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Conserved domains on  [gi|1958802946|ref|XP_038939728|]
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laminin subunit alpha-1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
 25-275 7.52e-91

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


:

Pssm-ID: 214532  Cd Length: 238  Bit Score: 294.65  E-value: 7.52e-91
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946    25 QQRGLFPAILNLATNAHISANATCGEKGPEMFCKLVehvpGRPVRHAQCRVCDgnSTNPRERHPITHAIDGTN----NWW 100
Cdd:smart00136    3 RPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCD--ARNPRRSHPAENLTDGNNpnnpTWW 76

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   101 QSPSIQNGReyHWVTVTLDLRQVFQVAYVIIKAAnAPRPGNWILERSVDGVKFRPWQYYAvsdTECLTRYKITPRRGPPT 180
Cdd:smart00136   77 QSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPITK 150

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   181 YrADNEVICTSYYSKLVPLEHGEIHTSLINGRPSADDP--SPQLLEFTSARYIRLRLQRIRTLNADLMtlshrdlrDLDP 258
Cdd:smart00136  151 G-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELM--------DDRP 221

                           250
                    ....*....|....*..
gi 1958802946   259 IVTRRYYYSIKDISVGG 275
Cdd:smart00136  222 EVTRRYYYAISDIAVGG 238
Laminin_B pfam00052
Laminin B (Domain IV);
1225-1367 4.19e-49

Laminin B (Domain IV);


:

Pssm-ID: 459652  Cd Length: 136  Bit Score: 170.91  E-value: 4.19e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1225 YWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGTGTSNYEPQVLIKGGRTRKHIIYMDAPAPENGVRQDYEVGMKEEFWKYf 1304
Cdd:pfam00052    1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958802946 1305 nsVSEKHVTHSDFMSVLSNIEYILIKASYGQGLQQSRIANISMEVGRkavePAPEGKVALQLE 1367
Cdd:pfam00052   80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV----PGGSGPPASWVE 136
LamB smart00281
Laminin B domain;
572-702 3.99e-46

Laminin B domain;


:

Pssm-ID: 214597  Cd Length: 127  Bit Score: 162.05  E-value: 3.99e-46
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   572 SPYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTISTRAEGlSLQPYEEYFNVVRLVPEN 651
Cdd:smart00281    3 EPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFREEN 78

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946   652 FRDFNtRREIDRDQLMTVLANVTHLLIRANYnSAKMALYRLDSVSLDIASP 702
Cdd:smart00281   79 WQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 909-955 2.62e-12

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 62.76  E-value: 2.62e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1958802946  909 CNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDTGLGC 955
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQ 47
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1051-1099 1.76e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946 1051 CNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGYRSFPDCVPCDC 1099
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1516-1553 1.94e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.94e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958802946 1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 404-463 2.08e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 2.08e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  404 CDCDPVGSLSSVCIKddlhadlangkWPGQCPCRKGYAGDKCDRCQFGYRGFPNCVPCDC 463
Cdd:pfam00053    1 CDCNPHGSLSDTCDP-----------ETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1410-1456 3.96e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 3.96e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1410 CNCNNH---SDVCDPETGKCLnCRDHTAGDHCELCTAGYYGKVIGLPGDC 1456
Cdd:pfam00053    1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1097-1154 4.59e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 4.59e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958802946 1097 CDCDLRGTLADTCDLEQGlcsctedsgTCSCKENVLGPQCDKCRAGTFALRADNPLGC 1154
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETG---------QCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 461-507 6.28e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.43  E-value: 6.28e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  461 CDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNLKERNPEGC 507
Cdd:pfam00053    1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 958-1005 9.57e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 49.66  E-value: 9.57e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  958 CNCSGEGSISDNCTEE-GQCHCVPGVSGKQCDQCSHGFYAFQNGGCTPC 1005
Cdd:pfam00053    1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 748-796 7.84e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 7.84e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  748 PCECHGHSS---ECD-IHGICSgCTHNTTGDHCEQCLPGFYGTPSRgtPGDCQ 796
Cdd:cd00055      1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 855-907 8.56e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 8.56e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  855 PCNCSGNVDplEAGHCDSVTGECLkCLWNTDGAHCERCADGFYGDAVTAKNCR 907
Cdd:cd00055      1 PCDCNGHGS--LSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1004-1049 3.32e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.42  E-value: 3.32e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1004 PCDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGLDPE-QGCQ 1049
Cdd:cd00055      1 PCDCnghGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 277-324 2.16e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 43.11  E-value: 2.16e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  277 CICSGHAS---SCpwdeEAKQLQCQCEHNTCGESCDRCCPGFHQQPWRPGT 324
Cdd:cd00055      2 CDCNGHGSlsgQC----DPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 798-853 7.96e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 41.57  E-value: 7.96e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958802946  798 CACPLSIDSnnfSPTChltDREEVVCdQCAPGYSGAWCERCADGYYGNPTVPGGTC 853
Cdd:pfam00053    1 CDCNPHGSL---SDTC---DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1459-1513 9.13e-04

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.49  E-value: 9.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958802946 1459 CTCPHHPpfSFSPTCVLEGdsgFWCDaCLPGYEGQYCERCSAGYHGNPRAAGGSC 1513
Cdd:pfam00053    1 CDCNPHG--SLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
 
Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
 25-275 7.52e-91

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


Pssm-ID: 214532  Cd Length: 238  Bit Score: 294.65  E-value: 7.52e-91
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946    25 QQRGLFPAILNLATNAHISANATCGEKGPEMFCKLVehvpGRPVRHAQCRVCDgnSTNPRERHPITHAIDGTN----NWW 100
Cdd:smart00136    3 RPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCD--ARNPRRSHPAENLTDGNNpnnpTWW 76

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   101 QSPSIQNGReyHWVTVTLDLRQVFQVAYVIIKAAnAPRPGNWILERSVDGVKFRPWQYYAvsdTECLTRYKITPRRGPPT 180
Cdd:smart00136   77 QSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPITK 150

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   181 YrADNEVICTSYYSKLVPLEHGEIHTSLINGRPSADDP--SPQLLEFTSARYIRLRLQRIRTLNADLMtlshrdlrDLDP 258
Cdd:smart00136  151 G-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELM--------DDRP 221

                           250
                    ....*....|....*..
gi 1958802946   259 IVTRRYYYSIKDISVGG 275
Cdd:smart00136  222 EVTRRYYYAISDIAVGG 238
Laminin_N pfam00055
Laminin N-terminal (Domain VI);
29-275 3.90e-82

Laminin N-terminal (Domain VI);


Pssm-ID: 459653  Cd Length: 230  Bit Score: 269.45  E-value: 3.90e-82
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   29 LFPAILNLATNAHISANATCGEKGPEMFCKLVEHVPGRpvrhaQCRVCDgnSTNPRERHPITHAIDGTNN----WWQSPS 104
Cdd:pfam00055    1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSGLEGGK-----KCFICD--SRDPHNSHPPSNLTDSNNGtnetWWQSET 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  105 IQngREYHWVTVTLDLRQVFQVAYVIIKAAnAPRPGNWILERSVD-GVKFRPWQYYAvsdTECLTRYKITPRrgPPTYRA 183
Cdd:pfam00055   74 GV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRPSG--PSRGIK 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  184 DNEVICTSYYSKLVPLEHGEIHTSLINGRPSA--DDPSPQLLEFTSARYIRLRLQRIRTLNADLMTlshrdlrdlDPIVT 261
Cdd:pfam00055  146 DDEVICTSEYSDISPLTGGEVIFSTLEGRPSAniFDYSPELQDWLTATNIRIRLLRLHTLGDELLD---------DPSVL 216

                          250
                   ....*....|....
gi 1958802946  262 RRYYYSIKDISVGG 275
Cdd:pfam00055  217 RKYYYAISDISVGG 230
Laminin_B pfam00052
Laminin B (Domain IV);
1225-1367 4.19e-49

Laminin B (Domain IV);


Pssm-ID: 459652  Cd Length: 136  Bit Score: 170.91  E-value: 4.19e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1225 YWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGTGTSNYEPQVLIKGGRTRKHIIYMDAPAPENGVRQDYEVGMKEEFWKYf 1304
Cdd:pfam00052    1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958802946 1305 nsVSEKHVTHSDFMSVLSNIEYILIKASYGQGLQQSRIANISMEVGRkavePAPEGKVALQLE 1367
Cdd:pfam00052   80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV----PGGSGPPASWVE 136
LamB smart00281
Laminin B domain;
572-702 3.99e-46

Laminin B domain;


Pssm-ID: 214597  Cd Length: 127  Bit Score: 162.05  E-value: 3.99e-46
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   572 SPYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTISTRAEGlSLQPYEEYFNVVRLVPEN 651
Cdd:smart00281    3 EPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFREEN 78

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946   652 FRDFNtRREIDRDQLMTVLANVTHLLIRANYnSAKMALYRLDSVSLDIASP 702
Cdd:smart00281   79 WQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
Laminin_B pfam00052
Laminin B (Domain IV);
575-714 8.38e-45

Laminin B (Domain IV);


Pssm-ID: 459652  Cd Length: 136  Bit Score: 158.59  E-value: 8.38e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  575 YWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETvdSNLMSHADVIIKGNGLTISTRAEG-LSLQPYEEYFNVVRLVPENFR 653
Cdd:pfam00052    1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSEPDVILEGNGLRLSYSSPDqPPPDPGQEQTYSVRLHEENWR 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  654 DfNTRREIDRDQLMTVLANVTHLLIRANYNSaKMALYRLDSVSLDIASPNAIDLvVAADVE 714
Cdd:pfam00052   79 D-SDGAPVSREDFMMVLANLTAILIRATYST-GSGQVSLSNVSLDSAVPGGSGP-PASWVE 136
LamB smart00281
Laminin B domain;
1221-1351 4.01e-39

Laminin B domain;


Pssm-ID: 214597  Cd Length: 127  Bit Score: 142.01  E-value: 4.01e-39
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  1221 AEPFYWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGtGTSNYEPQVLIKGGRTRKHIIYMDAPAPENGVRQDYEvgMKEEF 1300
Cdd:smart00281    2 NEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRG-GTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVEVR--FREEN 78

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  1301 WKYFNsvsEKHVTHSDFMSVLSNIEYILIKASYGQGLQQSRIANISMEVGR 1351
Cdd:smart00281   79 WQYYG---GRPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAV 126
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 909-955 2.62e-12

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 62.76  E-value: 2.62e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1958802946  909 CNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDTGLGC 955
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQ 47
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 908-956 2.97e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 59.68  E-value: 2.97e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  908 ACNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDT-GLGCV 956
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
909-955 1.33e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 57.71  E-value: 1.33e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958802946   909 CNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGlDTGLGC 955
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1051-1099 1.76e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946 1051 CNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGYRSFPDCVPCDC 1099
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1516-1553 1.94e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.94e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958802946 1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 404-463 2.08e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 2.08e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  404 CDCDPVGSLSSVCIKddlhadlangkWPGQCPCRKGYAGDKCDRCQFGYRGFPNCVPCDC 463
Cdd:pfam00053    1 CDCNPHGSLSDTCDP-----------ETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1516-1553 2.17e-09

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.67  E-value: 2.17e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958802946 1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:cd00055      2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1516-1553 5.79e-09

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 53.08  E-value: 5.79e-09
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1958802946  1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1410-1456 3.96e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 3.96e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1410 CNCNNH---SDVCDPETGKCLnCRDHTAGDHCELCTAGYYGKVIGLPGDC 1456
Cdd:pfam00053    1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1097-1154 4.59e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 4.59e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958802946 1097 CDCDLRGTLADTCDLEQGlcsctedsgTCSCKENVLGPQCDKCRAGTFALRADNPLGC 1154
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETG---------QCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 461-507 6.28e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.43  E-value: 6.28e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  461 CDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNLKERNPEGC 507
Cdd:pfam00053    1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 958-1005 9.57e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 49.66  E-value: 9.57e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  958 CNCSGEGSISDNCTEE-GQCHCVPGVSGKQCDQCSHGFYAFQNGGCTPC 1005
Cdd:pfam00053    1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
958-1002 1.44e-07

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 49.23  E-value: 1.44e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946   958 CNCSGEGSISDNC-TEEGQCHCVPGVSGKQCDQCSHGFYAFQNGGC 1002
Cdd:smart00180    1 CDCDPGGSASGTCdPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1050-1093 1.55e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 49.27  E-value: 1.55e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958802946 1050 ACNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGYRSFPD 1093
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 403-456 3.51e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 48.12  E-value: 3.51e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958802946  403 PCDCDPVGSLSSVCIKDDlhadlangkwpGQCPCRKGYAGDKCDRCQFGYRGFP 456
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGT-----------GQCECKPNTTGRRCDRCAPGYYGLP 43
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1051-1094 5.84e-07

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 47.69  E-value: 5.84e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946  1051 CNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGY--RSFPDC 1094
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYygDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1409-1447 7.18e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 7.18e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1958802946 1409 PCNCNNHSDV---CDPETGKCLnCRDHTAGDHCELCTAGYYG 1447
Cdd:cd00055      1 PCDCNGHGSLsgqCDPGTGQCE-CKPNTTGRRCDRCAPGYYG 41
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 748-796 7.84e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 7.84e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  748 PCECHGHSS---ECD-IHGICSgCTHNTTGDHCEQCLPGFYGTPSRgtPGDCQ 796
Cdd:cd00055      1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 855-907 8.56e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 8.56e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  855 PCNCSGNVDplEAGHCDSVTGECLkCLWNTDGAHCERCADGFYGDAVTAKNCR 907
Cdd:cd00055      1 PCDCNGHGS--LSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 957-1003 1.05e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 46.96  E-value: 1.05e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  957 PCNCSGEGSISDNCTEE-GQCHCVPGVSGKQCDQCSHGFY--AFQNGGCT 1003
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGtGQCECKPNTTGRRCDRCAPGYYglPSQGGGCQ 50
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 856-902 1.60e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 46.19  E-value: 1.60e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1958802946  856 CNCSGNVDPleAGHCDSVTGECLkCLWNTDGAHCERCADGFYGDAVT 902
Cdd:pfam00053    1 CDCNPHGSL--SDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSD 44
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 460-507 3.16e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.42  E-value: 3.16e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  460 PCDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNLKERnPEGC 507
Cdd:cd00055      1 PCDCNGHGSLSGqcDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQ-GGGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1004-1049 3.32e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.42  E-value: 3.32e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1004 PCDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGLDPE-QGCQ 1049
Cdd:cd00055      1 PCDCnghGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
461-507 6.15e-06

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 44.61  E-value: 6.15e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 1958802946   461 CDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNlkeRNPEGC 507
Cdd:smart00180    1 CDCDPGGSASGtcDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
404-456 8.26e-06

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 44.22  E-value: 8.26e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946   404 CDCDPVGSLSSVCIKDDlhadlangkwpGQCPCRKGYAGDKCDRCQFGYRGFP 456
Cdd:smart00180    1 CDCDPGGSASGTCDPDT-----------GQCECKPNVTGRRCDRCAPGYYGDG 42
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1096-1154 1.22e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 43.88  E-value: 1.22e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802946 1096 PCDCDLRGTLADTCDLEqglcsctedSGTCSCKENVLGPQCDKCRAGTFALrADNPLGC 1154
Cdd:cd00055      1 PCDCNGHGSLSGQCDPG---------TGQCECKPNTTGRRCDRCAPGYYGL-PSQGGGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1005-1048 1.34e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 43.84  E-value: 1.34e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958802946  1005 CDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGlDPEQGC 1048
Cdd:smart00180    1 CDCdpgGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1005-1048 1.80e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 1.80e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946 1005 CDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGL--DPEQGC 1048
Cdd:pfam00053    1 CDCnphGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 749-795 1.93e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 1.93e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  749 CECHGHSS---ECDIH-GICSgCTHNTTGDHCEQCLPGFYGTPSrGTPGDC 795
Cdd:pfam00053    1 CDCNPHGSlsdTCDPEtGQCL-CKPGVTGRHCDRCKPGYYGLPS-DPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 277-324 2.16e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 43.11  E-value: 2.16e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  277 CICSGHAS---SCpwdeEAKQLQCQCEHNTCGESCDRCCPGFHQQPWRPGT 324
Cdd:cd00055      2 CDCNGHGSlsgQC----DPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1097-1154 2.61e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 42.68  E-value: 2.61e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958802946  1097 CDCDLRGTLADTCDLeqglcscteDSGTCSCKENVLGPQCDKCRAGTFalrADNPLGC 1154
Cdd:smart00180    1 CDCDPGGSASGTCDP---------DTGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1410-1448 2.99e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 42.68  E-value: 2.99e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1958802946  1410 CNCN---NHSDVCDPETGKCLnCRDHTAGDHCELCTAGYYGK 1448
Cdd:smart00180    1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 798-853 7.96e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 41.57  E-value: 7.96e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958802946  798 CACPLSIDSnnfSPTChltDREEVVCdQCAPGYSGAWCERCADGYYGNPTVPGGTC 853
Cdd:pfam00053    1 CDCNPHGSL---SDTC---DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
855-899 6.49e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 38.83  E-value: 6.49e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 1958802946   855 PCNCSGNVDPleagHCDSVTGECLkCLWNTDGAHCERCADGFYGD 899
Cdd:smart00180    2 DCDPGGSASG----TCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
749-790 8.99e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 38.45  E-value: 8.99e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946   749 CECHG---HSSECD-IHGICSgCTHNTTGDHCEQCLPGFYGTPSRG 790
Cdd:smart00180    1 CDCDPggsASGTCDpDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1459-1513 9.13e-04

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.49  E-value: 9.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958802946 1459 CTCPHHPpfSFSPTCVLEGdsgFWCDaCLPGYEGQYCERCSAGYHGNPRAAGGSC 1513
Cdd:pfam00053    1 CDCNPHG--SLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 797-851 7.86e-03

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 36.18  E-value: 7.86e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958802946  797 PCACPLSIDSNnfsPTChltDREEVVCdQCAPGYSGAWCERCADGYYGNPTVPGG 851
Cdd:cd00055      1 PCDCNGHGSLS---GQC---DPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGGG 48
 
Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
 25-275 7.52e-91

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


Pssm-ID: 214532  Cd Length: 238  Bit Score: 294.65  E-value: 7.52e-91
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946    25 QQRGLFPAILNLATNAHISANATCGEKGPEMFCKLVehvpGRPVRHAQCRVCDgnSTNPRERHPITHAIDGTN----NWW 100
Cdd:smart00136    3 RPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCD--ARNPRRSHPAENLTDGNNpnnpTWW 76

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   101 QSPSIQNGReyHWVTVTLDLRQVFQVAYVIIKAAnAPRPGNWILERSVDGVKFRPWQYYAvsdTECLTRYKITPRRGPPT 180
Cdd:smart00136   77 QSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPITK 150

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   181 YrADNEVICTSYYSKLVPLEHGEIHTSLINGRPSADDP--SPQLLEFTSARYIRLRLQRIRTLNADLMtlshrdlrDLDP 258
Cdd:smart00136  151 G-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELM--------DDRP 221

                           250
                    ....*....|....*..
gi 1958802946   259 IVTRRYYYSIKDISVGG 275
Cdd:smart00136  222 EVTRRYYYAISDIAVGG 238
Laminin_N pfam00055
Laminin N-terminal (Domain VI);
29-275 3.90e-82

Laminin N-terminal (Domain VI);


Pssm-ID: 459653  Cd Length: 230  Bit Score: 269.45  E-value: 3.90e-82
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   29 LFPAILNLATNAHISANATCGEKGPEMFCKLVEHVPGRpvrhaQCRVCDgnSTNPRERHPITHAIDGTNN----WWQSPS 104
Cdd:pfam00055    1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSGLEGGK-----KCFICD--SRDPHNSHPPSNLTDSNNGtnetWWQSET 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  105 IQngREYHWVTVTLDLRQVFQVAYVIIKAAnAPRPGNWILERSVD-GVKFRPWQYYAvsdTECLTRYKITPRrgPPTYRA 183
Cdd:pfam00055   74 GV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRPSG--PSRGIK 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  184 DNEVICTSYYSKLVPLEHGEIHTSLINGRPSA--DDPSPQLLEFTSARYIRLRLQRIRTLNADLMTlshrdlrdlDPIVT 261
Cdd:pfam00055  146 DDEVICTSEYSDISPLTGGEVIFSTLEGRPSAniFDYSPELQDWLTATNIRIRLLRLHTLGDELLD---------DPSVL 216

                          250
                   ....*....|....
gi 1958802946  262 RRYYYSIKDISVGG 275
Cdd:pfam00055  217 RKYYYAISDISVGG 230
Laminin_B pfam00052
Laminin B (Domain IV);
1225-1367 4.19e-49

Laminin B (Domain IV);


Pssm-ID: 459652  Cd Length: 136  Bit Score: 170.91  E-value: 4.19e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1225 YWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGTGTSNYEPQVLIKGGRTRKHIIYMDAPAPENGVRQDYEVGMKEEFWKYf 1304
Cdd:pfam00052    1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958802946 1305 nsVSEKHVTHSDFMSVLSNIEYILIKASYGQGLQQSRIANISMEVGRkavePAPEGKVALQLE 1367
Cdd:pfam00052   80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV----PGGSGPPASWVE 136
LamB smart00281
Laminin B domain;
572-702 3.99e-46

Laminin B domain;


Pssm-ID: 214597  Cd Length: 127  Bit Score: 162.05  E-value: 3.99e-46
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946   572 SPYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTISTRAEGlSLQPYEEYFNVVRLVPEN 651
Cdd:smart00281    3 EPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFREEN 78

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946   652 FRDFNtRREIDRDQLMTVLANVTHLLIRANYnSAKMALYRLDSVSLDIASP 702
Cdd:smart00281   79 WQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
Laminin_B pfam00052
Laminin B (Domain IV);
575-714 8.38e-45

Laminin B (Domain IV);


Pssm-ID: 459652  Cd Length: 136  Bit Score: 158.59  E-value: 8.38e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  575 YWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETvdSNLMSHADVIIKGNGLTISTRAEG-LSLQPYEEYFNVVRLVPENFR 653
Cdd:pfam00052    1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSEPDVILEGNGLRLSYSSPDqPPPDPGQEQTYSVRLHEENWR 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  654 DfNTRREIDRDQLMTVLANVTHLLIRANYNSaKMALYRLDSVSLDIASPNAIDLvVAADVE 714
Cdd:pfam00052   79 D-SDGAPVSREDFMMVLANLTAILIRATYST-GSGQVSLSNVSLDSAVPGGSGP-PASWVE 136
LamB smart00281
Laminin B domain;
1221-1351 4.01e-39

Laminin B domain;


Pssm-ID: 214597  Cd Length: 127  Bit Score: 142.01  E-value: 4.01e-39
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  1221 AEPFYWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGtGTSNYEPQVLIKGGRTRKHIIYMDAPAPENGVRQDYEvgMKEEF 1300
Cdd:smart00281    2 NEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRG-GTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVEVR--FREEN 78

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  1301 WKYFNsvsEKHVTHSDFMSVLSNIEYILIKASYGQGLQQSRIANISMEVGR 1351
Cdd:smart00281   79 WQYYG---GRPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAV 126
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 909-955 2.62e-12

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 62.76  E-value: 2.62e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1958802946  909 CNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDTGLGC 955
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQ 47
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 908-956 2.97e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 59.68  E-value: 2.97e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  908 ACNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDT-GLGCV 956
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
909-955 1.33e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 57.71  E-value: 1.33e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958802946   909 CNCHENGSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGlDTGLGC 955
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1051-1099 1.76e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946 1051 CNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGYRSFPDCVPCDC 1099
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1516-1553 1.94e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 1.94e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958802946 1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 404-463 2.08e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 2.08e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802946  404 CDCDPVGSLSSVCIKddlhadlangkWPGQCPCRKGYAGDKCDRCQFGYRGFPNCVPCDC 463
Cdd:pfam00053    1 CDCNPHGSLSDTCDP-----------ETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1516-1553 2.17e-09

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.67  E-value: 2.17e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1958802946 1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:cd00055      2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1516-1553 5.79e-09

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 53.08  E-value: 5.79e-09
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1958802946  1516 CDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPRH 1553
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1410-1456 3.96e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 3.96e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1410 CNCNNH---SDVCDPETGKCLnCRDHTAGDHCELCTAGYYGKVIGLPGDC 1456
Cdd:pfam00053    1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1097-1154 4.59e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.81  E-value: 4.59e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958802946 1097 CDCDLRGTLADTCDLEQGlcsctedsgTCSCKENVLGPQCDKCRAGTFALRADNPLGC 1154
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETG---------QCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 461-507 6.28e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 50.43  E-value: 6.28e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  461 CDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNLKERNPEGC 507
Cdd:pfam00053    1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 958-1005 9.57e-08

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 49.66  E-value: 9.57e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946  958 CNCSGEGSISDNCTEE-GQCHCVPGVSGKQCDQCSHGFYAFQNGGCTPC 1005
Cdd:pfam00053    1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
958-1002 1.44e-07

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 49.23  E-value: 1.44e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946   958 CNCSGEGSISDNC-TEEGQCHCVPGVSGKQCDQCSHGFYAFQNGGC 1002
Cdd:smart00180    1 CDCDPGGSASGTCdPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1050-1093 1.55e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 49.27  E-value: 1.55e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1958802946 1050 ACNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGYRSFPD 1093
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 403-456 3.51e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 48.12  E-value: 3.51e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958802946  403 PCDCDPVGSLSSVCIKDDlhadlangkwpGQCPCRKGYAGDKCDRCQFGYRGFP 456
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGT-----------GQCECKPNTTGRRCDRCAPGYYGLP 43
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1051-1094 5.84e-07

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 47.69  E-value: 5.84e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946  1051 CNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGY--RSFPDC 1094
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYygDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1409-1447 7.18e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 7.18e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1958802946 1409 PCNCNNHSDV---CDPETGKCLnCRDHTAGDHCELCTAGYYG 1447
Cdd:cd00055      1 PCDCNGHGSLsgqCDPGTGQCE-CKPNTTGRRCDRCAPGYYG 41
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 748-796 7.84e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 7.84e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  748 PCECHGHSS---ECD-IHGICSgCTHNTTGDHCEQCLPGFYGTPSRgtPGDCQ 796
Cdd:cd00055      1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 855-907 8.56e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 47.35  E-value: 8.56e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946  855 PCNCSGNVDplEAGHCDSVTGECLkCLWNTDGAHCERCADGFYGDAVTAKNCR 907
Cdd:cd00055      1 PCDCNGHGS--LSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 957-1003 1.05e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 46.96  E-value: 1.05e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  957 PCNCSGEGSISDNCTEE-GQCHCVPGVSGKQCDQCSHGFY--AFQNGGCT 1003
Cdd:cd00055      1 PCDCNGHGSLSGQCDPGtGQCECKPNTTGRRCDRCAPGYYglPSQGGGCQ 50
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 856-902 1.60e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 46.19  E-value: 1.60e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1958802946  856 CNCSGNVDPleAGHCDSVTGECLkCLWNTDGAHCERCADGFYGDAVT 902
Cdd:pfam00053    1 CDCNPHGSL--SDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSD 44
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 460-507 3.16e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.42  E-value: 3.16e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946  460 PCDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNLKERnPEGC 507
Cdd:cd00055      1 PCDCNGHGSLSGqcDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQ-GGGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1004-1049 3.32e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.42  E-value: 3.32e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958802946 1004 PCDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGLDPE-QGCQ 1049
Cdd:cd00055      1 PCDCnghGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
461-507 6.15e-06

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 44.61  E-value: 6.15e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 1958802946   461 CDCSTVGSVNE--DPCTEPCLCKKNVEGENCDRCKPGFYNlkeRNPEGC 507
Cdd:smart00180    1 CDCDPGGSASGtcDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
404-456 8.26e-06

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 44.22  E-value: 8.26e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1958802946   404 CDCDPVGSLSSVCIKDDlhadlangkwpGQCPCRKGYAGDKCDRCQFGYRGFP 456
Cdd:smart00180    1 CDCDPGGSASGTCDPDT-----------GQCECKPNVTGRRCDRCAPGYYGDG 42
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 1096-1154 1.22e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 43.88  E-value: 1.22e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802946 1096 PCDCDLRGTLADTCDLEqglcsctedSGTCSCKENVLGPQCDKCRAGTFALrADNPLGC 1154
Cdd:cd00055      1 PCDCNGHGSLSGQCDPG---------TGQCECKPNTTGRRCDRCAPGYYGL-PSQGGGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1005-1048 1.34e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 43.84  E-value: 1.34e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1958802946  1005 CDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGlDPEQGC 1048
Cdd:smart00180    1 CDCdpgGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1005-1048 1.80e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 1.80e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958802946 1005 CDC---AHTQNNCDPDSGECLCPPHTHGLKCEQCEEAFWGL--DPEQGC 1048
Cdd:pfam00053    1 CDCnphGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 749-795 1.93e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 1.93e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  749 CECHGHSS---ECDIH-GICSgCTHNTTGDHCEQCLPGFYGTPSrGTPGDC 795
Cdd:pfam00053    1 CDCNPHGSlsdTCDPEtGQCL-CKPGVTGRHCDRCKPGYYGLPS-DPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 277-324 2.16e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 43.11  E-value: 2.16e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958802946  277 CICSGHAS---SCpwdeEAKQLQCQCEHNTCGESCDRCCPGFHQQPWRPGT 324
Cdd:cd00055      2 CDCNGHGSlsgQC----DPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1097-1154 2.61e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 42.68  E-value: 2.61e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958802946  1097 CDCDLRGTLADTCDLeqglcscteDSGTCSCKENVLGPQCDKCRAGTFalrADNPLGC 1154
Cdd:smart00180    1 CDCDPGGSASGTCDP---------DTGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
1410-1448 2.99e-05

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 42.68  E-value: 2.99e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1958802946  1410 CNCN---NHSDVCDPETGKCLnCRDHTAGDHCELCTAGYYGK 1448
Cdd:smart00180    1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 798-853 7.96e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 41.57  E-value: 7.96e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958802946  798 CACPLSIDSnnfSPTChltDREEVVCdQCAPGYSGAWCERCADGYYGNPTVPGGTC 853
Cdd:pfam00053    1 CDCNPHGSL---SDTC---DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
855-899 6.49e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 38.83  E-value: 6.49e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 1958802946   855 PCNCSGNVDPleagHCDSVTGECLkCLWNTDGAHCERCADGFYGD 899
Cdd:smart00180    2 DCDPGGSASG----TCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
749-790 8.99e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 38.45  E-value: 8.99e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1958802946   749 CECHG---HSSECD-IHGICSgCTHNTTGDHCEQCLPGFYGTPSRG 790
Cdd:smart00180    1 CDCDPggsASGTCDpDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 1459-1513 9.13e-04

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.49  E-value: 9.13e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958802946 1459 CTCPHHPpfSFSPTCVLEGdsgFWCDaCLPGYEGQYCERCSAGYHGNPRAAGGSC 1513
Cdd:pfam00053    1 CDCNPHG--SLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 797-851 7.86e-03

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 36.18  E-value: 7.86e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958802946  797 PCACPLSIDSNnfsPTChltDREEVVCdQCAPGYSGAWCERCADGYYGNPTVPGG 851
Cdd:cd00055      1 PCDCNGHGSLS---GQC---DPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGGG 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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