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Conserved domains on  [gi|1958680723|ref|XP_038949484|]
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FMR1-interacting protein NUFIP1 isoform X1 [Rattus norvegicus]

Protein Classification

nuclear FMR1 interacting 1 family protein( domain architecture ID 10564535)

nuclear FMR1 interacting protein 1 (NUFIP1) family protein functions in the assembly of the large subunit of the ribosome and in telomere maintenance

Gene Ontology:  GO:0000027|GO:0042254
PubMed:  35326495

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NUFIP1 pfam10453
Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family ...
 1-49 5.78e-17

Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family have been implicated in the assembly of the large subunit of the ribosome and in telomere maintenance. Some proteins in this family contain a CCCH zinc finger. This family contains a protein called human fragile X mental retardation-interacting protein 1, which is known to bind RNA and is phosphorylated upon DNA damage.


:

Pssm-ID: 463096 [Multi-domain]  Cd Length: 53  Bit Score: 73.03  E-value: 5.78e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1958680723   1 MHAPGmKKIKLDTPEDIARWREERRKNYPTLANIERKKLLQLEKEKRGE 49
Cdd:pfam10453   6 VKIPG-TSITLETPEDIAKWIEERRKNWPTKINIEKKKKMEEEKIKRGE 53
 
Name Accession Description Interval E-value
NUFIP1 pfam10453
Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family ...
 1-49 5.78e-17

Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family have been implicated in the assembly of the large subunit of the ribosome and in telomere maintenance. Some proteins in this family contain a CCCH zinc finger. This family contains a protein called human fragile X mental retardation-interacting protein 1, which is known to bind RNA and is phosphorylated upon DNA damage.


Pssm-ID: 463096 [Multi-domain]  Cd Length: 53  Bit Score: 73.03  E-value: 5.78e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1958680723   1 MHAPGmKKIKLDTPEDIARWREERRKNYPTLANIERKKLLQLEKEKRGE 49
Cdd:pfam10453   6 VKIPG-TSITLETPEDIAKWIEERRKNWPTKINIEKKKKMEEEKIKRGE 53
 
Name Accession Description Interval E-value
NUFIP1 pfam10453
Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family ...
 1-49 5.78e-17

Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1); Proteins in this family have been implicated in the assembly of the large subunit of the ribosome and in telomere maintenance. Some proteins in this family contain a CCCH zinc finger. This family contains a protein called human fragile X mental retardation-interacting protein 1, which is known to bind RNA and is phosphorylated upon DNA damage.


Pssm-ID: 463096 [Multi-domain]  Cd Length: 53  Bit Score: 73.03  E-value: 5.78e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1958680723   1 MHAPGmKKIKLDTPEDIARWREERRKNYPTLANIERKKLLQLEKEKRGE 49
Cdd:pfam10453   6 VKIPG-TSITLETPEDIAKWIEERRKNWPTKINIEKKKKMEEEKIKRGE 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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