NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958668749|ref|XP_038945394|]
View 

anaphase-promoting complex subunit 7 isoform X2 [Rattus norvegicus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1000094)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-463 3.64e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 3.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 396 ALLRNALANQSDCV-LHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKM-EKEGSPTDATQE 463
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELyEKLGDPEEALEL 234
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
179-303 1.04e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


:

Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 179 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 258
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1958668749 259 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.07e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749  32 PSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1958668749 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-463 3.64e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 3.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 396 ALLRNALANQSDCV-LHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKM-EKEGSPTDATQE 463
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELyEKLGDPEEALEL 234
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 141-442 5.55e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.02  E-value: 5.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 141 AYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL 220
Cdd:TIGR02917 438 ILSYLRSGQFDKALAAAKKLEKKQ--PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNP 515

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 221 EDVENLGCRLFNISDQHAEpwVVSGCHSFYSK--RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 298
Cdd:TIGR02917 516 DDAIQRFEKVLTIDPKNLR--AILALAGLYLRtgNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEA 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 299 IRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTqEKAKTLLDKALAQRPDYVKAV 378
Cdd:TIGR02917 594 ADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNY-AKAITSLKRALELKPDNTEAQ 672

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958668749 379 VKKAELLSREQKYEDGIALLRN-ALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQ 442
Cdd:TIGR02917 673 IGLAQLLLAAKRTESAKKIAKSlQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ 737
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
179-303 1.04e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 179 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 258
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1958668749 259 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.07e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749  32 PSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1958668749 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 272-303 1.01e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.01e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1958668749  272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 272-303 1.44e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.35  E-value: 1.44e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1958668749 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-463 3.64e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 3.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 317
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 318 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGI 395
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 396 ALLRNALANQSDCV-LHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKM-EKEGSPTDATQE 463
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELyEKLGDPEEALEL 234
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 252-462 4.36e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.09  E-value: 4.36e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 252 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANN 331
Cdd:COG2956    56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 332 VYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALA-NQSDC 408
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEqgDY---DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEqDPDYL 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958668749 409 VLHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEGSPTDATQ 462
Cdd:COG2956   213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALA 266
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 253-443 7.88e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 83.50  E-value: 7.88e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 253 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMvmannv 332
Cdd:COG3914    59 LLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL------ 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 333 yktlganaqtltllatvcledpvtqekakTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LH 411
Cdd:COG3914   133 -----------------------------AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAeAL 183

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1958668749 412 RILGDFLVSVNEYQEAMDQYSIALSLDPNDQK 443
Cdd:COG3914   184 NNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
265-441 1.29e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.28  E-value: 1.29e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 265 IQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLT 344
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 345 LLATVC--LEDPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVSV 421
Cdd:COG0457    81 NLGLALqaLGRY---EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAdALYNLGIALEKL 157

                         170       180
                  ....*....|....*....|
gi 1958668749 422 NEYQEAMDQYSIALSLDPND 441
Cdd:COG0457   158 GRYEEALELLEKLEAAALAA 177
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 176-438 5.45e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.23  E-value: 5.45e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 255
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 256 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 335
Cdd:COG2956    94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 336 LGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI 413
Cdd:COG2956   174 DPDCARALLLLAELYLEqgDY---EEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA 250

                         250       260
                  ....*....|....*....|....*
gi 1958668749 414 LGDFLVSVNEYQEAMDQYSIALSLD 438
Cdd:COG2956   251 LADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 141-405 3.02e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 3.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 141 AYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL 220
Cdd:COG2956    49 GNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 221 EDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIR 300
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 301 LAPCRLDCYEGLIECYLASNSireamvmannvyktlganaqtltllatvcledpvtQEKAKTLLDKALAQRPDyVKAVVK 380
Cdd:COG2956   207 QDPDYLPALPRLAELYEKLGD-----------------------------------PEEALELLRKALELDPS-DDLLLA 250

                         250       260
                  ....*....|....*....|....*
gi 1958668749 381 KAELLSREQKYEDGIALLRNALANQ 405
Cdd:COG2956   251 LADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
168-403 1.30e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.42  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 168 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCH 247
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 248 SFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMV 327
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 328 M----ANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALA 403
Cdd:COG0457   166 LleklEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 166-325 8.91e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 8.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 166 LRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSG 245
Cdd:COG3914    74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 246 CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG3914   154 EALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVY 233
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
199-440 2.53e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 2.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 199 LDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLK 278
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 279 GAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAtVCLEDPVTQE 358
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLG-IALEKLGRYE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 359 KAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLD 438
Cdd:COG0457   162 EALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALY 241


                  ..
gi 1958668749 439 PN 440
Cdd:COG0457   242 QY 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 176-377 3.27e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.78  E-value: 3.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYS---- 251
Cdd:COG3914     7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLElaal 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 252 -----KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAM 326
Cdd:COG3914    87 llqalGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958668749 327 VMANNVYKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALAQRPDYVKA 377
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNA-LQDLGRLEEAIAAYRRALELDPDNADA 216
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 211-346 4.48e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 4.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 211 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 290
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958668749 291 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLL 346
Cdd:COG3914   165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 235-407 5.40e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.51  E-value: 5.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 235 DQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPcrldcYEGLIE 314
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP-----DEPEAR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 315 CYLAsnsirEAMVMANNVyktlganaqtltllatvcledpvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDG 394
Cdd:COG4783    76 LNLG-----LALLKAGDY-------------------------DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|...
gi 1958668749 395 IALLRNALANQSD 407
Cdd:COG4783   126 IAALEKALELDPD 138
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 141-442 5.55e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.02  E-value: 5.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 141 AYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL 220
Cdd:TIGR02917 438 ILSYLRSGQFDKALAAAKKLEKKQ--PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNP 515

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 221 EDVENLGCRLFNISDQHAEpwVVSGCHSFYSK--RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 298
Cdd:TIGR02917 516 DDAIQRFEKVLTIDPKNLR--AILALAGLYLRtgNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEA 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 299 IRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTqEKAKTLLDKALAQRPDYVKAV 378
Cdd:TIGR02917 594 ADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNY-AKAITSLKRALELKPDNTEAQ 672

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958668749 379 VKKAELLSREQKYEDGIALLRN-ALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLDPNDQ 442
Cdd:TIGR02917 673 IGLAQLLLAAKRTESAKKIAKSlQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ 737
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 269-441 6.24e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.51  E-value: 6.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 269 SNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVmannvyktlganaqtltllat 348
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIV--------------------- 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 349 vcledpvtqekaktLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVSVNEYQEA 427
Cdd:COG4783    60 --------------LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPeAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|....
gi 1958668749 428 MDQYSIALSLDPND 441
Cdd:COG4783   126 IAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 263-384 7.49e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 7.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 263 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQT 342
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1958668749 343 LTLLATVCLE--DPvtqEKAKTLLDKALAQRPDYVKAVVKKAEL 384
Cdd:COG4235    88 LYLLGLAAFQqgDY---AEAIAAWQKLLALLPADAPARLLEASI 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 210-325 6.57e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 6.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 210 YGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQ 289
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1958668749 290 EAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 78-441 1.24e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 1.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749  78 YKKAGQERPSVTSYKEVLRQCPLALDA--ILGLLSL---SVKGAE-----VASMTMNVIQTVPNLdwlsvwikAYAFVHT 147
Cdd:TIGR02917  32 YLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIYLalgDYAAAEkelrkALSLGYPKNQVLPLL--------ARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 148 GDNSRAINTicsLEKKSLLRDN--VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVEN 225
Cdd:TIGR02917 104 GKFQQVLDE---LPGKTLLDDEgaAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 226 LGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCR 305
Cdd:TIGR02917 181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 306 LDC--YEGLIEcyLASNSIREAMvmaNNVYKTLGANAQTLT--LLATVCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKK 381
Cdd:TIGR02917 261 PLAhyLKALVD--FQKKNYEDAR---ETLQDALKSAPEYLPalLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLL 335

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958668749 382 AELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSLDPND 441
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGlDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPEN 396
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 176-303 4.92e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 4.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 176 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 255
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1958668749 256 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
339-448 8.03e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.47  E-value: 8.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 339 NAQTLTLLATVC--LEDPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI-LG 415
Cdd:COG0457     7 DAEAYNNLGLAYrrLGRY---EEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNnLG 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1958668749 416 DFLVSVNEYQEAMDQYSIALSLDPNDQKSLEGM 448
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNL 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 254-460 3.54e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 3.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 254 YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVY 333
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 334 KTLGANAQTLTLLATVCL--EDPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVL 410
Cdd:TIGR02917 459 KKQPDNASLHNLLGAIYLgkGDL---AKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTiDPKNLRA 535

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958668749 411 HRILGDFLVSVNEYQEAMDQYSIALSLDPND-QKSLEGMQKMEKEGSPTDA 460
Cdd:TIGR02917 536 ILALAGLYLRTGNEEEAVAWLEKAAELNPQEiEPALALAQYYLGKGQLKKA 586
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 359-445 1.15e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 359 KAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSL 437
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                  ....*...
gi 1958668749 438 DPNDQKSL 445
Cdd:COG4235    81 DPDNPEAL 88
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
358-440 1.19e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 358 EKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVSVNEYQEAMDQYSIALSL 437
Cdd:COG3063     9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                  ...
gi 1958668749 438 DPN 440
Cdd:COG3063    89 DPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 169-441 1.69e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 169 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHS 248
Cdd:TIGR02917 532 NLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQ 611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 249 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVM 328
Cdd:TIGR02917 612 LAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKI 691

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 329 ANNVYKTLGANAQTLTLLATVCLEDPVTQEkAKTLLDKALAQRPDyVKAVVKKAELLSREQKYEDGIALLRNALANQ-SD 407
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPA-AIQAYRKALKRAPS-SQNAIKLHRALLASGNTAEAVKTLEAWLKTHpND 769

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1958668749 408 CVLHRILGDFLVSVNEYQEAMDQYSIALSLDPND 441
Cdd:TIGR02917 770 AVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDN 803
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 190-303 2.19e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 190 VLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNS 269
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1958668749 270 NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 358-441 2.60e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 358 EKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVSVNEYQEAMDQYSIALS 436
Cdd:COG4235    34 DEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPeALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                  ....*
gi 1958668749 437 LDPND 441
Cdd:COG4235   114 LLPAD 118
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 195-325 1.74e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 1.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 195 QAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQA 274
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958668749 275 LLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 325
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 264-445 3.18e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 3.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 264 AIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNvyKTLGANAQTL 343
Cdd:TIGR02917  48 ALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPG--KTLLDDEGAA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 344 TLLATV-----CLEDPvtqEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDF 417
Cdd:TIGR02917 126 ELLALRglaylGLGQL---ELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVdALLLKGDL 202

                         170       180
                  ....*....|....*....|....*...
gi 1958668749 418 LVSVNEYQEAMDQYSIALSLDPNDQKSL 445
Cdd:TIGR02917 203 LLSLGNIELALAAYRKAIALRPNNIAVL 230
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 358-439 3.84e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 3.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 358 EKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVSVNEYQEAMDQYSIALS 436
Cdd:COG5010    71 EESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAlSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150


                  ...
gi 1958668749 437 LDP 439
Cdd:COG5010   151 TSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
179-303 1.04e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 179 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 258
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1958668749 259 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 32-325 1.07e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749  32 PSEIEVKYKMAECYTMLKLDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 107
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 108 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 186
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 187 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 237
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 238 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 314
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1958668749 315 CYLASNSIREA 325
Cdd:TIGR02917 880 ALLATGRKAEA 890
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
245-369 1.18e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 245 GCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCrlDCYEGLIECylasnsIRE 324
Cdd:COG4785   114 GLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN--DPERALWLY------LAE 185

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1958668749 325 AMVMANNVYKTLGANAQTLTLLatvcLEDPvtqEKAKTLLDKALA 369
Cdd:COG4785   186 RKLDPEKALALLLEDWATAYLL----QGDT---EEARELFKLALA 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 194-303 1.27e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 194 EQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQ 273
Cdd:COG5010    44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123

                          90       100       110
                  ....*....|....*....|....*....|
gi 1958668749 274 ALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:COG5010   124 AYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 253-372 4.32e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 4.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 253 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNV 332
Cdd:COG5010    35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1958668749 333 YKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALAQRP 372
Cdd:COG5010   115 LALSPDNPNAYSNLAAL-LLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
281-407 6.55e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 281 ALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVmannvyktlganaqtltllatvcledpvtqeka 360
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--------------------------------- 47

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958668749 361 ktlLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSD 407
Cdd:COG3063    48 ---LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 272-303 1.01e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.01e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1958668749  272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
214-441 1.36e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.28  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 214 LAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAK-AIQLNSNSVQALLLKGAALRNMGRVQEAI 292
Cdd:COG4785    14 LAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIdRALALPDLAQLYYERGVAYDSLGDYDLAI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958668749 293 IHFREAIRLAPCRLDCYEGLIECYLASNSIREAmvmannvyktlganaqtltllatvcLEDpvtqekaktlLDKALAQRP 372
Cdd:COG4785    94 ADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA-------------------------LED----------FDRALELDP 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958668749 373 DYVKAvvkkaeLLSReqkyedGIALLRnalanqsdcvlhriLGDflvsvneYQEAMDQYSIALSLDPND 441
Cdd:COG4785   139 DYAYA------YLNR------GIALYY--------------LGR-------YELAIADLEKALELDPND 174
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 272-303 1.44e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.35  E-value: 1.44e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1958668749 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
272-303 1.81e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 1.81e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1958668749 272 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 303
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 165-222 8.91e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.52  E-value: 8.91e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958668749 165 LLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLED 222
Cdd:COG4235    46 LDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH