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histone deacetylase complex subunit SAP130 isoform X5 [Mus musculus]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
614-1019
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 549.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 614 A Q GSSPRPSILRKKPAT D G mavrktllppqppdvatprvessmrsasgsprpag AKPK SEV HV SI A T PVTV SL E TISN QN 693
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PDI HV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 694 A EQ P T VAVP P TA Q Q P PPT IP SMI A A A S PPSQP AIA LST I P G A VP VTPP ---- ITTIA A T PT LS A p VGG T PSTVLGPPV PE 769
Cdd:pfam16014 46 S EQ Q T ASAS P PS Q H P AQA IP TIL A P A A PPSQP SVV LST L P A A MA VTPP ipas MANVV A P PT QP A - ASS T AACAVSSVL PE 124
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 770 IK V K E EAEP V D ITR pvs T VPPL ATNTV SP S L AL LA S NLS M P PS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS 849
Cdd:pfam16014 125 IK I K Q EAEP M D TSQ --- S VPPL TPTSI SP A L TS LA N NLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS 201
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 850 A A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S C 929
Cdd:pfam16014 202 A P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T C 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 930 RAQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLD 1009
Cdd:pfam16014 282 RAQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLD 361
410
....*....|
gi 1907130035 1010 HKDRVLKLLN 1019
Cdd:pfam16014 362 HKDRVLKLLN 371
PHA03247 super family
cl33720 large tegument protein UL36; Provisional
34-471
5.14e-08
large tegument protein UL36; Provisional
PHA03247 :Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 57.64
E-value: 5.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 34 G P SSS LPP REEKQE P VVVR P Y P QVQML P AHH AV A S -- AT P vav T APP AHLT P AV P LSFSE glmkpppk PTMPSR P IA P A P 111
Cdd:PHA03247 2550 D P PPP LPP AAPPAA P DRSV P P P RPAPR P SEP AV T S ra RR P --- D APP QSAR P RA P VDDRG -------- DPRGPA P PS P L P 2618
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 112 P S T MSLP P KV P GQVTVTM E SSIPQASAI P VATISGQQGH P SNLHHIM ttnvqmsii R SNAP G PP lh IG AS HL P RGAAAA A 191
Cdd:PHA03247 2619 P D T HAPD P PP P SPSPAAN E PDPHPPPTV P PPERPRDDPA P GRVSRPR --------- R ARRL G RA -- AQ AS SP P QRPRRR A 2687
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 192 VMSS - SKV T TVLR P TSQL P NAAT A QP A VQHLIHQ P IQSRPPVTT S STI P P A VVATVSATRAQS P V - ITTT A AHAADSTLS 269
Cdd:PHA03247 2688 ARPT v GSL T SLAD P PPPP P TPEP A PH A LVSATPL P PGPAAARQA S PAL P A A PAPPAVPAGPAT P G g PARP A RPPTTAGPP 2767
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 270 R P TLSIQHPPSAAISIQ RPA QSRDVTT R IT LPS ------ H PA LGTPKQQLHTM A QKTIFSTGT P VA A ATV AP ILATNTL P 343
Cdd:PHA03247 2768 A P APPAAPAAGPPRRLT RPA VASLSES R ES LPS pwdpad P PA AVLAPAAALPP A ASPAGPLPP P TS A QPT AP PPPPGPP P 2847
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 344 STTTA G SVSHTQAP tsti V TMTM PS H S SH A TAVTTSNI PV AKV vpqqithts P R IQPDYPP E RSS L I P ISGH R ASPNPVA 423
Cdd:PHA03247 2848 PSLPL G GSVAPGGD ---- V RRRP PS R S PA A KPAAPARP PV RRL --------- A R PAVSRST E SFA L P P DQPE R PPQPQAP 2914
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1907130035 424 METRNDNR P SV P V Q F Q YFL P TY P PSAY PLA AH T YTPITSSV S TIRQY P 471
Cdd:PHA03247 2915 PPPQPQPQ P PP P P Q P Q PPP P PP P RPQP PLA PT T DPAGAGEP S GAVPQ P 2962
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
614-1019
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 549.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 614 A Q GSSPRPSILRKKPAT D G mavrktllppqppdvatprvessmrsasgsprpag AKPK SEV HV SI A T PVTV SL E TISN QN 693
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PDI HV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 694 A EQ P T VAVP P TA Q Q P PPT IP SMI A A A S PPSQP AIA LST I P G A VP VTPP ---- ITTIA A T PT LS A p VGG T PSTVLGPPV PE 769
Cdd:pfam16014 46 S EQ Q T ASAS P PS Q H P AQA IP TIL A P A A PPSQP SVV LST L P A A MA VTPP ipas MANVV A P PT QP A - ASS T AACAVSSVL PE 124
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 770 IK V K E EAEP V D ITR pvs T VPPL ATNTV SP S L AL LA S NLS M P PS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS 849
Cdd:pfam16014 125 IK I K Q EAEP M D TSQ --- S VPPL TPTSI SP A L TS LA N NLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS 201
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 850 A A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S C 929
Cdd:pfam16014 202 A P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T C 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 930 RAQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLD 1009
Cdd:pfam16014 282 RAQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLD 361
410
....*....|
gi 1907130035 1010 HKDRVLKLLN 1019
Cdd:pfam16014 362 HKDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
34-471
5.14e-08
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 57.64
E-value: 5.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 34 G P SSS LPP REEKQE P VVVR P Y P QVQML P AHH AV A S -- AT P vav T APP AHLT P AV P LSFSE glmkpppk PTMPSR P IA P A P 111
Cdd:PHA03247 2550 D P PPP LPP AAPPAA P DRSV P P P RPAPR P SEP AV T S ra RR P --- D APP QSAR P RA P VDDRG -------- DPRGPA P PS P L P 2618
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 112 P S T MSLP P KV P GQVTVTM E SSIPQASAI P VATISGQQGH P SNLHHIM ttnvqmsii R SNAP G PP lh IG AS HL P RGAAAA A 191
Cdd:PHA03247 2619 P D T HAPD P PP P SPSPAAN E PDPHPPPTV P PPERPRDDPA P GRVSRPR --------- R ARRL G RA -- AQ AS SP P QRPRRR A 2687
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 192 VMSS - SKV T TVLR P TSQL P NAAT A QP A VQHLIHQ P IQSRPPVTT S STI P P A VVATVSATRAQS P V - ITTT A AHAADSTLS 269
Cdd:PHA03247 2688 ARPT v GSL T SLAD P PPPP P TPEP A PH A LVSATPL P PGPAAARQA S PAL P A A PAPPAVPAGPAT P G g PARP A RPPTTAGPP 2767
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 270 R P TLSIQHPPSAAISIQ RPA QSRDVTT R IT LPS ------ H PA LGTPKQQLHTM A QKTIFSTGT P VA A ATV AP ILATNTL P 343
Cdd:PHA03247 2768 A P APPAAPAAGPPRRLT RPA VASLSES R ES LPS pwdpad P PA AVLAPAAALPP A ASPAGPLPP P TS A QPT AP PPPPGPP P 2847
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 344 STTTA G SVSHTQAP tsti V TMTM PS H S SH A TAVTTSNI PV AKV vpqqithts P R IQPDYPP E RSS L I P ISGH R ASPNPVA 423
Cdd:PHA03247 2848 PSLPL G GSVAPGGD ---- V RRRP PS R S PA A KPAAPARP PV RRL --------- A R PAVSRST E SFA L P P DQPE R PPQPQAP 2914
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1907130035 424 METRNDNR P SV P V Q F Q YFL P TY P PSAY PLA AH T YTPITSSV S TIRQY P 471
Cdd:PHA03247 2915 PPPQPQPQ P PP P P Q P Q PPP P PP P RPQP PLA PT T DPAGAGEP S GAVPQ P 2962
PHA03247
PHA03247 large tegument protein UL36; Provisional
396-865
6.30e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 53.79
E-value: 6.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 396 PRIQPDY PPER SSLI P i SGH R A S PNPV A METRNDNRP S V P V Q fqyfl PTYPPS A Y P laah T YTPI TS SVSTIRQY P VSAQ 475
Cdd:PHA03247 2641 HPPPTVP PPER PRDD P - APG R V S RPRR A RRLGRAAQA S S P P Q ----- RPRRRA A R P ---- T VGSL TS LADPPPPP P TPEP 2710
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 476 AP NSTIT A qtgvgvastvhl N P MQLMTVD A SH A RHIQGIQ PAP ISTQGIQPA P I G tsgiq PA PIGT P GIHSAA P INTQGL 555
Cdd:PHA03247 2711 AP HALVS A ------------ T P LPPGPAA A RQ A SPALPAA PAP PAVPAGPAT P G G ----- PA RPAR P PTTAGP P APAPPA 2773
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 556 Q PAA manq Q P QPEGKTS AV VLADGAT iva NPISN P FSA A PAATT V VQTHSQSASTNT PA QGSS P RP S ILRKK P AT dgmav 635
Cdd:PHA03247 2774 A PAA ---- G P PRRLTRP AV ASLSESR --- ESLPS P WDP A DPPAA V LAPAAALPPAAS PA GPLP P PT S AQPTA P PP ----- 2841
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 636 rktll PP Q PP DVAT P R ---- VESSMRSASGSP R PAG AKP KSEVHVSIATPVTVSLET i S NQNAEQ P TVAVPPTA Q QPP P T 711
Cdd:PHA03247 2842 ----- PP G PP PPSL P L ggsv APGGDVRRRPPS R SPA AKP AAPARPPVRRLARPAVSR - S TESFAL P PDQPERPP Q PQA P P 2915
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 712 I P SMIAAAS PP S QP AIALSTI P GAV P VTP P I T TI A ATP tls A P V G GT P STV LG P ------ P VP EIK V KEE A EPVDI tr P V 785
Cdd:PHA03247 2916 P P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T T DP A GAG --- E P S G AV P QPW LG A lvpgrv A VP RFR V PQP A PSREA -- P A 2990
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 786 S TV PPL a T NTVSPSLALL AS N L SMPPSDL PP GA S prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S AAKS L LVKAEKRKS 863
Cdd:PHA03247 2991 S ST PPL - T GHSLSRVSSW AS S L ALHEETD PP PV S ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD 3064
..
gi 1907130035 864 P P 865
Cdd:PHA03247 3065 P F 3066
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
614-1019
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 549.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 614 A Q GSSPRPSILRKKPAT D G mavrktllppqppdvatprvessmrsasgsprpag AKPK SEV HV SI A T PVTV SL E TISN QN 693
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PDI HV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 694 A EQ P T VAVP P TA Q Q P PPT IP SMI A A A S PPSQP AIA LST I P G A VP VTPP ---- ITTIA A T PT LS A p VGG T PSTVLGPPV PE 769
Cdd:pfam16014 46 S EQ Q T ASAS P PS Q H P AQA IP TIL A P A A PPSQP SVV LST L P A A MA VTPP ipas MANVV A P PT QP A - ASS T AACAVSSVL PE 124
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 770 IK V K E EAEP V D ITR pvs T VPPL ATNTV SP S L AL LA S NLS M P PS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS 849
Cdd:pfam16014 125 IK I K Q EAEP M D TSQ --- S VPPL TPTSI SP A L TS LA N NLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS 201
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 850 A A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S C 929
Cdd:pfam16014 202 A P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T C 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 930 RAQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLD 1009
Cdd:pfam16014 282 RAQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLD 361
410
....*....|
gi 1907130035 1010 HKDRVLKLLN 1019
Cdd:pfam16014 362 HKDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
34-471
5.14e-08
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 57.64
E-value: 5.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 34 G P SSS LPP REEKQE P VVVR P Y P QVQML P AHH AV A S -- AT P vav T APP AHLT P AV P LSFSE glmkpppk PTMPSR P IA P A P 111
Cdd:PHA03247 2550 D P PPP LPP AAPPAA P DRSV P P P RPAPR P SEP AV T S ra RR P --- D APP QSAR P RA P VDDRG -------- DPRGPA P PS P L P 2618
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 112 P S T MSLP P KV P GQVTVTM E SSIPQASAI P VATISGQQGH P SNLHHIM ttnvqmsii R SNAP G PP lh IG AS HL P RGAAAA A 191
Cdd:PHA03247 2619 P D T HAPD P PP P SPSPAAN E PDPHPPPTV P PPERPRDDPA P GRVSRPR --------- R ARRL G RA -- AQ AS SP P QRPRRR A 2687
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 192 VMSS - SKV T TVLR P TSQL P NAAT A QP A VQHLIHQ P IQSRPPVTT S STI P P A VVATVSATRAQS P V - ITTT A AHAADSTLS 269
Cdd:PHA03247 2688 ARPT v GSL T SLAD P PPPP P TPEP A PH A LVSATPL P PGPAAARQA S PAL P A A PAPPAVPAGPAT P G g PARP A RPPTTAGPP 2767
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 270 R P TLSIQHPPSAAISIQ RPA QSRDVTT R IT LPS ------ H PA LGTPKQQLHTM A QKTIFSTGT P VA A ATV AP ILATNTL P 343
Cdd:PHA03247 2768 A P APPAAPAAGPPRRLT RPA VASLSES R ES LPS pwdpad P PA AVLAPAAALPP A ASPAGPLPP P TS A QPT AP PPPPGPP P 2847
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 344 STTTA G SVSHTQAP tsti V TMTM PS H S SH A TAVTTSNI PV AKV vpqqithts P R IQPDYPP E RSS L I P ISGH R ASPNPVA 423
Cdd:PHA03247 2848 PSLPL G GSVAPGGD ---- V RRRP PS R S PA A KPAAPARP PV RRL --------- A R PAVSRST E SFA L P P DQPE R PPQPQAP 2914
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1907130035 424 METRNDNR P SV P V Q F Q YFL P TY P PSAY PLA AH T YTPITSSV S TIRQY P 471
Cdd:PHA03247 2915 PPPQPQPQ P PP P P Q P Q PPP P PP P RPQP PLA PT T DPAGAGEP S GAVPQ P 2962
PHA03247
PHA03247 large tegument protein UL36; Provisional
396-865
6.30e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 53.79
E-value: 6.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 396 PRIQPDY PPER SSLI P i SGH R A S PNPV A METRNDNRP S V P V Q fqyfl PTYPPS A Y P laah T YTPI TS SVSTIRQY P VSAQ 475
Cdd:PHA03247 2641 HPPPTVP PPER PRDD P - APG R V S RPRR A RRLGRAAQA S S P P Q ----- RPRRRA A R P ---- T VGSL TS LADPPPPP P TPEP 2710
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 476 AP NSTIT A qtgvgvastvhl N P MQLMTVD A SH A RHIQGIQ PAP ISTQGIQPA P I G tsgiq PA PIGT P GIHSAA P INTQGL 555
Cdd:PHA03247 2711 AP HALVS A ------------ T P LPPGPAA A RQ A SPALPAA PAP PAVPAGPAT P G G ----- PA RPAR P PTTAGP P APAPPA 2773
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 556 Q PAA manq Q P QPEGKTS AV VLADGAT iva NPISN P FSA A PAATT V VQTHSQSASTNT PA QGSS P RP S ILRKK P AT dgmav 635
Cdd:PHA03247 2774 A PAA ---- G P PRRLTRP AV ASLSESR --- ESLPS P WDP A DPPAA V LAPAAALPPAAS PA GPLP P PT S AQPTA P PP ----- 2841
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 636 rktll PP Q PP DVAT P R ---- VESSMRSASGSP R PAG AKP KSEVHVSIATPVTVSLET i S NQNAEQ P TVAVPPTA Q QPP P T 711
Cdd:PHA03247 2842 ----- PP G PP PPSL P L ggsv APGGDVRRRPPS R SPA AKP AAPARPPVRRLARPAVSR - S TESFAL P PDQPERPP Q PQA P P 2915
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 712 I P SMIAAAS PP S QP AIALSTI P GAV P VTP P I T TI A ATP tls A P V G GT P STV LG P ------ P VP EIK V KEE A EPVDI tr P V 785
Cdd:PHA03247 2916 P P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T T DP A GAG --- E P S G AV P QPW LG A lvpgrv A VP RFR V PQP A PSREA -- P A 2990
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 786 S TV PPL a T NTVSPSLALL AS N L SMPPSDL PP GA S prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S AAKS L LVKAEKRKS 863
Cdd:PHA03247 2991 S ST PPL - T GHSLSRVSSW AS S L ALHEETD PP PV S ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD 3064
..
gi 1907130035 864 P P 865
Cdd:PHA03247 3065 P F 3066
PHA03247
PHA03247 large tegument protein UL36; Provisional
537-828
2.03e-06
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 52.25
E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 537 AP IGTP G i HSAA P INTQG L Q P AAM A NQQ P Q P EGKTS A VVLADGATIVAN P ISN P FSAA pa A TTV V QTHSQSASTNTP AQ G 616
Cdd:PHA03247 2600 AP VDDR G - DPRG P APPSP L P P DTH A PDP P P P SPSPA A NEPDPHPPPTVP P PER P RDDP -- A PGR V SRPRRARRLGRA AQ A 2676
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 617 SSP r P SIL R KKP A TDGMAVRKT L LP P Q PP dvatprvessmrsasgs P RPAGAK P KSE V HVSIAT P VTVS leti SN Q NAEQ 696
Cdd:PHA03247 2677 SSP - P QRP R RRA A RPTVGSLTS L AD P P PP ----------------- P PTPEPA P HAL V SATPLP P GPAA ---- AR Q ASPA 2734
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 697 PTV A VP P T A QQPP P TI P SMI A AASP P SQP A IALSTI P G A V P VT -- P PIT T IA A TPT LS APVGGT PS TVLGPPV P EIKVKE 774
Cdd:PHA03247 2735 LPA A PA P P A VPAG P AT P GGP A RPAR P PTT A GPPAPA P P A A P AA gp P RRL T RP A VAS LS ESRESL PS PWDPADP P AAVLAP 2814
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907130035 775 E A EPVDITR P VSTV PP LATNT - VS P SLALLASNL S M P P - SDLP PG ASP R KK P RKQQ 828
Cdd:PHA03247 2815 A A ALPPAAS P AGPL PP PTSAQ p TA P PPPPGPPPP S L P L g GSVA PG GDV R RR P PSRS 2870
PHA03247
PHA03247 large tegument protein UL36; Provisional
30-318
4.73e-05
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 47.63
E-value: 4.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 30 R EH VG PSS SL --- PP REEKQ EP vvv R P YPQ V QML P AHHAV A S A TPVAVTA P P A HLT PAVP lsfs E G LMK P PPKPTMPSR P 106
Cdd:PHA03247 2689 R PT VG SLT SL adp PP PPPTP EP --- A P HAL V SAT P LPPGP A A A RQASPAL P A A PAP PAVP ---- A G PAT P GGPARPARP P 2761
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 107 IAPA PP S tm SL PP KV P gqvtvtme SSI P QASAIPV A TI S gqqghpsnlhhimttnvq M S II R SNA P G P P lhigash L P RG 186
Cdd:PHA03247 2762 TTAG PP A -- PA PP AA P -------- AAG P PRRLTRP A VA S ------------------ L S ES R ESL P S P W ------- D P AD 2806
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 187 AA AA AVMSSSKVTTVLR P TSQ LP NAAT AQP AVQHLIHQ P IQ sr P PVTTSSTIP P AVVATVSATRAQSPVITTTA A HAADS 266
Cdd:PHA03247 2807 PP AA VLAPAAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PP -- P SLPLGGSVA P GGDVRRRPPSRSPAAKPAAP A RPPVR 2884
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1907130035 267 T L S RP TL S IQHPPS A -- AISIQ RP A Q SRDVTTRITL P SH P ALGT P KQQLHTMAQ 318
Cdd:PHA03247 2885 R L A RP AV S RSTESF A lp PDQPE RP P Q PQAPPPPQPQ P QP P PPPQ P QPPPPPPPR 2938
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
432-808
1.96e-04
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 45.53
E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 432 P SVPV Q FQYFL P TY PP SAYPLA A H T YT P IT S SV S TIR Q - Y P VSA Q A PN S T I - TA QTGVGVAS T VH L N P MQ L MT vdashar 509
Cdd:pfam03154 172 P VLQA Q SGAAS P PS PP PPGTTQ A A T AG P TP S AP S VPP Q g S P ATS Q P PN Q T Q s TA APHTLIQQ T PT L H P QR L PS ------- 244
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 510 hiqgiq P A P ISTQGI QP A P IGTSGI QP A P ig T P GI H SAA P INTQG LQ PAAMAN Q Q P Q P E gktsavvladg ATIVAN P I S N 589
Cdd:pfam03154 245 ------ P H P PLQPMT QP P P PSQVSP QP L P -- Q P SL H GQM P PMPHS LQ TGPSHM Q H P V P P ----------- QPFPLT P Q S S 305
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 590 PFSAA P AATTVVQTH SQ SASTNT P A Q GSSPRPSIL R KK P ATDG - MAVRKTLL PP QP P DVAT P RVE S SMRSA --------- 659
Cdd:pfam03154 306 QSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPA p LSMPHIKP PP TT P IPQL P NPQ S HKHPP hlsgpspfq 385
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 660 -- S GS P R P AGA KP K S EV --- H VSI A T P VTVS L ETI S N Q ---- N A EQ P TVAVPPTAQQ P PPTI P SMIAAASP PSQ PAIAL - 729
Cdd:pfam03154 386 mn S NL P P P PAL KP L S SL sth H PPS A H P PPLQ L MPQ S Q Q lppp P A QP P VLTQSQSLPP P AASH P PTSGLHQV PSQ SPFPQ h 465
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 730 STI PG AV P V ----- T PP IT T IA A T P TLSA P VGGTP S T ------ VLGP P V P EIKV KEEA e PVDITR P V S TV PP LATNTVS P 798
Cdd:pfam03154 466 PFV PG GP P P itpps G PP TS T SS A M P GIQP P SSASV S S sgpvpa AVSC P L P PVQI KEEA - LDEAEE P E S PP PP PRSPSPE P 544
410
....*....|
gi 1907130035 799 SLALLA S NL S 808
Cdd:pfam03154 545 TVVNTP S HA S 554
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
516-825
2.70e-03
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 41.70
E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 516 PA PISTQ G IQPA P IGT S GIQ P A P IGT P G ih S AA P INTQG L QPAAMANQQ P Q P EGKT S AVVLADGATI VA NPISNPFS AA P 595
Cdd:PHA03307 97 PA SPARE G SPTP P GPS S PDP P P P TPP P A -- S PP P SPAPD L SEMLRPVGS P G P PPAA S PPAAGASPAA VA SDAASSRQ AA L 174
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 596 AATTVVQ T HSQSA S TNTPAQG S S P RPS ilrkkpatdgmavrktl LP P Q PP DVAT P RVE S SMRS A SGSP R P A GAKPKSEVH 675
Cdd:PHA03307 175 PLSSPEE T ARAPS S PPAEPPP S T P PAA ----------------- AS P R PP RRSS P ISA S ASSP A PAPG R S A ADDAGASSS 237
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 676 V S IATP vtv S LETISNQNA E Q P tvavpptaqqpp PTI P SM I AAASPPSQPAIALSTIPGAV P VTPPITTIAAT P TL S APV 755
Cdd:PHA03307 238 D S SSSE --- S SGCGWGPEN E C P ------------ LPR P AP I TLPTRIWEASGWNGPSSRPG P ASSSSSPRERS P SP S PSS 302
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 756 G G TPSTVLG P PVPEIKVKEEAEPVDI T RPV S TVPPL A TNTVS PS LALLA S nl SMP P SDLPPGA SPRK K PR 825
Cdd:PHA03307 303 P G SGPAPSS P RASSSSSSSRESSSSS T SSS S ESSRG A AVSPG PS PSRSP S -- PSR P PPPADPS SPRK R PR 370
PRK14950
PRK14950 DNA polymerase III subunits gamma and tau; Provisional
720-840
3.91e-03
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain]
Cd Length: 585
Bit Score: 40.95
E-value: 3.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 720 SPPS Q PAIA L ST I PGAVPVT P PITTIAA T PTLSA PV GG TP STVLG P PVPEIKVKEEA EPV -- DI T R P VSTVP P L A TNTVS 797
Cdd:PRK14950 344 TSYG Q LPLE L AV I EALLVPV P APQPAKP T AAAPS PV RP TP APSTR P KAAAAANIPPK EPV re TA T P P PVPPR P V A PPVPH 423
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1907130035 798 PSLALLASNLSMP P S D LP P GAS P r KK P R K QQHVISTEE GD MM E 840
Cdd:PRK14950 424 TPESAPKLTRAAI P V D EK P KYT P - PA P P K EEEKALIAD GD VL E 465
PHA02732
PHA02732 hypothetical protein; Provisional
216-445
4.11e-03
hypothetical protein; Provisional
Pssm-ID: 165099 [Multi-domain]
Cd Length: 1467
Bit Score: 41.28
E-value: 4.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 216 PA V Q H L IHQPIQSRPPVTTSST -- IPP AVVA ---- TVSATR A QSPVITTTAAHA A DS T LSR P TL S IQHPPSAA IS IQ r P A 289
Cdd:PHA02732 1182 PA P Q L L SSYIPTGSVLYQDPIF ty IPP GIIG msgt NTFTFK A AQLQLSAASSPP A AT T PTP P PS S SSSSSAQS IS TS - P G 1260
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 290 Q SR ----- DV T TR I TLPSH PAL G TPK qqlhtmaqktifs T G TPV A AAT V apilatntlp STTT A GSVSHTQAPT S TIVTM 364
Cdd:PHA02732 1261 Q IQ ivlng ST T IH I NFLFF PAL S TPK ------------- I G QIL A MPI V ---------- NSSG A FISLYVNSAI S ANFNV 1317
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907130035 365 T MPSHS S HA T AVTTSNIPVAKVV P QQITHTSPRIQPDYPP E r S SLIP IS GHRASPNPV A MET RN DNRP S V P VQ F QY F L P T 444
Cdd:PHA02732 1318 T IEYVF S NG T VIKRFTDEPGQIF P LPLINGDEEVIISVEN E - S TTFN IS ANNLGSAQL A LQL RN AISA S L P GP F AF F G P I 1396
.
gi 1907130035 445 Y 445
Cdd:PHA02732 1397 L 1397
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
