NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958646304|ref|XP_038934937|]
View 

mitochondrial glutamate carrier 1 isoform X2 [Rattus norvegicus]

Protein Classification

solute carrier family 25 protein( domain architecture ID 13506698)

solute carrier 25 family (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0016020|GO:1990542
TCDB:  2.A.29

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
4-98 3.61e-23

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 91.56  E-value: 3.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ-QNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAI 82
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQgGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|....*.
gi 1958646304  83 KLAANDFFRHQLSKDG 98
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
3-289 1.24e-15

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 75.96  E-value: 1.24e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ------QNGQ-RMYASMSDCLIKTIRSEGYFGMYRGAAVNLTL 75
Cdd:PTZ00169    2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQdsipeiKSGKvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  76 VTPEKAIKLAANDFFRHQLSKDGQKLTLPK----EMLAGCGAGTCQVIVTTPMEMlkiqlqdagriaaqrkmlaAQAQLA 151
Cdd:PTZ00169   82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDF-------------------ARTRLA 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 152 TQGGGQPSVEApaaprptaTQLTRDLL---RNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFY-- 226
Cdd:PTZ00169  143 SDIGKGGDREF--------TGLFDCLMkisKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYkw 214
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 227 -----VSFLAGCVAGsaaavavnPCDVVKTRLQ--SLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAY 289
Cdd:PTZ00169  215 avaqtVTILAGLISY--------PFDTVRRRMMmmSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAW 276
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
4-98 3.61e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 91.56  E-value: 3.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ-QNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAI 82
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQgGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|....*.
gi 1958646304  83 KLAANDFFRHQLSKDG 98
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
3-289 1.24e-15

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 75.96  E-value: 1.24e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ------QNGQ-RMYASMSDCLIKTIRSEGYFGMYRGAAVNLTL 75
Cdd:PTZ00169    2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQdsipeiKSGKvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  76 VTPEKAIKLAANDFFRHQLSKDGQKLTLPK----EMLAGCGAGTCQVIVTTPMEMlkiqlqdagriaaqrkmlaAQAQLA 151
Cdd:PTZ00169   82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDF-------------------ARTRLA 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 152 TQGGGQPSVEApaaprptaTQLTRDLL---RNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFY-- 226
Cdd:PTZ00169  143 SDIGKGGDREF--------TGLFDCLMkisKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYkw 214
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 227 -----VSFLAGCVAGsaaavavnPCDVVKTRLQ--SLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAY 289
Cdd:PTZ00169  215 avaqtVTILAGLISY--------PFDTVRRRMMmmSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAW 276
Mito_carr pfam00153
Mitochondrial carrier protein;
99-208 2.57e-14

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 67.68  E-value: 2.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  99 QKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKMLAAQAqlatqgggqpsveapaaprptatqlTRDLL 178
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDC-------------------------FKKIY 55
                          90       100       110
                  ....*....|....*....|....*....|
gi 1958646304 179 RNHGIAGLYKGLGATLLRDVPFSIVYFPLF 208
Cdd:pfam00153  56 KEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
4-98 3.61e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 91.56  E-value: 3.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ-QNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAI 82
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQgGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|....*.
gi 1958646304  83 KLAANDFFRHQLSKDG 98
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
3-289 1.24e-15

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 75.96  E-value: 1.24e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304   3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQ------QNGQ-RMYASMSDCLIKTIRSEGYFGMYRGAAVNLTL 75
Cdd:PTZ00169    2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQdsipeiKSGKvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  76 VTPEKAIKLAANDFFRHQLSKDGQKLTLPK----EMLAGCGAGTCQVIVTTPMEMlkiqlqdagriaaqrkmlaAQAQLA 151
Cdd:PTZ00169   82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDF-------------------ARTRLA 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 152 TQGGGQPSVEApaaprptaTQLTRDLL---RNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFY-- 226
Cdd:PTZ00169  143 SDIGKGGDREF--------TGLFDCLMkisKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYkw 214
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 227 -----VSFLAGCVAGsaaavavnPCDVVKTRLQ--SLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAY 289
Cdd:PTZ00169  215 avaqtVTILAGLISY--------PFDTVRRRMMmmSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAW 276
Mito_carr pfam00153
Mitochondrial carrier protein;
99-208 2.57e-14

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 67.68  E-value: 2.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  99 QKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKMLAAQAqlatqgggqpsveapaaprptatqlTRDLL 178
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDC-------------------------FKKIY 55
                          90       100       110
                  ....*....|....*....|....*....|
gi 1958646304 179 RNHGIAGLYKGLGATLLRDVPFSIVYFPLF 208
Cdd:pfam00153  56 KEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
221-306 6.88e-13

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 63.83  E-value: 6.88e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 221 EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSlERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFG 300
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQV-QGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAA 79

                  ....*.
gi 1958646304 301 IAQVVY 306
Cdd:pfam00153  80 IYFGTY 85
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
12-300 5.73e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 40.68  E-value: 5.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  12 LINGGIAGLIGVTCVFPIDLAKTRLQNQQ-----NGQRMYASMSDCLIKTIRSEGYFGMYRgaavnltlvtpEKAIKLAA 86
Cdd:PTZ00168    7 LVTGALSGVIVDAVLYPIDSIKTNIQAKKsfsfsDIKKLYSGILPTLVGTVPASAFFYCFY-----------ELSKKLLT 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304  87 NdfFRHQLSKdgQKLTLPKEMLAGCGAgtcqVIVTTPMEMLKIQLQDAGRIAAQRKMLAAqaqlaTQGGGQPSVeapaap 166
Cdd:PTZ00168   76 E--YRENISK--TNLYLISTSIAEITA----CIVRLPFEIVKQNMQVSGNISVLKTIYEI-----TQREGLPSF------ 136
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958646304 167 rptatqltrdllrnhgiagLYKGLGATLLRDVPFSIVYFPLFANLNQLGRP---SSEEKSPFYVSFLAGCVAGSAAAVAV 243
Cdd:PTZ00168  137 -------------------LGKSYFVMIVREIPFDCIQYFLWETLKEKAKKdfgKFSKKYPSITSAICGGLAGGIAGFLT 197
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958646304 244 NPCDVVKTRL----QSLERGVNEDTYSGFLdcarkiwrhegpsAFLKGAYCRALVIapLFG 300
Cdd:PTZ00168  198 TPVDVIKSRQiiygKSYIETVTEIAEEGYL-------------TFYKGCCFRSSYL--FFG 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH