|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
45-173 |
1.76e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
:
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 45 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 124
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678989 125 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 173
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 super family |
cl33186 |
104 kDa microneme/rhoptry antigen; Provisional |
965-1309 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
The actual alignment was detected with superfamily member PTZ00449:
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 965 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1043
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1044 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1123
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1124 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1203
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1204 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1277
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678989 1278 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1309
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
187-634 |
2.38e-08 |
|
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 2.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 187 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 266
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 267 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 338
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 339 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 418
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 419 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 495
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 496 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 574
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 575 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 634
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
45-173 |
1.76e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 45 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 124
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678989 125 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 173
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
965-1309 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 965 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1043
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1044 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1123
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1124 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1203
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1204 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1277
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678989 1278 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1309
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
187-634 |
2.38e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 2.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 187 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 266
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 267 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 338
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 339 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 418
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 419 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 495
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 496 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 574
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 575 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 634
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
812-1255 |
1.81e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 812 PPVNAKFSIMPAWQKFSDSGAETFKQSTDGESVRKKPGPAPSEETTPTP--------QPLPAGA-----PELQKNLEKQE 878
Cdd:pfam03154 207 PPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpppsqvspQPLPQPSlhgqmPPMPHSLQTGP 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 879 VSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDPAMPGGEEKASPFGIKLRRTNYSLRF 958
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 959 HCDQQAEQKKKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAvHPGLPPASG 1038
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ-SQSLPPPAA 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1039 QTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHivelltrragkldSEPSEPAKENQESRDSQPPSPSL 1118
Cdd:pfam03154 446 SHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAM-------------PGIQPPSSASVSSSGPVPAAVSC 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1119 LEEPKGQKRDEKDVLEKKPASPPLPSSQQERPSL--TP----ETGRKEKPMLQSRHS----------LDGSKLTEKAETA 1182
Cdd:pfam03154 513 PLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVvnTPshasQSARFYKHLDRGYNScartdlyfmpLAGSKLAKKREEA 592
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958678989 1183 QPLWITLALQKQKGFREQQATRE-ERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHkpAAPSEEKKPET 1255
Cdd:pfam03154 593 LEKAKREAEQKAREEKEREKEKEkEREREREREREAERAAKASSSSHEGRMGDPQLAGPAH--MRPSFEPPPTT 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
218-532 |
2.41e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 218 HEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERrlweeslrqelLEEEEEEAEEVGLLLQAGKAPPEEGPQS 297
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-----------LELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 298 GLEEQRGSEQELGEADdptrleaEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELR 377
Cdd:COG1196 307 LEERRRELEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 378 QREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAERH 457
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958678989 458 EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDA 532
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
45-173 |
1.76e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 45 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 124
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678989 125 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 173
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
965-1309 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 965 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1043
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1044 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1123
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1124 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1203
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1204 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1277
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678989 1278 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1309
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
187-634 |
2.38e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 2.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 187 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 266
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 267 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 338
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 339 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 418
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 419 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 495
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 496 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 574
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 575 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 634
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
848-1155 |
1.17e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.40 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 848 PGPAPSEETTPTPQPLP-AGAPELQKNLEKQEVSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTS 926
Cdd:PHA03247 2559 APPAAPDRSVPPPRPAPrPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 927 DVGSPDPAMPGGEEKASPFGIKLRRTNYSLRfhcdqqaeqkkKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERR 1006
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARR-----------LGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1007 PALAPRR-DSAESHPSGHCVAAAVHPGlPPASGQTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHIVE 1085
Cdd:PHA03247 2708 PEPAPHAlVSATPLPPGPAAARQASPA-LPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1086 LLTRRAGKLDSEPSEPAKenqesrdSQPPSPSLLEEPKgqkrdEKDVLEKKPASPPLPSSQQERPSLTPE 1155
Cdd:PHA03247 2787 AVASLSESRESLPSPWDP-------ADPPAAVLAPAAA-----LPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
148-641 |
2.25e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 2.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 148 AIARLDNSAAKHKLSVKPKNQRVSRKHRWLAQDRQNAPGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDY 227
Cdd:PTZ00121 1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 228 WRELEAKCK----KQKAEAAeKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQSglEEQR 303
Cdd:PTZ00121 1308 KKKAEEAKKadeaKKKAEEA-KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA--DAAK 1384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 304 GSEQELGEADDPTRLEAEERRREQEKAERQAEKlrqreeaerqeeelRQREEAERQAEELRQREEAERQEEELRQREaen 383
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAK--------------KKADEAKKKAEEKKKADEAKKKAEEAKKAD--- 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 384 qEEKLRQREAEKQEEEVRQREVEGQEEELKQR--EAKRQEEELRQLEEAERQ--EKLRQREAQKQEEEELRQREAERHEK 459
Cdd:PTZ00121 1448 -EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKaeEAKKADEAKKKAEEAKKKadEAKKAAEAKKKADEAKKAEEAKKADE 1526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 460 LRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLV---EEGSQGPEGESQPWLTDDADQQS 536
Cdd:PTZ00121 1527 AKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaEEAKKAEEARIEEVMKLYEEEKK 1606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 537 PLQRDLEKpgEREDLVSAGQRDIPEDQRGEVEMAIEPVEQsgdwgahfggvdgvdvEGKEASQIdnpqpqERQKEGTPAR 616
Cdd:PTZ00121 1607 MKAEEAKK--AEEAKIKAEELKKAEEEKKKVEQLKKKEAE----------------EKKKAEEL------KKAEEENKIK 1662
|
490 500
....*....|....*....|....*.
gi 1958678989 617 EEKEATAADID-RKVEELRWQEVDER 641
Cdd:PTZ00121 1663 AAEEAKKAEEDkKKAEEAKKAEEDEK 1688
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
202-640 |
8.89e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 8.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 202 EDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVG 281
Cdd:PTZ00121 1150 DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV 1229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 282 LLLQAGKAPPEEGPQSglEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAE 361
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKA--EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 362 ELRQREEAERQEEELRQREAENQEEKLRQR-EAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQRE 440
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKKKaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 441 AQKQEEEELRQREAERHEKL----RQHEAERQEEELRQRERQRAQEEEAKRmlqEEEEAKHIEELKGR--EKEAPEPLVE 514
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDKKKAdelkKAAAAKKKADEAKKKAEEKKKADEAKK---KAEEAKKADEAKKKaeEAKKAEEAKK 1464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 515 EGSQGPEGESQPWLTDDADQQSPLQRDLEKPGER-EDLVSAGQRDIPEDQRGEVEMAIEPVEQSgdwgahfggvdgvdvE 593
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAK---------------K 1529
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1958678989 594 GKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELRWQEVDE 640
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
217-655 |
1.32e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 217 SHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRlweeSLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQ 296
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK----KKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 297 SGLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKlrQREEAERQEEELRQREEAERQAEELRQREEAERQEEEL 376
Cdd:PTZ00121 1438 KKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKK--KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 377 RQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAER 456
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 457 H-EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEgsqgpegesqpwltddaDQQ 535
Cdd:PTZ00121 1596 EvMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA-----------------EEE 1658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 536 SPLQRDLEKPGEREDLVSAGQ-RDIPEDQRGEVEMAIEPVEqsgdwgahfggvdgvdvEGKEASQIDNPQPQERQKEGTP 614
Cdd:PTZ00121 1659 NKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEALKKEAE-----------------EAKKAEELKKKEAEEKKKAEEL 1721
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1958678989 615 AREEKEATAadidrKVEELRWQEVDERPRPYTFQVSSGSRQ 655
Cdd:PTZ00121 1722 KKAEEENKI-----KAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
157-486 |
1.49e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 157 AKHKLSVKPKNQRVSRKHRWLAQDRQNAPGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCK 236
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 237 KQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQSglEEQRGSEQELGEADDpT 316
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA--EEAKIKAEELKKAEE-E 1631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 317 RLEAEERRREQEKAERQAEKLRQREEAER--QEEELRQREEAERQAEELRQREEAERQEEELRQREAENQE--EKLRQRE 392
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKikAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKkaEELKKKE 1711
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 393 AEKQEEEVRQREVEgQEEELKQREAKRQEEELRqleeaERQEKLRQREAQKQEEEELRQREAERHEKLRQHEAERQEEEL 472
Cdd:PTZ00121 1712 AEEKKKAEELKKAE-EENKIKAEEAKKEAEEDK-----KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
|
330
....*....|....
gi 1958678989 473 RQRERQRAQEEEAK 486
Cdd:PTZ00121 1786 DEEDEKRRMEVDKK 1799
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
208-516 |
1.98e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.37 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 208 QGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAG 287
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 288 KAPPEEGPQS----GLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEEL-RQREEAERQAEE 362
Cdd:PTZ00121 1545 KKKADELKKAeelkKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEE 1624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 363 LRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEElkQREAKRQEEELRQLEEAERQEKLRQREAQ 442
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED--KKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 443 KQEE-EELRQREAERHEKLRQHEAERQ----------EEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEApep 511
Cdd:PTZ00121 1703 KAEElKKKEAEEKKKAEELKKAEEENKikaeeakkeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA--- 1779
|
....*
gi 1958678989 512 LVEEG 516
Cdd:PTZ00121 1780 VIEEE 1784
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
784-1159 |
2.48e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.01 E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 784 RGDREPARVGDEPAPRARCDSRGNVRKTPPVNAKFSIMPAwqkfsdSGAETFKQSTDGESvrkkpGPAPSEETTPTPQPL 863
Cdd:PHA03307 59 AAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA------SPAREGSPTPPGPS-----SPDPPPPTPPPASPP 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 864 PAGAPELQKNLEKQEVSQEPPDTTDGCKFAK--DLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDP--AMPGGE 939
Cdd:PHA03307 128 PSPAPDLSEMLRPVGSPGPPPAASPPAAGASpaAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPaaASPRPP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 940 EKASPFGIKLRRtnyslrfhcdqqaeqkkkkRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESH 1019
Cdd:PHA03307 208 RRSSPISASASS-------------------PAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTR 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1020 PSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTplsmqkpalAPKPASQTPPSSPLSKLSRPHIVELLTRRAGKL--DSE 1097
Cdd:PHA03307 269 IWEASGWNGPSSRPGPASSSSSPRERSPSPSPS---------SPGSGPAPSSPRASSSSSSSRESSSSSTSSSSEssRGA 339
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958678989 1098 PSEPAKENQESRDSQPPSPSLLEEPKGQKRdekdvlekkPASPPLPSSQQERPSLTPETGRK 1159
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRP---------RPSRAPSSPAASAGRPTRRRARA 392
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
898-1256 |
4.71e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 44.68 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 898 SFLVPSLPSpQKAASRTESTTSLDSETTSDVGSPDPAM---------PGGEEKASPFGIKLRRTNYSLRF-HCDQQAEQK 967
Cdd:PTZ00449 517 SGLPPKAPG-DKEGEEGEHEDSKESDEPKEGGKPGETKegevgkkpgPAKEHKPSKIPTLSKKPEFPKDPkHPKDPEEPK 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 968 KKKRHSSTGDSVdgdAPPGERNPEATFLKHGPSLPQE----RRPAlAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAP 1043
Cdd:PTZ00449 596 KPKRPRSAQRPT---RPKSPKLPELLDIPKSPKRPESpkspKRPP-PPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1044 EQD------KVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHIVELLTRRAGKLDSEPSEPAKENqesrDSQPPSPS 1117
Cdd:PTZ00449 672 KEKfyddylDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDP----DAEQPDDI 747
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1118 LLEEPKGQKRDEkdvLEKKPASPPLPSSQQE---RPSLTPETGRKEKPMLQ--------------------SRHSLDGSK 1174
Cdd:PTZ00449 748 EFFTPPEEERTF---FHETPADTPLPDILAEefkEEDIHAETGEPDEAMKRpdspsehedkppgdhpslpkKRHRLDGLA 824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1175 LTEKAETAQPLWIT-------LALQKQKGFREQQATREERKQAREAKQ------AEKLSKETASVSQQPGSSRV------ 1235
Cdd:PTZ00449 825 LSTTDLESDAGRIAkdasgkiVKLKRSKSFDDLTTVEEAEEMGAEARKivvdddGTEADDEDTHPPEEKHKSEVrrrrpp 904
|
410 420
....*....|....*....|.
gi 1958678989 1236 SKAGSVHKPAAPSEEKKPETA 1256
Cdd:PTZ00449 905 KKPSKPKKPSKPKKPKKPDSA 925
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
812-1255 |
1.81e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 812 PPVNAKFSIMPAWQKFSDSGAETFKQSTDGESVRKKPGPAPSEETTPTP--------QPLPAGA-----PELQKNLEKQE 878
Cdd:pfam03154 207 PPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpppsqvspQPLPQPSlhgqmPPMPHSLQTGP 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 879 VSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDPAMPGGEEKASPFGIKLRRTNYSLRF 958
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 959 HCDQQAEQKKKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAvHPGLPPASG 1038
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ-SQSLPPPAA 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1039 QTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHivelltrragkldSEPSEPAKENQESRDSQPPSPSL 1118
Cdd:pfam03154 446 SHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAM-------------PGIQPPSSASVSSSGPVPAAVSC 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1119 LEEPKGQKRDEKDVLEKKPASPPLPSSQQERPSL--TP----ETGRKEKPMLQSRHS----------LDGSKLTEKAETA 1182
Cdd:pfam03154 513 PLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVvnTPshasQSARFYKHLDRGYNScartdlyfmpLAGSKLAKKREEA 592
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958678989 1183 QPLWITLALQKQKGFREQQATRE-ERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHkpAAPSEEKKPET 1255
Cdd:pfam03154 593 LEKAKREAEQKAREEKEREKEKEkEREREREREREAERAAKASSSSHEGRMGDPQLAGPAH--MRPSFEPPPTT 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
218-532 |
2.41e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 218 HEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERrlweeslrqelLEEEEEEAEEVGLLLQAGKAPPEEGPQS 297
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-----------LELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 298 GLEEQRGSEQELGEADdptrleaEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELR 377
Cdd:COG1196 307 LEERRRELEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 378 QREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAERH 457
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958678989 458 EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDA 532
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
850-1101 |
4.65e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.46 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 850 PAPSEETTPTPQPLPAGAPElqknlekqeVSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDsettsdvg 929
Cdd:PHA03247 269 PETARGATGPPPPPEAAAPN---------GAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAEEEDDED-------- 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 930 spdpampGGEEKASPFGikLRRTNYSLRFhcdqqaeqKKKKRHSSTGDSVDGDAPPGERNPEATFL--KHGPSLPQERRP 1007
Cdd:PHA03247 332 -------GAMEVVSPLP--RPRQHYPLGF--------PKRRRPTWTPPSSLEDLSAGRHHPKRASLptRKRRSARHAATP 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678989 1008 ALAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTPLSMQKPALAPK---PASQTPPSSPLSKLSRPHIV 1084
Cdd:PHA03247 395 FARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPErqpPAPATEPAPDDPDDATRKAL 474
|
250
....*....|....*..
gi 1958678989 1085 ELLTRRagkldsEPSEP 1101
Cdd:PHA03247 475 DALRER------RPPEP 485
|
|
| |
