|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
51-179 |
1.77e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
:
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.77e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 51 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 130
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678973 131 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 179
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 super family |
cl33186 |
104 kDa microneme/rhoptry antigen; Provisional |
971-1315 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
The actual alignment was detected with superfamily member PTZ00449:
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 971 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1049
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1050 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1129
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1130 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1209
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1210 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1283
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678973 1284 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1315
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
193-640 |
1.98e-08 |
|
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 193 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 272
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 273 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 344
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 345 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 424
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 425 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 501
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 502 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 580
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 581 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 640
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
51-179 |
1.77e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.77e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 51 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 130
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678973 131 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 179
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
971-1315 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 971 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1049
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1050 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1129
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1130 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1209
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1210 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1283
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678973 1284 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1315
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
193-640 |
1.98e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 193 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 272
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 273 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 344
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 345 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 424
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 425 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 501
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 502 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 580
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 581 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 640
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
818-1261 |
1.86e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 818 PPVNAKFSIMPAWQKFSDSGAETFKQSTDGESVRKKPGPAPSEETTPTP--------QPLPAGA-----PELQKNLEKQE 884
Cdd:pfam03154 207 PPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpppsqvspQPLPQPSlhgqmPPMPHSLQTGP 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 885 VSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDPAMPGGEEKASPFGIKLRRTNYSLRF 964
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 965 HCDQQAEQKKKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAvHPGLPPASG 1044
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ-SQSLPPPAA 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1045 QTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHivelltrragkldSEPSEPAKENQESRDSQPPSPSL 1124
Cdd:pfam03154 446 SHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAM-------------PGIQPPSSASVSSSGPVPAAVSC 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1125 LEEPKGQKRDEKDVLEKKPASPPLPSSQQERPSL--TP----ETGRKEKPMLQSRHS----------LDGSKLTEKAETA 1188
Cdd:pfam03154 513 PLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVvnTPshasQSARFYKHLDRGYNScartdlyfmpLAGSKLAKKREEA 592
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958678973 1189 QPLWITLALQKQKGFREQQATRE-ERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHkpAAPSEEKKPET 1261
Cdd:pfam03154 593 LEKAKREAEQKAREEKEREKEKEkEREREREREREAERAAKASSSSHEGRMGDPQLAGPAH--MRPSFEPPPTT 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
224-538 |
2.32e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.62 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 224 HEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERrlweeslrqelLEEEEEEAEEVGLLLQAGKAPPEEGPQS 303
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-----------LELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 304 GLEEQRGSEQELGEADdptrleaEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELR 383
Cdd:COG1196 307 LEERRRELEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 384 QREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAERH 463
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958678973 464 EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDA 538
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4592 |
pfam15262 |
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ... |
51-179 |
1.77e-41 |
|
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.
Pssm-ID: 464602 [Multi-domain] Cd Length: 127 Bit Score: 148.72 E-value: 1.77e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 51 KNIKFGQRPSnVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSdTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKP 130
Cdd:pfam15262 1 QNIKLGQPPP-SIPTKRADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1958678973 131 SRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRK 179
Cdd:pfam15262 79 SRPKSPFSPSGTIEPINFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
971-1315 |
1.28e-08 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 59.70 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 971 EQKKKKRHSSTGDSVDGDAPPgeRNPEATFLKhgPSLPQERRPALAPRRDSAES-HPSGHCVAAAVHPGlppASGQTPAP 1049
Cdd:PTZ00449 491 KSKKKLAPIEEEDSDKHDEPP--EGPEASGLP--PKAPGDKEGEEGEHEDSKESdEPKEGGKPGETKEG---EVGKKPGP 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1050 EQDKVASKTPLSMQKPALAPKPASQTPPSSPLSklsrphivelltrragkldsePSEPAKENQESRDSQPPSPSLLEEPK 1129
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK---------------------PKRPRSAQRPTRPKSPKLPELLDIPK 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1130 GQKRDEKDVLEKKPASPPLPSSqQERPSlTPETGRKEKPMLQSRHSLDGSkltekaetaqplwitlalqkqkgFREQQAT 1209
Cdd:PTZ00449 623 SPKRPESPKSPKRPPPPQRPSS-PERPE-GPKIIKSPKPPKSPKPPFDPK-----------------------FKEKFYD 677
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1210 REERKQAR--EAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSN----TLPTSVT 1283
Cdd:PTZ00449 678 DYLDAAAKskETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDieffTPPEEER 757
|
330 340 350
....*....|....*....|....*....|..
gi 1958678973 1284 VEISDSAPSAPLVKEVTKRFSTPDAAPVSTEP 1315
Cdd:PTZ00449 758 TFFHETPADTPLPDILAEEFKEEDIHAETGEP 789
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
193-640 |
1.98e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 193 SFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLR 272
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKA 1166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 273 QELLEEEEEEAEEVGLLLQAGKAPPE---EGPQSGLEEQRGSE-----QELGEADDPTRLEAEERRREQEKAERQAEKLR 344
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEElrkAEDARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 345 QREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAK 424
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 425 RQEEELRQLEEAERQEK---LRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEA 501
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 502 KHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLV-SAGQRDIPEDQRGEVEMAIEPV 580
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkKAEEAKKADEAKKKAEEAKKAD 1486
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 581 EQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELR 640
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
854-1161 |
1.23e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.40 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 854 PGPAPSEETTPTPQPLP-AGAPELQKNLEKQEVSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTS 932
Cdd:PHA03247 2559 APPAAPDRSVPPPRPAPrPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 933 DVGSPDPAMPGGEEKASPFGIKLRRTNYSLRfhcdqqaeqkkKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERR 1012
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARR-----------LGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1013 PALAPRR-DSAESHPSGHCVAAAVHPGlPPASGQTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHIVE 1091
Cdd:PHA03247 2708 PEPAPHAlVSATPLPPGPAAARQASPA-LPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1092 LLTRRAGKLDSEPSEPAKenqesrdSQPPSPSLLEEPKgqkrdEKDVLEKKPASPPLPSSQQERPSLTPE 1161
Cdd:PHA03247 2787 AVASLSESRESLPSPWDP-------ADPPAAVLAPAAA-----LPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
154-647 |
1.66e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 154 AIARLDNSAAKHKLSVKPKNQRVSRKHRWLAQDRQNAPGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDY 233
Cdd:PTZ00121 1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 234 WRELEAKCK----KQKAEAAeKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQSglEEQR 309
Cdd:PTZ00121 1308 KKKAEEAKKadeaKKKAEEA-KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA--DAAK 1384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 310 GSEQELGEADDPTRLEAEERRREQEKAERQAEKlrqreeaerqeeelRQREEAERQAEELRQREEAERQEEELRQREaen 389
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAK--------------KKADEAKKKAEEKKKADEAKKKAEEAKKAD--- 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 390 qEEKLRQREAEKQEEEVRQREVEGQEEELKQR--EAKRQEEELRQLEEAERQ--EKLRQREAQKQEEEELRQREAERHEK 465
Cdd:PTZ00121 1448 -EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKaeEAKKADEAKKKAEEAKKKadEAKKAAEAKKKADEAKKAEEAKKADE 1526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 466 LRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLV---EEGSQGPEGESQPWLTDDADQQS 542
Cdd:PTZ00121 1527 AKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaEEAKKAEEARIEEVMKLYEEEKK 1606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 543 PLQRDLEKpgEREDLVSAGQRDIPEDQRGEVEMAIEPVEQsgdwgahfggvdgvdvEGKEASQIdnpqpqERQKEGTPAR 622
Cdd:PTZ00121 1607 MKAEEAKK--AEEAKIKAEELKKAEEEKKKVEQLKKKEAE----------------EKKKAEEL------KKAEEENKIK 1662
|
490 500
....*....|....*....|....*.
gi 1958678973 623 EEKEATAADID-RKVEELRWQEVDER 647
Cdd:PTZ00121 1663 AAEEAKKAEEDkKKAEEAKKAEEDEK 1688
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
208-646 |
7.24e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 7.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 208 EDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVG 287
Cdd:PTZ00121 1150 DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV 1229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 288 LLLQAGKAPPEEGPQSglEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAE 367
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKA--EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 368 ELRQREEAERQEEELRQREAENQEEKLRQR-EAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQRE 446
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKKKaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 447 AQKQEEEELRQREAERHEKL----RQHEAERQEEELRQRERQRAQEEEAKRmlqEEEEAKHIEELKGR--EKEAPEPLVE 520
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDKKKAdelkKAAAAKKKADEAKKKAEEKKKADEAKK---KAEEAKKADEAKKKaeEAKKAEEAKK 1464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 521 EGSQGPEGESQPWLTDDADQQSPLQRDLEKPGER-EDLVSAGQRDIPEDQRGEVEMAIEPVEQSgdwgahfggvdgvdvE 599
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAK---------------K 1529
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1958678973 600 GKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELRWQEVDE 646
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
223-661 |
9.48e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 9.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 223 SHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRlweeSLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQ 302
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK----KKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 303 SGLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKlrQREEAERQEEELRQREEAERQAEELRQREEAERQEEEL 382
Cdd:PTZ00121 1438 KKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKK--KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 383 RQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAER 462
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 463 H-EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEgsqgpegesqpwltddaDQQ 541
Cdd:PTZ00121 1596 EvMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA-----------------EEE 1658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 542 SPLQRDLEKPGEREDLVSAGQ-RDIPEDQRGEVEMAIEPVEqsgdwgahfggvdgvdvEGKEASQIDNPQPQERQKEGTP 620
Cdd:PTZ00121 1659 NKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEALKKEAE-----------------EAKKAEELKKKEAEEKKKAEEL 1721
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1958678973 621 AREEKEATAadidrKVEELRWQEVDERPRPYTFQVSSGSRQ 661
Cdd:PTZ00121 1722 KKAEEENKI-----KAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
163-492 |
1.18e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 163 AKHKLSVKPKNQRVSRKHRWLAQDRQNAPGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCK 242
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 243 KQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQSglEEQRGSEQELGEADDpT 322
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA--EEAKIKAEELKKAEE-E 1631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 323 RLEAEERRREQEKAERQAEKLRQREEAER--QEEELRQREEAERQAEELRQREEAERQEEELRQREAENQE--EKLRQRE 398
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKikAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKkaEELKKKE 1711
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 399 AEKQEEEVRQREVEgQEEELKQREAKRQEEELRqleeaERQEKLRQREAQKQEEEELRQREAERHEKLRQHEAERQEEEL 478
Cdd:PTZ00121 1712 AEEKKKAEELKKAE-EENKIKAEEAKKEAEEDK-----KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
|
330
....*....|....
gi 1958678973 479 RQRERQRAQEEEAK 492
Cdd:PTZ00121 1786 DEEDEKRRMEVDKK 1799
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
214-522 |
1.64e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 214 QGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAG 293
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 294 KAPPEEGPQS----GLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEEL-RQREEAERQAEE 368
Cdd:PTZ00121 1545 KKKADELKKAeelkKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEE 1624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 369 LRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEElkQREAKRQEEELRQLEEAERQEKLRQREAQ 448
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED--KKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 449 KQEE-EELRQREAERHEKLRQHEAERQ----------EEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEApep 517
Cdd:PTZ00121 1703 KAEElKKKEAEEKKKAEELKKAEEENKikaeeakkeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA--- 1779
|
....*
gi 1958678973 518 LVEEG 522
Cdd:PTZ00121 1780 VIEEE 1784
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
790-1165 |
3.00e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 48.63 E-value: 3.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 790 RGDREPARVGDEPAPRARCDSRGNVRKTPPVNAKFSIMPAwqkfsdSGAETFKQSTDGESvrkkpGPAPSEETTPTPQPL 869
Cdd:PHA03307 59 AAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA------SPAREGSPTPPGPS-----SPDPPPPTPPPASPP 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 870 PAGAPELQKNLEKQEVSQEPPDTTDGCKFAK--DLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDP--AMPGGE 945
Cdd:PHA03307 128 PSPAPDLSEMLRPVGSPGPPPAASPPAAGASpaAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPaaASPRPP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 946 EKASPFGIKLRRtnyslrfhcdqqaeqkkkkRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESH 1025
Cdd:PHA03307 208 RRSSPISASASS-------------------PAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTR 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1026 PSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTplsmqkpalAPKPASQTPPSSPLSKLSRPHIVELLTRRAGKL--DSE 1103
Cdd:PHA03307 269 IWEASGWNGPSSRPGPASSSSSPRERSPSPSPS---------SPGSGPAPSSPRASSSSSSSRESSSSSTSSSSEssRGA 339
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958678973 1104 PSEPAKENQESRDSQPPSPSLLEEPKGQKRdekdvlekkPASPPLPSSQQERPSLTPETGRK 1165
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRP---------RPSRAPSSPAASAGRPTRRRARA 392
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
904-1262 |
4.69e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 44.68 E-value: 4.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 904 SFLVPSLPSpQKAASRTESTTSLDSETTSDVGSPDPAM---------PGGEEKASPFGIKLRRTNYSLRF-HCDQQAEQK 973
Cdd:PTZ00449 517 SGLPPKAPG-DKEGEEGEHEDSKESDEPKEGGKPGETKegevgkkpgPAKEHKPSKIPTLSKKPEFPKDPkHPKDPEEPK 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 974 KKKRHSSTGDSVdgdAPPGERNPEATFLKHGPSLPQE----RRPAlAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAP 1049
Cdd:PTZ00449 596 KPKRPRSAQRPT---RPKSPKLPELLDIPKSPKRPESpkspKRPP-PPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1050 EQD------KVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHIVELLTRRAGKLDSEPSEPAKENqesrDSQPPSPS 1123
Cdd:PTZ00449 672 KEKfyddylDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDP----DAEQPDDI 747
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1124 LLEEPKGQKRDEkdvLEKKPASPPLPSSQQE---RPSLTPETGRKEKPMLQ--------------------SRHSLDGSK 1180
Cdd:PTZ00449 748 EFFTPPEEERTF---FHETPADTPLPDILAEefkEEDIHAETGEPDEAMKRpdspsehedkppgdhpslpkKRHRLDGLA 824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1181 LTEKAETAQPLWIT-------LALQKQKGFREQQATREERKQAREAKQ------AEKLSKETASVSQQPGSSRV------ 1241
Cdd:PTZ00449 825 LSTTDLESDAGRIAkdasgkiVKLKRSKSFDDLTTVEEAEEMGAEARKivvdddGTEADDEDTHPPEEKHKSEVrrrrpp 904
|
410 420
....*....|....*....|.
gi 1958678973 1242 SKAGSVHKPAAPSEEKKPETA 1262
Cdd:PTZ00449 905 KKPSKPKKPSKPKKPKKPDSA 925
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
818-1261 |
1.86e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 818 PPVNAKFSIMPAWQKFSDSGAETFKQSTDGESVRKKPGPAPSEETTPTP--------QPLPAGA-----PELQKNLEKQE 884
Cdd:pfam03154 207 PPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPpppsqvspQPLPQPSlhgqmPPMPHSLQTGP 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 885 VSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDPAMPGGEEKASPFGIKLRRTNYSLRF 964
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 965 HCDQQAEQKKKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAvHPGLPPASG 1044
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ-SQSLPPPAA 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1045 QTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHivelltrragkldSEPSEPAKENQESRDSQPPSPSL 1124
Cdd:pfam03154 446 SHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAM-------------PGIQPPSSASVSSSGPVPAAVSC 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1125 LEEPKGQKRDEKDVLEKKPASPPLPSSQQERPSL--TP----ETGRKEKPMLQSRHS----------LDGSKLTEKAETA 1188
Cdd:pfam03154 513 PLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVvnTPshasQSARFYKHLDRGYNScartdlyfmpLAGSKLAKKREEA 592
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958678973 1189 QPLWITLALQKQKGFREQQATRE-ERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHkpAAPSEEKKPET 1261
Cdd:pfam03154 593 LEKAKREAEQKAREEKEREKEKEkEREREREREREAERAAKASSSSHEGRMGDPQLAGPAH--MRPSFEPPPTT 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
224-538 |
2.32e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.62 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 224 HEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERrlweeslrqelLEEEEEEAEEVGLLLQAGKAPPEEGPQS 303
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-----------LELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 304 GLEEQRGSEQELGEADdptrleaEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELR 383
Cdd:COG1196 307 LEERRRELEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 384 QREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAERH 463
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958678973 464 EKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDA 538
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
856-1107 |
5.30e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.46 E-value: 5.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 856 PAPSEETTPTPQPLPAGAPElqknlekqeVSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDsettsdvg 935
Cdd:PHA03247 269 PETARGATGPPPPPEAAAPN---------GAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAEEEDDED-------- 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 936 spdpampGGEEKASPFGikLRRTNYSLRFhcdqqaeqKKKKRHSSTGDSVDGDAPPGERNPEATFL--KHGPSLPQERRP 1013
Cdd:PHA03247 332 -------GAMEVVSPLP--RPRQHYPLGF--------PKRRRPTWTPPSSLEDLSAGRHHPKRASLptRKRRSARHAATP 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958678973 1014 ALAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTPLSMQKPALAPK---PASQTPPSSPLSKLSRPHIV 1090
Cdd:PHA03247 395 FARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPErqpPAPATEPAPDDPDDATRKAL 474
|
250
....*....|....*..
gi 1958678973 1091 ELLTRRagkldsEPSEP 1107
Cdd:PHA03247 475 DALRER------RPPEP 485
|
|
| |
