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Conserved domains on  [gi|1958757722|ref|XP_038954845|]
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blood vessel epicardial substance isoform X1 [Rattus norvegicus]

Protein Classification

popeye domain-containing protein( domain architecture ID 10521971)

popeye domain-containing protein similar to blood vessel epicardial substance, a cell adhesion molecule involved in the establishment and/or maintenance of cell integrity

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Popeye pfam04831
Popeye protein conserved region; The function of Popeye proteins is not well understood. They ...
41-266 6.91e-100

Popeye protein conserved region; The function of Popeye proteins is not well understood. They are predominantly expressed in cardiac and skeletal muscle. This family represents a conserved region which includes three potential transmembrane domains.


:

Pssm-ID: 461448  Cd Length: 227  Bit Score: 294.52  E-value: 6.91e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722  41 HHLVFHAANVCFAVGLLIPTTLHlHMILLRVMLSIGCTLYVVWATLYRCALDMMIWNSVFLGINILHLSYLLYKKRPVKI 120
Cdd:pfam04831   2 QHALFHLANILLLLGFLGPSGFY-GLLYLRAFLGLGFLLFALWAWLVVCAPDIFLWNFLLVLINLLQLLHLLYRLRPVTF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722 121 EKDLGGVYHRLFEPLRVPPDLFRRLTG-QFCVIQTLKRGQVYATEDKTSVDDRLSILLKGRMKVSYrGHFLHNIYPCAFI 199
Cdd:pfam04831  81 PPELEDLYKTLFQPLGVSRKQFKKLVScCEAQILTLKKGEAYAVEGKTPIDRLSLLLSGRLLVVTN-GQFLHHIIPYQFL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958757722 200 DSPEFRSTQMHKGEKFQVTIVADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLND 266
Cdd:pfam04831 160 DSPEWESLRPSEEDKFQVTITAEEDCRYLCWPREKLEYLLAKERYLARVFSNLIGKDITEKLYSLNE 226
 
Name Accession Description Interval E-value
Popeye pfam04831
Popeye protein conserved region; The function of Popeye proteins is not well understood. They ...
41-266 6.91e-100

Popeye protein conserved region; The function of Popeye proteins is not well understood. They are predominantly expressed in cardiac and skeletal muscle. This family represents a conserved region which includes three potential transmembrane domains.


Pssm-ID: 461448  Cd Length: 227  Bit Score: 294.52  E-value: 6.91e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722  41 HHLVFHAANVCFAVGLLIPTTLHlHMILLRVMLSIGCTLYVVWATLYRCALDMMIWNSVFLGINILHLSYLLYKKRPVKI 120
Cdd:pfam04831   2 QHALFHLANILLLLGFLGPSGFY-GLLYLRAFLGLGFLLFALWAWLVVCAPDIFLWNFLLVLINLLQLLHLLYRLRPVTF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722 121 EKDLGGVYHRLFEPLRVPPDLFRRLTG-QFCVIQTLKRGQVYATEDKTSVDDRLSILLKGRMKVSYrGHFLHNIYPCAFI 199
Cdd:pfam04831  81 PPELEDLYKTLFQPLGVSRKQFKKLVScCEAQILTLKKGEAYAVEGKTPIDRLSLLLSGRLLVVTN-GQFLHHIIPYQFL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958757722 200 DSPEFRSTQMHKGEKFQVTIVADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLND 266
Cdd:pfam04831 160 DSPEWESLRPSEEDKFQVTITAEEDCRYLCWPREKLEYLLAKERYLARVFSNLIGKDITEKLYSLNE 226
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
132-252 1.98e-05

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 44.98  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722 132 FEPLrvPPDLFRRLTgQFCVIQTLKRGQVYATEDKTSvdDRLSILLKGRMKVSY-----RGHFLHNIYPCAFIDSPEFRS 206
Cdd:COG0664     1 FAGL--SDEELEALL-AHLELRTLKKGEVLFREGDPA--DHLYFVLSGLVKLYRisedgREQILGFLGPGDFFGELSLLG 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958757722 207 tqmhkGEKFQVTIVADDNCRFLCWSRERLTYFLESEP-FLYEIFRYL 252
Cdd:COG0664    76 -----GEPSPATAEALEDSELLRIPREDLEELLERNPeLARALLRLL 117
 
Name Accession Description Interval E-value
Popeye pfam04831
Popeye protein conserved region; The function of Popeye proteins is not well understood. They ...
41-266 6.91e-100

Popeye protein conserved region; The function of Popeye proteins is not well understood. They are predominantly expressed in cardiac and skeletal muscle. This family represents a conserved region which includes three potential transmembrane domains.


Pssm-ID: 461448  Cd Length: 227  Bit Score: 294.52  E-value: 6.91e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722  41 HHLVFHAANVCFAVGLLIPTTLHlHMILLRVMLSIGCTLYVVWATLYRCALDMMIWNSVFLGINILHLSYLLYKKRPVKI 120
Cdd:pfam04831   2 QHALFHLANILLLLGFLGPSGFY-GLLYLRAFLGLGFLLFALWAWLVVCAPDIFLWNFLLVLINLLQLLHLLYRLRPVTF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722 121 EKDLGGVYHRLFEPLRVPPDLFRRLTG-QFCVIQTLKRGQVYATEDKTSVDDRLSILLKGRMKVSYrGHFLHNIYPCAFI 199
Cdd:pfam04831  81 PPELEDLYKTLFQPLGVSRKQFKKLVScCEAQILTLKKGEAYAVEGKTPIDRLSLLLSGRLLVVTN-GQFLHHIIPYQFL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958757722 200 DSPEFRSTQMHKGEKFQVTIVADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLND 266
Cdd:pfam04831 160 DSPEWESLRPSEEDKFQVTITAEEDCRYLCWPREKLEYLLAKERYLARVFSNLIGKDITEKLYSLNE 226
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
132-252 1.98e-05

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 44.98  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958757722 132 FEPLrvPPDLFRRLTgQFCVIQTLKRGQVYATEDKTSvdDRLSILLKGRMKVSY-----RGHFLHNIYPCAFIDSPEFRS 206
Cdd:COG0664     1 FAGL--SDEELEALL-AHLELRTLKKGEVLFREGDPA--DHLYFVLSGLVKLYRisedgREQILGFLGPGDFFGELSLLG 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958757722 207 tqmhkGEKFQVTIVADDNCRFLCWSRERLTYFLESEP-FLYEIFRYL 252
Cdd:COG0664    76 -----GEPSPATAEALEDSELLRIPREDLEELLERNPeLARALLRLL 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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