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Conserved domains on  [gi|1907161034|ref|XP_036020775|]
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mismatch repair endonuclease PMS2 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
84-278 4.35e-44

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.51  E-value: 4.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  84 ESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGsiyynqegtswyegDWVYNIKKGWGIRCY 163
Cdd:COG4642   102 GGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEG--------------EFKNGKPHGQGTLTY 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 164 KSGNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGTHTWflkriPNSQYplrneYIGEFVNGFRHGQGKFYY 243
Cdd:COG4642   168 ADGDRYEGEFKNGKRHGQGTLTY-ANGDVYEGEFKNGQRHGQGTYTY-----ADGDR-----YEGEFKNGKRHGQGTLTY 236

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1907161034 244 ASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSN 278
Cdd:COG4642   237 ADGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWKN 271
vATP-synt_E super family cl23750
ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as ...
 724-771 1.20e-03

ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as well as the archaebacterial ATP synthase E subunit.


The actual alignment was detected with superfamily member pfam01991:

Pssm-ID: 419987 [Multi-domain]  Cd Length: 199  Bit Score: 40.83  E-value: 1.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907161034 724 AYKREEMLKEKVKENQLQEAELAQQRQIENEELEARLNIL--REE-------EARKQ 771
Cdd:pfam01991  28 LVQEAEEKIDEIYEKKEKQAEMQKKIIISNAKNEARLKVLeaREEildevfnEAEKK 84
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
84-278 4.35e-44

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.51  E-value: 4.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  84 ESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGsiyynqegtswyegDWVYNIKKGWGIRCY 163
Cdd:COG4642   102 GGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEG--------------EFKNGKPHGQGTLTY 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 164 KSGNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGTHTWflkriPNSQYplrneYIGEFVNGFRHGQGKFYY 243
Cdd:COG4642   168 ADGDRYEGEFKNGKRHGQGTLTY-ANGDVYEGEFKNGQRHGQGTYTY-----ADGDR-----YEGEFKNGKRHGQGTLTY 236

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1907161034 244 ASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSN 278
Cdd:COG4642   237 ADGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 86-262 8.59e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 116.86  E-value: 8.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  86 YEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGSiyynqegtswyegdWVYNIKKGWGIRCYKS 165
Cdd:PLN03185   34 YEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGR--------------WRLNLKHGLGYQRYPN 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 166 GNIYEGQWENNMRHGEGRMRWLTTNeEYTGHWEKGIQNGFGTHTWFLKripnsqyplrNEYIGEFVNGFRHGQGKFYYAS 245
Cdd:PLN03185  100 GDVFEGSWIQGLQEGPGKYTWANGN-VYLGDMKGGKMSGKGTLTWVSG----------DSYEGQWLDGMMHGFGVYTWSD 168

                         170
                  ....*....|....*..
gi 1907161034 246 GAMYEGEWASNKKQGRG 262
Cdd:PLN03185  169 GGCYVGTWTRGLKDGKG 185
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
167-186 2.96e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 41.17  E-value: 2.96e-05
                           10        20
                   ....*....|....*....|
gi 1907161034  167 NIYEGQWENNMRHGEGRMRW 186
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 226-248 3.30e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 41.24  E-value: 3.30e-05
                          10        20
                  ....*....|....*....|...
gi 1907161034 226 YIGEFVNGFRHGQGKFYYASGAM 248
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
vATP-synt_E pfam01991
ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as ...
 724-771 1.20e-03

ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as well as the archaebacterial ATP synthase E subunit.


Pssm-ID: 396537 [Multi-domain]  Cd Length: 199  Bit Score: 40.83  E-value: 1.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907161034 724 AYKREEMLKEKVKENQLQEAELAQQRQIENEELEARLNIL--REE-------EARKQ 771
Cdd:pfam01991  28 LVQEAEEKIDEIYEKKEKQAEMQKKIIISNAKNEARLKVLeaREEildevfnEAEKK 84
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
84-278 4.35e-44

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 160.51  E-value: 4.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  84 ESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGsiyynqegtswyegDWVYNIKKGWGIRCY 163
Cdd:COG4642   102 GGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEG--------------EFKNGKPHGQGTLTY 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 164 KSGNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGTHTWflkriPNSQYplrneYIGEFVNGFRHGQGKFYY 243
Cdd:COG4642   168 ADGDRYEGEFKNGKRHGQGTLTY-ANGDVYEGEFKNGQRHGQGTYTY-----ADGDR-----YEGEFKNGKRHGQGTLTY 236

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1907161034 244 ASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSN 278
Cdd:COG4642   237 ADGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-281 6.45e-40

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 148.57  E-value: 6.45e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  86 YEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGsiYYNQEGTSWYEGDWVYNIKKGWGIRCYKS 165
Cdd:COG4642    69 EGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGG--VLEGDDGGGYGGGTADGGRGGGGIYTFPN 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 166 GNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGTHTWflkriPNSqyplrNEYIGEFVNGFRHGQGKFYYAS 245
Cdd:COG4642   147 GDVYEGEFKNGKPHGQGTLTY-ADGDRYEGEFKNGKRHGQGTLTY-----ANG-----DVYEGEFKNGQRHGQGTYTYAD 215

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907161034 246 GAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSNDHI 281
Cdd:COG4642   216 GDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 86-262 8.59e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 116.86  E-value: 8.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  86 YEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGSiyynqegtswyegdWVYNIKKGWGIRCYKS 165
Cdd:PLN03185   34 YEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGR--------------WRLNLKHGLGYQRYPN 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 166 GNIYEGQWENNMRHGEGRMRWLTTNeEYTGHWEKGIQNGFGTHTWFLKripnsqyplrNEYIGEFVNGFRHGQGKFYYAS 245
Cdd:PLN03185  100 GDVFEGSWIQGLQEGPGKYTWANGN-VYLGDMKGGKMSGKGTLTWVSG----------DSYEGQWLDGMMHGFGVYTWSD 168

                         170
                  ....*....|....*..
gi 1907161034 246 GAMYEGEWASNKKQGRG 262
Cdd:PLN03185  169 GGCYVGTWTRGLKDGKG 185
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-280 2.55e-25

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 106.19  E-value: 2.55e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  86 YEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGSIYYNQEGTswYEGDWVYNIKKGWGIRCYKS 165
Cdd:COG4642    11 GGGDATALGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGG--EGGVTAAGGGGGGGGGKGDG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 166 GNIYEGQWENNMRHGEGRmrwLTTNEEYTGHWEKGIQNGFGTHTWFLKRIPNSQ----YPLRNEYIGEFVNGFRHGQGKF 241
Cdd:COG4642    89 GDGGGGEGGFGGGGGGGG---GKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGgiytFPNGDVYEGEFKNGKPHGQGTL 165

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1907161034 242 YYASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSNDH 280
Cdd:COG4642   166 TYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQ 204
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 146-274 4.82e-17

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 85.66  E-value: 4.82e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 146 YEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGTHT----------WFLKR- 214
Cdd:PLN03185   11 YSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISW-PSGATYEGEFSGGYMHGSGTYTgtdgttykgrWRLNLk 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907161034 215 --IPNSQYPLRNEYIGEFVNGFRHGQGKFYYASGAMYEGEWASNKKQGRGRMTFKNGHVYEG 274
Cdd:PLN03185   90 hgLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEG 151
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 85-207 1.11e-11

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 68.71  E-value: 1.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034  85 SYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGlkyegsiyynqegtSWYEGDWVYNIKKGWGIRCYK 164
Cdd:PLN03185   79 TYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANG--------------NVYLGDMKGGKMSGKGTLTWV 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1907161034 165 SGNIYEGQWENNMRHGEGRMRWlTTNEEYTGHWEKGIQNGFGT 207
Cdd:PLN03185  145 SGDSYEGQWLDGMMHGFGVYTW-SDGGCYVGTWTRGLKDGKGV 186
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 213-281 3.14e-08

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 57.54  E-value: 3.14e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907161034 213 KRIPNSQYplrneYIGEFVNGFRHGQGKFYYASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSNDHI 281
Cdd:PLN03185    3 LVLSNGDF-----YSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYM 66
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
121-279 3.83e-06

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 47.76  E-value: 3.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 121 QGTYIWADGLKYEGSIYYNQEGTSWYEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWLTTNEEYTGHWEKG 200
Cdd:COG2849     9 ISKYLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGQLKSEGTYKNG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907161034 201 IQNGFGThTWFlkriPNSQYplrnEYIGEFVNGFRHGQGKFYYASGA-MYEGEWASNKKQGRGRMTFKNGH-VYEGLFSN 278
Cdd:COG2849    89 KLEGEWK-EYY----ENGKL----KSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKDGVWKYYDENGKlVKEEEYKN 159


                  .
gi 1907161034 279 D 279
Cdd:COG2849   160 G 160
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
167-186 2.96e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 41.17  E-value: 2.96e-05
                           10        20
                   ....*....|....*....|
gi 1907161034  167 NIYEGQWENNMRHGEGRMRW 186
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 226-248 3.30e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 41.24  E-value: 3.30e-05
                          10        20
                  ....*....|....*....|...
gi 1907161034 226 YIGEFVNGFRHGQGKFYYASGAM 248
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 109-129 5.03e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 40.85  E-value: 5.03e-05
                          10        20
                  ....*....|....*....|.
gi 1907161034 109 YHGMFSEGLMHGQGTYIWADG 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
107-128 8.37e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 40.02  E-value: 8.37e-05
                           10        20
                   ....*....|....*....|..
gi 1907161034  107 NTYHGMFSEGLMHGQGTYIWAD 128
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
224-244 3.14e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.48  E-value: 3.14e-04
                           10        20
                   ....*....|....*....|.
gi 1907161034  224 NEYIGEFVNGFRHGQGKFYYA 244
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYA 21
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 169-186 1.02e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 1.02e-03
                          10
                  ....*....|....*...
gi 1907161034 169 YEGQWENNMRHGEGRMRW 186
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTW 18
vATP-synt_E pfam01991
ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as ...
 724-771 1.20e-03

ATP synthase (E/31 kDa) subunit; This family includes the vacuolar ATP synthase E subunit, as well as the archaebacterial ATP synthase E subunit.


Pssm-ID: 396537 [Multi-domain]  Cd Length: 199  Bit Score: 40.83  E-value: 1.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907161034 724 AYKREEMLKEKVKENQLQEAELAQQRQIENEELEARLNIL--REE-------EARKQ 771
Cdd:pfam01991  28 LVQEAEEKIDEIYEKKEKQAEMQKKIIISNAKNEARLKVLeaREEildevfnEAEKK 84
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
247-268 2.88e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.78  E-value: 2.88e-03
                           10        20
                   ....*....|....*....|..
gi 1907161034  247 AMYEGEWASNKKQGRGRMTFKN 268
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 249-271 4.71e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.08  E-value: 4.71e-03
                          10        20
                  ....*....|....*....|...
gi 1907161034 249 YEGEWASNKKQGRGRMTFKNGHV 271
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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