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Conserved domains on  [gi|1958665595|ref|XP_038944310|]
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collagen alpha-1(VIII) chain isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
C1Q smart00110
Complement component C1q domain; Globular domain found in many collagens and eponymously in ...
 613-744 9.90e-65

Complement component C1q domain; Globular domain found in many collagens and eponymously in complement C1q. When part of full length proteins these domains form a 'bouquet' due to the multimerization of heterotrimers. The C1q fold is similar to that of tumour necrosis factor.


:

Pssm-ID: 128420  Cd Length: 135  Bit Score: 211.01  E-value: 9.90e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595  613 YEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEY 692
Cdd:smart00110   5 QPRSAFSVIRSNRPPPPGQPIRFDKVLYNQQGHYDPRTGKFTCPVPGVYYFSYHVESKGRNVKVSLMKNGIQVMSTYDEY 84

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958665595  693 KKGFLDQASGSAVLLLRPGDRVFLQMPSEQaAGLYAGQYVHSSFSGYLLYPM 744
Cdd:smart00110  85 QKGLYDVASGGALLQLRQGDQVWLELPDEK-NGLYAGEYVDSTFSGFLLFPD 135
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 357-502 2.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 60.30  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 357 PGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLpgipgpmgppgaigfPGPKGEGGIVGPQGPPGPKGEPGLQG 436
Cdd:NF038329  122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGE---------------KGPAGPQGEAGPQGPAGKDGEAGAKG 186

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958665595 437 FPG---KPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLL--GPKGEPGIPGDQGLQGPPGIPG 502
Cdd:NF038329  187 PAGekgPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAG 257
 
Name Accession Description Interval E-value
C1Q smart00110
Complement component C1q domain; Globular domain found in many collagens and eponymously in ...
 613-744 9.90e-65

Complement component C1q domain; Globular domain found in many collagens and eponymously in complement C1q. When part of full length proteins these domains form a 'bouquet' due to the multimerization of heterotrimers. The C1q fold is similar to that of tumour necrosis factor.


Pssm-ID: 128420  Cd Length: 135  Bit Score: 211.01  E-value: 9.90e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595  613 YEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEY 692
Cdd:smart00110   5 QPRSAFSVIRSNRPPPPGQPIRFDKVLYNQQGHYDPRTGKFTCPVPGVYYFSYHVESKGRNVKVSLMKNGIQVMSTYDEY 84

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958665595  693 KKGFLDQASGSAVLLLRPGDRVFLQMPSEQaAGLYAGQYVHSSFSGYLLYPM 744
Cdd:smart00110  85 QKGLYDVASGGALLQLRQGDQVWLELPDEK-NGLYAGEYVDSTFSGFLLFPD 135
C1q pfam00386
C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement ...
 617-741 1.10e-50

C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement system.


Pssm-ID: 395310 [Multi-domain]  Cd Length: 126  Bit Score: 172.85  E-value: 1.10e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 617 AFTAELTVPFP-PVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVH-CKGGNVWVALFKNNEPMMYTYDEYKK 694
Cdd:pfam00386   1 AFSAGRTTGLTaPNEQPVRFDKVLTNIGGHYDPATGKFTCPVPGVYYFSYHITtVDGKSLYVSLVKNGQEVVSFYDQPQK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1958665595 695 GFLDQASGSAVLLLRPGDRVFLQMPSEQaaGLYAGQY-VHSSFSGYLL 741
Cdd:pfam00386  81 GSLDVASGSVVLELQRGDEVWLQLTGYN--GLYYDGSdTDSTFSGFLL 126
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 357-502 2.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 60.30  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 357 PGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLpgipgpmgppgaigfPGPKGEGGIVGPQGPPGPKGEPGLQG 436
Cdd:NF038329  122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGE---------------KGPAGPQGEAGPQGPAGKDGEAGAKG 186

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958665595 437 FPG---KPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLL--GPKGEPGIPGDQGLQGPPGIPG 502
Cdd:NF038329  187 PAGekgPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAG 257
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 410-549 2.72e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 410 FPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIP 489
Cdd:NF038329  115 GDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQ 194

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 490 GDQGLQGPPGIPGIAGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPG 549
Cdd:NF038329  195 GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDG 254
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 448-502 1.93e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.56  E-value: 1.93e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958665595 448 GPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 502
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 274-477 1.42e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.36  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 274 KPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPG-------VGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 346
Cdd:NF038329  139 DRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGeagakgpAGEKGPQGPRGETGPAGEQGPAGPAGPDGEA 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 347 GLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 426
Cdd:NF038329  219 GPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLP 298

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958665595 427 GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGhKGLPGLPGVP 477
Cdd:NF038329  299 GKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG-KPAPKTPEVP 348
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 177-498 1.48e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 41.81  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 177 GAKGEIGPKGEigpmgipgpqgppgphglpgigkpggPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGfgmpglpglkg 256
Cdd:NF038329  117 GEKGEPGPAGP--------------------------AGPAGEQGPRGDRGETGPAGPAGPPGPQGERG----------- 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 257 ppgmhgppgpvglpgvgKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPG-VGKPGQDGIPGQPGFPGGKG 335
Cdd:NF038329  160 -----------------EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGpAGEQGPAGPAGPDGEAGPAG 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 336 EQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGApgiggppgepglpgipgpmgppgaigfPGPKG 415
Cdd:NF038329  223 EDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP---------------------------DGPDG 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 416 EggivgpqgppgpkgepglQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQ 495
Cdd:NF038329  276 K------------------DGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQP 337


                  ...
gi 1958665595 496 GPP 498
Cdd:NF038329  338 GKP 340
 
Name Accession Description Interval E-value
C1Q smart00110
Complement component C1q domain; Globular domain found in many collagens and eponymously in ...
 613-744 9.90e-65

Complement component C1q domain; Globular domain found in many collagens and eponymously in complement C1q. When part of full length proteins these domains form a 'bouquet' due to the multimerization of heterotrimers. The C1q fold is similar to that of tumour necrosis factor.


Pssm-ID: 128420  Cd Length: 135  Bit Score: 211.01  E-value: 9.90e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595  613 YEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEY 692
Cdd:smart00110   5 QPRSAFSVIRSNRPPPPGQPIRFDKVLYNQQGHYDPRTGKFTCPVPGVYYFSYHVESKGRNVKVSLMKNGIQVMSTYDEY 84

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958665595  693 KKGFLDQASGSAVLLLRPGDRVFLQMPSEQaAGLYAGQYVHSSFSGYLLYPM 744
Cdd:smart00110  85 QKGLYDVASGGALLQLRQGDQVWLELPDEK-NGLYAGEYVDSTFSGFLLFPD 135
C1q pfam00386
C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement ...
 617-741 1.10e-50

C1q domain; C1q is a subunit of the C1 enzyme complex that activates the serum complement system.


Pssm-ID: 395310 [Multi-domain]  Cd Length: 126  Bit Score: 172.85  E-value: 1.10e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 617 AFTAELTVPFP-PVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVH-CKGGNVWVALFKNNEPMMYTYDEYKK 694
Cdd:pfam00386   1 AFSAGRTTGLTaPNEQPVRFDKVLTNIGGHYDPATGKFTCPVPGVYYFSYHITtVDGKSLYVSLVKNGQEVVSFYDQPQK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1958665595 695 GFLDQASGSAVLLLRPGDRVFLQMPSEQaaGLYAGQY-VHSSFSGYLL 741
Cdd:pfam00386  81 GSLDVASGSVVLELQRGDEVWLQLTGYN--GLYYDGSdTDSTFSGFLL 126
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 357-502 2.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 60.30  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 357 PGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLpgipgpmgppgaigfPGPKGEGGIVGPQGPPGPKGEPGLQG 436
Cdd:NF038329  122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGE---------------KGPAGPQGEAGPQGPAGKDGEAGAKG 186

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958665595 437 FPG---KPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLL--GPKGEPGIPGDQGLQGPPGIPG 502
Cdd:NF038329  187 PAGekgPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAG 257
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 410-549 2.72e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 410 FPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIP 489
Cdd:NF038329  115 GDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQ 194

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 490 GDQGLQGPPGIPGIAGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPG 549
Cdd:NF038329  195 GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDG 254
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 448-502 1.93e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.56  E-value: 1.93e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958665595 448 GPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 502
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 274-477 1.42e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.36  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 274 KPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPG-------VGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 346
Cdd:NF038329  139 DRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGeagakgpAGEKGPQGPRGETGPAGEQGPAGPAGPDGEA 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 347 GLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 426
Cdd:NF038329  219 GPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLP 298

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958665595 427 GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGhKGLPGLPGVP 477
Cdd:NF038329  299 GKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG-KPAPKTPEVP 348
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 439-493 1.83e-05

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 42.48  E-value: 1.83e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1958665595 439 GKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQG 493
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 434-482 1.02e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 1.02e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1958665595 434 LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGP 482
Cdd:pfam01391   8 PPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 177-498 1.48e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 41.81  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 177 GAKGEIGPKGEigpmgipgpqgppgphglpgigkpggPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGfgmpglpglkg 256
Cdd:NF038329  117 GEKGEPGPAGP--------------------------AGPAGEQGPRGDRGETGPAGPAGPPGPQGERG----------- 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 257 ppgmhgppgpvglpgvgKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPG-VGKPGQDGIPGQPGFPGGKG 335
Cdd:NF038329  160 -----------------EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGpAGEQGPAGPAGPDGEAGPAG 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 336 EQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGApgiggppgepglpgipgpmgppgaigfPGPKG 415
Cdd:NF038329  223 EDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP---------------------------DGPDG 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958665595 416 EggivgpqgppgpkgepglQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQ 495
Cdd:NF038329  276 K------------------DGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQP 337


                  ...
gi 1958665595 496 GPP 498
Cdd:NF038329  338 GKP 340
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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