|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
218-428 |
7.48e-99 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 306.04 E-value: 7.48e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 218 FWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRL 297
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 298 DetpdgrKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRII 377
Cdd:cd07993 81 G------KDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1907131786 378 EGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLE 428
Cdd:cd07993 155 EEELYAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
146-673 |
1.40e-81 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 276.80 E-value: 1.40e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 146 VTENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHk 225
Cdd:COG2937 122 LIERLLRSPAVRKAIEEEAKSKG---------ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD- 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 226 gQLEMVKAATETNlPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLdetpdgRK 305
Cdd:COG2937 192 -NLERLRELAKGH-EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGINLNFWPLGPILRRGGAFFIRRSF------KG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 306 DILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGH-YNGE 384
Cdd:COG2937 264 NKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGsYAKE 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 385 QLGKPKKNESLWSVARGvIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDEHQ-D 463
Cdd:COG2937 344 LRGGEKKKESLGGLLRA-LRKLRRRFGRVYVNFGEPISLSEYL-------------------------------DQHVpD 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 464 LSSNESRNPAdeaFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGI---HLSTLVEDFFVMKEEVLARDFDL 540
Cdd:COG2937 392 WRESEDLRPE---WLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALteaELLAQLDLYLDLLRNVPYSLSVT 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 541 GFSGNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACsiyAVLNKRCsggsa 620
Cdd:COG2937 469 LPELTPEELLEHLLSL--GLIEVEKDGLGDVISIDDEQAV----LLTYYRNNILHLFALPALIAS---ALLANRR----- 534
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1907131786 621 gglgnlISQEQLVRKAASLCYLLSNEGTISLPcQTFYQVCHETVGKFIQYGIL 673
Cdd:COG2937 535 ------ISRAELLELVRLLYPLLKAELFLRWD-AEFEEVLDEELDELVRQGLL 580
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
88-646 |
4.32e-49 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 186.59 E-value: 4.32e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 88 TPQSWERFFNPSI----------PSLGLRNVIYINETHTRhrgwLARRLSYIL---FVQERDVHKG--------MFatsv 146
Cdd:PRK04974 150 VPGRLRKLFAILWlgrdtfvrfsPPVSLRYMADEHGTDKR----IARKLARVArvhFRRQRLAAIGpdlphrqaLF---- 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 147 tENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHkg 226
Cdd:PRK04974 222 -NKLLASPAIKKAIEDEAKSKK---------ISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVH-- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 227 QLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRrldeTPDGRKd 306
Cdd:PRK04974 290 NAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRR----SFKGNK- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 307 iLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDT-LSSNTIPdILVIPVGISYDRIIEGH-YNGE 384
Cdd:PRK04974 365 -LYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLLQPKTGMLAMTLQAmLRGSRRP-ITLVPVYIGYEHVMEVGtYAKE 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 385 QLGKPKKNESLWSVARgVIRMLRkNYGYVRVDFAQPFSLKEYLEGQsqkpvsAPLSLEQ-ALLPAILPSRPNDVADehqd 463
Cdd:PRK04974 443 LRGAPKEKESLFQVLR-GIRKLR-NFGQGYVNFGEPIPLNDYLNQH------VPEWRESiDPIEEQRPAWLTPAVN---- 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 464 lssnesrnpadeafrrRLIANLAEHIlftaSKSCAIMSTHIVACLLLyRHRQgihlstlvedfFVMKEEVLARDFDLGFS 543
Cdd:PRK04974 511 ----------------NLANQVMVRI----NNAAAANPVNLCALALL-ASRQ-----------RALDREQLIEQLDLYLQ 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 544 ---------------GNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 608
Cdd:PRK04974 559 llrnvpyssdttvpeGSGEELIDHALSL--NKFEVEKDTLGDIISLDREQAV----LMTYYRNNILHLFVLPSLIASIVT 632
|
570 580 590
....*....|....*....|....*....|....*...
gi 1907131786 609 AvlNKRcsggsagglgnlISQEQLVRKAASLCYLLSNE 646
Cdd:PRK04974 633 H--NRR------------ISRDELLRIVNALYPFLKAE 656
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
97-604 |
4.29e-47 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 182.00 E-value: 4.29e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 97 NPSIPSLGLRNVIYINETHTRHRGWLArrlsyilfvqerDVHKGMFATSVTeNVLSSSRVQEAIAEVAAElnpDGSAQQQ 176
Cdd:PTZ00374 508 TPLLTRKYFDDVVWTQRVGLTANGWRF------------AATPGLTPESLT-SILAQPSIQRLMTALAKK---EGASEKD 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 177 skaiqkVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATET-NLPLLFLPVHRSHIDYLL 255
Cdd:PTZ00374 572 ------VEARAKAILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAMpRVAVVLLPLHRSYIDFII 645
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 256 LTFILFCHNIKAPYIASGNN-LNIPVFSTLIHKLGGFFIRRRLdetpdgRKDILYRALLHGHVVELLRQQQFLEIFLEGT 334
Cdd:PTZ00374 646 MTYLLAVMGLPLPHVCAGDDfLRMGPIATLMRGSGAFFMRRSF------RDDPLYAALFKEYVRHLVLRRRPLEFFIEGT 719
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 335 RSRSGKTSCARAGLLSVVVDTL--SSNTIPDILVIPVGISYDRIIEGH-YNGEQLGKPKKNESLWSVARGViRMLRKNYG 411
Cdd:PTZ00374 720 RSRTGKTMAPKLGLLKFICDTFyeGQQELDDVLIIPVSLSYDELLETTlYAKEQLGVSKPKENPGNLLRAR-SLLKRRHG 798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 412 YVRVDFAQPFSLKEYLEGQSQKPvsaplsleqallpaiLPSRPND--VADEHQDLSSNESRNPADEAFRRRLIANLAEHI 489
Cdd:PTZ00374 799 KIHVHIGEPVSLRSFKDHPLQCP---------------LPFEPKGeaTTSVCKTLDTTPSIARKSSITPPRVLTNIAWHL 863
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 490 LFTASKSCAIMSTHIVA-----------CLLLYRHRQGIhlsTLVEDFFVMKEEVLARDfdlGFSGNSEDVVMHAIQLLG 558
Cdd:PTZ00374 864 THKLQRNTIITPTALVAavleclgptagAMPLAEVQQGM---TWLRTNIRRRGAALSDD---CANLNPETMVRKALTHLQ 937
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1907131786 559 NCVTIthTSRKDEFFITPSTTVpSVFELNFYSNGVLHVFIMEAIIA 604
Cdd:PTZ00374 938 EFVEI--TDEMSEVIYVRQDVV-TRLGVNICSNQLIHVFMDEAVVA 980
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
237-372 |
2.62e-25 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 101.97 E-value: 2.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 237 TNLPLLFLPVHRSHIDYLLLTFILFCHNiKAPYIASGNNL-NIPVFSTLIHKLGGFFIRrrldetpdgRKDILYRALLHG 315
Cdd:pfam01553 12 RGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFID---------RKNRKDAAGTLE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907131786 316 HVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 372
Cdd:pfam01553 82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
241-374 |
3.06e-23 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 95.50 E-value: 3.06e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 241 LLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDEtpdgrkdiLYRALLHgHVVEL 320
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGR--------KARAALR-EAVEL 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1907131786 321 LRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGISYD 374
Cdd:smart00563 72 LKEGEWLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
202-377 |
8.36e-12 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 65.42 E-value: 8.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 202 MIRLTGWVLLKLFNsffWNIQIHkgQLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 281
Cdd:COG0204 15 LVRLWARLLLRLLG---VRVRVE--GLENLPADG----PVLIVANHQSWLDILLLLAAL---PRPVRFVAKKELFKIPLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 282 STLIHKLGGFFIRRRldetpDGRKDIlyRALLHghVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssnti 361
Cdd:COG0204 83 GWLLRALGAIPVDRS-----KRRAAL--RALRQ--AVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEA------ 147
|
170
....*....|....*.
gi 1907131786 362 pDILVIPVGISYDRII 377
Cdd:COG0204 148 -GVPIVPVAIDGTERA 162
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
381-610 |
1.82e-11 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 66.77 E-value: 1.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 381 YNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDE 460
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQLSLKLGRVYVRFGEPWSLREFL-------------------------------DE 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 461 HQDlssnesRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIV-ACLLLYRHRqGIHLSTLVEDFFVMKEEVLARDFD 539
Cdd:pfam19277 50 QGD------RPATDAARRRLALQKLAFEVLSRINRVTPVMPTALVgTVLLTLRGR-ALTLSELIRRVEWLLDYIRARGGP 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907131786 540 LGFSGN--SEDVVMHAIQLLGNCVTITHTSRKDE--FFITPSttvpSVFELNFYSNGVLHVFIMEAIIACSIYAV 610
Cdd:pfam19277 123 VAHFGDlrTEEVVDRALDVLGNAGLVTRVDGGPEpvYYIAPE----DHFQASFYRNMTIHLFVERAIVELALLTK 193
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
218-428 |
7.48e-99 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 306.04 E-value: 7.48e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 218 FWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRL 297
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 298 DetpdgrKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRII 377
Cdd:cd07993 81 G------KDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1907131786 378 EGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLE 428
Cdd:cd07993 155 EEELYAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
146-673 |
1.40e-81 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 276.80 E-value: 1.40e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 146 VTENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHk 225
Cdd:COG2937 122 LIERLLRSPAVRKAIEEEAKSKG---------ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD- 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 226 gQLEMVKAATETNlPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLdetpdgRK 305
Cdd:COG2937 192 -NLERLRELAKGH-EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGINLNFWPLGPILRRGGAFFIRRSF------KG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 306 DILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGH-YNGE 384
Cdd:COG2937 264 NKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGsYAKE 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 385 QLGKPKKNESLWSVARGvIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDEHQ-D 463
Cdd:COG2937 344 LRGGEKKKESLGGLLRA-LRKLRRRFGRVYVNFGEPISLSEYL-------------------------------DQHVpD 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 464 LSSNESRNPAdeaFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGI---HLSTLVEDFFVMKEEVLARDFDL 540
Cdd:COG2937 392 WRESEDLRPE---WLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALteaELLAQLDLYLDLLRNVPYSLSVT 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 541 GFSGNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACsiyAVLNKRCsggsa 620
Cdd:COG2937 469 LPELTPEELLEHLLSL--GLIEVEKDGLGDVISIDDEQAV----LLTYYRNNILHLFALPALIAS---ALLANRR----- 534
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1907131786 621 gglgnlISQEQLVRKAASLCYLLSNEGTISLPcQTFYQVCHETVGKFIQYGIL 673
Cdd:COG2937 535 ------ISRAELLELVRLLYPLLKAELFLRWD-AEFEEVLDEELDELVRQGLL 580
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
88-646 |
4.32e-49 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 186.59 E-value: 4.32e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 88 TPQSWERFFNPSI----------PSLGLRNVIYINETHTRhrgwLARRLSYIL---FVQERDVHKG--------MFatsv 146
Cdd:PRK04974 150 VPGRLRKLFAILWlgrdtfvrfsPPVSLRYMADEHGTDKR----IARKLARVArvhFRRQRLAAIGpdlphrqaLF---- 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 147 tENVLSSSRVQEAIAEVAAELNpdgsaqqqsKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHkg 226
Cdd:PRK04974 222 -NKLLASPAIKKAIEDEAKSKK---------ISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVH-- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 227 QLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRrldeTPDGRKd 306
Cdd:PRK04974 290 NAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRR----SFKGNK- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 307 iLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDT-LSSNTIPdILVIPVGISYDRIIEGH-YNGE 384
Cdd:PRK04974 365 -LYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLLQPKTGMLAMTLQAmLRGSRRP-ITLVPVYIGYEHVMEVGtYAKE 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 385 QLGKPKKNESLWSVARgVIRMLRkNYGYVRVDFAQPFSLKEYLEGQsqkpvsAPLSLEQ-ALLPAILPSRPNDVADehqd 463
Cdd:PRK04974 443 LRGAPKEKESLFQVLR-GIRKLR-NFGQGYVNFGEPIPLNDYLNQH------VPEWRESiDPIEEQRPAWLTPAVN---- 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 464 lssnesrnpadeafrrRLIANLAEHIlftaSKSCAIMSTHIVACLLLyRHRQgihlstlvedfFVMKEEVLARDFDLGFS 543
Cdd:PRK04974 511 ----------------NLANQVMVRI----NNAAAANPVNLCALALL-ASRQ-----------RALDREQLIEQLDLYLQ 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 544 ---------------GNSEDVVMHAIQLlgNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 608
Cdd:PRK04974 559 llrnvpyssdttvpeGSGEELIDHALSL--NKFEVEKDTLGDIISLDREQAV----LMTYYRNNILHLFVLPSLIASIVT 632
|
570 580 590
....*....|....*....|....*....|....*...
gi 1907131786 609 AvlNKRcsggsagglgnlISQEQLVRKAASLCYLLSNE 646
Cdd:PRK04974 633 H--NRR------------ISRDELLRIVNALYPFLKAE 656
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
97-604 |
4.29e-47 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 182.00 E-value: 4.29e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 97 NPSIPSLGLRNVIYINETHTRHRGWLArrlsyilfvqerDVHKGMFATSVTeNVLSSSRVQEAIAEVAAElnpDGSAQQQ 176
Cdd:PTZ00374 508 TPLLTRKYFDDVVWTQRVGLTANGWRF------------AATPGLTPESLT-SILAQPSIQRLMTALAKK---EGASEKD 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 177 skaiqkVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATET-NLPLLFLPVHRSHIDYLL 255
Cdd:PTZ00374 572 ------VEARAKAILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAMpRVAVVLLPLHRSYIDFII 645
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 256 LTFILFCHNIKAPYIASGNN-LNIPVFSTLIHKLGGFFIRRRLdetpdgRKDILYRALLHGHVVELLRQQQFLEIFLEGT 334
Cdd:PTZ00374 646 MTYLLAVMGLPLPHVCAGDDfLRMGPIATLMRGSGAFFMRRSF------RDDPLYAALFKEYVRHLVLRRRPLEFFIEGT 719
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 335 RSRSGKTSCARAGLLSVVVDTL--SSNTIPDILVIPVGISYDRIIEGH-YNGEQLGKPKKNESLWSVARGViRMLRKNYG 411
Cdd:PTZ00374 720 RSRTGKTMAPKLGLLKFICDTFyeGQQELDDVLIIPVSLSYDELLETTlYAKEQLGVSKPKENPGNLLRAR-SLLKRRHG 798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 412 YVRVDFAQPFSLKEYLEGQSQKPvsaplsleqallpaiLPSRPND--VADEHQDLSSNESRNPADEAFRRRLIANLAEHI 489
Cdd:PTZ00374 799 KIHVHIGEPVSLRSFKDHPLQCP---------------LPFEPKGeaTTSVCKTLDTTPSIARKSSITPPRVLTNIAWHL 863
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 490 LFTASKSCAIMSTHIVA-----------CLLLYRHRQGIhlsTLVEDFFVMKEEVLARDfdlGFSGNSEDVVMHAIQLLG 558
Cdd:PTZ00374 864 THKLQRNTIITPTALVAavleclgptagAMPLAEVQQGM---TWLRTNIRRRGAALSDD---CANLNPETMVRKALTHLQ 937
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1907131786 559 NCVTIthTSRKDEFFITPSTTVpSVFELNFYSNGVLHVFIMEAIIA 604
Cdd:PTZ00374 938 EFVEI--TDEMSEVIYVRQDVV-TRLGVNICSNQLIHVFMDEAVVA 980
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
146-610 |
7.98e-40 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 158.34 E-value: 7.98e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 146 VTENVLSSSRVQEAIAEVAAELNPDGSAqqqskaiqkVKRKARKILQEMVATVSPGMIRLTGwVLLKLFNS-FFWNIQIH 224
Cdd:PRK03355 184 VKPEILASARFRAGLAKIAAKLGRPPGA---------TVREAGKMLDELVAGWSRVSVDLVS-VLGRLFSRgFDPEIDYD 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 225 KGQLEMVKAATEtNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPdgr 304
Cdd:PRK03355 254 EYELAALRALLE-EHPAVLLFSHRSYIDGLVVPVAMQENRLPPVHVFGGINLSFGPMGPIMRRSGMIFIRRNIGDDP--- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 305 kdiLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIE-GHYNG 383
Cdd:PRK03355 330 ---LYKYVLREYVGYLVEKRFNLSWYIEGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEiGEYAA 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 384 EQLGKPKKNESL-WSVarGVIRML-RKNYGYVRVDFAQPFSLKEYLeGQSQKPVSAPLSLEQALLPAIlpsrpndvadeh 461
Cdd:PRK03355 407 EARGGEKTPEGLrWLY--NYIKAQgERNYGKIYVRFGEPVSMRQYL-GAPHGPLTQDPDAKRLALQKM------------ 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 462 qdlssnesrnpadeAFRRRLIANLAEHILFTASKSCAIMST-----------HIVACLLLYRHRQGIHLSTlvedffvmk 530
Cdd:PRK03355 472 --------------AFEVAWRINQVTPVTATSLVSLLLLGTrgraltldelhHTLQDSLDYLERRQLPVST--------- 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 531 eevlaRDFDLGfsgnSEDVVMHAIQLL--GNCVTITHTSRKDEFFITPSTTVpsvfELNFYSNGVLHVFIMEAIIACSIY 608
Cdd:PRK03355 529 -----SALRLR----DPEGVRAALDALsnGGPVTRVDSGREPVWYIAPDDHL----VAAFYRNSVIHAFLERAIVELALA 595
|
..
gi 1907131786 609 AV 610
Cdd:PRK03355 596 AA 597
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
237-372 |
2.62e-25 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 101.97 E-value: 2.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 237 TNLPLLFLPVHRSHIDYLLLTFILFCHNiKAPYIASGNNL-NIPVFSTLIHKLGGFFIRrrldetpdgRKDILYRALLHG 315
Cdd:pfam01553 12 RGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFID---------RKNRKDAAGTLE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907131786 316 HVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 372
Cdd:pfam01553 82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
241-374 |
3.06e-23 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 95.50 E-value: 3.06e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 241 LLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDEtpdgrkdiLYRALLHgHVVEL 320
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGR--------KARAALR-EAVEL 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1907131786 321 LRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGISYD 374
Cdd:smart00563 72 LKEGEWLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
150-446 |
1.70e-19 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 93.47 E-value: 1.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 150 VLSSSRVQEAIAEVAAEL--NPDGsaqqqskaiqkVKRKARKILQEMVATVSPGMIRltGWvllKLFNSFF---WNIQIH 224
Cdd:PRK11915 38 LLDARWYDERLRALADELgrDPDS-----------VRAEAAGYLREMAASLDERAVQ--AW---RGFSRWLmraYDVLVD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 225 KGQLEMVKAaTETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPdgr 304
Cdd:PRK11915 102 EDQITQLRK-LDRKATLAFAFSHRSYLDGMLLPEVILANRLSPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIP--- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 305 kdiLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIE-GHYNG 383
Cdd:PRK11915 178 ---VYRFVLRAYAAQLVQNHVNLTWSIEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEvEAMTT 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907131786 384 EQLGKPKKNESLwsvaRGVIRMLRKN---YGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALL 446
Cdd:PRK11915 255 EAYGAVKRPEDL----RFLVRLARQQgerLGRAYLDFGEPLPLRKRLQELRADKSGTGSEIERIAL 316
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
202-377 |
8.36e-12 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 65.42 E-value: 8.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 202 MIRLTGWVLLKLFNsffWNIQIHkgQLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 281
Cdd:COG0204 15 LVRLWARLLLRLLG---VRVRVE--GLENLPADG----PVLIVANHQSWLDILLLLAAL---PRPVRFVAKKELFKIPLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 282 STLIHKLGGFFIRRRldetpDGRKDIlyRALLHghVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssnti 361
Cdd:COG0204 83 GWLLRALGAIPVDRS-----KRRAAL--RALRQ--AVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEA------ 147
|
170
....*....|....*.
gi 1907131786 362 pDILVIPVGISYDRII 377
Cdd:COG0204 148 -GVPIVPVAIDGTERA 162
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
381-610 |
1.82e-11 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 66.77 E-value: 1.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 381 YNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLegqsqkpvsaplsleqallpailpsrpndvaDE 460
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQLSLKLGRVYVRFGEPWSLREFL-------------------------------DE 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 461 HQDlssnesRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIV-ACLLLYRHRqGIHLSTLVEDFFVMKEEVLARDFD 539
Cdd:pfam19277 50 QGD------RPATDAARRRLALQKLAFEVLSRINRVTPVMPTALVgTVLLTLRGR-ALTLSELIRRVEWLLDYIRARGGP 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907131786 540 LGFSGN--SEDVVMHAIQLLGNCVTITHTSRKDE--FFITPSttvpSVFELNFYSNGVLHVFIMEAIIACSIYAV 610
Cdd:pfam19277 123 VAHFGDlrTEEVVDRALDVLGNAGLVTRVDGGPEpvYYIAPE----DHFQASFYRNMTIHLFVERAIVELALLTK 193
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
213-373 |
5.92e-10 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 59.21 E-value: 5.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 213 LFNSFFWNIQIHKgqLEMVKAATetnlPLLFLPVHRSHIDYLLLTFILFcHNIKapYIASGNNLNIPVFSTLIHKLGGFF 292
Cdd:cd07989 4 LLRLLGVRVRVEG--LENLPPKG----PVIIVANHQSYLDPLVLGAALP-RPIR--FVAKKELFKIPFLGWLLRLLGAIP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 293 IRRRldetpDGRKDIlyRALLhgHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTlssntipDILVIPVGIS 372
Cdd:cd07989 75 IDRG-----NGRSAR--EALR--EAIEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEA-------GVPIVPVAIS 138
|
.
gi 1907131786 373 Y 373
Cdd:cd07989 139 G 139
|
|
| LPLAT_AAK14816-like |
cd07992 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
203-375 |
4.35e-06 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Pssm-ID: 153254 [Multi-domain] Cd Length: 203 Bit Score: 48.41 E-value: 4.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 203 IRLTGWVLLKLFnsfFWNIQIHKGQLEmvkaatETNLPLLFLPVHR-SHIDYLLLTFILfchNIKAPYIASGNNLNIPVF 281
Cdd:cd07992 1 VRLLSRVILRIY---FRRITVVGRENV------PKDGPVIFLGNHPnALIDPLLLAATL---RRPVRFLAKADLFKNPLI 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 282 STLIHKLGGFFIRRRLDETPDGRKDILYRALLHGhVVELLRQQQFLEIFLEGTrSRSG------KTSCARAGLlsvvvdT 355
Cdd:cd07992 69 GWLLESFGAIPVYRPKDLARGGIGKISNAAVFDA-VGEALKAGGAIGIFPEGG-SHDRprllplKAGAARMAL------E 140
|
170 180
....*....|....*....|
gi 1907131786 356 LSSNTIPDILVIPVGISYDR 375
Cdd:cd07992 141 ALEAGQKDVKIVPVGLNYED 160
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
240-376 |
1.63e-05 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 46.25 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907131786 240 PLLFLPVHRSHIDYLLLTFILFC---HNIKAPYIASGnNLNIPVFStlihKLGGFFIRRRLDEtpDGRKDILYrallhgh 316
Cdd:cd06551 27 PVLFVSNHSSWWDGLILFLLLERglrRDVYGLMDEEL-LERYPFFT----RLGAFSVDRDSPR--SAAKSLKY------- 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907131786 317 VVELLRQ-QQFLEIFLEGTRSRSGKtscaRAGLLSVVVDTLSsnTIPDILVIPVGISYDRI 376
Cdd:cd06551 93 VARLLSKpGSVVWIFPEGTRTRRDK----RPLQFKPGVAHLA--EKAGVPIVPVALRYTFE 147
|
|
| |
