|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
201-411 |
7.22e-99 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 305.65 E-value: 7.22e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 201 FWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRL 280
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 281 DetpdgrKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRII 360
Cdd:cd07993 81 G------KDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1907131791 361 EGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLE 411
Cdd:cd07993 155 EEELYAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
129-656 |
9.57e-82 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 276.80 E-value: 9.57e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 129 VTENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHk 208
Cdd:COG2937 122 LIERLLRSPAVRKAIEEEAKSKG---------ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD- 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 209 gQLEMVKAATETNlPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLdetpdgRK 288
Cdd:COG2937 192 -NLERLRELAKGH-EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGINLNFWPLGPILRRGGAFFIRRSF------KG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 289 DILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGH-YNGE 367
Cdd:COG2937 264 NKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGsYAKE 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 368 QLGKPKKNESLWSVARGvIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDEHQ-D 446
Cdd:COG2937 344 LRGGEKKKESLGGLLRA-LRKLRRRFGRVYVNFGEPISLSEYL-------------------------------DQHVpD 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 447 LSSNESRNPAdeaFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGI---HLSTLVEDFFVMKEEVLARDFDL 523
Cdd:COG2937 392 WRESEDLRPE---WLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALteaELLAQLDLYLDLLRNVPYSLSVT 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 524 GFSGNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACsiyAVLNKRCsggsa 603
Cdd:COG2937 469 LPELTPEELLEHLLSL--GLIEVEKDGLGDVISIDDEQAV----LLTYYRNNILHLFALPALIAS---ALLANRR----- 534
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1907131791 604 gglgnlISQEQLVRKAASLCYLLSNEGTISLPcQTFYQVCHETVGKFIQYGIL 656
Cdd:COG2937 535 ------ISRAELLELVRLLYPLLKAELFLRWD-AEFEEVLDEELDELVRQGLL 580
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
71-629 |
3.77e-49 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 186.59 E-value: 3.77e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 71 TPQSWERFFNPSI----------PSLGLRNVIYINETHTRhrgwLARRLSYIL---FVQERDVHKG--------MFatsv 129
Cdd:PRK04974 150 VPGRLRKLFAILWlgrdtfvrfsPPVSLRYMADEHGTDKR----IARKLARVArvhFRRQRLAAIGpdlphrqaLF---- 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 130 tENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHkg 209
Cdd:PRK04974 222 -NKLLASPAIKKAIEDEAKSKK---------ISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVH-- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 210 QLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRrldeTPDGRKd 289
Cdd:PRK04974 290 NAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRR----SFKGNK- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 290 iLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDT-LSSNTIPdILVIPVGISYDRIIEGH-YNGE 367
Cdd:PRK04974 365 -LYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLLQPKTGMLAMTLQAmLRGSRRP-ITLVPVYIGYEHVMEVGtYAKE 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 368 QLGKPKKNESLWSVARgVIRMLRkNYGYVRVDFAQPFSLKEYLEGQsqkpvsAPLSLEQ-ALLPAILPSRPNDVADehqd 446
Cdd:PRK04974 443 LRGAPKEKESLFQVLR-GIRKLR-NFGQGYVNFGEPIPLNDYLNQH------VPEWRESiDPIEEQRPAWLTPAVN---- 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 447 lssnesrnpadeafrrRLIANLAEHIlftaSKSCAIMSTHIVACLLLyRHRQgihlstlvedfFVMKEEVLARDFDLGFS 526
Cdd:PRK04974 511 ----------------NLANQVMVRI----NNAAAANPVNLCALALL-ASRQ-----------RALDREQLIEQLDLYLQ 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 527 ---------------GNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 591
Cdd:PRK04974 559 llrnvpyssdttvpeGSGEELIDHALSL--NKFEVEKDTLGDIISLDREQAV----LMTYYRNNILHLFVLPSLIASIVT 632
|
570 580 590
....*....|....*....|....*....|....*...
gi 1907131791 592 AvlNKRcsggsagglgnlISQEQLVRKAASLCYLLSNE 629
Cdd:PRK04974 633 H--NRR------------ISRDELLRIVNALYPFLKAE 656
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
80-587 |
3.17e-47 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 182.38 E-value: 3.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 80 NPSIPSLGLRNVIYINETHTRHRGWLArrlsyilfvqerDVHKGMFATSVTeNVLSSSRVQEAIAEVAAElnpDGSAQQQ 159
Cdd:PTZ00374 508 TPLLTRKYFDDVVWTQRVGLTANGWRF------------AATPGLTPESLT-SILAQPSIQRLMTALAKK---EGASEKD 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 160 skaiqkVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATET-NLPLLFLPVHRSHIDYLL 238
Cdd:PTZ00374 572 ------VEARAKAILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAMpRVAVVLLPLHRSYIDFII 645
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 239 LTFILFCHNIKAPYIASGNN-LNIPVFSTLIHKLGGFFIRRRLdetpdgRKDILYRALLHGHVVELLRQQQFLEIFLEGT 317
Cdd:PTZ00374 646 MTYLLAVMGLPLPHVCAGDDfLRMGPIATLMRGSGAFFMRRSF------RDDPLYAALFKEYVRHLVLRRRPLEFFIEGT 719
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 318 RSRSGKTSCARAGLLSVVVDTL--SSNTIPDILVIPVGISYDRIIEGH-YNGEQLGKPKKNESLWSVARGViRMLRKNYG 394
Cdd:PTZ00374 720 RSRTGKTMAPKLGLLKFICDTFyeGQQELDDVLIIPVSLSYDELLETTlYAKEQLGVSKPKENPGNLLRAR-SLLKRRHG 798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 395 YVRVDFAQPFSLKEYLEGQSQKPvsaplsleqallpaiLPSRPND--VADEHQDLSSNESRNPADEAFRRRLIANLAEHI 472
Cdd:PTZ00374 799 KIHVHIGEPVSLRSFKDHPLQCP---------------LPFEPKGeaTTSVCKTLDTTPSIARKSSITPPRVLTNIAWHL 863
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 473 LFTASKSCAIMSTHIVA-----------CLLLYRHRQGIhlsTLVEDFFVMKEEVLARDfdlGFSGNSEDVVMHAIQLLG 541
Cdd:PTZ00374 864 THKLQRNTIITPTALVAavleclgptagAMPLAEVQQGM---TWLRTNIRRRGAALSDD---CANLNPETMVRKALTHLQ 937
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1907131791 542 NCVTIthTSRKDEFFITPSTTVpSVFELNFYSNGVLHVFIMEAIIA 587
Cdd:PTZ00374 938 EFVEI--TDEMSEVIYVRQDVV-TRLGVNICSNQLIHVFMDEAVVA 980
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
220-355 |
2.90e-25 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 101.59 E-value: 2.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 220 TNLPLLFLPVHRSHIDYLLLTFILFCHNiKAPYIASGNNL-NIPVFSTLIHKLGGFFIRrrldetpdgRKDILYRALLHG 298
Cdd:pfam01553 12 RGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFID---------RKNRKDAAGTLE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907131791 299 HVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 355
Cdd:pfam01553 82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
224-357 |
3.02e-23 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 95.50 E-value: 3.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 224 LLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDEtpdgrkdiLYRALLHgHVVEL 303
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGR--------KARAALR-EAVEL 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1907131791 304 LRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGISYD 357
Cdd:smart00563 72 LKEGEWLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
185-360 |
7.71e-12 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 65.42 E-value: 7.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 185 MIRLTGWVLLKLFNsffWNIQIHkgQLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 264
Cdd:COG0204 15 LVRLWARLLLRLLG---VRVRVE--GLENLPADG----PVLIVANHQSWLDILLLLAAL---PRPVRFVAKKELFKIPLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 265 STLIHKLGGFFIRRRldetpDGRKDIlyRALLHghVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssnti 344
Cdd:COG0204 83 GWLLRALGAIPVDRS-----KRRAAL--RALRQ--AVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEA------ 147
|
170
....*....|....*.
gi 1907131791 345 pDILVIPVGISYDRII 360
Cdd:COG0204 148 -GVPIVPVAIDGTERA 162
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
364-593 |
1.72e-11 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 66.77 E-value: 1.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 364 YNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDE 443
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQLSLKLGRVYVRFGEPWSLREFL-------------------------------DE 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 444 HQDlssnesRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIV-ACLLLYRHRqGIHLSTLVEDFFVMKEEVLARDFD 522
Cdd:pfam19277 50 QGD------RPATDAARRRLALQKLAFEVLSRINRVTPVMPTALVgTVLLTLRGR-ALTLSELIRRVEWLLDYIRARGGP 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907131791 523 LGFSGN--SEDVVMHAIQLLGNCVTITHTSRKDE--FFITPSttvpSVFELNFYSNGVLHVFIMEAIIACSIYAV 593
Cdd:pfam19277 123 VAHFGDlrTEEVVDRALDVLGNAGLVTRVDGGPEpvYYIAPE----DHFQASFYRNMTIHLFVERAIVELALLTK 193
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
201-411 |
7.22e-99 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 305.65 E-value: 7.22e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 201 FWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRL 280
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 281 DetpdgrKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRII 360
Cdd:cd07993 81 G------KDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1907131791 361 EGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLE 411
Cdd:cd07993 155 EEELYAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
129-656 |
9.57e-82 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 276.80 E-value: 9.57e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 129 VTENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHk 208
Cdd:COG2937 122 LIERLLRSPAVRKAIEEEAKSKG---------ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD- 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 209 gQLEMVKAATETNlPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLdetpdgRK 288
Cdd:COG2937 192 -NLERLRELAKGH-EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGINLNFWPLGPILRRGGAFFIRRSF------KG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 289 DILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGH-YNGE 367
Cdd:COG2937 264 NKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGsYAKE 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 368 QLGKPKKNESLWSVARGvIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDEHQ-D 446
Cdd:COG2937 344 LRGGEKKKESLGGLLRA-LRKLRRRFGRVYVNFGEPISLSEYL-------------------------------DQHVpD 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 447 LSSNESRNPAdeaFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGI---HLSTLVEDFFVMKEEVLARDFDL 523
Cdd:COG2937 392 WRESEDLRPE---WLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALteaELLAQLDLYLDLLRNVPYSLSVT 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 524 GFSGNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACsiyAVLNKRCsggsa 603
Cdd:COG2937 469 LPELTPEELLEHLLSL--GLIEVEKDGLGDVISIDDEQAV----LLTYYRNNILHLFALPALIAS---ALLANRR----- 534
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1907131791 604 gglgnlISQEQLVRKAASLCYLLSNEGTISLPcQTFYQVCHETVGKFIQYGIL 656
Cdd:COG2937 535 ------ISRAELLELVRLLYPLLKAELFLRWD-AEFEEVLDEELDELVRQGLL 580
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
71-629 |
3.77e-49 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 186.59 E-value: 3.77e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 71 TPQSWERFFNPSI----------PSLGLRNVIYINETHTRhrgwLARRLSYIL---FVQERDVHKG--------MFatsv 129
Cdd:PRK04974 150 VPGRLRKLFAILWlgrdtfvrfsPPVSLRYMADEHGTDKR----IARKLARVArvhFRRQRLAAIGpdlphrqaLF---- 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 130 tENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHkg 209
Cdd:PRK04974 222 -NKLLASPAIKKAIEDEAKSKK---------ISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVH-- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 210 QLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRrldeTPDGRKd 289
Cdd:PRK04974 290 NAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRR----SFKGNK- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 290 iLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDT-LSSNTIPdILVIPVGISYDRIIEGH-YNGE 367
Cdd:PRK04974 365 -LYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLLQPKTGMLAMTLQAmLRGSRRP-ITLVPVYIGYEHVMEVGtYAKE 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 368 QLGKPKKNESLWSVARgVIRMLRkNYGYVRVDFAQPFSLKEYLEGQsqkpvsAPLSLEQ-ALLPAILPSRPNDVADehqd 446
Cdd:PRK04974 443 LRGAPKEKESLFQVLR-GIRKLR-NFGQGYVNFGEPIPLNDYLNQH------VPEWRESiDPIEEQRPAWLTPAVN---- 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 447 lssnesrnpadeafrrRLIANLAEHIlftaSKSCAIMSTHIVACLLLyRHRQgihlstlvedfFVMKEEVLARDFDLGFS 526
Cdd:PRK04974 511 ----------------NLANQVMVRI----NNAAAANPVNLCALALL-ASRQ-----------RALDREQLIEQLDLYLQ 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 527 ---------------GNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 591
Cdd:PRK04974 559 llrnvpyssdttvpeGSGEELIDHALSL--NKFEVEKDTLGDIISLDREQAV----LMTYYRNNILHLFVLPSLIASIVT 632
|
570 580 590
....*....|....*....|....*....|....*...
gi 1907131791 592 AvlNKRcsggsagglgnlISQEQLVRKAASLCYLLSNE 629
Cdd:PRK04974 633 H--NRR------------ISRDELLRIVNALYPFLKAE 656
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
80-587 |
3.17e-47 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 182.38 E-value: 3.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 80 NPSIPSLGLRNVIYINETHTRHRGWLArrlsyilfvqerDVHKGMFATSVTeNVLSSSRVQEAIAEVAAElnpDGSAQQQ 159
Cdd:PTZ00374 508 TPLLTRKYFDDVVWTQRVGLTANGWRF------------AATPGLTPESLT-SILAQPSIQRLMTALAKK---EGASEKD 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 160 skaiqkVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATET-NLPLLFLPVHRSHIDYLL 238
Cdd:PTZ00374 572 ------VEARAKAILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAMpRVAVVLLPLHRSYIDFII 645
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 239 LTFILFCHNIKAPYIASGNN-LNIPVFSTLIHKLGGFFIRRRLdetpdgRKDILYRALLHGHVVELLRQQQFLEIFLEGT 317
Cdd:PTZ00374 646 MTYLLAVMGLPLPHVCAGDDfLRMGPIATLMRGSGAFFMRRSF------RDDPLYAALFKEYVRHLVLRRRPLEFFIEGT 719
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 318 RSRSGKTSCARAGLLSVVVDTL--SSNTIPDILVIPVGISYDRIIEGH-YNGEQLGKPKKNESLWSVARGViRMLRKNYG 394
Cdd:PTZ00374 720 RSRTGKTMAPKLGLLKFICDTFyeGQQELDDVLIIPVSLSYDELLETTlYAKEQLGVSKPKENPGNLLRAR-SLLKRRHG 798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 395 YVRVDFAQPFSLKEYLEGQSQKPvsaplsleqallpaiLPSRPND--VADEHQDLSSNESRNPADEAFRRRLIANLAEHI 472
Cdd:PTZ00374 799 KIHVHIGEPVSLRSFKDHPLQCP---------------LPFEPKGeaTTSVCKTLDTTPSIARKSSITPPRVLTNIAWHL 863
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 473 LFTASKSCAIMSTHIVA-----------CLLLYRHRQGIhlsTLVEDFFVMKEEVLARDfdlGFSGNSEDVVMHAIQLLG 541
Cdd:PTZ00374 864 THKLQRNTIITPTALVAavleclgptagAMPLAEVQQGM---TWLRTNIRRRGAALSDD---CANLNPETMVRKALTHLQ 937
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1907131791 542 NCVTIthTSRKDEFFITPSTTVpSVFELNFYSNGVLHVFIMEAIIA 587
Cdd:PTZ00374 938 EFVEI--TDEMSEVIYVRQDVV-TRLGVNICSNQLIHVFMDEAVVA 980
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
129-593 |
7.34e-40 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 158.34 E-value: 7.34e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 129 VTENVLSSSRVQEAIAEVAAELNPDGSAqqqskaiqkVKRKARKILQEMVATVSPGMIRLTGwVLLKLFNS-FFWNIQIH 207
Cdd:PRK03355 184 VKPEILASARFRAGLAKIAAKLGRPPGA---------TVREAGKMLDELVAGWSRVSVDLVS-VLGRLFSRgFDPEIDYD 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 208 KGQLEMVKAATEtNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPdgr 287
Cdd:PRK03355 254 EYELAALRALLE-EHPAVLLFSHRSYIDGLVVPVAMQENRLPPVHVFGGINLSFGPMGPIMRRSGMIFIRRNIGDDP--- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 288 kdiLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIE-GHYNG 366
Cdd:PRK03355 330 ---LYKYVLREYVGYLVEKRFNLSWYIEGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEiGEYAA 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 367 EQLGKPKKNESL-WSVarGVIRML-RKNYGYVRVDFAQPFSLKEYLeGQSQKPVSAPLSLEQALLPAIlpsrpndvadeh 444
Cdd:PRK03355 407 EARGGEKTPEGLrWLY--NYIKAQgERNYGKIYVRFGEPVSMRQYL-GAPHGPLTQDPDAKRLALQKM------------ 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 445 qdlssnesrnpadeAFRRRLIANLAEHILFTASKSCAIMST-----------HIVACLLLYRHRQGIHLSTlvedffvmk 513
Cdd:PRK03355 472 --------------AFEVAWRINQVTPVTATSLVSLLLLGTrgraltldelhHTLQDSLDYLERRQLPVST--------- 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 514 eevlaRDFDLGfsgnSEDVVMHAIQLL--GNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 591
Cdd:PRK03355 529 -----SALRLR----DPEGVRAALDALsnGGPVTRVDSGREPVWYIAPDDHL----VAAFYRNSVIHAFLERAIVELALA 595
|
..
gi 1907131791 592 AV 593
Cdd:PRK03355 596 AA 597
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
220-355 |
2.90e-25 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 101.59 E-value: 2.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 220 TNLPLLFLPVHRSHIDYLLLTFILFCHNiKAPYIASGNNL-NIPVFSTLIHKLGGFFIRrrldetpdgRKDILYRALLHG 298
Cdd:pfam01553 12 RGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFID---------RKNRKDAAGTLE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907131791 299 HVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 355
Cdd:pfam01553 82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
224-357 |
3.02e-23 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 95.50 E-value: 3.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 224 LLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDEtpdgrkdiLYRALLHgHVVEL 303
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGR--------KARAALR-EAVEL 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1907131791 304 LRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGISYD 357
Cdd:smart00563 72 LKEGEWLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
133-429 |
1.64e-19 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 93.47 E-value: 1.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 133 VLSSSRVQEAIAEVAAEL--NPDGsaqqqskaiqkVKRKARKILQEMVATVSPGMIRltGWvllKLFNSFF---WNIQIH 207
Cdd:PRK11915 38 LLDARWYDERLRALADELgrDPDS-----------VRAEAAGYLREMAASLDERAVQ--AW---RGFSRWLmraYDVLVD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 208 KGQLEMVKAaTETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPdgr 287
Cdd:PRK11915 102 EDQITQLRK-LDRKATLAFAFSHRSYLDGMLLPEVILANRLSPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIP--- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 288 kdiLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIE-GHYNG 366
Cdd:PRK11915 178 ---VYRFVLRAYAAQLVQNHVNLTWSIEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEvEAMTT 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907131791 367 EQLGKPKKNESLwsvaRGVIRMLRKN---YGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALL 429
Cdd:PRK11915 255 EAYGAVKRPEDL----RFLVRLARQQgerLGRAYLDFGEPLPLRKRLQELRADKSGTGSEIERIAL 316
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
185-360 |
7.71e-12 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 65.42 E-value: 7.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 185 MIRLTGWVLLKLFNsffWNIQIHkgQLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 264
Cdd:COG0204 15 LVRLWARLLLRLLG---VRVRVE--GLENLPADG----PVLIVANHQSWLDILLLLAAL---PRPVRFVAKKELFKIPLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 265 STLIHKLGGFFIRRRldetpDGRKDIlyRALLHghVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssnti 344
Cdd:COG0204 83 GWLLRALGAIPVDRS-----KRRAAL--RALRQ--AVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEA------ 147
|
170
....*....|....*.
gi 1907131791 345 pDILVIPVGISYDRII 360
Cdd:COG0204 148 -GVPIVPVAIDGTERA 162
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
364-593 |
1.72e-11 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 66.77 E-value: 1.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 364 YNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDE 443
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQLSLKLGRVYVRFGEPWSLREFL-------------------------------DE 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 444 HQDlssnesRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIV-ACLLLYRHRqGIHLSTLVEDFFVMKEEVLARDFD 522
Cdd:pfam19277 50 QGD------RPATDAARRRLALQKLAFEVLSRINRVTPVMPTALVgTVLLTLRGR-ALTLSELIRRVEWLLDYIRARGGP 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907131791 523 LGFSGN--SEDVVMHAIQLLGNCVTITHTSRKDE--FFITPSttvpSVFELNFYSNGVLHVFIMEAIIACSIYAV 593
Cdd:pfam19277 123 VAHFGDlrTEEVVDRALDVLGNAGLVTRVDGGPEpvYYIAPE----DHFQASFYRNMTIHLFVERAIVELALLTK 193
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
196-356 |
6.18e-10 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 59.21 E-value: 6.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 196 LFNSFFWNIQIHKgqLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILFcHNIKapYIASGNNLNIPVFSTLIHKLGGFF 275
Cdd:cd07989 4 LLRLLGVRVRVEG--LENLPPKG----PVIIVANHQSYLDPLVLGAALP-RPIR--FVAKKELFKIPFLGWLLRLLGAIP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 276 IRRRldetpDGRKDIlyRALLhgHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 355
Cdd:cd07989 75 IDRG-----NGRSAR--EALR--EAIEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEA-------GVPIVPVAIS 138
|
.
gi 1907131791 356 Y 356
Cdd:cd07989 139 G 139
|
|
| LPLAT_AAK14816-like |
cd07992 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
186-358 |
4.24e-06 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Pssm-ID: 153254 [Multi-domain] Cd Length: 203 Bit Score: 48.41 E-value: 4.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 186 IRLTGWVLLKLFnsfFWNIQIHKGQLEmvkaatETNLPLLFLPVHR-SHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 264
Cdd:cd07992 1 VRLLSRVILRIY---FRRITVVGRENV------PKDGPVIFLGNHPnALIDPLLLAATL---RRPVRFLAKADLFKNPLI 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 265 STLIHKLGGFFIRRRLDETPDGRKDILYRALLHGhVVELLRQQQFLEIFLEGTrSRSG------KTSCARAGLlsvvvdT 338
Cdd:cd07992 69 GWLLESFGAIPVYRPKDLARGGIGKISNAAVFDA-VGEALKAGGAIGIFPEGG-SHDRprllplKAGAARMAL------E 140
|
170 180
....*....|....*....|
gi 1907131791 339 LSSNTIPDILVIPVGISYDR 358
Cdd:cd07992 141 ALEAGQKDVKIVPVGLNYED 160
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
223-359 |
1.65e-05 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 46.25 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131791 223 PLLFLPVHRSHIDYLLLTFILFC---HNIKAPYIASGnNLNIPVFStlihKLGGFFIRRRLDEtpDGRKDILYrallhgh 299
Cdd:cd06551 27 PVLFVSNHSSWWDGLILFLLLERglrRDVYGLMDEEL-LERYPFFT----RLGAFSVDRDSPR--SAAKSLKY------- 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907131791 300 VVELLRQ-QQFLEIFLEGTRSRSGKtscaRAGLLSVVVDTLSsnTIPDILVIPVGISYDRI 359
Cdd:cd06551 93 VARLLSKpGSVVWIFPEGTRTRRDK----RPLQFKPGVAHLA--EKAGVPIVPVALRYTFE 147
|
|
| |
