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Conserved domains on  [gi|1958657797|ref|XP_038941670|]
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microtubule-associated protein tau isoform X3 [Rattus norvegicus]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 575-604 1.15e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 67.82  E-value: 1.15e-14
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 575 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 604
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 606-635 7.86e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.04  E-value: 7.86e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 606 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 635
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 637-667 5.18e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 54.72  E-value: 5.18e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1958657797 637 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 667
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 192-562 5.92e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  192 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 254
Cdd:PHA03247  2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  255 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 331
Cdd:PHA03247  2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  332 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 411
Cdd:PHA03247  2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  412 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 487
Cdd:PHA03247  2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958657797  488 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 562
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 575-604 1.15e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 67.82  E-value: 1.15e-14
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 575 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 604
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 606-635 7.86e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.04  E-value: 7.86e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 606 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 635
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 637-667 5.18e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 54.72  E-value: 5.18e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1958657797 637 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 667
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 192-562 5.92e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  192 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 254
Cdd:PHA03247  2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  255 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 331
Cdd:PHA03247  2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  332 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 411
Cdd:PHA03247  2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  412 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 487
Cdd:PHA03247  2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958657797  488 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 562
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 317-551 8.47e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.64  E-value: 8.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 317 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTP-----SNRPCLSPTRPTPGSSDPLIKPSS 391
Cdd:pfam17823 145 PRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPttaasSAPATLTPARGISTAATATGHPAA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 392 pavcpepATSPKYVSSVTPrngSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQ 471
Cdd:pfam17823 225 -------GTALAAVGNSSP---AAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARN 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 472 PqrkLPPAGAKTERGEPPKSGERSGYSSPGSPgTPGSRSRTPSLPTPPTREPKKVAVVRTP---PKSPSASksrlqtaPV 548
Cdd:pfam17823 295 P---AAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTNLAVVTTTkaqAKEPSAS-------PV 363


                  ...
gi 1958657797 549 PMP 551
Cdd:pfam17823 364 PVL 366
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 575-604 1.15e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 67.82  E-value: 1.15e-14
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 575 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 604
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 606-635 7.86e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.04  E-value: 7.86e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958657797 606 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 635
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 637-667 5.18e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 54.72  E-value: 5.18e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1958657797 637 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 667
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 192-562 5.92e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  192 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 254
Cdd:PHA03247  2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  255 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 331
Cdd:PHA03247  2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  332 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 411
Cdd:PHA03247  2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  412 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 487
Cdd:PHA03247  2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958657797  488 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 562
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PHA03247 PHA03247
large tegument protein UL36; Provisional
 233-554 6.07e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 6.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  233 PLPADFFSkvSAETQASPPEGPGTGPSEEGHEAApeftfhvEIKASAPKEQDlEGATVVGAPAEEQKARGPSVGKGTKEA 312
Cdd:PHA03247  2554 PLPPAAPP--AAPDRSVPPPRPAPRPSEPAVTSR-------ARRPDAPPQSA-RPRAPVDDRGDPRGPAPPSPLPPDTHA 2623

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  313 SLLEPTDKQPAAGLPGRP-VSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSS 391
Cdd:PHA03247  2624 PDPPPPSPSPAANEPDPHpPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPP 2703

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  392 PAVCPEPAtsPKYVSSVTPRNGSPGTKQMKLKgADGKTGAKIATPRGAATPGqkGTSNATRIPAKTTPSPKTPPGSASKQ 471
Cdd:PHA03247  2704 PPPTPEPA--PHALVSATPLPPGPAAARQASP-ALPAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAG 2778

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  472 PQRKLPP------AGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPkkvaVVRTPPKSPSASKSRLQT 545
Cdd:PHA03247  2779 PPRRLTRpavaslSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP----TAPPPPPGPPPPSLPLGG 2854


                   ....*....
gi 1958657797  546 APVPMPDLK 554
Cdd:PHA03247  2855 SVAPGGDVR 2863
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 245-523 4.42e-09

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 60.09  E-value: 4.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 245 ETQASPPEGPGTGPSEEGHEaAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQK-------ARGPSVGKGTKEASLLEP 317
Cdd:PTZ00449  515 EASGLPPKAPGDKEGEEGEH-EDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKpskiptlSKKPEFPKDPKHPKDPEE 593

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 318 TDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPscaktPSNRPcLSPTRPtpgSSDPLIKPSSPAVCPE 397
Cdd:PTZ00449  594 PKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPP-----PPQRP-SSPERP---EGPKIIKSPKPPKSPK 664

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 398 PATSPKYVSSV--TPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAK-TTPS-PKTPPGS-ASKQP 472
Cdd:PTZ00449  665 PPFDPKFKEKFydDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLpRDEEfPFEPIGDpDAEQP 744

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958657797 473 ---QRKLPPAGAKTERGEPPKSGERSG-----------YSSPGSPGTPGSRSRTPS--LPTPPTREP 523
Cdd:PTZ00449  745 ddiEFFTPPEEERTFFHETPADTPLPDilaeefkeediHAETGEPDEAMKRPDSPSehEDKPPGDHP 811
PHA03247 PHA03247
large tegument protein UL36; Provisional
 181-551 6.76e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.57  E-value: 6.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  181 EDITMDESSQESPPSQASLAPGTA-----TPQAR---SVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPE 252
Cdd:PHA03247  2541 EELASDDAGDPPPPLPPAAPPAAPdrsvpPPRPAprpSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPD 2620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  253 GPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATV--------VGAPAEEQKARGPSVGKGTKEA--------SLLE 316
Cdd:PHA03247  2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvsrprrARRLGRAAQASSPPQRPRRRAArptvgsltSLAD 2700

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  317 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPS--NRPCLSPTRPTPGSSDPlikPSSPAV 394
Cdd:PHA03247  2701 PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAP---PAAPAA 2777

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  395 CPEPATSPKYVSSVTP-RNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPP-------- 465
Cdd:PHA03247  2778 GPPRRLTRPAVASLSEsRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggsva 2857

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  466 --GSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGS----PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAS 539
Cdd:PHA03247  2858 pgGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTEsfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPP 2937

                          410
                   ....*....|..
gi 1958657797  540 KSRLQTAPVPMP 551
Cdd:PHA03247  2938 RPQPPLAPTTDP 2949
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 552-573 2.14e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 47.41  E-value: 2.14e-07
                          10        20
                  ....*....|....*....|..
gi 1958657797 552 DLKNVRSKIGSTENLKHQPGGG 573
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 244-571 1.86e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 51.71  E-value: 1.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  244 AETQASPPEGPGTGPS--EEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQ 321
Cdd:PHA03307    61 ACDRFEPPTGPPPGPGteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRP 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  322 PAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSN-------RPCLSPTRPTPGSSDPLIKPSSPAV 394
Cdd:PHA03307   141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppaepppSTPPAAASPRPPRRSSPISASASSP 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  395 CPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQR 474
Cdd:PHA03307   221 APAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSP 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  475 KLPPAGAKTERgePPKSGERSGY----------SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQ 544
Cdd:PHA03307   301 SSPGSGPAPSS--PRASSSSSSSressssstssSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSP 378

                          330       340
                   ....*....|....*....|....*..
gi 1958657797  545 TAPVPMPDLKNVRSKIGSTENLKHQPG 571
Cdd:PHA03307   379 AASAGRPTRRRARAAVAGRARRRDATG 405
PHA03378 PHA03378
EBNA-3B; Provisional
 358-551 3.21e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 47.37  E-value: 3.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 358 TSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPS---SPAVCPEPATSPKYVSSVTPRNGSPgtkqmklkgadgkTGAKIA 434
Cdd:PHA03378  618 TSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTphqPPQVEITPYKPTWTQIGHIPYQPSP-------------TGANTM 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 435 TPRGAAtPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTeRGEPPKSGERSGYSSPGSPGTPGSRSRTPS 514
Cdd:PHA03378  685 LPIQWA-PGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPG-RARPPAAAPGRARPPAAAPGRARPPAAAPG 762

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1958657797 515 LPTPPTREPKKvAVVRTPPKSPSASKSRLQTAPVPMP 551
Cdd:PHA03378  763 RARPPAAAPGA-PTPQPPPQAPPAPQQRPRGAPTPQP 798
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 191-536 9.86e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 9.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 191 ESPPSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPAdffskvsAETQASPPEGPGTGPSEEGHEAAPEFT 270
Cdd:PRK07764  379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA-------PAAAPQPAPAPAPAPAPPSPAGNAPAG 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 271 FHVEIKASAPKEQDLEGAtvvGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPVSRV----PQLK-------- 338
Cdd:PRK07764  452 GAPSPPPAAAPSAQPAPA---PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLrerwPEILaavpkrsr 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 339 ---------ARVAGVSKDR------TGNDEK-----------------------------------KAKTSTPSCAKTPS 368
Cdd:PRK07764  529 ktwaillpeATVLGVRGDTlvlgfsTGGLARrfaspgnaevlvtalaeelggdwqveavvgpapgaAGGEGPPAPASSGP 608

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 369 NRPCLSPTRPTPGSSDPLIKPSSPAVCPEPAtSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTS 448
Cdd:PRK07764  609 PEEAARPAAPAAPAAPAAPAPAGAAAAPAEA-SAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP 687

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 449 NATRIP---AKTTPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKK 525
Cdd:PRK07764  688 AAPAAPagaAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPA 767

                         410
                  ....*....|.
gi 1958657797 526 VAVVRTPPKSP 536
Cdd:PRK07764  768 AAPAAAPPPSP 778
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
258-479 1.30e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 258 PSEEGHEAAPeftfhveikASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAglpgrPVSRVPQL 337
Cdd:PRK12323  365 PGQSGGGAGP---------ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-----PARRSPAP 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 338 KARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATS--------PKYVSSVT 409
Cdd:PRK12323  431 EALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDdpppweelPPEFASPA 510

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 410 PRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGqkgtSNATRIPAKTTPSPKTPPGSASKQPQRKLPPA 479
Cdd:PRK12323  511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAPA----PAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 135-552 1.38e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  135 EATHQPLGTRPEDVERSHPASELLWQESPQKEAwGKDRLGSEEEVDEDITMDESSQESPPSQASLAPGTATPQARSVSAS 214
Cdd:PHA03307    66 EPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA-SPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSP 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  215 GVSGETTSIPGFPAEG-------SIPLPADFFSKVSAETQASPPEGPGTGPSEEGHEAAP-EFTFHVEIKASAPKEQDLE 286
Cdd:PHA03307   145 GPPPAASPPAAGASPAavasdaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPrPPRRSSPISASASSPAPAP 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  287 GATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAG-LPGRPvsrvpqlkarvagvskdrtgndekkaktSTPSCAK 365
Cdd:PHA03307   225 GRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPItLPTRI----------------------------WEASGWN 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  366 TPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSpgtkqmklkgaDGKTGAKIATPRGAATPGQK 445
Cdd:PHA03307   277 GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS-----------SSSTSSSSESSRGAAVSPGP 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  446 GTSNAtripakttPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRepkk 525
Cdd:PHA03307   346 SPSRS--------PSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPR---- 413

                          410       420
                   ....*....|....*....|....*..
gi 1958657797  526 vavvRTPPKSPSASKSRLQTAPVPMPD 552
Cdd:PHA03307   414 ----PSPLDAGAASGAFYARYPLLTPS 436
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 173-543 3.12e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  173 LGSEEEVDEDITMDESSQESPPSQASLAP---GTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQAS 249
Cdd:PHA03307    43 LVSDSAELAAVTVVAGAAACDRFEPPTGPppgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPP 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  250 PPEGPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEAS---LLEPTDKQPAAGL 326
Cdd:PHA03307   123 PASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPsspPAEPPPSTPPAAA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  327 PGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVS 406
Cdd:PHA03307   203 SPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRP 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797  407 SVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNAtripAKTTPSPKTPPGSASkqpqrklPPAGAKTERG 486
Cdd:PHA03307   283 GPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS----SSTSSSSESSRGAAV-------SPGPSPSRSP 351

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958657797  487 EPPKSGERSGYSSPGSPGTPGSRSRTPSlPTPPTREPKKVAVVRTPPKSPSASKSRL 543
Cdd:PHA03307   352 SPSRPPPPADPSSPRKRPRPSRAPSSPA-ASAGRPTRRRARAAVAGRARRRDATGRF 407
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
358-546 3.78e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.71  E-value: 3.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 358 TSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVtPRNGSPGTKQM---KLKGADGKTGAKIA 434
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-PARRSPAPEALaaaRQASARGPGGAPAP 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 435 TPRGAATPGqKGTSNATRIPAKTTPSPKTPPGSASKQ-----------PQRKLPPAGAKTERGEP---PKSGERSGYSSP 500
Cdd:PRK12323  451 APAPAAAPA-AAARPAAAGPRPVAAAAAAAPARAAPAaapapadddppPWEELPPEFASPAPAQPdaaPAGWVAESIPDP 529

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1958657797 501 G-SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTA 546
Cdd:PRK12323  530 AtADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 317-551 8.47e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.64  E-value: 8.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 317 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTP-----SNRPCLSPTRPTPGSSDPLIKPSS 391
Cdd:pfam17823 145 PRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPttaasSAPATLTPARGISTAATATGHPAA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 392 pavcpepATSPKYVSSVTPrngSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQ 471
Cdd:pfam17823 225 -------GTALAAVGNSSP---AAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARN 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 472 PqrkLPPAGAKTERGEPPKSGERSGYSSPGSPgTPGSRSRTPSLPTPPTREPKKVAVVRTP---PKSPSASksrlqtaPV 548
Cdd:pfam17823 295 P---AAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTNLAVVTTTkaqAKEPSAS-------PV 363


                  ...
gi 1958657797 549 PMP 551
Cdd:pfam17823 364 PVL 366
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
434-551 1.03e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 434 ATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTP 513
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1958657797 514 SLP--TPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMP 551
Cdd:PRK12323  452 PAPaaAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
322-551 1.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 322 PAAGLPGRPVSRVPQLKARVAGvskdrtgndekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATS 401
Cdd:PRK07003  368 PGGGVPARVAGAVPAPGARAAA------------AVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 402 PKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGA 481
Cdd:PRK07003  436 ADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 482 KTERGEPPKSGERSGYSSPGSPG--TPGSRS----------RTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVP 549
Cdd:PRK07003  516 ASREDAPAAAAPPAPEARPPTPAaaAPAARAggaaaaldvlRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQ 595


                  ..
gi 1958657797 550 MP 551
Cdd:PRK07003  596 VP 597
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 389-536 2.39e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.21  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 389 PSSPAVCPEPATSPKYVSSVTPRNG-SPGTKQMKLKGADGKTGAKIATPRgaatPGQKGTSNATRIPAKTtpspKTPPG- 466
Cdd:PTZ00449  511 PEGPEASGLPPKAPGDKEGEEGEHEdSKESDEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLS----KKPEFp 582

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 467 SASKQPQRKLPPAGAKT----ERGEPPKSGERSGYS----SPGSPGTPGSRSRTPSlPTPPT--REPKKVAVVRT--PPK 534
Cdd:PTZ00449  583 KDPKHPKDPEEPKKPKRprsaQRPTRPKSPKLPELLdipkSPKRPESPKSPKRPPP-PQRPSspERPEGPKIIKSpkPPK 661


                  ..
gi 1958657797 535 SP 536
Cdd:PTZ00449  662 SP 663
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 107-292 2.59e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 2.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 107 APDSGISDWTHQQVPSMSGAPLPPQGLREATHQPLGTRPEDVERSHP-ASELLWQESPQKEAWGKDRLGSEEEVDEDITM 185
Cdd:PRK07764  616 AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDAsDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAG 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 186 DESSQESP------PSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPEGPGTGPS 259
Cdd:PRK07764  696 AAPAQPAPapaatpPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1958657797 260 EEGHEAAPEFtfhVEIKASAPKEQDLEGATVVG 292
Cdd:PRK07764  776 PSPPSEEEEM---AEDDAPSMDDEDRRDAEEVA 805
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
250-553 3.61e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 3.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 250 PPEGPGTGPSEEGHEAAPEftfhveiKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGR 329
Cdd:PRK07003  360 PAVTGGGAPGGGVPARVAG-------AVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAP 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 330 PVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPkyvssvt 409
Cdd:PRK07003  433 PATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPA------- 505

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 410 prngspgtkqmklKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKlppAGAK--TERGE 487
Cdd:PRK07003  506 -------------AVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRN---AGMRvsSDRGA 569

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958657797 488 PPKSGERSGYSSPGSPGTPGSRsrtPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDL 553
Cdd:PRK07003  570 RAAAAAKPAAAPAAAPKPAAPR---VAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDI 632
PRK13863 PRK13863
T-DNA border endonuclease VirD2;
350-520 3.90e-03

T-DNA border endonuclease VirD2;


Pssm-ID: 237533 [Multi-domain]  Cd Length: 446  Bit Score: 40.31  E-value: 3.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 350 GNDEKKAKTSTPSCAKTPSNRPcLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKT 429
Cdd:PRK13863  223 EDHREPSQSFDTSPGEAPQGEP-ESAERPEKLQNESEVRLQEPAGSSIKADARIRVSLESERRAQPSASKIPVADDFGIE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 430 GAKIATPRGAATPGQKGTSNATRIPAKTTPSpktppgsaSKQPQRKLP------PAGAKTERGEPPKSGERSGYSSPGSP 503
Cdd:PRK13863  302 TSYVAEGDVRKLEGNSGTPRLATEVATHTTS--------ERQQRRKRPrddegePSGAKRTRLNGIAVGPEANAGEQDGR 373

                         170
                  ....*....|....*..
gi 1958657797 504 GTPGSRSRTPSLPTPPT 520
Cdd:PRK13863  374 DDPITSPAQPPRSNPLA 390
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 347-539 6.38e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.90  E-value: 6.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 347 DRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDplikpsspAVCPEPATSPKYVSSVTPrngSPGTKQmklKGAD 426
Cdd:pfam05109 435 NTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTAD--------VTSPTPAGTTSGASPVTP---SPSPRD---NGTE 500

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 427 GKTGAKIATPRGAATPGQKGTSNAtriPAKTTPSP--------KTPPGSASKQP----QRKLPPAGAKTERGEPPKSGER 494
Cdd:pfam05109 501 SKAPDMTSPTSAVTTPTPNATSPT---PAVTTPTPnatsptlgKTSPTSAVTTPtpnaTSPTPAVTTPTPNATIPTLGKT 577

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958657797 495 SGYSSPGSPgTPGSRSRTPSLPTPPTREPK-------KVAVVRTPPKSPSAS 539
Cdd:pfam05109 578 SPTSAVTTP-TPNATSPTVGETSPQANTTNhtlggtsSTPVVTSPPKNATSA 628
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 184-524 7.19e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.90  E-value: 7.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 184 TMDESSQESPPSQASLAPGTATPQAR----SVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQA---SPPEGPGT 256
Cdd:pfam05109 470 TADVTSPTPAGTTSGASPVTPSPSPRdngtESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTlgkTSPTSAVT 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 257 GPSEEGHEAAPEFTFHVEiKASAPKEQDLEGATVVGAPAEeqKARGPSVGKGTKEASllepTDKQPAAGLPGRPVSRVPQ 336
Cdd:pfam05109 550 TPTPNATSPTPAVTTPTP-NATIPTLGKTSPTSAVTTPTP--NATSPTVGETSPQAN----TTNHTLGGTSSTPVVTSPP 622

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 337 LKARVA------GVSKDRTGNDEKK----AKTSTPSCA-KTPSNRPCLSPTRPTPGSSDPLIKPSSPAV----CPEPATS 401
Cdd:pfam05109 623 KNATSAvttgqhNITSSSTSSMSLRpssiSETLSPSTSdNSTSHMPLLTSAHPTGGENITQVTPASTSThhvsTSSPAPR 702

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958657797 402 PKYVSSVT-PRNGSPGTKQMKLKGADGK-----------TGAKIATPRGAATPGQ----KGTSNATRIPAKTTPSPKTPP 465
Cdd:pfam05109 703 PGTTSQASgPGNSSTSTKPGEVNVTKGTppknatspqapSGQKTAVPTVTSTGGKanstTGGKHTTGHGARTSTEPTTDY 782

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958657797 466 GSASKQPQRK------LPPAGAKTERgeppksgERSGYSSPgsPGTpgsrSRTPSLPTPPTREPK 524
Cdd:pfam05109 783 GGDSTTPRTRynattyLPPSTSSKLR-------PRWTFTSP--PVT----TAQATVPVPPTSQPR 834
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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