYLIegdpdsFDDSVFSVEelekavvvkiadrqwrysrfpevplfgraAREKRIEQLRAEREELAERYATLSFDVQKLQ 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1728 LLLTHREQETAT-LQQRLQEAKEQgelreqvlqgQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 1806
Cdd:PRK04863   814 RLHQAFSRFIGShLAVAFEADPEA----------ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPR 883

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1807 AHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEktvlalqqrcaeqaqeheaearTLQ 1882
Cdd:PRK04863   884 LNLladeTLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFE----------------------QLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1883 DSWLQAQATLAEQEQELEALRAENqysrqQEEAAFGQAEAlQEALSKAQAtLQEKEQRLLEQAELSCTlEASTATLQAtl 1962
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTEVV-----QRRAHFSYEDA-AEMLAKNSD-LNEKLRQRLEQAEQERT-RAREQLRQA-- 1011

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1963 dtcQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQR--QLLEKAVAQRSQENGIQEKQSLEqe 2040
Cdd:PRK04863  1012 ---QAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARrdELHARLSANRSRRNQLEKQLTFC-- 1086

                          890       900
                   ....*....|....*....|....*.
gi 1958767517 2041 kEEETRGLLESLKELQLTVAQKEEEI 2066
Cdd:PRK04863  1087 -EAEMDNLTKKLRKLERDYHEMREQV 1111
PTZ00121 PTZ00121
MAEBL; Provisional
 1207-1846 3.97e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1207 QDLWKAQQARDDLRDQVQKLVQRLTDTE-AQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSR 1285
Cdd:PTZ00121  1197 EDARKAEAARKAEEERKAEEARKAEDAKkAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE 1276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1286 LRQA-ELQKMEAQNDRELLQASKEKlsAQVEHLQACVTEARAQASAAGVLEEDLRTArSALKLKNEEiesERERAQALQE 1364
Cdd:PTZ00121  1277 ARKAdELKKAEEKKKADEAKKAEEK--KKADEAKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEE---AKKAAEAAKA 1350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1365 QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELlsldlKKRSREVDLQQEQIQELEQCRS 1444
Cdd:PTZ00121  1351 EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-----KKKADELKKAAAAKKKADEAKK 1425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1445 VLEHLPMAvqEREQKLSVQRDQIRELENDREAQRTALEhqlldLEQKAQviesQRGQIQDLKKQlgtlECLALELEESHR 1524
Cdd:PTZ00121  1426 KAEEKKKA--DEAKKKAEEAKKADEAKKKAEEAKKAEE-----AKKKAE----EAKKADEAKKK----AEEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1525 KVEGQQKVITELEGQRELQRVALthltldlEERSQELQTQSSQLHELEnhstrlakelqerdqevmsQRQQIEELQKQKE 1604
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKAD-------EAKKAEEAKKADEAKKAE-------------------EAKKADEAKKAEE 1544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1605 QLTQDLERKGQELVLQKERIQVLEDQRTLQTKILE----EDLEQIKHSLRERGQELASQWQLMqeRAEDGKSPSKAqRGS 1680
Cdd:PTZ00121  1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAlrkaEEAKKAEEARIEEVMKLYEEEKKM--KAEEAKKAEEA-KIK 1621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1681 LEHLKlilrdKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQG 1760
Cdd:PTZ00121  1622 AEELK-----KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQeQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGElEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:PTZ00121  1697 EAEEAKKAEELKKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIR 1774


                   ....*.
gi 1958767517 1841 ALEEVL 1846
Cdd:PTZ00121  1775 KEKEAV 1780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 163-736 4.24e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  163 DRDLTELKAEHARLSgsLLTCCLRLTLRAQSRDSSGSGRSDESEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEK 242
Cdd:COG1196    259 EAELAELEAELEELR--LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  243 AELQdrvtELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQAlasveee 322
Cdd:COG1196    337 EELE----ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL------- 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  323 dtvtqtpgsenslqsdyndlsqfdsqdpnkaltlvhsvltrrQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRER 402
Cdd:COG1196    406 ------------------------------------------EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  403 LQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHL 482
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  483 AVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRA 562
Cdd:COG1196    524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  563 AAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGA 642
Cdd:COG1196    604 VASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  643 ELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLA 722
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763

                          570
                   ....*....|....
gi 1958767517  723 EQVLGLRSAKEQLE 736
Cdd:COG1196    764 ELERELERLEREIE 777
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 988-1769 7.14e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 7.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  988 VKQEIEEKVREAQECSRIQK-ELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLR 1066
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1067 QEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVL 1146
Cdd:TIGR02169  276 ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1147 QQALGSACERRPELRGGGDSVPTPWGSDPDQNGASR------LLKRGPLLTALSaeAVALALQKLHQDLWKAQQARDDLR 1220
Cdd:TIGR02169  356 TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRekleklKREINELKRELD--RLQEELQRLSEELADLNAAIAGIE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1221 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1300
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1301 ELLQASKEKLSAQVEHL------QACVTEARAQASAAGVLEEDLRTARSALKLKNE------------EIESERERAQAL 1362
Cdd:TIGR02169  514 EVLKASIQGVHGTVAQLgsvgerYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1363 QEQGELKVAQgkalqeNLTLLAQTLSNREREVETLQAEVQELEKQRE-MQKAALELLSLDLKKRSRE-VDLQQEQIQELE 1440
Cdd:TIGR02169  594 SEDGVIGFAV------DLVEFDPKYEPAFKYVFGDTLVVEDIEAARRlMGKYRMVTLEGELFEKSGAmTGGSRAPRGGIL 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1441 QCRSVLEHLPMaVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDlkkqlgtleclalELE 1520
Cdd:TIGR02169  668 FSRSEPAELQR-LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ-------------EEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1521 ESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRlaKELQERDQEVMSQRQQIEELQ 1600
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1601 KQKEQLTQDLERKGQELVLQKERIQVLEDQRtlqtkileEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS 1680
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQEQR--------IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1681 LEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLqg 1760
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQ-- 961


                   ....*....
gi 1958767517 1761 QLEEAQRAL 1769
Cdd:TIGR02169  962 RVEEEIRAL 970
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
598-1143 7.65e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 7.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  598 RVEAAEQLRSALQvDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAhhQQEAATAQLQ 677
Cdd:COG4913    243 ALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEA--ELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  678 QLHQDAERQEEALARA-GQEKEALVRERAALEVRLQAVERDRQDLAEQV----LGLRSAKEQLEGNLFEAQQQNSVIQVT 752
Cdd:COG4913    320 ALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLaalgLPLPASAEEFAALRAEAAALLEALEEE 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  753 KSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERS-------HAEQERDAVARQLAQAEQEGQAALERQKVAHEEEvnrlq 825
Cdd:COG4913    400 LEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDALAEALGLDEAELPFVGELIEVRPEEE----- 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 eKWEK--ERALLQQKL-----DKTLETLER--ERTELEMKLREQHTETEALRAQREeeRTQADSALYQMQLETEKERvSL 896
Cdd:COG4913    475 -RWRGaiERVLGGFALtllvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERP--RLDPDSLAGKLDFKPHPFR-AW 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  897 LETLLQTQKELA--DASQQLERLRQDMKVQKL-KEQETTGMLQAQLRGAQQ------------ELKEAIQQHRDDLAAFQ 961
Cdd:COG4913    551 LEAELGRRFDYVcvDSPEELRRHPRAITRAGQvKGNGTRHEKDDRRRIRSRyvlgfdnraklaALEAELAELEEELAEAE 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  962 KDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEekVREAQEcsRIQkELEKEKASLTLSLVEkekrllvLQEAdsvrQREL 1041
Cdd:COG4913    631 ERLEALEAELDALQERREALQRLAEYSWDEID--VASAER--EIA-ELEAELERLDASSDD-------LAAL----EEQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1042 VSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQ 1121
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774

                          570       580
                   ....*....|....*....|..
gi 1958767517 1122 LEALVAEQQPENQAQAQLRSLY 1143
Cdd:COG4913    775 IDALRARLNRAEEELERAMRAF 796
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1700-1904 1.04e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1700 ERIQELQEHMGQLEqqlqGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 1779
Cdd:COG4913    225 EAADALVEHFDDLE----RAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1780 RQEQQQTRGQEESMKQKTSALQAALEQAHVT---------------LKERQGELEEHRGQVQRLQEELIVEGRQVRALEE 1844
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQirgnggdrleqlereIERLERELEERERRRARLEALLAALGLPLPASAE 380

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1845 VLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARtlqdswlQAQATLAEQEQELEALRA 1904
Cdd:COG4913    381 EFAALRAEAAALLEALEEELEALEEALAEAEAALR-------DLRRELRELEAEIASLER 433
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
886-1416 2.29e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 2.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  886 QLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKI 965
Cdd:COG4913    243 ALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRR---LELLEAELEELRAELARLEAELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  966 DLQKQVEDLTSQLVThNDSQRL--VKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVS 1043
Cdd:COG4913    320 ALREELDELEAQIRG-NGGDRLeqLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE---AAALLEA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1044 LRQDIQEAQEGQRELGVQVELLRQEVKEKEADfvareaqlLEELEA--SRIAERQVRA-SLWAQEAKAAQLQL------- 1113
Cdd:COG4913    396 LEEELEALEEALAEAEAALRDLRRELRELEAE--------IASLERrkSNIPARLLALrDALAEALGLDEAELpfvgeli 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1114 QLRSTEAQLEA-------------LVAEQQpENQAQAQLRSL-------YSVLQQALGSACERRPE---LRGGGDSVPTP 1170
Cdd:COG4913    468 EVRPEEERWRGaiervlggfaltlLVPPEH-YAAALRWVNRLhlrgrlvYERVRTGLPDPERPRLDpdsLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1171 WGSDPDQngasRLLKRGPLLTALSAE-------AVALALQ-KLHQDLWKAQQARD---------DLRDQVQKLVQRLTDT 1233
Cdd:COG4913    547 FRAWLEA----ELGRRFDYVCVDSPEelrrhprAITRAGQvKGNGTRHEKDDRRRirsryvlgfDNRAKLAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1234 EAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRdlhetMASLQSRLRQAELQKMEAQNDrellqaskeklSAQ 1313
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEID-----VASAEREIAELEAELERLDAS-----------SDD 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1314 VEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1393
Cdd:COG4913    687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766

                          570       580
                   ....*....|....*....|....
gi 1958767517 1394 V-ETLQAEVQELEKQREMQKAALE 1416
Cdd:COG4913    767 LrENLEERIDALRARLNRAEEELE 790
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
361-920 2.37e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 2.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  361 LTRRQQAVQDLRQQLsgcqEAMSFLQQQHNQWEEegkaLRERLQKLTGERDALAGQTvdLQGEVDSLSKERELLQTARGE 440
Cdd:COG4913    237 LERAHEALEDAREQI----ELLEPIRELAERYAA----ARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  441 LQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQ--------QEELHLAVRERERLQETLVGLEAKQSESLSELIALR 512
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRLEQlereierlERELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  513 EALESSRlagELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKL--------GALNEALALDKVALNQq 584
Cdd:COG4913    387 AEAAALL---EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGLDEAELPF- 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  585 llqleqenqsMCSRVE----------AAEQ-LRSALQVDLAEAERSREAL-WEEKTHLETQLRkAEETGAELQAELRGAR 652
Cdd:COG4913    463 ----------VGELIEvrpeeerwrgAIERvLGGFALTLLVPPEHYAAALrWVNRLHLRGRLV-YERVRTGLPDPERPRL 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  653 EEKEELKEKLNEAHHQQEAATAQLQQLH--------QDAERQEEALARAGQEKEALVRERAalevrlqaveRDRQDLAEQ 724
Cdd:COG4913    532 DPDSLAGKLDFKPHPFRAWLEAELGRRFdyvcvdspEELRRHPRAITRAGQVKGNGTRHEK----------DDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  725 -VLGL--RSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERshAEQERDAVARQLAQ 801
Cdd:COG4913    602 yVLGFdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELER 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  802 AEQEGQ--AALERQKVAHEEEVNRLQEKWEkERALLQQKLDKTLETLERERTELEMKLReqhtetEALRAQREEERTQAD 879
Cdd:COG4913    680 LDASSDdlAALEEQLEELEAELEELEEELD-ELKGEIGRLEKELEQAEEELDELQDRLE------AAEDLARLELRALLE 752

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1958767517  880 SALYQMQLE--TEKERVSLLETLLQTQKELADASQQLERLRQD 920
Cdd:COG4913    753 ERFAAALGDavERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1185-1414 2.44e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1185 KRGPLLTALSAEAVALALQKLHQDlwkAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGK 1264
Cdd:COG4942      1 MRKLLLLALLLALAAAAQADAAAE---AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1265 QNSLESELRDLHETMASLQSRLRQ---------AELQKMEAQNDRELLQASK---------EKLSAQVEHLQACVTEARA 1326
Cdd:COG4942     78 LAALEAELAELEKEIAELRAELEAqkeelaellRALYRLGRQPPLALLLSPEdfldavrrlQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1327 QASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEK 1406
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEA 234


                   ....*...
gi 1958767517 1407 QREMQKAA 1414
Cdd:COG4942    235 EAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1203-2024 2.79e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1203 QKLHQDLWKAQQARD----DLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHET 1278
Cdd:pfam01576  200 EKGRQELEKAKRKLEgestDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQED 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1279 MASLQSRLRQAELQKMEAQNDRELL--------------QASKEKLSAQVEHLQACVTEARAQASAAgvLEEDLRTARSA 1344
Cdd:pfam01576  280 LESERAARNKAEKQRRDLGEELEALkteledtldttaaqQELRSKREQEVTELKKALEEETRSHEAQ--LQEMRQKHTQA 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1345 LKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQEL-------EKQREMQKAALEL 1417
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqarlsesERQRAELAEKLSK 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1418 LSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIES 1497
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1498 qrgQIQDLKKQLgtleclalelEESHRKVEGQQKVITEL-EGQRELQRvalthltlDLEERSQELQTQSSQLHELENHST 1576
Cdd:pfam01576  518 ---QLSTLQAQL----------SDMKKKLEEDAGTLEALeEGKKRLQR--------ELEALTQQLEEKAAAYDKLEKTKN 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1577 RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDL-ERKGQELVLQKERIQVLEDQRTLQTKILeedleqikhslrergqE 1655
Cdd:pfam01576  577 RLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLaEEKAISARYAEERDRAEAEAREKETRAL----------------S 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1656 LASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVecqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQ 1735
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNV-------HELERSKRALEQQVEEMKTQLEELEDELQATED 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1736 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQ 1815
Cdd:pfam01576  714 AKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKK---LELDLKELEAQIDAAN 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1816 GELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQ 1895
Cdd:pfam01576  791 KGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAE-LLQLQEDLAASERARRQAQQERDELADE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1896 EQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE-LSCTLEASTATLQATLDTCQARARQLEE 1974
Cdd:pfam01576  870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEqLTTELAAERSTSQKSESARQQLERQNKE 949

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1975 aLRVREGEIQTQA-LQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 2024
Cdd:pfam01576  950 -LKAKLQEMEGTVkSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRR 999
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1324-2048 4.72e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1324 ARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQE-QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 1402
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1403 ELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL------------EQCRSVLEHLPMAVQ---EREQKLSVQRD-- 1465
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigeleaeiASLERSIAEKERELEdaeERLAKLEAEIDkl 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1466 --QIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEeshRKVEGQQKVITELEGQRELQ 1543
Cdd:TIGR02169  335 laEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1544 RVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELV-LQKE 1622
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSkLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1623 RIQVLEDQRTLQT---------KILEEDLEQIKHSLRERGQeLASQWQLMQERAEDGKSPS----------------KAQ 1677
Cdd:TIGR02169  492 LAEAEAQARASEErvrggraveEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRLNNvvveddavakeaiellKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1678 RGS------LEHLKLILRDKEKE------------VECQQ----------------ERIQELQEHMGQ-----LEQQL-- 1716
Cdd:TIGR02169  571 KAGratflpLNKMRDERRDLSILsedgvigfavdlVEFDPkyepafkyvfgdtlvvEDIEAARRLMGKyrmvtLEGELfe 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1717 -----QGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1791
Cdd:TIGR02169  651 ksgamTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE----LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1792 SMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREhektvlalqqrcaEQA 1871
Cdd:TIGR02169  727 QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-------------SRI 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1872 QEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTL 1951
Cdd:TIGR02169  794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1952 EASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGI 2031
Cdd:TIGR02169  874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL 953

                          810
                   ....*....|....*..
gi 1958767517 2032 QEKQSLEQEKEEETRGL 2048
Cdd:TIGR02169  954 EDVQAELQRVEEEIRAL 970
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1728-2180 5.77e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.43  E-value: 5.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1728 LLLTHREQETATLQQRLQEAKEQGELREQVlqGQLEEAQRALAQ-----RDH---ELEALRQEQQQTRGQEEsmkqkTSA 1799
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMAREL--EELSARESDLEQdyqaaSDHlnlVQTALRQQEKIERYQED-----LEE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1800 LQAALEQAHVTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDL-RAESREHEKtvlALQQRCAEQAQEheaea 1878
Cdd:COG3096    359 LTERLEEQEEVVEEAAEQLAEAEARLEAAEEE-------VDSLKSQLADYqQALDVQQTR---AIQYQQAVQALE----- 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1879 rtlqdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLleqaELSCTLEASTATL 1958
Cdd:COG3096    424 --------KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAY----ELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1959 QAtldtcQARARQLEEALRvregeiqtqALQHQ-EAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSL 2037
Cdd:COG3096    492 QA-----WQTARELLRRYR---------SQQALaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQ--LDAAEEL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2038 EQEKEEETrglleslkelqltvAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllAQQDLERLQNALRQTEAR 2117
Cdd:COG3096    556 EELLAELE--------------AQLEELEEQAAEAVEQRSE---------------------LRQQLEQLRARIKELAAR 600

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767517 2118 EIEWREKAQGLALSLAQSKASISSLQEIAMFLQaSVLERESEQQRLQEELVLSRQALEEQQSR 2180
Cdd:COG3096    601 APAWLAAQDALERLREQSGEALADSQEVTAAMQ-QLLEREREATVERDELAARKQALESQIER 662
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1817-2010 7.80e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 7.80e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1817 ELEEHRGQVQRLQEELIVEGRQVRALEEVLGD------LRAESREHEKTVLALQQRCAEQAQEH-EAEARTLQDSWLQAQ 1889
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELaeryaaARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1890 ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR 1968
Cdd:COG4913    309 AELERLEARLDALREElDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1958767517 1969 ARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 2010
Cdd:COG4913    389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
PTZ00121 PTZ00121
MAEBL; Provisional
 1232-1939 9.67e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 9.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1232 DTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKME----AQNDRELLQASK 1307
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEearkAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1308 EKLSAQVEHLQACVTEARAQASAAGV---------LEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQE 1378
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEevrkaeelrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1379 NLTLLAQTLSNREREVETLQAEVQELEKQREMQKAAlELLSLDLKKRSREVDLQQEQIQELEQCRSvlehlpmavqEREQ 1458
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEKKKADEAKKAEEKKKA----------DEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1459 KLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtlECLALELEESHRKVEGQQKVITELEG 1538
Cdd:PTZ00121  1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1539 QRELQRVALthltlDLEERSQELQTQSSQLHELENHSTRlAKELQERDQEVmsqrQQIEELQKQKEQltqdlERKGQELV 1618
Cdd:PTZ00121  1386 KAEEKKKAD-----EAKKKAEEDKKKADELKKAAAAKKK-ADEAKKKAEEK----KKADEAKKKAEE-----AKKADEAK 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1619 LQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLilRDKEKEVECQ 1698
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA--EEAKKADEAK 1528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1699 QERIQELQEHMGQLEQQLQGLHRKVGETsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEA 1778
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEE---LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1779 LRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 1858
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1859 TvlalQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKE 1938
Cdd:PTZ00121  1686 D----EKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757


                   .
gi 1958767517 1939 Q 1939
Cdd:PTZ00121  1758 K 1758
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1579-2061 1.06e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1579 AKELQERDQEVMSQRQQIEELQKQKEQLTQdLERKGQELVLQKERIQVLEDQRTLQTKileEDLEQIKHSLRERGQELAS 1658
Cdd:COG4913    227 ADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRL---WFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1659 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDK--------EKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 1730
Cdd:COG4913    303 ELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1731 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ-------EQQQTRGQ-EESMKQKTSAL-- 1800
Cdd:COG4913    383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDAlAEALGLDEAELpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1801 --------------QAALEQA------------------------------HVTLKERQGELEEHRGQV--QRLQEELIV 1834
Cdd:COG4913    463 vgelievrpeeerwRGAIERVlggfaltllvppehyaaalrwvnrlhlrgrLVYERVRTGLPDPERPRLdpDSLAGKLDF 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1835 EGRQVRA-LEEVLG------------DLRAESR-------------EHEK-------TVLALQQRCAEQAQEHEAEARTL 1881
Cdd:COG4913    543 KPHPFRAwLEAELGrrfdyvcvdspeELRRHPRaitragqvkgngtRHEKddrrrirSRYVLGFDNRAKLAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1882 QDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQealskAQATLQEKEQRLLEQAELSCTLEAstatLQAT 1961
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS-----AEREIAELEAELERLDASSDDLAA----LEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1962 LDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEE-DLRQQDEQRQLLEKAVAQRSQENGIQE-KQSLEQ 2039
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERFAAALGDAVERElRENLEE 773

                          570       580
                   ....*....|....*....|..
gi 1958767517 2040 EKEEETRGLLESLKELQLTVAQ 2061
Cdd:COG4913    774 RIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1393-1944 1.62e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1393 EVETLQAEVQELEK-QREMQKAA--LELLSlDLKKRSREVDLQQEQIQELEQCRSVLEHlpmavQEREQKLSVQRDQIRE 1469
Cdd:COG4913    226 AADALVEHFDDLERaHEALEDAReqIELLE-PIRELAERYAAARERLAELEYLRAALRL-----WFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1470 LENDR---EAQRTALEHQLLDLEQKAQVIESQR-----GQIQDLKKQLGTLECLALELEESHRKVEGQQKVI-----TEL 1536
Cdd:COG4913    300 LRAELarlEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAALglplpASA 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1537 EGQRELQRVALTHLtldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQI----EELQKQKEQLTQDLER 1612
Cdd:COG4913    380 EEFAALRAEAAALL----EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1613 KGQELVLQKERIQVLEDQ-----------RTLQTKIL--EEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPsKAQRG 1679
Cdd:COG4913    456 DEAELPFVGELIEVRPEEerwrgaiervlGGFALTLLvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERP-RLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1680 SLEHlKLILRDKEKEvecqqeriQELQEHMGQleqqlQGLHRKVGETSLLLTHREQETATLQ----QRLQEAKEQGELRE 1755
Cdd:COG4913    535 SLAG-KLDFKPHPFR--------AWLEAELGR-----RFDYVCVDSPEELRRHPRAITRAGQvkgnGTRHEKDDRRRIRS 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1756 QVLQGQleEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE--QAHVTLKERQGELEEHRGQVQRLQEE-- 1831
Cdd:COG4913    601 RYVLGF--DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAEle 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1832 -LIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEaEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 1910
Cdd:COG4913    679 rLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLEERFAA 757

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1958767517 1911 QQEEAAFGQ-AEALQEALSKAQATLQEKEQRLLEQ 1944
Cdd:COG4913    758 ALGDAVERElRENLEERIDALRARLNRAEEELERA 792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1243-2093 1.95e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1243 ELQDLQRQLSQSQE--EKSKWEgkqnsleselrdLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQvehLQAC 1320
Cdd:pfam15921   86 QVKDLQRRLNESNElhEKQKFY------------LRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ---LQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1321 VTEARAqasaAGVLEEDLrtarsalkLKNEEIESERERAQALQEQGelkvaqgkALQENLTLLaqtlsnrereVETLQAE 1400
Cdd:pfam15921  151 VHELEA----AKCLKEDM--------LEDSNTQIEQLRKMMLSHEG--------VLQEIRSIL----------VDFEEAS 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1401 VQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE-QCRSVLEHLPMAVQER-EQKLSVQRDQIRELENDREAQR 1478
Cdd:pfam15921  201 GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIfPVEDQLEALKSESQNKiELLLQQHQDRIEQLISEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1479 TALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLAleleeshrkvegqqkvITELEGQRELQRVALTHLTLDLEERS 1558
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ----------------LSDLESTVSQLRSELREAKRMYEDKI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1559 QELQTQssqlheLENHSTRLAKELQERDQevmsQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRT------ 1632
Cdd:pfam15921  345 EELEKQ------LVLANSELTEARTERDQ----FSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTgnsiti 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1633 --LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE-DGKSPSKAQRGSL----EHLKLILRDKEKEVECQQERIQEL 1705
Cdd:pfam15921  415 dhLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAiQGKNESLEKVSSLtaqlESTKEMLRKVVEELTAKKMTLESS 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1706 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVlQGQLEEAQRALAQRDHELEALRQEQQQ 1785
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNV-QTECEALKLQMAEKDKVIEILRQQIEN 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1786 TRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRlqeelivEGRQVRALEEVLGDLRAESrehEKTVLALQQ 1865
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDK-------KDAKIRELEARVSDLELEK---VKLVNAGSE 643

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1866 RCaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFG----QAEALQEALSKAQATLQEKEQRL 1941
Cdd:pfam15921  644 RL-RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmQLKSAQSELEQTRNTLKSMEGSD 722

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1942 LEQAELSCTLEASTATLQATLDTCQARARQLEEALrvregeiqTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLEKA 2021
Cdd:pfam15921  723 GHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM--------TNANKEKHFLKEEKNKLSQELSTV--ATEKNKMAGEL 792

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 2022 VAQRSQENGIQEKQSleqEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 2093
Cdd:pfam15921  793 EVLRSQERRLKEKVA---NMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKP 861
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1596-1941 3.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 3.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1596 IEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTLQTKILEEDLEQIKH--SLRERGQELAsQWQLMQERaedgksp 1673
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENI----ERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYE-GYELLKEK------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1674 sKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKV----GETSLLLTHREQETATLQQRLQEAKE 1749
Cdd:TIGR02169  233 -EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1750 QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQ 1829
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1830 EELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEALRAENQYS 1909
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958767517 1910 RQQEEAAFGQAEALQEALSKAQATLQEKEQRL 1941
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1622-2079 4.11e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1622 ERIQVLEDQRTLQTKILEEDLEQikhslRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER 1701
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQ-----REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1702 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelreqvlqgqLEEAQRALAQRDHELEALRQ 1781
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR-----------LEECRVAAQAHNEEAESLRE 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1782 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRaESREHEKTVL 1861
Cdd:PRK02224   350 DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR-EERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1862 ALQQRCAEQAQEHEAEARTLQDSWLQAQ-----------ATLAEQEQELEALRAENQYSRQQEEAAFGQAEALqEALSKA 1930
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGKCPEcgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1931 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQH---LQQELCQKEED 2007
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKER 587

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 2008 LRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRgllESLKELQLTVAQKEEEILMLREAQQRQNQE 2079
Cdd:PRK02224   588 IESLERIRTLLAAIADAEDEIERLREKREALAELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKE 656
PTZ00121 PTZ00121
MAEBL; Provisional
 1335-2057 4.24e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1335 EEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAA 1414
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1415 lELLSLDLKKRSREVDLQQEQIQEleqcrsvlEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV 1494
Cdd:PTZ00121  1174 -DAKKAEAARKAEEVRKAEELRKA--------EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1495 IESQRGQIQDLKKQlgtlECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnh 1574
Cdd:PTZ00121  1245 AEEERNNEEIRKFE----EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-- 1318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1575 stRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEdlEQIKHSLRERGQ 1654
Cdd:PTZ00121  1319 --EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1655 ELASQWQLMQERAEDGKSPSKAQRGSLEhlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHRE 1734
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADE-----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1735 QETATLQQRLQEAKEQGELREQVLQGQ--LEEAQRALAQRDHELEALRQEQ----QQTRGQEESMK-------------- 1794
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEakkaDEAKKAEEAKKadeakkaeekkkad 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1795 --QKTSALQAALEQAHVTLKERQgelEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQAQ 1872
Cdd:PTZ00121  1550 elKKAEELKKAEEKKKAEEAKKA---EEDKNMALRKAEEA-------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1873 EHEAEARTLQDswLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLE 1952
Cdd:PTZ00121  1620 IKAEELKKAEE--EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1953 ASTATLQATLDTCQARARQLEEALRVREGEIQTQAlqhqeamqhlqqelcqkEEDLRQQDEQRQLLEKAVAQRSQENGIQ 2032
Cdd:PTZ00121  1698 AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-----------------EEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760

                          730       740
                   ....*....|....*....|....*
gi 1958767517 2033 EKQSLEQEKEEETRGLLESLKELQL 2057
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEEL 1785
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1455-2181 4.27e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1455 EREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQ-IQDLKKQLGTLECLALELEESHRKVEGQQKVI 1533
Cdd:pfam02463  195 LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKEN 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1534 TELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErk 1613
Cdd:pfam02463  275 KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE-- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1614 gqelvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS---LEHLKLILRD 1690
Cdd:pfam02463  353 -----AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELArqlEDLLKEEKKE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1691 KEKEVECQQERIQELQEHMGQLEQQLQglhrKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALA 1770
Cdd:pfam02463  428 ELEILEEEEESIELKQGKLTEEKEELE----KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1771 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRgqvqrlqEELIVEGRQVRALEEVLGDLR 1850
Cdd:pfam02463  504 KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA-------TADEVEERQKLVRALTELPLG 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1851 AESREHEKTVLalqqRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENqySRQQEEAAFGQAEALQEALSKA 1930
Cdd:pfam02463  577 ARKLRLLIPKL----KLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI--LKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1931 QATLQEKeqrLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 2010
Cdd:pfam02463  651 GVSLEEG---LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2011 QDEQRQLLEKAVAQRSQENGIQEKqslEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPA 2090
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2091 EKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLS 2170
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730
                   ....*....|.
gi 1958767517 2171 RQALEEQQSRG 2181
Cdd:pfam02463  885 KDELESKEEKE 895
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1761-1987 5.10e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 5.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAE---SREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAF 1917
Cdd:COG4942    101 AQKEELAELLRAlyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1918 GQAEALQEALSKAQAtlqekeqrllEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQA 1987
Cdd:COG4942    181 AELEEERAALEALKA----------ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1256-2131 8.83e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 8.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1256 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElQKMEAQNDRELLQASKEKLsAQVEHLQACVTEARaqasaagVLE 1335
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAK-KALEYYQLKEKLELEEEYL-LYLDYLKLNEERID-------LLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1336 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAAL 1415
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1416 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1495
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1496 ESQRGQIQDLKKQLGTLECLALELEEShrKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHS 1575
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELE--ILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1576 TRLAKELQERDQEVMSQRQQIEELQKQKEQLtqDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQE 1655
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVL--LALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1656 LASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQ 1735
Cdd:pfam02463  560 VEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1736 ETATLQQRLQEAKEQGELReqvlqGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQ 1815
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGL-----AEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1816 GELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHE-KTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAE 1894
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRlKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1895 QEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEE 1974
Cdd:pfam02463  795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLL 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1975 ALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEK---------QSLEQEKEEET 2045
Cdd:pfam02463  875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEeepeellleEADEKEKEENN 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2046 RGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHR---SFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWR 2122
Cdd:pfam02463  955 KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELekeRLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWN 1034


                   ....*....
gi 1958767517 2123 EKAQGLALS 2131
Cdd:pfam02463 1035 KVFFYLELG 1043
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1456-1796 8.94e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.36  E-value: 8.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1456 REQKLSVQRDQIRELEN-DREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGqqkvIT 1534
Cdd:pfam17380  279 QHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER----IR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1535 ELEGQRELQRValthltldleeRSQELQTQSSQLHELEnhstRLAKELQERDQEVmsqRQQIEELQKQKeQLTQDLERKG 1614
Cdd:pfam17380  355 QEERKRELERI-----------RQEEIAMEISRMRELE----RLQMERQQKNERV---RQELEAARKVK-ILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1615 QELVLQKERIQV-LEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlklilRDKEK 1693
Cdd:pfam17380  416 QQQKVEMEQIRAeQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELE----------KEKRD 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1694 EVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRD 1773
Cdd:pfam17380  486 RKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEER 565

                          330       340
                   ....*....|....*....|...
gi 1958767517 1774 HELEALRQEQQQTRGQEESMKQK 1796
Cdd:pfam17380  566 SRLEAMEREREMMRQIVESEKAR 588
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1533-2067 9.84e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1533 ITELEGQRELQRVALTHLTLDL---EERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 1609
Cdd:PRK02224   222 IERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1610 LERKGQELVLQKERIQVLEDQRT-LQTKILEEDLEQIKH-----SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEH 1683
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEeLRDRLEECRVAAQAHneeaeSLREDADDLEERAEELREEAAELESELEEAREAVED 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1684 LKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQ-L 1762
Cdd:PRK02224   382 RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQpV 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1763 EEAQRA--LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAaleqahvtLKERQGELEEHRGQVQRLQEELIVEGRQVR 1840
Cdd:PRK02224   462 EGSPHVetIEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAESREHEktvlalqqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQysrqqeeaAFGQA 1920
Cdd:PRK02224   534 EKRERAEELRERAAELE-----------AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE--------SLERI 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQEKEQRLLEQAELSctleastATLQATLDTCQARARQLEEAlrVREGEIQTQALQHQEAMQHLQQe 2000
Cdd:PRK02224   595 RTLLAAIADAEDEIERLREKREALAELN-------DERRERLAEKRERKRELEAE--FDEARIEEAREDKERAEEYLEQ- 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2001 lcqKEEDLRQQDEQRQLLEKAVAqrSQENGIQEKQSLEQEKE--EETRGLLESLK------------------------- 2053
Cdd:PRK02224   665 ---VEEKLDELREERDDLQAEIG--AVENELEELEELRERREalENRVEALEALYdeaeelesmygdlraelrqrnvetl 739

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1958767517 2054 ------------------------ELQLTVAQKEEEIL 2067
Cdd:PRK02224   740 ermlnetfdlvyqndayshieldgEYELTVYQKDGEPL 777
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1190-1722 1.01e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 1.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1190 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ-EEKSKWEGKQNSL 1268
Cdd:COG4913    271 LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERL 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1269 ESELRDLHETMASLQSRLRQAELQkmeaqndrelLQASKEKLSAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLK 1348
Cdd:COG4913    351 ERELEERERRRARLEALLAALGLP----------LPASAEEFAALRAEAAALLEALEEELEA---LEEALAEAEAALRDL 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1349 NEEIESERERAQALQEQgelKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKA--------ALELL-- 1418
Cdd:COG4913    418 RRELRELEAEIASLERR---KSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfALTLLvp 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1419 SLDLKKRSREVDLQQEQIqeleqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLL------------ 1486
Cdd:COG4913    495 PEHYAAALRWVNRLHLRG------RLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGrrfdyvcvdspe 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1487 DLEQKAQVIeSQRGQIqdlkKQLGTLECLALELEESHRKVEGQ--QKVITELEGQRELQRVALThltlDLEERSQELQTQ 1564
Cdd:COG4913    569 ELRRHPRAI-TRAGQV----KGNGTRHEKDDRRRIRSRYVLGFdnRAKLAALEAELAELEEELA----EAEERLEALEAE 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1565 SSQLHELENHSTRLAkELQERDQEVMSQRQQIEELQKQKEQLTQ---DLERKGQELVLQKERIQVLEDQRT-LQTKI--L 1638
Cdd:COG4913    640 LDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDeLKGEIgrL 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1639 EEDLEQIkhslrergQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQ-QERIQELQEHMGQLEQQLQ 1717
Cdd:COG4913    719 EKELEQA--------EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDALRARLNRAEEELE 790


                   ....*
gi 1958767517 1718 GLHRK 1722
Cdd:COG4913    791 RAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 215-775 1.25e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  215 AKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKAlRGTMEILETNHAELMEHEASL 294
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA-DEAKKAEEKKKADEAKKKAEE 1313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  295 SRNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDlsqfDSQDPNKALTLVHSVLTRRQQAVQDLRQQ 374
Cdd:PTZ00121  1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE----AAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  375 LSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVD-LQGEVDSLSKERELLQTArgELQQQLEVLEQEAW 453
Cdd:PTZ00121  1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADeAKKKAEEAKKADEAKKKA--EEAKKAEEAKKKAE 1467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  454 RLRRVNVELQLQGDSAQGEKLEQ--QEELHLAVRERERLQETLVGLEAKQSESLSELIALREAlESSRLAGELLKQEQEE 531
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA-EEAKKADEAKKAEEKK 1546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  532 VAAALARAEqsivELSSSENSLKAEVADlRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVE----AAEQLRS 607
Cdd:PTZ00121  1547 KADELKKAE----ELKKAEEKKKAEEAK-KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeakkAEEAKIK 1621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  608 ALQVDLAEAERSREALWEEKTHLET----QLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDA 683
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKkkaeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  684 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQvlglrsaKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTI 763
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED-------KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                          570
                   ....*....|..
gi 1958767517  764 IQAKEVIQGEVK 775
Cdd:PTZ00121  1775 KEKEAVIEEELD 1786
mukB PRK04863
chromosome partition protein MukB;
1577-1972 1.54e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.81  E-value: 1.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1577 RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERiqvledqrtlqTKILEEDLEQIKHSLrergqel 1656
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEA-----------ESDLEQDYQAASDHL------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1657 asqwQLMQERAEDGKSPSKAQrGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLThrEQE 1736
Cdd:PRK04863   338 ----NLVQTALRQQEKIERYQ-ADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALD--VQQ 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1737 TATLQ-----QRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAAL------- 1804
Cdd:PRK04863   411 TRAIQyqqavQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRkiagevs 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1805 -EQAHVTLKERQGELEEHRGQVQRLQE------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAE 1877
Cdd:PRK04863   491 rSEAWDVARELLRRLREQRHLAEQLQQlrmrlsELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQ----LQEELEAR 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1878 ARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEE---AAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEAS 1954
Cdd:PRK04863   567 LESLSESVSEARERRMALRQQLEQLQARIQRLAARAPawlAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVE 646

                          410
                   ....*....|....*...
gi 1958767517 1955 TATLQATLDTCQARARQL 1972
Cdd:PRK04863   647 RDELAARKQALDEEIERL 664
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1213-1905 1.96e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.51  E-value: 1.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1213 QQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQ 1292
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1293 KMEAQNDR----ELLQASKEKLSAQVEHLQACVTEAR-AQASAAGVLE--EDLRTARSALKL--KNEEIESERERAQALQ 1363
Cdd:TIGR00606  428 ADEIRDEKkglgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRILEldQELRKAERELSKaeKNSLTETLKKEVKSLQ 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1364 -EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSL--DLKKRSREVDLQQEQIQELE 1440
Cdd:TIGR00606  508 nEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgYFPNKKQLEDWLHSKSKEIN 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1441 QCRSVLEHLPMAVQEREQklsvQRDQIRELENDREAQRTALEHQLLDL---EQKAQVIESQRGQIQDLKKQLGTLECLAL 1517
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQ----NKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAMLAGATA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1518 ELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERsqeLQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIE 1597
Cdd:TIGR00606  664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSK---LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIID 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1598 ELQKQKEQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQ 1677
Cdd:TIGR00606  741 LKEKEIPELRNKLQKVNRD--IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGS 818

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1678 RG--SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslLLTHREQETATLQQRlQEAKEQGELRE 1755
Cdd:TIGR00606  819 DLdrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE---LKSEKLQIGTNLQRR-QQFEEQLVELS 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1756 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEelive 1835
Cdd:TIGR00606  895 TEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKD----- 969

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1836 gRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEarTLQDSWLQAQATLAEQEQELEALRAE 1905
Cdd:TIGR00606  970 -DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ--KIQERWLQDNLTLRKRENELKEVEEE 1036
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 397-1062 2.21e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  397 KALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVL-EQEAWRLRRVNVELQLQGDSAQG---E 472
Cdd:TIGR02169  233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERsiaE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  473 KLEQQEELHLAVR----ERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARA-------EQ 541
Cdd:TIGR02169  313 KERELEDAEERLAkleaEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETrdelkdyRE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  542 SIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSRE 621
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  622 ALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAG------- 694
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAgnrlnnv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  695 --------QEKEALVRERAALEV------RLQAVERDRQDLAE----------------------QVLG-------LRSA 731
Cdd:TIGR02169  553 vveddavaKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEdgvigfavdlvefdpkyepafkYVFGdtlvvedIEAA 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  732 KEQ--------LEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDT---ERSHAEQERDAvARQLA 800
Cdd:TIGR02169  633 RRLmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlqsELRRIENRLDE-LSQEL 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  801 QAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQkLDKTLETLERERTELEMKLREQHTETEALRAQREE-ERTQAD 879
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSH 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  880 SALYQMQLET---EKERVSL----------LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQEL 946
Cdd:TIGR02169  791 SRIPEIQAELsklEEEVSRIearlreieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  947 KE---AIQQHRDDLAAFQKDKIDLQKQVEDLTS---------QLVTHNDSQRLVK--------QEIEEKVREAQECS--- 1003
Cdd:TIGR02169  871 EEleaALRDLESRLGDLKKERDELEAQLRELERkieeleaqiEKKRKRLSELKAKlealeeelSEIEDPKGEDEEIPeee 950

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767517 1004 ----RIQKELEK-EKASLTLSLV---------EKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQV 1062
Cdd:TIGR02169  951 lsleDVQAELQRvEEEIRALEPVnmlaiqeyeEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
mukB PRK04863
chromosome partition protein MukB;
1866-2180 2.48e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 2.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1866 RCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSrQQEEAAFGQ--------------AEALQEALSKAQ 1931
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAEL-NEAESDLEQdyqaasdhlnlvqtALRQQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1932 ATLQEKEQRLLEQAELSCT---------------------LEASTATLQATLDTCQARARQLEEALRVRE---------- 1980
Cdd:PRK04863   355 ADLEELEERLEEQNEVVEEadeqqeenearaeaaeeevdeLKSQLADYQQALDVQQTRAIQYQQAVQALErakqlcglpd 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1981 ----------GEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEE------ 2044
Cdd:PRK04863   435 ltadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQrhlaeq 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2045 TRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPS--------------HRSFPAEKPSLQLLLAQQDLERLQNA 2110
Cdd:PRK04863   515 LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDeleqlqeelearleSLSESVSEARERRMALRQQLEQLQAR 594

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2111 LRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAsVLERESEQQRLQEELVLSRQALEEQQSR 2180
Cdd:PRK04863   595 IQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQ-LLERERELTVERDELAARKQALDEEIER 663
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 277-573 2.83e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 2.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  277 MEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALAsvEEEDTVTQTPGSENSLQSDYNDLSQF--DSQDPNKAL 354
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK--ELEELSRQISALRKDLARLEAEVEQLeeRIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  355 TLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELL 434
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  435 QTARGELQQQLEVLEQEAWRLRRVNVELQLQGD-------SAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSE 507
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEeleseleALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517  508 LIALREALESSRLAGELLKQEQEEVAAALAR--------AEQSIVELSSSENSLKAEVADLRAAAVKLGALNEA 573
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeAEALENKIEDDEEEARRRLKRLENKIKELGPVNLA 990
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1465-1980 2.96e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 2.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1465 DQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ-RELQ 1543
Cdd:PRK03918   210 NEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElKELK 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1544 RVALTHLTLdlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKER 1623
Cdd:PRK03918   290 EKAEEYIKL--SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1624 IQVLEDQRTLQTKI---------------------LEEDLEQIKHSLRERGQELASQWQLMQE-RAEDGKSPSKAQRGSL 1681
Cdd:PRK03918   368 KAKKEELERLKKRLtgltpeklekeleelekakeeIEEEISKITARIGELKKEIKELKKAIEElKKAKGKCPVCGRELTE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1682 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQetatlqqrlqeAKEQGELREQVLQGQ 1761
Cdd:PRK03918   448 EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKEL-----------AEQLKELEEKLKKYN 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1762 LEEAQRAlaqrDHELEALRQEQQQTRGQEESMKQKTSALQaALEQAHVTLKERQGELEEHRGQVQRLQEELIVEgrQVRA 1841
Cdd:PRK03918   517 LEELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGFE--SVEE 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1842 LEEVLGDLRAESREHEKTVLALQqrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAE-NQYSRQQEEAAFGQA 1920
Cdd:PRK03918   590 LEERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKRLEELRKElEELEKKYSEEEYEEL 664

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQEKEQRLLEQAElscTLEASTATLQATLDTCQARARQLEEALRVRE 1980
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRRE---EIKKTLEKLKEELEEREKAKKELEKLEKALE 721
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1687-2262 3.00e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 3.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1687 ILRDKEKEVECQQERIQELQEHmgQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGElreqvlqgQLEEAQ 1766
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE--------EHEERR 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1767 RALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVL 1846
Cdd:PRK02224   251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1847 GDLRAESREHEKTVLALQQRCA---EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAEnqysrqqeeaafgqAEAL 1923
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADdleERAEELREEAAELESELEEAREAVEDRREEIEELEEE--------------IEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1924 QEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR---ARQLEEALRVREGEIQTQALQHQEAMQHLQQE 2000
Cdd:PRK02224   397 RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERveeAEALLEAGKCPECGQPVEGSPHVETIEEDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2001 LCQKEEDLRQQDEQRQLLEKAVAQrsqengiqEKQSLEQEKEEETrgLLESLKELQLTVAQKEEEILMLREAQQRQNQEA 2080
Cdd:PRK02224   477 VEELEAELEDLEEEVEEVEERLER--------AEDLVEAEDRIER--LEERREDLEELIAERRETIEEKRERAEELRERA 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2081 SspshrsfpaekpslqllLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMfLQASVLERESEQ 2160
Cdd:PRK02224   547 A-----------------ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRT-LLAAIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2161 QRLQEElvlsRQALEEQQS-RGPHSSSRADQGPKAGQDTEPGEVIEAEpspgvGEKEQLRQRLERLQQAVAELEVDRSKL 2239
Cdd:PRK02224   609 ERLREK----REALAELNDeRRERLAEKRERKRELEAEFDEARIEEAR-----EDKERAEEYLEQVEEKLDELREERDDL 679

                          570       580
                   ....*....|....*....|...
gi 1958767517 2240 QCHNAQLRTTLEQVERERRKLKR 2262
Cdd:PRK02224   680 QAEIGAVENELEELEELRERREA 702
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 732-1298 3.04e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 3.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  732 KEQLEGNLFEAQQQnsvIQVTKSQLEVQIQTIIQAKEViqgEVKCLKLELDTERSHAEQERDAVARQLAQAEQEgQAALE 811
Cdd:pfam15921  244 EDQLEALKSESQNK---IELLLQQHQDRIEQLISEHEV---EITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMYM 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  812 RQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTEL-EMKLREQHTETEALRAQREEERTQADSALYQMQLETE 890
Cdd:pfam15921  317 RQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELtEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  891 KERVSLLE--------TLLQTQKELADASQQLERLRQDMKVQKlkeQETTGMLQAQLrGAQQELKEAIQQHRDDLAAFQK 962
Cdd:pfam15921  397 KEQNKRLWdrdtgnsiTIDHLRRELDDRNMEVQRLEALLKAMK---SECQGQMERQM-AAIQGKNESLEKVSSLTAQLES 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  963 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSL---------------VEKEKRL 1027
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLqelqhlknegdhlrnVQTECEA 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1028 LVLQEADSVRQRELvsLRQDIQE-----AQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLW 1102
Cdd:pfam15921  553 LKLQMAEKDKVIEI--LRQQIENmtqlvGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1103 AQE----AKAAQLQLQ-LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACErrpELRGGGDSVPTPWGSDPDQ 1177
Cdd:pfam15921  631 ELEkvklVNAGSERLRaVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE---EMETTTNKLKMQLKSAQSE 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1178 NGASRLLKRGPLLTALSAEAVALALQKlhqDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEE 1257
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQK---QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1958767517 1258 KSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQN 1298
Cdd:pfam15921  785 KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1217-1832 3.50e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 3.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1217 DDLRDQVQKLVQRLTDTEaqksQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEA 1296
Cdd:PRK03918   144 DESREKVVRQILGLDDYE----NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1297 QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQgELKVAQGKAL 1376
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1377 QENLTLLAQTLSNREREVETLQAEVQELEKQREmqkaalellslDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1456
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIK-----------ELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1457 EQKLsVQRDQIRELENDREAQRtaLEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV---- 1532
Cdd:PRK03918   368 KAKK-EELERLKKRLTGLTPEK--LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgre 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1533 ITELEGQRELQRvalthLTLDLEERSQELQTQSSQLHELENHSTRLAKELqERDQEVMSQRQQIEELQKQKEQLT----Q 1608
Cdd:PRK03918   445 LTEEHRKELLEE-----YTAELKRIEKELKEIEEKERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKkynlE 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1609 DLERKGQELVLQKERIQVLE-DQRTLQTKI-----LEEDLEQIKHSLRERGQELASqwqLMQERAEDGKSPSKAQRGSLE 1682
Cdd:PRK03918   519 ELEKKAEEYEKLKEKLIKLKgEIKSLKKELekleeLKKKLAELEKKLDELEEELAE---LLKELEELGFESVEELEERLK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1683 HLK------LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslllthreqetatLQQRLQEA-KEQGELRE 1755
Cdd:PRK03918   596 ELEpfyneyLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE--------------LRKELEELeKKYSEEEY 661

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1756 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQgELEEHRGQVQRLQEEL 1832
Cdd:PRK03918   662 EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE-RVEELREKVKKYKALL 737
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1202-1806 3.72e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 3.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1202 LQKLHQDLWKAQQARDDLR------DQVQKLVQRLTDTEAQKSQVhsELQDLQRQLSQSQEEKSKWEGKQNSLESELRDL 1275
Cdd:COG4913    237 LERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1276 HETMASLQSRLRQAELQKMEAQNDRellqasKEKLSAQVEHLQAcvtEARAQASAAGVLEEDLRTARSALKLKNEEIESE 1355
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDR------LEQLEREIERLER---ELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1356 RERAQALQEQGElkvAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQR----EMQKAALELLSLDLKKRSREVdl 1431
Cdd:COG4913    386 RAEAAALLEALE---EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAEL-- 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1432 qqeqiqeleqcRSVLEHLPMAVQEREQKLSVQRdqirELENdreaQRTALehqLLDLEQKAQVIE-------SQRGQIQD 1504
Cdd:COG4913    461 -----------PFVGELIEVRPEEERWRGAIER----VLGG----FALTL---LVPPEHYAAALRwvnrlhlRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1505 LKKQLGTLECLALELEESHRKVEGQQKVITElEGQRELQRVALTHLTLDLEERSQELQ--TQSSQLHeleNHSTRLAKEL 1582
Cdd:COG4913    519 VRTGLPDPERPRLDPDSLAGKLDFKPHPFRA-WLEAELGRRFDYVCVDSPEELRRHPRaiTRAGQVK---GNGTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1583 QERDQEV----MSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqELAs 1658
Cdd:COG4913    595 RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1659 qwQLMQERAEDGKSPSKaqrgsLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthrEQETA 1738
Cdd:COG4913    672 --ELEAELERLDASSDD-----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA--------------EEELD 730

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767517 1739 TLQQRLQEAkeqGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 1806
Cdd:COG4913    731 ELQDRLEAA---EDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1216-1884 3.86e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1216 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELR---------------DLHETMA 1280
Cdd:pfam15921  305 QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARterdqfsqesgnlddQLQKLLA 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1281 SLQSRLRQAELQKMEAQN--DREL--------LQASKEKLSAQVEHLQACVTEARAQASaaGVLEEDLrtarSALKLKNE 1350
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRlwDRDTgnsitidhLRRELDDRNMEVQRLEALLKAMKSECQ--GQMERQM----AAIQGKNE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1351 EIEsereRAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKqremqkaALELLSLDLKKRSREVD 1430
Cdd:pfam15921  459 SLE----KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER-------AIEATNAEITKLRSRVD 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1431 lqqeqiqeleqcrsvlehlpMAVQEReQKLSVQRDQIRELENDREAQRtalehqlLDLEQKAQVIESQRGQIQDLKKQLG 1510
Cdd:pfam15921  528 --------------------LKLQEL-QHLKNEGDHLRNVQTECEALK-------LQMAEKDKVIEILRQQIENMTQLVG 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1511 ----TLECLALELEESHRKVEGQQKVITELEGQRELQRVALThltlDLEERSQELQTQSSQLHELENHSTRLAKEL-QER 1585
Cdd:pfam15921  580 qhgrTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR----ELEARVSDLELEKVKLVNAGSERLRAVKDIkQER 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1586 DQ---EVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQvledqrtLQTKILEEDLEQIKHSLRERGQELASQWQL 1662
Cdd:pfam15921  656 DQllnEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK-------MQLKSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1663 mqerAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGL----HRKVGETSLLLTHR---EQ 1735
Cdd:pfam15921  729 ----AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVatekNKMAGELEVLRSQErrlKE 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1736 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALrqeqqQTRGQEESMKQKTSALQ-AALEQAHVTLKER 1814
Cdd:pfam15921  805 KVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKEL-----QGPGYTSNSSMKPRLLQpASFTRTHSNVPSS 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1815 QGE---LEEHRGQVQRLQE-------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDS 1884
Cdd:pfam15921  880 QSTasfLSHHSRKTNALKEdptrdlkQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSS 959
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
630-1096 4.18e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 4.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  630 LETQLRKAEETgaELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALaragQEKEALVRERAALEV 709
Cdd:PRK02224   192 LKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR----EELETLEAEIEDLRE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  710 RLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAE 789
Cdd:PRK02224   266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  790 QERDAVARQLAQAE--QEGQAALERQKVAHEEEVNRLQEKWEKerallqqkLDKTLETLERERTELEMKLREQHTETEAL 867
Cdd:PRK02224   346 SLREDADDLEERAEelREEAAELESELEEAREAVEDRREEIEE--------LEEEIEELRERFGDAPVDLGNAEDFLEEL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  868 RAQREEERtqADSALYQMQLETEKERVSLLETLLQTQK-----------------------------ELADASQQLERLR 918
Cdd:PRK02224   418 REERDELR--EREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveeleaELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  919 QDM-KVQKLKEQETTgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVR 997
Cdd:PRK02224   496 ERLeRAEDLVEAEDR---IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  998 EAQECSRIQKELEKEKASLTlslvekekrllvlqeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFV 1077
Cdd:PRK02224   573 EVAELNSKLAELKERIESLE-------------------RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKR 633

                          490
                   ....*....|....*....
gi 1958767517 1078 AREAQLLEELEASRIAERQ 1096
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAR 652
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 751-1068 4.45e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 4.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  751 VTKSQLEVQIQTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVA----RQLAQAEQEGQAALERQKVAHEEEVNRLQ 825
Cdd:pfam17380  265 MTENEFLNQLLHIVQHQKAVSERQQQEKFEkMEQERLRQEKEEKAREverrRKLEEAEKARQAEMDRQAAIYAEQERMAM 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 EKWEKERALLQQKLDKTLETLERERTELEM-KLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslleTLLQTQ 904
Cdd:pfam17380  345 ERERELERIRQEERKRELERIRQEEIAMEIsRMRELERLQMERQQKNERVRQELEAARKVKILEEERQR-----KIQQQK 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  905 KELADASQQLERLRQDmKVQKLKEQETTGMlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDltsQLVTHNDS 984
Cdd:pfam17380  420 VEMEQIRAEQEEARQR-EVRRLEEERAREM--ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD---RKRAEEQR 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  985 QRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVSLRQDIQEAQEGQRELGVQVEL 1064
Cdd:pfam17380  494 RKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER---RKQQEMEERRRIQEQMRKATEERSRLEA 570


                   ....
gi 1958767517 1065 LRQE 1068
Cdd:pfam17380  571 MERE 574
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 780-901 4.63e-06

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 52.01  E-value: 4.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  780 ELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQ--QKLDKTLETLERERTELEMKL 857
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEeiQELKEELEQRYGKIPELEKEL 494

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767517  858 REQHTETEALRAQREEERTQADSA----------LYQMqLETEKERVSLLETLL 901
Cdd:COG0542    495 AELEEELAELAPLLREEVTEEDIAevvsrwtgipVGKL-LEGEREKLLNLEEEL 547
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1218-1832 6.00e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 6.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1218 DLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElqkmeaq 1297
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKE------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1298 NDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQ 1377
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1378 ENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDlqqeqiqeleqcrsvlehlpmavqERE 1457
Cdd:TIGR04523  232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIK------------------------ELE 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1458 QKLSVQRDQIRELENDREaqrtalehQLLDLEQKAQvIESQRGQIQDLKKQLGTLeclaleleeshrkvegqQKVITELE 1537
Cdd:TIGR04523  288 KQLNQLKSEISDLNNQKE--------QDWNKELKSE-LKNQEKKLEEIQNQISQN-----------------NKIISQLN 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1538 GQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL 1617
Cdd:TIGR04523  342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1618 VLQKERIQVLEDQRTLQTKILeEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEC 1697
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEI-KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1698 QQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEqgELREQVLQGQLEEAQRALAQRDHELE 1777
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEIEELKQTQK 578

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517 1778 ALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEEL 1832
Cdd:TIGR04523  579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 373-882 8.50e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 8.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  373 QQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDAL--------AGQTVDLQGEVDSLSKERELLQTA------- 437
Cdd:pfam12128  340 ETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRrskikeqnNRDIAGIKDKLAKIREARDRQLAVaeddlqa 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  438 -----RGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKlEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALR 512
Cdd:pfam12128  420 leselREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP-ELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  513 EALESSRLAGELLKQEQEEVAAALARAEQSIVELSSS-ENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQE 591
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTlLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGEL 578

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  592 NQ-SMCSRVEaaeqlrsalQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQE 670
Cdd:pfam12128  579 NLyGVKLDLK---------RIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALK 649

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  671 AATAQLQQLHQDAERQEEALARAGQEKEALVRER-AALEVRLQAVERDRQDLAEQVLGlrsakEQLEGNLFEAQQQNSVI 749
Cdd:pfam12128  650 NARLDLRRLFDEKQSEKDKKNKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKE-----QKREARTEKQAYWQVVE 724

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  750 QVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTER----------SHAEQERDAVARQLAQAEQEGQAALERQKVahee 819
Cdd:pfam12128  725 GALDAQLALLKAAIAARRSGAKAELKALETWYKRDLaslgvdpdviAKLKREIRTLERKIERIAVRRQEVLRYFDW---- 800

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767517  820 evnrLQEKWEKERallqQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSAL 882
Cdd:pfam12128  801 ----YQETWLQRR----PRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQ 855
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 849-1082 8.84e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  849 ERTELEMKLREQHTETEALRAQREEERTQADSALYQMQlETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE 928
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  929 QETTGMLQAQLRGAQQelkeaiqQHRDDLAAFqkdkIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1008
Cdd:COG4942    100 EAQKEELAELLRALYR-------LGRQPPLAL----LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 1009 LEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQ 1082
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1320-1544 9.15e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 9.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1320 CVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQA 1399
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1400 EVQELEKQREMQKAALELLSLDLKKRSR----EVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDRE 1475
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1476 AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQ-QKVITELEGQRELQR 1544
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEElEALIARLEAEAAAAA 240
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1554-2263 9.59e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 9.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1554 LEERSQELQTQSSQLHELENHSTrLAKELQERDQEVMSQrqQIEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTL 1633
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQA-LLKEKREYEGYELLK--EKEALERQKEAIERQLASLEEEL----EKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1634 QTKILEEDLEQIKHSLRERGQELASQwqlMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLE 1713
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLR---VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1714 QQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQV--LQGQLEEAQRALAQRDHELEALRQEQQQTRGQE 1790
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEvDKEFAETRDELkdYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1791 ESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLAL--QQRCA 1868
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeaQARAS 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1869 EQAQEHEAEARTLQDSWLQAQATLAEQeqeleALRAENQYSRQQEEAAFGQAEALQ-EALSKAQATLQEKEQRLL----- 1942
Cdd:TIGR02169  503 EERVRGGRAVEEVLKASIQGVHGTVAQ-----LGSVGERYATAIEVAAGNRLNNVVvEDDAVAKEAIELLKRRKAgratf 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1943 --------EQAELSCTLEASTATLQATLDTCQARAR--------------QLEEALR----VREGEIQTQALQHQEAMQH 1996
Cdd:TIGR02169  578 lplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvveDIEAARRlmgkYRMVTLEGELFEKSGAMTG 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1997 LQQELCQKEEDLRQQDEQRQLL--EKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLtvAQKEEEILMLREAQQ 2074
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPAELQRLreRLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE--IEKEIEQLEQEEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2075 RQNQEASSPSHRSFpaekpSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSK-----ASISSLQEIAMFL 2149
Cdd:TIGR02169  736 KERLEELEEDLSSL-----EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeiqAELSKLEEEVSRI 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2150 QASVLERESEQQRLQEELVLSRQALEEQQSRGPHSSSRADQgpkagqdtepgevIEAEPSPGVGEKEQLRQRLERLQQAV 2229
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS-------------IEKEIENLNGKKEELEEELEELEAAL 877

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1958767517 2230 AELEVDRSKLqchnaqlrttleqvERERRKLKRD 2263
Cdd:TIGR02169  878 RDLESRLGDL--------------KKERDELEAQ 897
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 361-575 9.98e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 9.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  361 LTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGE 440
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  441 LQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRL 520
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517  521 AgelLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALA 575
Cdd:COG4942    182 E---LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1362-2066 1.23e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1362 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLqqeqiqeleq 1441
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKN---------- 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1442 crsvlehlpmavqeREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEE 1521
Cdd:TIGR04523  115 --------------DKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1522 SHRKVEGQQKVItelegqrELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQK 1601
Cdd:TIGR04523  181 EKLNIQKNIDKI-------KNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1602 QKEQLTQDLERKGQELvlqKERIQVLEDQRTLqTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsL 1681
Cdd:TIGR04523  254 QLNQLKDEQNKIKKQL---SEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDW--------------------N 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1682 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQ 1761
Cdd:TIGR04523  310 KELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1762 LEEAQRaLAQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 1841
Cdd:TIGR04523  383 KQEIKN-LESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1842 LEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAE 1921
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1922 ALQEALSKAQATLQEKEQRLleqaelsctleastatlqatldtcqaraRQLEEALRVREGEIQTQALQHQeaMQHLQQEL 2001
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKI----------------------------SDLEDELNKDDFELKKENLEKE--IDEKNKEI 570

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517 2002 CQKEEDlrqqdeqrqllekavaQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI 2066
Cdd:TIGR04523  571 EELKQT----------------QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1204-1651 1.24e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1204 KLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLqrqLSQSQEEKSKWEGKQNSLESELRDLHETMASLQ 1283
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL---KDEQNKIKKQLSEKQKELEQNNKKIKELEKQLN 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1284 SRlrQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQ 1363
Cdd:TIGR04523  292 QL--KSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1364 EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCR 1443
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1444 SVLEhlpMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESH 1523
Cdd:TIGR04523  450 SVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1524 RKVEgqqKVITELEGQ-----RELQRVALTHLTLDLEERSQELQTQSSQLHE----LENHSTRLAKELQERDQEVMSQRQ 1594
Cdd:TIGR04523  527 EKLE---SEKKEKESKisdleDELNKDDFELKKENLEKEIDEKNKEIEELKQtqksLKKKQEEKQELIDQKEKEKKDLIK 603

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1595 QIEELQKQKEQLTQDLERKGQElvlqKERIQVLEDQRTLQTKILEEDLEQIKHSLRE 1651
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 896-1138 1.25e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  896 LLETLLQTQKELADASQQLERLRQDMKvQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLT 975
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  976 SQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASltlSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQ 1055
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPE---DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1056 RELGVQVELLRQEVKEKEadfvareaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQA 1135
Cdd:COG4942    167 AELEAERAELEALLAELE--------EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ...
gi 1958767517 1136 QAQ 1138
Cdd:COG4942    239 AAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 296-1125 1.28e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  296 RNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQ------ 369
Cdd:TIGR02169  207 REKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlge 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  370 ----DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALagqtvdlQGEVDSLSKerellqtargelqqql 445
Cdd:TIGR02169  287 eeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL-------LAEIEELER---------------- 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  446 evlEQEAWRLRRVNVELQLQGDSAQGEKLEQqeelhlavrereRLQEtlvgLEAKQSESLSELIALREALESsrlagelL 525
Cdd:TIGR02169  344 ---EIEEERKRRDKLTEEYAELKEELEDLRA------------ELEE----VDKEFAETRDELKDYREKLEK-------L 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  526 KQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALdkvalnqqllqleqenqsmcsRVEAAEQL 605
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL---------------------EIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  606 RSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAER 685
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGER 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  686 QEEAL-ARAGQEKEALVRERAALEVRLQAVERDRQD-----------LAEQVLGLRSAKEQLEGNL-----FEAQQQNSV 748
Cdd:TIGR02169  537 YATAIeVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAvdlveFDPKYEPAF 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  749 IQVTKSQLEVQiqtIIQAKEVIQGEVKCLKLELDT-ERSHAEQ--ERDAVARQLAQAEQEGQaalerqkvahEEEVNRLQ 825
Cdd:TIGR02169  617 KYVFGDTLVVE---DIEAARRLMGKYRMVTLEGELfEKSGAMTggSRAPRGGILFSRSEPAE----------LQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  826 EKWEKERALLQQKLDKtletLERERTELEMKLREQHTETEALRAQREEertqadsalYQMQLETEKERVSLLETLLQ-TQ 904
Cdd:TIGR02169  684 EGLKRELSSLQSELRR----IENRLDELSQELSDASRKIGEIEKEIEQ---------LEQEEEKLKERLEELEEDLSsLE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  905 KELADASQQLERLR---QDMKVQKLKEQETTGMLQAQLRGAQ-QELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVT 980
Cdd:TIGR02169  751 QEIENVKSELKELEariEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  981 HNDS-QRLVKQEIEEKVREAQECSRIQkELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELG 1059
Cdd:TIGR02169  831 LEKEiQELQEQRIDLKEQIKSIEKEIE-NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1060 VQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVraslwAQEAKAAQLQLQLRSTEAQLEAL 1125
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIP-----EEELSLEDVQAELQRVEEEIRAL 970
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1351-2035 1.61e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.35  E-value: 1.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1351 EIESERERAQALQEQGELKVAQGKALQENLT-LLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREV 1429
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEkELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1430 DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1509
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1510 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEV 1589
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1590 MSQR---------QQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQW 1660
Cdd:TIGR00618  435 LQQRyaelcaaaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1661 QLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER--IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1738
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkqRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1739 TLQQRLQEAKEQGELREQVLQGQLEEAQRALAqrDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEl 1818
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPEQD--LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1819 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQE 1898
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA----AREDALNQSLKE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1899 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRV 1978
Cdd:TIGR00618  748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767517 1979 REGEIQTQALQHQEAMQH-LQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQ 2035
Cdd:TIGR00618  828 QEEEQFLSRLEEKSATLGeITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
PRK11281 PRK11281
mechanosensitive channel MscK;
1738-2060 1.73e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.30  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1738 ATLQQRLQEAKEQGELREQ--VLQGQLEEAQRALAQRD---HELEALRQEQQQTRGQEESMKQKTSALQAALEQ------ 1806
Cdd:PRK11281    39 ADVQAQLDALNKQKLLEAEdkLVQQDLEQTLALLDKIDrqkEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEetretl 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1807 AHVTLKERQGELEEHRGQVQRLQEELIVEGRQV--------RA-------------LEEVLGDLRAESREHEKTVLALQQ 1865
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLvslqtqpeRAqaalyansqrlqqIRNLLKGGKVGGKALRPSQRVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1866 rcAEQA--------QEHEAEARTLQDSWLQAQ-----ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQ 1931
Cdd:PRK11281   199 --AEQAllnaqndlQRKSLEGNTQLQDLLQKQrdyltARIQRLEHQLQLLQEAiNSKRLTLSEKTVQEAQSQDEAARIQA 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1932 ATLQEKE--------QRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEI--------QTQALQHQEAMQ 1995
Cdd:PRK11281   277 NPLVAQEleinlqlsQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLKGSLllsrilyqQQQALPSADLIE 356

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767517 1996 HL----------QQELCQKEEDLRQQDEqrqLLEKAVAQRSQENGIQEKQSLEQEKEEEtRGLLESL-KEL--QLTVA 2060
Cdd:PRK11281   357 GLadriadlrleQFEINQQRDALFQPDA---YIDKLEAGHKSEVTDEVRDALLQLLDER-RELLDQLnKQLnnQLNLA 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 665-893 1.77e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  665 AHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQ 744
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  745 QnsvIQVTKSQLEVQIQTIIQakeviQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRL 824
Cdd:COG4942     98 E---LEAQKEELAELLRALYR-----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767517  825 QEKWEKERALL--QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKER 893
Cdd:COG4942    170 EAERAELEALLaeLEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
393-932 2.47e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  393 EEEGKALRERLQKLTGERDalagqtvDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQlqgdsaqge 472
Cdd:PRK02224   198 EKEEKDLHERLNGLESELA-------ELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIE--------- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  473 klEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENS 552
Cdd:PRK02224   262 --DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  553 LKAEVADLRAAAVKLGALNEALaldkvalnqqllqlEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLET 632
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEEL--------------REEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  633 QLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQ-----QLHQDAERQE--EALARAGQEKEALVRERA 705
Cdd:PRK02224   406 DLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEGSPhvETIEEDRERVEELEAELE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  706 ALEVR-------------LQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT---IIQAKEV 769
Cdd:PRK02224   486 DLEEEveeveerleraedLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEkreAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  770 IQGEVKCLKLELDTERSHAEQERDAVAR---QLAQAEQEGQAALE-RQKVAHEEEVN-----RLQEKWEKERALLQQKLD 840
Cdd:PRK02224   566 EAEEAREEVAELNSKLAELKERIESLERirtLLAAIADAEDEIERlREKREALAELNderreRLAEKRERKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  841 KTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQ-LETEKERVSLLETLLQTQKELADASQQLE---- 915
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEeLEELRERREALENRVEALEALYDEAEELEsmyg 725

                          570
                   ....*....|....*..
gi 1958767517  916 RLRQDMKVQKLKEQETT 932
Cdd:PRK02224   726 DLRAELRQRNVETLERM 742
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 393-715 2.55e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  393 EEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGE 472
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  473 KLEQQEELHLAVRERERLQETLVgleakqseslseliALREALES--SRLAGELLKQ---EQEEVAAALARAEQSIVELS 547
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLH--------------KLEEALNDleARLSHSRIPEiqaELSKLEEEVSRIEARLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  548 SSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEaaeqlrsALQVDLAEAERSREALWEEK 627
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE-------ELEAALRDLESRLGDLKKER 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  628 THLETQLRKAEETGAELQAELRGAREEKEElkeklneahhQQEAATAQLQQLHQ--DAERQEEALARAGQEKEALVRERA 705
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKRLSE----------LKAKLEALEEELSEieDPKGEDEEIPEEELSLEDVQAELQ 961

                          330
                   ....*....|
gi 1958767517  706 ALEVRLQAVE 715
Cdd:TIGR02169  962 RVEEEIRALE 971
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1727-1970 2.76e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1727 SLLLTHREQETATLQQRLQEAKEQGELREQVL---QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAA 1803
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELaalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1804 LEQAHVTLKERQGELEEHRGQVQRLQE----ELIVEGRQVRALEEVLGDLRAESREhektvlalQQRCAEQAQEHEAEAR 1879
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPA--------RREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1880 TLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQ 1959
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243

                          250
                   ....*....|.
gi 1958767517 1960 ATLDTCQARAR 1970
Cdd:COG4942    244 PAAGFAALKGK 254
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1537-2022 2.91e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1537 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKG-- 1614
Cdd:COG4913    259 ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgd 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1615 --QELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKE 1692
Cdd:COG4913    339 rlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1693 KEVECQQERIQELQEHMGQLEQQLQGLhRKVGETSLLLTHREQ-------ETATLQQRLQEAKEqGELREQ-----VLQG 1760
Cdd:COG4913    419 RELRELEAEIASLERRKSNIPARLLAL-RDALAEALGLDEAELpfvgeliEVRPEEERWRGAIE-RVLGGFaltllVPPE 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRD-------HELEALRQEQQQTRGQEES----MKQKTSALQAALEQ-----AHVTLKERQGELEEHR-- 1822
Cdd:COG4913    497 HYAAALRWVNRLHlrgrlvyERVRTGLPDPERPRLDPDSlagkLDFKPHPFRAWLEAelgrrFDYVCVDSPEELRRHPra 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1823 ----GQV------------QRLQEELIV---EGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQD 1883
Cdd:COG4913    577 itraGQVkgngtrhekddrRRIRSRYVLgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY 656

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1884 SW-----LQAQATLAEQEQELEALRAENqysrqqeeaafGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 1958
Cdd:COG4913    657 SWdeidvASAEREIAELEAELERLDASS-----------DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 1959 QATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAV 2022
Cdd:COG4913    726 EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1591-2074 3.14e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 3.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1591 SQRQQIEELQKQKEQLTQDLERKGQELvlqKERIQVLEDQrtlqTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDG 1670
Cdd:TIGR00618  191 SLHGKAELLTLRSQLLTLCTPCMPDTY---HERKQVLEKE----LKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1671 KSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQ 1750
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1751 GELREQVLQGQLEeaqraLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQE 1830
Cdd:TIGR00618  344 RRLLQTLHSQEIH-----IRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1831 ELIVEGRQVRA-LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 1909
Cdd:TIGR00618  419 FRDLQGQLAHAkKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1910 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 1989
Cdd:TIGR00618  499 LQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQC 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1990 HQEA-------MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQK 2062
Cdd:TIGR00618  579 DNRSkedipnlQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE 658

                          490
                   ....*....|..
gi 1958767517 2063 EEEILMLREAQQ 2074
Cdd:TIGR00618  659 RVREHALSIRVL 670
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1698-2173 3.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1698 QQERIQELQEHMGQLEQQLQGLHRKVGETSL-LLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHE- 1775
Cdd:COG4913    260 LAERYAAARERLAELEYLRAALRLWFAQRRLeLLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDr 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1776 LEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR----ALEEVLGDLRA 1851
Cdd:COG4913    340 LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1852 ESREHEKTVLALQQR--------------CAEQAQEHEAEA---------RTLQDSWLQA-------QAT--LAEQEQEL 1899
Cdd:COG4913    420 ELRELEAEIASLERRksniparllalrdaLAEALGLDEAELpfvgelievRPEEERWRGAiervlggFALtlLVPPEHYA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1900 EALRAENQYSRQQ----EEAAFGQAEALQEALSKAqaTLQEK------------EQRLLEQAELSC--TLEASTATLQAT 1961
Cdd:COG4913    500 AALRWVNRLHLRGrlvyERVRTGLPDPERPRLDPD--SLAGKldfkphpfrawlEAELGRRFDYVCvdSPEELRRHPRAI 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1962 LDTCQAR-----------------------ARQLEEALRVREGEIQTQALQHQEAMQHLQQElcqkeedLRQQDEQRQLL 2018
Cdd:COG4913    578 TRAGQVKgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAE-------LDALQERREAL 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2019 EKAVAQRSQENGIQEKQSLEQEKEEETRGLLES---LKELQLTVAQKEEEILMLREAQQRQNQEASSpshrsfpaekpsl 2095
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELERLDASsddLAALEEQLEELEAELEELEEELDELKGEIGR------------- 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767517 2096 QLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQA 2173
Cdd:COG4913    718 LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1725-1974 3.31e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 3.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1725 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 1804
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1805 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 1882
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1883 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 1962
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767517 1963 DTCQARARQLEE 1974
Cdd:NF012221  1765 AQADAKGAKQDE 1776
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1675-2080 3.66e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1675 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEAKEQGELR 1754
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1755 EQvLQGQLEEAQRALAQRDHEL-EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELI 1833
Cdd:COG4717    159 RE-LEEELEELEAELAELQEELeELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1834 VEgRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 1909
Cdd:COG4717    238 AA-ALEERLKEARLLLLIAAALLALLGLGGSLLSLILtiagVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1910 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 1989
Cdd:COG4717    317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELL----REAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1990 HQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 2069
Cdd:COG4717    393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

                          410
                   ....*....|.
gi 1958767517 2070 REAQQRQNQEA 2080
Cdd:COG4717    473 ELLQELEELKA 483
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 936-1140 3.68e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  936 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1015
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1016 LTLSLVE---------KEKRLLVLQEADSVRQreLVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEE 1086
Cdd:COG4942    102 QKEELAEllralyrlgRQPPLALLLSPEDFLD--AVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 1087 LEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLR 1140
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-1014 3.81e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  788 AEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKldKTLETLERERTELEMKLREQHTETEAL 867
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA--RRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  868 RAQREEERTQADSALYQMQLETEKERVslleTLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELK 947
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPL----ALLLSPEDFLDAVRRLQYLKYLAPARR-EQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517  948 EAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKA 1014
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 597-828 5.07e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 5.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  597 SRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQL 676
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  677 QQLHQDAERQEEALARAGQEKEALV----RERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVT 752
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517  753 KSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKW 828
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
364-723 5.20e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 5.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  364 RQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQ 443
Cdd:PRK02224   249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  444 QLEVLEQEAWRLRRvnvelqlQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGE 523
Cdd:PRK02224   329 RLEECRVAAQAHNE-------EAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  524 LLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAE 603
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  604 QLRSALQVDLAEAERSREALwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDA 683
Cdd:PRK02224   482 AELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1958767517  684 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAE 723
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA 600
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1550-1799 7.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1550 LTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLED 1629
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1630 QRtlqtKILEEDLEQIKHSLRERgqeLASQWQLMQERAED----GKSPSKAQRgSLEHLKLILRDKEKEVECQQERIQEL 1705
Cdd:COG4942     91 EI----AELRAELEAQKEELAEL---LRALYRLGRQPPLAlllsPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1706 QEHMGQLEQQLQGLHRKvgetslllthrEQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQ 1785
Cdd:COG4942    163 AALRAELEAERAELEAL-----------LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                          250
                   ....*....|....
gi 1958767517 1786 TRGQEESMKQKTSA 1799
Cdd:COG4942    232 LEAEAAAAAERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
670-919 8.37e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 8.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  670 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQnsvi 749
Cdd:COG4913    224 FEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  750 qvtksQLEVQIQTIIQAKEviqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWe 829
Cdd:COG4913    299 -----ELRAELARLEAELE-----------RLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR- 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  830 kerallqQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQmqletekervsLLETLLQTQKELAD 909
Cdd:COG4913    362 -------ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE-----------AEAALRDLRRELRE 423

                          250
                   ....*....|
gi 1958767517  910 ASQQLERLRQ 919
Cdd:COG4913    424 LEAEIASLER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1651-1876 8.46e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 8.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1651 ERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 1730
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1731 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVT 1810
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1811 LKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEA 1876
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1443-1832 1.12e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 47.51  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1443 RSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQrGQIQDLKKQLGTLECLALELEES 1522
Cdd:pfam10174  136 RKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAE-MQLGHLEVLLDQKEKENIHLREE 214

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1523 -HRKVEGQQ-----KVITELEGQRELQRVALTHLTLDLEERSQELQTQS-----------SQLHELENHSTRLAKELQER 1585
Cdd:pfam10174  215 lHRRNQLQPdpaktKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllhtedreeeiKQMEVYKSHSKFMKNKIDQL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1586 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVlEDQRTlqtKILEEDLEQIKHSLRERGQELASQWQLMQE 1665
Cdd:pfam10174  295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTA-KEQRA---AILQTEVDALRLRLEEKESFLNKKTKQLQD 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1666 RAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQ 1745
Cdd:pfam10174  371 LTEE----KSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALS 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1746 EA-------KEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEL 1818
Cdd:pfam10174  447 EKeriierlKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAV 526

                          410
                   ....*....|....
gi 1958767517 1819 EEHRGQVQRLQEEL 1832
Cdd:pfam10174  527 EQKKEECSKLENQL 540
PRK11281 PRK11281
mechanosensitive channel MscK;
1869-2260 1.15e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1869 EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEaLQEALSKAQATLQEKEQRLLEQAELS 1948
Cdd:PRK11281    73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQ-LESRLAQTLDQLQNAQNDLAEYNSQL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1949 CTLEASTATLQATLDTCQARARQLEEALRvregeiqtQALQHQEAMQHLQQELCQKEEDL--RQQDEQRQLLEkavaqrs 2026
Cdd:PRK11281   152 VSLQTQPERAQAALYANSQRLQQIRNLLK--------GGKVGGKALRPSQRVLLQAEQALlnAQNDLQRKSLE------- 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2027 qenGIQEKQSLEQEKEEetrglleslkELQLTVAQKEEEILMLREAQQRQNQEASspshrsfpaEKPSLQLLLAQQDLER 2106
Cdd:PRK11281   217 ---GNTQLQDLLQKQRD----------YLTARIQRLEHQLQLLQEAINSKRLTLS---------EKTVQEAQSQDEAARI 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2107 LQNALRQTEAreiewrekAQGLALS--LAQSKASISSL--QEIAMflqASVLERESEQQR--------LQEELVLSRQAL 2174
Cdd:PRK11281   275 QANPLVAQEL--------EINLQLSqrLLKATEKLNTLtqQNLRV---KNWLDRLTQSERnikeqisvLKGSLLLSRILY 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2175 EEQQSRgphsssradqgPKAGQDTEPGEVIeAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQchNAQLRTTLEQVE 2254
Cdd:PRK11281   344 QQQQAL-----------PSADLIEGLADRI-ADLRLEQFEINQQRDALFQPDAYIDKLEAGHKSEV--TDEVRDALLQLL 409


                   ....*.
gi 1958767517 2255 RERRKL 2260
Cdd:PRK11281   410 DERREL 415
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
684-1142 1.20e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  684 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEgnlfEAQQQNSVIQVTKSQLEVQIQti 763
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELE----ELEAELEELREELEKLEKLLQ-- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  764 iqakeviqgevkclKLELDTERSHAEQERDAVARQLAQAEQEGQ--AALERQKVAHEEEVNRLQEKWEKERALLQQKLDK 841
Cdd:COG4717    127 --------------LLPLYQELEALEAELAELPERLEELEERLEelRELEEELEELEAELAELQEELEELLEQLSLATEE 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  842 TLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDM 921
Cdd:COG4717    193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLI 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  922 KVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIdlqkQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1001
Cdd:COG4717    273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL----EEEELEELLAALGLPPDLSPEELLELLDRIEE 348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1002 CSRIQKELEKEKASLTLSLVEKEKRLLvLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAR-E 1080
Cdd:COG4717    349 LQELLREAEELEEELQLEELEQEIAAL-LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALdE 427

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 1081 AQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQpENQAQAQLRSL 1142
Cdd:COG4717    428 EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQE-LEELKAELREL 488
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 844-1475 1.39e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  844 ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLEtllQTQKELADASQQLERLRQDMKV 923
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAE---EMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  924 QKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK---DKIDLQKQVEDLTSQLVTHNDSQ-------RLVKQEIE 993
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLLEDQNsklskerKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  994 EKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKE 1073
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1074 ADFVAREAQLLEELEASRIAERQVRaslwaqEAKAAQLQLQlrsteaqlEALVAEQQPENQAQAQLRSLYSVLQQAlgsa 1153
Cdd:pfam01576  243 EELQAALARLEEETAQKNNALKKIR------ELEAQISELQ--------EDLESERAARNKAEKQRRDLGEELEAL---- 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1154 cerRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQdlwkaqQARDDLRDQVQKLVQRLTDT 1233
Cdd:pfam01576  305 ---KTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHT------QALEELTEQLEQAKRNKANL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1234 EAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLhetmaslQSRLRQAELQKMEAQNDRELLQASKEKLSAQ 1313
Cdd:pfam01576  376 EKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-------QARLSESERQRAELAEKLSKLQSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1314 VEHLQacvtearaqaSAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1393
Cdd:pfam01576  449 LNEAE----------GKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQ 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1394 VETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELEND 1473
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSN 598


                   ..
gi 1958767517 1474 RE 1475
Cdd:pfam01576  599 LE 600
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1543-2270 1.52e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1543 QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ------ERDQEVMSQRQQIEELQKQKEQLTQDLERKGQE 1616
Cdd:COG3096    290 LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQaasdhlNLVQTALRQQEKIERYQEDLEELTERLEEQEEV 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1617 LVLQKERIQVLEDQRTLQtkilEEDLEQIKHSLRERGQEL------ASQWQLMQERAEDGKSPSKAQRGSLEHLK---LI 1687
Cdd:COG3096    370 VEEAAEQLAEAEARLEAA----EEEVDSLKSQLADYQQALdvqqtrAIQYQQAVQALEKARALCGLPDLTPENAEdylAA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1688 LRDKEKEVECQ----QERIQELQEHMGQLEQQLQGLHRKVGETSlllthREQETATLQQRLQEAKEQGEL--REQVLQGQ 1761
Cdd:COG3096    446 FRAKEQQATEEvlelEQKLSVADAARRQFEKAYELVCKIAGEVE-----RSQAWQTARELLRRYRSQQALaqRLQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1762 LEEAQRALAQRdHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 1841
Cdd:COG3096    521 LAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAA 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1842 LEEVLgdlraesrehektvLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAafgQAE 1921
Cdd:COG3096    600 RAPAW--------------LAAQDA-LERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES---QIE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1922 ALQEALSKAQATLQEKEQR----LLEQAELSCTLE-----------ASTATLQATLDTCQARARQLE---EALRVREGEI 1983
Cdd:COG3096    662 RLSQPGGAEDPRLLALAERlggvLLSEIYDDVTLEdapyfsalygpARHAIVVPDLSAVKEQLAGLEdcpEDLYLIEGDP 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1984 QTQALQHQEAmQHLQQELCQKEEDL--------------RQQDEQRqlLEKAVAQRSQENGIQEKQSLEQEKEEETRGLL 2049
Cdd:COG3096    742 DSFDDSVFDA-EELEDAVVVKLSDRqwrysrfpevplfgRAAREKR--LEELRAERDELAEQYAKASFDVQKLQRLHQAF 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2050 ESLKELQLTVAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllaqqdlerLQNALRQTEAREIEWREKAqgla 2129
Cdd:COG3096    819 SQFVGGHLAVAFAPDPEAELAALRQRRSE----------------------------LERELAQHRAQEQQLRQQL---- 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2130 lslAQSKASISSLQeiAMFLQASVLERESEQQR---LQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEA 2206
Cdd:COG3096    867 ---DQLKEQLQLLN--KLLPQANLLADETLADRleeLREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQA 941

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 2207 EPSPGVGEKEQLRQRLERLQQAVAELE----VDRSKLQCHNA----QLRTTLEQVERERRKLkRDSLRASRA 2270
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFALSEVVQRRPhfsyEDAVGLLGENSdlneKLRARLEQAEEARREA-REQLRQAQA 1012
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1247-1868 1.66e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1247 LQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQkmeAQNDRELLQASKEKLSAQVEHL-QACVTEAR 1325
Cdd:pfam05483  160 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQ---AENARLEMHFKLKEDHEKIQHLeEEYKKEIN 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1326 AQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKvaqgkalQENLTLLAQTLSNREREVETLQAEVQELE 1405
Cdd:pfam05483  237 DKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQ-------DENLKELIEKKDHLTKELEDIKMSLQRSM 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1406 KQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRS-VLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQ 1484
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSfVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKK 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1485 LLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVE--------------GQQKVITELEGQRELQRVALTHL 1550
Cdd:pfam05483  390 SSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEelkgkeqelifllqAREKEIHDLEIQLTAIKTSEEHY 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1551 TLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVmsqRQQIEELQKQKEQLTQDlERKGQELVLQKERIQVLEDQ 1630
Cdd:pfam05483  470 LKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEA---SDMTLELKKHQEDIINC-KKQEERMLKQIENLEEKEMN 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1631 rtlqtkiLEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMG 1710
Cdd:pfam05483  546 -------LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENK 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1711 QLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEA----KEQGELREQVLQGQLEEAQRALAQRDhelEALRQEQQQT 1786
Cdd:pfam05483  619 ALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIAD---EAVKLQKEID 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1787 RGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR---LQEELIVEGRQVRA-LEEVLGDLRAESREHEKTVLA 1862
Cdd:pfam05483  696 KRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEqssAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKME 775


                   ....*.
gi 1958767517 1863 LQQRCA 1868
Cdd:pfam05483  776 AKENTA 781
mukB PRK04863
chromosome partition protein MukB;
612-1357 1.71e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  612 DLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLqQLHQDAERQEEALA 691
Cdd:PRK04863   273 DYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  692 RAGQEKEALVrerAALEVRLQAVErdrqDLAEQVLGLRSAKEQLEGNLFEAQ------QQNSVIQVTKSqleVQIQTIIQ 765
Cdd:PRK04863   352 RYQADLEELE---ERLEEQNEVVE----EADEQQEENEARAEAAEEEVDELKsqladyQQALDVQQTRA---IQYQQAVQ 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  766 AKEVIQGEVKCLKLELD------TERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE------EEVNRlQEKWEKERA 833
Cdd:PRK04863   422 ALERAKQLCGLPDLTADnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiaGEVSR-SEAWDVARE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  834 LL-----QQKLDKTLETLERERTELEMKLREQHTETEALR--AQREEERTQADSALYQMQLETEKERVSLLETLLQTQKE 906
Cdd:PRK04863   501 LLrrlreQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAefCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARER 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  907 LADASQQLERLRQDmkVQKLKEQETTgMLQAQLRGAQ------------QELKEAIQQHRDDLAAFQKDKIDLQKQVEDL 974
Cdd:PRK04863   581 RMALRQQLEQLQAR--IQRLAARAPA-WLAAQDALARlreqsgeefedsQDVTEYMQQLLERERELTVERDELAARKQAL 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  975 TSQLvthndsQRLVKQEIEEKVREAQECSRIQKEL--------EKEKASLTLSLVEKEKRLLVLQEADSVRQR------- 1039
Cdd:PRK04863   658 DEEI------ERLSQPGGSEDPRLNALAERFGGVLlseiyddvSLEDAPYFSALYGPARHAIVVPDLSDAAEQlagledc 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1040 ---------ELVSLRQDIQEAQEGQRELGVQ-------------VELLRQEVKEKEADFVAREAQLLEELEASRIAERQ- 1096
Cdd:PRK04863   732 pedlyliegDPDSFDDSVFSVEELEKAVVVKiadrqwrysrfpeVPLFGRAAREKRIEQLRAEREELAERYATLSFDVQk 811

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1097 -------------VRASLWAQ---EAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSA------- 1153
Cdd:PRK04863   812 lqrlhqafsrfigSHLAVAFEadpEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnlladet 891

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1154 -CERRPELRGGGDSVPTPwGSDPDQNGAsRLLKRGPLLTALSAEAVALALqkLHQDLWKAQQARDDLRDQV---QKLVQR 1229
Cdd:PRK04863   892 lADRVEEIREQLDEAEEA-KRFVQQHGN-ALAQLEPIVSVLQSDPEQFEQ--LKQDYQQAQQTQRDAKQQAfalTEVVQR 967

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1230 LTDTEAQKSQ----VHSELQD-LQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELL- 1303
Cdd:PRK04863   968 RAHFSYEDAAemlaKNSDLNEkLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLg 1047

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 1304 ----QASKEKLSAQVEHLQACVTEARAQASAA----GVLEEDLRTARSALKLKNEEIESERE 1357
Cdd:PRK04863  1048 vpadSGAEERARARRDELHARLSANRSRRNQLekqlTFCEAEMDNLTKKLRKLERDYHEMRE 1109
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1736-2093 1.80e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1736 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLK-ER 1814
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmER 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1815 QGELEEHRgqvqrlQEELIVEGRQVRalEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeARTLQDSWLQAQATLAE 1894
Cdd:pfam17380  347 ERELERIR------QEERKRELERIR--QEEIAMEISRMRELERLQMERQQKNERVRQELEA-ARKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1895 QEQELEALRAEnqysrqQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEE 1974
Cdd:pfam17380  418 QKVEMEQIRAE------QEEARQREVRRLEEERAREMERVRLEEQERQQQVE---------------------RLRQQEE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1975 ALRVREGEIQTQALQHQEAMQH----LQQELCQKEEDLRQQDEQRQLLEKAVAQRsQENGIQEKQSLEQEKEEETRGLLE 2050
Cdd:pfam17380  471 ERKRKKLELEKEKRDRKRAEEQrrkiLEKELEERKQAMIEEERKRKLLEKEMEER-QKAIYEEERRREAEEERRKQQEME 549

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1958767517 2051 SLKELQLTVAQKEEEI----LMLREAQQRQNQEASSPSHRSFPAEKP 2093
Cdd:pfam17380  550 ERRRIQEQMRKATEERsrleAMEREREMMRQIVESEKARAEYEATTP 596
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1453-2177 2.16e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1453 VQEREQKLSVQRDQIRELEndREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV 1532
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLA--RQFALCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEH 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1533 -ITELEGQRELQRVAltHLTLDLEERSQELQTQSSQLH----ELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQ-- 1605
Cdd:pfam12128  226 wIRDIQAIAGIMKIR--PEFTKLQQEFNTLESAELRLShlhfGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEkr 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1606 --LTQDLERKGQELVLQKERIQVLEDQRTlqtKILEEDLEQIKHSLrERGQELASQWQLMQERAE---------DGKSPS 1674
Cdd:pfam12128  304 deLNGELSAADAAVAKDRSELEALEDQHG---AFLDADIETAAADQ-EQLPSWQSELENLEERLKaltgkhqdvTAKYNR 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1675 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthREQETATLQqRLQEAKEQGELR 1754
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL-------------REQLEAGKL-EFNEEEYRLKSR 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1755 EQVLQGQLEEAQRA------LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRL 1828
Cdd:pfam12128  446 LGELKLRLNQATATpelllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDEL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1829 QEELIVegrQVRALEEVLGDLRAESREHEKTVLALQQRCAEQaqeheaeartlqdswLQAQATLAEQEQELEALRAENQY 1908
Cdd:pfam12128  526 ELQLFP---QAGTLLHFLRKEAPDWEQSIGKVISPELLHRTD---------------LDPEVWDGSVGGELNLYGVKLDL 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1909 SRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL 1988
Cdd:pfam12128  588 KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1989 QHQEAMQHLQQelcQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEEETRGLLESLKELQLtvAQKEEEILM 2068
Cdd:pfam12128  668 KKNKALAERKD---SANERLNSLEAQLKQLDKKHQAWLEE--QKEQKREARTEKQAYWQVVEGALDAQL--ALLKAAIAA 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2069 LREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDL-ERLQNALRQTEAREIEWREKAQGLALSLAQSKasiSSLQEIAM 2147
Cdd:pfam12128  741 RRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREiRTLERKIERIAVRRQEVLRYFDWYQETWLQRR---PRLATQLS 817

                          730       740       750
                   ....*....|....*....|....*....|
gi 1958767517 2148 FLQASVLERESEQQRLQEELVLSRQALEEQ 2177
Cdd:pfam12128  818 NIERAISELQQQLARLIADTKLRRAKLEME 847
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1202-1509 2.32e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1202 LQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 1281
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1282 LQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNE----EIESERE 1357
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlsrSINKIKQ 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1358 RAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQEL-----EKQREMQKAALELLSLD--LKKRS--RE 1428
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekkEKESKISDLEDELNKDDfeLKKENleKE 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1429 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQ 1508
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   .
gi 1958767517 1509 L 1509
Cdd:TIGR04523  643 L 643
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
340-853 3.12e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  340 NDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLtgerDALAGQTVD 419
Cdd:PRK02224   187 GSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL----ETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  420 LQGEVDSLSKERELLQTARGELQQQLEVLEQEAwRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEA 499
Cdd:PRK02224   263 LRETIAETEREREELAEEVRDLRERLEELEEER-DDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  500 KQSESLSELIA-LREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDK 578
Cdd:PRK02224   342 EEAESLREDADdLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  579 VALNQQLLQLEQENQSMCSRVEAAEQLRSA----------------------------LQVDLAEAERSREAL------W 624
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetieedrerveeLEAELEDLEEEVEEVeerlerA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  625 EEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRER 704
Cdd:PRK02224   502 EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  705 AALEVRLQAVER------DRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQI--------QTIIQAKEVI 770
Cdd:PRK02224   582 AELKERIESLERirtllaAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdearieeaREDKERAEEY 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  771 QGEVKCLKLELDTERSHAEQERDAVARQLAQAE--QEGQAALERQKVAHE---EEVNRLQEKWEKERALLQQKLDKTLET 845
Cdd:PRK02224   662 LEQVEEKLDELREERDDLQAEIGAVENELEELEelRERREALENRVEALEalyDEAEELESMYGDLRAELRQRNVETLER 741


                   ....*...
gi 1958767517  846 LERERTEL 853
Cdd:PRK02224   742 MLNETFDL 749
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 210-457 3.39e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  210 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 289
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  290 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 369
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  370 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 449
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767517  450 QEAWRLRR 457
Cdd:COG4942    234 AEAAAAAE 241
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
1702-2152 4.21e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 45.67  E-value: 4.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1702 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ 1781
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1782 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVL 1861
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1862 ALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRL 1941
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAA 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1942 LEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKA 2021
Cdd:COG5278    318 AAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAA 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2022 VAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQ 2101
Cdd:COG5278    398 AAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAAL 477

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 2102 QDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAS 2152
Cdd:COG5278    478 AAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASA 528
PRK11281 PRK11281
mechanosensitive channel MscK;
1184-1413 4.71e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.67  E-value: 4.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1184 LKRGPLLTALSAEAValalqklhQDLWKAQ---QARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQL-SQSQEEKS 1259
Cdd:PRK11281    48 LNKQKLLEAEDKLVQ--------QDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNdEETRETLS 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1260 KWEGKQnsLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASkekLSAQVEHLQACVTEARAQASAAGVLEEDLR 1339
Cdd:PRK11281   120 TLSLRQ--LESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAA---LYANSQRLQQIRNLLKGGKVGGKALRPSQR 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1340 TARSA-LKLKNEEIESERERAQA-------LQEQGELKVAQGKALQENLTLLaQTLSNREREVETlQAEVQELEKQREMQ 1411
Cdd:PRK11281   195 VLLQAeQALLNAQNDLQRKSLEGntqlqdlLQKQRDYLTARIQRLEHQLQLL-QEAINSKRLTLS-EKTVQEAQSQDEAA 272


                   ..
gi 1958767517 1412 KA 1413
Cdd:PRK11281   273 RI 274
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
948-1161 4.84e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  948 EAIQQHRDDLAAFQKDKIDLQKQVEDLTsQLVTHNdsqrlvkQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRL 1027
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLE-PIRELA-------ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1028 LvlqeadsvrQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADfvaREAQLLEELEASRIAERQVRASLWAQEAK 1107
Cdd:COG4913    300 L---------RAELARLEAELERLEARLDALREELDELEAQIRGNGGD---RLEQLEREIERLERELEERERRRARLEAL 367

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 1108 AAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQALGSACERRPELR 1161
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLR 418
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1712-2081 4.93e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.27  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1712 LEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1791
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1792 SMKQKTSALQAALEQAHVTLKE--------------RQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHE 1857
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIREleediktltqrvleRETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1858 KTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATL 1934
Cdd:pfam07888  192 KEFQELRNSLAQrdtQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1935 QEKEQRLLEQAELSCTLEastatlQATLDTCQARARQLEEalrvREGEIQTQALQHqEAMQHLQQELCQKEEDLRQQDEQ 2014
Cdd:pfam07888  272 AELHQARLQAAQLTLQLA------DASLALREGRARWAQE----RETLQQSAEADK-DRIEKLSAELQRLEERLQEERME 340

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 2015 RQLLEKAVAQRSQENGIQEKQSlEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEAS 2081
Cdd:pfam07888  341 REKLEVELGREKDCNRVQLSES-RRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
502-1094 5.45e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 5.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  502 SESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVal 581
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  582 nqqllqleqenqsmcsRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETG--AELQAELRGAREEKEELK 659
Cdd:PRK03918   246 ----------------ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekAEEYIKLSEFYEEYLDEL 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  660 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEqvlgLRSAKEQLEGNl 739
Cdd:PRK03918   310 REIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE----LERLKKRLTGL- 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  740 feaqqqnsviqvTKSQLEVQIQTIIQAKEVIQGEVKCLKLELdtershaeqerdavaRQLAQAEQEGQAALERQKVAHEE 819
Cdd:PRK03918   385 ------------TPEKLEKELEELEKAKEEIEEEISKITARI---------------GELKKEIKELKKAIEELKKAKGK 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  820 EVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREqhteteaLRAQREEertqadsalyqmqLETEKERVSLLET 899
Cdd:PRK03918   438 CPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK-------LRKELRE-------------LEKVLKKESELIK 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  900 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEAIQQhrddLAAFQKDKIDLQKQVEDLTSQLV 979
Cdd:PRK03918   498 LKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK----LEELKKKLAELEKKLDELEEELA 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  980 T-HNDSQRLVKQEIEEKVREAQECSRIQKELekekasltLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQREL 1058
Cdd:PRK03918   574 ElLKELEELGFESVEELEERLKELEPFYNEY--------LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEEL 645

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1958767517 1059 GVQVELLRQEVKEKEADFVAREAQLLEELEASRIAE 1094
Cdd:PRK03918   646 RKELEELEKKYSEEEYEELREEYLELSRELAGLRAE 681
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 811-1099 5.68e-04

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 44.52  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  811 ERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREE----ERTQADSALYQMQ 886
Cdd:pfam13868   32 KRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEeklqEREQMDEIVERIQ 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  887 LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE-------QETTGMLQAQLRGAQQELKEAIQQHRDDLAA 959
Cdd:pfam13868  112 EEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEderileyLKEKAEREEEREAEREEIEEEKEREIARLRA 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  960 FQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLlvLQEADSVRQR 1039
Cdd:pfam13868  192 QQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAERE--EEEFERMLRK 269

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1040 ELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRA 1099
Cdd:pfam13868  270 QAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRE 329
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1207-1502 6.39e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 6.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1207 QDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRL 1286
Cdd:COG4372     31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1287 RQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ-ALQEQ 1365
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAlDELLK 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1366 GELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSV 1445
Cdd:COG4372    191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVE 270

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1446 LEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQI 1502
Cdd:COG4372    271 KDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1884-2118 6.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1884 SWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEqaelsctLEASTATLQATLD 1963
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA-------LEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1964 TCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEE 2043
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQ--AEELRADLAELAA 164

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767517 2044 ETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEARE 2118
Cdd:COG4942    165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
46 PHA02562
endonuclease subunit; Provisional
 1556-1796 7.04e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 7.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1556 ERSQELQTQSSQLHELEnhstrlakelqerdQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQT 1635
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQ--------------QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDEL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1636 KILEEDLEQIKHSLRERGQELA---SQWQLMQERA----EDGKSPSKAQrgslehlklilrdkekEVECQQERIQELQEH 1708
Cdd:PHA02562   244 LNLVMDIEDPSAALNKLNTAAAkikSKIEQFQKVIkmyeKGGVCPTCTQ----------------QISEGPDRITKIKDK 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1709 MGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQEAKEQGELREQVLQG----------QLEEAQRALAQRDHELEA 1778
Cdd:PHA02562   308 LKELQHSLEKLDTAIDE----LEEIMDEFNEQSKKLLELKNKISTNKQSLITlvdkakkvkaAIEELQAEFVDNAEELAK 383

                          250
                   ....*....|....*...
gi 1958767517 1779 LRQEQQQTRGQEESMKQK 1796
Cdd:PHA02562   384 LQDELDKIVKTKSELVKE 401
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1452-1681 7.26e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 7.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1452 AVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 1531
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1532 VITELEGQRELQRVALThltldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLE 1611
Cdd:COG4942    111 RALYRLGRQPPLALLLS------PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767517 1612 RKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPS-KAQRGSL 1681
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGfAALKGKL 255
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
779-952 7.51e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 7.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  779 LELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLR 858
Cdd:COG3206    208 VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYT 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  859 EQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQK--LKEQETTGMLQ 936
Cdd:COG3206    288 PNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRrlEREVEVARELY 367

                          170
                   ....*....|....*.
gi 1958767517  937 AQLRGAQQELKEAIQQ 952
Cdd:COG3206    368 ESLLQRLEEARLAEAL 383
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1387-1941 7.53e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 7.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1387 LSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQ 1466
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1467 IRELENDREAQRTALEHQLLDLEQKAQVIESQrgqiqdLKKQLGTLECLALELEESHRKVEGQQKVITELEGQREL---- 1542
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKN------IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLleke 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1543 -------------QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 1609
Cdd:TIGR04523  182 klniqknidkiknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1610 LERKGQELvlqKERIQVLEDQRTLqTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsLEHLKLILR 1689
Cdd:TIGR04523  262 QNKIKKQL---SEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDW--------------------NKELKSELK 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1690 DKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRaL 1769
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKN-L 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1770 AQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDL 1849
Cdd:TIGR04523  390 ESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1850 RAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSK 1929
Cdd:TIGR04523  453 ELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          570
                   ....*....|..
gi 1958767517 1930 AQATLQEKEQRL 1941
Cdd:TIGR04523  529 LESEKKEKESKI 540
46 PHA02562
endonuclease subunit; Provisional
 810-1025 9.02e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 9.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  810 LERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEmKLREQHTETEalraQREEERTQADSALYQ--MQL 887
Cdd:PHA02562   193 IQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE-ELTDELLNLV----MDIEDPSAALNKLNTaaAKI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  888 ETEKERVSLLETLLQTQKELADASQQLERlrQDMKVQKLKEQETTGMLQ-AQLRGAQQELKEAIqqhrDDLAAFQKDKID 966
Cdd:PHA02562   268 KSKIEQFQKVIKMYEKGGVCPTCTQQISE--GPDRITKIKDKLKELQHSlEKLDTAIDELEEIM----DEFNEQSKKLLE 341

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767517  967 LQKQVEDLTSQLVTHNDSQRLVKQEIE----EKVREAQECSRIQKELEKEKAslTLSLVEKEK 1025
Cdd:PHA02562   342 LKNKISTNKQSLITLVDKAKKVKAAIEelqaEFVDNAEELAKLQDELDKIVK--TKSELVKEK 402
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1603-1905 1.02e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1603 KEQLTQDLER-KGQELVLQKERIQVLE------------DQRTLQTKILEEDLEQIKHSLRErgqelasqwQLMQERAED 1669
Cdd:PRK10929    25 EKQITQELEQaKAAKTPAQAEIVEALQsalnwleerkgsLERAKQYQQVIDNFPKLSAELRQ---------QLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1670 GKSPSKAQRGSLEHLKLI----LRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQ 1745
Cdd:PRK10929    96 RSVPPNMSTDALEQEILQvssqLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNE----IERRLQTLGTPNTPLA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1746 EAkeqgelreQVLQGQLEEAQRALAQRDHELEAL----RQEqqQTRGQEESMKQKTSALQAALEQAHVTLK-ERQGELEE 1820
Cdd:PRK10929   172 QA--------QLTALQAESAALKALVDELELAQLsannRQE--LARLRSELAKKRSQQLDAYLQALRNQLNsQRQREAER 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1821 HRGQVQRLQE------ELIVEgrQVRALEEVLGDLRAESREHEktVLALQQRcaeqaqehEAEARTLQDSwlQAQATLAE 1894
Cdd:PRK10929   242 ALESTELLAEqsgdlpKSIVA--QFKINRELSQALNQQAQRMD--LIASQQR--------QAASQTLQVR--QALNTLRE 307

                          330
                   ....*....|....*...
gi 1958767517 1895 QEQEL-------EALRAE 1905
Cdd:PRK10929   308 QSQWLgvsnalgEALRAQ 325
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1740-1984 1.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1740 LQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ--QTRGQEESMKQKTSALQAALEQAhvtlkerQGE 1817
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEA-------RAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1818 LEEHRGQVQRLQEELIVEGRQVRALEE--VLGDLRAEsrehektVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQ 1895
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQ-------LAELEAELAELSARYTPNHPDVI----ALRAQIAAL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1896 EQELEALRAENQYSRQQE-EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLdtcqARARQLEE 1974
Cdd:COG3206    304 RAQLQQEAQRILASLEAElEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL----QRLEEARL 379

                          250
                   ....*....|
gi 1958767517 1975 ALRVREGEIQ 1984
Cdd:COG3206    380 AEALTVGNVR 389
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1819-2027 1.24e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1819 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTL----QDSWLQAQATLAE 1894
Cdd:COG3914      1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAageaAAAAAALLLLAAL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1895 QEQELEALRAENQYsrQQEEAAFGQAEALQEALSKAQATL--QEKEQRLLEQAELSCT----LEASTATLQATLDTCQAR 1968
Cdd:COG3914     81 LELAALLLQALGRY--EEALALYRRALALNPDNAEALFNLgnLLLALGRLEEALAALRralaLNPDFAEAYLNLGEALRR 158

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 1969 ARQLEEALrvregEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQ 2027
Cdd:COG3914    159 LGRLEEAI-----AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 205-561 1.27e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  205 SEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNH 284
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  285 AELMEHEASLSRNAqEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQdpnkaLTLVHSVLTRR 364
Cdd:TIGR02169  751 QEIENVKSELKELE-ARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR-----LREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  365 QQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQ 444
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  445 LEVLEQEAWRLRrvnvELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSEsLSELIALREALESSRLAGEl 524
Cdd:TIGR02169  905 IEELEAQIEKKR----KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAE-LQRVEEEIRALEPVNMLAI- 978

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1958767517  525 lkQEQEEVAAALAraeqsivELSSSENSLKAEVADLR 561
Cdd:TIGR02169  979 --QEYEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
935-1153 2.04e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  935 LQAQLRGAQQELKEA---IQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEK 1011
Cdd:COG4372     43 LQEELEQLREELEQAreeLEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1012 EKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASR 1091
Cdd:COG4372    123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEEL 202

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767517 1092 IAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSA 1153
Cdd:COG4372    203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1344-2092 2.27e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 2.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1344 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVET---LQAEVQELEKQREMQKAAlELLSL 1420
Cdd:TIGR00606  170 ALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIrdqITSKEAQLESSREIVKSY-ENELD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1421 DLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQR--------DQIRELENDREAQRTALEHQLLDLEQKA 1492
Cdd:TIGR00606  249 PLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdEQLNDLYHNHQRTVREKERELVDCQREL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1493 QVIESQRGQIQDLKKQLgtleclalelEESHRKVEGQQKVITELEGQRELQRVAL-THLTLDLEERSQELQTQSSQLHEL 1571
Cdd:TIGR00606  329 EKLNKERRLLNQEKTEL----------LVEQGRLQLQADRHQEHIRARDSLIQSLaTRLELDGFERGPFSERQIKNFHTL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1572 -----ENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErkgqelvlqkeriqvledqrtLQTKILEEDLEQIK 1646
Cdd:TIGR00606  399 vierqEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE---------------------LKKEILEKKQEELK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1647 HSLRERGQELASQWQLMQERAEDGKspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGET 1726
Cdd:TIGR00606  458 FVIKELQQLEGSSDRILELDQELRK--AERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1727 SLLLTHREQETATLQQRLQEAKEQGELREQV---------------LQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1791
Cdd:TIGR00606  536 QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpnkkqledwlhsKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1792 SMKQKTSALQAAL------EQAHVTLKERQGELEEHRGQVQRLQ----------EELIVEGRQVRALEEVLGDLRAESRE 1855
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRAMLAgatavysqfiTQLTDENQSCCPVCQRVFQTEAELQE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1856 HEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKaQATLQ 1935
Cdd:TIGR00606  696 FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE-QETLL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1936 EKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL-QHQEAMQHLQQELCQKEEDLRQQDEQ 2014
Cdd:TIGR00606  775 GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVnQEKQEKQHELDTVVSKIELNRKLIQD 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2015 RQLLEKAVAQRSQENG-----IQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFP 2089
Cdd:TIGR00606  855 QQEQIQHLKSKTNELKseklqIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKET 934


                   ...
gi 1958767517 2090 AEK 2092
Cdd:TIGR00606  935 SNK 937
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 617-1508 2.82e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.04  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  617 ERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEelkeklneahhqqeaataqlqqlhqdaerqeeALARAGQE 696
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKK--------------------------------ALEYYQLK 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  697 KEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQqnsviqvtksQLEVQIQTIIQAKEVIQGEVKC 776
Cdd:pfam02463  217 EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE----------EKLAQVLKENKEEEKEKKLQEE 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  777 LKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMK 856
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  857 LREQHTETEALRAQREEERTQADSALYQMQLEtekervsLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQ 936
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELE-------LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  937 AQLRGAQQELKEAIQqhrDDLAAFQKDKIDLQKQVEDLTSqlvTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASL 1016
Cdd:pfam02463  440 ELKQGKLTEEKEELE---KQELKLLKDELELKKSEDLLKE---TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLL 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1017 TLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQ 1096
Cdd:pfam02463  514 ALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1097 VRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPD 1176
Cdd:pfam02463  594 IAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1177 QNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQvhsELQDLQRQLSQSQE 1256
Cdd:pfam02463  674 ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE---ELKLLKQKIDEEEE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1257 EKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLqacvtearaqaSAAGVLEE 1336
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK-----------EEAELLEE 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1337 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALE 1416
Cdd:pfam02463  820 EQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEK 899

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1417 LLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREqkLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIE 1496
Cdd:pfam02463  900 KELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL--LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNL 977

                          890
                   ....*....|..
gi 1958767517 1497 SQRGQIQDLKKQ 1508
Cdd:pfam02463  978 MAIEEFEEKEER 989
mukB PRK04863
chromosome partition protein MukB;
1690-1946 2.94e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1690 DKEKEVECQQERIQELQEHMGQLE--------------QQLQGLHRKVGETSLLlthreqETATLQQRLQEAKEQGELRE 1755
Cdd:PRK04863   834 DPEAELRQLNRRRVELERALADHEsqeqqqrsqleqakEGLSALNRLLPRLNLL------ADETLADRVEEIREQLDEAE 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1756 QVLQ---------GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE-QAHVTLKERQGELEEHRGQV 1825
Cdd:PRK04863   908 EAKRfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQrRAHFSYEDAAEMLAKNSDLN 987

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1826 QRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQ----EQELEA 1901
Cdd:PRK04863   988 EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERararRDELHA 1067

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1958767517 1902 LRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 1946
Cdd:PRK04863  1068 RLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1840-1942 3.16e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 3.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1840 RALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFgq 1919
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAA----ELEEKQQELEAQLEQLQEKAAETSQERKQKR-- 218

                           90       100
                   ....*....|....*....|...
gi 1958767517 1920 AEALQEALSKAQatLQEKEQRLL 1942
Cdd:PRK11448   219 KEITDQAAKRLE--LSEEETRIL 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1271-1782 3.69e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1271 ELRDLHETMASLQSRLRQaeLQKMEAQNDREllqaskEKLSAQVEHLQACVTEARAQASAagvleedlrtaRSALKLKNE 1350
Cdd:COG4913    236 DLERAHEALEDAREQIEL--LEPIRELAERY------AAARERLAELEYLRAALRLWFAQ-----------RRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1351 EIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVD 1430
Cdd:COG4913    297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLP 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1431 LQQEQIQELeqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQD-LKKQL 1509
Cdd:COG4913    377 ASAEEFAAL---RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDaLAEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1510 GTLECL----------ALELEESHRKVEG---------------QQKVI-----TELEGQRELQRVALTH---LTLDLEE 1556
Cdd:COG4913    454 GLDEAElpfvgelievRPEEERWRGAIERvlggfaltllvppehYAAALrwvnrLHLRGRLVYERVRTGLpdpERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1557 RS--QELQTQSSQLH--------------------ELENHSTRLAKELQERDQEVMSQ-----------------RQQIE 1597
Cdd:COG4913    534 DSlaGKLDFKPHPFRawleaelgrrfdyvcvdspeELRRHPRAITRAGQVKGNGTRHEkddrrrirsryvlgfdnRAKLA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1598 ELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqELAsQWQLMQERAEDGKSPSKAQ 1677
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA-ELEAELERLDASSDDLAAL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1678 RGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLthREQETATLQQRLQEAKEQGELRE-- 1755
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA--RLELRALLEERFAAALGDAVERElr 768

                          570       580
                   ....*....|....*....|....*..
gi 1958767517 1756 QVLQGQLEEAQRALAQRDHELEALRQE 1782
Cdd:COG4913    769 ENLEERIDALRARLNRAEEELERAMRA 795
MutS2 COG1193
dsDNA-specific endonuclease/ATPase MutS2 [Replication, recombination and repair];
808-948 3.80e-03

dsDNA-specific endonuclease/ATPase MutS2 [Replication, recombination and repair];


Pssm-ID: 440806 [Multi-domain]  Cd Length: 784  Bit Score: 42.44  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  808 AALERQKVAHEEEvnrlqekwekerallqqkldktLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQL 887
Cdd:COG1193    521 EELERERRELEEE----------------------REEAERLREELEKLREELEEKLEELEEEKEEILEKAREEAEEILR 578

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767517  888 ETEKErvslLETLLQTQKELADASQQLERLRQDMK--VQKLKEQETTGMLQAQLRGAQQELKE 948
Cdd:COG1193    579 EARKE----AEELIRELREAQAEEEELKEARKKLEelKQELEEKLEKPKKKAKPAKPPEELKV 637
46 PHA02562
endonuclease subunit; Provisional
 1219-1424 3.81e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1219 LRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSK-----WEGKQNSLESELRDLHETMASLQSRLRQAELQK 1293
Cdd:PHA02562   172 NKDKIRELNQQIQTLDMKIDHIQQQI-KTYNKNIEEQRKKNGeniarKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1294 MEAQNDRELLQASKEKLSAQVEHLQ-------------ACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ 1360
Cdd:PHA02562   251 EDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcpTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD 330

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517 1361 ALQEQgelkVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKK 1424
Cdd:PHA02562   331 EFNEQ----SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1029-1250 4.37e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1029 VLQEADSVRQ--RELVSLRQDIQEAQEgqrelgvQVELLRQ--EVKEKEADFVAREAQLLEELEASRIAERQVRASLWaq 1104
Cdd:COG4913    223 TFEAADALVEhfDDLERAHEALEDARE-------QIELLEPirELAERYAAARERLAELEYLRAALRLWFAQRRLELL-- 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1105 EAKAAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQALGSACER-RPELRGGGDSVPTpwgSDPDQNGASRL 1183
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLD---ALREELDELEAQIRGNGGDRLEQlEREIERLERELEE---RERRRARLEAL 367

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1184 LKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQ 1250
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
PRK12704 PRK12704
phosphodiesterase; Provisional
 983-1138 4.68e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  983 DSQRLVKQEIEEKVREAQ-ECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQ 1061
Cdd:PRK12704    46 EAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEK-------E 118

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1062 VELLRQEVKEKEADFVAREAQLLEELEasRIaerqvrASLWAQEAKAAQLQlQLRStEAQLEALVAEQQPENQAQAQ 1138
Cdd:PRK12704   119 LEQKQQELEKKEEELEELIEEQLQELE--RI------SGLTAEEAKEILLE-KVEE-EARHEAAVLIKEIEEEAKEE 185
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1202-1417 4.90e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1202 LQKLHQDLWKAQQARDDLRDQvqklvQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 1281
Cdd:COG3206    184 LPELRKELEEAEAALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1282 LQSRLRQAELQKMEAQNDRELLQASKeklSAQVEHLQacVTEARAQASAagvLEEDLRTARSALKlknEEIESERERAQA 1361
Cdd:COG3206    259 LLQSPVIQQLRAQLAELEAELAELSA---RYTPNHPD--VIALRAQIAA---LRAQLQQEAQRIL---ASLEAELEALQA 327

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1362 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEL 1417
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEAL 383
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1553-1656 5.12e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 5.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1553 DLEERSQELQTQSSQLHELENHSTRLAKELQErdqevmsqrqQIEELQKQKEQLTQDLERKGQELV--LQKERIQVLEDQ 1630
Cdd:PRK00409   524 SLEELERELEQKAEEAEALLKEAEKLKEELEE----------KKEKLQEEEDKLLEEAEKEAQQAIkeAKKEADEIIKEL 593

                           90       100       110
                   ....*....|....*....|....*....|
gi 1958767517 1631 RTLQ----TKILEEDLEQIKHSLRERGQEL 1656
Cdd:PRK00409   594 RQLQkggyASVKAHELIEARKRLNKANEKK 623
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1756-1987 5.27e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 5.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1756 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVE 1835
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1836 GRQVRALEEVLG-----------DLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRA 1904
Cdd:COG3883     99 GGSVSYLDVLLGsesfsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1905 ENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQ 1984
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ...
gi 1958767517 1985 TQA 1987
Cdd:COG3883    259 AGS 261
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1827-1973 5.40e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 5.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1827 RLQEELIVEGRQVRA------LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQEL- 1899
Cdd:COG1566     55 RVTEVLVKEGDRVKKgqvlarLDPTDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELe 134

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1900 --EALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELScTLEASTATLQATLDTCQARARQLE 1973
Cdd:COG1566    135 ryQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQLAQAQAGLREEEELA-AAQAQVAQAEAALAQAELNLARTT 209
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1761-2258 6.25e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1761 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlKERQGELEEHRGQVQRLQEELivegrqvR 1840
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK-----LEKLLQLLPLYQELEALEAEL-------A 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1841 ALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1920
Cdd:COG4717    143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1921 EALQEALSKAQATLQ-EKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQ 1999
Cdd:COG4717    223 EELEEELEQLENELEaAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2000 ELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEeetrglLESLKELQLTVAQKEEEILMLREAQQRQN-- 2077
Cdd:COG4717    303 EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDR------IEELQELLREAEELEEELQLEELEQEIAAll 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2078 QEASSPSHRSFpaEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASisslqeiamFLQASVLERE 2157
Cdd:COG4717    377 AEAGVEDEEEL--RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE---------ELEEELEELE 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2158 SEQQRLQEELVLSRQALEEQQSRGphsssradqgpkagqdtepgevieaepspgvgEKEQLRQRLERLQQAVAELEVDRS 2237
Cdd:COG4717    446 EELEELREELAELEAELEQLEEDG--------------------------------ELAELLQELEELKAELRELAEEWA 493

                          490       500
                   ....*....|....*....|.
gi 1958767517 2238 KLQCHNAQLRTTLEQVERERR 2258
Cdd:COG4717    494 ALKLALELLEEAREEYREERL 514
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1721-1905 6.67e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 6.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1721 RKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSAL 1800
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1801 QAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE-QAQEHEAEAR 1879
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKElEEQLESLQEE 165

                          170       180
                   ....*....|....*....|....*.
gi 1958767517 1880 TLQDSWLQAQATLAEQEQELEALRAE 1905
Cdd:COG4372    166 LAALEQELQALSEAEAEQALDELLKE 191
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1243-1998 6.92e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 6.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1243 ELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVT 1322
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1323 EARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 1402
Cdd:pfam01576   86 EEEERSQQ---LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1403 ELEKQ-REMQKAALELLSLDLKKRSREVDlqqeqiqeleqcrsvlehlpmaVQEREQKLSVQRDQIRELENDREAQRTAL 1481
Cdd:pfam01576  163 EFTSNlAEEEEKAKSLSKLKNKHEAMISD----------------------LEERLKKEEKGRQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1482 EHQLLDLEQKAQVIESQRGQIQD-LKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQE 1560
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEeLQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEE 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1561 LQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKgqelvlQKERIQVLEDQRTlQTKILEE 1640
Cdd:pfam01576  301 LEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQK------HTQALEELTEQLE-QAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1641 DLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVecqqeriQELQEHMGQLEQQLQGLH 1720
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR-------AELAEKLSKLQSELESVS 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1721 RKVGETSLLLTHREQETATLQQRLQEAKEqgelreqvlqgQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSAL 1800
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQE-----------LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNV 515

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1801 QAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEaRT 1880
Cdd:pfam01576  516 ERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ-RQ 594

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1881 LQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELsctLEASTATLQA 1960
Cdd:pfam01576  595 LVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQ---LRAEMEDLVS 671

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1958767517 1961 TLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQ 1998
Cdd:pfam01576  672 SKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQ 709
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1699-2078 7.13e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.71  E-value: 7.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1699 QERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQV--LQGQ--------------- 1761
Cdd:PRK10246   432 HGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIkdLEAQraqlqagqpcplcgs 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1762 -------------LEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQGELEEHRGQVQRL 1828
Cdd:PRK10246   512 tshpaveayqalePGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQ---LQRDESEAQSLRQEEQALTQQWQAVCASL 588

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1829 QEELivegrqvrALEEVLGDLRAESREHEKTVLALQQRCAEQAQ--EHEAEARTLQDSWLQAQATLAEQEQELEALRAEN 1906
Cdd:PRK10246   589 NITL--------QPQDDIQPWLDAQEEHERQLRLLSQRHELQGQiaAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQE 660

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1907 qysrQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQ 1986
Cdd:PRK10246   661 ----DEEASWLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQCLSLHSQLQTL 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1987 ALQHQEAMQHLQQELCQKEEDLRQQ--DEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE 2064
Cdd:PRK10246   737 QQQDVLEAQRLQKAQAQFDTALQASvfDDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPD 816

                          410
                   ....*....|....
gi 1958767517 2065 EILMLREAQQRQNQ 2078
Cdd:PRK10246   817 GLDLTVTVEQIQQE 830
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1759-2014 7.19e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.71  E-value: 7.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1759 QGQLEEAQRALAQRDHELEALRQEQQQtrgqEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLqeELIVEGRQ 1838
Cdd:PRK10246   218 VQSLTASLQVLTDEEKQLLTAQQQQQQ----SLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAAL--SLAQPARQ 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1839 VRALEEvlgdlraESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEE- 1914
Cdd:PRK10246   292 LRPHWE-------RIQEQSAALAHTRQQIEEvntRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1915 -----AAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 1989
Cdd:PRK10246   365 lagwrAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQ 444

                          250       260
                   ....*....|....*....|....*
gi 1958767517 1990 HQEAMQHLQQELCQKEEDLRQQDEQ 2014
Cdd:PRK10246   445 LQVAIQNVTQEQTQRNAALNEMRQR 469
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1914-2262 7.61e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1914 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 1993
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1994 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2072
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2073 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2149
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2150 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2229
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767517 2230 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2262
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1554-1914 8.43e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.03  E-value: 8.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1554 LEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL--------VLQKERIQ 1625
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYkelsasseELSEEKDA 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1626 VLEDQRTLQTKILEedLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQEL 1705
Cdd:pfam07888  120 LLAQRAAHEARIRE--LEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQEL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1706 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEqgelreqvLQGQLEEAQRALAQRDHELEALrqEQQQ 1785
Cdd:pfam07888  198 RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRS--------LQERLNASERKVEGLGEELSSM--AAQR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1786 TRGQEESMKQKTSALQAALEQAHVTLKERQG------ELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAEsREHEKT 1859
Cdd:pfam07888  268 DRTQAELHQARLQAAQLTLQLADASLALREGrarwaqERETLQQSAEADKDRIEKLSAELQRLEERLQEERME-REKLEV 346

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1860 VLALQQRCAE-QAQEHEAEARTLQDSWLQAQatlAEQEQELEALRAENQYSRQQEE 1914
Cdd:pfam07888  347 ELGREKDCNRvQLSESRRELQELKASLRVAQ---KEKEQLQAEKQELLEYIRQLEQ 399
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
1730-2180 8.77e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 41.05  E-value: 8.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1730 LTHREQETATLQQRLQEAKE--QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQA 1807
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSltADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1808 HVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQ 1887
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1888 AQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQAtldtcQA 1967
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAA-----AA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1968 RARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRG 2047
Cdd:COG5278    313 AAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEV 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 2048 LLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQG 2127
Cdd:COG5278    393 LAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVA 472

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767517 2128 LALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 2180
Cdd:COG5278    473 ALAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAAL 525
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 637-866 9.06e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 9.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  637 AEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVER 716
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  717 D----RQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKclklELDTERSHAEQER 792
Cdd:COG4942     98 EleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA----ELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767517  793 DAVARQLAQAEQEgQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTlETLERERTELEMKLREQHTETEA 866
Cdd:COG4942    174 AELEALLAELEEE-RAALEALKAERQKLLARLEKELAELAAELAELQQEA-EELEALIARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1699-1935 9.25e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1699 QERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEakeqgelreqvLQGQLEEAQRALAQRDHELEA 1778
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGLVDL-----SEEAKLLLQQLSE-----------LESQLAEARAELAEAEARLAA 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1779 LRQEQQQTRGQeesmkqktsalqAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 1858
Cdd:COG3206    245 LRAQLGSGPDA------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767517 1859 TVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQ 1935
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1882-2084 9.30e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 9.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1882 QDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQAT 1961
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1962 LDTCQARARQL----------------------EEALRVRE--GEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQ--R 2015
Cdd:COG4942     99 LEAQKEELAELlralyrlgrqpplalllspedfLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAEleA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 2016 QLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPS 2084
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
597-708 9.49e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 41.38  E-value: 9.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517  597 SRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQL 676
Cdd:COG5283     14 SALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQAGIDTRQLSAAQRRLRSSL 93

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1958767517  677 QQLHQDAERQEEALARAGQEKEALVRERAALE 708
Cdd:COG5283     94 EQTNRQLERQQQRLARLGARQDRLKAARARLQ 125
PRK09039 PRK09039
peptidoglycan -binding protein;
1809-1944 9.58e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1809 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartlqdswlqA 1888
Cdd:PRK09039    46 REISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAA-----------A 114

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767517 1889 QATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQ 1944
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRES 170
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1838-2062 9.80e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 9.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1838 QVRALEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAF 1917
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767517 1918 GQAEALQEALSKAQATLQEKEQR----LLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEA 1993
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767517 1994 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngiQEKQSLEQEKEEETRGLLESLKELQLTVAQK 2062
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAEL---AAELAELQQEAEELEALIARLEAEAAAAAER 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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