|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
2.38e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
:
Pssm-ID: 214823 Cd Length: 183 Bit Score: 143.88 E-value: 2.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138286 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.58e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
:
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.58e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
509-835 |
1.96e-13 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 509 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 588
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 589 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 663
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 664 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 738
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 739 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 809
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138286 810 GESPLLPPRPPQSLQPTPQPSVPTQA 835
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
2.38e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 214823 Cd Length: 183 Bit Score: 143.88 E-value: 2.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138286 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| DENN |
pfam02141 |
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a ... |
1-90 |
4.34e-30 |
|
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a domain which occurs in several proteins involved in Rab- mediated processes or regulation of MAPK signalling pathways.
Pssm-ID: 460461 Cd Length: 186 Bit Score: 117.67 E-value: 4.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNmALD 80
Cdd:pfam02141 98 ILQLFEAALLERRIIFLSSDLARLTLVAEAVVALLYPFVWQHIYIPVLPASLLDVLSAPTPFIIGVHSRYFDLLED-PLD 176
|
90
....*....|
gi 1907138286 81 DVVILNVDTN 90
Cdd:pfam02141 177 DVVLVDLDTG 186
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.58e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.58e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
509-835 |
1.96e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 509 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 588
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 589 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 663
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 664 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 738
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 739 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 809
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138286 810 GESPLLPPRPPQSLQPTPQPSVPTQA 835
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| dDENN |
pfam03455 |
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a ... |
154-205 |
3.68e-07 |
|
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a globular domain. Although not statistically supported it has been suggested that this domain may be similar to members of the Rho/Rac/Cdc42 GEF family. This N-terminal region of DENN folds into a longin module, consisting of a central antiparallel beta-sheet layered between helix H1 and helices H2 and H3 (strands S1-S5). Rab35 interacts with dDENN via residues in helix 1 and in the loop S3-S4.
Pssm-ID: 460925 Cd Length: 48 Bit Score: 47.57 E-value: 3.68e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1907138286 154 FSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGRLDLLNsgeGFSDVFEEE 205
Cdd:pfam03455 1 FDKEAFLKS-LPSDSRPFLSQFLETQMFNEFIEERLESSD---PSIDLFDEE 48
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
510-833 |
3.66e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.45 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 510 SKPSITSPEK------PSALLGTSPALPLRPQNQEGILSPSikeETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAK 583
Cdd:pfam03154 144 TSPSIPSPQDnesdsdSSAQQQILQTQPPVLQAQSGAASPP---SPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 584 LQAAGGPLGDFSSEPlQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPS------PAPGAAGTGsdallalldplnta 657
Cdd:pfam03154 221 TQSTAAPHTLIQQTP-TLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSlhgqmpPMPHSLQTG-------------- 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 658 wsgstiPSHPATPSAATPF-IPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAY----- 731
Cdd:pfam03154 286 ------PSHMQHPVPPQPFpLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHikppp 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 732 ---APSILLSSSGFYAPHRSQPnlSALSMP-------------NLFGQIPMGAHTSPL------QPLGPPAVAPSRIRTL 789
Cdd:pfam03154 360 ttpIPQLPNPQSHKHPPHLSGP--SPFQMNsnlppppalkplsSLSTHHPPSAHPPPLqlmpqsQQLPPPPAQPPVLTQS 437
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1907138286 790 PLARSSARAAEAKQGLALRPGESP-----LLPPRPPQSLQP-TPQPSVPT 833
Cdd:pfam03154 438 QSLPPPAASHPPTSGLHQVPSQSPfpqhpFVPGGPPPITPPsGPPTSTSS 487
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
575-785 |
8.43e-05 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 46.04 E-value: 8.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 575 PPPTARPAKLQAAGGPLGDFSSEPLQMD---RERQAALSPALLSGLLPRAVPQGPTELLQPPSPApGAAGTGSDALLALL 651
Cdd:COG5651 165 TPFTQPPPTITNPGGLLGAQNAGSGNTSsnpGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNT-GFAGTGAAAGAAAA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 652 DPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFGTPPASL 727
Cdd:COG5651 244 AAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAaatgLGLGAGGAAGAAGATG 323
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907138286 728 GPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSR 785
Cdd:COG5651 324 AGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGG 381
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DENN |
smart00799 |
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The ... |
1-90 |
2.38e-39 |
|
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; The DENN domain is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 214823 Cd Length: 183 Bit Score: 143.88 E-value: 2.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD 80
Cdd:smart00799 94 ILQLFAALLLERRIIFTSSNLSTLSAVIEALLALLYPFVWQHIYIPILPASLLDVLSAPTPFIIGVHSSYFEEVKELPDE 173
|
90
....*....|
gi 1907138286 81 DVVILNVDTN 90
Cdd:smart00799 174 DVVVVDLDTG 183
|
|
| DENN |
pfam02141 |
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a ... |
1-90 |
4.34e-30 |
|
DENN (AEX-3) domain; DENN (after differentially expressed in neoplastic vs normal cells) is a domain which occurs in several proteins involved in Rab- mediated processes or regulation of MAPK signalling pathways.
Pssm-ID: 460461 Cd Length: 186 Bit Score: 117.67 E-value: 4.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 1 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNmALD 80
Cdd:pfam02141 98 ILQLFEAALLERRIIFLSSDLARLTLVAEAVVALLYPFVWQHIYIPVLPASLLDVLSAPTPFIIGVHSRYFDLLED-PLD 176
|
90
....*....|
gi 1907138286 81 DVVILNVDTN 90
Cdd:pfam02141 177 DVVLVDLDTG 186
|
|
| dDENN |
smart00801 |
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The ... |
122-188 |
1.58e-16 |
|
Domain always found downstream of DENN domain, found in a variety of signalling proteins; The dDENN domain is part of the tripartite DENN domain. It is always found downstream of the DENN domain itself, which is found in a variety of signalling proteins involved in Rab-mediated processes or regulation of MAPKs signalling pathways. The DENN domain is always encircled on both sides by more divergent domains, called uDENN (for upstream DENN) and dDENN (for downstream DENN). The function of the DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.
Pssm-ID: 129037 Cd Length: 69 Bit Score: 74.63 E-value: 1.58e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 122 GDGVARAFLKAQAAFFGSYRNALK---IEPEEPITFSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGR 188
Cdd:smart00801 1 NDEIREAFLRFFVNLFGGYRNFLRelrKEPGPVITFDKESFLKS-RPSSERPFLSKFLETQMFSQFIEER 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
509-835 |
1.96e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 509 PSKPSITSPEKPSAllGTSPAlPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAG 588
Cdd:PHA03247 2616 PLPPDTHAPDPPPP--SPSPA-ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV 2692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 589 GPLGDFSSEPLQ--MDRERQAALSPALLSGLLPRAVPQG---PTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTI 663
Cdd:PHA03247 2693 GSLTSLADPPPPppTPEPAPHALVSATPLPPGPAAARQAspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 664 PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPfVPSVPVVPPSMPLSSTPARPFGTPPASL--GPAYAPSIL---LS 738
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALPPAASPAGPLPPPTSAQptAPPPPPGPPppsLP 2851
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 739 SSGFYAP----HRSQPNLSALSMPNLFGQIPMG-----AHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQglALRP 809
Cdd:PHA03247 2852 LGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP--PPQP 2929
|
330 340
....*....|....*....|....*.
gi 1907138286 810 GESPLLPPRPPQSLQPTPQPSVPTQA 835
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
509-834 |
4.93e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 70.35 E-value: 4.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 509 PSKPSITSPE-KPSAllgtsPALPLRPQnqegilspsikeeTPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAA 587
Cdd:PHA03247 2577 PSEPAVTSRArRPDA-----PPQSARPR-------------APVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 588 GGPLGDFSSEPLQMD------RERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAW-SG 660
Cdd:PHA03247 2639 DPHPPPTVPPPERPRddpapgRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALvSA 2718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 661 STIPSHPATPSAATPFIPQLSFPPTVTPTPfvQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSS 740
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGP--ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 741 GFYAPHRSQPNLSALSMPNLFGQI------PMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPL 814
Cdd:PHA03247 2797 SLPSPWDPADPPAAVLAPAAALPPaaspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPA 2876
|
330 340
....*....|....*....|
gi 1907138286 815 LPPRPPQSLQPTPQPSVPTQ 834
Cdd:PHA03247 2877 APARPPVRRLARPAVSRSTE 2896
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
505-836 |
6.19e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.42 E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 505 DMAIPSKPSITSPEKPSAllgTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPElgivPPPPTARPAKL 584
Cdd:PHA03247 2697 SLADPPPPPPTPEPAPHA---LVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA----RPPTTAGPPAP 2769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 585 QAAGGPLGdfsSEPLQMDRERQAALSPALLSGLLPRAvPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIP 664
Cdd:PHA03247 2770 APPAAPAA---GPPRRLTRPAVASLSESRESLPSPWD-PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP 2845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 665 SHPATP--SAATPFIPQLSFPPTVTPTPFVQTPLNPfvpsvPVVPPSMPLSSTPARPFGTPPASLGPAYAPSIllsssgf 742
Cdd:PHA03247 2846 PPPSLPlgGSVAPGGDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPPDQPERPPQPQA------- 2913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 743 YAPHRSQPNLSALSMPNLFGQIPmGAHTSPLQPLGPPAVAPSRIRTLPlarssaraaeAKQGLALRPGESPLLPPRPPQS 822
Cdd:PHA03247 2914 PPPPQPQPQPPPPPQPQPPPPPP-PRPQPPLAPTTDPAGAGEPSGAVP----------QPWLGALVPGRVAVPRFRVPQP 2982
|
330
....*....|....
gi 1907138286 823 LQPTPQPSVPTQAR 836
Cdd:PHA03247 2983 APSREAPASSTPPL 2996
|
|
| dDENN |
pfam03455 |
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a ... |
154-205 |
3.68e-07 |
|
dDENN domain; This region is always found associated with pfam02141. It is predicted to form a globular domain. Although not statistically supported it has been suggested that this domain may be similar to members of the Rho/Rac/Cdc42 GEF family. This N-terminal region of DENN folds into a longin module, consisting of a central antiparallel beta-sheet layered between helix H1 and helices H2 and H3 (strands S1-S5). Rab35 interacts with dDENN via residues in helix 1 and in the loop S3-S4.
Pssm-ID: 460925 Cd Length: 48 Bit Score: 47.57 E-value: 3.68e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1907138286 154 FSEEAFVSHyRSGAMKQFLQNATQLQLFKQFIDGRLDLLNsgeGFSDVFEEE 205
Cdd:pfam03455 1 FDKEAFLKS-LPSDSRPFLSQFLETQMFNEFIEERLESSD---PSIDLFDEE 48
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
530-776 |
2.54e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 530 LPLRPQNQEGILSPsikeetpiPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAGgplgdfSSEPLQMDRERQAAL 609
Cdd:PRK12323 361 LAFRPGQSGGGAGP--------ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPA------AAAAARAVAAAPARR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 610 SPAL--LSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVT 687
Cdd:PRK12323 427 SPAPeaLAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 688 PTPFVQtPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSSGFYAPHRsqPNLSALSMPNLF-GQIPM 766
Cdd:PRK12323 507 ASPAPA-QPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRP--PRASASGLPDMFdGDWPA 583
|
250
....*....|
gi 1907138286 767 GAHTSPLQPL 776
Cdd:PRK12323 584 LAARLPVRGL 593
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
500-843 |
2.76e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 500 SLGQDDMAIPSKPSITSPekpSALLGTSPALPLRPQNQEGI--LSPSIKEETPIPTPGSITIPRPqgrKTPELGIVPPPP 577
Cdd:PHA03247 2500 GGGPPDPDAPPAPSRLAP---AILPDEPVGEPVHPRMLTWIrgLEELASDDAGDPPPPLPPAAPP---AAPDRSVPPPRP 2573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 578 TARPAklQAAGGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGT----GSDALLALLDP 653
Cdd:PHA03247 2574 APRPS--EPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANepdpHPPPTVPPPER 2651
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 654 LNTAWSGSTI--------PSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPA 725
Cdd:PHA03247 2652 PRDDPAPGRVsrprrarrLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 726 SLGPAYAPSILLSSSGFYAP--HRSQPNLSALSMPNLfGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQ 803
Cdd:PHA03247 2732 SPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPA-PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA 2810
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1907138286 804 GLALRPGESPLLPPRPPQSLQPTPQPSVPTQARDPFEDLL 843
Cdd:PHA03247 2811 VLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
510-833 |
3.66e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.45 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 510 SKPSITSPEK------PSALLGTSPALPLRPQNQEGILSPSikeETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAK 583
Cdd:pfam03154 144 TSPSIPSPQDnesdsdSSAQQQILQTQPPVLQAQSGAASPP---SPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 584 LQAAGGPLGDFSSEPlQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPS------PAPGAAGTGsdallalldplnta 657
Cdd:pfam03154 221 TQSTAAPHTLIQQTP-TLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSlhgqmpPMPHSLQTG-------------- 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 658 wsgstiPSHPATPSAATPF-IPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAY----- 731
Cdd:pfam03154 286 ------PSHMQHPVPPQPFpLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHikppp 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 732 ---APSILLSSSGFYAPHRSQPnlSALSMP-------------NLFGQIPMGAHTSPL------QPLGPPAVAPSRIRTL 789
Cdd:pfam03154 360 ttpIPQLPNPQSHKHPPHLSGP--SPFQMNsnlppppalkplsSLSTHHPPSAHPPPLqlmpqsQQLPPPPAQPPVLTQS 437
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1907138286 790 PLARSSARAAEAKQGLALRPGESP-----LLPPRPPQSLQP-TPQPSVPT 833
Cdd:pfam03154 438 QSLPPPAASHPPTSGLHQVPSQSPfpqhpFVPGGPPPITPPsGPPTSTSS 487
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
575-785 |
8.43e-05 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 46.04 E-value: 8.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 575 PPPTARPAKLQAAGGPLGDFSSEPLQMD---RERQAALSPALLSGLLPRAVPQGPTELLQPPSPApGAAGTGSDALLALL 651
Cdd:COG5651 165 TPFTQPPPTITNPGGLLGAQNAGSGNTSsnpGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNT-GFAGTGAAAGAAAA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 652 DPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFGTPPASL 727
Cdd:COG5651 244 AAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAaatgLGLGAGGAAGAAGATG 323
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907138286 728 GPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSR 785
Cdd:COG5651 324 AGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGG 381
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
508-831 |
8.72e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.30 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 508 IPSKPSITSPEKPSALLGTSPALPLRPQNQEGILS-PSIKEETPIPTPGSITIPRPQGRKTPelgiVPPPPTARPAKLQA 586
Cdd:pfam03154 231 IQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPlPQPSLHGQMPPMPHSLQTGPSHMQHP----VPPQPFPLTPQSSQ 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 587 AGGPLGDFSSEPLQM-DRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLdplntawsgstipS 665
Cdd:pfam03154 307 SQVPPGPSPAAPGQSqQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH-------------K 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 666 HPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMP----LSSTPARPFG-------TPPASLGPAYAPS 734
Cdd:pfam03154 374 HPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPqsqqLPPPPAQPPVltqsqslPPPAASHPPTSGL 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 735 ILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPlgPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPL 814
Cdd:pfam03154 454 HQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPE 531
|
330
....*....|....*..
gi 1907138286 815 LPPRPPQSlqPTPQPSV 831
Cdd:pfam03154 532 SPPPPPRS--PSPEPTV 546
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
506-850 |
1.85e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 506 MAIPSKPSITSPEKPSALLGTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQ 585
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 586 AAG--GPLGDFSSEPLQMDRERQAA-----LSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAW 658
Cdd:PHA03307 140 PVGspGPPPAASPPAAGASPAAVASdaassRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASS 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 659 SGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPL---NPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSI 735
Cdd:PHA03307 220 PAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLprpAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 736 LLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPlarssaraaeakqglalrPGESPLL 815
Cdd:PHA03307 300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPS------------------RPPPPAD 361
|
330 340 350
....*....|....*....|....*....|....*
gi 1907138286 816 PPRPPQSlqPTPQPSVPTQARDPFEDLLRKTKQDV 850
Cdd:PHA03307 362 PSSPRKR--PRPSRAPSSPAASAGRPTRRRARAAV 394
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
508-778 |
6.91e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.38 E-value: 6.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 508 IPSKPsiTSPEKPSALLGTSPAlPLRPQNQEGILSPSIKEetpiPTPGSITIPRPQGRKTPELGIVPPpptARPAKLQAA 587
Cdd:PLN03209 323 IPSQR--VPPKESDAADGPKPV-PTKPVTPEAPSPPIEEE----PPQPKAVVPRPLSPYTAYEDLKPP---TSPIPTPPS 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 588 GGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPApgaagtgsdallalldplnTAWSGSTIPSHP 667
Cdd:PLN03209 393 SSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPY-------------------ARYEDLKPPTSP 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 668 aTPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAyapsillSSSGFYAPHR 747
Cdd:PLN03209 454 -SPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPA-------APVGKVAPSS 525
|
250 260 270
....*....|....*....|....*....|..
gi 1907138286 748 SQPNLSALSMPNLFGQIPMGAHTSPLQ-PLGP 778
Cdd:PLN03209 526 TNEVVKVGNSAPPTALADEQHHAQPKPrPLSP 557
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
355-675 |
8.58e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 39.77 E-value: 8.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 355 LSEDSSDEECRREEAPSTGFT--ESLLFSAPFEWPQPYRtlkESDSAEGDETESPEQLVREPWGPTPAPPDRAASIDLLE 432
Cdd:PHA03307 10 LIEAAAEGGEFFPRPPATPGDaaDDLLSGSQGQLVSDSA---ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 433 DVFSSLDVEAPLQPLGQAKSLEDLRAPKDLREQPGSfdyqrLDLCRSERGLSMAAALKLAHPYTklwSLGQDDMAIPSKP 512
Cdd:PHA03307 87 TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPP-----PASPPPSPAPDLSEMLRPVGSPG---PPPAASPPAAGAS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 513 SITSPEKPSALLGTSPALPLRPQNQEGILSPSikEETPIPTPGSITIPRPQGRKTPeLGIVPPPPTARPAKLQAAGGPLG 592
Cdd:PHA03307 159 PAAVASDAASSRQAALPLSSPEETARAPSSPP--AEPPPSTPPAAASPRPPRRSSP-ISASASSPAPAPGRSAADDAGAS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907138286 593 DFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLdplntawSGSTIPSHPATPSA 672
Cdd:PHA03307 236 SSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRER-------SPSPSPSSPGSGPA 308
|
...
gi 1907138286 673 ATP 675
Cdd:PHA03307 309 PSS 311
|
|
| |
