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Conserved domains on  [gi|1907132816|ref|XP_036017577|]
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tetratricopeptide repeat protein 9C isoform X1 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1008599)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpI super family cl34822
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
6-155 7.76e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG4785:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 7.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   6 QEAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQenilhtiqTHCYNNLAACLLQM 85
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQAL----------------------ELDPDL--------AEAYNNRGLAYLLL 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  86 EpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSEL 155
Cdd:COG4785   121 G--DYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKL 188
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
6-155 7.76e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 7.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   6 QEAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQenilhtiqTHCYNNLAACLLQM 85
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQAL----------------------ELDPDL--------AEAYNNRGLAYLLL 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  86 EpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSEL 155
Cdd:COG4785   121 G--DYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKL 188
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 82-152 2.76e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 2.76e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907132816  82 LLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQ 152
Cdd:TIGR02917 269 LVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQ 339
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 89-152 3.13e-07

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.78  E-value: 3.13e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPkDANVRRYLQLTQ 152
Cdd:cd24142    15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP-DGGYEKYLYLGQ 77
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 89-150 6.02e-05

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 41.60  E-value: 6.02e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQL 150
Cdd:NF040959   86 QYDRAIKVLEKVLSLAPDHVKAAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRLGL 147
TPR_19 pfam14559
Tetratricopeptide repeat;
89-146 2.69e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 34.87  E-value: 2.69e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRR 146
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
6-155 7.76e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 7.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   6 QEAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQenilhtiqTHCYNNLAACLLQM 85
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQAL----------------------ELDPDL--------AEAYNNRGLAYLLL 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  86 EpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSEL 155
Cdd:COG4785   121 G--DYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKL 188
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 82-152 2.76e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 2.76e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907132816  82 LLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQ 152
Cdd:TIGR02917 269 LVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQ 339
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 89-152 3.13e-07

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.78  E-value: 3.13e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPkDANVRRYLQLTQ 152
Cdd:cd24142    15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP-DGGYEKYLYLGQ 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1-145 4.54e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 4.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   1 MEKRLQE----AQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQENIlhtiqthcYN 76
Cdd:COG4235     6 LRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKAL----------------------RLDPDNADA--------LL 55

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907132816  77 NLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVR 145
Cdd:COG4235    56 DLAEALLAAG--DTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
74-158 1.06e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.23  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  74 CYNNLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQS 153
Cdd:COG0457    10 AYNNLGLAYRRLG--RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87


                  ....*
gi 1907132816 154 ELSSY 158
Cdd:COG0457    88 ALGRY 92
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-158 1.45e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   6 QEAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQENIlhtiqthcYNNLAACLLQM 85
Cdd:COG0457    40 DDAEALYNLGLAYLRLGRYEEALADYEQAL----------------------ELDPDDAEA--------LNNLGLALQAL 89

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907132816  86 EpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSELSSY 158
Cdd:COG0457    90 G--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
7-148 2.32e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 2.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   7 EAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQENIlhtiqthcYNNLAACLLQME 86
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKAL----------------------ELDPDDAEA--------LYNLGLAYLRLG 56

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907132816  87 pvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG0457    57 --RYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 2-127 3.61e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.05  E-value: 3.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   2 EKRLQEAQVYKEEGNQRYREGKYRDAVSRYHRALLqlrgldpslpsplsslGPQGPALtpeqenilhtiqthcYNNLAAC 81
Cdd:TIGR00990 121 EERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIE----------------CKPDPVY---------------YSNRAAC 169

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907132816  82 LLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRA 127
Cdd:TIGR00990 170 HNALG--DWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADA 213
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 75-148 4.16e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 4.16e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907132816  75 YNNLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG4235    20 WLLLGRAYLRLG--RYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL 91
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 89-150 6.02e-05

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 41.60  E-value: 6.02e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQL 150
Cdd:NF040959   86 QYDRAIKVLEKVLSLAPDHVKAAYRKGVALLKIKDYEKAVEDLEEALEEKPDNFNLNYRLGL 147
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 89-148 1.19e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 1.19e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG2956    57 EYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLL 116
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 89-148 3.65e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 3.65e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG4783    19 DYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL 78
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 75-148 1.55e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.79  E-value: 1.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907132816  75 YNNLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG2956   113 LRLLAEIYEQEG--DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLL 184
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 66-148 2.08e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 37.58  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  66 ILHTIQTHCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPkDANVR 145
Cdd:COG3071   216 LREALKRQWDPRLVRLYGRLQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRP-SAEAY 294


                  ...
gi 1907132816 146 RYL 148
Cdd:COG3071   295 AEL 297
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 71-165 2.21e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.40  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  71 QTHCYNNLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQL 150
Cdd:COG2956   143 NAHAYCELAELYLEQG--DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                          90
                  ....*....|....*
gi 1907132816 151 TQSELSSYHRKEKQL 165
Cdd:COG2956   221 LYEKLGDPEEALELL 235
TPR_19 pfam14559
Tetratricopeptide repeat;
89-146 2.69e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 34.87  E-value: 2.69e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRR 146
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 89-165 2.80e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.48  E-value: 2.80e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907132816  89 NYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQL 165
Cdd:COG5010    69 DFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAAL 145
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 98-148 3.17e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.14  E-value: 3.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1907132816  98 QKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG4235     7 RQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 89-148 5.33e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 34.97  E-value: 5.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907132816  89 NYERVREYSQKVLERQPDN---AKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYL 148
Cdd:COG1729     8 DYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDAL 70
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 89-146 5.89e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 34.97  E-value: 5.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907132816  89 NYERVREYSQKVLERQPDNAK---ALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRR 146
Cdd:COG1729    45 DYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKE 105
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
75-167 6.10e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 36.14  E-value: 6.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  75 YNNLAACLLQMEpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSE 154
Cdd:COG0457   113 LYNLGLALLELG--RYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALAL 190

                          90
                  ....*....|...
gi 1907132816 155 LSSYHRKEKQLYL 167
Cdd:COG0457   191 AAAEVLLALLLAL 203
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 6-165 7.90e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 34.78  E-value: 7.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816   6 QEAQVYKEEGNQRYREGKYRDAVSRYHRALlqlrgldpslpsplsslgpqgpALTPEQENIlhtiqthcYNNLAACLLQM 85
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKAL----------------------ELDPDNPEA--------FALLGEILLQL 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907132816  86 EpvNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQL 165
Cdd:COG4783    52 G--DLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAAL 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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