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Conserved domains on  [gi|1958648340|ref|XP_038941552|]
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oxysterol-binding protein 1 isoform X1 [Rattus norvegicus]

Protein Classification

OSBP family protein( domain architecture ID 10472238)

OSBP (oxysterol-binding protein) family protein similar to oxysterol-binding protein that is a lipid transfer protein

Gene Ontology:  GO:0008289|GO:0008142|GO:0016020
SCOP:  4000415
TCDB:  2.D.1

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
148-526 0e+00

Oxysterol-binding protein;


:

Pssm-ID: 460126  Cd Length: 366  Bit Score: 522.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 148 NLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNP 227
Cdd:pfam01237   1 SLWSILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAEEDDPLERMLYVAAFAVSGYSSTRRRVKKPFNP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 228 LLGETFELDRlEENGYRSLCEQVSHHPPAAAHHAESKnGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKK 307
Cdd:pfam01237  81 LLGETFELVR-PDKGFRFIAEQVSHHPPISAFHAESK-GWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLKKTGEHYTWTK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 308 VTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQP 387
Cdd:pfam01237 159 PTTYVHNIIFGKLWVEHYGEMTITNHTTGYKAVLEFKPKGYFSSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVST 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 388 ASGENGGDARQRGHEAEESRvmLWKRNPLPKnaeNMYYFSELALTLNAWE---GGTAPTDSRLRPDQRLMENGRWDEANA 464
Cdd:pfam01237 239 GKKSSEDDSVEEQPDGESRL--LWKAGPLPN---AYYGFTSFAVTLNELTdelGKLPPTDSRLRPDQRALENGDIDEAEE 313
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958648340 465 EKQRLEEKQRLSRKKREAEAmkatedgtpyDPYKALWFERKK-DPVTKELTHVYRGEYWECKE 526
Cdd:pfam01237 314 EKLRLEEKQRARRKEREEKG----------EEWKPRWFKKVKdDPVTGEEYWKYKGGYWERRE 366
 
Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
148-526 0e+00

Oxysterol-binding protein;


Pssm-ID: 460126  Cd Length: 366  Bit Score: 522.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 148 NLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNP 227
Cdd:pfam01237   1 SLWSILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAEEDDPLERMLYVAAFAVSGYSSTRRRVKKPFNP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 228 LLGETFELDRlEENGYRSLCEQVSHHPPAAAHHAESKnGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKK 307
Cdd:pfam01237  81 LLGETFELVR-PDKGFRFIAEQVSHHPPISAFHAESK-GWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLKKTGEHYTWTK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 308 VTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQP 387
Cdd:pfam01237 159 PTTYVHNIIFGKLWVEHYGEMTITNHTTGYKAVLEFKPKGYFSSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVST 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 388 ASGENGGDARQRGHEAEESRvmLWKRNPLPKnaeNMYYFSELALTLNAWE---GGTAPTDSRLRPDQRLMENGRWDEANA 464
Cdd:pfam01237 239 GKKSSEDDSVEEQPDGESRL--LWKAGPLPN---AYYGFTSFAVTLNELTdelGKLPPTDSRLRPDQRALENGDIDEAEE 313
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958648340 465 EKQRLEEKQRLSRKKREAEAmkatedgtpyDPYKALWFERKK-DPVTKELTHVYRGEYWECKE 526
Cdd:pfam01237 314 EKLRLEEKQRARRKEREEKG----------EEWKPRWFKKVKdDPVTGEEYWKYKGGYWERRE 366
 
Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
148-526 0e+00

Oxysterol-binding protein;


Pssm-ID: 460126  Cd Length: 366  Bit Score: 522.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 148 NLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNP 227
Cdd:pfam01237   1 SLWSILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAEEDDPLERMLYVAAFAVSGYSSTRRRVKKPFNP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 228 LLGETFELDRlEENGYRSLCEQVSHHPPAAAHHAESKnGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKK 307
Cdd:pfam01237  81 LLGETFELVR-PDKGFRFIAEQVSHHPPISAFHAESK-GWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLKKTGEHYTWTK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 308 VTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQP 387
Cdd:pfam01237 159 PTTYVHNIIFGKLWVEHYGEMTITNHTTGYKAVLEFKPKGYFSSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVST 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958648340 388 ASGENGGDARQRGHEAEESRvmLWKRNPLPKnaeNMYYFSELALTLNAWE---GGTAPTDSRLRPDQRLMENGRWDEANA 464
Cdd:pfam01237 239 GKKSSEDDSVEEQPDGESRL--LWKAGPLPN---AYYGFTSFAVTLNELTdelGKLPPTDSRLRPDQRALENGDIDEAEE 313
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958648340 465 EKQRLEEKQRLSRKKREAEAmkatedgtpyDPYKALWFERKK-DPVTKELTHVYRGEYWECKE 526
Cdd:pfam01237 314 EKLRLEEKQRARRKEREEKG----------EEWKPRWFKKVKdDPVTGEEYWKYKGGYWERRE 366
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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