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Conserved domains on  [gi|1958643932|ref|XP_038961857|]
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ankyrin repeat domain-containing protein 42 isoform X6 [Rattus norvegicus]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 12789823)

ankyrin (ANK) repeat domain-containing protein may be involved in mediating protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  17176038

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
21-150 1.36e-16

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.46  E-value: 1.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  21 ALKAFNDNGENVLDLAHRFLKQNIVQFIQGAeyeGSHLDDQDDLAF-PGHVAAFKGDLEMLKKLIDDGvINLNERDENGS 99
Cdd:COG0666    79 DINAKDDGGNTLLHAAARNGDLEIVKLLLEA---GADVNARDKDGEtPLHLAAYNGNLEIVKLLLEAG-ADVNAQDNDGN 154

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958643932 100 TPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:COG0666   155 TPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLL 205
PHA02874 super family cl31515
ankyrin repeat protein; Provisional
 37-274 1.97e-06

ankyrin repeat protein; Provisional


The actual alignment was detected with superfamily member PHA02874:

Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 48.81  E-value: 1.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  37 HRFLKQNIVQFIQGAEYEGSHLDDQDDLA-FPGHVAAFKGDLEMLKKLIDDGVInLNERDENGSTPMHKAAGQGHIDCLQ 115
Cdd:PHA02874  129 HYAIKKGDLESIKMLFEYGADVNIEDDNGcYPIHIAIKHNFFDIIKLLLEKGAY-ANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 116 WLVEMGadSNITNKAGERPSDVAKRFAH-LAAVKLLEGLQKYEIDDIEG------------DKNHISFFIRHgvegstda 182
Cdd:PHA02874  208 LLIDHG--NHIMNKCKNGFTPLHNAIIHnRSAIELLINNASINDQDIDGstplhhainppcDIDIIDILLYH-------- 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 183 KDDLSLSESDKANARMRAHKKIVELRQLLEIAESNF--KHLGGITEEDLKQKKELLESKKT---ITELQEQLayERLRRE 257
Cdd:PHA02874  278 KADISIKDNKGENPIDTAFKYINKDPVIKDIIANAVliKEADKLKDSDFLEHIEIKDNKEFsdfIKECNEEI--EDMKKT 355

                         250
                  ....*....|....*..
gi 1958643932 258 KLECQLDEYRVEVNQLK 274
Cdd:PHA02874  356 KCGCDKNIFDLCLIRIK 372
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
21-150 1.36e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.46  E-value: 1.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  21 ALKAFNDNGENVLDLAHRFLKQNIVQFIQGAeyeGSHLDDQDDLAF-PGHVAAFKGDLEMLKKLIDDGvINLNERDENGS 99
Cdd:COG0666    79 DINAKDDGGNTLLHAAARNGDLEIVKLLLEA---GADVNARDKDGEtPLHLAAYNGNLEIVKLLLEAG-ADVNAQDNDGN 154

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958643932 100 TPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:COG0666   155 TPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLL 205
Ank_2 pfam12796
Ankyrin repeats (3 copies);
69-150 1.60e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 59.74  E-value: 1.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGViNLNERDENGSTPMHKAAGQGHIDCLQWLVEmGADSNITNKaGERPSDVAKRFAHLAAVK 148
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGA-DANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKDN-GRTALHYAARSGHLEIVK 78


                  ..
gi 1958643932 149 LL 150
Cdd:pfam12796  79 LL 80
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 76-150 9.42e-08

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 53.13  E-value: 9.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  76 DLEMLKKLIDDGV---------------INLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKR 140
Cdd:PHA03100  155 DLKILKLLIDKGVdinaknrvnyllsygVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAIL 234

                          90
                  ....*....|
gi 1958643932 141 FAHLAAVKLL 150
Cdd:PHA03100  235 NNNKEIFKLL 244
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 37-274 1.97e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 48.81  E-value: 1.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  37 HRFLKQNIVQFIQGAEYEGSHLDDQDDLA-FPGHVAAFKGDLEMLKKLIDDGVInLNERDENGSTPMHKAAGQGHIDCLQ 115
Cdd:PHA02874  129 HYAIKKGDLESIKMLFEYGADVNIEDDNGcYPIHIAIKHNFFDIIKLLLEKGAY-ANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 116 WLVEMGadSNITNKAGERPSDVAKRFAH-LAAVKLLEGLQKYEIDDIEG------------DKNHISFFIRHgvegstda 182
Cdd:PHA02874  208 LLIDHG--NHIMNKCKNGFTPLHNAIIHnRSAIELLINNASINDQDIDGstplhhainppcDIDIIDILLYH-------- 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 183 KDDLSLSESDKANARMRAHKKIVELRQLLEIAESNF--KHLGGITEEDLKQKKELLESKKT---ITELQEQLayERLRRE 257
Cdd:PHA02874  278 KADISIKDNKGENPIDTAFKYINKDPVIKDIIANAVliKEADKLKDSDFLEHIEIKDNKEFsdfIKECNEEI--EDMKKT 355

                         250
                  ....*....|....*..
gi 1958643932 258 KLECQLDEYRVEVNQLK 274
Cdd:PHA02874  356 KCGCDKNIFDLCLIRIK 372
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 97-126 2.84e-04

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 37.57  E-value: 2.84e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 1958643932   97 NGSTPMHKAAGQGHIDCLQWLVEMGADSNI 126
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
21-150 1.36e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.46  E-value: 1.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  21 ALKAFNDNGENVLDLAHRFLKQNIVQFIQGAeyeGSHLDDQDDLAF-PGHVAAFKGDLEMLKKLIDDGvINLNERDENGS 99
Cdd:COG0666    79 DINAKDDGGNTLLHAAARNGDLEIVKLLLEA---GADVNARDKDGEtPLHLAAYNGNLEIVKLLLEAG-ADVNAQDNDGN 154

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958643932 100 TPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:COG0666   155 TPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLL 205
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
21-150 4.37e-14

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 71.14  E-value: 4.37e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  21 ALKAFNDNGENVLDLAHRFLKQNIVQFIQGAEYEGSHLDDQDDLAFpgHVAAFKGDLEMLKKLIDDGvINLNERDENGST 100
Cdd:COG0666    46 ALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLL--HAAARNGDLEIVKLLLEAG-ADVNARDKDGET 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1958643932 101 PMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:COG0666   123 PLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLL 172
Ank_2 pfam12796
Ankyrin repeats (3 copies);
69-150 1.60e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 59.74  E-value: 1.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGViNLNERDENGSTPMHKAAGQGHIDCLQWLVEmGADSNITNKaGERPSDVAKRFAHLAAVK 148
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGA-DANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKDN-GRTALHYAARSGHLEIVK 78


                  ..
gi 1958643932 149 LL 150
Cdd:pfam12796  79 LL 80
Ank_4 pfam13637
Ankyrin repeats (many copies);
69-118 4.28e-11

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 57.28  E-value: 4.28e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGViNLNERDENGSTPMHKAAGQGHIDCLQWLV 118
Cdd:pfam13637   6 HAAAASGHLELLRLLLEKGA-DINAVDGNGETALHFAASNGNVEVLKLLL 54
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
12-150 1.95e-10

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 60.74  E-value: 1.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  12 LSRVNSAVQALKAFNDNGENVLDLAHRFLKQNIVQFIQGAEYEGSHLDDQDDLAFPGHVAAFKGDLEMLKKLIDDGVINL 91
Cdd:COG0666     1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958643932  92 NERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLL 139
Ank_2 pfam12796
Ankyrin repeats (3 copies);
69-128 6.99e-10

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 55.12  E-value: 6.99e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGVINLnerDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITN 128
Cdd:pfam12796  35 HLAAKNGHLEIVKLLLEHADVNL---KDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
Ank_5 pfam13857
Ankyrin repeats (many copies);
83-138 5.74e-09

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 51.58  E-value: 5.74e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958643932  83 LIDDGVINLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVA 138
Cdd:pfam13857   1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
Ank_4 pfam13637
Ankyrin repeats (many copies);
98-150 3.71e-08

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 49.20  E-value: 3.71e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958643932  98 GSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 76-150 9.42e-08

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 53.13  E-value: 9.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  76 DLEMLKKLIDDGV---------------INLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKR 140
Cdd:PHA03100  155 DLKILKLLIDKGVdinaknrvnyllsygVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAIL 234

                          90
                  ....*....|
gi 1958643932 141 FAHLAAVKLL 150
Cdd:PHA03100  235 NNNKEIFKLL 244
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 69-166 2.13e-07

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 52.21  E-value: 2.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAfKGDLEMLKKLIDDGViNLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVK 148
Cdd:PTZ00322   88 QLAA-SGDAVGARILLTGGA-DPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165

                          90
                  ....*....|....*...
gi 1958643932 149 LLEGlqkYEIDDIEGDKN 166
Cdd:PTZ00322  166 LLSR---HSQCHFELGAN 180
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 69-150 2.85e-07

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 51.50  E-value: 2.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGViNLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVK 148
Cdd:PHA02874  129 HYAIKKGDLESIKMLFEYGA-DVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIK 207


                  ..
gi 1958643932 149 LL 150
Cdd:PHA02874  208 LL 209
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 37-274 1.97e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 48.81  E-value: 1.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  37 HRFLKQNIVQFIQGAEYEGSHLDDQDDLA-FPGHVAAFKGDLEMLKKLIDDGVInLNERDENGSTPMHKAAGQGHIDCLQ 115
Cdd:PHA02874  129 HYAIKKGDLESIKMLFEYGADVNIEDDNGcYPIHIAIKHNFFDIIKLLLEKGAY-ANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 116 WLVEMGadSNITNKAGERPSDVAKRFAH-LAAVKLLEGLQKYEIDDIEG------------DKNHISFFIRHgvegstda 182
Cdd:PHA02874  208 LLIDHG--NHIMNKCKNGFTPLHNAIIHnRSAIELLINNASINDQDIDGstplhhainppcDIDIIDILLYH-------- 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932 183 KDDLSLSESDKANARMRAHKKIVELRQLLEIAESNF--KHLGGITEEDLKQKKELLESKKT---ITELQEQLayERLRRE 257
Cdd:PHA02874  278 KADISIKDNKGENPIDTAFKYINKDPVIKDIIANAVliKEADKLKDSDFLEHIEIKDNKEFsdfIKECNEEI--EDMKKT 355

                         250
                  ....*....|....*..
gi 1958643932 258 KLECQLDEYRVEVNQLK 274
Cdd:PHA02874  356 KCGCDKNIFDLCLIRIK 372
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 97-129 1.35e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 41.51  E-value: 1.35e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1958643932  97 NGSTPMHKAAGQ-GHIDCLQWLVEMGADSNITNK 129
Cdd:pfam00023   1 DGNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 71-158 8.61e-05

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 44.09  E-value: 8.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958643932  71 AAFKGDLEMLKKLIDDGvINLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADsnitnkagerpSDVAKRFAHLAAVKLL 150
Cdd:PLN03192  629 AAKRNDLTAMKELLKQG-LNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGAD-----------VDKANTDDDFSPTELR 696


                  ....*...
gi 1958643932 151 EGLQKYEI 158
Cdd:PLN03192  697 ELLQKREL 704
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 97-126 2.41e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 37.62  E-value: 2.41e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958643932  97 NGSTPMHKAAGQGHIDCLQWLVEMGADSNI 126
Cdd:pfam13606   1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 97-126 2.84e-04

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 37.57  E-value: 2.84e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 1958643932   97 NGSTPMHKAAGQGHIDCLQWLVEMGADSNI 126
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 78-150 1.14e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 40.33  E-value: 1.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958643932  78 EMLKKLIDDGvINLNERDENGSTPMHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLL 150
Cdd:PHA02874  105 DMIKTILDCG-IDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLL 176
PHA03095 PHA03095
ankyrin-like protein; Provisional
 77-150 1.14e-03

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 40.39  E-value: 1.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958643932  77 LEMLKKLIDDGViNLNERDENGSTPMHK-AAGQG-HIDCLQWLVEMGADSNITNKAGERPSDVAKRF--AHLAAVKLL 150
Cdd:PHA03095   97 LDVIKLLIKAGA-DVNAKDKVGRTPLHVyLSGFNiNPKVIRLLLRKGADVNALDLYGMTPLAVLLKSrnANVELLRLL 173
Ank_2 pfam12796
Ankyrin repeats (3 copies);
102-166 1.75e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 37.02  E-value: 1.75e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958643932 102 MHKAAGQGHIDCLQWLVEMGADSNITNKAGERPSDVAKRFAHLAAVKLLegLQKYEIDDIEGDKN 166
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLL--LEHADVNLKDNGRT 63
Ank_5 pfam13857
Ankyrin repeats (many copies);
69-105 6.48e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 34.24  E-value: 6.48e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1958643932  69 HVAAFKGDLEMLKKLIDDGViNLNERDENGSTPMHKA 105
Cdd:pfam13857  21 HVAAKYGALEIVRVLLAYGV-DLNLKDEEGLTALDLA 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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