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Conserved domains on  [gi|1958669056|ref|XP_038945493|]
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SUN domain-containing protein 1 isoform X12 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sad1_UNC pfam07738
Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that ...
 741-875 1.64e-56

Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that is involved in nuclear anchoring and migration during development. The S. pombe Sad1 protein localizes at the spindle pole body. UNC-84 and and Sad1 share a common C-terminal region, that is often termed the SUN (Sad1 and UNC) domain. In mammals, the SUN domain is present in two proteins, Sun1 and Sun2. The SUN domain of Sun2 has been demonstrated to be in the periplasm.


:

Pssm-ID: 400199  Cd Length: 130  Bit Score: 190.19  E-value: 1.64e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 741 LWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLsptgnISSAPRDFAVYGLETEYQEEGQ 820
Cdd:pfam07738   1 LNYEAKPPKVILQPDYMPGPCWSFKGSRGFVVIELSEFIIVEAITLEHVEKSV-----FSSAPKDFEVSGSDRYPTTKWV 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958669056 821 PLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEP 875
Cdd:pfam07738  76 LLGEFSYDLDGKTIQTFQLENPPDIWVKYVKLRILSNYGNEHYTCLYRFRVHGTV 130
MRP super family cl09637
Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins ...
 93-380 2.04e-51

Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins that form a heteromeric complex. The MRP1/MRP2 heterotetrameric complex binds to guide RNAs and stabilizes them in an unfolded conformation suitable for RNA-RNA hybridization. Each MRP subunit adopts a 'whirly' transcription factor fold.


The actual alignment was detected with superfamily member pfam09387:

Pssm-ID: 430576  Cd Length: 192  Bit Score: 178.60  E-value: 2.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056  93 AYSSGDGQTVDTHISTSRATPAKGRETRTVKQ-RSASKPAFSINHLSGKGLSSStshdsscslrsatvlrhpvldeSLIR 171
Cdd:pfam09387   1 SSAFADGSALDAMNQNRRAQSWRDRAARTQKQrRSASPPAFDIVHWSRKDISSG----------------------SLIR 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 172 eQTKVDHFWGLD----DDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARtdaLTAHSAVHGPTSRVYSRDRTl 247
Cdd:pfam09387  59 -QTKVDHFWGLDyhlpDDGDLKGGPKAAPQGNGDRAVSVALPNGYTARFCSVLEGR---LTKHEVASGPTNRVFSRDRA- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 248 rpphlghcgrmtagelsrvdgeslcddcKGKKHLETHTTTHSQLSQPHRAAGamgrlctytgdllvralrrtraagwsva 327
Cdd:pfam09387 134 ----------------------------QKNTYTLKCTSTKPAQGQSQRSNA---------------------------- 157

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958669056 328 eamwsvlwlavtapGKAASGTFWWLgsgwYQFVTLISWLNVFLLTRCLRNICK 380
Cdd:pfam09387 158 --------------GKAASEVFEWL----VQFVTLESWLNVFFLTRALRNICG 192
SUN1_cc1 cd21439
coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN ...
 518-569 1.23e-22

coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN domain-containing protein 1 (SUN1), also called protein unc-84 homolog A, or Sad1/unc-84 protein-like 1, is a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex which is involved in the connection between the nuclear lamina and the cytoskeleton. Besides the core SUN domain, SUN1 contains two coiled-coil domains (CC1 and CC2), which act as the intrinsic dynamic regulators for controlling the activity of the SUN domain. This model corresponds to CC1 that may function as an activation segment to release CC2-mediated inhibition of the SUN domain.


:

Pssm-ID: 410605 [Multi-domain]  Cd Length: 55  Bit Score: 91.57  E-value: 1.23e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958669056 518 PDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQ 569
Cdd:cd21439     2 PLSQTDFMAFHQEHELRISNLEDLLGKLSEKSEAIQKELEQTKLRTASGADE 53
CALCOCO1 super family cl37761
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 470-632 3.64e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


The actual alignment was detected with superfamily member pfam07888:

Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.20  E-value: 3.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 470 DERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMvgqhlqEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKS 549
Cdd:pfam07888  72 ERQRRELESRVAELKEELRQSREKHEELEEKYKEL------SASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRV 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 550 EAIQKELEETKLRAGRDEEQPLLDRVQHLELELNLLKSQL------SDWQHLRSSCEQADA---RIQETV----QLMFSE 616
Cdd:pfam07888 146 LERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEelrslsKEFQELRNSLAQRDTqvlQLQDTIttltQKLTTA 225

                         170
                  ....*....|....*.
gi 1958669056 617 DQPGGSLEWLLQKLSS 632
Cdd:pfam07888 226 HRKEAENEALLEELRS 241
 
Name Accession Description Interval E-value
Sad1_UNC pfam07738
Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that ...
 741-875 1.64e-56

Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that is involved in nuclear anchoring and migration during development. The S. pombe Sad1 protein localizes at the spindle pole body. UNC-84 and and Sad1 share a common C-terminal region, that is often termed the SUN (Sad1 and UNC) domain. In mammals, the SUN domain is present in two proteins, Sun1 and Sun2. The SUN domain of Sun2 has been demonstrated to be in the periplasm.


Pssm-ID: 400199  Cd Length: 130  Bit Score: 190.19  E-value: 1.64e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 741 LWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLsptgnISSAPRDFAVYGLETEYQEEGQ 820
Cdd:pfam07738   1 LNYEAKPPKVILQPDYMPGPCWSFKGSRGFVVIELSEFIIVEAITLEHVEKSV-----FSSAPKDFEVSGSDRYPTTKWV 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958669056 821 PLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEP 875
Cdd:pfam07738  76 LLGEFSYDLDGKTIQTFQLENPPDIWVKYVKLRILSNYGNEHYTCLYRFRVHGTV 130
MRP pfam09387
Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins ...
 93-380 2.04e-51

Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins that form a heteromeric complex. The MRP1/MRP2 heterotetrameric complex binds to guide RNAs and stabilizes them in an unfolded conformation suitable for RNA-RNA hybridization. Each MRP subunit adopts a 'whirly' transcription factor fold.


Pssm-ID: 430576  Cd Length: 192  Bit Score: 178.60  E-value: 2.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056  93 AYSSGDGQTVDTHISTSRATPAKGRETRTVKQ-RSASKPAFSINHLSGKGLSSStshdsscslrsatvlrhpvldeSLIR 171
Cdd:pfam09387   1 SSAFADGSALDAMNQNRRAQSWRDRAARTQKQrRSASPPAFDIVHWSRKDISSG----------------------SLIR 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 172 eQTKVDHFWGLD----DDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARtdaLTAHSAVHGPTSRVYSRDRTl 247
Cdd:pfam09387  59 -QTKVDHFWGLDyhlpDDGDLKGGPKAAPQGNGDRAVSVALPNGYTARFCSVLEGR---LTKHEVASGPTNRVFSRDRA- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 248 rpphlghcgrmtagelsrvdgeslcddcKGKKHLETHTTTHSQLSQPHRAAGamgrlctytgdllvralrrtraagwsva 327
Cdd:pfam09387 134 ----------------------------QKNTYTLKCTSTKPAQGQSQRSNA---------------------------- 157

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958669056 328 eamwsvlwlavtapGKAASGTFWWLgsgwYQFVTLISWLNVFLLTRCLRNICK 380
Cdd:pfam09387 158 --------------GKAASEVFEWL----VQFVTLESWLNVFFLTRALRNICG 192
SUN1_cc1 cd21439
coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN ...
 518-569 1.23e-22

coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN domain-containing protein 1 (SUN1), also called protein unc-84 homolog A, or Sad1/unc-84 protein-like 1, is a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex which is involved in the connection between the nuclear lamina and the cytoskeleton. Besides the core SUN domain, SUN1 contains two coiled-coil domains (CC1 and CC2), which act as the intrinsic dynamic regulators for controlling the activity of the SUN domain. This model corresponds to CC1 that may function as an activation segment to release CC2-mediated inhibition of the SUN domain.


Pssm-ID: 410605 [Multi-domain]  Cd Length: 55  Bit Score: 91.57  E-value: 1.23e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958669056 518 PDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQ 569
Cdd:cd21439     2 PLSQTDFMAFHQEHELRISNLEDLLGKLSEKSEAIQKELEQTKLRTASGADE 53
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 470-632 3.64e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.20  E-value: 3.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 470 DERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMvgqhlqEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKS 549
Cdd:pfam07888  72 ERQRRELESRVAELKEELRQSREKHEELEEKYKEL------SASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRV 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 550 EAIQKELEETKLRAGRDEEQPLLDRVQHLELELNLLKSQL------SDWQHLRSSCEQADA---RIQETV----QLMFSE 616
Cdd:pfam07888 146 LERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEelrslsKEFQELRNSLAQRDTqvlQLQDTIttltQKLTTA 225

                         170
                  ....*....|....*.
gi 1958669056 617 DQPGGSLEWLLQKLSS 632
Cdd:pfam07888 226 HRKEAENEALLEELRS 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
470-618 5.10e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 5.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 470 DERLAELTVLLQKLQIRVDQVDDGREGLSLWVKdmvGQHLQEigSIEPPDAKTDFLTLHHDHEVRL-SSLEDVLRKLTEK 548
Cdd:COG4717   101 EEELEELEAELEELREELEKLEKLLQLLPLYQE---LEALEA--ELAELPERLEELEERLEELRELeEELEELEAELAEL 175

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 549 SEAIQKELEETKLRAgRDEEQPLLDRVQHLELELNLLKSQLsdwQHLRSSCEQADARIQETVQLMFSEDQ 618
Cdd:COG4717   176 QEELEELLEQLSLAT-EEELQDLAEELEELQQRLAELEEEL---EEAQEELEELEEELEQLENELEAAAL 241
 
Name Accession Description Interval E-value
Sad1_UNC pfam07738
Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that ...
 741-875 1.64e-56

Sad1 / UNC-like C-terminal; The C. elegans UNC-84 protein is a nuclear envelope protein that is involved in nuclear anchoring and migration during development. The S. pombe Sad1 protein localizes at the spindle pole body. UNC-84 and and Sad1 share a common C-terminal region, that is often termed the SUN (Sad1 and UNC) domain. In mammals, the SUN domain is present in two proteins, Sun1 and Sun2. The SUN domain of Sun2 has been demonstrated to be in the periplasm.


Pssm-ID: 400199  Cd Length: 130  Bit Score: 190.19  E-value: 1.64e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 741 LWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLsptgnISSAPRDFAVYGLETEYQEEGQ 820
Cdd:pfam07738   1 LNYEAKPPKVILQPDYMPGPCWSFKGSRGFVVIELSEFIIVEAITLEHVEKSV-----FSSAPKDFEVSGSDRYPTTKWV 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958669056 821 PLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEP 875
Cdd:pfam07738  76 LLGEFSYDLDGKTIQTFQLENPPDIWVKYVKLRILSNYGNEHYTCLYRFRVHGTV 130
MRP pfam09387
Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins ...
 93-380 2.04e-51

Mitochondrial RNA binding protein MRP; MRP1 and MRP2 are mitochondrial RNA binding proteins that form a heteromeric complex. The MRP1/MRP2 heterotetrameric complex binds to guide RNAs and stabilizes them in an unfolded conformation suitable for RNA-RNA hybridization. Each MRP subunit adopts a 'whirly' transcription factor fold.


Pssm-ID: 430576  Cd Length: 192  Bit Score: 178.60  E-value: 2.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056  93 AYSSGDGQTVDTHISTSRATPAKGRETRTVKQ-RSASKPAFSINHLSGKGLSSStshdsscslrsatvlrhpvldeSLIR 171
Cdd:pfam09387   1 SSAFADGSALDAMNQNRRAQSWRDRAARTQKQrRSASPPAFDIVHWSRKDISSG----------------------SLIR 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 172 eQTKVDHFWGLD----DDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARtdaLTAHSAVHGPTSRVYSRDRTl 247
Cdd:pfam09387  59 -QTKVDHFWGLDyhlpDDGDLKGGPKAAPQGNGDRAVSVALPNGYTARFCSVLEGR---LTKHEVASGPTNRVFSRDRA- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 248 rpphlghcgrmtagelsrvdgeslcddcKGKKHLETHTTTHSQLSQPHRAAGamgrlctytgdllvralrrtraagwsva 327
Cdd:pfam09387 134 ----------------------------QKNTYTLKCTSTKPAQGQSQRSNA---------------------------- 157

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958669056 328 eamwsvlwlavtapGKAASGTFWWLgsgwYQFVTLISWLNVFLLTRCLRNICK 380
Cdd:pfam09387 158 --------------GKAASEVFEWL----VQFVTLESWLNVFFLTRALRNICG 192
SUN1_cc1 cd21439
coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN ...
 518-569 1.23e-22

coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins; SUN domain-containing protein 1 (SUN1), also called protein unc-84 homolog A, or Sad1/unc-84 protein-like 1, is a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex which is involved in the connection between the nuclear lamina and the cytoskeleton. Besides the core SUN domain, SUN1 contains two coiled-coil domains (CC1 and CC2), which act as the intrinsic dynamic regulators for controlling the activity of the SUN domain. This model corresponds to CC1 that may function as an activation segment to release CC2-mediated inhibition of the SUN domain.


Pssm-ID: 410605 [Multi-domain]  Cd Length: 55  Bit Score: 91.57  E-value: 1.23e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958669056 518 PDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQ 569
Cdd:cd21439     2 PLSQTDFMAFHQEHELRISNLEDLLGKLSEKSEAIQKELEQTKLRTASGADE 53
SUN_cc1 cd21435
coiled-coil domain 1 of SUN domain-containing proteins; SUN (Sad1 and UNC-84) proteins (SUN1 ...
 521-560 5.44e-10

coiled-coil domain 1 of SUN domain-containing proteins; SUN (Sad1 and UNC-84) proteins (SUN1 and SUN2) are components of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex which is involved in the connection between the nuclear lamina and the cytoskeleton. Besides the core SUN domain, SUN proteins contain two coiled-coil domains (CC1 and CC2), which act as intrinsic dynamic regulators controlling the activity of the SUN domain. The model corresponds to CC1 that functions as an activation segment to release CC2-mediated inhibition of the SUN domain.


Pssm-ID: 410603 [Multi-domain]  Cd Length: 55  Bit Score: 55.88  E-value: 5.44e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958669056 521 KTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETK 560
Cdd:cd21435     5 QESSVKELGRLEAQLASLRQELAALTLKQEAIQKELEQTK 44
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 470-632 3.64e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.20  E-value: 3.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 470 DERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMvgqhlqEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKS 549
Cdd:pfam07888  72 ERQRRELESRVAELKEELRQSREKHEELEEKYKEL------SASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRV 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 550 EAIQKELEETKLRAGRDEEQPLLDRVQHLELELNLLKSQL------SDWQHLRSSCEQADA---RIQETV----QLMFSE 616
Cdd:pfam07888 146 LERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEelrslsKEFQELRNSLAQRDTqvlQLQDTIttltQKLTTA 225

                         170
                  ....*....|....*.
gi 1958669056 617 DQPGGSLEWLLQKLSS 632
Cdd:pfam07888 226 HRKEAENEALLEELRS 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
470-618 5.10e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 5.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 470 DERLAELTVLLQKLQIRVDQVDDGREGLSLWVKdmvGQHLQEigSIEPPDAKTDFLTLHHDHEVRL-SSLEDVLRKLTEK 548
Cdd:COG4717   101 EEELEELEAELEELREELEKLEKLLQLLPLYQE---LEALEA--ELAELPERLEELEERLEELRELeEELEELEAELAEL 175

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 549 SEAIQKELEETKLRAgRDEEQPLLDRVQHLELELNLLKSQLsdwQHLRSSCEQADARIQETVQLMFSEDQ 618
Cdd:COG4717   176 QEELEELLEQLSLAT-EEELQDLAEELEELQQRLAELEEEL---EEAQEELEELEEELEQLENELEAAAL 241
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
457-608 1.90e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056  457 QKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLS-----LWVKDMVGQHLQEIGSIEppDAKTDFLTLHHDh 531
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeySWDEIDVASAEREIAELE--AELERLDASSDD- 686

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958669056  532 evrLSSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQ--PLLDRVQHLELELNLLKSQLSDWQHlrsscEQADARIQE 608
Cdd:COG4913    687 ---LAALEEQLEELEAELEELEEELDELKGEIGRLEKEleQAEEELDELQDRLEAAEDLARLELR-----ALLEERFAA 757
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 457-611 5.23e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 5.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958669056 457 QKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLT-LHHDHEVRL 535
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEeRRRELEERL 318

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958669056 536 SSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQ--PLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQ 611
Cdd:COG1196   319 EELEEELAELEEELEELEEELEELEEELEEAEEEleEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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