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Conserved domains on  [gi|1958669637|ref|XP_038945707|]
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coiled-coil domain-containing protein 62 isoform X7 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
3-136 4.27e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 4.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637   3 KLKDKDIIEAVNHISDCSGKFKLLEHALRDAKMAETCVVKEKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRL 82
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958669637  83 KQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQNLRQIYVKQQSDLQ 136
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
3-136 4.27e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 4.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637   3 KLKDKDIIEAVNHISDCSGKFKLLEHALRDAKMAETCVVKEKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRL 82
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958669637  83 KQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQNLRQIYVKQQSDLQ 136
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
PRK12704 PRK12704
phosphodiesterase; Provisional
42-162 1.41e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637  42 KEKQDYKQ-KLKALRIEVNKLREDLnEKttENNEQREEIIRLKQeksclhdeliftveREKRKDELLDIAKSKQDRTNSE 120
Cdd:PRK12704   49 KEAEAIKKeALLEAKEEIHKLRNEF-EK--ELRERRNELQKLEK--------------RLLQKEENLDRKLELLEKREEE 111
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958669637 121 LQNLRQIYVKQQSDLQFLNFNVENS-----QELIQIHGLKMEEPKAL 162
Cdd:PRK12704  112 LEKKEKELEQKQQELEKKEEELEELieeqlQELERISGLTAEEAKEI 158
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
43-150 5.53e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637   43 EKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRLKQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQ 122
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340
                           90       100
                   ....*....|....*....|....*...
gi 1958669637  123 NLRQIYVKQQSDLQFLNFNVENSQELIQ 150
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELE 368
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
3-136 4.27e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 4.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637   3 KLKDKDIIEAVNHISDCSGKFKLLEHALRDAKMAETCVVKEKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRL 82
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958669637  83 KQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQNLRQIYVKQQSDLQ 136
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
PRK12704 PRK12704
phosphodiesterase; Provisional
42-162 1.41e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637  42 KEKQDYKQ-KLKALRIEVNKLREDLnEKttENNEQREEIIRLKQeksclhdeliftveREKRKDELLDIAKSKQDRTNSE 120
Cdd:PRK12704   49 KEAEAIKKeALLEAKEEIHKLRNEF-EK--ELRERRNELQKLEK--------------RLLQKEENLDRKLELLEKREEE 111
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958669637 121 LQNLRQIYVKQQSDLQFLNFNVENS-----QELIQIHGLKMEEPKAL 162
Cdd:PRK12704  112 LEKKEKELEQKQQELEKKEEELEELieeqlQELERISGLTAEEAKEI 158
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
42-124 4.12e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.43  E-value: 4.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637  42 KEKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRLKQEKSCLHDELIfTVER--EKRKDELLDIAKS--KQDRT 117
Cdd:COG3883    23 KELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIA-EAEAeiEERREELGERARAlyRSGGS 101

                  ....*..
gi 1958669637 118 NSELQNL 124
Cdd:COG3883   102 VSYLDVL 108
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
43-150 5.53e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669637   43 EKQDYKQKLKALRIEVNKLREDLNEKTTENNEQREEIIRLKQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQ 122
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340
                           90       100
                   ....*....|....*....|....*...
gi 1958669637  123 NLRQIYVKQQSDLQFLNFNVENSQELIQ 150
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELE 368
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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