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Conserved domains on  [gi|1958767515|ref|XP_038962798|]
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centrosome-associated protein CEP250 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-212 5.40e-44

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 159.05  E-value: 5.40e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  103 EEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRMEQEFFKGYLRGEHGRLLSVWRE 182
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767515  183 VVTFRRHFLKMKSATDRDLTELKAEHARLS 212
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1558-2111 1.39e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.39e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1558 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1637
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1717
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1797
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1877
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1878 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1957
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1958 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2037
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 2038 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2111
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 455-1036 9.99e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 9.99e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  455 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 534
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  535 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 614
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  615 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 694
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  695 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 774
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  775 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 851
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  852 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 926
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  927 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 1006
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767515 1007 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1036
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 844-1544 5.62e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 5.62e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  844 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 917
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  918 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 997
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  998 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1078 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1150
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1151 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1185
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1186 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1265
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1266 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1345
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1346 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1425
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1426 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1505
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767515 1506 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1544
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-492 3.08e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  245 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 324
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  325 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 404
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  405 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 484
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767515  485 QEAWRLRR 492
Cdd:COG4942    234 AEAAAAAE 241
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1949-2297 7.73e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1949 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 2028
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2029 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2107
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2108 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2184
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2185 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2264
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767515 2265 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2297
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-212 5.40e-44

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 159.05  E-value: 5.40e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  103 EEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRMEQEFFKGYLRGEHGRLLSVWRE 182
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767515  183 VVTFRRHFLKMKSATDRDLTELKAEHARLS 212
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1558-2111 1.39e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.39e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1558 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1637
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1717
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1797
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1877
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1878 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1957
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1958 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2037
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 2038 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2111
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 455-1036 9.99e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 9.99e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  455 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 534
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  535 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 614
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  615 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 694
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  695 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 774
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  775 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 851
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  852 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 926
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  927 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 1006
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767515 1007 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1036
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 844-1544 5.62e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 5.62e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  844 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 917
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  918 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 997
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  998 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1078 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1150
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1151 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1185
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1186 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1265
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1266 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1345
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1346 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1425
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1426 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1505
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767515 1506 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1544
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1256-2059 1.19e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.19e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1256 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1335
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1336 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 1411
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1412 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1491
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1492 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 1558
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1559 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 1638
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1639 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 1718
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1719 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 1795
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1955
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 2034
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767515 2035 ELCQKEEDLrqqDEQRQLLEKAVAQ 2059
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 830-1444 2.34e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 2.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  830 VARQLAQAEQEGQAALERQKVAHEEEVNRLQekwekERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEE 909
Cdd:COG1196    198 LERQLEPLERQAEKAERYRELKEELKELEAE-----LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  910 RTQADsalyqmqletekervSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQaQLRGAQQELKEAIQQHR 989
Cdd:COG1196    273 RLELE---------------ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE-ELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  990 DDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAD 1069
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1070 SVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQ 1149
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1150 LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRgplltALS 1229
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1230 AEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSKWEGKQNSLESELRD 1309
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1310 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1389
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 1390 ERERAQALQEQGELKVAQGKALQENLTLLAqtlsnrerEVETLQAEVQELEKQRE 1444
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPP--------DLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 565-1372 2.09e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 2.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  565 EEVAAALARAEQSIVELSSSENSLKAEVAdlraAAVKLGALNEAL-ALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSA 643
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  644 LQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEE 723
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  724 ALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKE 803
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  804 viqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLER 883
Cdd:TIGR02168  418 -----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  884 ERTELEM---KLREQHTETEALRAQREEERTQADS-ALYQMQLETEKERVSLLETLLQ------TQKELADASQQLERLR 953
Cdd:TIGR02168  487 LQARLDSlerLQENLEGFSEGVKALLKNQSGLSGIlGVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  954 QDmKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDsqrlVKQEIEEKVRE 1033
Cdd:TIGR02168  567 QN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD----LDNALELAKKL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1034 AQECSRIQKELEKEKASLTLSLVEKEKRLLVLQeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVa 1113
Cdd:TIGR02168  642 RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-----RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1114 reaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRp 1193
Cdd:TIGR02168  716 ---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI- 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1194 elrgggdsvptpwgsdpdQNGASRLLKRGPLLTALSAEAVAL--ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQ 1271
Cdd:TIGR02168  792 ------------------EQLKEELKALREALDELRAELTLLneEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1272 KSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEH 1351
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820
                   ....*....|....*....|.
gi 1958767515 1352 LQACVTEARAQASAAGVLEED 1372
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLE 954
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1255-1820 9.23e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.31  E-value: 9.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1255 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 1334
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1335 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 1414
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1415 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 1494
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1495 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 1574
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1575 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 1654
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1655 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 1734
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1735 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 1814
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767515 1815 RQEQQQ 1820
Cdd:PRK02224   714 YDEAEE 719
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1372-1890 5.03e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 5.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1372 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 1444
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1445 M----QKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 1520
Cdd:PRK02224   290 EleeeRDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1521 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 1600
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1601 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 1666
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1667 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 1740
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1741 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 1819
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 1820 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 1890
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 811-1648 6.45e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  811 CLKLELDTERSHAEQERDAvARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEM 890
Cdd:pfam02463  191 DLEELKLQELKLKEQAKKA-LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQ 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  891 KLREQhteTEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGML 970
Cdd:pfam02463  270 VLKEN---KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  971 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1050
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1051 LTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER 1130
Cdd:pfam02463  427 EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1131 QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPElrgggdsvptpWGSDP 1210
Cdd:pfam02463  507 SGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL-----------TELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1211 DQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ 1290
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1291 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE 1370
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1371 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLlAQTLSNREREVETLQAEVQELEKQREMQKAAL 1450
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1451 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1530
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1531 ESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK-----VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHE 1605
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILlkyeeEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767515 1606 LENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1648
Cdd:pfam02463  975 VNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 398-1043 1.40e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  398 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARgELQ 477
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-EAK 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  478 QQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERErlqetlvGLEAKQSESLSELIALREALESSRLAG 557
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE-------AAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  558 ELLKQEQEEVAAALARAEQSIVELSSSENSLKAEvaDLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAA 637
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE--EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  638 EQLRSALQVDLAEAERSREAlwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQD 717
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKA--EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  718 AERQEEAlaRAGQEKEALVRERAALEVRLQAVERdrqdlAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT 797
Cdd:PTZ00121  1551 LKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  798 IIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE----EEVNRLQE---KWEKERALL 870
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaEEDEKKAAealKKEAEEAKK 1703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  871 QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSA---------LYQMQLETEKERVSLLETLLQTQKE 941
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdeeekkkIAHLKKEEEKKAEEIRKEKEAVIEE 1783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  942 LADASQQLERLRQDMKVQKLKE---------QETTGMLQAQLRGAQQELKEAI---QQHRDDLAAFQKDKIDlQKQVEDL 1009
Cdd:PTZ00121  1784 ELDEEDEKRRMEVDKKIKDIFDnfaniieggKEGNLVINDSKEMEDSAIKEVAdskNMQLEEADAFEKHKFN-KNNENGE 1862

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1958767515 1010 TSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1043
Cdd:PTZ00121  1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1482-2296 3.84e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 3.84e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1482 EHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtleclaleLEESHRKV 1561
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1562 EGQ-QKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHEL--------------------------ENHSTRLA 1614
Cdd:pfam15921  144 RNQlQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeeasgkkiyehdsmstmhfRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1615 KELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQ-KERIQVLEDQRTLQTKILEEDleqiKHSLRERGQELAS 1693
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEK----ASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1694 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1773
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1774 TLQQRLQEAKEQGELREQVLQGQLEEAQRaLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlkERQGEL 1853
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS------ECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1854 EEHRGQVQRLQEELivegrqvraleEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQE 1933
Cdd:pfam15921  447 ERQMAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1934 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQlEEALRV 2013
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT-AGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2014 REGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEkaVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLT 2093
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2094 VAQKEEEILMLREAQQRQNQEASSPSHrsfpaeKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKAS 2173
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTN------KLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ 742

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2174 ISSLQEIAMFLQASVLERESEQQRLQEElvlsRQALEEQQSrgphsssradqgpkagqdtepgeVIEAEPSPGVGEKEQL 2253
Cdd:pfam15921  743 IDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELS-----------------------TVATEKNKMAGELEVL 795

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767515 2254 RQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLK 2296
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 786-1103 4.48e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 4.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  786 VTKSQLEVQIQTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVA----RQLAQAEQEGQAALERQKVAHEEEVNRLQ 860
Cdd:pfam17380  265 MTENEFLNQLLHIVQHQKAVSERQQQEKFEkMEQERLRQEKEEKAREverrRKLEEAEKARQAEMDRQAAIYAEQERMAM 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 EKWEKERALLQQKLDKTLETLERERTELEM-KLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslleTLLQTQ 939
Cdd:pfam17380  345 ERERELERIRQEERKRELERIRQEEIAMEIsRMRELERLQMERQQKNERVRQELEAARKVKILEEERQR-----KIQQQK 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  940 KELADASQQLERLRQDmKVQKLKEQETTGMlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDltsQLVTHNDS 1019
Cdd:pfam17380  420 VEMEQIRAEQEEARQR-EVRRLEEERAREM--ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD---RKRAEEQR 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1020 QRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVSLRQDIQEAQEGQRELGVQVEL 1099
Cdd:pfam17380  494 RKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER---RKQQEMEERRRIQEQMRKATEERSRLEA 570


                   ....
gi 1958767515 1100 LRQE 1103
Cdd:pfam17380  571 MERE 574
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1760-2009 3.37e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 3.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1760 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 1839
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1840 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 1917
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1918 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 1997
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767515 1998 DTCQARARQLEE 2009
Cdd:NF012221  1765 AQADAKGAKQDE 1776
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-492 3.08e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  245 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 324
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  325 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 404
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  405 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 484
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767515  485 QEAWRLRR 492
Cdd:COG4942    234 AEAAAAAE 241
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-658 1.00e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515   46 EAQKRQATLVRKLQA--KVLQYRSWCQDLEKRLEatgglipqRWESVEEpNLEQLLIRLEEEQQRCESLVEVNTELRLHM 123
Cdd:COG1196    206 ERQAEKAERYRELKEelKELEAELLLLKLRELEA--------ELEELEA-ELEELEAELEELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  124 EKADVVNKALQEDVEKLTVDWSRARDELMRKESQwrmeqeffkgylrgehgrllsvwrevvtfRRHFLKMKSATDRDLTE 203
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEER-----------------------------RRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  204 LKAEHARLSGSLLTCCLRLTLRAQSRDSSGSGRSDESEpaQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDR 283
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  284 VTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALASVEEEDTVTQT 363
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  364 PGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEA------MSFLQQQHNQWEEEGKALRER 437
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAaleaalAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  438 LQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGekleqqeELHL 517
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA-------ALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  518 AVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRA 597
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515  598 AAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREAL 658
Cdd:COG1196    719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 240-596 1.29e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  240 SEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNH 319
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  320 AELMEHEASLSRNAqEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQdpnkaLTLVHSVLTRR 399
Cdd:TIGR02169  751 QEIENVKSELKELE-ARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR-----LREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  400 QQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQ 479
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  480 LEVLEQEAWRLRrvnvELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSEsLSELIALREALESSRLAGEl 559
Cdd:TIGR02169  905 IEELEAQIEKKR----KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAE-LQRVEEEIRALEPVNMLAI- 978

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1958767515  560 lkQEQEEVAAALAraeqsivELSSSENSLKAEVADLR 596
Cdd:TIGR02169  979 --QEYEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1949-2297 7.73e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1949 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 2028
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2029 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2107
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2108 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2184
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2185 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2264
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767515 2265 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2297
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
38-212 5.40e-44

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 159.05  E-value: 5.40e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515   38 WRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA---------------TGGLIPQRWESVEEPNLEQLLIRL 102
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEktselektelllrklTLEPRLQRLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  103 EEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRMEQEFFKGYLRGEHGRLLSVWRE 182
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1958767515  183 VVTFRRHFLKMKSATDRDLTELKAEHARLS 212
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1558-2111 1.39e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.39e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1558 HRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1637
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqelasqwqlmqeraedgkspSKAQRGSLE 1717
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL---------------------LEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQgQL 1797
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-LE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1877
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1878 EEVLGDLRAESREHEKTVLALQQrcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEA 1957
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1958 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELC 2037
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 2038 QKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQ 2111
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 455-1036 9.99e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.48  E-value: 9.99e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  455 LQGEVDSLSKERELLQTARgELQQQLEVLEQEAWRLRRVNVELQLQgdsaqgeklEQQEELHLAVRERERLQETLVGLEA 534
Cdd:COG1196    198 LERQLEPLERQAEKAERYR-ELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  535 KQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKV 614
Cdd:COG1196    268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  615 ALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELK 694
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  695 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNL 774
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  775 FEAQQQNSVIQvtKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAA---LERQKVA 851
Cdd:COG1196    508 EGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  852 HEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALR-----AQREEERTQADSALYQMQLETEK 926
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtlAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  927 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQV 1006
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE-RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|
gi 1958767515 1007 EDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1036
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1726-2268 1.43e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.43e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1726 KEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAkeqgELREQVLQGQLEEAQRALA 1805
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1806 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLR 1885
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1886 AESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKA 1965
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEA----LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1966 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQkeEDLRQ 2045
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA--VLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2046 QDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE---EILMLREAQQRQNQEASSPSHRS 2122
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAalaAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2123 FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEEL 2202
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2203 VLSRQALEEQQSRGPHSSSRADQG----------------------PKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERL 2260
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERleeeleeealeeqleaereellEELLEEEELLEEEALEELPEPPDLEELERELERL 772


                   ....*...
gi 1958767515 2261 QQAVAELE 2268
Cdd:COG1196    773 EREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 437-954 2.91e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.91e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  437 RLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELH 516
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  517 LAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLR 596
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  597 AAAVK-------LGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQL 669
Cdd:COG1196    393 RAAAElaaqleeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  670 RKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAV 749
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  750 ERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTE---------- 819
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgrtlvaarl 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  820 ----RSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQ 895
Cdd:COG1196    633 eaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767515  896 HTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 954
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 844-1544 5.62e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 5.62e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  844 ALERQKVAHEEEVNRLQEKWEKERALLQqKLDKTLETLERERTELEMKLREQHTETEALRA------QREEERTQADSAL 917
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQ-ELEEKLEELRLEVSELEEEIEELQKELYALANeisrleQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  918 YQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK 997
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  998 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRiqKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELV 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1078 SLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER-----QVRASLWAQEAKAAQLQLQL-- 1150
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVDEGYEAAIEAALGGRLQAvv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1151 -RSTEAQLEA------------------LVAEQQPENQAQAQLRSLYSVLQQA--------------------------L 1185
Cdd:TIGR02168  552 vENLNAAKKAiaflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAkdlvkfdpklrkalsyllggvlvvddL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1186 GSACERRPELRGGGDSVPTpwgsDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1265
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTL----DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1266 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1345
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1346 SAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNR 1425
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1426 EREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIreL 1505
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--Q 942

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958767515 1506 ENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1544
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1256-2059 1.19e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.19e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1256 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1335
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1336 ELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----RAQALQEQGELKVAQGKAL 1411
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1412 QENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1491
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1492 EQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL---KKQLGTLECLALELEESH 1558
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1559 RKVEGQQKVITELEGQRELQRVALTHLTLDLeERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQK 1638
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDS-IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1639 EQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDgkspskaqrgsleh 1718
Cdd:TIGR02168  629 DDLDNALELAKKL--RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-------------- 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1719 lkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL-QEAKEQGELREQ--VLQG 1795
Cdd:TIGR02168  693 ----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaQLSKELTELEAEieELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1955
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQEKEQRLLEQAELSC-TLEASTATLQATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQ 2034
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLeEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAAIEEYEELKERYD 1003

                          810       820
                   ....*....|....*....|....*
gi 1958767515 2035 ELCQKEEDLrqqDEQRQLLEKAVAQ 2059
Cdd:TIGR02168 1004 FLTAQKEDL---TEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1734-2312 1.59e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 1.59e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1734 QERIQELQEHMGQLEQQLQGLHRkvgetslllthrEQETATLQQRLQEAKEQGELREQVL-----QGQLEEAQRALAQRD 1808
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER------------QAEKAERYRELKEELKELEAELLLLklrelEAELEELEAELEELE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1809 HELEALRQEQQQTRGQEESMKQKTSALQAALEqahvtlkERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAES 1888
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEELELELE-------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1889 REHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQAT 1968
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELE----EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1969 LQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEEALRVREGEIQTQALQHQEAMQHLQQELcqkEEDLRQQDE 2048
Cdd:COG1196    402 LEELEEAEEALLE---------------------RLERLEEELEELEEALAELEEEEEEEEEALEEAA---EEEAELEEE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2049 QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 2128
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2129 SLQLLLAQQDLERLQNALRQTEAREIEW-----REKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELV 2203
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVAAAAIEYlkaakAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2204 LSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRT 2283
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          570       580
                   ....*....|....*....|....*....
gi 1958767515 2284 TLEQVERERRKLKRDSLRASRAGSLEARE 2312
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEAL 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 830-1444 2.34e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 2.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  830 VARQLAQAEQEGQAALERQKVAHEEEVNRLQekwekERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEE 909
Cdd:COG1196    198 LERQLEPLERQAEKAERYRELKEELKELEAE-----LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  910 RTQADsalyqmqletekervSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQaQLRGAQQELKEAIQQHR 989
Cdd:COG1196    273 RLELE---------------ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE-ELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  990 DDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAD 1069
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1070 SVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQ 1149
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1150 LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRgplltALS 1229
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1230 AEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSKWEGKQNSLESELRD 1309
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1310 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1389
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 1390 ERERAQALQEQGELKVAQGKALQENLTLLAqtlsnrerEVETLQAEVQELEKQRE 1444
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPP--------DLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1246-1981 2.65e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 2.65e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1246 KAQQARDDLRD-QVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQA 1324
Cdd:TIGR02168  214 RYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1325 -------ELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERE----R 1393
Cdd:TIGR02168  294 aneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1394 AQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELekQREMQKAALELLSLDLKKRSREVDLQQEQIQE 1473
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL--QQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1474 LEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLE----------QKAQVIESQRGQIQDL--- 1540
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVLSELisv 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1541 KKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEeRSQELQTQSSQLHELENHSTRLAKELQER 1620
Cdd:TIGR02168  532 DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSI-KGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1621 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELvlQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQE 1700
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLDNALELAKKLR--PGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1701 RAEDgkspskaqrgslehlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRL- 1779
Cdd:TIGR02168  689 LEEK------------------IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIa 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1780 QEAKEQGELREQ--VLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtLKERQGELEEhr 1857
Cdd:TIGR02168  751 QLSKELTELEAEieELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAANLRE-- 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1858 gQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEAL 1937
Cdd:TIGR02168  825 -RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA----LLNERASLEEALALLRSELEEL 899

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958767515 1938 RAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 1981
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 386-952 3.98e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.98e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  386 NKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKE 465
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  466 RELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIA 545
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  546 LREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVAlnqqllqleq 625
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE---------- 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  626 enqsmcsRVEAAEQLRSALQVDLAEAERSREALWEEKtHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQE 705
Cdd:COG1196    468 -------LLEEAALLEAALAELLEELAEAAARLLLLL-EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  706 AATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQ 785
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  786 VTksqleVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEK 865
Cdd:COG1196    620 DT-----LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  866 ERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADsaLYQMQLETEKERVSLLETLLQTQKELADA 945
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE--EEELLEEEALEELPEPPDLEELERELERL 772


                   ....*..
gi 1958767515  946 SQQLERL 952
Cdd:COG1196    773 EREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1225-1828 6.03e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.62  E-value: 6.03e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1225 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLE 1304
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1305 SELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKN 1384
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1385 EEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsrev 1464
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE------------- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1465 dlqqeqiqeleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRgqiqDLKKQL 1544
Cdd:COG1196    446 ----------------------EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL----LLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1545 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQ-LHELENHSTRLAKELQERDQE 1623
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1624 VMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQrTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE 1703
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1704 DGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLqglhRKVGETSLLLTHREQETATLQQRLQEAK 1783
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----RELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958767515 1784 EQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESM 1828
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 796-1352 3.02e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.31  E-value: 3.02e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  796 QTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVARQLAQAE---QEGQAALERQKVAHEEEVNRLQEKWEKERALLQ 871
Cdd:COG1196    216 RELKEELKELEAELLLLKLReLEAELEELEAELEELEAELEELEaelAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  872 QkldktLETLERERTELEmkLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslLETLLQTQKELADASQQLER 951
Cdd:COG1196    296 E-----LARLEQDIARLE--ERRRELEERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  952 LRQDMKVQKLKEQETtgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKV 1031
Cdd:COG1196    366 ALLEAEAELAEAEEE----LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1032 REAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSL--RQDIQEAQEGQRELGVQVELLRQEVKEK-- 1107
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAaaRLLLLLEAEADYEGFLEGVKAALLLAGLrg 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1108 -------EADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSV 1180
Cdd:COG1196    522 lagavavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1181 LQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAV------ALALQKLHQDLWKAQQARDDL 1254
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEggsaggSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1255 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQND 1334
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*...
gi 1958767515 1335 RELLQASKEKLSAQVEHL 1352
Cdd:COG1196    762 LEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1499-2059 4.13e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 4.13e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1499 RDQIRELENDREAQRTALEHQ----LLDLEQKAQVIESQRGQIQDLKKQLGTLEclaleleeshRKVEGQQKVITELEGQ 1574
Cdd:COG1196    199 ERQLEPLERQAEKAERYRELKeelkELEAELLLLKLRELEAELEELEAELEELE----------AELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1575 RELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVL 1654
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1655 QKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEdgkspskaQRGSLEHLKLILRDKEKEVECQQ 1734
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--------LAAQLEELEEAEEALLERLERLE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1735 ERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 1814
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1815 RQEQQQTRGQEESMKQK--------------------------------------TSALQAALEQAHVTLKERQGELEEH 1856
Cdd:COG1196    501 ADYEGFLEGVKAALLLAglrglagavavligveaayeaaleaalaaalqnivvedDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1857 RGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQEL-- 1934
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAgg 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1935 ------EALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSctleastatlqatLDTCQARARQLE 2008
Cdd:COG1196    661 sltggsRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE-------------RLEEELEEEALE 727

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 2009 EALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 2059
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 871-1675 1.20e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 1.20e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  871 QQKLDKTLETLER---ERTELEM---KLREQHTETEALRAQREEERtQADSALYQMQLEtekervSLLETLLQTQKELAD 944
Cdd:TIGR02168  178 ERKLERTRENLDRledILNELERqlkSLERQAEKAERYKELKAELR-ELELALLVLRLE------ELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  945 ASQQLERLRQDMKVqKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVK 1024
Cdd:TIGR02168  251 AEEELEELTAELQE-LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1025 QEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEV 1104
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1105 KEKEADFVAREAQLLEELEASRIAERQ-VRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQ 1183
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1184 ALGSACERRPELRGGGDSVPTPWgsdpdQNGASRLLKRGPLLTALSAE-----AVALALQKLHQDLW--KAQQARDDLRD 1256
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALL-----KNQSGLSGILGVLSELISVDegyeaAIEAALGGRLQAVVveNLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1257 QVQKLVQRLTDTEAqKSQVHSELQDLQRQLSQSQEEkskWEGKQNSLESELRDLHETMASLQSRLRQAELQKmEAQNDRE 1336
Cdd:TIGR02168  565 LKQNELGRVTFLPL-DSIKGTEIQGNDREILKNIEG---FLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD-NALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1337 LLQASKEKLSAQVEHLQACVTEARAQASAAGV----------LEEDLRTARSALKLKNEEIESERERAQALQEQGELKVA 1406
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSilerrreieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1407 QGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKrsrevdlqqeQIQELEQCRSVLEHLPM 1486
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE----------AEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1487 AVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtleclaleleeshrkvEGQQK 1566
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI-----------------EELSE 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1567 VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLtqdle 1646
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL----- 927

                          810       820
                   ....*....|....*....|....*....
gi 1958767515 1647 rkgqelVLQKERIQVLEDQrtLQTKILEE 1675
Cdd:TIGR02168  928 ------ELRLEGLEVRIDN--LQERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1263-2078 1.60e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.60e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1263 QRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEgKQNSLESELRDLHETMA-----SLQSRLRQAELQKMEAQNDREL 1337
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLvlrleELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1338 LQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTL 1417
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSE----------LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1418 LAQTLSNREREVETLQAEVQELEKQREMQKAALEllsldlkkrsREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSV 1497
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELE----------ELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1498 QRDQIRELENdrEAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRkvegqqkvitELEGQREL 1577
Cdd:TIGR02168  398 LNNEIERLEA--RLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE----------RLEEALEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1578 QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLE-RKGQELVL-- 1654
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIEAALgg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1655 ------------QKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLI 1722
Cdd:TIGR02168  546 rlqavvvenlnaAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1723 LRDKEKEVECQQERIQELQEHMGQLEQQLQG----LHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQG--- 1795
Cdd:TIGR02168  626 LVVDDLDNALELAKKLRPGYRIVTLDGDLVRpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAElrk 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAESREHEKTVLALQqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1955
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELR----AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRvregEIQTQALQHQEAMQHLQQE 2035
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLELRLEGLEVR 937

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1958767515 2036 LCQKEEDLR--QQDEQRQLLEKAVAQRSQENGIQEKQ-SLEQEKEE 2078
Cdd:TIGR02168  938 IDNLQERLSeeYSLTLEEAEALENKIEDDEEEARRRLkRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 565-1372 2.09e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 2.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  565 EEVAAALARAEQSIVELSSSENSLKAEVAdlraAAVKLGALNEAL-ALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSA 643
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  644 LQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEE 723
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  724 ALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKE 803
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  804 viqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLER 883
Cdd:TIGR02168  418 -----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  884 ERTELEM---KLREQHTETEALRAQREEERTQADS-ALYQMQLETEKERVSLLETLLQ------TQKELADASQQLERLR 953
Cdd:TIGR02168  487 LQARLDSlerLQENLEGFSEGVKALLKNQSGLSGIlGVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  954 QDmKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDsqrlVKQEIEEKVRE 1033
Cdd:TIGR02168  567 QN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD----LDNALELAKKL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1034 AQECSRIQKELEKEKASLTLSLVEKEKRLLVLQeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVa 1113
Cdd:TIGR02168  642 RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-----RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1114 reaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRp 1193
Cdd:TIGR02168  716 ---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI- 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1194 elrgggdsvptpwgsdpdQNGASRLLKRGPLLTALSAEAVAL--ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQ 1271
Cdd:TIGR02168  792 ------------------EQLKEELKALREALDELRAELTLLneEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1272 KSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEH 1351
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820
                   ....*....|....*....|.
gi 1958767515 1352 LQACVTEARAQASAAGVLEED 1372
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLE 954
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1568-2302 2.18e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.18e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1568 ITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKE-------Q 1640
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrerlaN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1641 LTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKhSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLK 1720
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1721 LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETatlqqrLQEAKEQGELREQVLQGQLEEA 1800
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE------LEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1801 QRALAQRDHELEALRQEQQQTRGQEESMKQktsaLQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEV 1880
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLER----LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1881 LGdlraesrEHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQeqeleaLRAENQYSRQQEEAAFGQAEALQE 1960
Cdd:TIGR02168  543 LG-------GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE------IQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1961 ALSKAQATLQEKEQRLLeqaelsctleastatLQATLDTCQARARQLEEALRV---------REGEIQTQALQHQEAMQH 2031
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVL---------------VVDDLDNALELAKKLRPGYRIvtldgdlvrPGGVITGGSAKTNSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2032 LQQELCQKEEDLRQQDEQRQLLEKAVA-----QRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLRE 2106
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAelrkeLEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2107 AQQRQNQEASSpshrsfpaekpslqlllAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQA 2186
Cdd:TIGR02168  755 ELTELEAEIEE-----------------LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2187 SVLERESEQQRLQEELVLSRQALEEQQSRgphsssradqgpkAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAE 2266
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQ-------------IEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1958767515 2267 LEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRA 2302
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEEL 920
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 534-1160 2.37e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.23  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  534 AKQSESLSELIALREALEssRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDK 613
Cdd:COG1196    206 ERQAEKAERYRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  614 VALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEEL 693
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  694 KEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGN 773
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  774 LFEAQQQNSVIQVTKSQLEVQIQtiiqakeviqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE 853
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLA------------------ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  854 EEVNRLQEKWEKERALLQQKLDKTLETLERERTELEmklreqhTETEALRAQREEERTQADSALYQMQLETEKERVSLLE 933
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE-------AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  934 TLLQTQKELADAsqqlerlrqdmkvqklkeqettgmlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQL 1013
Cdd:COG1196    579 LDKIRARAALAA--------------------------ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1014 VTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQREL 1093
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1094 GVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEAL 1160
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1236-1971 1.54e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 1.54e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1236 ALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMA 1315
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1316 SLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvleedlrtarsalklkneEIESERERAQ 1395
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL-------------------EDRRERLQQE 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1396 ALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE 1475
Cdd:TIGR02168  423 IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1476 QCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQviESQRGQIQDLKKQLGTLECLALELE 1555
Cdd:TIGR02168  503 GFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL--NAAKKAIAFLKQNELGRVTFLPLDS 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1556 ESHRKVEGQQKVIteLEGQRELQRVALTHLTLDLEER------------SQELQTQSSQLHELENHST------------ 1611
Cdd:TIGR02168  581 IKGTEIQGNDREI--LKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvVDDLDNALELAKKLRPGYRivtldgdlvrpg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1612 -RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL-VLQKERIQVLEDQRTLQTKILEED-----LEQIKHSL 1684
Cdd:TIGR02168  659 gVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALaELRKELEELEEELEQLRKELEELSrqisaLRKDLARL 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1685 RERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLL 1764
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1765 LTHREQETATLQQRLQEAKEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHV 1844
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1845 TLKERQGELEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSW 1920
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRREL-------EELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDE 967

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767515 1921 LQAQATLAEQEQELEA-----LRAENQYSRQQEEAAF--GQAEALQEALSKAQATLQE 1971
Cdd:TIGR02168  968 EEARRRLKRLENKIKElgpvnLAAIEEYEELKERYDFltAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1310-2111 1.95e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.95e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1310 LHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIES 1389
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1390 ERERAQALQEQgelkvaqgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQE 1469
Cdd:TIGR02168  275 EVSELEEEIEE----------LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1470 QIQELEQCrsvLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALehqlLDLEQKAQVIESQRGQIQDLKKQLGTLEC 1549
Cdd:TIGR02168  345 KLEELKEE---LESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1550 LALELEESHRKvEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMS--- 1626
Cdd:TIGR02168  418 RLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSler 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1627 QRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIkhsLRERGQELASQWQLMQERAEDGK 1706
Cdd:TIGR02168  497 LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAV---VVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1707 SPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgeTSLLLTHREQETATLQQRLQEAKE-- 1784
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYri 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1785 ---QGEL--REQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQ 1859
Cdd:TIGR02168  648 vtlDGDLvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1860 VQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEA 1936
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1937 LRAEnqYSRQQEEAAfgqaeALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREG 2016
Cdd:TIGR02168  808 LRAE--LTLLNEEAA-----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2017 EIQtqalQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENG--IQEKQSLEQEKEEETRGLLESLKELQLTV 2094
Cdd:TIGR02168  881 ERA----SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAqlELRLEGLEVRIDNLQERLSEEYSLTLEEA 956

                          810
                   ....*....|....*..
gi 1958767515 2095 AQKEEEILMLREAQQRQ 2111
Cdd:TIGR02168  957 EALENKIEDDEEEARRR 973
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 432-1177 2.75e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.75e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  432 KALRERLQKLtgERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQ 511
Cdd:TIGR02168  216 KELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  512 QEELH-------LAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSS 584
Cdd:TIGR02168  294 ANEISrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  585 ENSLKAEVADLRAAAVKLgaLNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTH 664
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQL--ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  665 LETQLRKAEETGAELQAELRGAREEKEELKEKLNEAhHQQEAATAQLQQLHQDAERQEEALARAGQEKEAL--------- 735
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQL-QARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlselis 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  736 VRER------AALEVRLQAVERDRQDLAEQvlglrsakeqlegnLFEAQQQNSVIQVTKSQLEVQIQTIIQAK--EVIQG 807
Cdd:TIGR02168  531 VDEGyeaaieAALGGRLQAVVVENLNAAKK--------------AIAFLKQNELGRVTFLPLDSIKGTEIQGNdrEILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  808 EVKCLKLELDTErSHAEQERDAVARQLAQAE--QEGQAALERQKVAHEEEVNRLQE-----------KWEKERALLQQKL 874
Cdd:TIGR02168  597 IEGFLGVAKDLV-KFDPKLRKALSYLLGGVLvvDDLDNALELAKKLRPGYRIVTLDgdlvrpggvitGGSAKTNSSILER 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  875 DKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQlETEKERVSLLETLLQTQKELADASQQLERLRQ 954
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  955 DMKVQKLKEQETTGMLqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREA 1034
Cdd:TIGR02168  755 ELTELEAEIEELEERL-EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1035 QECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAr 1114
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE- 912

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767515 1115 eaqLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRStEAQLEALVAEQQP------ENQAQAQLRSL 1177
Cdd:TIGR02168  913 ---LRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALEnkieddEEEARRRLKRL 977
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1303-1867 6.43e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 6.43e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1303 LESELRDLHETMASLQSRLRQAELQKMEAQndRELLQASKEKLSAQVEHLQACVTEARAQASAAG----VLEEDLRTARS 1378
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELEELEleleEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1379 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLK 1458
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1459 KRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQ 1538
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1539 DLKKQLGTLECLALELEESHRKVEGQQkvitelegQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ 1618
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAEL--------LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1619 ERDQEVMSQRQQIEE-----LQKQKEQLTQDLERKGQELVLQKE-RIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELA 1692
Cdd:COG1196    528 VLIGVEAAYEAALEAalaaaLQNIVVEDDEVAAAAIEYLKAAKAgRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1693 SQWQLMQERAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLthREQET 1772
Cdd:COG1196    608 LREADARYYVLG----DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE--AEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1773 ATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGE 1852
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*
gi 1958767515 1853 LEEHRGQVQRLQEEL 1867
Cdd:COG1196    762 LEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 923-1693 1.24e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.57  E-value: 1.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  923 ETEKERVSLLETLLQTQKELADASQQLERL-RQDMKVQKLKEqettgmLQAQLRGAQQEL-KEAIQQHRDDLAAFQKDKI 1000
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLeRQAEKAERYKE------LKAELRELELALlVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1001 DLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLR 1080
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1081 QDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRAslwaQEAKAAQLQLQLRSTEAQLEAL 1160
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----LRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1161 VAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGdsvptpwgsdpdqngasrlLKRGPLLTALSAEAVALALQKL 1240
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE-------------------LEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1241 HQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVH-------------SELQDLQRQLSQSQEEKSKWE-GKQNSLESE 1306
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSELISVDEGYEaAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1307 LRDL----HETMASLQSRLRQAELQK-----MEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE------- 1370
Cdd:TIGR02168  547 LQAVvvenLNAAKKAIAFLKQNELGRvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvl 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1371 --EDLRTARSALKLKNEE-----IESERERAQALQEQGELKVAQG--------KALQENLTLLAQTLSNREREVETLQAE 1435
Cdd:TIGR02168  627 vvDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITGGSAKTNSSilerrreiEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1436 VQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTA 1515
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1516 LEHQLLDLEQKAQVIESQ----RGQIQDLKKQLGTLECLALEL-----------EESHRKVEGQQKVITELEGQRELQRV 1580
Cdd:TIGR02168  787 LEAQIEQLKEELKALREAldelRAELTLLNEEAANLRERLESLerriaaterrlEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1581 ALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQ 1660
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958767515 1661 V-----LEDQRTLQTKIlEEDLEQIKHSLRERGQELAS 1693
Cdd:TIGR02168  947 EeysltLEEAEALENKI-EDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1412-2211 1.68e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1412 QENLTLLAQTLSNREREVETLQAEVQELEKQREMQK----AALELLSLDLKKRSREVDLQQEQIQELeqcRSVLEHLPMA 1487
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQAEKAERYKELKAelreLELALLVLRLEELREELEELQEELKEA---EEELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1488 VQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtlECLALELEESHRKVEGQQKV 1567
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL---EELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1568 ITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLER 1647
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1648 KGQElvlqkeriqvledQRTLQTKILEEDLEQIKHSLRERGQELASQwqlmQERAEDGKSPSKAQRGSLEHLKLILRDKE 1727
Cdd:TIGR02168  419 LQQE-------------IEELLKKLEEAELKELQAELEELEEELEEL----QEELERLEEALEELREELEEAEQALDAAE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1728 KEVECQQERIQELQehmgQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLE--------- 1798
Cdd:TIGR02168  482 RELAQLQARLDSLE----RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvenlna 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1799 --EAQRALAQ--------------RDHELEALRQEQQQTRGQ--------EESMKQKTSALQAALEQAHV--TLKE--RQ 1850
Cdd:TIGR02168  558 akKAIAFLKQnelgrvtflpldsiKGTEIQGNDREILKNIEGflgvakdlVKFDPKLRKALSYLLGGVLVvdDLDNalEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1851 GELEEHRGQVQRLQEELI----VEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQA 1923
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAElekALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1924 QATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR 2003
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2004 ARQLEEALRVREGEIQTQALQHQEAMQHLQQElcqkeedLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGL 2083
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESL-------ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2084 LES-LKELQLTVAQKEEEILMLREAQQRQNQEasspshrsfpaekpslqLLLAQQDLERLQNALRQTEAREIEWREKAQG 2162
Cdd:TIGR02168  871 LESeLEALLNERASLEEALALLRSELEELSEE-----------------LRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2163 LALSLAQSKASISSLQEI-AMFLQASVLERESEQQRLQEELVLSRQALEE 2211
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1027-1867 2.29e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1027 IEEKVREAQECSRIQKEL-EKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQVELLRQEVK 1105
Cdd:TIGR02168  205 LERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1106 EKEADFVAREAQLLEELEASRIAERQVRAslwaQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 1185
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQI----LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1186 GSACERRPELRGggdsvptpwgsdpdqngasrllkrgplltalsaeavalALQKLHQDLWKAQQARDDLRDQVQKLVQRL 1265
Cdd:TIGR02168  354 ESLEAELEELEA--------------------------------------ELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1266 TDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQnsLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKL 1345
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1346 SAQVEHLQACVTEARAQASAAGVLEEDLRT---ARSALKLKNEEIESERERAQALQE-QGELKVAQGKALQENLTLLAqt 1421
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGfseGVKALLKNQSGLSGILGVLSELISvDEGYEAAIEAALGGRLQAVV-- 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1422 lsnrereVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQ 1501
Cdd:TIGR02168  552 -------VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1502 IRELENDREAQRTALEHQLLDL-------------------EQKAQVIESQRGQIQDLKKQLgtleclalelEESHRKVE 1562
Cdd:TIGR02168  625 VLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKI----------EELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1563 GQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLT 1642
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1643 QDLERKGQELVLQKERIQVLEDQRTLQTKILEEdLEQIKHSLRERGQELASQWQLMQERAEdgkspskaqrgslehlkli 1722
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAELTLLNEEAANLRERLESLERRIA------------------- 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1723 lrDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQ---GQLEE 1799
Cdd:TIGR02168  835 --ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELReleSKRSE 912

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767515 1800 AQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKE-RQGELEEHRGQVQRLQEEL 1867
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 243-771 3.27e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 3.27e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  243 AQLLLLVAKTQALEKEAHEKSQELMQLksqgDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAEL 322
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  323 MEHEASLSRNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQA 402
Cdd:COG1196    329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  403 VQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEV 482
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  483 LEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQ 562
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  563 EQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRS 642
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  643 ALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQE 722
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1958767515  723 EALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLE 771
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 255-952 3.47e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.47e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  255 LEKEAhEKSQELMQLKSQG-DLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMeheaSLSRNA 333
Cdd:TIGR02168  205 LERQA-EKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR----LEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  334 QEEKLSLQHVIKDITQALASVEEEDTVTQTpgSENSLQSDYNDLSQFDSQDPNKALTLVHSvLTRRQQAVQDLRQQLSGC 413
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRE--RLANLERQLEELEAQLEELESKLDELAEE-LAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  414 QEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRV 493
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  494 NVELQLQGDSAQGEKLEQ-----QEELHLAVRERERLQETLVGLEAKQSESLSELIAL---REALESSRLAGELLKQEQE 565
Cdd:TIGR02168  437 ELQAELEELEEELEELQEelerlEEALEELREELEEAEQALDAAERELAQLQARLDSLerlQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  566 EVAAALARAEQSI---------VELSSSENSLKAEVADLRAAAVKLGALNEA-------LALDKVALNQQLLQLEQENQS 629
Cdd:TIGR02168  517 GLSGILGVLSELIsvdegyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNelgrvtfLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  630 MC-------SRVEAAEQLRSALQ--------------------------------------------------------- 645
Cdd:TIGR02168  597 IEgflgvakDLVKFDPKLRKALSyllggvlvvddldnalelakklrpgyrivtldgdlvrpggvitggsaktnssilerr 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  646 VDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEAL 725
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  726 ARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQnsviqvtKSQLEVQIQTIIQAKEVI 805
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  806 QGEVKCLKLEL-DTERSHAEQERDAVARQLAQAE-QEGQAALERQKVAHEEEVNRLQEKWEKERALLQQkLDKTLETLER 883
Cdd:TIGR02168  830 ERRIAATERRLeDLEEQIEELSEDIESLAAEIEElEELIEELESELEALLNERASLEEALALLRSELEE-LSEELRELES 908

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515  884 ERTELEMKLREQHTETEALRAQREEERTQAD------SALYQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 952
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 937-1511 3.87e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  937 QTQKELADASQQLERL------------------RQDMKVQKLKEQETTgmLQAQLRGAQ--------QELKEAIQQHRD 990
Cdd:COG1196    176 EAERKLEATEENLERLedilgelerqleplerqaEKAERYRELKEELKE--LEAELLLLKlreleaelEELEAELEELEA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  991 DLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADS 1070
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1071 VRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQL 1150
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1151 RSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPwGSDPDQNGASRLLKRGPLLTALSA 1230
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1231 EAVALALQKLHQDL---WKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSEL----QDLQRQLSQSQEEKSKWEGKQNSL 1303
Cdd:COG1196    493 LLLLLEAEADYEGFlegVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1304 ESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLK 1383
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1384 NEEIESERERAQALQEQGELKVAQGKALQENLTLLAQtlSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSRE 1463
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA--EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1958767515 1464 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREA 1511
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 469-1196 1.31e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.31e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  469 LQTARGELQQQLEVLEQE---AWRLRRVNVEL-QLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELI 544
Cdd:TIGR02168  191 LEDILNELERQLKSLERQaekAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  545 ALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLE 624
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  625 QENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELrgAREEKEELKEKLNEAHHQQ 704
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL--ERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  705 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQ-QNSV 783
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  784 IQVTK--SQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQA------ALERQKVAHEEE 855
Cdd:TIGR02168  509 KALLKnqSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  856 VNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREeerTQADSALYQMQLETEKERVSLLETL 935
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK---LRPGYRIVTLDGDLVRPGGVITGGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  936 LQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAqLRGAQQELKEAIQQHRddlaafqKDKIDLQKQVEDLTSQLVT 1015
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAE-LRKELEELEEELEQLR-------KELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1016 HNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGV 1095
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1096 QVELLRQEVKEKEADfVAREAQLLEELEASRIAERQVRASLwaqEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLR 1175
Cdd:TIGR02168  818 EAANLRERLESLERR-IAATERRLEDLEEQIEELSEDIESL---AAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          730       740
                   ....*....|....*....|.
gi 1958767515 1176 SLYSVLQQALGSACERRPELR 1196
Cdd:TIGR02168  894 SELEELSEELRELESKRSELR 914
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 815-1544 2.62e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 2.62e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  815 ELDTERSHAEQERDAVARQLAQAEqegqaALERQKVAHEEEVNRLQEKWEKERALLQQKLD-------KTLETLERERTE 887
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLD-----LIIDEKRQQLERLRREREKAERYQALLKEKREyegyellKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  888 LEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRqdmKVQKLKEQEtt 967
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE---RSIAEKERE-- 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  968 gmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKE 1047
Cdd:TIGR02169  317 ---LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1048 KASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEadfvareaQLLEELEASRI 1127
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE--------WKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1128 AERQvraSLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQA----------LGSACERRP---E 1194
Cdd:TIGR02169  466 KYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgtvaqLGSVGERYAtaiE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1195 LRGGGDSVPTPWGSDPDQNGASRLLKR-----------------GPLLTALS------------------AEAVALALQK 1239
Cdd:TIGR02169  543 VAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflplnkmrdeRRDLSILSedgvigfavdlvefdpkyEPAFKYVFGD 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1240 --LHQDLWKAQQARDDLR-------------------DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEG 1298
Cdd:TIGR02169  623 tlVVEDIEAARRLMGKYRmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1299 KQNSLESELRDLHETMASLQSRLRQAElqkMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARS 1378
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLE---QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1379 AL-----KLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELL 1453
Cdd:TIGR02169  780 ALndleaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1454 SLDLKKRSREVdlqQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELendrEAQRTALEHQLLDLEQKAQVIESQ 1533
Cdd:TIGR02169  860 NGKKEELEEEL---EELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL----EAQIEKKRKRLSELKAKLEALEEE 932

                          810
                   ....*....|.
gi 1958767515 1534 RGQIQDLKKQL 1544
Cdd:TIGR02169  933 LSEIEDPKGED 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1229-1940 3.32e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1229 SAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQ-----VHSELQDLQRQLSQSQEEKSKWEGKQNSL 1303
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1304 ESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASaagvleeDLRTARSALKLK 1383
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-------DYREKLEKLKRE 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1384 NEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSRE 1463
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1464 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRD-----------QIRELENDREAQRTALEHQL------------ 1520
Cdd:TIGR02169  478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYATAIEVAAgnrlnnvvvedd 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1521 LDLEQKAQVIESQRG---------QIQDLKKQLGTLECL------------ALELEESHRKVEGQQKVITELEGQRELQ- 1578
Cdd:TIGR02169  558 AVAKEAIELLKRRKAgratflplnKMRDERRDLSILSEDgvigfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRLMg 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1579 RVALTHLTLDLEERS---------------------QELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQ 1637
Cdd:TIGR02169  638 KYRMVTLEGELFEKSgamtggsraprggilfsrsepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLERKGQELVLQKERI-QVLEDQRTLQTKILEEDLEQIKHSLR-ERGQELASQWQLMQERAEDGKSPSKAQ--R 1713
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLeELEEDLSSLEQEIENVKSELKELEARiEELEEDLHKLEEALNDLEARLSHSRIPeiQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1714 GSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEakeqgelreqvL 1793
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-----------L 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1794 QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLqEELIVEGRQ 1873
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-EDPKGEDEE 945

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1874 VRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLqDSWLQAQATLAEQEQELEALRAE 1940
Cdd:TIGR02169  946 IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILERIEE 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 829-1649 7.93e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 7.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  829 AVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKtLETLERERTELE----MKLREQHTETEALRA 904
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQ-LERLRREREKAEryqaLLKEKREYEGYELLK 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  905 QREEERTQADsalyqmqlETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEA 984
Cdd:TIGR02169  231 EKEALERQKE--------AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  985 IQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLV 1064
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1065 LQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEeLEASRiaeRQVRASLWAQEAKAA 1144
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE-LEEEK---EDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1145 QLQLQLRSTEAQLEALVAEQqpeNQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKR--- 1221
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEY---DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvge 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1222 ---GPLLTALSA---------EAVALALQKLHQD----------LWKAQQARDDL----RDQVQKLVQRLTDTEAQ-KSQ 1274
Cdd:TIGR02169  536 ryaTAIEVAAGNrlnnvvvedDAVAKEAIELLKRrkagratflpLNKMRDERRDLsilsEDGVIGFAVDLVEFDPKyEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1275 VHSELQDlqRQLSQSQEEKSKWEGKQN--SLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHL 1352
Cdd:TIGR02169  616 FKYVFGD--TLVVEDIEAARRLMGKYRmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1353 QACVTEARAQASAagvleedLRTARSALKLKNEEIESERERaqaLQEQGELKVAQGKALQENLTLLAQTLSNREREVETL 1432
Cdd:TIGR02169  694 QSELRRIENRLDE-------LSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1433 QAEVQELEKQREMQKAALEllSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQ 1512
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALN--DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1513 RTALEHQLLDLEQKaqvIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQqkvITELEGQRELQRVALTHLTLDLEER 1592
Cdd:TIGR02169  842 RIDLKEQIKSIEKE---IENLNGKKEELEEELEELEAALRDLESRLGDLKKE---RDELEAQLRELERKIEELEAQIEKK 915

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1593 SQELQTQSSQLHELENHSTRLAKELQErDQEVMSQRQQIEELQKQKEQLTQDLERKG 1649
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALE 971
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1255-1820 9.23e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.31  E-value: 9.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1255 RDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRqaelqkmEAQND 1334
Cdd:PRK02224   229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERD-------DLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1335 RELLQASKEKLSAQVEHLQACVTEaraqasaagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQEN 1414
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1415 LTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEllslDLKKRSREVdlqqeqiqeleqcRSVLEHLPMAVQEREQK 1494
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG----NAEDFLEEL-------------REERDELREREAELEAT 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1495 LSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ 1574
Cdd:PRK02224   435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1575 RElQRVALTHLtldLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQkqkeQLTQDLERKGQELvl 1654
Cdd:PRK02224   515 EE-RREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAEL-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1655 qKERIQVLEDQRTLQTKIleEDLEQIKHSLRERGQELASQWQLMQERAEDGKSpskaqrgslehlklilRDKEKEVECQQ 1734
Cdd:PRK02224   585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1735 ERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREqvlqgQLEEAQRALAQRDHELEAL 1814
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEK-------LDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEALEAL 713


                   ....*.
gi 1958767515 1815 RQEQQQ 1820
Cdd:PRK02224   714 YDEAEE 719
PTZ00121 PTZ00121
MAEBL; Provisional
 1029-1841 2.31e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 2.31e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1029 EKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRelgvqvellrqeVKEKE 1108
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK------------AEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1109 ADFVAREAQLLEELEASRIAERqvraslwAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVlqqalgsa 1188
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAED-------AKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEA-------- 1217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1189 ceRRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDdlRDQVQKLVQRLTDT 1268
Cdd:PTZ00121  1218 --RKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKAD 1293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1269 EAQKSQVHSELQDLQRQlsqsQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQ 1348
Cdd:PTZ00121  1294 EAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1349 vehlQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1428
Cdd:PTZ00121  1370 ----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1429 VETLQAEVQELEKQREMQKAALELLSLD-LKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKlsvqrDQIRELEN 1507
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEE 1520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1508 DREAQrtalehQLLDLEQKAQVIESQRGQiqDLKKQLGTLECLALELEESHRKVEGQQKVitelegqrelqrvalthltl 1587
Cdd:PTZ00121  1521 AKKAD------EAKKAEEAKKADEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKA-------------------- 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1588 dlEERSQELQTQSSQLHELEnhstrlakelQERDQEVMSQRQqiEELQKQKEQLtqdleRKGQELVLQKERIQVLEDQRT 1667
Cdd:PTZ00121  1573 --EEDKNMALRKAEEAKKAE----------EARIEEVMKLYE--EEKKMKAEEA-----KKAEEAKIKAEELKKAEEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1668 LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlkliLRDKEKEVECQQERIQELQEHMGQL 1747
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---------AKKAEEDEKKAAEALKKEAEEAKKA 1704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1748 EQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEES 1827
Cdd:PTZ00121  1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                          810
                   ....*....|....
gi 1958767515 1828 MKQKTSALQAALEQ 1841
Cdd:PTZ00121  1785 LDEEDEKRRMEVDK 1798
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1251-2099 3.01e-12

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 72.68  E-value: 3.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1251 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEekskwegKQNSLESELRDLHETMASLQSRLRQAElqKME 1330
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSA-------RESDLEQDYQAASDHLNLVQTALRQQE--KIE 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1331 A-QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkv 1405
Cdd:COG3096    351 RyQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAA---EEEVDSLKSQLADYQQALDVQQTRAiqyqQAVQ------- 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1406 AQGKAlQENLTLLAQTLSNREREVETLQAEVQELEKQRemqkaalellsLDLKKRSREVDLQQEQIQELEQcrsVLEHLP 1485
Cdd:COG3096    421 ALEKA-RALCGLPDLTPENAEDYLAAFRAKEQQATEEV-----------LELEQKLSVADAARRQFEKAYE---LVCKIA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1486 MAVqEREQKLSVQRDQIRELENDRE--AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEG 1563
Cdd:COG3096    486 GEV-ERSQAWQTARELLRRYRSQQAlaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEA 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1564 QQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQER---DQEVMSQRQQIEELQKQKEQ 1640
Cdd:COG3096    565 QLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATV 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1641 LTQDLERKGQELVLQKERIQVL---EDQRTLQTK---------------------------------ILEEDLEQIKHSL 1684
Cdd:COG3096    645 ERDELAARKQALESQIERLSQPggaEDPRLLALAerlggvllseiyddvtledapyfsalygparhaIVVPDLSAVKEQL 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1685 RERGQELASQWQLmqERAEDGKSPSKAQRGSLEHLKLIlrdKEKEVECQQERIQEL--------QEHMGQLEQQLQGLHR 1756
Cdd:COG3096    725 AGLEDCPEDLYLI--EGDPDSFDDSVFDAEELEDAVVV---KLSDRQWRYSRFPEVplfgraarEKRLEELRAERDELAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1757 KVGETSLllthREQEtatlQQRLQEAKEQ--GELREQVLQGQLEEAQRALAQR----DHELEALRQEQQQTRGQEESMKQ 1830
Cdd:COG3096    800 QYAKASF----DVQK----LQRLHQAFSQfvGGHLAVAFAPDPEAELAALRQRrselERELAQHRAQEQQLRQQLDQLKE 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1831 KTSALQAALEQAHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQA 1906
Cdd:COG3096    872 QLQLLNKLLPQANLladeTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQR 951

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1907 QEH-------EAEARTLQDSWLQAQATLAEQEQELEALR-----AENQYSRQQEEAAFGQAE---------ALQEALSKA 1965
Cdd:COG3096    952 RLKqqifalsEVVQRRPHFSYEDAVGLLGENSDLNEKLRarleqAEEARREAREQLRQAQAQysqynqvlaSLKSSRDAK 1031

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1966 QATLQEKEQRLleqAELSCTLEASTAtlqatlDTCQARARQLEEAL---RVREGEIQTQALQHQEAMQHLQQELCQKEED 2042
Cdd:COG3096   1032 QQTLQELEQEL---EELGVQADAEAE------ERARIRRDELHEELsqnRSRRSQLEKQLTRCEAEMDSLQKRLRKAERD 1102

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 2043 LRQQDEQRQ-------LLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE 2099
Cdd:COG3096   1103 YKQEREQVVqakagwcAVLRLARDNDVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEH 1166
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1628-2323 4.30e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 4.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1628 RQQIEELQKQKEQLTQDLERKGQ----ELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQELASQW-QLMQERA 1702
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAElrelELALLVLRLEELREEL-EELQEELKEAEEELEELTAELQELEEKLeELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1703 EDGKSPSKAQRGSLEHLKLIlRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEA 1782
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI-SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1783 KEQGElreqVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR 1862
Cdd:TIGR02168  357 EAELE----ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1863 LQEELIveGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQ 1942
Cdd:TIGR02168  433 AELKEL--QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA----QLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1943 YSRQQEEAAFGQAE-----------------ALQEALSK-AQATLQEKEQR------LLEQAELS-CTLEASTATLQATL 1997
Cdd:TIGR02168  507 GVKALLKNQSGLSGilgvlselisvdegyeaAIEAALGGrLQAVVVENLNAakkaiaFLKQNELGrVTFLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1998 DTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQeLCQKEEDLRQQDEQRQLLEKAV------------------AQ 2059
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG-GVLVVDDLDNALELAKKLRPGYrivtldgdlvrpggvitgGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2060 RSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEIL----MLREAQQRQNQEASSPSHRSFPAEKPSLQLLLA 2135
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEeleeELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2136 QQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 2215
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2216 -GPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRK 2294
Cdd:TIGR02168  826 lESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740
                   ....*....|....*....|....*....
gi 1958767515 2295 LkRDSLRASRAGSLEARETMNSSPTQQDG 2323
Cdd:TIGR02168  906 L-ESKRSELRRELEELREKLAQLELRLEG 933
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1372-1890 5.03e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 5.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1372 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQ-------TLSNREREVETLQAEVQELEKQRE 1444
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAeiedlreTIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1445 M----QKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQL 1520
Cdd:PRK02224   290 EleeeRDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1521 LDLEQKAQVIESQRGQIQDLKKQLGTLECLaleleeshrkVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS 1600
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRER----------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1601 SQLHELEN--------------HSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERkGQELVLQKERIQVLEDQR 1666
Cdd:PRK02224   440 ERVEEAEAlleagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1667 TLQTKILEEDLEQIKH------SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcQQERIQEL 1740
Cdd:PRK02224   519 EDLEELIAERRETIEEkreraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1741 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ 1819
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERD 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 1820 QTRGQEESMKQKTSALQaaleqahvTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDLRAESRE 1890
Cdd:PRK02224   678 DLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQ 733
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 705-1542 5.86e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 5.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  705 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQD-----LAEQVLGLRSAKEQLEGNLFEAQQ 779
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  780 QNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCL----KLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAhEEE 855
Cdd:TIGR02169  252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL-EAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  856 VNRLQEKWEKerallqqkLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADsalyqmqlETEKERVSLLETL 935
Cdd:TIGR02169  331 IDKLLAEIEE--------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA--------ETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  936 LQTQKELADASQQLERLRQDMKvqklkeqettgmlqaQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVT 1015
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQ---------------RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1016 HNDSQRLVKQEIEEKVREaqecsriQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGv 1095
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEE-------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG- 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1096 QVELLRQEVKEKEA-----------DFVAREA-QLLEELEASRIaerqvrASLWAQEAKAAQLQLQLRSTEAQLEALVA- 1162
Cdd:TIGR02169  532 SVGERYATAIEVAAgnrlnnvvvedDAVAKEAiELLKRRKAGRA------TFLPLNKMRDERRDLSILSEDGVIGFAVDl 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1163 ---EQQPENQAQAQLRSlySVLQQALGSAceRRpelRGGGDSVPTPWGSDPDQNGA----SRLLKRGPLLTAL---SAEA 1232
Cdd:TIGR02169  606 vefDPKYEPAFKYVFGD--TLVVEDIEAA--RR---LMGKYRMVTLEGELFEKSGAmtggSRAPRGGILFSRSepaELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1233 VALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHE 1312
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1313 TMASLQSRLRQaelqkmeaqndrelLQASKEKLSAQVEHLQACVTEARAQASAAgvLEEDLRTARSALKLKNEEIESERE 1392
Cdd:TIGR02169  759 ELKELEARIEE--------------LEEDLHKLEEALNDLEARLSHSRIPEIQA--ELSKLEEEVSRIEARLREIEQKLN 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1393 RAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQ 1472
Cdd:TIGR02169  823 RLTLEKEYLEKEIQE---LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1473 eleqcrsvlehlpmAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKK 1542
Cdd:TIGR02169  900 --------------ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED 955
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 811-1648 6.45e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  811 CLKLELDTERSHAEQERDAvARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEM 890
Cdd:pfam02463  191 DLEELKLQELKLKEQAKKA-LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQ 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  891 KLREQhteTEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGML 970
Cdd:pfam02463  270 VLKEN---KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  971 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1050
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1051 LTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAER 1130
Cdd:pfam02463  427 EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1131 QVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPElrgggdsvptpWGSDP 1210
Cdd:pfam02463  507 SGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL-----------TELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1211 DQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ 1290
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1291 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLE 1370
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1371 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLlAQTLSNREREVETLQAEVQELEKQREMQKAAL 1450
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1451 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1530
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1531 ESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK-----VITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHE 1605
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILlkyeeEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767515 1606 LENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1648
Cdd:pfam02463  975 VNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 1638-2312 1.28e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLERKGQELVLQKERIQVLEDQRtLQTKILEEDLEQIKHSLRERGQElaSQWQLMQERAEDGKSPSKAQRGSLE 1717
Cdd:PTZ00121  1043 KEKDIIDEDIDGNHEGKAEAKAHVGQDEG-LKPSYKDFDFDAKEDNRADEATE--EAFGKAEEAKKTETGKAEEARKAEE 1119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETAtlqQRLQEAKEQGELREQVLQGQL 1797
Cdd:PTZ00121  1120 AKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDA---KKAEAARKAEEVRKAEELRKA 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRALAQRDHE----LEALRQEQQQTRGQ-----EESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR-LQEEL 1867
Cdd:PTZ00121  1197 EDARKAEAARKAEeerkAEEARKAEDAKKAEavkkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAaIKAEE 1276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1868 IVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE--QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 1945
Cdd:PTZ00121  1277 ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1946 QQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleASTATLQATLDTCQARARQLEEALRVREGEIQTQALQH 2025
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK------ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEK 1430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2026 QEAmqhlqQELCQKEEDLRQQDE-QRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 2104
Cdd:PTZ00121  1431 KKA-----DEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA 1505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2105 REAQQRQNQEASSpshrsfpAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQE--IAM 2182
Cdd:PTZ00121  1506 AEAKKKADEAKKA-------EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedKNM 1578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2183 FLQASVLERESEQQRLQEELVLSRQALE---EQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLER 2259
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKmkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE 1658

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767515 2260 LQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAGSLEARE 2312
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711
PTZ00121 PTZ00121
MAEBL; Provisional
 398-1043 1.40e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  398 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARgELQ 477
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-EAK 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  478 QQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERErlqetlvGLEAKQSESLSELIALREALESSRLAG 557
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE-------AAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  558 ELLKQEQEEVAAALARAEQSIVELSSSENSLKAEvaDLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAA 637
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE--EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  638 EQLRSALQVDLAEAERSREAlwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQD 717
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKA--EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  718 AERQEEAlaRAGQEKEALVRERAALEVRLQAVERdrqdlAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT 797
Cdd:PTZ00121  1551 LKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  798 IIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE----EEVNRLQE---KWEKERALL 870
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaEEDEKKAAealKKEAEEAKK 1703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  871 QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSA---------LYQMQLETEKERVSLLETLLQTQKE 941
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdeeekkkIAHLKKEEEKKAEEIRKEKEAVIEE 1783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  942 LADASQQLERLRQDMKVQKLKE---------QETTGMLQAQLRGAQQELKEAI---QQHRDDLAAFQKDKIDlQKQVEDL 1009
Cdd:PTZ00121  1784 ELDEEDEKRRMEVDKKIKDIFDnfaniieggKEGNLVINDSKEMEDSAIKEVAdskNMQLEEADAFEKHKFN-KNNENGE 1862

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1958767515 1010 TSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1043
Cdd:PTZ00121  1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1574-1901 1.44e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1574 QRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQdlerkgqelv 1653
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1654 lqkeriqvlEDQRTLQTKI--LEEDLEQIKHSLRERGQELasqwQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVE 1731
Cdd:TIGR02169  287 ---------EEQLRVKEKIgeLEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1732 CQQERIQELQEHMGQLEQQLQGLHRKVGETslllthrEQETATLQQRLQEAKEqgelreqvlqgQLEEAQRALAQRDHEL 1811
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAET-------RDELKDYREKLEKLKR-----------EINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1812 EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREH 1891
Cdd:TIGR02169  416 QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          330
                   ....*....|
gi 1958767515 1892 EKTVLALQQR 1901
Cdd:TIGR02169  496 EAQARASEER 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 243-888 1.45e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  243 AQLLLLVAKTQALEKEAHEKSQELMQLKSQGDlekaELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAEL 322
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLD----ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  323 MEHEASLSRNAQEEKLSLQHVIKDITQALASVEEedtvtqtpgSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQA 402
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIASLNNEIERLEARLER---------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  403 VQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGE---VDSLSKERELLQTARGELQQQ 479
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFsegVKALLKNQSGLSGILGVLSEL 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  480 LEV---------------------------------LEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQ 526
Cdd:TIGR02168  529 ISVdegyeaaieaalggrlqavvvenlnaakkaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  527 ETLVGLEAKQSESLSELI---ALREALESSR----------LAGELLK-------------QEQEEVAAALARAEQSIVE 580
Cdd:TIGR02168  609 KFDPKLRKALSYLLGGVLvvdDLDNALELAKklrpgyrivtLDGDLVRpggvitggsaktnSSILERRREIEELEEKIEE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  581 LSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWE 660
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  661 EKTHLETQLRKAEETGAELQAELRGAREekeelkeklneahhQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERA 740
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKE--------------ELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  741 ALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCL---KLELD 817
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskRSELR 914

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515  818 TERSHAEQERDAVARQLAQAEQEGQAALERQKVAHE---EEVNRLQEKWEKERALLQQKLDKtletLERERTEL 888
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltlEEAEALENKIEDDEEEARRRLKR----LENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 647-1451 1.85e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.09  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  647 DLAEAERSREALWEEKTHLE----TQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQE 722
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEeakkTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  723 EA----LARAGQEKEALVRERAALEVRLQAVERDrqdlAEQVLGLRSAKEqlegnlfeAQQQNSVIQVTKSQLEVQIQTI 798
Cdd:PTZ00121  1162 DArkaeEARKAEDAKKAEAARKAEEVRKAEELRK----AEDARKAEAARK--------AEEERKAEEARKAEDAKKAEAV 1229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  799 IQAKEVIQGEVKCLKLEldTERSHAEQERDAVARQLAQAEQegQAALERQKVAHEEEVNRLQEKwekerallqQKLDKTL 878
Cdd:PTZ00121  1230 KKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARR--QAAIKAEEARKADELKKAEEK---------KKADEAK 1296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  879 ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSlletllqtQKELADASQQLERLRQDMKV 958
Cdd:PTZ00121  1297 KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA--------KAEAEAAADEAEAAEEKAEA 1368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  959 QKLKEQETtgmlqaqlRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEdltsqlVTHNDSQRLVKQEIEEKVREAQECS 1038
Cdd:PTZ00121  1369 AEKKKEEA--------KKKADAAKKKAEEKKKADEAKKKAEEDKKKADE------LKKAAAAKKKADEAKKKAEEKKKAD 1434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1039 RIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQrelgvqvellrqEVKEKEADFVAREAQL 1118
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD------------EAKKKAEEAKKKADEA 1502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1119 LEELEASRIAERQVRAslwaQEAKAAQlqlQLRSTEAQLEALVAEQQPENQAQAQLRSlysvlQQALGSACERRpelrgg 1198
Cdd:PTZ00121  1503 KKAAEAKKKADEAKKA----EEAKKAD---EAKKAEEAKKADEAKKAEEKKKADELKK-----AEELKKAEEKK------ 1564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1199 gdSVPTPWGSDPDQNGASRllkrgplltalSAEavalalqklhqdlwKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSE 1278
Cdd:PTZ00121  1565 --KAEEAKKAEEDKNMALR-----------KAE--------------EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1279 LQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHET-MASLQSRLRQAELQKMEAQNDRELLQASKEKlsaqvehlqacvT 1357
Cdd:PTZ00121  1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE------------E 1685

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1358 EARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQAlQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 1437
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA-EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                          810
                   ....*....|....
gi 1958767515 1438 ELEKQREMQKAALE 1451
Cdd:PTZ00121  1765 EEEKKAEEIRKEKE 1778
PTZ00121 PTZ00121
MAEBL; Provisional
 484-1058 3.53e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  484 EQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQE 563
Cdd:PTZ00121  1239 AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD 1318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  564 QEEVAAALARAEQSIVELSSSENSLKAEVA--DLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSmCSRVEAAEQLR 641
Cdd:PTZ00121  1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAkaEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-AEEKKKADEAK 1397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  642 SALQVDLAEAERSREALWEEKTHLETQLRKAEETGAElqaELRGAREEKEELKEKLNEAHHQQEAAtaQLQQLHQDAERQ 721
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD---EAKKKAEEAKKADEAKKKAEEAKKAE--EAKKKAEEAKKA 1472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  722 EEALARAGQEKEALVRERAALEVRLQAVE-RDRQDLAEQVLGLRSAKEQLEGN-LFEAQQQNSVIQVTKSQLEVQIQTII 799
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKKADeAKKAEEAKKADEAKKAEEKKKADELK 1552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  800 QAKEVIQGEVKcLKLEldtERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEK-ERALLQQKLDKTL 878
Cdd:PTZ00121  1553 KAEELKKAEEK-KKAE---EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKaEEAKIKAEELKKA 1628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  879 ETLERERTELEMKLREQHTETEALRAQREEERTQADsalyQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKV 958
Cdd:PTZ00121  1629 EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA----EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  959 QKLKEQETTGMLQAQlrgaqqELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECS 1038
Cdd:PTZ00121  1705 EELKKKEAEEKKKAE------ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778

                          570       580
                   ....*....|....*....|
gi 1958767515 1039 RIQKELEKEKASLTLSLVEK 1058
Cdd:PTZ00121  1779 AVIEEELDEEDEKRRMEVDK 1798
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1482-2296 3.84e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 3.84e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1482 EHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQlgtleclaleLEESHRKV 1561
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1562 EGQ-QKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHEL--------------------------ENHSTRLA 1614
Cdd:pfam15921  144 RNQlQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeeasgkkiyehdsmstmhfRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1615 KELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQ-KERIQVLEDQRTLQTKILEEDleqiKHSLRERGQELAS 1693
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEK----ASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1694 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEcqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1773
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1774 TLQQRLQEAKEQGELREQVLQGQLEEAQRaLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlkERQGEL 1853
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS------ECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1854 EEHRGQVQRLQEELivegrqvraleEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDswlqAQATLAEQEQE 1933
Cdd:pfam15921  447 ERQMAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1934 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQlEEALRV 2013
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT-AGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2014 REGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEkaVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLT 2093
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2094 VAQKEEEILMLREAQQRQNQEASSPSHrsfpaeKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKAS 2173
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTN------KLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ 742

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2174 ISSLQEIAMFLQASVLERESEQQRLQEElvlsRQALEEQQSrgphsssradqgpkagqdtepgeVIEAEPSPGVGEKEQL 2253
Cdd:pfam15921  743 IDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELS-----------------------TVATEKNKMAGELEVL 795

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1958767515 2254 RQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLK 2296
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
PTZ00121 PTZ00121
MAEBL; Provisional
 1489-2215 4.28e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 4.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1489 QEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV--IESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 1566
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETgkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1567 viTELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnhsTRLAKELQERDQ-------EVMSQRQQIEELQKQKE 1639
Cdd:PTZ00121  1148 --AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAEELRKAEDarkaeaaRKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1640 QLTQDLERKGQELVLQKERIQVLEDQRTLQtKILEEDLEQIKHSLRERGQELASQWQLMQE--RAEDGKSPSKAQRGslE 1717
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNE-EIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKA--E 1299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLILRDKEKEVEcqQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQvlqgQL 1797
Cdd:PTZ00121  1300 EKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK----KK 1373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRalaqrdhELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRAL 1877
Cdd:PTZ00121  1374 EEAKK-------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1878 EEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQatlaEQEQELEALRAENQYSRQQEEAAFGQAEA 1957
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE----EAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1958 LQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEE----ALRVREGEIQTQALQHQEAMQHLQ 2033
Cdd:PTZ00121  1523 KADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmALRKAEEAKKAEEARIEEVMKLYE 1602

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2034 QELCQKEEDLRQQDEQR---QLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEE----ILMLRE 2106
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKikaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKK 1682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2107 AQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREI---EWREKAQGLALSLAQSKASISSLQEIAMF 2183
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIkaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHL 1762

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1958767515 2184 LQASvlERESEQQRLQEELVLSRQALEEQQSR 2215
Cdd:PTZ00121  1763 KKEE--EKKAEEIRKEKEAVIEEELDEEDEKR 1792
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 429-1185 5.63e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 5.63e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  429 EEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELlQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEK 508
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAL-LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  509 LEQQ-EELHLAVRERERLQETLvgleAKQSESLS--ELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSE 585
Cdd:TIGR02169  256 LTEEiSELEKRLEEIEQLLEEL----NKKIKDLGeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  586 NSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHL 665
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  666 ETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVR 745
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  746 LQAVERDRQDLAEQVLGLRSAKEQLEGNL--------------------FEAQQQNSVIQVTKSQLEVQIQTIIQAKEVI 805
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIELLKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  806 QGEVKCLKL------ELDTERSHAEQERDaVARQLAQAEQEGQAAlerqkVAHEEEVNRLQEKWEKERALLQQKLDKTL- 878
Cdd:TIGR02169  572 AGRATFLPLnkmrdeRRDLSILSEDGVIG-FAVDLVEFDPKYEPA-----FKYVFGDTLVVEDIEAARRLMGKYRMVTLe 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  879 -ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLL-QTQKELADASQQLERLRQDM 956
Cdd:TIGR02169  646 gELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLdELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  957 KvQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLvtHNDSQRLVKQEIEEKVREAQE 1036
Cdd:TIGR02169  726 E-QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1037 csriqkeLEKEKASLTLSLVEKEKRLlvlqeadSVRQRELVSLRQDIQEAQEGQRELGVQvellRQEVKEKEADFVAREA 1116
Cdd:TIGR02169  803 -------LEEEVSRIEARLREIEQKL-------NRLTLEKEYLEKEIQELQEQRIDLKEQ----IKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767515 1117 QLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQAL 1185
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 246-954 7.25e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 7.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  246 LLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEH 325
Cdd:TIGR02169  191 LIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  326 EASLS-------RNAQEEKLSLQHVIKDITQALASVE--EEDTVTQTPGSENSLQSDYNDLSQFDSQ--DPNKALTLVHS 394
Cdd:TIGR02169  271 EQLLEelnkkikDLGEEEQLRVKEKIGELEAEIASLErsIAEKERELEDAEERLAKLEAEIDKLLAEieELEREIEEERK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  395 VLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDalagqtvDLQGEVDSLSKERELLQTARG 474
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-------ELKRELDRLQEELQRLSEELA 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  475 ELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSR 554
Cdd:TIGR02169  424 DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  555 LAGELLKQEQEEVAAALARAEQSIVELSSSE------------NSLKAEVADLRAAAVKLGALNEA--------LALDKV 614
Cdd:TIGR02169  504 ERVRGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaagNRLNNVVVEDDAVAKEAIELLKRrkagratfLPLNKM 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  615 ALNQQLLQLEQENQSM--------------------------CSRVEAAEQL---------------RSALQVDLAEAER 653
Cdd:TIGR02169  584 RDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgdtlvVEDIEAARRLmgkyrmvtlegelfeKSGAMTGGSRAPR 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  654 SRE----ALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAG 729
Cdd:TIGR02169  664 GGIlfsrSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  730 QEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQ-IQTIIQAKEVIQGE 808
Cdd:TIGR02169  744 EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSrIEARLREIEQKLNR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  809 VKCLKLELDTERSHAEQERDAVARQLAQAEQEgQAALERQKVAHEEEVNrlqekwEKERALLQqkLDKTLETLERERTEL 888
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-IENLNGKKEELEEELE------ELEAALRD--LESRLGDLKKERDEL 894

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515  889 EMKLREQHTETEALRAQREEERTQAdsALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 954
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIEKKRKRL--SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1237-2054 7.31e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 7.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1237 LQKLHQDLWKAQQARDDLRDQVQK-LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEkskwegkqnsleseLRDLHETMA 1315
Cdd:TIGR02169  203 LRREREKAERYQALLKEKREYEGYeLLKEKEALERQKEAIERQLASLEEELEKLTEE--------------ISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1316 SLQSRLRQAELQKMEAQNDREL-LQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERA 1394
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1395 QALQEQgelkvaqgkalqenltlLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL 1474
Cdd:TIGR02169  349 RKRRDK-----------------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1475 EQcrsVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALEL 1554
Cdd:TIGR02169  412 QE---ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1555 EESHRKVEGQQKVIteleGQRELQRVALTHLtldLEERSQELQTQSSQLHEL-ENHSTRLAKELQERDQEVMSQRqqiEE 1633
Cdd:TIGR02169  489 QRELAEAEAQARAS----EERVRGGRAVEEV---LKASIQGVHGTVAQLGSVgERYATAIEVAAGNRLNNVVVED---DA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1634 LQKQKEQLTQDlERKGQELVLQKERIQvleDQRTLQTKILEEDLEQIKHSLRERGQELAS------QWQLMQERAEDGK- 1706
Cdd:TIGR02169  559 VAKEAIELLKR-RKAGRATFLPLNKMR---DERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvfGDTLVVEDIEAARr 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1707 ---------------SPSKAQRG---SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHR 1768
Cdd:TIGR02169  635 lmgkyrmvtlegelfEKSGAMTGgsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1769 EQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ-----AH 1843
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQE----EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1844 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHE---AEARTLQDSW 1920
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1921 LQAQATLAEQEQELEAL-----RAENQYSRQQE--EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 1993
Cdd:TIGR02169  871 EELEAALRDLESRLGDLkkerdELEAQLRELERkiEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 1994 qATLDTCQARARQLEEALRvREGEIQTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLE 2054
Cdd:TIGR02169  951 -LSLEDVQAELQRVEEEIR-ALEPVNMLAIQEYEEVLKRLDELKEKRAKL--EEERKAILE 1007
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
398-887 7.96e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 7.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  398 RRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVD-LQGEVDSLSKERELLQTARGEL 476
Cdd:COG4913    285 FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  477 QQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAV-----------RERERLQETLVGLEAKQSESLSELIA 545
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalrdlrRELRELEAEIASLERRKSNIPARLLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  546 LREALESS--------RLAGELL--KQEQEEVAAALARAeqsiveLSSSENSLKAEVADLRAAAVKLGALNEALALD--K 613
Cdd:COG4913    445 LRDALAEAlgldeaelPFVGELIevRPEEERWRGAIERV------LGGFALTLLVPPEHYAAALRWVNRLHLRGRLVyeR 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  614 VALNQQLLQLEQ-ENQSMCSRVEAAE-QLRSALQVDLAEAE-----RSREALWEEKTHL-ETQLRKAEETGAELqaelrG 685
Cdd:COG4913    519 VRTGLPDPERPRlDPDSLAGKLDFKPhPFRAWLEAELGRRFdyvcvDSPEELRRHPRAItRAGQVKGNGTRHEK-----D 593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  686 AREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQDLAEQVLGLRS 765
Cdd:COG4913    594 DRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDVASAEREIAE 672

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  766 AKEQLEgNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKclklELDTERSHAEQERDAVARQLAQAEQEGQAAL 845
Cdd:COG4913    673 LEAELE-RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIG----RLEKELEQAEEELDELQDRLEAAEDLARLEL 747

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 1958767515  846 E------RQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTE 887
Cdd:COG4913    748 RalleerFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 702-1438 9.26e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 9.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  702 HQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAE-QVLGLRSAKEQLEGNLFEAQQQ 780
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERS 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  781 NSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERshaeQERDAVARQLAQAEQEgqaalERQKVAHEEEVNRLQ 860
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER----KRRDKLTEEYAELKEE-----LEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 EKWEKERALLQQKLDKtletLERERTELEMKLREQHTETEALRAQREEERTQADSALYQM-QLETEKERVslletllqtQ 939
Cdd:TIGR02169  381 AETRDELKDYREKLEK----LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKInELEEEKEDK---------A 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  940 KELADASQQLERLRQDM---KVQKLKEQETTGMLQAQLRGAQQEL------KEAIQQHRDDLAAFQKDKIDLQKQVEDLT 1010
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLskyEQELYDLKEEYDRVEKELSKLQRELaeaeaqARASEERVRGGRAVEEVLKASIQGVHGTV 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1011 SQLVTHND----------SQRLVKQEIEEKVrEAQECSRIQKELEKEKAS-LTLSLVEKEKRLLVLQEADSVRQRELVSL 1079
Cdd:TIGR02169  528 AQLGSVGEryataievaaGNRLNNVVVEDDA-VAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLV 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1080 RQDIQEAQEGQRELGVQVELLRQEVKEK---EADFVAREAQLLEE---LEASRIAERQVRASLWAQEAKAAQLQLQLRST 1153
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTLVVEDIEAARRlmgKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1154 EAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGggdsvptpwgsdpdqngasrllkrgplltalSAEAV 1233
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ-------------------------------EEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1234 ALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQS-----QEEKSKWEGKQNSLESELR 1308
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVSRIEARLR 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1309 DLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIE 1388
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1389 SERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQE 1438
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
513-1062 1.27e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 1.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  513 EELHLAVRERERLQETLVGLEA------KQSESLSELIALREALES--SRLAGELLKQEQEEVAAALARAEQSIVELSSS 584
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRElaeryaAARERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  585 ENSLKAEVADLRAAAVKLGAlnealaldkvalnqqllqleqenqsmcSRVEAAEQLRSALQVDLAEAERSREALweekth 664
Cdd:COG4913    318 LDALREELDELEAQIRGNGG---------------------------DRLEQLEREIERLERELEERERRRARL------ 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  665 lETQLRKAEETGAELQAELRgareekeelkeklneahHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEV 744
Cdd:COG4913    365 -EALLAALGLPLPASAEEFA-----------------ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  745 RLQAVERDRQDLAEQVLGLRSA-KEQLE---------GNLF-----EAQQQNSVIQVTKSQ---LEVQIQTIIQAKEVI- 805
Cdd:COG4913    427 EIASLERRKSNIPARLLALRDAlAEALGldeaelpfvGELIevrpeEERWRGAIERVLGGFaltLLVPPEHYAAALRWVn 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  806 ----QGEVKCLKLELDTERSHAEQ-ERDAVARQLAQAEQEGQAALERQ--------KVAHEEEVNRLQ------------ 860
Cdd:COG4913    507 rlhlRGRLVYERVRTGLPDPERPRlDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvCVDSPEELRRHPraitragqvkgn 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 --------EKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADsaLYQMQLETEKERVSll 932
Cdd:COG4913    587 gtrhekddRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE--ALQRLAEYSWDEID-- 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  933 etLLQTQKELADASQQLERLRQDM-KVQKLKEQEttgmlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTS 1011
Cdd:COG4913    663 --VASAEREIAELEAELERLDASSdDLAALEEQL------EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 1012 QLVTHNDSQRL-VKQEIEEKVREAQEC---SRIQKELEKEKASLTLSLVEKEKRL 1062
Cdd:COG4913    735 RLEAAEDLARLeLRALLEERFAAALGDaveRELRENLEERIDALRARLNRAEEEL 789
mukB PRK04863
chromosome partition protein MukB;
1261-2101 1.61e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 63.82  E-value: 1.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1261 LVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElQKMEAQNDRELLQA 1340
Cdd:PRK04863   284 HLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQE-KIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1341 SKEKLSAQVEHLQACVTEARAQASAAgvlEEDLRTARSALKLKNEEIESERERA----QALQeqgelkvaqgkALQENLT 1416
Cdd:PRK04863   363 RLEEQNEVVEEADEQQEENEARAEAA---EEEVDELKSQLADYQQALDVQQTRAiqyqQAVQ-----------ALERAKQ 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1417 LLAQ---TLSNREREVETLQAEVQElekqremqkAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEhlpmavQEREQ 1493
Cdd:PRK04863   429 LCGLpdlTADNAEDWLEEFQAKEQE---------ATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGE------VSRSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1494 KLSVQRDQIRELENDR--EAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITEL 1571
Cdd:PRK04863   494 AWDVARELLRRLREQRhlAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSES 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1572 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAK---ELQERDQEVMSQRQQIEELQKQKEQLTQDLERK 1648
Cdd:PRK04863   574 VSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREqsgEEFEDSQDVTEYMQQLLERERELTVERDELAAR 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1649 GQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHS-------LRERGQELASQWQLMQ----ERAEDGKSPSKAQRGSLE 1717
Cdd:PRK04863   654 KQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSeiyddvsLEDAPYFSALYGPARHaivvPDLSDAAEQLAGLEDCPE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLKLI------LRDKEKEVE-----------------------------CQQERIQELQEHMGQLEQQLQGLHRKVGETS 1762
Cdd:PRK04863   734 DLYLIegdpdsFDDSVFSVEelekavvvkiadrqwrysrfpevplfgraAREKRIEQLRAEREELAERYATLSFDVQKLQ 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1763 LLLTHREQETAT-LQQRLQEAKEQgelreqvlqgQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 1841
Cdd:PRK04863   814 RLHQAFSRFIGShLAVAFEADPEA----------ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPR 883

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1842 AHV----TLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEktvlalqqrcaeqaqeheaearTLQ 1917
Cdd:PRK04863   884 LNLladeTLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFE----------------------QLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1918 DSWLQAQATLAEQEQELEALRAENqysrqQEEAAFGQAEAlQEALSKAQAtLQEKEQRLLEQAELSCTlEASTATLQAtl 1997
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTEVV-----QRRAHFSYEDA-AEMLAKNSD-LNEKLRQRLEQAEQERT-RAREQLRQA-- 1011

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1998 dtcQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQR--QLLEKAVAQRSQENGIQEKQSLEqe 2075
Cdd:PRK04863  1012 ---QAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARrdELHARLSANRSRRNQLEKQLTFC-- 1086

                          890       900
                   ....*....|....*....|....*.
gi 1958767515 2076 kEEETRGLLESLKELQLTVAQKEEEI 2101
Cdd:PRK04863  1087 -EAEMDNLTKKLRKLERDYHEMREQV 1111
PTZ00121 PTZ00121
MAEBL; Provisional
 1242-1881 4.42e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 4.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1242 QDLWKAQQARDDLRDQVQKLVQRLTDTE-AQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSR 1320
Cdd:PTZ00121  1197 EDARKAEAARKAEEERKAEEARKAEDAKkAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE 1276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1321 LRQA-ELQKMEAQNDRELLQASKEKlsAQVEHLQACVTEARAQASAAGVLEEDLRTArSALKLKNEEiesERERAQALQE 1399
Cdd:PTZ00121  1277 ARKAdELKKAEEKKKADEAKKAEEK--KKADEAKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEE---AKKAAEAAKA 1350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1400 QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELlsldlKKRSREVDLQQEQIQELEQCRS 1479
Cdd:PTZ00121  1351 EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-----KKKADELKKAAAAKKKADEAKK 1425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1480 VLEHLPMAvqEREQKLSVQRDQIRELENDREAQRTALEhqlldLEQKAQviesQRGQIQDLKKQlgtlECLALELEESHR 1559
Cdd:PTZ00121  1426 KAEEKKKA--DEAKKKAEEAKKADEAKKKAEEAKKAEE-----AKKKAE----EAKKADEAKKK----AEEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1560 KVEGQQKVITELEGQRELQRVALthltldlEERSQELQTQSSQLHELEnhstrlakelqerdqevmsQRQQIEELQKQKE 1639
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKAD-------EAKKAEEAKKADEAKKAE-------------------EAKKADEAKKAEE 1544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1640 QLTQDLERKGQELVLQKERIQVLEDQRTLQTKILE----EDLEQIKHSLRERGQELASQWQLMqeRAEDGKSPSKAqRGS 1715
Cdd:PTZ00121  1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAlrkaEEAKKAEEARIEEVMKLYEEEKKM--KAEEAKKAEEA-KIK 1621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1716 LEHLKlilrdKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQG 1795
Cdd:PTZ00121  1622 AEELK-----KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQeQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGElEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:PTZ00121  1697 EAEEAKKAEELKKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIR 1774


                   ....*.
gi 1958767515 1876 ALEEVL 1881
Cdd:PTZ00121  1775 KEKEAV 1780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1023-1804 7.32e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 7.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1023 VKQEIEEKVREAQECSRIQK-ELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLR 1101
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1102 QEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVL 1181
Cdd:TIGR02169  276 ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1182 QQALGSACERRPELRGGGDSVPTPWGSDPDQNGASR------LLKRGPLLTALSaeAVALALQKLHQDLWKAQQARDDLR 1255
Cdd:TIGR02169  356 TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRekleklKREINELKRELD--RLQEELQRLSEELADLNAAIAGIE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1256 DQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDR 1335
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1336 ELLQASKEKLSAQVEHL------QACVTEARAQASAAGVLEEDLRTARSALKLKNE------------EIESERERAQAL 1397
Cdd:TIGR02169  514 EVLKASIQGVHGTVAQLgsvgerYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1398 QEQGELKVAQgkalqeNLTLLAQTLSNREREVETLQAEVQELEKQRE-MQKAALELLSLDLKKRSRE-VDLQQEQIQELE 1475
Cdd:TIGR02169  594 SEDGVIGFAV------DLVEFDPKYEPAFKYVFGDTLVVEDIEAARRlMGKYRMVTLEGELFEKSGAmTGGSRAPRGGIL 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1476 QCRSVLEHLPMaVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDlkkqlgtleclalELE 1555
Cdd:TIGR02169  668 FSRSEPAELQR-LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ-------------EEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1556 ESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRlaKELQERDQEVMSQRQQIEELQ 1635
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1636 KQKEQLTQDLERKGQELVLQKERIQVLEDQRtlqtkileEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS 1715
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQEQR--------IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1716 LEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLqg 1795
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQ-- 961


                   ....*....
gi 1958767515 1796 QLEEAQRAL 1804
Cdd:TIGR02169  962 RVEEEIRAL 970
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
633-1178 7.52e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 7.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  633 RVEAAEQLRSALQvDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAhhQQEAATAQLQ 712
Cdd:COG4913    243 ALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEA--ELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  713 QLHQDAERQEEALARA-GQEKEALVRERAALEVRLQAVERDRQDLAEQV----LGLRSAKEQLEGNLFEAQQQNSVIQVT 787
Cdd:COG4913    320 ALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLaalgLPLPASAEEFAALRAEAAALLEALEEE 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  788 KSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERS-------HAEQERDAVARQLAQAEQEGQAALERQKVAHEEEvnrlq 860
Cdd:COG4913    400 LEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDALAEALGLDEAELPFVGELIEVRPEEE----- 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 eKWEK--ERALLQQKL-----DKTLETLER--ERTELEMKLREQHTETEALRAQREeeRTQADSALYQMQLETEKERvSL 931
Cdd:COG4913    475 -RWRGaiERVLGGFALtllvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERP--RLDPDSLAGKLDFKPHPFR-AW 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  932 LETLLQTQKELA--DASQQLERLRQDMKVQKL-KEQETTGMLQAQLRGAQQ------------ELKEAIQQHRDDLAAFQ 996
Cdd:COG4913    551 LEAELGRRFDYVcvDSPEELRRHPRAITRAGQvKGNGTRHEKDDRRRIRSRyvlgfdnraklaALEAELAELEEELAEAE 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  997 KDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEekVREAQEcsRIQkELEKEKASLTLSLVEkekrllvLQEAdsvrQREL 1076
Cdd:COG4913    631 ERLEALEAELDALQERREALQRLAEYSWDEID--VASAER--EIA-ELEAELERLDASSDD-------LAAL----EEQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1077 VSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQ 1156
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774

                          570       580
                   ....*....|....*....|..
gi 1958767515 1157 LEALVAEQQPENQAQAQLRSLY 1178
Cdd:COG4913    775 IDALRARLNRAEEELERAMRAF 796
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1735-1939 1.04e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1735 ERIQELQEHMGQLEqqlqGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEAL 1814
Cdd:COG4913    225 EAADALVEHFDDLE----RAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1815 RQEQQQTRGQEESMKQKTSALQAALEQAHVT---------------LKERQGELEEHRGQVQRLQEELIVEGRQVRALEE 1879
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQirgnggdrleqlereIERLERELEERERRRARLEALLAALGLPLPASAE 380

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1880 VLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARtlqdswlQAQATLAEQEQELEALRA 1939
Cdd:COG4913    381 EFAALRAEAAALLEALEEELEALEEALAEAEAALR-------DLRRELRELEAEIASLER 433
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
921-1451 2.07e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 2.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  921 QLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKI 1000
Cdd:COG4913    243 ALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRR---LELLEAELEELRAELARLEAELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1001 DLQKQVEDLTSQLVThNDSQRL--VKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVS 1078
Cdd:COG4913    320 ALREELDELEAQIRG-NGGDRLeqLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE---AAALLEA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1079 LRQDIQEAQEGQRELGVQVELLRQEVKEKEADfvareaqlLEELEA--SRIAERQVRA-SLWAQEAKAAQLQL------- 1148
Cdd:COG4913    396 LEEELEALEEALAEAEAALRDLRRELRELEAE--------IASLERrkSNIPARLLALrDALAEALGLDEAELpfvgeli 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1149 QLRSTEAQLEA-------------LVAEQQpENQAQAQLRSL-------YSVLQQALGSACERRPE---LRGGGDSVPTP 1205
Cdd:COG4913    468 EVRPEEERWRGaiervlggfaltlLVPPEH-YAAALRWVNRLhlrgrlvYERVRTGLPDPERPRLDpdsLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1206 WGSDPDQngasRLLKRGPLLTALSAE-------AVALALQ-KLHQDLWKAQQARD---------DLRDQVQKLVQRLTDT 1268
Cdd:COG4913    547 FRAWLEA----ELGRRFDYVCVDSPEelrrhprAITRAGQvKGNGTRHEKDDRRRirsryvlgfDNRAKLAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1269 EAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRdlhetMASLQSRLRQAELQKMEAQNDrellqaskeklSAQ 1348
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEID-----VASAEREIAELEAELERLDAS-----------SDD 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1349 VEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1428
Cdd:COG4913    687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766

                          570       580
                   ....*....|....*....|....
gi 1958767515 1429 V-ETLQAEVQELEKQREMQKAALE 1451
Cdd:COG4913    767 LrENLEERIDALRARLNRAEEELE 790
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
396-955 2.18e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 2.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  396 LTRRQQAVQDLRQQLsgcqEAMSFLQQQHNQWEEegkaLRERLQKLTGERDALAGQTvdLQGEVDSLSKERELLQTARGE 475
Cdd:COG4913    237 LERAHEALEDAREQI----ELLEPIRELAERYAA----ARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  476 LQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQ--------QEELHLAVRERERLQETLVGLEAKQSESLSELIALR 547
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRLEQlereierlERELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  548 EALESSRlagELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKL--------GALNEALALDKVALNQq 619
Cdd:COG4913    387 AEAAALL---EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGLDEAELPF- 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  620 llqleqenqsMCSRVE----------AAEQ-LRSALQVDLAEAERSREAL-WEEKTHLETQLRkAEETGAELQAELRGAR 687
Cdd:COG4913    463 ----------VGELIEvrpeeerwrgAIERvLGGFALTLLVPPEHYAAALrWVNRLHLRGRLV-YERVRTGLPDPERPRL 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  688 EEKEELKEKLNEAHHQQEAATAQLQQLH--------QDAERQEEALARAGQEKEALVRERAalevrlqaveRDRQDLAEQ 759
Cdd:COG4913    532 DPDSLAGKLDFKPHPFRAWLEAELGRRFdyvcvdspEELRRHPRAITRAGQVKGNGTRHEK----------DDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  760 -VLGL--RSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERshAEQERDAVARQLAQ 836
Cdd:COG4913    602 yVLGFdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELER 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  837 AEQEGQ--AALERQKVAHEEEVNRLQEKWEkERALLQQKLDKTLETLERERTELEMKLReqhtetEALRAQREEERTQAD 914
Cdd:COG4913    680 LDASSDdlAALEEQLEELEAELEELEEELD-ELKGEIGRLEKELEQAEEELDELQDRLE------AAEDLARLELRALLE 752

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1958767515  915 SALYQMQLE--TEKERVSLLETLLQTQKELADASQQLERLRQD 955
Cdd:COG4913    753 ERFAAALGDavERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1220-1449 2.31e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1220 KRGPLLTALSAEAVALALQKLHQDlwkAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGK 1299
Cdd:COG4942      1 MRKLLLLALLLALAAAAQADAAAE---AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1300 QNSLESELRDLHETMASLQSRLRQ---------AELQKMEAQNDRELLQASK---------EKLSAQVEHLQACVTEARA 1361
Cdd:COG4942     78 LAALEAELAELEKEIAELRAELEAqkeelaellRALYRLGRQPPLALLLSPEdfldavrrlQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1362 QASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQgkaLQENLTLLAQTLSNREREVETLQAEVQELEK 1441
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEA 234


                   ....*...
gi 1958767515 1442 QREMQKAA 1449
Cdd:COG4942    235 EAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1238-2059 2.74e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1238 QKLHQDLWKAQQARD----DLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHET 1313
Cdd:pfam01576  200 EKGRQELEKAKRKLEgestDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQED 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1314 MASLQSRLRQAELQKMEAQNDRELL--------------QASKEKLSAQVEHLQACVTEARAQASAAgvLEEDLRTARSA 1379
Cdd:pfam01576  280 LESERAARNKAEKQRRDLGEELEALkteledtldttaaqQELRSKREQEVTELKKALEEETRSHEAQ--LQEMRQKHTQA 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1380 LKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQEL-------EKQREMQKAALEL 1452
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqarlsesERQRAELAEKLSK 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1453 LSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIES 1532
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1533 qrgQIQDLKKQLgtleclalelEESHRKVEGQQKVITEL-EGQRELQRvalthltlDLEERSQELQTQSSQLHELENHST 1611
Cdd:pfam01576  518 ---QLSTLQAQL----------SDMKKKLEEDAGTLEALeEGKKRLQR--------ELEALTQQLEEKAAAYDKLEKTKN 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1612 RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDL-ERKGQELVLQKERIQVLEDQRTLQTKILeedleqikhslrergqE 1690
Cdd:pfam01576  577 RLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLaEEKAISARYAEERDRAEAEAREKETRAL----------------S 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1691 LASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVecqqeriQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQ 1770
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNV-------HELERSKRALEQQVEEMKTQLEELEDELQATED 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1771 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQ 1850
Cdd:pfam01576  714 AKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKK---LELDLKELEAQIDAAN 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1851 GELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQ 1930
Cdd:pfam01576  791 KGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAE-LLQLQEDLAASERARRQAQQERDELADE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1931 EQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE-LSCTLEASTATLQATLDTCQARARQLEE 2009
Cdd:pfam01576  870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEqLTTELAAERSTSQKSESARQQLERQNKE 949

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 2010 aLRVREGEIQTQA-LQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQ 2059
Cdd:pfam01576  950 -LKAKLQEMEGTVkSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRR 999
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1359-2083 4.68e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1359 ARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQE-QGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 1437
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1438 ELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQEL------------EQCRSVLEHLPMAVQ---EREQKLSVQRD-- 1500
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigeleaeiASLERSIAEKERELEdaeERLAKLEAEIDkl 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1501 --QIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEeshRKVEGQQKVITELEGQRELQ 1578
Cdd:TIGR02169  335 laEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1579 RVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELV-LQKE 1657
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSkLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1658 RIQVLEDQRTLQT---------KILEEDLEQIKHSLRERGQeLASQWQLMQERAEDGKSPS----------------KAQ 1712
Cdd:TIGR02169  492 LAEAEAQARASEErvrggraveEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRLNNvvveddavakeaiellKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1713 RGS------LEHLKLILRDKEKE------------VECQQ----------------ERIQELQEHMGQ-----LEQQL-- 1751
Cdd:TIGR02169  571 KAGratflpLNKMRDERRDLSILsedgvigfavdlVEFDPkyepafkyvfgdtlvvEDIEAARRLMGKyrmvtLEGELfe 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1752 -----QGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelrEQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1826
Cdd:TIGR02169  651 ksgamTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE----LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1827 SMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREhektvlalqqrcaEQA 1906
Cdd:TIGR02169  727 QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-------------SRI 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1907 QEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTL 1986
Cdd:TIGR02169  794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1987 EASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGI 2066
Cdd:TIGR02169  874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL 953

                          810
                   ....*....|....*..
gi 1958767515 2067 QEKQSLEQEKEEETRGL 2083
Cdd:TIGR02169  954 EDVQAELQRVEEEIRAL 970
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1763-2215 5.13e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.81  E-value: 5.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1763 LLLTHREQETATLQQRLQEAKEQGELREQVlqGQLEEAQRALAQ-----RDH---ELEALRQEQQQTRGQEEsmkqkTSA 1834
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMAREL--EELSARESDLEQdyqaaSDHlnlVQTALRQQEKIERYQED-----LEE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1835 LQAALEQAHVTLKERQGELEEHRGQVQRLQEElivegrqVRALEEVLGDL-RAESREHEKtvlALQQRCAEQAQEheaea 1913
Cdd:COG3096    359 LTERLEEQEEVVEEAAEQLAEAEARLEAAEEE-------VDSLKSQLADYqQALDVQQTR---AIQYQQAVQALE----- 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1914 rtlqdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLleqaELSCTLEASTATL 1993
Cdd:COG3096    424 --------KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAY----ELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1994 QAtldtcQARARQLEEALRvregeiqtqALQHQ-EAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSL 2072
Cdd:COG3096    492 QA-----WQTARELLRRYR---------SQQALaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQ--LDAAEEL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2073 EQEKEEETrglleslkelqltvAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllAQQDLERLQNALRQTEAR 2152
Cdd:COG3096    556 EELLAELE--------------AQLEELEEQAAEAVEQRSE---------------------LRQQLEQLRARIKELAAR 600

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767515 2153 EIEWREKAQGLALSLAQSKASISSLQEIAMFLQaSVLERESEQQRLQEELVLSRQALEEQQSR 2215
Cdd:COG3096    601 APAWLAAQDALERLREQSGEALADSQEVTAAMQ-QLLEREREATVERDELAARKQALESQIER 662
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1852-2045 8.06e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 8.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1852 ELEEHRGQVQRLQEELIVEGRQVRALEEVLGD------LRAESREHEKTVLALQQRCAEQAQEH-EAEARTLQDSWLQAQ 1924
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELaeryaaARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1925 ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR 2003
Cdd:COG4913    309 AELERLEARLDALREElDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1958767515 2004 ARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 2045
Cdd:COG4913    389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1614-2096 9.95e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 9.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1614 AKELQERDQEVMSQRQQIEELQKQKEQLTQdLERKGQELVLQKERIQVLEDQRTLQTKileEDLEQIKHSLRERGQELAS 1693
Cdd:COG4913    227 ADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRL---WFAQRRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1694 QWQLMQERAEDGKSPSKAQRGSLEHLKLILRDK--------EKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 1765
Cdd:COG4913    303 ELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1766 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ-------EQQQTRGQ-EESMKQKTSAL-- 1835
Cdd:COG4913    383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDAlAEALGLDEAELpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1836 --------------QAALEQA------------------------------HVTLKERQGELEEHRGQV--QRLQEELIV 1869
Cdd:COG4913    463 vgelievrpeeerwRGAIERVlggfaltllvppehyaaalrwvnrlhlrgrLVYERVRTGLPDPERPRLdpDSLAGKLDF 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1870 EGRQVRA-LEEVLG------------DLRAESR-------------EHEK-------TVLALQQRCAEQAQEHEAEARTL 1916
Cdd:COG4913    543 KPHPFRAwLEAELGrrfdyvcvdspeELRRHPRaitragqvkgngtRHEKddrrrirSRYVLGFDNRAKLAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1917 QDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQealskAQATLQEKEQRLLEQAELSCTLEAstatLQAT 1996
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS-----AEREIAELEAELERLDASSDDLAA----LEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1997 LDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEE-DLRQQDEQRQLLEKAVAQRSQENGIQE-KQSLEQ 2074
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERFAAALGDAVERElRENLEE 773

                          570       580
                   ....*....|....*....|..
gi 1958767515 2075 EKEEETRGLLESLKELQLTVAQ 2096
Cdd:COG4913    774 RIDALRARLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 1267-1974 1.03e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1267 DTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKME----AQNDRELLQASK 1342
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEearkAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1343 EKLSAQVEHLQACVTEARAQASAAGV---------LEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQE 1413
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEevrkaeelrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1414 NLTLLAQTLSNREREVETLQAEVQELEKQREMQKAAlELLSLDLKKRSREVDLQQEQIQELEQCRSvlehlpmavqEREQ 1493
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEKKKADEAKKAEEKKKA----------DEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1494 KLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLgtlECLALELEESHRKVEGQQKVITELEG 1573
Cdd:PTZ00121  1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1574 QRELQRVALthltlDLEERSQELQTQSSQLHELENHSTRlAKELQERDQEVmsqrQQIEELQKQKEQltqdlERKGQELV 1653
Cdd:PTZ00121  1386 KAEEKKKAD-----EAKKKAEEDKKKADELKKAAAAKKK-ADEAKKKAEEK----KKADEAKKKAEE-----AKKADEAK 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1654 LQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLilRDKEKEVECQ 1733
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA--EEAKKADEAK 1528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1734 QERIQELQEHMGQLEQQLQGLHRKVGETsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEA 1813
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEE---LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1814 LRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 1893
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1894 TvlalQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKE 1973
Cdd:PTZ00121  1686 D----EKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757


                   .
gi 1958767515 1974 Q 1974
Cdd:PTZ00121  1758 K 1758
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1428-1979 1.61e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1428 EVETLQAEVQELEK-QREMQKAA--LELLSlDLKKRSREVDLQQEQIQELEQCRSVLEHlpmavQEREQKLSVQRDQIRE 1504
Cdd:COG4913    226 AADALVEHFDDLERaHEALEDAReqIELLE-PIRELAERYAAARERLAELEYLRAALRL-----WFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1505 LENDR---EAQRTALEHQLLDLEQKAQVIESQR-----GQIQDLKKQLGTLECLALELEESHRKVEGQQKVI-----TEL 1571
Cdd:COG4913    300 LRAELarlEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAALglplpASA 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1572 EGQRELQRVALTHLtldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQI----EELQKQKEQLTQDLER 1647
Cdd:COG4913    380 EEFAALRAEAAALL----EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1648 KGQELVLQKERIQVLEDQ-----------RTLQTKIL--EEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPsKAQRG 1714
Cdd:COG4913    456 DEAELPFVGELIEVRPEEerwrgaiervlGGFALTLLvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERP-RLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1715 SLEHlKLILRDKEKEvecqqeriQELQEHMGQleqqlQGLHRKVGETSLLLTHREQETATLQ----QRLQEAKEQGELRE 1790
Cdd:COG4913    535 SLAG-KLDFKPHPFR--------AWLEAELGR-----RFDYVCVDSPEELRRHPRAITRAGQvkgnGTRHEKDDRRRIRS 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1791 QVLQGQleEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE--QAHVTLKERQGELEEHRGQVQRLQEE-- 1866
Cdd:COG4913    601 RYVLGF--DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAEle 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1867 -LIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEaEARTLQDSWLQAQATLAEQEQELEALRAENQYSR 1945
Cdd:COG4913    679 rLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLEERFAA 757

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1958767515 1946 QQEEAAFGQ-AEALQEALSKAQATLQEKEQRLLEQ 1979
Cdd:COG4913    758 ALGDAVERElRENLEERIDALRARLNRAEEELERA 792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1278-2128 2.03e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 2.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1278 ELQDLQRQLSQSQE--EKSKWEgkqnsleselrdLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQvehLQAC 1355
Cdd:pfam15921   86 QVKDLQRRLNESNElhEKQKFY------------LRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ---LQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1356 VTEARAqasaAGVLEEDLrtarsalkLKNEEIESERERAQALQEQGelkvaqgkALQENLTLLaqtlsnrereVETLQAE 1435
Cdd:pfam15921  151 VHELEA----AKCLKEDM--------LEDSNTQIEQLRKMMLSHEG--------VLQEIRSIL----------VDFEEAS 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1436 VQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELE-QCRSVLEHLPMAVQER-EQKLSVQRDQIRELENDREAQR 1513
Cdd:pfam15921  201 GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIfPVEDQLEALKSESQNKiELLLQQHQDRIEQLISEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1514 TALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLAleleeshrkvegqqkvITELEGQRELQRVALTHLTLDLEERS 1593
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ----------------LSDLESTVSQLRSELREAKRMYEDKI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1594 QELQTQssqlheLENHSTRLAKELQERDQevmsQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRT------ 1667
Cdd:pfam15921  345 EELEKQ------LVLANSELTEARTERDQ----FSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTgnsiti 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1668 --LQTKILEEDLEQIKHSLRERGQELASQWQLMQERAE-DGKSPSKAQRGSL----EHLKLILRDKEKEVECQQERIQEL 1740
Cdd:pfam15921  415 dhLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAiQGKNESLEKVSSLtaqlESTKEMLRKVVEELTAKKMTLESS 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1741 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVlQGQLEEAQRALAQRDHELEALRQEQQQ 1820
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNV-QTECEALKLQMAEKDKVIEILRQQIEN 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1821 TRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRlqeelivEGRQVRALEEVLGDLRAESrehEKTVLALQQ 1900
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDK-------KDAKIRELEARVSDLELEK---VKLVNAGSE 643

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1901 RCaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFG----QAEALQEALSKAQATLQEKEQRL 1976
Cdd:pfam15921  644 RL-RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmQLKSAQSELEQTRNTLKSMEGSD 722

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1977 LEQAELSCTLEASTATLQATLDTCQARARQLEEALrvregeiqTQALQHQEAMQHLQQELCQKEEDLrqQDEQRQLLEKA 2056
Cdd:pfam15921  723 GHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM--------TNANKEKHFLKEEKNKLSQELSTV--ATEKNKMAGEL 792

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767515 2057 VAQRSQENGIQEKQSleqEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKP 2128
Cdd:pfam15921  793 EVLRSQERRLKEKVA---NMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKP 861
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1631-1976 3.51e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 3.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1631 IEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTLQTKILEEDLEQIKH--SLRERGQELAsQWQLMQERaedgksp 1708
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENI----ERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYE-GYELLKEK------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1709 sKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKV----GETSLLLTHREQETATLQQRLQEAKE 1784
Cdd:TIGR02169  233 -EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1785 QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQ 1864
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1865 EELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartLQDSWLQAQATLAEQEQELEALRAENQYS 1944
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958767515 1945 RQQEEAAFGQAEALQEALSKAQATLQEKEQRL 1976
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1657-2114 4.22e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1657 ERIQVLEDQRTLQTKILEEDLEQikhslRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER 1736
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQ-----REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1737 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQgelreqvlqgqLEEAQRALAQRDHELEALRQ 1816
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR-----------LEECRVAAQAHNEEAESLRE 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1817 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRaESREHEKTVL 1896
Cdd:PRK02224   350 DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR-EERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1897 ALQQRCAEQAQEHEAEARTLQDSWLQAQ-----------ATLAEQEQELEALRAENQYSRQQEEAAFGQAEALqEALSKA 1965
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGKCPEcgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1966 QATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQH---LQQELCQKEED 2042
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKER 587

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767515 2043 LRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRgllESLKELQLTVAQKEEEILMLREAQQRQNQE 2114
Cdd:PRK02224   588 IESLERIRTLLAAIADAEDEIERLREKREALAELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKE 656
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1490-2216 4.24e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1490 EREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQ-IQDLKKQLGTLECLALELEESHRKVEGQQKVI 1568
Cdd:pfam02463  195 LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKEN 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1569 TELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErk 1648
Cdd:pfam02463  275 KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE-- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1649 gqelvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGS---LEHLKLILRD 1725
Cdd:pfam02463  353 -----AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELArqlEDLLKEEKKE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1726 KEKEVECQQERIQELQEHMGQLEQQLQglhrKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALA 1805
Cdd:pfam02463  428 ELEILEEEEESIELKQGKLTEEKEELE----KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1806 QRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRgqvqrlqEELIVEGRQVRALEEVLGDLR 1885
Cdd:pfam02463  504 KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA-------TADEVEERQKLVRALTELPLG 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1886 AESREHEKTVLalqqRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENqySRQQEEAAFGQAEALQEALSKA 1965
Cdd:pfam02463  577 ARKLRLLIPKL----KLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI--LKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1966 QATLQEKeqrLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQ 2045
Cdd:pfam02463  651 GVSLEEG---LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2046 QDEQRQLLEKAVAQRSQENGIQEKqslEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPA 2125
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2126 EKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLS 2205
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730
                   ....*....|.
gi 1958767515 2206 RQALEEQQSRG 2216
Cdd:pfam02463  885 KDELESKEEKE 895
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1796-2022 4.43e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 4.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAE---SREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAF 1952
Cdd:COG4942    101 AQKEELAELLRAlyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1953 GQAEALQEALSKAQAtlqekeqrllEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQA 2022
Cdd:COG4942    181 AELEEERAALEALKA----------ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PTZ00121 PTZ00121
MAEBL; Provisional
 1370-2092 4.53e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1370 EEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAA 1449
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1450 lELLSLDLKKRSREVDLQQEQIQEleqcrsvlEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQV 1529
Cdd:PTZ00121  1174 -DAKKAEAARKAEEVRKAEELRKA--------EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1530 IESQRGQIQDLKKQlgtlECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELEnh 1609
Cdd:PTZ00121  1245 AEEERNNEEIRKFE----EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-- 1318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1610 stRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEdlEQIKHSLRERGQ 1689
Cdd:PTZ00121  1319 --EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1690 ELASQWQLMQERAEDGKSPSKAQRGSLEhlkliLRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHRE 1769
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADE-----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1770 QETATLQQRLQEAKEQGELREQVLQGQ--LEEAQRALAQRDHELEALRQEQ----QQTRGQEESMK-------------- 1829
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEakkaDEAKKAEEAKKadeakkaeekkkad 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1830 --QKTSALQAALEQAHVTLKERQgelEEHRGQVQRLQEELivegrqvRALEEVLGDLRAESREHEKTVLALQQRCAEQAQ 1907
Cdd:PTZ00121  1550 elKKAEELKKAEEKKKAEEAKKA---EEDKNMALRKAEEA-------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1908 EHEAEARTLQDswLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLE 1987
Cdd:PTZ00121  1620 IKAEELKKAEE--EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1988 ASTATLQATLDTCQARARQLEEALRVREGEIQTQAlqhqeamqhlqqelcqkEEDLRQQDEQRQLLEKAVAQRSQENGIQ 2067
Cdd:PTZ00121  1698 AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-----------------EEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760

                          730       740
                   ....*....|....*....|....*
gi 1958767515 2068 EKQSLEQEKEEETRGLLESLKELQL 2092
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEEL 1785
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1291-2166 8.32e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 8.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1291 EEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElQKMEAQNDRELLQASKEKLsAQVEHLQACVTEARaqasaagVLE 1370
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAK-KALEYYQLKEKLELEEEYL-LYLDYLKLNEERID-------LLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1371 EDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAAL 1450
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1451 ELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVI 1530
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1531 ESQRGQIQDLKKQLGTLECLALELEEShrKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHS 1610
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELE--ILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1611 TRLAKELQERDQEVMSQRQQIEELQKQKEQLtqDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQE 1690
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVL--LALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1691 LASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQ 1770
Cdd:pfam02463  560 VEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1771 ETATLQQRLQEAKEQGELReqvlqGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQ 1850
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGL-----AEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1851 GELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHE-KTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAE 1929
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRlKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1930 QEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEE 2009
Cdd:pfam02463  795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLL 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2010 ALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEK---------QSLEQEKEEET 2080
Cdd:pfam02463  875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEeepeellleEADEKEKEENN 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2081 RGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHR---SFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWR 2157
Cdd:pfam02463  955 KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELekeRLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWN 1034


                   ....*....
gi 1958767515 2158 EKAQGLALS 2166
Cdd:pfam02463 1035 KVFFYLELG 1043
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1491-1831 9.16e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.36  E-value: 9.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1491 REQKLSVQRDQIRELEN-DREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGqqkvIT 1569
Cdd:pfam17380  279 QHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER----IR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1570 ELEGQRELQRValthltldleeRSQELQTQSSQLHELEnhstRLAKELQERDQEVmsqRQQIEELQKQKeQLTQDLERKG 1649
Cdd:pfam17380  355 QEERKRELERI-----------RQEEIAMEISRMRELE----RLQMERQQKNERV---RQELEAARKVK-ILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1650 QELVLQKERIQV-LEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRgslehlklilRDKEK 1728
Cdd:pfam17380  416 QQQKVEMEQIRAeQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELE----------KEKRD 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1729 EVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRD 1808
Cdd:pfam17380  486 RKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEER 565

                          330       340
                   ....*....|....*....|...
gi 1958767515 1809 HELEALRQEQQQTRGQEESMKQK 1831
Cdd:pfam17380  566 SRLEAMEREREMMRQIVESEKAR 588
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1225-1757 9.80e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 9.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1225 LTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQ-EEKSKWEGKQNSL 1303
Cdd:COG4913    271 LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERL 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1304 ESELRDLHETMASLQSRLRQAELQkmeaqndrelLQASKEKLSAQVEHLQACVTEARAQASAagvLEEDLRTARSALKLK 1383
Cdd:COG4913    351 ERELEERERRRARLEALLAALGLP----------LPASAEEFAALRAEAAALLEALEEELEA---LEEALAEAEAALRDL 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1384 NEEIESERERAQALQEQgelKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKA--------ALELL-- 1453
Cdd:COG4913    418 RRELRELEAEIASLERR---KSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfALTLLvp 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1454 SLDLKKRSREVDLQQEQIqeleqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLL------------ 1521
Cdd:COG4913    495 PEHYAAALRWVNRLHLRG------RLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGrrfdyvcvdspe 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1522 DLEQKAQVIeSQRGQIqdlkKQLGTLECLALELEESHRKVEGQ--QKVITELEGQRELQRVALThltlDLEERSQELQTQ 1599
Cdd:COG4913    569 ELRRHPRAI-TRAGQV----KGNGTRHEKDDRRRIRSRYVLGFdnRAKLAALEAELAELEEELA----EAEERLEALEAE 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1600 SSQLHELENHSTRLAkELQERDQEVMSQRQQIEELQKQKEQLTQ---DLERKGQELVLQKERIQVLEDQRT-LQTKI--L 1673
Cdd:COG4913    640 LDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDeLKGEIgrL 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1674 EEDLEQIkhslrergQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQ-QERIQELQEHMGQLEQQLQ 1752
Cdd:COG4913    719 EKELEQA--------EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDALRARLNRAEEELE 790


                   ....*
gi 1958767515 1753 GLHRK 1757
Cdd:COG4913    791 RAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1568-2102 1.04e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1568 ITELEGQRELQRVALTHLTLDL---EERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 1644
Cdd:PRK02224   222 IERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1645 LERKGQELVLQKERIQVLEDQRT-LQTKILEEDLEQIKH-----SLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEH 1718
Cdd:PRK02224   302 AGLDDADAEAVEARREELEDRDEeLRDRLEECRVAAQAHneeaeSLREDADDLEERAEELREEAAELESELEEAREAVED 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1719 LKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQ-L 1797
Cdd:PRK02224   382 RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQpV 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1798 EEAQRA--LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAaleqahvtLKERQGELEEHRGQVQRLQEELIVEGRQVR 1875
Cdd:PRK02224   462 EGSPHVetIEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAESREHEktvlalqqrcaEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQysrqqeeaAFGQA 1955
Cdd:PRK02224   534 EKRERAEELRERAAELE-----------AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE--------SLERI 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQEKEQRLLEQAELSctleastATLQATLDTCQARARQLEEAlrVREGEIQTQALQHQEAMQHLQQe 2035
Cdd:PRK02224   595 RTLLAAIADAEDEIERLREKREALAELN-------DERRERLAEKRERKRELEAE--FDEARIEEAREDKERAEEYLEQ- 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2036 lcqKEEDLRQQDEQRQLLEKAVAqrSQENGIQEKQSLEQEKE--EETRGLLESLK------------------------- 2088
Cdd:PRK02224   665 ---VEEKLDELREERDDLQAEIG--AVENELEELEELRERREalENRVEALEALYdeaeelesmygdlraelrqrnvetl 739

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1958767515 2089 ------------------------ELQLTVAQKEEEIL 2102
Cdd:PRK02224   740 ermlnetfdlvyqndayshieldgEYELTVYQKDGEPL 777
PTZ00121 PTZ00121
MAEBL; Provisional
 250-810 1.40e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.99  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  250 AKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKAlRGTMEILETNHAELMEHEASL 329
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA-DEAKKAEEKKKADEAKKKAEE 1313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  330 SRNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDlsqfDSQDPNKALTLVHSVLTRRQQAVQDLRQQ 409
Cdd:PTZ00121  1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE----AAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  410 LSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVD-LQGEVDSLSKERELLQTArgELQQQLEVLEQEAW 488
Cdd:PTZ00121  1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADeAKKKAEEAKKADEAKKKA--EEAKKAEEAKKKAE 1467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  489 RLRRVNVELQLQGDSAQGEKLEQ--QEELHLAVRERERLQETLVGLEAKQSESLSELIALREAlESSRLAGELLKQEQEE 566
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA-EEAKKADEAKKAEEKK 1546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  567 VAAALARAEqsivELSSSENSLKAEVADlRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVE----AAEQLRS 642
Cdd:PTZ00121  1547 KADELKKAE----ELKKAEEKKKAEEAK-KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeakkAEEAKIK 1621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  643 ALQVDLAEAERSREALWEEKTHLET----QLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDA 718
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKkkaeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  719 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQvlglrsaKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTI 798
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED-------KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                          570
                   ....*....|..
gi 1958767515  799 IQAKEVIQGEVK 810
Cdd:PTZ00121  1775 KEKEAVIEEELD 1786
mukB PRK04863
chromosome partition protein MukB;
1612-2007 1.42e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.19  E-value: 1.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1612 RLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERiqvledqrtlqTKILEEDLEQIKHSLrergqel 1691
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEA-----------ESDLEQDYQAASDHL------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1692 asqwQLMQERAEDGKSPSKAQrGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLThrEQE 1771
Cdd:PRK04863   338 ----NLVQTALRQQEKIERYQ-ADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALD--VQQ 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1772 TATLQ-----QRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAAL------- 1839
Cdd:PRK04863   411 TRAIQyqqavQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRkiagevs 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1840 -EQAHVTLKERQGELEEHRGQVQRLQE------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAE 1912
Cdd:PRK04863   491 rSEAWDVARELLRRLREQRHLAEQLQQlrmrlsELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQ----LQEELEAR 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1913 ARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEE---AAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEAS 1989
Cdd:PRK04863   567 LESLSESVSEARERRMALRQQLEQLQARIQRLAARAPawlAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVE 646

                          410
                   ....*....|....*...
gi 1958767515 1990 TATLQATLDTCQARARQL 2007
Cdd:PRK04863   647 RDELAARKQALDEEIERL 664
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1248-1940 2.00e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.51  E-value: 2.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1248 QQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQ 1327
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1328 KMEAQNDR----ELLQASKEKLSAQVEHLQACVTEAR-AQASAAGVLE--EDLRTARSALKL--KNEEIESERERAQALQ 1398
Cdd:TIGR00606  428 ADEIRDEKkglgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRILEldQELRKAERELSKaeKNSLTETLKKEVKSLQ 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1399 -EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSL--DLKKRSREVDLQQEQIQELE 1475
Cdd:TIGR00606  508 nEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgYFPNKKQLEDWLHSKSKEIN 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1476 QCRSVLEHLPMAVQEREQklsvQRDQIRELENDREAQRTALEHQLLDL---EQKAQVIESQRGQIQDLKKQLGTLECLAL 1552
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQ----NKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAMLAGATA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1553 ELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERsqeLQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIE 1632
Cdd:TIGR00606  664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSK---LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIID 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1633 ELQKQKEQLTQDLERKGQElvLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQ 1712
Cdd:TIGR00606  741 LKEKEIPELRNKLQKVNRD--IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGS 818

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1713 RG--SLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslLLTHREQETATLQQRlQEAKEQGELRE 1790
Cdd:TIGR00606  819 DLdrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE---LKSEKLQIGTNLQRR-QQFEEQLVELS 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1791 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEelive 1870
Cdd:TIGR00606  895 TEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKD----- 969

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1871 gRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEarTLQDSWLQAQATLAEQEQELEALRAE 1940
Cdd:TIGR00606  970 -DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ--KIQERWLQDNLTLRKRENELKEVEEE 1036
mukB PRK04863
chromosome partition protein MukB;
1901-2215 2.17e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1901 RCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSrQQEEAAFGQ--------------AEALQEALSKAQ 1966
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAEL-NEAESDLEQdyqaasdhlnlvqtALRQQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1967 ATLQEKEQRLLEQAELSCT---------------------LEASTATLQATLDTCQARARQLEEALRVRE---------- 2015
Cdd:PRK04863   355 ADLEELEERLEEQNEVVEEadeqqeenearaeaaeeevdeLKSQLADYQQALDVQQTRAIQYQQAVQALErakqlcglpd 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2016 ----------GEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEE------ 2079
Cdd:PRK04863   435 ltadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQrhlaeq 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2080 TRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPS--------------HRSFPAEKPSLQLLLAQQDLERLQNA 2145
Cdd:PRK04863   515 LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDeleqlqeelearleSLSESVSEARERRMALRQQLEQLQAR 594

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2146 LRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAsVLERESEQQRLQEELVLSRQALEEQQSR 2215
Cdd:PRK04863   595 IQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQ-LLERERELTVERDELAARKQALDEEIER 663
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 432-1097 2.27e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  432 KALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVL-EQEAWRLRRVNVELQLQGDSAQG---E 507
Cdd:TIGR02169  233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERsiaE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  508 KLEQQEELHLAVR----ERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARA-------EQ 576
Cdd:TIGR02169  313 KERELEDAEERLAkleaEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETrdelkdyRE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  577 SIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSRE 656
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  657 ALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAG------- 729
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAgnrlnnv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  730 --------QEKEALVRERAALEV------RLQAVERDRQDLAE----------------------QVLG-------LRSA 766
Cdd:TIGR02169  553 vveddavaKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEdgvigfavdlvefdpkyepafkYVFGdtlvvedIEAA 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  767 KEQ--------LEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDT---ERSHAEQERDAvARQLA 835
Cdd:TIGR02169  633 RRLmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlqsELRRIENRLDE-LSQEL 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  836 QAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQkLDKTLETLERERTELEMKLREQHTETEALRAQREE-ERTQAD 914
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSH 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  915 SALYQMQLET---EKERVSL----------LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQEL 981
Cdd:TIGR02169  791 SRIPEIQAELsklEEEVSRIearlreieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  982 KE---AIQQHRDDLAAFQKDKIDLQKQVEDLTS---------QLVTHNDSQRLVK--------QEIEEKVREAQECS--- 1038
Cdd:TIGR02169  871 EEleaALRDLESRLGDLKKERDELEAQLRELERkieeleaqiEKKRKRLSELKAKlealeeelSEIEDPKGEDEEIPeee 950

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767515 1039 ----RIQKELEK-EKASLTLSLV---------EKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQV 1097
Cdd:TIGR02169  951 lsleDVQAELQRvEEEIRALEPVnmlaiqeyeEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 312-608 2.69e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 2.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  312 MEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALAsvEEEDTVTQTPGSENSLQSDYNDLSQF--DSQDPNKAL 389
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK--ELEELSRQISALRKDLARLEAEVEQLeeRIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  390 TLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELL 469
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  470 QTARGELQQQLEVLEQEAWRLRRVNVELQLQGD-------SAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSE 542
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEeleseleALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515  543 LIALREALESSRLAGELLKQEQEEVAAALAR--------AEQSIVELSSSENSLKAEVADLRAAAVKLGALNEA 608
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeAEALENKIEDDEEEARRRLKRLENKIKELGPVNLA 990
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1722-2297 2.98e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1722 ILRDKEKEVECQQERIQELQEHmgQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGElreqvlqgQLEEAQ 1801
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE--------EHEERR 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1802 RALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVL 1881
Cdd:PRK02224   251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1882 GDLRAESREHEKTVLALQQRCA---EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAEnqysrqqeeaafgqAEAL 1958
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADdleERAEELREEAAELESELEEAREAVEDRREEIEELEEE--------------IEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1959 QEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQAR---ARQLEEALRVREGEIQTQALQHQEAMQHLQQE 2035
Cdd:PRK02224   397 RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERveeAEALLEAGKCPECGQPVEGSPHVETIEEDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2036 LCQKEEDLRQQDEQRQLLEKAVAQrsqengiqEKQSLEQEKEEETrgLLESLKELQLTVAQKEEEILMLREAQQRQNQEA 2115
Cdd:PRK02224   477 VEELEAELEDLEEEVEEVEERLER--------AEDLVEAEDRIER--LEERREDLEELIAERRETIEEKRERAEELRERA 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2116 SspshrsfpaekpslqllLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMfLQASVLERESEQ 2195
Cdd:PRK02224   547 A-----------------ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRT-LLAAIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2196 QRLQEElvlsRQALEEQQS-RGPHSSSRADQGPKAGQDTEPGEVIEAEpspgvGEKEQLRQRLERLQQAVAELEVDRSKL 2274
Cdd:PRK02224   609 ERLREK----REALAELNDeRRERLAEKRERKRELEAEFDEARIEEAR-----EDKERAEEYLEQVEEKLDELREERDDL 679

                          570       580
                   ....*....|....*....|...
gi 1958767515 2275 QCHNAQLRTTLEQVERERRKLKR 2297
Cdd:PRK02224   680 QAEIGAVENELEELEELRERREA 702
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 767-1333 3.12e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 3.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  767 KEQLEGNLFEAQQQnsvIQVTKSQLEVQIQTIIQAKEViqgEVKCLKLELDTERSHAEQERDAVARQLAQAEQEgQAALE 846
Cdd:pfam15921  244 EDQLEALKSESQNK---IELLLQQHQDRIEQLISEHEV---EITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMYM 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  847 RQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTEL-EMKLREQHTETEALRAQREEERTQADSALYQMQLETE 925
Cdd:pfam15921  317 RQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELtEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  926 KERVSLLE--------TLLQTQKELADASQQLERLRQDMKVQKlkeQETTGMLQAQLrGAQQELKEAIQQHRDDLAAFQK 997
Cdd:pfam15921  397 KEQNKRLWdrdtgnsiTIDHLRRELDDRNMEVQRLEALLKAMK---SECQGQMERQM-AAIQGKNESLEKVSSLTAQLES 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  998 DKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSL---------------VEKEKRL 1062
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLqelqhlknegdhlrnVQTECEA 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1063 LVLQEADSVRQRELvsLRQDIQE-----AQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLW 1137
Cdd:pfam15921  553 LKLQMAEKDKVIEI--LRQQIENmtqlvGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1138 AQE----AKAAQLQLQ-LRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACErrpELRGGGDSVPTPWGSDPDQ 1212
Cdd:pfam15921  631 ELEkvklVNAGSERLRaVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE---EMETTTNKLKMQLKSAQSE 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1213 NGASRLLKRGPLLTALSAEAVALALQKlhqDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEE 1292
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQK---QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1958767515 1293 KSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQN 1333
Cdd:pfam15921  785 KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1500-2015 3.30e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 3.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1500 DQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQ-RELQ 1578
Cdd:PRK03918   210 NEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElKELK 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1579 RVALTHLTLdlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKER 1658
Cdd:PRK03918   290 EKAEEYIKL--SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1659 IQVLEDQRTLQTKI---------------------LEEDLEQIKHSLRERGQELASQWQLMQE-RAEDGKSPSKAQRGSL 1716
Cdd:PRK03918   368 KAKKEELERLKKRLtgltpeklekeleelekakeeIEEEISKITARIGELKKEIKELKKAIEElKKAKGKCPVCGRELTE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1717 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQetatlqqrlqeAKEQGELREQVLQGQ 1796
Cdd:PRK03918   448 EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKEL-----------AEQLKELEEKLKKYN 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1797 LEEAQRAlaqrDHELEALRQEQQQTRGQEESMKQKTSALQaALEQAHVTLKERQGELEEHRGQVQRLQEELIVEgrQVRA 1876
Cdd:PRK03918   517 LEELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGFE--SVEE 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1877 LEEVLGDLRAESREHEKTVLALQqrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAE-NQYSRQQEEAAFGQA 1955
Cdd:PRK03918   590 LEERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKRLEELRKElEELEKKYSEEEYEEL 664

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQEKEQRLLEQAElscTLEASTATLQATLDTCQARARQLEEALRVRE 2015
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRRE---EIKKTLEKLKEELEEREKAKKELEKLEKALE 721
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1237-1841 3.84e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 3.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1237 LQKLHQDLWKAQQARDDLR------DQVQKLVQRLTDTEAQKSQVhsELQDLQRQLSQSQEEKSKWEGKQNSLESELRDL 1310
Cdd:COG4913    237 LERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1311 HETMASLQSRLRQAELQKMEAQNDRellqasKEKLSAQVEHLQAcvtEARAQASAAGVLEEDLRTARSALKLKNEEIESE 1390
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDR------LEQLEREIERLER---ELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1391 RERAQALQEQGElkvAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQR----EMQKAALELLSLDLKKRSREVdl 1466
Cdd:COG4913    386 RAEAAALLEALE---EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAEL-- 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1467 qqeqiqeleqcRSVLEHLPMAVQEREQKLSVQRdqirELENdreaQRTALehqLLDLEQKAQVIE-------SQRGQIQD 1539
Cdd:COG4913    461 -----------PFVGELIEVRPEEERWRGAIER----VLGG----FALTL---LVPPEHYAAALRwvnrlhlRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1540 LKKQLGTLECLALELEESHRKVEGQQKVITElEGQRELQRVALTHLTLDLEERSQELQ--TQSSQLHeleNHSTRLAKEL 1617
Cdd:COG4913    519 VRTGLPDPERPRLDPDSLAGKLDFKPHPFRA-WLEAELGRRFDYVCVDSPEELRRHPRaiTRAGQVK---GNGTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1618 QERDQEV----MSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqELAs 1693
Cdd:COG4913    595 RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1694 qwQLMQERAEDGKSPSKaqrgsLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthrEQETA 1773
Cdd:COG4913    672 --ELEAELERLDASSDD-----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA--------------EEELD 730

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767515 1774 TLQQRLQEAkeqGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQ 1841
Cdd:COG4913    731 ELQDRLEAA---EDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1252-1867 3.94e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 3.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1252 DDLRDQVQKLVQRLTDTEaqksQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEA 1331
Cdd:PRK03918   144 DESREKVVRQILGLDDYE----NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1332 QNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQgELKVAQGKAL 1411
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1412 QENLTLLAQTLSNREREVETLQAEVQELEKQREmqkaalellslDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQER 1491
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIK-----------ELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1492 EQKLsVQRDQIRELENDREAQRtaLEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV---- 1567
Cdd:PRK03918   368 KAKK-EELERLKKRLTGLTPEK--LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgre 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1568 ITELEGQRELQRvalthLTLDLEERSQELQTQSSQLHELENHSTRLAKELqERDQEVMSQRQQIEELQKQKEQLT----Q 1643
Cdd:PRK03918   445 LTEEHRKELLEE-----YTAELKRIEKELKEIEEKERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKkynlE 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1644 DLERKGQELVLQKERIQVLE-DQRTLQTKI-----LEEDLEQIKHSLRERGQELASqwqLMQERAEDGKSPSKAQRGSLE 1717
Cdd:PRK03918   519 ELEKKAEEYEKLKEKLIKLKgEIKSLKKELekleeLKKKLAELEKKLDELEEELAE---LLKELEELGFESVEELEERLK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1718 HLK------LILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtslllthreqetatLQQRLQEA-KEQGELRE 1790
Cdd:PRK03918   596 ELEpfyneyLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE--------------LRKELEELeKKYSEEEY 661

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1791 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQgELEEHRGQVQRLQEEL 1867
Cdd:PRK03918   662 EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE-RVEELREKVKKYKALL 737
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1251-1919 3.98e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1251 RDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELR---------------DLHETMA 1315
Cdd:pfam15921  305 QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARterdqfsqesgnlddQLQKLLA 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1316 SLQSRLRQAELQKMEAQN--DREL--------LQASKEKLSAQVEHLQACVTEARAQASaaGVLEEDLrtarSALKLKNE 1385
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRlwDRDTgnsitidhLRRELDDRNMEVQRLEALLKAMKSECQ--GQMERQM----AAIQGKNE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1386 EIEsereRAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKqremqkaALELLSLDLKKRSREVD 1465
Cdd:pfam15921  459 SLE----KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER-------AIEATNAEITKLRSRVD 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1466 lqqeqiqeleqcrsvlehlpMAVQEReQKLSVQRDQIRELENDREAQRtalehqlLDLEQKAQVIESQRGQIQDLKKQLG 1545
Cdd:pfam15921  528 --------------------LKLQEL-QHLKNEGDHLRNVQTECEALK-------LQMAEKDKVIEILRQQIENMTQLVG 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1546 ----TLECLALELEESHRKVEGQQKVITELEGQRELQRVALThltlDLEERSQELQTQSSQLHELENHSTRLAKEL-QER 1620
Cdd:pfam15921  580 qhgrTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR----ELEARVSDLELEKVKLVNAGSERLRAVKDIkQER 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1621 DQ---EVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQvledqrtLQTKILEEDLEQIKHSLRERGQELASQWQL 1697
Cdd:pfam15921  656 DQllnEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK-------MQLKSAQSELEQTRNTLKSMEGSDGHAMKV 728

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1698 mqerAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGL----HRKVGETSLLLTHR---EQ 1770
Cdd:pfam15921  729 ----AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVatekNKMAGELEVLRSQErrlKE 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1771 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALrqeqqQTRGQEESMKQKTSALQ-AALEQAHVTLKER 1849
Cdd:pfam15921  805 KVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKEL-----QGPGYTSNSSMKPRLLQpASFTRTHSNVPSS 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1850 QGE---LEEHRGQVQRLQE-------ELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDS 1919
Cdd:pfam15921  880 QSTasfLSHHSRKTNALKEdptrdlkQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSS 959
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
665-1131 4.35e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 4.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  665 LETQLRKAEETgaELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALaragQEKEALVRERAALEV 744
Cdd:PRK02224   192 LKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR----EELETLEAEIEDLRE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  745 RLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAE 824
Cdd:PRK02224   266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  825 QERDAVARQLAQAE--QEGQAALERQKVAHEEEVNRLQEKWEKerallqqkLDKTLETLERERTELEMKLREQHTETEAL 902
Cdd:PRK02224   346 SLREDADDLEERAEelREEAAELESELEEAREAVEDRREEIEE--------LEEEIEELRERFGDAPVDLGNAEDFLEEL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  903 RAQREEERtqADSALYQMQLETEKERVSLLETLLQTQK-----------------------------ELADASQQLERLR 953
Cdd:PRK02224   418 REERDELR--EREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveeleaELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  954 QDM-KVQKLKEQETTgmlQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVR 1032
Cdd:PRK02224   496 ERLeRAEDLVEAEDR---IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1033 EAQECSRIQKELEKEKASLTlslvekekrllvlqeadsvRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFV 1112
Cdd:PRK02224   573 EVAELNSKLAELKERIESLE-------------------RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKR 633

                          490
                   ....*....|....*....
gi 1958767515 1113 AREAQLLEELEASRIAERQ 1131
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAR 652
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 786-1103 4.48e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 4.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  786 VTKSQLEVQIQTIIQAKEVIQGEVKCLKLE-LDTERSHAEQERDAVA----RQLAQAEQEGQAALERQKVAHEEEVNRLQ 860
Cdd:pfam17380  265 MTENEFLNQLLHIVQHQKAVSERQQQEKFEkMEQERLRQEKEEKAREverrRKLEEAEKARQAEMDRQAAIYAEQERMAM 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 EKWEKERALLQQKLDKTLETLERERTELEM-KLREQHTETEALRAQREEERTQADSALYQMQLETEKERvslleTLLQTQ 939
Cdd:pfam17380  345 ERERELERIRQEERKRELERIRQEEIAMEIsRMRELERLQMERQQKNERVRQELEAARKVKILEEERQR-----KIQQQK 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  940 KELADASQQLERLRQDmKVQKLKEQETTGMlqAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDltsQLVTHNDS 1019
Cdd:pfam17380  420 VEMEQIRAEQEEARQR-EVRRLEEERAREM--ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD---RKRAEEQR 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1020 QRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEAdsvRQRELVSLRQDIQEAQEGQRELGVQVEL 1099
Cdd:pfam17380  494 RKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER---RKQQEMEERRRIQEQMRKATEERSRLEA 570


                   ....
gi 1958767515 1100 LRQE 1103
Cdd:pfam17380  571 MERE 574
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 815-936 4.59e-06

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 52.01  E-value: 4.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  815 ELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQ--QKLDKTLETLERERTELEMKL 892
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEeiQELKEELEQRYGKIPELEKEL 494

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767515  893 REQHTETEALRAQREEERTQADSA----------LYQMqLETEKERVSLLETLL 936
Cdd:COG0542    495 AELEEELAELAPLLREEVTEEDIAevvsrwtgipVGKL-LEGEREKLLNLEEEL 547
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1253-1867 6.69e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 6.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1253 DLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAElqkmeaq 1332
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKE------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1333 NDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQ 1412
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1413 ENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDlqqeqiqeleqcrsvlehlpmavqERE 1492
Cdd:TIGR04523  232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIK------------------------ELE 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1493 QKLSVQRDQIRELENDREaqrtalehQLLDLEQKAQvIESQRGQIQDLKKQLGTLeclaleleeshrkvegqQKVITELE 1572
Cdd:TIGR04523  288 KQLNQLKSEISDLNNQKE--------QDWNKELKSE-LKNQEKKLEEIQNQISQN-----------------NKIISQLN 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1573 GQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL 1652
Cdd:TIGR04523  342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1653 VLQKERIQVLEDQRTLQTKILeEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVEC 1732
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEI-KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1733 QQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEqgELREQVLQGQLEEAQRALAQRDHELE 1812
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEIEELKQTQK 578

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 1813 ALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEEL 1867
Cdd:TIGR04523  579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 884-1117 7.74e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 7.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  884 ERTELEMKLREQHTETEALRAQREEERTQADSALYQMQlETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE 963
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  964 QETTGMLQAQLRGAQQelkeaiqQHRDDLAAFqkdkIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKE 1043
Cdd:COG4942    100 EAQKEELAELLRALYR-------LGRQPPLAL----LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 1044 LEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQ 1117
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 408-917 8.35e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 8.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  408 QQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDAL--------AGQTVDLQGEVDSLSKERELLQTA------- 472
Cdd:pfam12128  340 ETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRrskikeqnNRDIAGIKDKLAKIREARDRQLAVaeddlqa 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  473 -----RGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKlEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALR 547
Cdd:pfam12128  420 leselREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP-ELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  548 EALESSRLAGELLKQEQEEVAAALARAEQSIVELSSS-ENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQE 626
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTlLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGEL 578

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  627 NQ-SMCSRVEaaeqlrsalQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQE 705
Cdd:pfam12128  579 NLyGVKLDLK---------RIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALK 649

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  706 AATAQLQQLHQDAERQEEALARAGQEKEALVRER-AALEVRLQAVERDRQDLAEQVLGlrsakEQLEGNLFEAQQQNSVI 784
Cdd:pfam12128  650 NARLDLRRLFDEKQSEKDKKNKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKE-----QKREARTEKQAYWQVVE 724

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  785 QVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTER----------SHAEQERDAVARQLAQAEQEGQAALERQKVahee 854
Cdd:pfam12128  725 GALDAQLALLKAAIAARRSGAKAELKALETWYKRDLaslgvdpdviAKLKREIRTLERKIERIAVRRQEVLRYFDW---- 800

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767515  855 evnrLQEKWEKERallqQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSAL 917
Cdd:pfam12128  801 ----YQETWLQRR----PRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQ 855
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1355-1579 8.98e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1355 CVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQA 1434
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1435 EVQELEKQREMQKAALELLSLDLKKRSR----EVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDRE 1510
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1511 AQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQ-QKVITELEGQRELQR 1579
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEElEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 396-610 9.54e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 9.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  396 LTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGE 475
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  476 LQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRL 555
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515  556 AgelLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALA 610
Cdd:COG4942    182 E---LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1589-2298 9.58e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 9.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1589 LEERSQELQTQSSQLHELENHSTrLAKELQERDQEVMSQrqQIEELQKQKEQLTQDLERKGQELvlqkERIQVLEDQRTL 1668
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQA-LLKEKREYEGYELLK--EKEALERQKEAIERQLASLEEEL----EKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1669 QTKILEEDLEQIKHSLRERGQELASQwqlMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLE 1748
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLR---VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1749 QQLQGLHRKVGETSLLLTHREQETATLQQRLQE-AKEQGELREQV--LQGQLEEAQRALAQRDHELEALRQEQQQTRGQE 1825
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEvDKEFAETRDELkdYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1826 ESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLAL--QQRCA 1903
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeaQARAS 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1904 EQAQEHEAEARTLQDSWLQAQATLAEQeqeleALRAENQYSRQQEEAAFGQAEALQ-EALSKAQATLQEKEQRLL----- 1977
Cdd:TIGR02169  503 EERVRGGRAVEEVLKASIQGVHGTVAQ-----LGSVGERYATAIEVAAGNRLNNVVvEDDAVAKEAIELLKRRKAgratf 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1978 --------EQAELSCTLEASTATLQATLDTCQARAR--------------QLEEALR----VREGEIQTQALQHQEAMQH 2031
Cdd:TIGR02169  578 lplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvveDIEAARRlmgkYRMVTLEGELFEKSGAMTG 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2032 LQQELCQKEEDLRQQDEQRQLL--EKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLtvAQKEEEILMLREAQQ 2109
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPAELQRLreRLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE--IEKEIEQLEQEEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2110 RQNQEASSPSHRSFpaekpSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSK-----ASISSLQEIAMFL 2184
Cdd:TIGR02169  736 KERLEELEEDLSSL-----EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeiqAELSKLEEEVSRI 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2185 QASVLERESEQQRLQEELVLSRQALEEQQSRGPHSSSRADQgpkagqdtepgevIEAEPSPGVGEKEQLRQRLERLQQAV 2264
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS-------------IEKEIENLNGKKEELEEELEELEAAL 877

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1958767515 2265 AELEVDRSKLqchnaqlrttleqvERERRKLKRD 2298
Cdd:TIGR02169  878 RDLESRLGDL--------------KKERDELEAQ 897
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 931-1173 1.18e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  931 LLETLLQTQKELADASQQLERLRQDMKvQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLT 1010
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIA-ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1011 SQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASltlSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQ 1090
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPE---DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1091 RELGVQVELLRQEVKEKEadfvareaQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQA 1170
Cdd:COG4942    167 AELEAERAELEALLAELE--------EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ...
gi 1958767515 1171 QAQ 1173
Cdd:COG4942    239 AAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-1160 1.30e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  331 RNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQ------ 404
Cdd:TIGR02169  207 REKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlge 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  405 ----DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALagqtvdlQGEVDSLSKerellqtargelqqql 480
Cdd:TIGR02169  287 eeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL-------LAEIEELER---------------- 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  481 evlEQEAWRLRRVNVELQLQGDSAQGEKLEQqeelhlavrereRLQEtlvgLEAKQSESLSELIALREALESsrlagelL 560
Cdd:TIGR02169  344 ---EIEEERKRRDKLTEEYAELKEELEDLRA------------ELEE----VDKEFAETRDELKDYREKLEK-------L 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  561 KQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALdkvalnqqllqleqenqsmcsRVEAAEQL 640
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL---------------------EIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  641 RSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAER 720
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGER 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  721 QEEAL-ARAGQEKEALVRERAALEVRLQAVERDRQD-----------LAEQVLGLRSAKEQLEGNL-----FEAQQQNSV 783
Cdd:TIGR02169  537 YATAIeVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAvdlveFDPKYEPAF 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  784 IQVTKSQLEVQiqtIIQAKEVIQGEVKCLKLELDT-ERSHAEQ--ERDAVARQLAQAEQEGQaalerqkvahEEEVNRLQ 860
Cdd:TIGR02169  617 KYVFGDTLVVE---DIEAARRLMGKYRMVTLEGELfEKSGAMTggSRAPRGGILFSRSEPAE----------LQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  861 EKWEKERALLQQKLDKtletLERERTELEMKLREQHTETEALRAQREEertqadsalYQMQLETEKERVSLLETLLQ-TQ 939
Cdd:TIGR02169  684 EGLKRELSSLQSELRR----IENRLDELSQELSDASRKIGEIEKEIEQ---------LEQEEEKLKERLEELEEDLSsLE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  940 KELADASQQLERLR---QDMKVQKLKEQETTGMLQAQLRGAQ-QELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVT 1015
Cdd:TIGR02169  751 QEIENVKSELKELEariEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1016 HNDS-QRLVKQEIEEKVREAQECSRIQkELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELG 1094
Cdd:TIGR02169  831 LEKEiQELQEQRIDLKEQIKSIEKEIE-NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1095 VQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVraslwAQEAKAAQLQLQLRSTEAQLEAL 1160
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIP-----EEELSLEDVQAELQRVEEEIRAL 970
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1239-1686 1.36e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1239 KLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLqrqLSQSQEEKSKWEGKQNSLESELRDLHETMASLQ 1318
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL---KDEQNKIKKQLSEKQKELEQNNKKIKELEKQLN 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1319 SRlrQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQ 1398
Cdd:TIGR04523  292 QL--KSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1399 EQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCR 1478
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1479 SVLEhlpMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESH 1558
Cdd:TIGR04523  450 SVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1559 RKVEgqqKVITELEGQ-----RELQRVALTHLTLDLEERSQELQTQSSQLHE----LENHSTRLAKELQERDQEVMSQRQ 1629
Cdd:TIGR04523  527 EKLE---SEKKEKESKisdleDELNKDDFELKKENLEKEIDEKNKEIEELKQtqksLKKKQEEKQELIDQKEKEKKDLIK 603

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1630 QIEELQKQKEQLTQDLERKGQElvlqKERIQVLEDQRTLQTKILEEDLEQIKHSLRE 1686
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1386-2070 1.39e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1386 EIESERERAQALQEQGELKVAQGKALQENLT-LLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREV 1464
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEkELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1465 DLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQL 1544
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1545 GTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEV 1624
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1625 MSQR---------QQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQW 1695
Cdd:TIGR00618  435 LQQRyaelcaaaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1696 QLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQER--IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETA 1773
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkqRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1774 TLQQRLQEAKEQGELREQVLQGQLEEAQRALAqrDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEl 1853
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPEQD--LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1854 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQE 1933
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA----AREDALNQSLKE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1934 LEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRV 2013
Cdd:TIGR00618  748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767515 2014 REGEIQTQALQHQEAMQH-LQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQ 2070
Cdd:TIGR00618  828 QEEEQFLSRLEEKSATLGeITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1397-2101 1.44e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1397 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLqqeqiqeleq 1476
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKN---------- 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1477 crsvlehlpmavqeREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEE 1556
Cdd:TIGR04523  115 --------------DKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1557 SHRKVEGQQKVItelegqrELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQK 1636
Cdd:TIGR04523  181 EKLNIQKNIDKI-------KNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1637 QKEQLTQDLERKGQELvlqKERIQVLEDQRTLqTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsL 1716
Cdd:TIGR04523  254 QLNQLKDEQNKIKKQL---SEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDW--------------------N 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1717 EHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQ 1796
Cdd:TIGR04523  310 KELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1797 LEEAQRaLAQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 1876
Cdd:TIGR04523  383 KQEIKN-LESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1877 LEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAE 1956
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1957 ALQEALSKAQATLQEKEQRLleqaelsctleastatlqatldtcqaraRQLEEALRVREGEIQTQALQHQeaMQHLQQEL 2036
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKI----------------------------SDLEDELNKDDFELKKENLEKE--IDEKNKEI 570

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 2037 CQKEEDlrqqdeqrqllekavaQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI 2101
Cdd:TIGR04523  571 EELKQT----------------QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
PRK11281 PRK11281
mechanosensitive channel MscK;
1773-2095 1.54e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.68  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1773 ATLQQRLQEAKEQGELREQ--VLQGQLEEAQRALAQRD---HELEALRQEQQQTRGQEESMKQKTSALQAALEQ------ 1841
Cdd:PRK11281    39 ADVQAQLDALNKQKLLEAEdkLVQQDLEQTLALLDKIDrqkEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEetretl 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1842 AHVTLKERQGELEEHRGQVQRLQEELIVEGRQV--------RA-------------LEEVLGDLRAESREHEKTVLALQQ 1900
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLvslqtqpeRAqaalyansqrlqqIRNLLKGGKVGGKALRPSQRVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1901 rcAEQA--------QEHEAEARTLQDSWLQAQ-----ATLAEQEQELEALRAE-NQYSRQQEEAAFGQAEALQEALSKAQ 1966
Cdd:PRK11281   199 --AEQAllnaqndlQRKSLEGNTQLQDLLQKQrdyltARIQRLEHQLQLLQEAiNSKRLTLSEKTVQEAQSQDEAARIQA 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1967 ATLQEKE--------QRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEI--------QTQALQHQEAMQ 2030
Cdd:PRK11281   277 NPLVAQEleinlqlsQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLKGSLllsrilyqQQQALPSADLIE 356

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767515 2031 HL----------QQELCQKEEDLRQQDEqrqLLEKAVAQRSQENGIQEKQSLEQEKEEEtRGLLESL-KEL--QLTVA 2095
Cdd:PRK11281   357 GLadriadlrleQFEINQQRDALFQPDA---YIDKLEAGHKSEVTDEVRDALLQLLDER-RELLDQLnKQLnnQLNLA 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 700-928 1.55e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  700 AHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQ 779
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  780 QnsvIQVTKSQLEVQIQTIIQakeviQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRL 859
Cdd:COG4942     98 E---LEAQKEELAELLRALYR-----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515  860 QEKWEKERALL--QQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKER 928
Cdd:COG4942    170 EAERAELEALLaeLEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
428-967 2.49e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  428 EEEGKALRERLQKLTGERDalagqtvDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQlqgdsaqge 507
Cdd:PRK02224   198 EKEEKDLHERLNGLESELA-------ELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIE--------- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  508 klEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENS 587
Cdd:PRK02224   262 --DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  588 LKAEVADLRAAAVKLGALNEALaldkvalnqqllqlEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLET 667
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEEL--------------REEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  668 QLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQ-----QLHQDAERQE--EALARAGQEKEALVRERA 740
Cdd:PRK02224   406 DLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEGSPhvETIEEDRERVEELEAELE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  741 ALEVR-------------LQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQT---IIQAKEV 804
Cdd:PRK02224   486 DLEEEveeveerleraedLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEkreAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  805 IQGEVKCLKLELDTERSHAEQERDAVAR---QLAQAEQEGQAALE-RQKVAHEEEVN-----RLQEKWEKERALLQQKLD 875
Cdd:PRK02224   566 EAEEAREEVAELNSKLAELKERIESLERirtLLAAIADAEDEIERlREKREALAELNderreRLAEKRERKRELEAEFDE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  876 KTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQ-LETEKERVSLLETLLQTQKELADASQQLE---- 950
Cdd:PRK02224   646 ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEeLEELRERREALENRVEALEALYDEAEELEsmyg 725

                          570
                   ....*....|....*..
gi 1958767515  951 RLRQDMKVQKLKEQETT 967
Cdd:PRK02224   726 DLRAELRQRNVETLERM 742
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1762-2005 2.51e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1762 SLLLTHREQETATLQQRLQEAKEQGELREQVL---QGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAA 1838
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELaalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1839 LEQAHVTLKERQGELEEHRGQVQRLQE----ELIVEGRQVRALEEVLGDLRAESREhektvlalQQRCAEQAQEHEAEAR 1914
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPA--------RREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1915 TLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQ 1994
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243

                          250
                   ....*....|.
gi 1958767515 1995 ATLDTCQARAR 2005
Cdd:COG4942    244 PAAGFAALKGK 254
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 428-750 2.59e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  428 EEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGE 507
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  508 KLEQQEELHLAVRERERLQETLVgleakqseslseliALREALES--SRLAGELLKQ---EQEEVAAALARAEQSIVELS 582
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLH--------------KLEEALNDleARLSHSRIPEiqaELSKLEEEVSRIEARLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  583 SSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEaaeqlrsALQVDLAEAERSREALWEEK 662
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE-------ELEAALRDLESRLGDLKKER 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  663 THLETQLRKAEETGAELQAELRGAREEKEElkeklneahhQQEAATAQLQQLHQ--DAERQEEALARAGQEKEALVRERA 740
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKRLSE----------LKAKLEALEEELSEieDPKGEDEEIPEEELSLEDVQAELQ 961

                          330
                   ....*....|
gi 1958767515  741 ALEVRLQAVE 750
Cdd:TIGR02169  962 RVEEEIRALE 971
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1572-2057 2.65e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 2.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1572 EGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKG-- 1649
Cdd:COG4913    259 ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgd 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1650 --QELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKE 1727
Cdd:COG4913    339 rlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1728 KEVECQQERIQELQEHMGQLEQQLQGLhRKVGETSLLLTHREQ-------ETATLQQRLQEAKEqGELREQ-----VLQG 1795
Cdd:COG4913    419 RELRELEAEIASLERRKSNIPARLLAL-RDALAEALGLDEAELpfvgeliEVRPEEERWRGAIE-RVLGGFaltllVPPE 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRD-------HELEALRQEQQQTRGQEES----MKQKTSALQAALEQ-----AHVTLKERQGELEEHR-- 1857
Cdd:COG4913    497 HYAAALRWVNRLHlrgrlvyERVRTGLPDPERPRLDPDSlagkLDFKPHPFRAWLEAelgrrFDYVCVDSPEELRRHPra 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1858 ----GQV------------QRLQEELIV---EGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQD 1918
Cdd:COG4913    577 itraGQVkgngtrhekddrRRIRSRYVLgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY 656

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1919 SW-----LQAQATLAEQEQELEALRAENqysrqqeeaafGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATL 1993
Cdd:COG4913    657 SWdeidvASAEREIAELEAELERLDASS-----------DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 1994 QATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAV 2057
Cdd:COG4913    726 EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1626-2109 2.74e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1626 SQRQQIEELQKQKEQLTQDLERKGQELvlqKERIQVLEDQrtlqTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDG 1705
Cdd:TIGR00618  191 SLHGKAELLTLRSQLLTLCTPCMPDTY---HERKQVLEKE----LKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1706 KSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQ 1785
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1786 GELREQVLQGQLEeaqraLAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQE 1865
Cdd:TIGR00618  344 RRLLQTLHSQEIH-----IRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1866 ELIVEGRQVRA-LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 1944
Cdd:TIGR00618  419 FRDLQGQLAHAkKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1945 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 2024
Cdd:TIGR00618  499 LQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQC 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2025 HQEA-------MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQK 2097
Cdd:TIGR00618  579 DNRSkedipnlQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE 658

                          490
                   ....*....|..
gi 1958767515 2098 EEEILMLREAQQ 2109
Cdd:TIGR00618  659 RVREHALSIRVL 670
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1733-2208 2.94e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1733 QQERIQELQEHMGQLEQQLQGLHRKVGETSL-LLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHE- 1810
Cdd:COG4913    260 LAERYAAARERLAELEYLRAALRLWFAQRRLeLLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDr 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1811 LEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVR----ALEEVLGDLRA 1886
Cdd:COG4913    340 LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1887 ESREHEKTVLALQQR--------------CAEQAQEHEAEA---------RTLQDSWLQA-------QAT--LAEQEQEL 1934
Cdd:COG4913    420 ELRELEAEIASLERRksniparllalrdaLAEALGLDEAELpfvgelievRPEEERWRGAiervlggFALtlLVPPEHYA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1935 EALRAENQYSRQQ----EEAAFGQAEALQEALSKAqaTLQEK------------EQRLLEQAELSC--TLEASTATLQAT 1996
Cdd:COG4913    500 AALRWVNRLHLRGrlvyERVRTGLPDPERPRLDPD--SLAGKldfkphpfrawlEAELGRRFDYVCvdSPEELRRHPRAI 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1997 LDTCQAR-----------------------ARQLEEALRVREGEIQTQALQHQEAMQHLQQElcqkeedLRQQDEQRQLL 2053
Cdd:COG4913    578 TRAGQVKgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAE-------LDALQERREAL 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2054 EKAVAQRSQENGIQEKQSLEQEKEEETRGLLES---LKELQLTVAQKEEEILMLREAQQRQNQEASSpshrsfpaekpsl 2130
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELERLDASsddLAALEEQLEELEAELEELEEELDELKGEIGR------------- 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958767515 2131 QLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQA 2208
Cdd:COG4913    718 LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 971-1175 3.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  971 QAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKAS 1050
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1051 LTLSLVE---------KEKRLLVLQEADSVRQreLVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEE 1121
Cdd:COG4942    102 QKEELAEllralyrlgRQPPLALLLSPEDFLD--AVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 1122 LEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLR 1175
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 823-1049 3.34e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  823 AEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKldKTLETLERERTELEMKLREQHTETEAL 902
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA--RRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  903 RAQREEERTQADSALYQMQLETEKERVslleTLLQTQKELADASQQLERLRQDMKVQKlKEQETTGMLQAQLRGAQQELK 982
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPL----ALLLSPEDFLDAVRRLQYLKYLAPARR-EQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515  983 EAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKA 1049
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1760-2009 3.37e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 3.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1760 ETSLLLTHREQETATlqQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqktSALQAAL 1839
Cdd:NF012221  1543 QADAVSKHAKQDDAA--QNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQR-----DAILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1840 EQAHVTLKERQGELEEHRGQVQRLQEelivEGRQVRA--LEEVLGDLRAESREHEKTVlalQQRCAEQAQEHEAEARTLQ 1917
Cdd:NF012221  1616 RAVTKELTTLAQGLDALDSQATYAGE----SGDQWRNpfAGGLLDRVQEQLDDAKKIS---GKQLADAKQRHVDNQQKVK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1918 DSWLQAQATLAEQEQELeaLRAENQYSRQQEEAAFGQAEALQEALSKAQAtlQEKEQRLLEQAELSCTLEASTATLQATL 1997
Cdd:NF012221  1689 DAVAKSEAGVAQGEQNQ--ANAEQDIDDAKADAEKRKDDALAKQNEAQQA--ESDANAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|..
gi 1958767515 1998 DTCQARARQLEE 2009
Cdd:NF012221  1765 AQADAKGAKQDE 1776
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1710-2115 3.56e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1710 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEAKEQGELR 1789
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1790 EQvLQGQLEEAQRALAQRDHEL-EALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELI 1868
Cdd:COG4717    159 RE-LEEELEELEAELAELQEELeELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1869 VEgRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQ----AQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYS 1944
Cdd:COG4717    238 AA-ALEERLKEARLLLLIAAALLALLGLGGSLLSLILtiagVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1945 RQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 2024
Cdd:COG4717    317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELL----REAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2025 HQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILML 2104
Cdd:COG4717    393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

                          410
                   ....*....|.
gi 1958767515 2105 REAQQRQNQEA 2115
Cdd:COG4717    473 ELLQELEELKA 483
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 632-863 4.93e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  632 SRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQL 711
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  712 QQLHQDAERQEEALARAGQEKEALV----RERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVT 787
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515  788 KSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKW 863
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
399-758 5.46e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 5.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  399 RQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQ 478
Cdd:PRK02224   249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  479 QLEVLEQEAWRLRRvnvelqlQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGE 558
Cdd:PRK02224   329 RLEECRVAAQAHNE-------EAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  559 LLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAE 638
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  639 QLRSALQVDLAEAERSREALwEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDA 718
Cdd:PRK02224   482 AELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1958767515  719 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAE 758
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA 600
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1585-1834 6.98e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 6.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1585 LTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLED 1664
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1665 QRtlqtKILEEDLEQIKHSLRERgqeLASQWQLMQERAED----GKSPSKAQRgSLEHLKLILRDKEKEVECQQERIQEL 1740
Cdd:COG4942     91 EI----AELRAELEAQKEELAEL---LRALYRLGRQPPLAlllsPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1741 QEHMGQLEQQLQGLHRKvgetslllthrEQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQ 1820
Cdd:COG4942    163 AALRAELEAERAELEAL-----------LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                          250
                   ....*....|....
gi 1958767515 1821 TRGQEESMKQKTSA 1834
Cdd:COG4942    232 LEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1686-1911 7.48e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1686 ERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 1765
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1766 THREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVT 1845
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1846 LKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEA 1911
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
705-954 8.15e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 8.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  705 EAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEvRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQnsvi 784
Cdd:COG4913    224 FEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  785 qvtksQLEVQIQTIIQAKEviqgevkclklELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWe 864
Cdd:COG4913    299 -----ELRAELARLEAELE-----------RLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR- 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  865 kerallqQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQmqletekervsLLETLLQTQKELAD 944
Cdd:COG4913    362 -------ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE-----------AEAALRDLRRELRE 423

                          250
                   ....*....|
gi 1958767515  945 ASQQLERLRQ 954
Cdd:COG4913    424 LEAEIASLER 433
PRK11281 PRK11281
mechanosensitive channel MscK;
1904-2295 1.00e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1904 EQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEaLQEALSKAQATLQEKEQRLLEQAELS 1983
Cdd:PRK11281    73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQ-LESRLAQTLDQLQNAQNDLAEYNSQL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1984 CTLEASTATLQATLDTCQARARQLEEALRvregeiqtQALQHQEAMQHLQQELCQKEEDL--RQQDEQRQLLEkavaqrs 2061
Cdd:PRK11281   152 VSLQTQPERAQAALYANSQRLQQIRNLLK--------GGKVGGKALRPSQRVLLQAEQALlnAQNDLQRKSLE------- 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2062 qenGIQEKQSLEQEKEEetrglleslkELQLTVAQKEEEILMLREAQQRQNQEASspshrsfpaEKPSLQLLLAQQDLER 2141
Cdd:PRK11281   217 ---GNTQLQDLLQKQRD----------YLTARIQRLEHQLQLLQEAINSKRLTLS---------EKTVQEAQSQDEAARI 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2142 LQNALRQTEAreiewrekAQGLALS--LAQSKASISSL--QEIAMflqASVLERESEQQR--------LQEELVLSRQAL 2209
Cdd:PRK11281   275 QANPLVAQEL--------EINLQLSqrLLKATEKLNTLtqQNLRV---KNWLDRLTQSERnikeqisvLKGSLLLSRILY 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2210 EEQQSRgphsssradqgPKAGQDTEPGEVIeAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQchNAQLRTTLEQVE 2289
Cdd:PRK11281   344 QQQQAL-----------PSADLIEGLADRI-ADLRLEQFEINQQRDALFQPDAYIDKLEAGHKSEV--TDEVRDALLQLL 409


                   ....*.
gi 1958767515 2290 RERRKL 2295
Cdd:PRK11281   410 DERREL 415
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
719-1177 1.01e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  719 ERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEgnlfEAQQQNSVIQVTKSQLEVQIQti 798
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELE----ELEAELEELREELEKLEKLLQ-- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  799 iqakeviqgevkclKLELDTERSHAEQERDAVARQLAQAEQEGQ--AALERQKVAHEEEVNRLQEKWEKERALLQQKLDK 876
Cdd:COG4717    127 --------------LLPLYQELEALEAELAELPERLEELEERLEelRELEEELEELEAELAELQEELEELLEQLSLATEE 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  877 TLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDM 956
Cdd:COG4717    193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLI 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  957 KVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIdlqkQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQE 1036
Cdd:COG4717    273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL----EEEELEELLAALGLPPDLSPEELLELLDRIEE 348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1037 CSRIQKELEKEKASLTLSLVEKEKRLLvLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAR-E 1115
Cdd:COG4717    349 LQELLREAEELEEELQLEELEQEIAAL-LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALdE 427

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767515 1116 AQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQpENQAQAQLRSL 1177
Cdd:COG4717    428 EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQE-LEELKAELREL 488
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1478-1867 1.14e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 47.51  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1478 RSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQrGQIQDLKKQLGTLECLALELEES 1557
Cdd:pfam10174  136 RKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAE-MQLGHLEVLLDQKEKENIHLREE 214

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1558 -HRKVEGQQ-----KVITELEGQRELQRVALTHLTLDLEERSQELQTQS-----------SQLHELENHSTRLAKELQER 1620
Cdd:pfam10174  215 lHRRNQLQPdpaktKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllhtedreeeiKQMEVYKSHSKFMKNKIDQL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1621 DQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVlEDQRTlqtKILEEDLEQIKHSLRERGQELASQWQLMQE 1700
Cdd:pfam10174  295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTA-KEQRA---AILQTEVDALRLRLEEKESFLNKKTKQLQD 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1701 RAEDgkspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQ 1780
Cdd:pfam10174  371 LTEE----KSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALS 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1781 EA-------KEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGEL 1853
Cdd:pfam10174  447 EKeriierlKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAV 526

                          410
                   ....*....|....
gi 1958767515 1854 EEHRGQVQRLQEEL 1867
Cdd:pfam10174  527 EQKKEECSKLENQL 540
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1578-2305 1.20e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1578 QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQ------ERDQEVMSQRQQIEELQKQKEQLTQDLERKGQE 1651
Cdd:COG3096    290 LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQaasdhlNLVQTALRQQEKIERYQEDLEELTERLEEQEEV 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1652 LVLQKERIQVLEDQRTLQtkilEEDLEQIKHSLRERGQEL------ASQWQLMQERAEDGKSPSKAQRGSLEHLK---LI 1722
Cdd:COG3096    370 VEEAAEQLAEAEARLEAA----EEEVDSLKSQLADYQQALdvqqtrAIQYQQAVQALEKARALCGLPDLTPENAEdylAA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1723 LRDKEKEVECQ----QERIQELQEHMGQLEQQLQGLHRKVGETSlllthREQETATLQQRLQEAKEQGEL--REQVLQGQ 1796
Cdd:COG3096    446 FRAKEQQATEEvlelEQKLSVADAARRQFEKAYELVCKIAGEVE-----RSQAWQTARELLRRYRSQQALaqRLQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1797 LEEAQRALAQRdHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRA 1876
Cdd:COG3096    521 LAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAA 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1877 LEEVLgdlraesrehektvLALQQRcAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAafgQAE 1956
Cdd:COG3096    600 RAPAW--------------LAAQDA-LERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES---QIE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1957 ALQEALSKAQATLQEKEQR----LLEQAELSCTLE-----------ASTATLQATLDTCQARARQLE---EALRVREGEI 2018
Cdd:COG3096    662 RLSQPGGAEDPRLLALAERlggvLLSEIYDDVTLEdapyfsalygpARHAIVVPDLSAVKEQLAGLEdcpEDLYLIEGDP 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2019 QTQALQHQEAmQHLQQELCQKEEDL--------------RQQDEQRqlLEKAVAQRSQENGIQEKQSLEQEKEEETRGLL 2084
Cdd:COG3096    742 DSFDDSVFDA-EELEDAVVVKLSDRqwrysrfpevplfgRAAREKR--LEELRAERDELAEQYAKASFDVQKLQRLHQAF 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2085 ESLKELQLTVAQKEEEILMLREAQQRQNQeasspshrsfpaekpslqlllaqqdlerLQNALRQTEAREIEWREKAqgla 2164
Cdd:COG3096    819 SQFVGGHLAVAFAPDPEAELAALRQRRSE----------------------------LERELAQHRAQEQQLRQQL---- 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2165 lslAQSKASISSLQeiAMFLQASVLERESEQQR---LQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEA 2241
Cdd:COG3096    867 ---DQLKEQLQLLN--KLLPQANLLADETLADRleeLREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQA 941

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767515 2242 EPSPGVGEKEQLRQRLERLQQAVAELE----VDRSKLQCHNA----QLRTTLEQVERERRKLkRDSLRASRA 2305
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFALSEVVQRRPhfsyEDAVGLLGENSdlneKLRARLEQAEEARREA-REQLRQAQA 1012
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 879-1510 1.36e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  879 ETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLEtllQTQKELADASQQLERLRQDMKV 958
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAE---EMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  959 QKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQK---DKIDLQKQVEDLTSQLVTHNDSQ-------RLVKQEIE 1028
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLLEDQNsklskerKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1029 EKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKE 1108
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1109 ADFVAREAQLLEELEASRIAERQVRaslwaqEAKAAQLQLQlrsteaqlEALVAEQQPENQAQAQLRSLYSVLQQAlgsa 1188
Cdd:pfam01576  243 EELQAALARLEEETAQKNNALKKIR------ELEAQISELQ--------EDLESERAARNKAEKQRRDLGEELEAL---- 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1189 cerRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQdlwkaqQARDDLRDQVQKLVQRLTDT 1268
Cdd:pfam01576  305 ---KTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHT------QALEELTEQLEQAKRNKANL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1269 EAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLhetmaslQSRLRQAELQKMEAQNDRELLQASKEKLSAQ 1348
Cdd:pfam01576  376 EKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-------QARLSESERQRAELAEKLSKLQSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1349 VEHLQacvtearaqaSAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNRERE 1428
Cdd:pfam01576  449 LNEAE----------GKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQ 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1429 VETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELEND 1508
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSN 598


                   ..
gi 1958767515 1509 RE 1510
Cdd:pfam01576  599 LE 600
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1282-1903 1.70e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1282 LQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQkmeAQNDRELLQASKEKLSAQVEHL-QACVTEAR 1360
Cdd:pfam05483  160 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQ---AENARLEMHFKLKEDHEKIQHLeEEYKKEIN 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1361 AQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKvaqgkalQENLTLLAQTLSNREREVETLQAEVQELE 1440
Cdd:pfam05483  237 DKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQ-------DENLKELIEKKDHLTKELEDIKMSLQRSM 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1441 KQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRS-VLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQ 1519
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSfVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKK 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1520 LLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVE--------------GQQKVITELEGQRELQRVALTHL 1585
Cdd:pfam05483  390 SSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEelkgkeqelifllqAREKEIHDLEIQLTAIKTSEEHY 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1586 TLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVmsqRQQIEELQKQKEQLTQDlERKGQELVLQKERIQVLEDQ 1665
Cdd:pfam05483  470 LKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEA---SDMTLELKKHQEDIINC-KKQEERMLKQIENLEEKEMN 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1666 rtlqtkiLEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMG 1745
Cdd:pfam05483  546 -------LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENK 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1746 QLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEA----KEQGELREQVLQGQLEEAQRALAQRDhelEALRQEQQQT 1821
Cdd:pfam05483  619 ALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIAD---EAVKLQKEID 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1822 RGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQR---LQEELIVEGRQVRA-LEEVLGDLRAESREHEKTVLA 1897
Cdd:pfam05483  696 KRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEqssAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKME 775


                   ....*.
gi 1958767515 1898 LQQRCA 1903
Cdd:pfam05483  776 AKENTA 781
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1771-2100 1.78e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1771 ETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLK-ER 1849
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmER 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1850 QGELEEHRgqvqrlQEELIVEGRQVRalEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeARTLQDSWLQAQATLAE 1929
Cdd:pfam17380  347 ERELERIR------QEERKRELERIR--QEEIAMEISRMRELERLQMERQQKNERVRQELEA-ARKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1930 QEQELEALRAEnqysrqQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAElsctleastatlqatldtcqaRARQLEE 2009
Cdd:pfam17380  418 QKVEMEQIRAE------QEEARQREVRRLEEERAREMERVRLEEQERQQQVE---------------------RLRQQEE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2010 ALRVREGEIQTQALQHQEAMQH----LQQELCQKEEDLRQQDEQRQLLEKAVAQRsQENGIQEKQSLEQEKEEETRGLLE 2085
Cdd:pfam17380  471 ERKRKKLELEKEKRDRKRAEEQrrkiLEKELEERKQAMIEEERKRKLLEKEMEER-QKAIYEEERRREAEEERRKQQEME 549

                          330
                   ....*....|....*
gi 1958767515 2086 SLKELQLTVAQKEEE 2100
Cdd:pfam17380  550 ERRRIQEQMRKATEE 564
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1488-2212 2.04e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1488 VQEREQKLSVQRDQIRELEndREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKV 1567
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLA--RQFALCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEH 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1568 -ITELEGQRELQRVAltHLTLDLEERSQELQTQSSQLH----ELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQ-- 1640
Cdd:pfam12128  226 wIRDIQAIAGIMKIR--PEFTKLQQEFNTLESAELRLShlhfGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEkr 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1641 --LTQDLERKGQELVLQKERIQVLEDQRTlqtKILEEDLEQIKHSLrERGQELASQWQLMQERAE---------DGKSPS 1709
Cdd:pfam12128  304 deLNGELSAADAAVAKDRSELEALEDQHG---AFLDADIETAAADQ-EQLPSWQSELENLEERLKaltgkhqdvTAKYNR 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1710 KAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLhrkvgetslllthREQETATLQqRLQEAKEQGELR 1789
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL-------------REQLEAGKL-EFNEEEYRLKSR 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1790 EQVLQGQLEEAQRA------LAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRL 1863
Cdd:pfam12128  446 LGELKLRLNQATATpelllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDEL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1864 QEELIVegrQVRALEEVLGDLRAESREHEKTVLALQQRCAEQaqeheaeartlqdswLQAQATLAEQEQELEALRAENQY 1943
Cdd:pfam12128  526 ELQLFP---QAGTLLHFLRKEAPDWEQSIGKVISPELLHRTD---------------LDPEVWDGSVGGELNLYGVKLDL 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1944 SRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL 2023
Cdd:pfam12128  588 KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2024 QHQEAMQHLQQelcQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEEETRGLLESLKELQLtvAQKEEEILM 2103
Cdd:pfam12128  668 KKNKALAERKD---SANERLNSLEAQLKQLDKKHQAWLEE--QKEQKREARTEKQAYWQVVEGALDAQL--ALLKAAIAA 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2104 LREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDL-ERLQNALRQTEAREIEWREKAQGLALSLAQSKasiSSLQEIAM 2182
Cdd:pfam12128  741 RRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREiRTLERKIERIAVRRQEVLRYFDWYQETWLQRR---PRLATQLS 817

                          730       740       750
                   ....*....|....*....|....*....|
gi 1958767515 2183 FLQASVLERESEQQRLQEELVLSRQALEEQ 2212
Cdd:pfam12128  818 NIERAISELQQQLARLIADTKLRRAKLEME 847
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1237-1544 2.35e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1237 LQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 1316
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1317 LQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNE----EIESERE 1392
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlsrSINKIKQ 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1393 RAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQEL-----EKQREMQKAALELLSLD--LKKRS--RE 1463
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekkEKESKISDLEDELNKDDfeLKKENleKE 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1464 VDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQ 1543
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   .
gi 1958767515 1544 L 1544
Cdd:TIGR04523  643 L 643
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-492 3.08e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  245 LLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELME 324
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  325 HEASLSRnAQEEKLSLQHVIKDITQALASVEEEDTVTQTpgsenslqsdyndLSQFDSQDPNKALTLVHSVLTRRQQAVQ 404
Cdd:COG4942     88 LEKEIAE-LRAELEAQKEELAELLRALYRLGRQPPLALL-------------LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  405 DLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLE 484
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233


                   ....*...
gi 1958767515  485 QEAWRLRR 492
Cdd:COG4942    234 AEAAAAAE 241
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
375-888 3.12e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  375 NDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLtgerDALAGQTVD 454
Cdd:PRK02224   187 GSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL----ETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  455 LQGEVDSLSKERELLQTARGELQQQLEVLEQEAwRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEA 534
Cdd:PRK02224   263 LRETIAETEREREELAEEVRDLRERLEELEEER-DDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  535 KQSESLSELIA-LREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDK 613
Cdd:PRK02224   342 EEAESLREDADdLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  614 VALNQQLLQLEQENQSMCSRVEAAEQLRSA----------------------------LQVDLAEAERSREAL------W 659
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetieedrerveeLEAELEDLEEEVEEVeerlerA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  660 EEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRER 739
Cdd:PRK02224   502 EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  740 AALEVRLQAVER------DRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQI--------QTIIQAKEVI 805
Cdd:PRK02224   582 AELKERIESLERirtllaAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdearieeaREDKERAEEY 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  806 QGEVKCLKLELDTERSHAEQERDAVARQLAQAE--QEGQAALERQKVAHE---EEVNRLQEKWEKERALLQQKLDKTLET 880
Cdd:PRK02224   662 LEQVEEKLDELREERDDLQAEIGAVENELEELEelRERREALENRVEALEalyDEAEELESMYGDLRAELRQRNVETLER 741


                   ....*...
gi 1958767515  881 LERERTEL 888
Cdd:PRK02224   742 MLNETFDL 749
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
1737-2187 4.28e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 45.67  E-value: 4.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1737 IQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQ 1816
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1817 EQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVL 1896
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1897 ALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRL 1976
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAA 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1977 LEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKA 2056
Cdd:COG5278    318 AAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAA 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2057 VAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQ 2136
Cdd:COG5278    398 AAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAAL 477

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 2137 QDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQAS 2187
Cdd:COG5278    478 AAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASA 528
PRK11281 PRK11281
mechanosensitive channel MscK;
1219-1448 4.47e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.67  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1219 LKRGPLLTALSAEAValalqklhQDLWKAQ---QARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQL-SQSQEEKS 1294
Cdd:PRK11281    48 LNKQKLLEAEDKLVQ--------QDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNdEETRETLS 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1295 KWEGKQnsLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASkekLSAQVEHLQACVTEARAQASAAGVLEEDLR 1374
Cdd:PRK11281   120 TLSLRQ--LESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAA---LYANSQRLQQIRNLLKGGKVGGKALRPSQR 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1375 TARSA-LKLKNEEIESERERAQA-------LQEQGELKVAQGKALQENLTLLaQTLSNREREVETlQAEVQELEKQREMQ 1446
Cdd:PRK11281   195 VLLQAeQALLNAQNDLQRKSLEGntqlqdlLQKQRDYLTARIQRLEHQLQLL-QEAINSKRLTLS-EKTVQEAQSQDEAA 272


                   ..
gi 1958767515 1447 KA 1448
Cdd:PRK11281   273 RI 274
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
983-1196 4.91e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  983 EAIQQHRDDLAAFQKDKIDLQKQVEDLTsQLVTHNdsqrlvkQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRL 1062
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLE-PIRELA-------ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1063 LvlqeadsvrQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADfvaREAQLLEELEASRIAERQVRASLWAQEAK 1142
Cdd:COG4913    300 L---------RAELARLEAELERLEARLDALREELDELEAQIRGNGGD---RLEQLEREIERLERELEERERRRARLEAL 367

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 1143 AAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQALGSACERRPELR 1196
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLR 418
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1747-2116 5.27e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.27  E-value: 5.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1747 LEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1826
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1827 SMKQKTSALQAALEQAHVTLKE--------------RQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHE 1892
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIREleediktltqrvleRETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1893 KTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATL 1969
Cdd:pfam07888  192 KEFQELRNSLAQrdtQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1970 QEKEQRLLEQAELSCTLEastatlQATLDTCQARARQLEEalrvREGEIQTQALQHqEAMQHLQQELCQKEEDLRQQDEQ 2049
Cdd:pfam07888  272 AELHQARLQAAQLTLQLA------DASLALREGRARWAQE----RETLQQSAEADK-DRIEKLSAELQRLEERLQEERME 340

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 2050 RQLLEKAVAQRSQENGIQEKQSlEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEAS 2116
Cdd:pfam07888  341 REKLEVELGREKDCNRVQLSES-RRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 846-1134 5.77e-04

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 44.52  E-value: 5.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  846 ERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREE----ERTQADSALYQMQ 921
Cdd:pfam13868   32 KRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEeklqEREQMDEIVERIQ 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  922 LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKE-------QETTGMLQAQLRGAQQELKEAIQQHRDDLAA 994
Cdd:pfam13868  112 EEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEderileyLKEKAEREEEREAEREEIEEEKEREIARLRA 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  995 FQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLlvLQEADSVRQR 1074
Cdd:pfam13868  192 QQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAERE--EEEFERMLRK 269

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1075 ELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRA 1134
Cdd:pfam13868  270 QAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRE 329
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1487-1716 6.15e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 6.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1487 AVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQK 1566
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1567 VITELEGQRELQRVALThltldlEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLE 1646
Cdd:COG4942    111 RALYRLGRQPPLALLLS------PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515 1647 RKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPS-KAQRGSL 1716
Cdd:COG4942    185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGfAALKGKL 255
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1919-2153 6.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 6.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1919 SWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEqaelsctLEASTATLQATLD 1998
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA-------LEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1999 TCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQEngIQEKQSLEQEKEE 2078
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQ--AEELRADLAELAA 164

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958767515 2079 ETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEARE 2153
Cdd:COG4942    165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
537-1129 6.23e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 6.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  537 SESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVal 616
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  617 nqqllqleqenqsmcsRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETG--AELQAELRGAREEKEELK 694
Cdd:PRK03918   246 ----------------ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekAEEYIKLSEFYEEYLDEL 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  695 EKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEqvlgLRSAKEQLEGNl 774
Cdd:PRK03918   310 REIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE----LERLKKRLTGL- 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  775 feaqqqnsviqvTKSQLEVQIQTIIQAKEVIQGEVKCLKLELdtershaeqerdavaRQLAQAEQEGQAALERQKVAHEE 854
Cdd:PRK03918   385 ------------TPEKLEKELEELEKAKEEIEEEISKITARI---------------GELKKEIKELKKAIEELKKAKGK 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  855 EVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREqhteteaLRAQREEertqadsalyqmqLETEKERVSLLET 934
Cdd:PRK03918   438 CPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK-------LRKELRE-------------LEKVLKKESELIK 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  935 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEAIQQhrddLAAFQKDKIDLQKQVEDLTSQLV 1014
Cdd:PRK03918   498 LKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK----LEELKKKLAELEKKLDELEEELA 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1015 T-HNDSQRLVKQEIEEKVREAQECSRIQKELekekasltLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQREL 1093
Cdd:PRK03918   574 ElLKELEELGFESVEELEERLKELEPFYNEY--------LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEEL 645

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1958767515 1094 GVQVELLRQEVKEKEADFVAREAQLLEELEASRIAE 1129
Cdd:PRK03918   646 RKELEELEKKYSEEEYEELREEYLELSRELAGLRAE 681
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1242-1537 6.49e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 6.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1242 QDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRL 1321
Cdd:COG4372     31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1322 RQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ-ALQEQ 1400
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAlDELLK 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1401 GELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSV 1480
Cdd:COG4372    191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVE 270

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1481 LEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQI 1537
Cdd:COG4372    271 KDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
814-987 6.72e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 6.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  814 LELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLR 893
Cdd:COG3206    208 VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYT 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  894 EQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQK--LKEQETTGMLQ 971
Cdd:COG3206    288 PNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRrlEREVEVARELY 367

                          170
                   ....*....|....*.
gi 1958767515  972 AQLRGAQQELKEAIQQ 987
Cdd:COG3206    368 ESLLQRLEEARLAEAL 383
46 PHA02562
endonuclease subunit; Provisional
 1591-1831 7.34e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 7.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1591 ERSQELQTQSSQLHELEnhstrlakelqerdQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQT 1670
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQ--------------QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDEL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1671 KILEEDLEQIKHSLRERGQELA---SQWQLMQERA----EDGKSPSKAQrgslehlklilrdkekEVECQQERIQELQEH 1743
Cdd:PHA02562   244 LNLVMDIEDPSAALNKLNTAAAkikSKIEQFQKVIkmyeKGGVCPTCTQ----------------QISEGPDRITKIKDK 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1744 MGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQEAKEQGELREQVLQG----------QLEEAQRALAQRDHELEA 1813
Cdd:PHA02562   308 LKELQHSLEKLDTAIDE----LEEIMDEFNEQSKKLLELKNKISTNKQSLITlvdkakkvkaAIEELQAEFVDNAEELAK 383

                          250
                   ....*....|....*...
gi 1958767515 1814 LRQEQQQTRGQEESMKQK 1831
Cdd:PHA02562   384 LQDELDKIVKTKSELVKE 401
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1422-1976 8.25e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 8.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1422 LSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQ 1501
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1502 IRELENDREAQRTALEHQLLDLEQKAQVIESQrgqiqdLKKQLGTLECLALELEESHRKVEGQQKVITELEGQREL---- 1577
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKN------IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLleke 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1578 -------------QRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQD 1644
Cdd:TIGR04523  182 klniqknidkiknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1645 LERKGQELvlqKERIQVLEDQRTLqTKILEEDLEQIKHSLRERGQELASQWqlmqeraedgkspskaqrgsLEHLKLILR 1724
Cdd:TIGR04523  262 QNKIKKQL---SEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDW--------------------NKELKSELK 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1725 DKEKEVECQQERIQELQEHMGQLEQQLQGLHRKvgetsllLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRaL 1804
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKE-------LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKN-L 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1805 AQRDHELEalrqeqQQTRGQEESMKQKTSalqaaleqahvTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDL 1884
Cdd:TIGR04523  390 ESQINDLE------SKIQNQEKLNQQKDE-----------QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1885 RAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSK 1964
Cdd:TIGR04523  453 ELIIKNLDNTRESLET----QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          570
                   ....*....|..
gi 1958767515 1965 AQATLQEKEQRL 1976
Cdd:TIGR04523  529 LESEKKEKESKI 540
46 PHA02562
endonuclease subunit; Provisional
 845-1060 9.32e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 9.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  845 LERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEmKLREQHTETEalraQREEERTQADSALYQ--MQL 922
Cdd:PHA02562   193 IQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE-ELTDELLNLV----MDIEDPSAALNKLNTaaAKI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  923 ETEKERVSLLETLLQTQKELADASQQLERlrQDMKVQKLKEQETTGMLQ-AQLRGAQQELKEAIqqhrDDLAAFQKDKID 1001
Cdd:PHA02562   268 KSKIEQFQKVIKMYEKGGVCPTCTQQISE--GPDRITKIKDKLKELQHSlEKLDTAIDELEEIM----DEFNEQSKKLLE 341

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767515 1002 LQKQVEDLTSQLVTHNDSQRLVKQEIE----EKVREAQECSRIQKELEKEKAslTLSLVEKEK 1060
Cdd:PHA02562   342 LKNKISTNKQSLITLVDKAKKVKAAIEelqaEFVDNAEELAKLQDELDKIVK--TKSELVKEK 402
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-658 1.00e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515   46 EAQKRQATLVRKLQA--KVLQYRSWCQDLEKRLEatgglipqRWESVEEpNLEQLLIRLEEEQQRCESLVEVNTELRLHM 123
Cdd:COG1196    206 ERQAEKAERYRELKEelKELEAELLLLKLRELEA--------ELEELEA-ELEELEAELEELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  124 EKADVVNKALQEDVEKLTVDWSRARDELMRKESQwrmeqeffkgylrgehgrllsvwrevvtfRRHFLKMKSATDRDLTE 203
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEER-----------------------------RRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  204 LKAEHARLSGSLLTCCLRLTLRAQSRDSSGSGRSDESEpaQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDR 283
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  284 VTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALASVEEEDTVTQT 363
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  364 PGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEA------MSFLQQQHNQWEEEGKALRER 437
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAaleaalAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  438 LQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGekleqqeELHL 517
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA-------ALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  518 AVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRA 597
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958767515  598 AAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREAL 658
Cdd:COG1196    719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1638-1940 1.01e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1638 KEQLTQDLER-KGQELVLQKERIQVLE------------DQRTLQTKILEEDLEQIKHSLRErgqelasqwQLMQERAED 1704
Cdd:PRK10929    25 EKQITQELEQaKAAKTPAQAEIVEALQsalnwleerkgsLERAKQYQQVIDNFPKLSAELRQ---------QLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1705 GKSPSKAQRGSLEHLKLI----LRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGEtsllLTHREQETATLQQRLQ 1780
Cdd:PRK10929    96 RSVPPNMSTDALEQEILQvssqLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNE----IERRLQTLGTPNTPLA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1781 EAkeqgelreQVLQGQLEEAQRALAQRDHELEAL----RQEqqQTRGQEESMKQKTSALQAALEQAHVTLK-ERQGELEE 1855
Cdd:PRK10929   172 QA--------QLTALQAESAALKALVDELELAQLsannRQE--LARLRSELAKKRSQQLDAYLQALRNQLNsQRQREAER 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1856 HRGQVQRLQE------ELIVEgrQVRALEEVLGDLRAESREHEktVLALQQRcaeqaqehEAEARTLQDSwlQAQATLAE 1929
Cdd:PRK10929   242 ALESTELLAEqsgdlpKSIVA--QFKINRELSQALNQQAQRMD--LIASQQR--------QAASQTLQVR--QALNTLRE 307

                          330
                   ....*....|....*...
gi 1958767515 1930 QEQEL-------EALRAE 1940
Cdd:PRK10929   308 QSQWLgvsnalgEALRAQ 325
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1775-2019 1.10e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1775 LQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQ--QTRGQEESMKQKTSALQAALEQAhvtlkerQGE 1852
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEA-------RAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1853 LEEHRGQVQRLQEELIVEGRQVRALEE--VLGDLRAEsrehektVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQ 1930
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQ-------LAELEAELAELSARYTPNHPDVI----ALRAQIAAL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1931 EQELEALRAENQYSRQQE-EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLdtcqARARQLEE 2009
Cdd:COG3206    304 RAQLQQEAQRILASLEAElEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL----QRLEEARL 379

                          250
                   ....*....|
gi 1958767515 2010 ALRVREGEIQ 2019
Cdd:COG3206    380 AEALTVGNVR 389
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1854-2062 1.11e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1854 EEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTL----QDSWLQAQATLAE 1929
Cdd:COG3914      1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAageaAAAAAALLLLAAL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1930 QEQELEALRAENQYsrQQEEAAFGQAEALQEALSKAQATL--QEKEQRLLEQAELSCT----LEASTATLQATLDTCQAR 2003
Cdd:COG3914     81 LELAALLLQALGRY--EEALALYRRALALNPDNAEALFNLgnLLLALGRLEEALAALRralaLNPDFAEAYLNLGEALRR 158

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958767515 2004 ARQLEEALrvregEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQ 2062
Cdd:COG3914    159 LGRLEEAI-----AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 240-596 1.29e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  240 SEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNH 319
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  320 AELMEHEASLSRNAqEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQdpnkaLTLVHSVLTRR 399
Cdd:TIGR02169  751 QEIENVKSELKELE-ARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR-----LREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  400 QQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQ 479
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  480 LEVLEQEAWRLRrvnvELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSEsLSELIALREALESSRLAGEl 559
Cdd:TIGR02169  905 IEELEAQIEKKR----KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAE-LQRVEEEIRALEPVNMLAI- 978

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1958767515  560 lkQEQEEVAAALAraeqsivELSSSENSLKAEVADLR 596
Cdd:TIGR02169  979 --QEYEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
970-1188 2.07e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  970 LQAQLRGAQQELKEA---IQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEK 1046
Cdd:COG4372     43 LQEELEQLREELEQAreeLEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1047 EKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASR 1126
Cdd:COG4372    123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEEL 202

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958767515 1127 IAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSA 1188
Cdd:COG4372    203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1379-2127 2.26e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1379 ALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVET---LQAEVQELEKQREMQKAAlELLSL 1455
Cdd:TIGR00606  170 ALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIrdqITSKEAQLESSREIVKSY-ENELD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1456 DLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQR--------DQIRELENDREAQRTALEHQLLDLEQKA 1527
Cdd:TIGR00606  249 PLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdEQLNDLYHNHQRTVREKERELVDCQREL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1528 QVIESQRGQIQDLKKQLgtleclalelEESHRKVEGQQKVITELEGQRELQRVAL-THLTLDLEERSQELQTQSSQLHEL 1606
Cdd:TIGR00606  329 EKLNKERRLLNQEKTEL----------LVEQGRLQLQADRHQEHIRARDSLIQSLaTRLELDGFERGPFSERQIKNFHTL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1607 -----ENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLErkgqelvlqkeriqvledqrtLQTKILEEDLEQIK 1681
Cdd:TIGR00606  399 vierqEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE---------------------LKKEILEKKQEELK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1682 HSLRERGQELASQWQLMQERAEDGKspSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGET 1761
Cdd:TIGR00606  458 FVIKELQQLEGSSDRILELDQELRK--AERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1762 SLLLTHREQETATLQQRLQEAKEQGELREQV---------------LQGQLEEAQRALAQRDHELEALRQEQQQTRGQEE 1826
Cdd:TIGR00606  536 QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpnkkqledwlhsKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1827 SMKQKTSALQAAL------EQAHVTLKERQGELEEHRGQVQRLQ----------EELIVEGRQVRALEEVLGDLRAESRE 1890
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRAMLAgatavysqfiTQLTDENQSCCPVCQRVFQTEAELQE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1891 HEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKaQATLQ 1970
Cdd:TIGR00606  696 FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE-QETLL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1971 EKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQAL-QHQEAMQHLQQELCQKEEDLRQQDEQ 2049
Cdd:TIGR00606  775 GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVnQEKQEKQHELDTVVSKIELNRKLIQD 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2050 RQLLEKAVAQRSQENG-----IQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFP 2124
Cdd:TIGR00606  855 QQEQIQHLKSKTNELKseklqIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKET 934


                   ...
gi 1958767515 2125 AEK 2127
Cdd:TIGR00606  935 SNK 937
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 652-1543 2.77e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.04  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  652 ERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEelkeklneahhqqeaataqlqqlhqdaerqeeALARAGQE 731
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKK--------------------------------ALEYYQLK 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  732 KEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQqnsviqvtksQLEVQIQTIIQAKEVIQGEVKC 811
Cdd:pfam02463  217 EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE----------EKLAQVLKENKEEEKEKKLQEE 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  812 LKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMK 891
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  892 LREQHTETEALRAQREEERTQADSALYQMQLEtekervsLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQ 971
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELE-------LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  972 AQLRGAQQELKEAIQqhrDDLAAFQKDKIDLQKQVEDLTSqlvTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASL 1051
Cdd:pfam02463  440 ELKQGKLTEEKEELE---KQELKLLKDELELKKSEDLLKE---TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLL 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1052 TLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQ 1131
Cdd:pfam02463  514 ALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1132 VRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPD 1211
Cdd:pfam02463  594 IAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1212 QNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQvhsELQDLQRQLSQSQE 1291
Cdd:pfam02463  674 ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE---ELKLLKQKIDEEEE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1292 EKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLqacvtearaqaSAAGVLEE 1371
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK-----------EEAELLEE 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1372 DLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALE 1451
Cdd:pfam02463  820 EQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEK 899

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1452 LLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREqkLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIE 1531
Cdd:pfam02463  900 KELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL--LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNL 977

                          890
                   ....*....|..
gi 1958767515 1532 SQRGQIQDLKKQ 1543
Cdd:pfam02463  978 MAIEEFEEKEER 989
mukB PRK04863
chromosome partition protein MukB;
1725-1981 2.87e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1725 DKEKEVECQQERIQELQEHMGQLE--------------QQLQGLHRKVGETSLLlthreqETATLQQRLQEAKEQGELRE 1790
Cdd:PRK04863   834 DPEAELRQLNRRRVELERALADHEsqeqqqrsqleqakEGLSALNRLLPRLNLL------ADETLADRVEEIREQLDEAE 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1791 QVLQ---------GQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALE-QAHVTLKERQGELEEHRGQV 1860
Cdd:PRK04863   908 EAKRfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQrRAHFSYEDAAEMLAKNSDLN 987

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1861 QRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQ----EQELEA 1936
Cdd:PRK04863   988 EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERararRDELHA 1067

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1958767515 1937 LRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAE 1981
Cdd:PRK04863  1068 RLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1875-1977 3.21e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 3.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1875 RALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQdswlQAQATLAEQEQELEALRAENQYSRQQEEAAFgq 1954
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAA----ELEEKQQELEAQLEQLQEKAAETSQERKQKR-- 218

                           90       100
                   ....*....|....*....|...
gi 1958767515 1955 AEALQEALSKAQatLQEKEQRLL 1977
Cdd:PRK11448   219 KEITDQAAKRLE--LSEEETRIL 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1306-1817 3.45e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1306 ELRDLHETMASLQSRLRQaeLQKMEAQNDREllqaskEKLSAQVEHLQACVTEARAQASAagvleedlrtaRSALKLKNE 1385
Cdd:COG4913    236 DLERAHEALEDAREQIEL--LEPIRELAERY------AAARERLAELEYLRAALRLWFAQ-----------RRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1386 EIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVD 1465
Cdd:COG4913    297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLP 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1466 LQQEQIQELeqcRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQD-LKKQL 1544
Cdd:COG4913    377 ASAEEFAAL---RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDaLAEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1545 GTLECL----------ALELEESHRKVEG---------------QQKVI-----TELEGQRELQRVALTH---LTLDLEE 1591
Cdd:COG4913    454 GLDEAElpfvgelievRPEEERWRGAIERvlggfaltllvppehYAAALrwvnrLHLRGRLVYERVRTGLpdpERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1592 RS--QELQTQSSQLH--------------------ELENHSTRLAKELQERDQEVMSQ-----------------RQQIE 1632
Cdd:COG4913    534 DSlaGKLDFKPHPFRawleaelgrrfdyvcvdspeELRRHPRAITRAGQVKGNGTRHEkddrrrirsryvlgfdnRAKLA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1633 ELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERgqELAsQWQLMQERAEDGKSPSKAQ 1712
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA-ELEAELERLDASSDDLAAL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1713 RGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLthREQETATLQQRLQEAKEQGELRE-- 1790
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA--RLELRALLEERFAAALGDAVERElr 768

                          570       580
                   ....*....|....*....|....*..
gi 1958767515 1791 QVLQGQLEEAQRALAQRDHELEALRQE 1817
Cdd:COG4913    769 ENLEERIDALRARLNRAEEELERAMRA 795
MutS2 COG1193
dsDNA-specific endonuclease/ATPase MutS2 [Replication, recombination and repair];
843-983 3.70e-03

dsDNA-specific endonuclease/ATPase MutS2 [Replication, recombination and repair];


Pssm-ID: 440806 [Multi-domain]  Cd Length: 784  Bit Score: 42.82  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  843 AALERQKVAHEEEvnrlqekwekerallqqkldktLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQL 922
Cdd:COG1193    521 EELERERRELEEE----------------------REEAERLREELEKLREELEEKLEELEEEKEEILEKAREEAEEILR 578

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958767515  923 ETEKErvslLETLLQTQKELADASQQLERLRQDMK--VQKLKEQETTGMLQAQLRGAQQELKE 983
Cdd:COG1193    579 EARKE----AEELIRELREAQAEEEELKEARKKLEelKQELEEKLEKPKKKAKPAKPPEELKV 637
46 PHA02562
endonuclease subunit; Provisional
 1254-1459 3.90e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 3.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1254 LRDQVQKLVQRLTDTEAQKSQVHSELqDLQRQLSQSQEEKSK-----WEGKQNSLESELRDLHETMASLQSRLRQAELQK 1328
Cdd:PHA02562   172 NKDKIRELNQQIQTLDMKIDHIQQQI-KTYNKNIEEQRKKNGeniarKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1329 MEAQNDRELLQASKEKLSAQVEHLQ-------------ACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQ 1395
Cdd:PHA02562   251 EDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcpTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD 330

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515 1396 ALQEQgelkVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKK 1459
Cdd:PHA02562   331 EFNEQ----SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1237-1452 4.06e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1237 LQKLHQDLWKAQQARDDLRDQvqklvQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMAS 1316
Cdd:COG3206    184 LPELRKELEEAEAALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1317 LQSRLRQAELQKMEAQNDRELLQASKeklSAQVEHLQacVTEARAQASAagvLEEDLRTARSALKlknEEIESERERAQA 1396
Cdd:COG3206    259 LLQSPVIQQLRAQLAELEAELAELSA---RYTPNHPD--VIALRAQIAA---LRAQLQQEAQRIL---ASLEAELEALQA 327

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1397 LQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALEL 1452
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEAL 383
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1791-2022 4.35e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1791 QVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVE 1870
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1871 GRQVRALEEVLG-----------DLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRA 1939
Cdd:COG3883     99 GGSVSYLDVLLGsesfsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1940 ENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQ 2019
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ...
gi 1958767515 2020 TQA 2022
Cdd:COG3883    259 AGS 261
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1064-1285 4.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1064 VLQEADSVRQ--RELVSLRQDIQEAQEgqrelgvQVELLRQ--EVKEKEADFVAREAQLLEELEASRIAERQVRASLWaq 1139
Cdd:COG4913    223 TFEAADALVEhfDDLERAHEALEDARE-------QIELLEPirELAERYAAARERLAELEYLRAALRLWFAQRRLELL-- 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1140 EAKAAQLQLQLRSTEAQLEALVAEQQpenQAQAQLRSLYSVLQQALGSACER-RPELRGGGDSVPTpwgSDPDQNGASRL 1218
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLD---ALREELDELEAQIRGNGGDRLEQlEREIERLERELEE---RERRRARLEAL 367

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1219 LKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQ 1285
Cdd:COG4913    368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
PRK12704 PRK12704
phosphodiesterase; Provisional
 1018-1173 4.63e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1018 DSQRLVKQEIEEKVREAQ-ECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEgqrelgvQ 1096
Cdd:PRK12704    46 EAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEK-------E 118

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1097 VELLRQEVKEKEADFVAREAQLLEELEasRIaerqvrASLWAQEAKAAQLQlQLRStEAQLEALVAEQQPENQAQAQ 1173
Cdd:PRK12704   119 LEQKQQELEKKEEELEELIEEQLQELE--RI------SGLTAEEAKEILLE-KVEE-EARHEAAVLIKEIEEEAKEE 185
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1588-1691 5.07e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 5.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1588 DLEERSQELQTQSSQLHELENHSTRLAKELQErdqevmsqrqQIEELQKQKEQLTQDLERKGQELV--LQKERIQVLEDQ 1665
Cdd:PRK00409   524 SLEELERELEQKAEEAEALLKEAEKLKEELEE----------KKEKLQEEEDKLLEEAEKEAQQAIkeAKKEADEIIKEL 593

                           90       100       110
                   ....*....|....*....|....*....|
gi 1958767515 1666 RTLQ----TKILEEDLEQIKHSLRERGQEL 1691
Cdd:PRK00409   594 RQLQkggyASVKAHELIEARKRLNKANEKK 623
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1862-2008 5.11e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 5.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1862 RLQEELIVEGRQVRA------LEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQEL- 1934
Cdd:COG1566     55 RVTEVLVKEGDRVKKgqvlarLDPTDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELe 134

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1935 --EALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELScTLEASTATLQATLDTCQARARQLE 2008
Cdd:COG1566    135 ryQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQLAQAQAGLREEEELA-AAQAQVAQAEAALAQAELNLARTT 209
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1796-2293 5.45e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 5.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1796 QLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQahvtlKERQGELEEHRGQVQRLQEELivegrqvR 1875
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK-----LEKLLQLLPLYQELEALEAEL-------A 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1876 ALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQA 1955
Cdd:COG4717    143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1956 EALQEALSKAQATLQ-EKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQ 2034
Cdd:COG4717    223 EELEEELEQLENELEaAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2035 ELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEeetrglLESLKELQLTVAQKEEEILMLREAQQRQN-- 2112
Cdd:COG4717    303 EAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDR------IEELQELLREAEELEEELQLEELEQEIAAll 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2113 QEASSPSHRSFpaEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASisslqeiamFLQASVLERE 2192
Cdd:COG4717    377 AEAGVEDEEEL--RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE---------ELEEELEELE 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2193 SEQQRLQEELVLSRQALEEQQSRGphsssradqgpkagqdtepgevieaepspgvgEKEQLRQRLERLQQAVAELEVDRS 2272
Cdd:COG4717    446 EELEELREELAELEAELEQLEEDG--------------------------------ELAELLQELEELKAELRELAEEWA 493

                          490       500
                   ....*....|....*....|.
gi 1958767515 2273 KLQCHNAQLRTTLEQVERERR 2293
Cdd:COG4717    494 ALKLALELLEEAREEYREERL 514
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1734-2113 6.06e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 42.09  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1734 QERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQV--LQGQ--------------- 1796
Cdd:PRK10246   432 HGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIkdLEAQraqlqagqpcplcgs 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1797 -------------LEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKtsaLQAALEQAHVTLKERQGELEEHRGQVQRL 1863
Cdd:PRK10246   512 tshpaveayqalePGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQ---LQRDESEAQSLRQEEQALTQQWQAVCASL 588

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1864 QEELivegrqvrALEEVLGDLRAESREHEKTVLALQQRCAEQAQ--EHEAEARTLQDSWLQAQATLAEQEQELEALRAEN 1941
Cdd:PRK10246   589 NITL--------QPQDDIQPWLDAQEEHERQLRLLSQRHELQGQiaAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQE 660

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1942 qysrQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQ 2021
Cdd:PRK10246   661 ----DEEASWLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQCLSLHSQLQTL 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2022 ALQHQEAMQHLQQELCQKEEDLRQQ--DEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEE 2099
Cdd:PRK10246   737 QQQDVLEAQRLQKAQAQFDTALQASvfDDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPD 816

                          410
                   ....*....|....
gi 1958767515 2100 EILMLREAQQRQNQ 2113
Cdd:PRK10246   817 GLDLTVTVEQIQQE 830
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1794-2049 6.71e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.71  E-value: 6.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1794 QGQLEEAQRALAQRDHELEALRQEQQQtrgqEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLqeELIVEGRQ 1873
Cdd:PRK10246   218 VQSLTASLQVLTDEEKQLLTAQQQQQQ----SLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAAL--SLAQPARQ 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1874 VRALEEvlgdlraESREHEKTVLALQQRCAE---QAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEE- 1949
Cdd:PRK10246   292 LRPHWE-------RIQEQSAALAHTRQQIEEvntRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1950 -----AAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQ 2024
Cdd:PRK10246   365 lagwrAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQ 444

                          250       260
                   ....*....|....*....|....*
gi 1958767515 2025 HQEAMQHLQQELCQKEEDLRQQDEQ 2049
Cdd:PRK10246   445 LQVAIQNVTQEQTQRNAALNEMRQR 469
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1278-2033 6.74e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 6.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1278 ELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVT 1357
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1358 EARAQASAagvLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQ 1437
Cdd:pfam01576   86 EEEERSQQ---LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1438 ELEKQ-REMQKAALELLSLDLKKRSREVDlqqeqiqeleqcrsvlehlpmaVQEREQKLSVQRDQIRELENDREAQRTAL 1516
Cdd:pfam01576  163 EFTSNlAEEEEKAKSLSKLKNKHEAMISD----------------------LEERLKKEEKGRQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1517 EHQLLDLEQKAQVIESQRGQIQD-LKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQE 1595
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEeLQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEE 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1596 LQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKgqelvlQKERIQVLEDQRTlQTKILEE 1675
Cdd:pfam01576  301 LEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQK------HTQALEELTEQLE-QAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1676 DLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVecqqeriQELQEHMGQLEQQLQGLH 1755
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR-------AELAEKLSKLQSELESVS 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1756 RKVGETSLLLTHREQETATLQQRLQEAKEqgelreqvlqgQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSAL 1835
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQE-----------LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNV 515

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1836 QAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEaRT 1915
Cdd:pfam01576  516 ERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ-RQ 594

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1916 LQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELsctLEASTATLQA 1995
Cdd:pfam01576  595 LVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQ---LRAEMEDLVS 671

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1958767515 1996 TLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQ 2033
Cdd:pfam01576  672 SKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQ 709
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1756-1940 6.77e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 6.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1756 RKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSAL 1835
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1836 QAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAE-QAQEHEAEAR 1914
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKElEEQLESLQEE 165

                          170       180
                   ....*....|....*....|....*.
gi 1958767515 1915 TLQDSWLQAQATLAEQEQELEALRAE 1940
Cdd:COG4372    166 LAALEQELQALSEAEAEQALDELLKE 191
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1949-2297 7.73e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1949 EAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEastatlqaTLDTCQARARQLEEALRVREGEIqtqalqHQEA 2028
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREYEGYELLKEKEA------LERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2029 MQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGiQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEI-LMLREA 2107
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIaEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2108 QQRQNQEASSPSHRS---FPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFL 2184
Cdd:TIGR02169  318 EDAEERLAKLEAEIDkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2185 QASVLERESEQQRLQEELVLSRQALEEQQsrgphsssradqgpkagqdtEPGEVIEAEPSPGVGEKEQLRQRLERLQQAV 2264
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLN--------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958767515 2265 AELEVDRSKLQCHNAQLRTTLEQVERERRKLKR 2297
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1589-1949 8.13e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 8.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1589 LEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQEL--------VLQKERIQ 1660
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYkelsasseELSEEKDA 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1661 VLEDQRTLQTKILEedLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQEL 1740
Cdd:pfam07888  120 LLAQRAAHEARIRE--LEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQEL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1741 QEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEqgelreqvLQGQLEEAQRALAQRDHELEALrqEQQQ 1820
Cdd:pfam07888  198 RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRS--------LQERLNASERKVEGLGEELSSM--AAQR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1821 TRGQEESMKQKTSALQAALEQAHVTLKERQG------ELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAEsREHEKT 1894
Cdd:pfam07888  268 DRTQAELHQARLQAAQLTLQLADASLALREGrarwaqERETLQQSAEADKDRIEKLSAELQRLEERLQEERME-REKLEV 346

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1895 VLALQQRCAE-QAQEHEAEARTLQDSWLQAQatlAEQEQELEALRAENQYSRQQEE 1949
Cdd:pfam07888  347 ELGREKDCNRvQLSESRRELQELKASLRVAQ---KEKEQLQAEKQELLEYIRQLEQ 399
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 672-901 8.16e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  672 AEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVER 751
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  752 D----RQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKclklELDTERSHAEQER 827
Cdd:COG4942     98 EleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA----ELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958767515  828 DAVARQLAQAEQEgQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTlETLERERTELEMKLREQHTETEA 901
Cdd:COG4942    174 AELEALLAELEEE-RAALEALKAERQKLLARLEKELAELAAELAELQQEA-EELEALIARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1734-1970 8.27e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 8.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1734 QERIQELQEHMGQLEQQLQGLHRKVGETSLllthrEQETATLQQRLQEakeqgelreqvLQGQLEEAQRALAQRDHELEA 1813
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGLVDL-----SEEAKLLLQQLSE-----------LESQLAEARAELAEAEARLAA 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1814 LRQEQQQTRGQeesmkqktsalqAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEK 1893
Cdd:COG3206    245 LRAQLGSGPDA------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1894 TVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQ 1970
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1873-2119 8.59e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1873 QVRALEEVLGDLRAESREHEKTVLALQQrcaeQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAF 1952
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1953 GQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLdtcqaraRQLEEALRVREGEIQTQALQHQEAMQHL 2032
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL-------KYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2033 QQELCQKEEDLRQQDEQRQLLEKAvaqrsqengIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQN 2112
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL---------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*..
gi 1958767515 2113 QEASSPS 2119
Cdd:COG4942    241 ERTPAAG 247
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
632-743 8.86e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 41.38  E-value: 8.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515  632 SRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQL 711
Cdd:COG5283     14 SALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQAGIDTRQLSAAQRRLRSSL 93

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1958767515  712 QQLHQDAERQEEALARAGQEKEALVRERAALE 743
Cdd:COG5283     94 EQTNRQLERQQQRLARLGARQDRLKAARARLQ 125
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
1765-2215 8.91e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 41.05  E-value: 8.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1765 LTHREQETATLQQRLQEAKE--QGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQA 1842
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSltADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRAR 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1843 HVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQ 1922
Cdd:COG5278    158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1923 AQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQAtldtcQA 2002
Cdd:COG5278    238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAA-----AA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2003 RARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRG 2082
Cdd:COG5278    313 AAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEV 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 2083 LLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQG 2162
Cdd:COG5278    393 LAIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVA 472

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958767515 2163 LALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSR 2215
Cdd:COG5278    473 ALAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAAL 525
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1382-2052 9.40e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.32  E-value: 9.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1382 LKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQtlsNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRS 1461
Cdd:PRK10246   213 LTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTR---LDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPA 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1462 REVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIReleNDREAQRTALEHQLLDLEQKAQVIESQRGQIQdlk 1541
Cdd:PRK10246   290 RQLRPHWERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIR---HHAAKQSAELQAQQQSLNTWLAEHDRFRQWNN--- 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1542 kQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQS----SQLHELENHSTRLAKEL 1617
Cdd:PRK10246   364 -ELAGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQrplrQRLVALHGQIVPQQKRL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1618 QERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELV------LQKERIQVLEDQRT-LQTKILEEDLEQIKHSLRERGQE 1690
Cdd:PRK10246   443 AQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLAdvkticEQEARIKDLEAQRAqLQAGQPCPLCGSTSHPAVEAYQA 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1691 L---ASQWQL--MQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLL 1765
Cdd:PRK10246   523 LepgVNQSRLdaLEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1766 THREQETATLQQRLQEAKEQGELREQvlQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESmkqkTSALQAALEQAHVT 1845
Cdd:PRK10246   603 DAQEEHERQLRLLSQRHELQGQIAAH--NQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDE----EASWLATRQQEAQS 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1846 LKERQGELEEHRGQVQRLQ---EELIVEGRQVRALEEVLGDlraESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQ 1922
Cdd:PRK10246   677 WQQRQNELTALQNRIQQLTpllETLPQSDDLPHSEETVALD---NWRQVHEQCLSLHSQLQTLQQQDVLEAQRLQKAQAQ 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1923 AQATLA-----EQEQELEALRAENQYSR--QQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQA 1995
Cdd:PRK10246   754 FDTALQasvfdDQQAFLAALLDEETLTQleQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQ 833

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958767515 1996 TldtcqarARQLEEAlRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQL 2052
Cdd:PRK10246   834 L-------AQQLREN-TTRQGEIRQQLKQDADNRQQQQALMQQIAQATQQVEDWGYL 882
PRK09039 PRK09039
peptidoglycan -binding protein;
1844-1979 9.65e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 9.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958767515 1844 VTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAeartlqdswlqA 1923
Cdd:PRK09039    46 REISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAA-----------A 114

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958767515 1924 QATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQ 1979
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRES 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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