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Conserved domains on  [gi|1958749603|ref|XP_038957859|]
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peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X3 [Rattus norvegicus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
89-319 2.11e-16

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 2.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHVVCTK-TDFIITASHDGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:COG2319   119 HTGAVRSVAFSPdGKTLASGSADGTVRLWD-LATG-KLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpgqcewiyCPGDAISSVAASEKST--------GKIFIYDGRGdNQPLHIFdKLHVSPLTQIRLNPVYKAVV 239
Cdd:COG2319   197 LRTLT------------GHTGAVRSVAFSPDGKllasgsadGTVRLWDLAT-GKLLRTL-TGHSGSVRSVAFSPDGRLLA 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 240 SSDKSGMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFD 319
Cdd:COG2319   263 SGSADGTV----------RL-----WDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
89-319 2.11e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 2.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHVVCTK-TDFIITASHDGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:COG2319   119 HTGAVRSVAFSPdGKTLASGSADGTVRLWD-LATG-KLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpgqcewiyCPGDAISSVAASEKST--------GKIFIYDGRGdNQPLHIFdKLHVSPLTQIRLNPVYKAVV 239
Cdd:COG2319   197 LRTLT------------GHTGAVRSVAFSPDGKllasgsadGTVRLWDLAT-GKLLRTL-TGHSGSVRSVAFSPDGRLLA 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 240 SSDKSGMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFD 319
Cdd:COG2319   263 SGSADGTV----------RL-----WDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 89-318 2.15e-15

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 75.06  E-value: 2.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHV-VCTKTDFIITASHDGHVKFWKKieEGIEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:cd00200     8 HTGGVTCVaFSPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGEC 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpGQCEWIYCPgdAIS---SVAASEKSTGKIFIYDGRgDNQPLHIFdKLHVSPLTQIRLNPVYKAVVSSDKS 244
Cdd:cd00200    86 VRTLT-----GHTSYVSSV--AFSpdgRILSSSSRDKTIKVWDVE-TGKCLTTL-RGHTDWVNSVAFSPDGTFVASSSQD 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958749603 245 GMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVF 318
Cdd:cd00200   157 GTI----------KL-----WDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTL 215
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 284-307 1.55e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 35.75  E-value: 1.55e-03
                           10        20
                   ....*....|....*....|....
gi 1958749603  284 TSICFSPDGKKIATIGSDRKVRIF 307
Cdd:smart00320  16 TSVAFSPDGKYLASGSDDGTIKLW 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
89-319 2.11e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 2.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHVVCTK-TDFIITASHDGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:COG2319   119 HTGAVRSVAFSPdGKTLASGSADGTVRLWD-LATG-KLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpgqcewiyCPGDAISSVAASEKST--------GKIFIYDGRGdNQPLHIFdKLHVSPLTQIRLNPVYKAVV 239
Cdd:COG2319   197 LRTLT------------GHTGAVRSVAFSPDGKllasgsadGTVRLWDLAT-GKLLRTL-TGHSGSVRSVAFSPDGRLLA 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 240 SSDKSGMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFD 319
Cdd:COG2319   263 SGSADGTV----------RL-----WDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
WD40 COG2319
WD40 repeat [General function prediction only];
89-318 2.13e-15

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 76.10  E-value: 2.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHVVCTKT-DFIITASHDGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:COG2319   161 HSGAVTSVAFSPDgKLLASGSDDGTVRLWD-LATG-KLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKL 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpGQCEWIYCPgdAISS-----VAASEksTGKIFIYDgRGDNQPLHIFDKlHVSPLTQIRLNPVYKAVVSSD 242
Cdd:COG2319   239 LRTLT-----GHSGSVRSV--AFSPdgrllASGSA--DGTVRLWD-LATGELLRTLTG-HSGGVNSVAFSPDGKLLASGS 307

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958749603 243 KSGMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVF 318
Cdd:COG2319   308 DDGTV----------RL-----WDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTL 368
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 89-318 2.15e-15

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 75.06  E-value: 2.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  89 HRDVITHV-VCTKTDFIITASHDGHVKFWKKieEGIEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDM 167
Cdd:cd00200     8 HTGGVTCVaFSPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGEC 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 168 INMLKlgyfpGQCEWIYCPgdAIS---SVAASEKSTGKIFIYDGRgDNQPLHIFdKLHVSPLTQIRLNPVYKAVVSSDKS 244
Cdd:cd00200    86 VRTLT-----GHTSYVSSV--AFSpdgRILSSSSRDKTIKVWDVE-TGKCLTTL-RGHTDWVNSVAFSPDGTFVASSSQD 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958749603 245 GMIeywtgppheyKFpktvnWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVF 318
Cdd:cd00200   157 GTI----------KL-----WDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTL 215
WD40 COG2319
WD40 repeat [General function prediction only];
104-319 8.23e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 65.32  E-value: 8.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 104 IITASHDGHVKFWKkIEEGIEfVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNfdminmlklgyfpGQCEW- 182
Cdd:COG2319    93 LASASADGTVRLWD-LATGLL-LRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLAT-------------GKLLRt 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 183 IYCPGDAISSVAASekSTGKIFI---YDGR------GDNQPLHIFDKlHVSPLTQIRLNP----VykAVVSSDksgmiey 249
Cdd:COG2319   158 LTGHSGAVTSVAFS--PDGKLLAsgsDDGTvrlwdlATGKLLRTLTG-HTGAVRSVAFSPdgklL--ASGSAD------- 225

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958749603 250 wtgppheykfpKTVN-WEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFD 319
Cdd:COG2319   226 -----------GTVRlWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT 285
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 88-308 2.09e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 60.43  E-value: 2.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  88 MHRDVITHVVCTKTDFIITASH-DGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNfd 166
Cdd:cd00200    91 GHTSYVSSVAFSPDGRILSSSSrDKTIKVWD-VETG-KCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRT-- 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 167 minmlklgyfpGQCEWIYcPG--DAISSVAASEK--------STGKIFIYDGRGDnQPLHIFDKlHVSPLTQIRLNPVYK 236
Cdd:cd00200   167 -----------GKCVATL-TGhtGEVNSVAFSPDgekllsssSDGTIKLWDLSTG-KCLGTLRG-HENGVNSVAFSPDGY 232

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958749603 237 AVVSSDKSGMIEYWtgppheykfpktvnwEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFR 308
Cdd:cd00200   233 LLASGSEDGTIRVW---------------DLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 72-172 1.08e-07

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 52.34  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603  72 VYLENLPSASMYERSYMHRDVITHVVCTKTDF-IITASHDGHVKFWKkIEEGiEFVKHFRSHLGIIESIAVSSEGALFCS 150
Cdd:cd00200   159 IKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEkLLSSSSDGTIKLWD-LSTG-KCLGTLRGHENGVNSVAFSPDGYLLAS 236

                          90       100
                  ....*....|....*....|..
gi 1958749603 151 VGDDKAMKVFDVVNFDMINMLK 172
Cdd:cd00200   237 GSEDGTIRVWDLRTGECVQTLS 258
WD40 COG2319
WD40 repeat [General function prediction only];
89-162 1.45e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.44  E-value: 1.45e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958749603  89 HRDVITHVVCTKTD-FIITASHDGHVKFWKKieEGIEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDV 162
Cdd:COG2319   329 HTGAVRSVAFSPDGkTLASGSDDGTVRLWDL--ATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 126-318 3.65e-05

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 44.63  E-value: 3.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 126 VKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLgyfpgqcewiycPGDAISSVAASekstgkifi 205
Cdd:cd00200     2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKG------------HTGPVRDVAAS--------- 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958749603 206 ydgrGDNQPLhifdklhvspltqirlnpvykAVVSSDKsgmieywtgppheykfpkTVN-WEYKTDTDLYEFAKCKAYPT 284
Cdd:cd00200    61 ----ADGTYL---------------------ASGSSDK------------------TIRlWDLETGECVRTLTGHTSYVS 97

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1958749603 285 SICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVF 318
Cdd:cd00200    98 SVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTL 131
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 284-307 1.55e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 35.75  E-value: 1.55e-03
                           10        20
                   ....*....|....*....|....
gi 1958749603  284 TSICFSPDGKKIATIGSDRKVRIF 307
Cdd:smart00320  16 TSVAFSPDGKYLASGSDDGTIKLW 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 124-161 7.35e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 33.83  E-value: 7.35e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958749603  124 EFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFD 161
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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