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Conserved domains on  [gi|1958809539|ref|XP_038956384|]
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protein ripply1 isoform X1 [Rattus norvegicus]

Protein Classification

Ripply domain-containing protein( domain architecture ID 10633203)

Ripply domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ripply pfam14998
Transcription Regulator; The precise function of this family is not clear, but it is thought ...
 116-190 8.87e-29

Transcription Regulator; The precise function of this family is not clear, but it is thought to play a role in somitogenesis, development and transcriptional repression. Ripply is also known by an alternative name, Bowline. Bowline, is an associate protein of the transcriptional co-repressor XGrg-4. This family contains two conserved sequence motifs: WRPW and FPVQATI. The WRPW motif is thought to be required for binding to tle/groucho proteins. Ripply3 is also known as Down Syndrome Critical Region Protein 6 homolog. This family of proteins is found in eukaryotes. Proteins in this family are typically between 109 and 154 amino acids in length.


:

Pssm-ID: 464433  Cd Length: 85  Bit Score: 103.89  E-value: 8.87e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958809539 116 LWRPWLSSINDQPRQARSLVDWAAGEATAAEAK-ADSEFHHPVRLYWPRSRSFDYLYSAGEILLHNFPVQATINLY 190
Cdd:pfam14998   1 LWRPWLLTPGDAERQGPCRAAPHSPGELAEPSRkKAQYFHHPVRLYWPKSKSYDYLYSAGEKLLRNFPVQATIHFY 76
 
Name Accession Description Interval E-value
Ripply pfam14998
Transcription Regulator; The precise function of this family is not clear, but it is thought ...
 116-190 8.87e-29

Transcription Regulator; The precise function of this family is not clear, but it is thought to play a role in somitogenesis, development and transcriptional repression. Ripply is also known by an alternative name, Bowline. Bowline, is an associate protein of the transcriptional co-repressor XGrg-4. This family contains two conserved sequence motifs: WRPW and FPVQATI. The WRPW motif is thought to be required for binding to tle/groucho proteins. Ripply3 is also known as Down Syndrome Critical Region Protein 6 homolog. This family of proteins is found in eukaryotes. Proteins in this family are typically between 109 and 154 amino acids in length.


Pssm-ID: 464433  Cd Length: 85  Bit Score: 103.89  E-value: 8.87e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958809539 116 LWRPWLSSINDQPRQARSLVDWAAGEATAAEAK-ADSEFHHPVRLYWPRSRSFDYLYSAGEILLHNFPVQATINLY 190
Cdd:pfam14998   1 LWRPWLLTPGDAERQGPCRAAPHSPGELAEPSRkKAQYFHHPVRLYWPKSKSYDYLYSAGEKLLRNFPVQATIHFY 76
 
Name Accession Description Interval E-value
Ripply pfam14998
Transcription Regulator; The precise function of this family is not clear, but it is thought ...
 116-190 8.87e-29

Transcription Regulator; The precise function of this family is not clear, but it is thought to play a role in somitogenesis, development and transcriptional repression. Ripply is also known by an alternative name, Bowline. Bowline, is an associate protein of the transcriptional co-repressor XGrg-4. This family contains two conserved sequence motifs: WRPW and FPVQATI. The WRPW motif is thought to be required for binding to tle/groucho proteins. Ripply3 is also known as Down Syndrome Critical Region Protein 6 homolog. This family of proteins is found in eukaryotes. Proteins in this family are typically between 109 and 154 amino acids in length.


Pssm-ID: 464433  Cd Length: 85  Bit Score: 103.89  E-value: 8.87e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958809539 116 LWRPWLSSINDQPRQARSLVDWAAGEATAAEAK-ADSEFHHPVRLYWPRSRSFDYLYSAGEILLHNFPVQATINLY 190
Cdd:pfam14998   1 LWRPWLLTPGDAERQGPCRAAPHSPGELAEPSRkKAQYFHHPVRLYWPKSKSYDYLYSAGEKLLRNFPVQATIHFY 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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