probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X3 [Rattus norvegicus]
Protein Classification
glycosyltransferase family protein( domain architecture ID 229536)
glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Alg6_Alg8 super family | cl46505 | ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins ... |
74-267 | 3.04e-69 | ||||
ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. The actual alignment was detected with superfamily member pfam03155: Pssm-ID: 480845 Cd Length: 477 Bit Score: 221.60 E-value: 3.04e-69
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| Name | Accession | Description | Interval | E-value | ||||
| Alg6_Alg8 | pfam03155 | ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins ... |
74-267 | 3.04e-69 | ||||
ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. Pssm-ID: 460831 Cd Length: 477 Bit Score: 221.60 E-value: 3.04e-69
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| Name | Accession | Description | Interval | E-value | ||||
| Alg6_Alg8 | pfam03155 | ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins ... |
74-267 | 3.04e-69 | ||||
ALG6, ALG8 glycosyltransferase family; N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. Pssm-ID: 460831 Cd Length: 477 Bit Score: 221.60 E-value: 3.04e-69
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| Blast search parameters | ||||
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