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Conserved domains on  [gi|1958676936|ref|XP_038948233|]
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zona pellucida-binding protein 1 isoform X8 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sp38 super family cl20050
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 102-230 9.88e-62

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


The actual alignment was detected with superfamily member pfam07354:

Pssm-ID: 336682  Cd Length: 177  Bit Score: 192.78  E-value: 9.88e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958676936 102 YHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCE-- 179
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEdt 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958676936 180 ASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPG 230
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQFETLPEIHYVEGSLQVVWIDRCRPG 131
 
Name Accession Description Interval E-value
Sp38 pfam07354
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 102-230 9.88e-62

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


Pssm-ID: 336682  Cd Length: 177  Bit Score: 192.78  E-value: 9.88e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958676936 102 YHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCE-- 179
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEdt 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958676936 180 ASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPG 230
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQFETLPEIHYVEGSLQVVWIDRCRPG 131
 
Name Accession Description Interval E-value
Sp38 pfam07354
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 102-230 9.88e-62

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


Pssm-ID: 336682  Cd Length: 177  Bit Score: 192.78  E-value: 9.88e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958676936 102 YHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCE-- 179
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEdt 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958676936 180 ASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPG 230
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQFETLPEIHYVEGSLQVVWIDRCRPG 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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