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Concise Results
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solute carrier family 38 member 10 isoform X10 [Rattus norvegicus]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
SLC5-6-like_sbd super family
cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
6-320
1.29e-30
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.
The actual alignment was detected with superfamily member pfam01490 :Pssm-ID: 444915
Cd Length: 410
Bit Score: 125.88
E-value: 1.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 6 T S K W GL V T N VV N S I V G VS VL TM P FC FKQ C G IVL G AL LL VFCSWMTHQSCMF LV KSA ----- SLSKRRT Y AG L AFHAY G KA 80
Cdd:pfam01490 3 I S A W QA V F N LI N A I I G AG VL SL P YA FKQ L G WIP G LI LL LIVGLISLYTAHL LV RCS kevpv TGKRNKS Y GD L GYRLL G PK 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 81 G KM L VETSMIGLML G S CI TFYVVI GD LGSNF F APLLG lqv T RTFRVFLLFAVSLC I VL PLS LQR N MM A - SI qs F S AM A LL 159
Cdd:pfam01490 83 G RL L ILFAILLNLF G V CI SYLIFA GD NLPAI F DSFFD --- T CPISLVYFIIIFGL I FI PLS FIP N LS A l SI -- L S LL A AV 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 160 FYTVFMFVI VLS SFKHGLFSG Q --- W L QRVSY I RWE G V F RCVP I FGMS F ACQSQV LP TYDSLDE PS V - K T M SS I FASSLN 235
Cdd:pfam01490 158 SSLYYIVIL VLS VAEGIVLTA Q gvg H L GSKTN I KLA G T F LAIG I IVFA F EGHAVL LP IQNEMKN PS K f K A M TK I LLTAII 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 236 VV T AF Y V ---------------------------------------------------------- MQKDGTFAAGGYMPP 257
Cdd:pfam01490 238 IA T VL Y I liglvgylafgdnvkgnillnlpksawlidianlllvlhvilsfplqlfpirqivenl LFRKEAPFGASGKNN 317
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659220 258 ---- L RFK V LTLSV V FG T MVGGVMI P NVETI L GFT GAT MGSLIC FI C P A L IYK K AH K NAPSA Q VV LW 320
Cdd:pfam01490 318 pksk L LRV V IRSGL V VI T YLIAISV P FFGDL L SLV GAT SCAPLS FI L P P L FHL K LK K TKKKS Q EK LW 384
PTZ00121 super family
cl31754
MAEBL; Provisional
335-1024
5.05e-08
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121 :Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 57.46
E-value: 5.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 335 SVS EEA PLDLTQGARSGQRGD AE G A M K V E A AR LSVQDPV V VM A --- ED SQ -- E KLKP AED KEVL E Q A ---- QIKGPVDVP 405
Cdd:PTZ00121 1115 RKA EEA KKKAEDARKAEEARK AE D A R K A E E AR KAEDAKR V EI A rka ED AR ka E EARK AED AKKA E A A rkae EVRKAEELR 1194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 406 GGDTPKEKQE A AQLDRPGQGIAVPMG E - A HRH E PPIPHDKVVV D EGQDQEGP EE KKPPPKLPD E GDPA --- G R G Q G A PLL 481
Cdd:PTZ00121 1195 KAEDARKAEA A RKAEEERKAEEARKA E d A KKA E AVKKAEEAKK D AEEAKKAE EE RNNEEIRKF E EARM ahf A R R Q A A IKA 1274
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 482 P E SE K KQDPERG EE G K RPEQVLAVG E I ---- E RPQ K IP EA NGQPPVQPRK E DSRPGNRDLHPVPQ ----- A RVSVELNDL 552
Cdd:PTZ00121 1275 E E AR K ADELKKA EE K K KADEAKKAE E K kkad E AKK K AE EA KKADEAKKKA E EAKKKADAAKKKAE eakka A EAAKAEAEA 1354
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 553 V A G E GKESAQ KA GG A PW K PM E SAVESNIGG K AGLAVQRPE ----------- A A EQRE K NE A EQPGG D Q A GS K L E A ----- 616
Cdd:PTZ00121 1355 A A D E AEAAEE KA EA A EK K KE E AKKKADAAK K KAEEKKKAD eakkkaeedkk K A DELK K AA A AKKKA D E A KK K A E E kkkad 1434
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 617 E I KK LVA EA GR A EMLDHAVLLQVIK E --- QQVQQKRLL D QQE K L lavi E E QH K EIRQQRQEG EE D K P K PADM ---- QPEP 689
Cdd:PTZ00121 1435 E A KK KAE EA KK A DEAKKKAEEAKKA E eak KKAEEAKKA D EAK K K ---- A E EA K KADEAKKKA EE A K K K ADEA kkaa EAKK 1510
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 690 G A AVLRGQ EE -- E A EH A GAPD E -- H A G E TLEDNPSQPLQPVLG A PRGHP A PSQD K GQHP -- L EE V K VL A G R DLADL ---- 759
Cdd:PTZ00121 1511 K A DEAKKA EE ak K A DE A KKAE E ak K A D E AKKAEEKKKADELKK A EELKK A EEKK K AEEA kk A EE D K NM A L R KAEEA kkae 1590
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 760 ------ PAGGSDT E PHGASSKLREDQ ---- K GAA LK V AE AVR K L V pgdl E PVH K PDPA E VP K SP E KQL A K E VARQRQDVF 829
Cdd:PTZ00121 1591 eariee VMKLYEE E KKMKAEEAKKAE eaki K AEE LK K AE EEK K K V ---- E QLK K KEAE E KK K AE E LKK A E E ENKIKAAEE 1666
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 830 GEGSQ E R K ETGKD A VAPGA D TQ K E A AQPLVG AE AEDSHSKSRHS E PTKV pasgpagmgf QAQARFRQEPQVIFD K SQDSH 909
Cdd:PTZ00121 1667 AKKAE E D K KKAEE A KKAEE D EK K A A EALKKE AE EAKKAEELKKK E AEEK ---------- KKAEELKKAEEENKI K AEEAK 1736
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 910 P E VRSEGPRGVGIPAE E QHRGRG A AAMQ EE KQRPDPNSGP K L AV PG --- D QKP E NAKPNR D L K V qagsdlrrrrrdlasp 986
Cdd:PTZ00121 1737 K E AEEDKKKAEEAKKD E EEKKKI A HLKK EE EKKAEEIRKE K E AV IE eel D EED E KRRMEV D K K I ---------------- 1800
730 740 750
....*....|....*....|....*....|....*...
gi 1958659220 987 pe QELAPKDGV II SFNSLP N VQV ND LRSAL D TQLRQA A 1024
Cdd:PTZ00121 1801 -- KDIFDNFAN II EGGKEG N LVI ND SKEME D SAIKEV A 1836
Name
Accession
Description
Interval
E-value
Aa_trans
pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
6-320
1.29e-30
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.
Pssm-ID: 279788
Cd Length: 410
Bit Score: 125.88
E-value: 1.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 6 T S K W GL V T N VV N S I V G VS VL TM P FC FKQ C G IVL G AL LL VFCSWMTHQSCMF LV KSA ----- SLSKRRT Y AG L AFHAY G KA 80
Cdd:pfam01490 3 I S A W QA V F N LI N A I I G AG VL SL P YA FKQ L G WIP G LI LL LIVGLISLYTAHL LV RCS kevpv TGKRNKS Y GD L GYRLL G PK 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 81 G KM L VETSMIGLML G S CI TFYVVI GD LGSNF F APLLG lqv T RTFRVFLLFAVSLC I VL PLS LQR N MM A - SI qs F S AM A LL 159
Cdd:pfam01490 83 G RL L ILFAILLNLF G V CI SYLIFA GD NLPAI F DSFFD --- T CPISLVYFIIIFGL I FI PLS FIP N LS A l SI -- L S LL A AV 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 160 FYTVFMFVI VLS SFKHGLFSG Q --- W L QRVSY I RWE G V F RCVP I FGMS F ACQSQV LP TYDSLDE PS V - K T M SS I FASSLN 235
Cdd:pfam01490 158 SSLYYIVIL VLS VAEGIVLTA Q gvg H L GSKTN I KLA G T F LAIG I IVFA F EGHAVL LP IQNEMKN PS K f K A M TK I LLTAII 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 236 VV T AF Y V ---------------------------------------------------------- MQKDGTFAAGGYMPP 257
Cdd:pfam01490 238 IA T VL Y I liglvgylafgdnvkgnillnlpksawlidianlllvlhvilsfplqlfpirqivenl LFRKEAPFGASGKNN 317
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659220 258 ---- L RFK V LTLSV V FG T MVGGVMI P NVETI L GFT GAT MGSLIC FI C P A L IYK K AH K NAPSA Q VV LW 320
Cdd:pfam01490 318 pksk L LRV V IRSGL V VI T YLIAISV P FFGDL L SLV GAT SCAPLS FI L P P L FHL K LK K TKKKS Q EK LW 384
PTZ00206
PTZ00206
amino acid transporter; Provisional
14-305
7.34e-11
amino acid transporter; Provisional
Pssm-ID: 240313
Cd Length: 467
Bit Score: 65.66
E-value: 7.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 14 N VVN S I VG VSVLTM P FCFKQC G I V LGALL L VFCSW MT HQ S CMF L VKS A SLSKR RTY A G L A FHAY G KA G KML V ETSMIGLM 93
Cdd:PTZ00206 68 N IAS S T VG AGIVGL P SAANSS G L V MAMIY L IIITA MT IF S IYA L GVA A DKTNI RTY E G V A RVLL G PW G SYY V AATRAFHG 147
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 94 LGS C ITFYVVI GD LG S nff A P L L G LQV ----- TRTFRVF L LFAVS LC IV LPL SLQ R N m MA S IQSF S AM A LL F YTVFMF VI 168
Cdd:PTZ00206 148 FSA C VAYVISV GD IL S --- A T L K G TNA pdflk QKSGNRL L TSLMW LC FM LPL VIP R H - ID S LRYV S TI A VS F MVYLVI VI 223
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 169 V LS S FKH GL fs GQWLQR VS Y -------- I RWEGVF R CVP --- I F GMSFAC Q SQVLPT Y DSLDEP SV KTMSSIFASSLNVV 237
Cdd:PTZ00206 224 V VH S CMN GL -- PENIKN VS V gkddnaei I LFNSGN R AIE glg V F IFAYVF Q ITAYEV Y MDMTNR SV GKFVLASTIAMGMC 301
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 238 TAF YV MQ kdgtf A AG GYM -------------- P P LRF ------------------------------------------- 260
Cdd:PTZ00206 302 FTM YV LT ----- A FF GYM dfgrnvtgsvllmy D P VNE paimvgfvgvlvklfvsyallgmacrnalydvigwdarkvafw 376
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1958659220 261 ---- K V L TLSVV F gt MVG G VM IP NVE T I LGF T G ATM G S L IC FI C PAL IY 305
Cdd:PTZ00206 377 khci A V V TLSVV M -- LLC G LF IP KIN T V LGF A G SIS G G L LG FI L PAL LF 423
PTZ00121
PTZ00121
MAEBL; Provisional
335-1024
5.05e-08
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 57.46
E-value: 5.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 335 SVS EEA PLDLTQGARSGQRGD AE G A M K V E A AR LSVQDPV V VM A --- ED SQ -- E KLKP AED KEVL E Q A ---- QIKGPVDVP 405
Cdd:PTZ00121 1115 RKA EEA KKKAEDARKAEEARK AE D A R K A E E AR KAEDAKR V EI A rka ED AR ka E EARK AED AKKA E A A rkae EVRKAEELR 1194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 406 GGDTPKEKQE A AQLDRPGQGIAVPMG E - A HRH E PPIPHDKVVV D EGQDQEGP EE KKPPPKLPD E GDPA --- G R G Q G A PLL 481
Cdd:PTZ00121 1195 KAEDARKAEA A RKAEEERKAEEARKA E d A KKA E AVKKAEEAKK D AEEAKKAE EE RNNEEIRKF E EARM ahf A R R Q A A IKA 1274
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 482 P E SE K KQDPERG EE G K RPEQVLAVG E I ---- E RPQ K IP EA NGQPPVQPRK E DSRPGNRDLHPVPQ ----- A RVSVELNDL 552
Cdd:PTZ00121 1275 E E AR K ADELKKA EE K K KADEAKKAE E K kkad E AKK K AE EA KKADEAKKKA E EAKKKADAAKKKAE eakka A EAAKAEAEA 1354
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 553 V A G E GKESAQ KA GG A PW K PM E SAVESNIGG K AGLAVQRPE ----------- A A EQRE K NE A EQPGG D Q A GS K L E A ----- 616
Cdd:PTZ00121 1355 A A D E AEAAEE KA EA A EK K KE E AKKKADAAK K KAEEKKKAD eakkkaeedkk K A DELK K AA A AKKKA D E A KK K A E E kkkad 1434
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 617 E I KK LVA EA GR A EMLDHAVLLQVIK E --- QQVQQKRLL D QQE K L lavi E E QH K EIRQQRQEG EE D K P K PADM ---- QPEP 689
Cdd:PTZ00121 1435 E A KK KAE EA KK A DEAKKKAEEAKKA E eak KKAEEAKKA D EAK K K ---- A E EA K KADEAKKKA EE A K K K ADEA kkaa EAKK 1510
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 690 G A AVLRGQ EE -- E A EH A GAPD E -- H A G E TLEDNPSQPLQPVLG A PRGHP A PSQD K GQHP -- L EE V K VL A G R DLADL ---- 759
Cdd:PTZ00121 1511 K A DEAKKA EE ak K A DE A KKAE E ak K A D E AKKAEEKKKADELKK A EELKK A EEKK K AEEA kk A EE D K NM A L R KAEEA kkae 1590
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 760 ------ PAGGSDT E PHGASSKLREDQ ---- K GAA LK V AE AVR K L V pgdl E PVH K PDPA E VP K SP E KQL A K E VARQRQDVF 829
Cdd:PTZ00121 1591 eariee VMKLYEE E KKMKAEEAKKAE eaki K AEE LK K AE EEK K K V ---- E QLK K KEAE E KK K AE E LKK A E E ENKIKAAEE 1666
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 830 GEGSQ E R K ETGKD A VAPGA D TQ K E A AQPLVG AE AEDSHSKSRHS E PTKV pasgpagmgf QAQARFRQEPQVIFD K SQDSH 909
Cdd:PTZ00121 1667 AKKAE E D K KKAEE A KKAEE D EK K A A EALKKE AE EAKKAEELKKK E AEEK ---------- KKAEELKKAEEENKI K AEEAK 1736
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 910 P E VRSEGPRGVGIPAE E QHRGRG A AAMQ EE KQRPDPNSGP K L AV PG --- D QKP E NAKPNR D L K V qagsdlrrrrrdlasp 986
Cdd:PTZ00121 1737 K E AEEDKKKAEEAKKD E EEKKKI A HLKK EE EKKAEEIRKE K E AV IE eel D EED E KRRMEV D K K I ---------------- 1800
730 740 750
....*....|....*....|....*....|....*...
gi 1958659220 987 pe QELAPKDGV II SFNSLP N VQV ND LRSAL D TQLRQA A 1024
Cdd:PTZ00121 1801 -- KDIFDNFAN II EGGKEG N LVI ND SKEME D SAIKEV A 1836
Borrelia_P83
pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
638-793
4.62e-04
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain]
Cd Length: 489
Bit Score: 43.84
E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 638 Q VI KE Q - QVQ Q KRLLDQ Q E K L --- LAVIEE Q HK E I RQ QR QE g EEDK PKPAD MQ - P EPGAA V LRG Q EE E A E H A GAPDEHAG 712
Cdd:pfam05262 216 Q QL KE E l DKK Q IDADKA Q Q K A dfa QDNADK Q RD E V RQ KQ QE - AKNL PKPAD TS s P KEDKQ V AEN Q KR E I E K A QIEIKKND 294
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 713 E TLEDNPSQPLQPVLGAPRGHPAPSQ DK GQHPLEEVKVL A G r DL ADLPAGGSDTEPHGASSKLREDQKGAA LKV AEAVRK 792
Cdd:pfam05262 295 E EALKAKDHKAFDLKQESKASEKEAE DK ELEAQKKREPV A E - DL QKTKPQVEAQPTSLNEDAIDSSNPVYG LKV VDPITN 373
.
gi 1958659220 793 L 793
Cdd:pfam05262 374 L 374
YqiK
COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
593-702
1.29e-03
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain]
Cd Length: 439
Bit Score: 42.55
E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 593 A AEQR E KNEA eqpggd Q A GSKL EAE IKKLV AEA graemldh A VLLQ - VIK E QQ VQ QKRLLDQQ E K lla V IE E Q H KE IRQQ 671
Cdd:COG2268 240 A EAEA E LAKK ------ K A EERR EAE TARAE AEA -------- A YEIA e ANA E RE VQ RQLEIAER E R --- E IE L Q E KE AERE 302
90 100 110
....*....|....*....|....*....|.
gi 1958659220 672 RQ E G E E D KP KPA DMQPE pg AA V lrg Q E E EAE 702
Cdd:COG2268 303 EA E L E A D VR KPA EAEKQ -- AA E --- A E A EAE 328
Name
Accession
Description
Interval
E-value
Aa_trans
pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
6-320
1.29e-30
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.
Pssm-ID: 279788
Cd Length: 410
Bit Score: 125.88
E-value: 1.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 6 T S K W GL V T N VV N S I V G VS VL TM P FC FKQ C G IVL G AL LL VFCSWMTHQSCMF LV KSA ----- SLSKRRT Y AG L AFHAY G KA 80
Cdd:pfam01490 3 I S A W QA V F N LI N A I I G AG VL SL P YA FKQ L G WIP G LI LL LIVGLISLYTAHL LV RCS kevpv TGKRNKS Y GD L GYRLL G PK 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 81 G KM L VETSMIGLML G S CI TFYVVI GD LGSNF F APLLG lqv T RTFRVFLLFAVSLC I VL PLS LQR N MM A - SI qs F S AM A LL 159
Cdd:pfam01490 83 G RL L ILFAILLNLF G V CI SYLIFA GD NLPAI F DSFFD --- T CPISLVYFIIIFGL I FI PLS FIP N LS A l SI -- L S LL A AV 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 160 FYTVFMFVI VLS SFKHGLFSG Q --- W L QRVSY I RWE G V F RCVP I FGMS F ACQSQV LP TYDSLDE PS V - K T M SS I FASSLN 235
Cdd:pfam01490 158 SSLYYIVIL VLS VAEGIVLTA Q gvg H L GSKTN I KLA G T F LAIG I IVFA F EGHAVL LP IQNEMKN PS K f K A M TK I LLTAII 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 236 VV T AF Y V ---------------------------------------------------------- MQKDGTFAAGGYMPP 257
Cdd:pfam01490 238 IA T VL Y I liglvgylafgdnvkgnillnlpksawlidianlllvlhvilsfplqlfpirqivenl LFRKEAPFGASGKNN 317
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659220 258 ---- L RFK V LTLSV V FG T MVGGVMI P NVETI L GFT GAT MGSLIC FI C P A L IYK K AH K NAPSA Q VV LW 320
Cdd:pfam01490 318 pksk L LRV V IRSGL V VI T YLIAISV P FFGDL L SLV GAT SCAPLS FI L P P L FHL K LK K TKKKS Q EK LW 384
PTZ00206
PTZ00206
amino acid transporter; Provisional
14-305
7.34e-11
amino acid transporter; Provisional
Pssm-ID: 240313
Cd Length: 467
Bit Score: 65.66
E-value: 7.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 14 N VVN S I VG VSVLTM P FCFKQC G I V LGALL L VFCSW MT HQ S CMF L VKS A SLSKR RTY A G L A FHAY G KA G KML V ETSMIGLM 93
Cdd:PTZ00206 68 N IAS S T VG AGIVGL P SAANSS G L V MAMIY L IIITA MT IF S IYA L GVA A DKTNI RTY E G V A RVLL G PW G SYY V AATRAFHG 147
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 94 LGS C ITFYVVI GD LG S nff A P L L G LQV ----- TRTFRVF L LFAVS LC IV LPL SLQ R N m MA S IQSF S AM A LL F YTVFMF VI 168
Cdd:PTZ00206 148 FSA C VAYVISV GD IL S --- A T L K G TNA pdflk QKSGNRL L TSLMW LC FM LPL VIP R H - ID S LRYV S TI A VS F MVYLVI VI 223
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 169 V LS S FKH GL fs GQWLQR VS Y -------- I RWEGVF R CVP --- I F GMSFAC Q SQVLPT Y DSLDEP SV KTMSSIFASSLNVV 237
Cdd:PTZ00206 224 V VH S CMN GL -- PENIKN VS V gkddnaei I LFNSGN R AIE glg V F IFAYVF Q ITAYEV Y MDMTNR SV GKFVLASTIAMGMC 301
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 238 TAF YV MQ kdgtf A AG GYM -------------- P P LRF ------------------------------------------- 260
Cdd:PTZ00206 302 FTM YV LT ----- A FF GYM dfgrnvtgsvllmy D P VNE paimvgfvgvlvklfvsyallgmacrnalydvigwdarkvafw 376
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1958659220 261 ---- K V L TLSVV F gt MVG G VM IP NVE T I LGF T G ATM G S L IC FI C PAL IY 305
Cdd:PTZ00206 377 khci A V V TLSVV M -- LLC G LF IP KIN T V LGF A G SIS G G L LG FI L PAL LF 423
PTZ00121
PTZ00121
MAEBL; Provisional
335-1024
5.05e-08
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 57.46
E-value: 5.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 335 SVS EEA PLDLTQGARSGQRGD AE G A M K V E A AR LSVQDPV V VM A --- ED SQ -- E KLKP AED KEVL E Q A ---- QIKGPVDVP 405
Cdd:PTZ00121 1115 RKA EEA KKKAEDARKAEEARK AE D A R K A E E AR KAEDAKR V EI A rka ED AR ka E EARK AED AKKA E A A rkae EVRKAEELR 1194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 406 GGDTPKEKQE A AQLDRPGQGIAVPMG E - A HRH E PPIPHDKVVV D EGQDQEGP EE KKPPPKLPD E GDPA --- G R G Q G A PLL 481
Cdd:PTZ00121 1195 KAEDARKAEA A RKAEEERKAEEARKA E d A KKA E AVKKAEEAKK D AEEAKKAE EE RNNEEIRKF E EARM ahf A R R Q A A IKA 1274
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 482 P E SE K KQDPERG EE G K RPEQVLAVG E I ---- E RPQ K IP EA NGQPPVQPRK E DSRPGNRDLHPVPQ ----- A RVSVELNDL 552
Cdd:PTZ00121 1275 E E AR K ADELKKA EE K K KADEAKKAE E K kkad E AKK K AE EA KKADEAKKKA E EAKKKADAAKKKAE eakka A EAAKAEAEA 1354
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 553 V A G E GKESAQ KA GG A PW K PM E SAVESNIGG K AGLAVQRPE ----------- A A EQRE K NE A EQPGG D Q A GS K L E A ----- 616
Cdd:PTZ00121 1355 A A D E AEAAEE KA EA A EK K KE E AKKKADAAK K KAEEKKKAD eakkkaeedkk K A DELK K AA A AKKKA D E A KK K A E E kkkad 1434
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 617 E I KK LVA EA GR A EMLDHAVLLQVIK E --- QQVQQKRLL D QQE K L lavi E E QH K EIRQQRQEG EE D K P K PADM ---- QPEP 689
Cdd:PTZ00121 1435 E A KK KAE EA KK A DEAKKKAEEAKKA E eak KKAEEAKKA D EAK K K ---- A E EA K KADEAKKKA EE A K K K ADEA kkaa EAKK 1510
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 690 G A AVLRGQ EE -- E A EH A GAPD E -- H A G E TLEDNPSQPLQPVLG A PRGHP A PSQD K GQHP -- L EE V K VL A G R DLADL ---- 759
Cdd:PTZ00121 1511 K A DEAKKA EE ak K A DE A KKAE E ak K A D E AKKAEEKKKADELKK A EELKK A EEKK K AEEA kk A EE D K NM A L R KAEEA kkae 1590
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 760 ------ PAGGSDT E PHGASSKLREDQ ---- K GAA LK V AE AVR K L V pgdl E PVH K PDPA E VP K SP E KQL A K E VARQRQDVF 829
Cdd:PTZ00121 1591 eariee VMKLYEE E KKMKAEEAKKAE eaki K AEE LK K AE EEK K K V ---- E QLK K KEAE E KK K AE E LKK A E E ENKIKAAEE 1666
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 830 GEGSQ E R K ETGKD A VAPGA D TQ K E A AQPLVG AE AEDSHSKSRHS E PTKV pasgpagmgf QAQARFRQEPQVIFD K SQDSH 909
Cdd:PTZ00121 1667 AKKAE E D K KKAEE A KKAEE D EK K A A EALKKE AE EAKKAEELKKK E AEEK ---------- KKAEELKKAEEENKI K AEEAK 1736
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 910 P E VRSEGPRGVGIPAE E QHRGRG A AAMQ EE KQRPDPNSGP K L AV PG --- D QKP E NAKPNR D L K V qagsdlrrrrrdlasp 986
Cdd:PTZ00121 1737 K E AEEDKKKAEEAKKD E EEKKKI A HLKK EE EKKAEEIRKE K E AV IE eel D EED E KRRMEV D K K I ---------------- 1800
730 740 750
....*....|....*....|....*....|....*...
gi 1958659220 987 pe QELAPKDGV II SFNSLP N VQV ND LRSAL D TQLRQA A 1024
Cdd:PTZ00121 1801 -- KDIFDNFAN II EGGKEG N LVI ND SKEME D SAIKEV A 1836
PTZ00121
PTZ00121
MAEBL; Provisional
344-941
2.56e-06
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 52.07
E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 344 LTQG A RSGQR G D AE G A M K V E A A RLS vqdpvvvm AED SQ -- E KLKP AED KEVL E Q A qi KGPV D VPGGDTPKEKQE A AQLD r 421
Cdd:PTZ00121 1099 KAEE A KKTET G K AE E A R K A E E A KKK -------- AED AR ka E EARK AED ARKA E E A -- RKAE D AKRVEIARKAED A RKAE - 1167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 422 pgqg I A VPMGE A HRH E PPIPHDK V vvdegqd QEGP E EK K pppklpde GDP A GRGQG A PLLP E SE K KQDPERG E EG K RP E Q 501
Cdd:PTZ00121 1168 ---- E A RKAED A KKA E AARKAEE V ------- RKAE E LR K -------- AED A RKAEA A RKAE E ER K AEEARKA E DA K KA E A 1228
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 502 V LAVG E IER pq KIP EA N gqppv QPRK E DSRPGN R DLHPVPQ A RVSVELNDLV A G E GKESAQKAGGAPW K PMES A VESNIG 581
Cdd:PTZ00121 1229 V KKAE E AKK -- DAE EA K ----- KAEE E RNNEEI R KFEEARM A HFARRQAAIK A E E ARKADELKKAEEK K KADE A KKAEEK 1301
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 582 G KA GL A VQRP E A A EQRE -- K NE AE QPGGDQAGS K LE AE IK K LV AEA GR AE MLDH A VLLQVIK E QQVQQKRLLDQQE K LLA 659
Cdd:PTZ00121 1302 K KA DE A KKKA E E A KKAD ea K KK AE EAKKKADAA K KK AE EA K KA AEA AK AE AEAA A DEAEAAE E KAEAAEKKKEEAK K KAD 1381
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 660 VIEEQHK E IR --- QQRQEG EEDK p K P AD MQPEPG AA VLRGQ E -- EE AE HAGAP DE HAGETL E DNPSQPL - QPVLG A PRGH 733
Cdd:PTZ00121 1382 AAKKKAE E KK kad EAKKKA EEDK - K K AD ELKKAA AA KKKAD E ak KK AE EKKKA DE AKKKAE E AKKADEA k KKAEE A KKAE 1460
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 734 P A PSQDKGQHPLE E V K VL A -- GRDLADLPAGGSDTEPHGASS K LREDQ K GA A -- L K V AE AVR K lvpgd LEPVH K PDP A -- 807
Cdd:PTZ00121 1461 E A KKKAEEAKKAD E A K KK A ee AKKADEAKKKAEEAKKKADEA K KAAEA K KK A de A K K AE EAK K ----- ADEAK K AEE A kk 1535
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 808 -- E VP K SP EK QL A K E V a RQRQDV fgegsqe R K ETG K DAVAPGADTQKEAAQP L VG AE AEDSHSKS R HS E PT K VPASGPAG 885
Cdd:PTZ00121 1536 ad E AK K AE EK KK A D E L - KKAEEL ------- K K AEE K KKAEEAKKAEEDKNMA L RK AE EAKKAEEA R IE E VM K LYEEEKKM 1607
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659220 886 MGFQ A Q arf RQ E PQV I FDKSQDSHP E VRSEGPRGVGIP AEE QHRGRGAAAMQ EE KQ 941
Cdd:PTZ00121 1608 KAEE A K --- KA E EAK I KAEELKKAE E EKKKVEQLKKKE AEE KKKAEELKKAE EE NK 1660
Borrelia_P83
pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
638-793
4.62e-04
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain]
Cd Length: 489
Bit Score: 43.84
E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 638 Q VI KE Q - QVQ Q KRLLDQ Q E K L --- LAVIEE Q HK E I RQ QR QE g EEDK PKPAD MQ - P EPGAA V LRG Q EE E A E H A GAPDEHAG 712
Cdd:pfam05262 216 Q QL KE E l DKK Q IDADKA Q Q K A dfa QDNADK Q RD E V RQ KQ QE - AKNL PKPAD TS s P KEDKQ V AEN Q KR E I E K A QIEIKKND 294
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 713 E TLEDNPSQPLQPVLGAPRGHPAPSQ DK GQHPLEEVKVL A G r DL ADLPAGGSDTEPHGASSKLREDQKGAA LKV AEAVRK 792
Cdd:pfam05262 295 E EALKAKDHKAFDLKQESKASEKEAE DK ELEAQKKREPV A E - DL QKTKPQVEAQPTSLNEDAIDSSNPVYG LKV VDPITN 373
.
gi 1958659220 793 L 793
Cdd:pfam05262 374 L 374
YqiK
COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
593-702
1.29e-03
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain]
Cd Length: 439
Bit Score: 42.55
E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 593 A AEQR E KNEA eqpggd Q A GSKL EAE IKKLV AEA graemldh A VLLQ - VIK E QQ VQ QKRLLDQQ E K lla V IE E Q H KE IRQQ 671
Cdd:COG2268 240 A EAEA E LAKK ------ K A EERR EAE TARAE AEA -------- A YEIA e ANA E RE VQ RQLEIAER E R --- E IE L Q E KE AERE 302
90 100 110
....*....|....*....|....*....|.
gi 1958659220 672 RQ E G E E D KP KPA DMQPE pg AA V lrg Q E E EAE 702
Cdd:COG2268 303 EA E L E A D VR KPA EAEKQ -- AA E --- A E A EAE 328
Ion_trans
pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
97-243
3.87e-03
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.
Pssm-ID: 459842 [Multi-domain]
Cd Length: 238
Bit Score: 40.33
E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 97 CIT F Y VV IG --- D L GSNFFAP L L GL Q V T R TF R VFL L F av S L CIV L P l S L QRNMMAS I Q S FSAMAL L FYTVFM F VIVLSSF 173
Cdd:pfam00520 70 ILD F V VV LP sli S L VLSSVGS L S GL R V L R LL R LLR L L -- R L IRR L E - G L RTLVNSL I R S LKSLGN L LLLLLL F LFIFAII 146
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659220 174 KHG LF S G QWLQRVSYIRWEGV F R cvp I F GMS F ACQS Q VLP T ------- YD SL D EPSVKTMSSI F A s S LNVVTA F YVM 243
Cdd:pfam00520 147 GYQ LF G G KLKTWENPDNGRTN F D --- N F PNA F LWLF Q TMT T egwgdim YD TI D GKGEFWAYIY F V - S FIILGG F LLL 219
PRK07764
PRK07764
DNA polymerase III subunits gamma and tau; Validated
516-936
5.08e-03
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain]
Cd Length: 824
Bit Score: 40.74
E-value: 5.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 516 E A NGQPPVQPRKEDSRPGNRDLH P V P QARVSVELNDLV A GE G KESAQKAGG AP WK --- P MES A VESNIGGK A GLAVQR P E 592
Cdd:PRK07764 410 P A PAAAAPAAAAAPAPAAAPQPA P A P APAPAPPSPAGN A PA G GAPSPPPAA AP SA qpa P APA A APEPTAAP A PAPPAA P A 489
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 593 - AA EQREKNEAEQ P G G DQAGSK L E --- A EI KKL V AEAG R --- A EM L DH A VL L Q V IKEQQ V ------- QQK R LLDQQ -- E K 656
Cdd:PRK07764 490 p AA APAAPAAPAA P A G ADDAAT L R erw P EI LAA V PKRS R ktw A IL L PE A TV L G V RGDTL V lgfstgg LAR R FASPG na E V 569
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 657 L LAVIE E QH keirqqrqe G EEDKP kpadmqpepgaavlrgqee EA EHAG AP DEHA GE TLEDNP S QPLQPVLGA P RGHP AP 736
Cdd:PRK07764 570 L VTALA E EL --------- G GDWQV ------------------- EA VVGP AP GAAG GE GPPAPA S SGPPEEAAR P AAPA AP 621
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 737 SQDKGQH P leevkvlagrdladlpa G G SDTE P HG AS SKLREDQKGAALKVAEAVRKLVPGDLEPVHKPDPAEV P KS P EKQ 816
Cdd:PRK07764 622 AAPAAPA P ----------------- A G AAAA P AE AS AAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA P AA P PPA 684
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659220 817 L A KEVARQRQ dvfg EGSQERKETGKD A VA P GADTQKE AAQP LVG A EAEDSH S KSRHSEPTKV P ASGPAGMGFQ A Q A RFRQ 896
Cdd:PRK07764 685 P A PAAPAAPA ---- GAAPAQPAPAPA A TP P AGQADDP AAQP PQA A QGASAP S PAADDPVPLP P EPDDPPDPAG A P A QPPP 760
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1958659220 897 E P QVIFDKSQDSH P EVRSEGPRGV ------ GIPAE E QH R GRGAA AM 936
Cdd:PRK07764 761 P P APAPAAAPAAA P PPSPPSEEEE maedda PSMDD E DR R DAEEV AM 806
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01