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Conserved domains on  [gi|1958752144|ref|XP_038958828|]
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GON-4-like protein isoform X7 [Rattus norvegicus]

Protein Classification

PAH and CASP8AP2 domain-containing protein( domain architecture ID 10496266)

PAH and CASP8AP2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CASP8AP2 cd12202
Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of ...
 2117-2182 1.73e-35

Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of Caspase 8-associated protein 2 (CASP8AP2) / GON-4 like proteins. CASP8AP2 (aka Flice-Associated Huge Protein (FLASH)) is implicated in numerous gene regulatory roles including roles in embryogenesis, oncogenesis, down-regulation of replication-dependent histone genes, regulation of Caspase 8 activity at the death-inducing signaling complex (DISC), and as a useful marker in leukemia prognosis. Gon-4 is critical in Caenorhabditis elegans gonadogenesis. Danio rerio GON4 is a regulator of gene expression in hematopoietic development, possibly by repressing expression. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.


:

Pssm-ID: 213401  Cd Length: 66  Bit Score: 129.80  E-value: 1.73e-35
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958752144 2117 NSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTAC 2182
Cdd:cd12202      1 NNVIKSKGEKVVLWTRDADRVILTACQEKGASPKTFAALASKLGKKTPQEVSERFRQLMKLFHKSC 66
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1627-1672 3.36e-07

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


:

Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 48.57  E-value: 3.36e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958752144 1627 KYEDFLQIIYEFesNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFL 1672
Cdd:pfam02671    2 VYDEFLKILNDY--KQEIIDIAEVIARVSELLKGHPDLLEGFNTFL 45
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 950-1250 2.70e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  950 PGSKRFSRKAWRQKRPL-----VQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPS 1024
Cdd:PHA03247  2658 PGRVSRPRRARRLGRAAqasspPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1025 VGVCgedsfESPAALPAMPSGSEARTSFPWSESQsappsssapklmlPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAP 1104
Cdd:PHA03247  2738 APAP-----PAVPAGPATPGGPARPARPPTTAGP-------------PAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1105 II-HPTPVIFTVPATTVKVVSLGGGCNMIQPVTAA--VAPSPQTIPITTLL-----VNPTSfPCSLNQPLVASSISPLLV 1176
Cdd:PHA03247  2800 SPwDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqpTAPPPPPGPPPPSLplggsVAPGG-DVRRRPPSRSPAAKPAAP 2878

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752144 1177 SSNP---LALPVTSLPEEKAHVSLDIAEGKNAPQNPE-PKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESS 1250
Cdd:PHA03247  2879 ARPPvrrLARPAVSRSTESFALPPDQPERPPQPQAPPpPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1727-1753 1.03e-03

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


:

Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 38.56  E-value: 1.03e-03
                           10        20
                   ....*....|....*....|....*..
gi 1958752144 1727 DITELKTQMWQLLRGHDHLQDEFSIFF 1753
Cdd:pfam02671   19 DIAEVIARVSELLKGHPDLLEGFNTFL 45
 
Name Accession Description Interval E-value
CASP8AP2 cd12202
Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of ...
 2117-2182 1.73e-35

Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of Caspase 8-associated protein 2 (CASP8AP2) / GON-4 like proteins. CASP8AP2 (aka Flice-Associated Huge Protein (FLASH)) is implicated in numerous gene regulatory roles including roles in embryogenesis, oncogenesis, down-regulation of replication-dependent histone genes, regulation of Caspase 8 activity at the death-inducing signaling complex (DISC), and as a useful marker in leukemia prognosis. Gon-4 is critical in Caenorhabditis elegans gonadogenesis. Danio rerio GON4 is a regulator of gene expression in hematopoietic development, possibly by repressing expression. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 213401  Cd Length: 66  Bit Score: 129.80  E-value: 1.73e-35
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958752144 2117 NSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTAC 2182
Cdd:cd12202      1 NNVIKSKGEKVVLWTRDADRVILTACQEKGASPKTFAALASKLGKKTPQEVSERFRQLMKLFHKSC 66
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1627-1672 3.36e-07

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 48.57  E-value: 3.36e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958752144 1627 KYEDFLQIIYEFesNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFL 1672
Cdd:pfam02671    2 VYDEFLKILNDY--KQEIIDIAEVIARVSELLKGHPDLLEGFNTFL 45
PHA03247 PHA03247
large tegument protein UL36; Provisional
 950-1250 2.70e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  950 PGSKRFSRKAWRQKRPL-----VQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPS 1024
Cdd:PHA03247  2658 PGRVSRPRRARRLGRAAqasspPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1025 VGVCgedsfESPAALPAMPSGSEARTSFPWSESQsappsssapklmlPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAP 1104
Cdd:PHA03247  2738 APAP-----PAVPAGPATPGGPARPARPPTTAGP-------------PAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1105 II-HPTPVIFTVPATTVKVVSLGGGCNMIQPVTAA--VAPSPQTIPITTLL-----VNPTSfPCSLNQPLVASSISPLLV 1176
Cdd:PHA03247  2800 SPwDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqpTAPPPPPGPPPPSLplggsVAPGG-DVRRRPPSRSPAAKPAAP 2878

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752144 1177 SSNP---LALPVTSLPEEKAHVSLDIAEGKNAPQNPE-PKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESS 1250
Cdd:PHA03247  2879 ARPPvrrLARPAVSRSTESFALPPDQPERPPQPQAPPpPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1727-1753 1.03e-03

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 38.56  E-value: 1.03e-03
                           10        20
                   ....*....|....*....|....*..
gi 1958752144 1727 DITELKTQMWQLLRGHDHLQDEFSIFF 1753
Cdd:pfam02671   19 DIAEVIARVSELLKGHPDLLEGFNTFL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
2130-2174 7.05e-03

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 36.43  E-value: 7.05e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 1958752144  2130 WTREADRVILTMCQEQGaqPHTFSVISQQLGNKTPVEVSHRFREL 2174
Cdd:smart00717    4 WTEEEDELLIELVKKYG--KNNWEKIAKELPGRTAEQCRERWRNL 46
 
Name Accession Description Interval E-value
CASP8AP2 cd12202
Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of ...
 2117-2182 1.73e-35

Caspase 8-associated protein 2 myb-like domain; This domain is the SANT/myb-like domain of Caspase 8-associated protein 2 (CASP8AP2) / GON-4 like proteins. CASP8AP2 (aka Flice-Associated Huge Protein (FLASH)) is implicated in numerous gene regulatory roles including roles in embryogenesis, oncogenesis, down-regulation of replication-dependent histone genes, regulation of Caspase 8 activity at the death-inducing signaling complex (DISC), and as a useful marker in leukemia prognosis. Gon-4 is critical in Caenorhabditis elegans gonadogenesis. Danio rerio GON4 is a regulator of gene expression in hematopoietic development, possibly by repressing expression. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 213401  Cd Length: 66  Bit Score: 129.80  E-value: 1.73e-35
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958752144 2117 NSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTAC 2182
Cdd:cd12202      1 NNVIKSKGEKVVLWTRDADRVILTACQEKGASPKTFAALASKLGKKTPQEVSERFRQLMKLFHKSC 66
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1627-1672 3.36e-07

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 48.57  E-value: 3.36e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958752144 1627 KYEDFLQIIYEFesNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFL 1672
Cdd:pfam02671    2 VYDEFLKILNDY--KQEIIDIAEVIARVSELLKGHPDLLEGFNTFL 45
PHA03247 PHA03247
large tegument protein UL36; Provisional
 950-1250 2.70e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  950 PGSKRFSRKAWRQKRPL-----VQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPS 1024
Cdd:PHA03247  2658 PGRVSRPRRARRLGRAAqasspPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1025 VGVCgedsfESPAALPAMPSGSEARTSFPWSESQsappsssapklmlPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAP 1104
Cdd:PHA03247  2738 APAP-----PAVPAGPATPGGPARPARPPTTAGP-------------PAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1105 II-HPTPVIFTVPATTVKVVSLGGGCNMIQPVTAA--VAPSPQTIPITTLL-----VNPTSfPCSLNQPLVASSISPLLV 1176
Cdd:PHA03247  2800 SPwDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqpTAPPPPPGPPPPSLplggsVAPGG-DVRRRPPSRSPAAKPAAP 2878

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958752144 1177 SSNP---LALPVTSLPEEKAHVSLDIAEGKNAPQNPE-PKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESS 1250
Cdd:PHA03247  2879 ARPPvrrLARPAVSRSTESFALPPDQPERPPQPQAPPpPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
PAH pfam02671
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ...
 1727-1753 1.03e-03

Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.


Pssm-ID: 460645 [Multi-domain]  Cd Length: 45  Bit Score: 38.56  E-value: 1.03e-03
                           10        20
                   ....*....|....*....|....*..
gi 1958752144 1727 DITELKTQMWQLLRGHDHLQDEFSIFF 1753
Cdd:pfam02671   19 DIAEVIARVSELLKGHPDLLEGFNTFL 45
PHA03247 PHA03247
large tegument protein UL36; Provisional
 975-1233 1.54e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 1.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  975 PSPSVQPVFNPGKMATWPTQSE----VPPSNTVVQIPHLIQPAAVLQTLPGFPSVGVCGEDS----FESPAALPAMPSGS 1046
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASpagpLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRrrppSRSPAAKPAAPARP 2881

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1047 EARTsfpwseSQSAPPSSSAPKLMLPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAPIIHPTPVIFTVPATTVKVVS-- 1124
Cdd:PHA03247  2882 PVRR------LARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGep 2955

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1125 --------LGGGCNMIQPVTAAVAPSPQtiPITTLLVNPTSFPCSLNQPLVASSISPLLVSSNPLALPVTSL-----PEE 1191
Cdd:PHA03247  2956 sgavpqpwLGALVPGRVAVPRFRVPQPA--PSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKqtlwpPDD 3033

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958752144 1192 KAHVSLD---------IAEGKNAPQNPEPKIKP-QEPTPQCATVFSKEEPRS 1233
Cdd:PHA03247  3034 TEDSDADslfdsdserSDLEALDPLPPEPHDPFaHEPDPATPEAGARESPSS 3085
PHA03378 PHA03378
EBNA-3B; Provisional
 912-1241 2.84e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.13  E-value: 2.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  912 TAATETSTDQHLQKTSPVVGGDTQyplllPKGVVLKLKPGSKRFSRKAWRQKRPLVQKPLLIQPSPSVQPVFnpgKMATW 991
Cdd:PHA03378   582 TSQLASSAPSYAQTPWPVPHPSQT-----PEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVF---PTPHQ 653

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144  992 PTQSEVPP-SNTVVQIPHLiqpaavlqtlpgfpsvgvcgedsfespaalPAMPSGSEARTSFP--WSESQSAPPSSSAPK 1068
Cdd:PHA03378   654 PPQVEITPyKPTWTQIGHI------------------------------PYQPSPTGANTMLPiqWAPGTMQPPPRAPTP 703

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1069 LMLPSLGPSKFRKPyvRRKPTRRKGAKASPCVKPAPIIHPTPVIFTVPATTVKVVSLGGGCNMIQPVTAAVAPSPQTipi 1148
Cdd:PHA03378   704 MRPPAAPPGRAQRP--AAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQP--- 778

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958752144 1149 ttllvNPTSFPCSLNQPLVASSISPllvssNPLALPVTSLPEEKAHVSLDIAEGKNAPQNPEPKIKPQEPTPQCATVFSK 1228
Cdd:PHA03378   779 -----PPQAPPAPQQRPRGAPTPQP-----PPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALER 848

                          330
                   ....*....|...
gi 1958752144 1229 EEPRSWHPSADTG 1241
Cdd:PHA03378   849 QAAAGPTPSPGSG 861
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
2130-2174 7.05e-03

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 36.43  E-value: 7.05e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 1958752144  2130 WTREADRVILTMCQEQGaqPHTFSVISQQLGNKTPVEVSHRFREL 2174
Cdd:smart00717    4 WTEEEDELLIELVKKYG--KNNWEKIAKELPGRTAEQCRERWRNL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 2130-2175 7.80e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 36.40  E-value: 7.80e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958752144 2130 WTREADRVILTMCQEQGaqPHTFSVISQQLGNKTPVEVSHRFRELM 2175
Cdd:cd00167      2 WTEEEDELLLEAVKKYG--KNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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