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Conserved domains on  [gi|1958790945|ref|XP_038935655|]
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zinc finger protein 799 isoform X3 [Rattus norvegicus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
214-602 1.97e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 214 KPYTCKQCGKTFARSSSLLTHERIHTGEKPYVC--KQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHE 291
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 292 RTHTGEQlFVCLQCEKVFSCESAFRTHK----IIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPyvckqcGKTFRSPK 367
Cdd:COG5048   112 SSSSNSN-DNNLLSSHSLPPSSRDPQLPdllsISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL------SKDPSSNL 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 368 QVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYVCKQCGKAF 447
Cdd:COG5048   185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 448 FSLYHLRRHEVIHSG-------TNPYVCKQCGKAFSWFSTFHSHKQT--HTGE--KPYLC--KQCGKAFCSRISWRRHEK 514
Cdd:COG5048   265 LPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHIL 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 515 AHTTVKPYACV--QCGKAFRSPSYLKIHERIH-----TGEKPFIC--SQCGKPFRSFRYVKSHERSHTGEKP--FVCTEC 583
Cdd:COG5048   345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPC 424

                         410
                  ....*....|....*....
gi 1958790945 584 GKAFSYYSSFHRHRRTHQT 602
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTN 443
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
214-602 1.97e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 214 KPYTCKQCGKTFARSSSLLTHERIHTGEKPYVC--KQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHE 291
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 292 RTHTGEQlFVCLQCEKVFSCESAFRTHK----IIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPyvckqcGKTFRSPK 367
Cdd:COG5048   112 SSSSNSN-DNNLLSSHSLPPSSRDPQLPdllsISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL------SKDPSSNL 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 368 QVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYVCKQCGKAF 447
Cdd:COG5048   185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 448 FSLYHLRRHEVIHSG-------TNPYVCKQCGKAFSWFSTFHSHKQT--HTGE--KPYLC--KQCGKAFCSRISWRRHEK 514
Cdd:COG5048   265 LPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHIL 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 515 AHTTVKPYACV--QCGKAFRSPSYLKIHERIH-----TGEKPFIC--SQCGKPFRSFRYVKSHERSHTGEKP--FVCTEC 583
Cdd:COG5048   345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPC 424

                         410
                  ....*....|....*....
gi 1958790945 584 GKAFSYYSSFHRHRRTHQT 602
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTN 443
zf-H2C2_2 pfam13465
Zinc-finger double domain;
202-227 1.48e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.48e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958790945 202 SLQIHERIHTGEKPYTCKQCGKTFAR 227
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
214-602 1.97e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 214 KPYTCKQCGKTFARSSSLLTHERIHTGEKPYVC--KQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHE 291
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 292 RTHTGEQlFVCLQCEKVFSCESAFRTHK----IIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPyvckqcGKTFRSPK 367
Cdd:COG5048   112 SSSSNSN-DNNLLSSHSLPPSSRDPQLPdllsISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL------SKDPSSNL 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 368 QVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYVCKQCGKAF 447
Cdd:COG5048   185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 448 FSLYHLRRHEVIHSG-------TNPYVCKQCGKAFSWFSTFHSHKQT--HTGE--KPYLC--KQCGKAFCSRISWRRHEK 514
Cdd:COG5048   265 LPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHIL 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 515 AHTTVKPYACV--QCGKAFRSPSYLKIHERIH-----TGEKPFIC--SQCGKPFRSFRYVKSHERSHTGEKP--FVCTEC 583
Cdd:COG5048   345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPC 424

                         410
                  ....*....|....*....
gi 1958790945 584 GKAFSYYSSFHRHRRTHQT 602
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTN 443
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
188-569 4.31e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 4.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 188 YVCKQCGKAFPFPSSLQIHERIHTGEKPYTC--KQCGKTFARSSSLLTHERIHTGEKPYVCKQCGK--AFTDRSSLRFHE 263
Cdd:COG5048    34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPlsNSKASSSSLSSS 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 264 MMHSgEKPYKCTKCGKAFASSGAFRKHERTHTGEQLFVCLQC-EKVFSCESAFRTHkIIHSGECVCKQCGKAFTSHSSvk 342
Cdd:COG5048   114 SSNS-NDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnSSSVNTPQSNSLH-PPLPANSLSKDPSSNLSLLIS-- 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 343 yHELMHSGEKPYVCKQCGKTFRSPKQVQIHKRTH-TGEKPYVCKECGKAFTFLGSLQYHE----LIHTGEKPYLCKQCGK 417
Cdd:COG5048   190 -SNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENsSSSLPLTTNSQLSPKSLLSQSPSSLsssdSSSSASESPRSSLPTA 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 418 AFRSSRQVQIHERTHTG-EKPYVCKQCGKAFFSLYHLRRH--EVIHSG--TNPYVC--KQCGKAFSWFSTFHSHKQTHTG 490
Cdd:COG5048   269 SSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHlrSVNHSGesLKPFSCpySLCGKLFSRNDALKRHILLHTS 348

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 491 EKPYLCK--QCGK------------------------------AFCSRISWRR-----HEKAHTTVKPYAC--VQCGKAF 531
Cdd:COG5048   349 ISPAKEKllNSSSkfspllnneppqslqqykdlkndkksetlsNSCIRNFKRDsnlslHIITHLSFRPYNCknPPCSKSF 428

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 1958790945 532 RSPSYLKIHERIHTGEKPFICSQCGKPFRSFRYVKSHE 569
Cdd:COG5048   429 NRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 326-400 9.39e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 9.39e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958790945 326 CVCKQCGKAFTSHSSVKYHELM-HsgekpyvCKQCGKTFRSPKQVQIHKrthTGEKPYVCKECGKAFTFLGSLQYH 400
Cdd:COG5189   352 CPVEGCNKKYKNQNGLKYHMLHgH-------QNQKLHENPSPEKMNIFS---AKDKPYRCEVCDKRYKNLNGLKYH 417
zf-H2C2_2 pfam13465
Zinc-finger double domain;
202-227 1.48e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.48e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958790945 202 SLQIHERIHTGEKPYTCKQCGKTFAR 227
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
564-589 2.89e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 2.89e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958790945 564 YVKSHERSHTGEKPFVCTECGKAFSY 589
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
230-254 4.32e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 4.32e-03
                          10        20
                  ....*....|....*....|....*
gi 1958790945 230 SLLTHERIHTGEKPYVCKQCGKAFT 254
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
110-486 5.61e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.68  E-value: 5.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 110 SGSTSNPSTPFQKQrrvhAEEKPETSHCKEDSR---CLIFSHNDDRTSSGEQHYEC--KQCGKVFTSASSFRRHEEYHSR 184
Cdd:COG5048    13 NSVLSSTPKSTLKS----LSNAPRPDSCPNCTDsfsRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 185 EKAYVC-KQCGKAFPFPSSLQIHERIHTGEKPYTCKQCGKTFARSSSLLTHERIHTGEKPYVCKQCGKAFTDR-----SS 258
Cdd:COG5048    89 NPSDLNsKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnsLH 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 259 LRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHERTHT------------------------GEQLFVC----LQCEKVFS 310
Cdd:COG5048   169 PPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLsssysipssssdqnlensssslplTTNSQLSpkslLSQSPSSL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 311 CESAFRTHKIIHSGECVCKqcgKAFTSHSSVKYHELMHSG-EKPYVCKQCGKTFRSPKQVQIHKRT--HTGE--KPYVCK 385
Cdd:COG5048   249 SSSDSSSSASESPRSSLPT---ASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCP 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958790945 386 E--CGKAFTFLGSLQYHELIHTGEKPYLCK-------------------------------------QCGKAFRSSRQVQ 426
Cdd:COG5048   326 YslCGKLFSRNDALKRHILLHTSISPAKEKllnssskfspllnneppqslqqykdlkndkksetlsnSCIRNFKRDSNLS 405

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958790945 427 IHERTHTGEKPYVCK--QCGKAFFSLYHLRRHEVIHSGTNPYVCKQCGKAFSWFSTFHSHKQ 486
Cdd:COG5048   406 LHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
zf-H2C2_2 pfam13465
Zinc-finger double domain;
372-392 6.99e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 6.99e-03
                          10        20
                  ....*....|....*....|.
gi 1958790945 372 HKRTHTGEKPYVCKECGKAFT 392
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
258-283 7.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 7.06e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958790945 258 SLRFHEMMHSGEKPYKCTKCGKAFAS 283
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
396-421 7.27e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 7.27e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958790945 396 SLQYHELIHTGEKPYLCKQCGKAFRS 421
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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