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Conserved domains on  [gi|1949617176|ref|XP_038120071|]
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uncharacterized protein LOC6031304 isoform X1 [Culex quinquefasciatus]

Protein Classification

TMEM200 family protein( domain architecture ID 8052)

TMEM200 family protein is a DUF2371 domain-containing protein; similar to Homo sapiens transmembrane protein 200B

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2371 super family cl10871
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 33-139 9.53e-13

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


The actual alignment was detected with superfamily member pfam10177:

Pssm-ID: 462979  Cd Length: 141  Bit Score: 66.19  E-value: 9.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949617176  33 VQVVRGKMtsRCLWHACRALVLGIVLMMVGGGMATVGY-YANNFPSLSDVKSNSTTTVRVKNEHRG---------LHLNN 102
Cdd:pfam10177  27 VVVVKGKL--RLCSPSGFFALLGILVLLVGIAMAVLGYwPHEVAQLGSRNNNSSNSTAEMSRDHSGflarfleqyLHSDK 104

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1949617176 103 LSYVGPIIMGVGGFIVVASCVMTFEARDSAAKVVPAR 139
Cdd:pfam10177 105 MKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 33-139 9.53e-13

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 66.19  E-value: 9.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949617176  33 VQVVRGKMtsRCLWHACRALVLGIVLMMVGGGMATVGY-YANNFPSLSDVKSNSTTTVRVKNEHRG---------LHLNN 102
Cdd:pfam10177  27 VVVVKGKL--RLCSPSGFFALLGILVLLVGIAMAVLGYwPHEVAQLGSRNNNSSNSTAEMSRDHSGflarfleqyLHSDK 104

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1949617176 103 LSYVGPIIMGVGGFIVVASCVMTFEARDSAAKVVPAR 139
Cdd:pfam10177 105 MKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 33-139 9.53e-13

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 66.19  E-value: 9.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949617176  33 VQVVRGKMtsRCLWHACRALVLGIVLMMVGGGMATVGY-YANNFPSLSDVKSNSTTTVRVKNEHRG---------LHLNN 102
Cdd:pfam10177  27 VVVVKGKL--RLCSPSGFFALLGILVLLVGIAMAVLGYwPHEVAQLGSRNNNSSNSTAEMSRDHSGflarfleqyLHSDK 104

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1949617176 103 LSYVGPIIMGVGGFIVVASCVMTFEARDSAAKVVPAR 139
Cdd:pfam10177 105 MKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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