|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
507-893 |
5.71e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 81.14 E-value: 5.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 507 PSTPKRQSTPKPPRVKPAPEPETRPS--AQTTKAPRKTKKPGHHRLRRPKTTR-SPEVPKSKPALEPATVTPEILVPKIV 583
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPAPRPSepAVTSRARRPDAPPQSARPRAPVDDRgDPRGPAPPSPLPPDTHAPDPPPPSPS 2632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 584 PKPPQ----KPKATRRPEVPQVKPAHEPVTFGSEAPALAIVTTTDIEPVITRTKA------SVTTLAPKPPRPRTHRQRT 653
Cdd:PHA03247 2633 PAANEpdphPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgSLTSLADPPPPPPTPEPAP 2712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 654 KYKTTQSPKIP-------HSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSLEPfIITEAPGTTL 726
Cdd:PHA03247 2713 HALVSATPLPPgpaaarqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASL 2791
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 727 VPKLPQQPD----YPHPKPKTTRSPAASPTELVPTPVFEPVTPLKEDPVTTIVPitdLERVTDLETPVA----FRTEAPG 798
Cdd:PHA03247 2792 SESRESLPSpwdpADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP---PPPSLPLGGSVApggdVRRRPPS 2868
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 799 TTLASKISQRTHRPRPRPRPRPRPRPRPKATLSPQAPETKTVPAVVLEPVTLRPEVQVTTLAPQKTQKKHRPSPKPKPVP 878
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
|
410
....*....|....*
gi 1907118362 879 SPEVTESKPVLPRVR 893
Cdd:PHA03247 2949 PAGAGEPSGAVPQPW 2963
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1446-1537 |
3.59e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 3.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1446 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQITNQTFSTVENLKPDTSYEFQVKPKNP 1523
Cdd:cd00063 2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 1907118362 1524 LGEGPASNTVAFST 1537
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
981-1392 |
2.77e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.18 E-value: 2.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 981 RTRRPHPRPK-TTASTGVSESKSAPTELQSLVLKPVTSPSLEIIQSQSVSddlelvAFSTESPQKTIAPAETDYVDTKEP 1059
Cdd:PHA03247 2585 RARRPDAPPQsARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPA------ANEPDPHPPPTVPPPERPRDDPAP 2658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1060 LRLEEPR-TEVVDSLTYVSEPPE----TTIETSPLSSQSIIIPRPDEPQTEPAPRQTTSMPPKLKTPHSRMPAKEPVPKE 1134
Cdd:PHA03247 2659 GRVSRPRrARRLGRAAQASSPPQrprrRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAA 2738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1135 PLhTTSKPKMPPSPEVADTTSVPKDERLSLKPDPEVTHSETAPletRGIPLIPVISPRPSQEELQTAMEETDQS------ 1208
Cdd:PHA03247 2739 PA-PPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP---RRLTRPAVASLSESRESLPSPWDPADPPaavlap 2814
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1209 TQELFTTKIPRTTELAKTTQAPhrlhTAPVRPRIPGRPH---------GRPALNKTTTRPDKTKPRGTSHKNGVGTGTKQ 1279
Cdd:PHA03247 2815 AAALPPAASPAGPLPPPTSAQP----TAPPPPPGPPPPSlplggsvapGGDVRRRPPSRSPAAKPAAPARPPVRRLARPA 2890
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1280 APKPPSPGRNASVDSHATRKPGSVSGTRRPPIPHRHSSTRPvSPERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHP 1359
Cdd:PHA03247 2891 VSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP-PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969
|
410 420 430
....*....|....*....|....*....|...
gi 1907118362 1360 IGTATARPGAEQKEPTAPASEEEFGTTTDFSSS 1392
Cdd:PHA03247 2970 GRVAVPRFRVPQPAPSREAPASSTPPLTGHSLS 3002
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1447-1527 |
1.10e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 51.08 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1447 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQITNQTFS-TVENLKPDTSYEFQVKPKNPL 1524
Cdd:smart00060 3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1907118362 1525 GEG 1527
Cdd:smart00060 81 GEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1447-1530 |
1.47e-06 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 47.79 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1447 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQITNQTFS-TVENLKPDTSYEFQVKPKNP 1523
Cdd:pfam00041 2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78
|
....*..
gi 1907118362 1524 LGEGPAS 1530
Cdd:pfam00041 79 GGEGPPS 85
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
384-758 |
1.05e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.07 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 384 PEFPEAKTAFPLEKPRGSWASSEEPWVVPGAKTSEDSRVVQPQTATYDVISSSTTSDETEIEIHTATRDPILDSV----- 458
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPhpplq 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 459 -------PPKTSRTAEQPRATLAPIEALFESrnveIFTSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPE----- 526
Cdd:pfam03154 251 pmtqpppPSQVSPQPLPQPSLHGQMPPMPHS----LQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSqqrih 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 527 -PETRPSAQTTKAPRKTKKP----GHHRLRRPKTTRSPEVPKSKPALEPATVT---PEILVPKIVPKPPQKPKATRRPEV 598
Cdd:pfam03154 327 tPPSQSQLQSQQPPREQPLPpaplSMPHIKPPPTTPIPQLPNPQSHKHPPHLSgpsPFQMNSNLPPPPALKPLSSLSTHH 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 599 PqvkPAHEPVTFGSEAPALAIVTTTDIEPVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEP 678
Cdd:pfam03154 407 P---PSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPT 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 679 PLASTTKKVRRPRPKPQTTPHPeVPHTilvPATSLEPFIITEAPgttlvPKLPQQPDYPHPKPkttRSPAASPTeLVPTP 758
Cdd:pfam03154 484 STSSAMPGIQPPSSASVSSSGP-VPAA---VSCPLPPVQIKEEA-----LDEAEEPESPPPPP---RSPSPEPT-VVNTP 550
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1431-1542 |
1.40e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 46.53 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1431 PTEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQITNQTFSTVENLKP 1510
Cdd:COG3401 220 PSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATVTTTSYTDTGLTN 294
|
90 100 110
....*....|....*....|....*....|...
gi 1907118362 1511 DTSYEFQVKPKNPLG-EGPASNTVAFSTESADP 1542
Cdd:COG3401 295 GTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
116-195 |
2.26e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 41.63 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPSD-RFYTIRYREKDKEKKWIFQLCPATET--IVENLKPNTVYEF 192
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71
|
...
gi 1907118362 193 GVK 195
Cdd:pfam00041 72 RVQ 74
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
114-195 |
3.05e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.06 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 114 PRKPLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPSDRFYTIRYREKDKEKKWIFQLCPA----TETIVENLKPNTV 189
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTE 69
|
....*.
gi 1907118362 190 YEFGVK 195
Cdd:smart00060 70 YEFRVR 75
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
114-195 |
3.26e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 41.33 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 114 PRKPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpsdrFYTIRYREKDKE--KKWIFQLCPATETIVENLKPNTVYE 191
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYE 71
|
....
gi 1907118362 192 FGVK 195
Cdd:cd00063 72 FRVR 75
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
491-703 |
7.28e-04 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 44.37 E-value: 7.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAAPQ---QTTSIPSTPKRQSTPKPPRVKPAPEPETrPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPA 567
Cdd:NF033839 286 EPGNKKPSAPKpgmQPSPQPEKKEVKPEPETPKPEVKPQLEK-PKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPE 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 568 LEPATVTPEilvpKIVPKPPQKPKATRRPEVPQVKPAHEPvtfGSEAPalaivtTTDIEPVITRTKASVTTlAPKPPRPR 647
Cdd:NF033839 365 VKPQPEKPK----PEVKPQPETPKPEVKPQPEKPKPEVKP---QPEKP------KPEVKPQPEKPKPEVKP-QPEKPKPE 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907118362 648 THRQRTKYKTTQSPKIPHSKPAdlgpITSEPPLASTTKKVRRPRPKPQTTPHPEVP 703
Cdd:NF033839 431 VKPQPEKPKPEVKPQPEKPKPE----VKPQPETPKPEVKPQPEKPKPEVKPQPEKP 482
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
950-1322 |
3.47e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 42.21 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 950 VPATVVLATALTPVTLRTKAPKTTTLAPNVQRTRRPHPrpktTASTGVSESKSAPTELQSlvlKPVTSPSleiIQSQSVS 1029
Cdd:pfam05109 405 ITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAP----NTTTGLPSSTHVPTNLTA---PASTGPT---VSTADVT 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1030 DDLELVAFSTESPQkTIAPAETDYVDTKEPLRLEEPRTEVVDSLTYVSEP-PETTIETSPLSSQSIIIPRPDEPQTEPAP 1108
Cdd:pfam05109 475 SPTPAGTTSGASPV-TPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPtPAVTTPTPNATSPTLGKTSPTSAVTTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1109 RQTTSMPP-KLKTPHSRMPAKEPVPKEPLHTTSKPKmPPSPEVADTTSVPKDERLSL----------KPDPEVTHSETAP 1177
Cdd:pfam05109 554 NATSPTPAvTTPTPNATIPTLGKTSPTSAVTTPTPN-ATSPTVGETSPQANTTNHTLggtsstpvvtSPPKNATSAVTTG 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1178 LETRGIPLIPVISPRPS--QEELQTAMEETDQSTQELFTTKIP----RTTELAKTTQAPHRLHTAPVRPRiPGRPH--GR 1249
Cdd:pfam05109 633 QHNITSSSTSSMSLRPSsiSETLSPSTSDNSTSHMPLLTSAHPtggeNITQVTPASTSTHHVSTSSPAPR-PGTTSqaSG 711
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907118362 1250 PALNKTTTRPDKTK-PRGTSHKNGVgtgtkqAPKPPSPGRNASVDSHAT-RKPGSVSGTRRPPIPHRHSSTRPVS 1322
Cdd:pfam05109 712 PGNSSTSTKPGEVNvTKGTPPKNAT------SPQAPSGQKTAVPTVTSTgGKANSTTGGKHTTGHGARTSTEPTT 780
|
|
| Not5 |
COG5665 |
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]; |
428-770 |
6.09e-03 |
|
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription];
Pssm-ID: 444384 [Multi-domain] Cd Length: 874 Bit Score: 41.57 E-value: 6.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 428 ATYDVISSSTTSDETEIEIHTATR-------DPILDSVPPKTSRTAEQPRATLAPIEALFESRNVEIFTSPEVR------ 494
Cdd:COG5665 208 STPQAFNASATSGRSQHIVQAAKRvgvewwgDPSLLATPPATPATEEKSSQQPKSQPTSPSGGTTPPSTNQLTTsntpts 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 495 --------PTTAAPQQTTSIPSTPKRQSTPKPPRV--KPAPEPETRPSAQTTKAPRKTKKPGHhrlrRPKTTRSPEVPKS 564
Cdd:COG5665 288 takaqpqpPTKKQPAKEPPSDTASGNPSAPSVLINsdSPTSEDPATASVPTTEETTAFTTPSS----VPSTPAEKDTPAT 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 565 KPALEPATVTPEILV-PKIVPKPPQKPKATrrpevpqvkpAHEPVTFGSEAPalaivtttdiepvitrtkASVTTLAPKP 643
Cdd:COG5665 364 DLATPVSPTPPETSVdKKVSPDSATSSTKS----------EKEGGTASSPMP------------------PNIAIGAKDD 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 644 PRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEPPLAS--------TTKKVRRPRPKPQTTPHPEVPHTILVPATSLEP 715
Cdd:COG5665 416 VDATDPSQEAKEYTKNAPMTPEADSAPESSVRTEASPSAgsdlepenTTLRDPAPNAIPPPEDPSTIGRLSSGDKLANET 495
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 716 FIITEAPGTTLVPKLPQQ--PDYPHPKPKTT---RSPAASPTELVPTPVFEPVTPLKEDP 770
Cdd:COG5665 496 GPPVIRRDSTPSSTADQSivGVLAFGLDQRTqaeISVEAASRSNPLLNSQVKSFPLGKRS 555
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
507-893 |
5.71e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 81.14 E-value: 5.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 507 PSTPKRQSTPKPPRVKPAPEPETRPS--AQTTKAPRKTKKPGHHRLRRPKTTR-SPEVPKSKPALEPATVTPEILVPKIV 583
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPAPRPSepAVTSRARRPDAPPQSARPRAPVDDRgDPRGPAPPSPLPPDTHAPDPPPPSPS 2632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 584 PKPPQ----KPKATRRPEVPQVKPAHEPVTFGSEAPALAIVTTTDIEPVITRTKA------SVTTLAPKPPRPRTHRQRT 653
Cdd:PHA03247 2633 PAANEpdphPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgSLTSLADPPPPPPTPEPAP 2712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 654 KYKTTQSPKIP-------HSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSLEPfIITEAPGTTL 726
Cdd:PHA03247 2713 HALVSATPLPPgpaaarqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASL 2791
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 727 VPKLPQQPD----YPHPKPKTTRSPAASPTELVPTPVFEPVTPLKEDPVTTIVPitdLERVTDLETPVA----FRTEAPG 798
Cdd:PHA03247 2792 SESRESLPSpwdpADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP---PPPSLPLGGSVApggdVRRRPPS 2868
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 799 TTLASKISQRTHRPRPRPRPRPRPRPRPKATLSPQAPETKTVPAVVLEPVTLRPEVQVTTLAPQKTQKKHRPSPKPKPVP 878
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
|
410
....*....|....*
gi 1907118362 879 SPEVTESKPVLPRVR 893
Cdd:PHA03247 2949 PAGAGEPSGAVPQPW 2963
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
509-776 |
2.73e-12 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 72.03 E-value: 2.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 509 TPKRQSTPKPPRV-----KPAPEPETRPSA--QTTKAPRKTKKPGHHRlrRPKTTRSPEVPKS--KPALEPATVTPEILV 579
Cdd:PTZ00449 542 EPKEGGKPGETKEgevgkKPGPAKEHKPSKipTLSKKPEFPKDPKHPK--DPEEPKKPKRPRSaqRPTRPKSPKLPELLD 619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 580 PKIVPKPPQKPKATRRPevpqvkpahepvtfgseapalaivtttdiepvitrtkasvttlaPKPPRPRTHRQRTKYKTTQ 659
Cdd:PTZ00449 620 IPKSPKRPESPKSPKRP--------------------------------------------PPPQRPSSPERPEGPKIIK 655
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 660 SPKIPHSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSLEPFIITEAPgTTLVPKLPQQPDYPHP 739
Cdd:PTZ00449 656 SPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTP-RPLPPKLPRDEEFPFE 734
|
250 260 270
....*....|....*....|....*....|....*..
gi 1907118362 740 KPKTTRSPAASPTELVPTPVfEPVTPLKEDPVTTIVP 776
Cdd:PTZ00449 735 PIGDPDAEQPDDIEFFTPPE-EERTFFHETPADTPLP 770
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
448-743 |
3.24e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 65.73 E-value: 3.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 448 TATRDPILDSVPPKTSRTAEQPRATLAPIEALFESRNVEIFTSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEP 527
Cdd:PHA03247 2696 TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 528 ETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKP-ALEPATVTPEILVP---KIVPKPPQKPKATRRPEVPQVKP 603
Cdd:PHA03247 2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPaAALPPAASPAGPLPpptSAQPTAPPPPPGPPPPSLPLGGS 2855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 604 AHEPVTFGSEAPALAIVTTtdiepVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEPPLAST 683
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAK-----PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907118362 684 TKKVRRPRPKPQTTPHPEVPHTILVPATSLEPFIITEAPGTTLVPKL---PQQPDYPHPKPKT 743
Cdd:PHA03247 2931 PPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFrvpQPAPSREAPASST 2993
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1446-1537 |
3.59e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 3.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1446 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQITNQTFSTVENLKPDTSYEFQVKPKNP 1523
Cdd:cd00063 2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 1907118362 1524 LGEGPASNTVAFST 1537
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
524-1127 |
8.18e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 61.11 E-value: 8.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 524 APEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKskPALEPATVTPEILVPKIV-------------------P 584
Cdd:PHA03247 2477 APVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLA--PAILPDEPVGEPVHPRMLtwirgleelasddagdpppP 2554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 585 KPPQKPKATRRPEVPQVKPAHEPvtfgSEAPALAIVTTTDIEPVITRTKASV-------TTLAPKPPRPRTHR------- 650
Cdd:PHA03247 2555 LPPAAPPAAPDRSVPPPRPAPRP----SEPAVTSRARRPDAPPQSARPRAPVddrgdprGPAPPSPLPPDTHApdpppps 2630
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 651 QRTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSlepfiiteAPGTTLVpKL 730
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTV--------GSLTSLA-DP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 731 PQQPDYPHPKPKTTRSpaASPTELVPTPVFEPVTPLKEDPVTTIVPITDLERVTDLETPVAFRTEAPGTTLASKISQRTH 810
Cdd:PHA03247 2702 PPPPPTPEPAPHALVS--ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 811 RPRPRPRPRPRPRPRPKATLSPQAPETKTVPAVVLEPVTLRPEVQVTTLAPQKTQKKHRPSPKPKPVPSPEVTESKpVLP 890
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS-VAP 2858
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 891 rvREPVTLRTETWVTTKAPKTPKRTRRPRPKPQTTPTPEtpltkpvaatdlEPSALSTEVPATVVLATALTPVTLRTKAP 970
Cdd:PHA03247 2859 --GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRST------------ESFALPPDQPERPPQPQAPPPPQPQPQPP 2924
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 971 KTTTLAPNVQRTRRPHPRPKTTAST-GVSESKSAPTELQSLVLKPVTSPSLEIIQSQSvSDDLELVAFSTESPQKTIAPA 1049
Cdd:PHA03247 2925 PPPQPQPPPPPPPRPQPPLAPTTDPaGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP-APSREAPASSTPPLTGHSLSR 3003
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907118362 1050 ETDYVDTkepLRLEEPRTEVVDSLTYVSEPPETTIETSPLSSQSIIIPRPDEPQTEPAPRQTTSmpPKLKTPHSRMPA 1127
Cdd:PHA03247 3004 VSSWASS---LALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHD--PFAHEPDPATPE 3076
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
981-1392 |
2.77e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.18 E-value: 2.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 981 RTRRPHPRPK-TTASTGVSESKSAPTELQSLVLKPVTSPSLEIIQSQSVSddlelvAFSTESPQKTIAPAETDYVDTKEP 1059
Cdd:PHA03247 2585 RARRPDAPPQsARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPA------ANEPDPHPPPTVPPPERPRDDPAP 2658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1060 LRLEEPR-TEVVDSLTYVSEPPE----TTIETSPLSSQSIIIPRPDEPQTEPAPRQTTSMPPKLKTPHSRMPAKEPVPKE 1134
Cdd:PHA03247 2659 GRVSRPRrARRLGRAAQASSPPQrprrRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAA 2738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1135 PLhTTSKPKMPPSPEVADTTSVPKDERLSLKPDPEVTHSETAPletRGIPLIPVISPRPSQEELQTAMEETDQS------ 1208
Cdd:PHA03247 2739 PA-PPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP---RRLTRPAVASLSESRESLPSPWDPADPPaavlap 2814
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1209 TQELFTTKIPRTTELAKTTQAPhrlhTAPVRPRIPGRPH---------GRPALNKTTTRPDKTKPRGTSHKNGVGTGTKQ 1279
Cdd:PHA03247 2815 AAALPPAASPAGPLPPPTSAQP----TAPPPPPGPPPPSlplggsvapGGDVRRRPPSRSPAAKPAAPARPPVRRLARPA 2890
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1280 APKPPSPGRNASVDSHATRKPGSVSGTRRPPIPHRHSSTRPvSPERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHP 1359
Cdd:PHA03247 2891 VSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP-PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969
|
410 420 430
....*....|....*....|....*....|...
gi 1907118362 1360 IGTATARPGAEQKEPTAPASEEEFGTTTDFSSS 1392
Cdd:PHA03247 2970 GRVAVPRFRVPQPAPSREAPASSTPPLTGHSLS 3002
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
545-1184 |
7.15e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 7.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 545 PGHHRLRRPKTTRSPEVPKSKPalEPATVTPEilvPKIVPKPPQKPKATRRPEVPQVKPAHEPV-------------TFG 611
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAAP--DPGGGGPP---DPDAPPAPSRLAPAILPDEPVGEPVHPRMltwirgleelasdDAG 2549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 612 SEAPALAivttTDIEPVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGPitsepplasttkkvrrPR 691
Cdd:PHA03247 2550 DPPPPLP----PAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGD----------------PR 2609
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 692 PKPQTTPHPEVPHTILVPATSLEPFIITEAPGTTLVPKLPQQPDYPHPKPKTTRSPAASPTELVPTPVFEPVTPLKEDPV 771
Cdd:PHA03247 2610 GPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR 2689
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 772 TTIVPITDLERvtdletpvafrTEAPGTTLASKISQRTHRPRPRPRPRPRPRPRPKATLSPQAPETKTVPAVVLEPVtlR 851
Cdd:PHA03247 2690 PTVGSLTSLAD-----------PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA--R 2756
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 852 PEVQVTTLAPqktqkkhrpspkpkpvpspevteSKPVLPRVREPVTLRTETwVTTKAPKTPKRTRRPRPKPQTTPTPETP 931
Cdd:PHA03247 2757 PARPPTTAGP-----------------------PAPAPPAAPAAGPPRRLT-RPAVASLSESRESLPSPWDPADPPAAVL 2812
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 932 LTKPVAATDLEPSALSTEVPATVVLATALTPVTLRTKAPKTTTLAPNVQRTRRPHPRPKTTASTGVSESKSaptelqSLV 1011
Cdd:PHA03247 2813 APAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPV------RRL 2886
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1012 LKPVTSPSLEiiqsqsvsdDLELVAFSTESPQKTIAPAETDYVDTKEPLRLEEPrtevvdsltyvsEPPETTIETSPLSS 1091
Cdd:PHA03247 2887 ARPAVSRSTE---------SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP------------PPPPPPRPQPPLAP 2945
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1092 QSIIIPRPDEPQTEPAPRQTTSMPPKLKTPHSRMPAKEPVPKEPLHTTSKPKMPPSPEVADTTSvpkderlSLKPDPEVT 1171
Cdd:PHA03247 2946 TTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS-------SLALHEETD 3018
|
650
....*....|...
gi 1907118362 1172 HSETAPLETRGIP 1184
Cdd:PHA03247 3019 PPPVSLKQTLWPP 3031
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
494-844 |
1.08e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 57.01 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 494 RPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEpetrpSAQTTKAPRKTKKPGhhRLRRPKTTRSPEVPKSKPALEPATV 573
Cdd:PTZ00449 560 KPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPE-----EPKKPKRPRSAQRPT--RPKSPKLPELLDIPKSPKRPESPKS 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 574 tpeilvPKiVPKPPQKPKATRRPEVPQV----KPAHEP-VTFGseaPALAIVTTTDIEPVITRTKASVTTLAPKpprpRT 648
Cdd:PTZ00449 633 ------PK-RPPPPQRPSSPERPEGPKIikspKPPKSPkPPFD---PKFKEKFYDDYLDAAAKSKETKTTVVLD----ES 698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 649 HRQRTKYKTTQSPKIPHSKPADLGPITSEPPLASTT--KKVRRPRPKPQTTPHPEVPHTILV---PATSLEPFIITEAPG 723
Cdd:PTZ00449 699 FESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEpiGDPDAEQPDDIEFFTPPEEERTFFhetPADTPLPDILAEEFK 778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 724 TTLVPKLPQQPDYPHPKPKttrspaaSPTELVPTPVFE-PVTPLK----------------------EDPVTTIVPITDL 780
Cdd:PTZ00449 779 EEDIHAETGEPDEAMKRPD-------SPSEHEDKPPGDhPSLPKKrhrldglalsttdlesdagriaKDASGKIVKLKRS 851
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 781 ERVTDLET--------PVAFR-------TEAPGT-TLASKISQRTHRPRPRPRPRPRPRPRPKATLSPQAPETKTVPAVV 844
Cdd:PTZ00449 852 KSFDDLTTveeaeemgAEARKivvdddgTEADDEdTHPPEEKHKSEVRRRRPPKKPSKPKKPSKPKKPKKPDSAFIPSII 931
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1447-1527 |
1.10e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 51.08 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1447 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQITNQTFS-TVENLKPDTSYEFQVKPKNPL 1524
Cdd:smart00060 3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1907118362 1525 GEG 1527
Cdd:smart00060 81 GEG 83
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
447-767 |
2.21e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 55.85 E-value: 2.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 447 HTATRDPILDSVP-----PKTSRTAEQPRATLAPIEAlfesrnveiftSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRv 521
Cdd:PTZ00449 567 HKPSKIPTLSKKPefpkdPKHPKDPEEPKKPKRPRSA-----------QRPTRPKSPKLPELLDIPKSPKRPESPKSPK- 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 522 kpAPEPETRPSAQttkaprktkkpghhrlRRPKTTRSPEVPKSKPAlepatvtpeilvpkivPKPPQKPKATRRPEVPQV 601
Cdd:PTZ00449 635 --RPPPPQRPSSP----------------ERPEGPKIIKSPKPPKS----------------PKPPFDPKFKEKFYDDYL 680
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 602 KPAHEPVTFGSEAPALAIVTTTDIEPVITRTKASVTTLAPKPP-RPRThrqrtkykttqsPKIPHSKPADlgpitsePPL 680
Cdd:PTZ00449 681 DAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPkLPRD------------EEFPFEPIGD-------PDA 741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 681 ASTTKKVRRPRPKPQTTPHPEvphtilVPATSLEPFIITEAPGTTLVPKLPQQPDYPHPKPKttrspaaSPTELVPTPVF 760
Cdd:PTZ00449 742 EQPDDIEFFTPPEEERTFFHE------TPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPD-------SPSEHEDKPPG 808
|
....*...
gi 1907118362 761 E-PVTPLK 767
Cdd:PTZ00449 809 DhPSLPKK 816
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1447-1530 |
1.47e-06 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 47.79 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1447 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQITNQTFS-TVENLKPDTSYEFQVKPKNP 1523
Cdd:pfam00041 2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78
|
....*..
gi 1907118362 1524 LGEGPAS 1530
Cdd:pfam00041 79 GGEGPPS 85
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
517-703 |
7.44e-06 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 50.82 E-value: 7.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 517 KPPRVKPAPEPETRPSAQT---TKAPRKTKKPGHHRLRRPKTTRSPEVPkskpaLEPATVTPEILVPKIVPKPPQKPKAT 593
Cdd:PHA03377 414 RKPRTLPWPTPKTHPVKRTlvkTSGRSDEAEQAQSTPERPGPSDQPSVP-----VEPAHLTPVEHTTVILHQPPQSPPTV 488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 594 rrpevpQVKPAHEPVTFGSEApalAIVTTTDIEPVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPK---IPHSKPAD 670
Cdd:PHA03377 489 ------AIKPAPPPSRRRRGA---CVVYDDDIIEVIDVETTEEEESVTQPAKPHRKVQDGFQRSGRRQKratPPKVSPSD 559
|
170 180 190
....*....|....*....|....*....|...
gi 1907118362 671 LGPITSEPPLASTTKKVRRPRPKPQTTPHPEVP 703
Cdd:PHA03377 560 RGPPKASPPVMAPPSTGPRVMATPSTGPRDMAP 592
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1079-1448 |
1.20e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.71 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1079 PPETTIETSPLSSQSIIIPRPDEPQTEPAPRQTT---SMPPKLKTPHS----RMPAKEPVPKEPLHTTSKPKMPPSPEVA 1151
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRArrpDAPPQSARPRApvddRGDPRGPAPPSPLPPDTHAPDPPPPSPS 2632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1152 DTTSVPKDERLSLKPDPEVTHSETAPLETR-----GIPLIPVISPRPSQEELQTAMEETDQSTQELFTTKIPrttelaKT 1226
Cdd:PHA03247 2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP------PP 2706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1227 TQAPHRLHTAPVRPRIPGRPHGRPALNKTTTRPdktKPRGTSHKNGVGTGTKQAPKPPSPGRNASVDSHATRKPGSVSGT 1306
Cdd:PHA03247 2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAP---APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRL 2783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1307 RRPPIPHRHSSTRPVSPERRPLPPNNVTgkPGRAGIVSSSRVTSPPLKATLHPIGTATARPGAEQKEPTAPASEEEFGtt 1386
Cdd:PHA03247 2784 TRPAVASLSESRESLPSPWDPADPPAAV--LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG-- 2859
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907118362 1387 TDFSSSPTKETDPLGKPRFIGPHVRYIPKPENKPCSIT-----DSVRRFPTEEATEGNATSPPQNPP 1448
Cdd:PHA03247 2860 GDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESfalppDQPERPPQPQAPPPPQPQPQPPPP 2926
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1024-1403 |
1.72e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.78 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1024 QSQSVSDDLELVAFSTESPQKTIAPAETDYVDTKEPLRLEEPRTEVVDSLTyvsePPETTIETSPLSSQSIIIPRPDEPQ 1103
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTW----SLSTLAPASPAREGSPTPPGPSSPD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1104 TEPAPRQTTSMPPKLKTPHSRMPAKEPVPKEPLHTTSKPKMPPSPEVADTTSVPKDERLSLKPDPEVTHSETAPLETRGI 1183
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPP 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1184 ----PLIPVISPRPSQEELQTAM----------------EETDQSTQELFTTKIPRTTELAKTTQAPHRLHTAPVRPRIP 1243
Cdd:PHA03307 196 stppAAASPRPPRRSSPISASASspapapgrsaaddagaSSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGW 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1244 GRPHGRPALNKTTTRPDKTKPRGTSHKNGVGTGTKQAPKPPSPGRNASVDSHATRKPGSVS---GTRRPPIPHRH-SSTR 1319
Cdd:PHA03307 276 NGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSrgaAVSPGPSPSRSpSPSR 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1320 PVSPERRPLPPNNVTGKP-GRAGIVSSSRVTSPPLKATLHPIGTATARPGAEQKEPTAPASEEEFGTTTDFSSSPtKETD 1398
Cdd:PHA03307 356 PPPPADPSSPRKRPRPSRaPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY-PLLT 434
|
....*
gi 1907118362 1399 PLGKP 1403
Cdd:PHA03307 435 PSGEP 439
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1079-1404 |
3.91e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1079 PPETTIETSPLSSQSIIIPRPDEPQTEPAPR----QTTSMPPKLKTPH-SRMPAKEPVPKEPLHTTSKPKMPPSpeVADT 1153
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPperpRDDPAPGRVSRPRrARRLGRAAQASSPPQRPRRRAARPT--VGSL 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1154 TSvpkderLSLKPDPEVTHSETAPLETRGIPLIPVISPRPSQEELQTAMEETDQSTQELFTTKIPRTTELAKTTQAPHRL 1233
Cdd:PHA03247 2696 TS------LADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP 2769
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1234 HTAPVRPRIPGRPHGRPA-------LNKTTTRPDKTKPRGTSHKNGVGTGTKQAPKPPSPGRNASVDSHATRKPGSVsgt 1306
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAvaslsesRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--- 2846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1307 rrPPIPHRHSSTRPVSPERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHPIgtatARPGAEQKEPTAPASEEEFGTT 1386
Cdd:PHA03247 2847 --PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESF----ALPPDQPERPPQPQAPPPPQPQ 2920
|
330
....*....|....*...
gi 1907118362 1387 TDFSSSPTKETDPLGKPR 1404
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPR 2938
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1229-1449 |
4.74e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1229 APHRLHTAPVRPRIPGRPHGRP---ALNKTTTRPDKTKPRGTSHKNGVGTGTKQAPKPPSPgrnASVDSHATRKPGSVSG 1305
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPAPRPsepAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSP---LPPDTHAPDPPPPSPS 2632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1306 TRRPPIPHRHSSTRPVSPERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHPIGTATARPGAEQKEPTAPASEEEFGT 1385
Cdd:PHA03247 2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAP 2712
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907118362 1386 TTDFSSSPTKETDPLGKPRFIGPHVRYIPKPENKPCSITDSVRRFPTEEATEG-NATSPPQNPPT 1449
Cdd:PHA03247 2713 HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGpPAPAPPAAPAA 2777
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
384-758 |
1.05e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.07 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 384 PEFPEAKTAFPLEKPRGSWASSEEPWVVPGAKTSEDSRVVQPQTATYDVISSSTTSDETEIEIHTATRDPILDSV----- 458
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPhpplq 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 459 -------PPKTSRTAEQPRATLAPIEALFESrnveIFTSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPE----- 526
Cdd:pfam03154 251 pmtqpppPSQVSPQPLPQPSLHGQMPPMPHS----LQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSqqrih 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 527 -PETRPSAQTTKAPRKTKKP----GHHRLRRPKTTRSPEVPKSKPALEPATVT---PEILVPKIVPKPPQKPKATRRPEV 598
Cdd:pfam03154 327 tPPSQSQLQSQQPPREQPLPpaplSMPHIKPPPTTPIPQLPNPQSHKHPPHLSgpsPFQMNSNLPPPPALKPLSSLSTHH 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 599 PqvkPAHEPVTFGSEAPALAIVTTTDIEPVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEP 678
Cdd:pfam03154 407 P---PSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPT 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 679 PLASTTKKVRRPRPKPQTTPHPeVPHTilvPATSLEPFIITEAPgttlvPKLPQQPDYPHPKPkttRSPAASPTeLVPTP 758
Cdd:pfam03154 484 STSSAMPGIQPPSSASVSSSGP-VPAA---VSCPLPPVQIKEEA-----LDEAEEPESPPPPP---RSPSPEPT-VVNTP 550
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1431-1542 |
1.40e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 46.53 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1431 PTEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQITNQTFSTVENLKP 1510
Cdd:COG3401 220 PSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATVTTTSYTDTGLTN 294
|
90 100 110
....*....|....*....|....*....|...
gi 1907118362 1511 DTSYEFQVKPKNPLG-EGPASNTVAFSTESADP 1542
Cdd:COG3401 295 GTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1431-1585 |
1.96e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 46.15 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1431 PTEEATEGNATSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqitNQTFSTVENL 1508
Cdd:COG3401 314 PSNVVSVTTDLTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGL 387
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907118362 1509 KPDTSYEFQVKPKNPLG-EGPASNTVAFSTESADPRVSEPISAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1585
Cdd:COG3401 388 TPGTTYYYKVTAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
116-195 |
2.26e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 41.63 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPSD-RFYTIRYREKDKEKKWIFQLCPATET--IVENLKPNTVYEF 192
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71
|
...
gi 1907118362 193 GVK 195
Cdd:pfam00041 72 RVQ 74
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
114-195 |
3.05e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.06 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 114 PRKPLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPSDRFYTIRYREKDKEKKWIFQLCPA----TETIVENLKPNTV 189
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTE 69
|
....*.
gi 1907118362 190 YEFGVK 195
Cdd:smart00060 70 YEFRVR 75
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
114-195 |
3.26e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 41.33 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 114 PRKPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpsdrFYTIRYREKDKE--KKWIFQLCPATETIVENLKPNTVYE 191
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYE 71
|
....
gi 1907118362 192 FGVK 195
Cdd:cd00063 72 FRVR 75
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
515-626 |
5.56e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 44.80 E-value: 5.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 515 TPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKttrsPEVPKSKPalePATVTPEILVPKIVPKPPQKPKATR 594
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPK----EPVRETAT---PPPVPPRPVAPPVPHTPESAPKLTR 433
|
90 100 110
....*....|....*....|....*....|..
gi 1907118362 595 RPEVPQVKPAHEPVTFGSEAPALAIVTTTDIE 626
Cdd:PRK14950 434 AAIPVDEKPKYTPPAPPKEEEKALIADGDVLE 465
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
491-703 |
7.28e-04 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 44.37 E-value: 7.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAAPQ---QTTSIPSTPKRQSTPKPPRVKPAPEPETrPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPA 567
Cdd:NF033839 286 EPGNKKPSAPKpgmQPSPQPEKKEVKPEPETPKPEVKPQLEK-PKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPE 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 568 LEPATVTPEilvpKIVPKPPQKPKATRRPEVPQVKPAHEPvtfGSEAPalaivtTTDIEPVITRTKASVTTlAPKPPRPR 647
Cdd:NF033839 365 VKPQPEKPK----PEVKPQPETPKPEVKPQPEKPKPEVKP---QPEKP------KPEVKPQPEKPKPEVKP-QPEKPKPE 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907118362 648 THRQRTKYKTTQSPKIPHSKPAdlgpITSEPPLASTTKKVRRPRPKPQTTPHPEVP 703
Cdd:NF033839 431 VKPQPEKPKPEVKPQPEKPKPE----VKPQPETPKPEVKPQPEKPKPEVKPQPEKP 482
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
553-775 |
1.05e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.76 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 553 PKTTRSPEVPKSKPalePATVTPEILVPKIVPKPPQKPKATRRPEVP-----QVKPAHEPVTFGSEAPALAIVTTTDIEP 627
Cdd:PLN03209 330 PKESDAADGPKPVP---TKPVTPEAPSPPIEEEPPQPKAVVPRPLSPytayeDLKPPTSPIPTPPSSSPASSKSVDAVAK 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 628 VITRTKASVTTLAPKPPRPRTHRQRTKyktTQSPKIPHSKPADLGPITSepplasttkkvrrPRPKPQTTPHPEVPHTIL 707
Cdd:PLN03209 407 PAEPDVVPSPGSASNVPEVEPAQVEAK---KTRPLSPYARYEDLKPPTS-------------PSPTAPTGVSPSVSSTSS 470
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907118362 708 VPATSLEP----FIITEAPGTTLVPKLPQQPDYPHPKPKTTRSPAASPTELVPTPVFEPVTPLKEDPVTTIV 775
Cdd:PLN03209 471 VPAVPDTApataATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALA 542
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
491-705 |
1.29e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.52 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAapQQTTSIPSTPKRqSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGH----HRLRRPKTTRSPEV---PK 563
Cdd:PHA03378 576 PLTSPTTS--QLASSAPSYAQT-PWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRpipmRPLRMQPITFNVLVfptPH 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 564 SKPALEPATVTPEILVPKIVP-----------KPPQKPKATRRPEVPQVKPAHEPVTFGSEAPALAIVTTTDIEPVITRT 632
Cdd:PHA03378 653 QPPQVEITPYKPTWTQIGHIPyqpsptgantmLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPG 732
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907118362 633 KASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHT 705
Cdd:PHA03378 733 RARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPT 805
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
458-771 |
1.89e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.91 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 458 VPPKTSRTAEQPRATLAP---IEALFESRNVEIFTSPEVRPTTAAPQQTTsIPSTPKRQSTPKP-------PRVKPAPEP 527
Cdd:PRK07003 372 VPARVAGAVPAPGARAAAavgASAVPAVTAVTGAAGAALAPKAAAAAAAT-RAEAPPAAPAPPAtadrgddAADGDAPVP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 528 ---ETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPALEPATVTPEILVPKIVPKPPQ--------KPKATRRP 596
Cdd:PRK07003 451 akaNARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAaasredapAAAAPPAP 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 597 EVPQVKPA--HEPVTFGSEAPALAIVTTTDIEPVITRTK--------ASVTTLAPKPPRPRTHRQrtkyktTQSPKIPHS 666
Cdd:PRK07003 531 EARPPTPAaaAPAARAGGAAAALDVLRNAGMRVSSDRGAraaaaakpAAAPAAAPKPAAPRVAVQ------VPTPRARAA 604
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 667 KPADLGPITSEPPLASTTkkvRRPRPkpqttPHPEVPHTILVPATSLEPFIiteAPGTTLVPKLPQQPDYPHPKPKTTRS 746
Cdd:PRK07003 605 TGDAPPNGAARAEQAAES---RGAPP-----PWEDIPPDDYVPLSADEGFG---GPDDGFVPVFDSGPDDVRVAPKPADA 673
|
330 340
....*....|....*....|....*
gi 1907118362 747 PAAsPTELVPTPvfePVTPLkeDPV 771
Cdd:PRK07003 674 PAP-PVDTRPLP---PAIPL--DAI 692
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
420-747 |
1.93e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.15 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 420 SRVVQPQTATYDVISSSTTSDE---------TEIEIHTATRDPILDSVPPKTSRTA-EQPRATLAPIEALFESRNVeIFT 489
Cdd:PRK10263 297 NRATQPEYDEYDPLLNGAPITEpvavaaaatTATQSWAAPVEPVTQTPPVASVDVPpAQPTVAWQPVPGPQTGEPV-IAP 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 490 SPEVRPTTAAPQQTTSIPSTPKRQSTP--KPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPA 567
Cdd:PRK10263 376 APEGYPQQSQYAQPAVQYNEPLQQPVQpqQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQST 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 568 LEP-ATVTPEILVPKIVPKPP---------QKPKATRRPEVPQVKPAHEPVTFGSEapalaivtttdIEPVITRTKASVT 637
Cdd:PRK10263 456 FAPqSTYQTEQTYQQPAAQEPlyqqpqpveQQPVVEPEPVVEETKPARPPLYYFEE-----------VEEKRAREREQLA 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 638 TLAPKPPRPrthrqrTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRrprpkpQTTPHPEVPHTILVPATSLepfi 717
Cdd:PRK10263 525 AWYQPIPEP------VKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVK------KATLATGAAATVAAPVFSL---- 588
|
330 340 350
....*....|....*....|....*....|
gi 1907118362 718 iteAPGTTLVPKLPQQPDYPHPKPKTTRSP 747
Cdd:PRK10263 589 ---ANSGGPRPQVKEGIGPQLPRPKRIRVP 615
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
490-618 |
2.16e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 490 SPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEV-PKSKPAL 568
Cdd:PRK07994 370 VPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSePAAASRA 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907118362 569 EPATVTPEIL-----VPKIVPKPPQKPKATR-RPEVPQVKPAHEPVTFGSEAPALA 618
Cdd:PRK07994 450 RPVNSALERLasvrpAPSALEKAPAKKEAYRwKATNPVEVKKEPVATPKALKKALE 505
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
480-628 |
2.53e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 42.49 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 480 FESRNVEIFTSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPghhrLRRPKTTRSP 559
Cdd:PRK14950 351 LELAVIEALLVPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRP----VAPPVPHTPE 426
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907118362 560 EVPKSKPALEPATVTPEILVPkivPKPPQKPKATRRPEV--PQVKPAHEPVT--FGSEAPALAIVTTTDIEPV 628
Cdd:PRK14950 427 SAPKLTRAAIPVDEKPKYTPP---APPKEEEKALIADGDvlEQLEAIWKQILrdVPPRSPAVQALLSSGVRPV 496
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
515-718 |
3.00e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 42.12 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 515 TPKPPRVKPAPEPETRPSAQTTKAPRKTKKP----GHHRL--RRPKTTRSPEVPKSKPALEPATVTPE--ILVPKIVPKP 586
Cdd:PRK14086 87 TVDPSAGEPAPPPPHARRTSEPELPRPGRRPyegyGGPRAddRPPGLPRQDQLPTARPAYPAYQQRPEpgAWPRAADDYG 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 587 PQKPKATRRPEVPQVKPAHEPVTFGSEAPALAivtttDIEPVITRTKASVTTLAPKPPRPRTHRQRTKYKTTQSPKIPHS 666
Cdd:PRK14086 167 WQQQRLGFPPRAPYASPASYAPEQERDREPYD-----AGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPPPGAGHVHRG 241
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1907118362 667 KPADLGPItSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSLEPFII 718
Cdd:PRK14086 242 GPGPPERD-DAPVVPIRPSAPGPLAAQPAPAPGPGEPTARLNPKYTFDTFVI 292
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
491-766 |
3.05e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.45 E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPALEP 570
Cdd:pfam03154 172 PVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQP 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 571 ATVT--PEILVPKIVPKPPQKPKATRRPEVPQVKPAHEPvtfgseapalaivtttdiepvitrtkasvttlAPKPPRPRT 648
Cdd:pfam03154 252 MTQPppPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQ--------------------------------HPVPPQPFP 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 649 hrqrTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRRPRPkPQTTPHPEVPhtilVPATSLEPfiiteaPGTTLVP 728
Cdd:pfam03154 300 ----LTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQP-PREQPLPPAP----LSMPHIKP------PPTTPIP 364
|
250 260 270
....*....|....*....|....*....|....*...
gi 1907118362 729 KLPQQPDYPHPKPKTTRSPAASPTELVPTPVFEPVTPL 766
Cdd:pfam03154 365 QLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSL 402
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
491-779 |
3.43e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 42.29 E-value: 3.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPALEP 570
Cdd:PHA03369 362 AAAKVAVIAAPQTHTGPADRQRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSPYNPQSPGTSYGPEPVGPVPPQPT 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 571 ATVTPEILVPKIVPKPPQKPKATRRPEVPQVKPAHEPVTFGSEAPalaivtTTDIEPVITRTKASVTTLAPKPPRPRTHR 650
Cdd:PHA03369 442 NPYVMPISMANMVYPGHPQEHGHERKRKRGGELKEELIETLKLVK------KLKEEQESLAKELEATAHKSEIKKIAESE 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 651 QRTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRRPRPKPQTTPHPEVPHTILVPATSLEPFIITEAPGT------ 724
Cdd:PHA03369 516 FKNAGAKTAAANIEPNCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTSTTLAAAAGQGSDTaealag 595
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907118362 725 ---TLVPKLPQQPDYPHpkpktTRSPAASPTELVPTPVFEPVTPLKEDPVTTIVPITD 779
Cdd:PHA03369 596 aieTLLTQASAQPAGLS-----LPAPAVPVNASTPASTPPPLAPQEPPQPGTSAPSLE 648
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
950-1322 |
3.47e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 42.21 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 950 VPATVVLATALTPVTLRTKAPKTTTLAPNVQRTRRPHPrpktTASTGVSESKSAPTELQSlvlKPVTSPSleiIQSQSVS 1029
Cdd:pfam05109 405 ITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAP----NTTTGLPSSTHVPTNLTA---PASTGPT---VSTADVT 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1030 DDLELVAFSTESPQkTIAPAETDYVDTKEPLRLEEPRTEVVDSLTYVSEP-PETTIETSPLSSQSIIIPRPDEPQTEPAP 1108
Cdd:pfam05109 475 SPTPAGTTSGASPV-TPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPtPAVTTPTPNATSPTLGKTSPTSAVTTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1109 RQTTSMPP-KLKTPHSRMPAKEPVPKEPLHTTSKPKmPPSPEVADTTSVPKDERLSL----------KPDPEVTHSETAP 1177
Cdd:pfam05109 554 NATSPTPAvTTPTPNATIPTLGKTSPTSAVTTPTPN-ATSPTVGETSPQANTTNHTLggtsstpvvtSPPKNATSAVTTG 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1178 LETRGIPLIPVISPRPS--QEELQTAMEETDQSTQELFTTKIP----RTTELAKTTQAPHRLHTAPVRPRiPGRPH--GR 1249
Cdd:pfam05109 633 QHNITSSSTSSMSLRPSsiSETLSPSTSDNSTSHMPLLTSAHPtggeNITQVTPASTSTHHVSTSSPAPR-PGTTSqaSG 711
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907118362 1250 PALNKTTTRPDKTK-PRGTSHKNGVgtgtkqAPKPPSPGRNASVDSHAT-RKPGSVSGTRRPPIPHRHSSTRPVS 1322
Cdd:pfam05109 712 PGNSSTSTKPGEVNvTKGTPPKNAT------SPQAPSGQKTAVPTVTSTgGKANSTTGGKHTTGHGARTSTEPTT 780
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
1077-1449 |
3.74e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.06 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1077 SEPPETTIETSPLSSQSIIIPRPDEPQTEPAPRQTTSMPPKLKTPHSRMPAKEPVPKEPLH------TTSKPKMP-PSPE 1149
Cdd:pfam03154 169 TQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTliqqtpTLHPQRLPsPHPP 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1150 VADTTSVPKDERLSLKPDPEVTHSETAPLETRGIPLIPVISPRPSQEELQTAMEETDQSTQELF-TTKIPRTTELAKTTQ 1228
Cdd:pfam03154 249 LQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGpSPAAPGQSQQRIHTP 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1229 APHRLHTAPVRPR---IPGRPHGRPALNKTTTRPDKTKPRGTSHKNgvgtgTKQAPKPPSPGRNASVDSHATRKPGSVSG 1305
Cdd:pfam03154 329 PSQSQLQSQQPPReqpLPPAPLSMPHIKPPPTTPIPQLPNPQSHKH-----PPHLSGPSPFQMNSNLPPPPALKPLSSLS 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1306 TRRPpiPHRHSSTRPVSPERRPLPPnnvtgKPGRAGIVSSSRVTSPPlkATLHPigtataRPGAEQKEPTAPAseeeFGT 1385
Cdd:pfam03154 404 THHP--PSAHPPPLQLMPQSQQLPP-----PPAQPPVLTQSQSLPPP--AASHP------PTSGLHQVPSQSP----FPQ 464
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907118362 1386 TTDFSSSPTKETDPLGKPRFIGPHVRYIPKPENKPCSITDSV-------------RRFPTEEATEGNATSPPQNPPT 1449
Cdd:pfam03154 465 HPFVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGPVpaavscplppvqiKEEALDEAEEPESPPPPPRSPS 541
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
469-600 |
4.12e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 4.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 469 PRATLAPIEALfESRNVEIFTSPEVRPT----TAAPQQTTSIPSTPKRQSTPKPPRVkPAPEPETRPSAQTTKAPRKTKK 544
Cdd:PRK07764 371 ERGLLARLERL-ERRLGVAGGAGAPAAAapsaAAAAPAAAPAPAAAAPAAAAAPAPA-AAPQPAPAPAPAPAPPSPAGNA 448
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907118362 545 PGHHRLRRPKTTRSPEVPKSKPALEPATVTPEILVPKIVPKPPQKPKATRRPEVPQ 600
Cdd:PRK07764 449 PAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPA 504
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
515-612 |
4.82e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 41.47 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 515 TPKPPRVKPAPEPETrPSAQTTKAPRKTKKPGhhrlRRPKTTRSPEvpkSKPAlePATVTPeilVPKIVPKPPqKPKATR 594
Cdd:PRK14954 385 AGSPDVKKKAPEPDL-PQPDRHPGPAKPEAPG----ARPAELPSPA---SAPT--PEQQPP---VARSAPLPP-SPQASA 450
|
90
....*....|....*...
gi 1907118362 595 RPEVPQVKPAhepVTFGS 612
Cdd:PRK14954 451 PRNVASGKPG---VDLGS 465
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
531-802 |
5.56e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 531 PSAQTTKAPRKTKKPGHHRlrrpKTTRSPEVPKSKPALEPATVTPEILVPKIVPKPPQKPKATRRPEVPqvkPAHEPVTF 610
Cdd:PHA03247 255 PAPPPVVGEGADRAPETAR----GATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPPA---PAGDAEEE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 611 GSEAPALAIVTttdiePVitrtkasvttlapkpPRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEPPLASTTKKVRRp 690
Cdd:PHA03247 328 DDEDGAMEVVS-----PL---------------PRPRQHYPLGFPKRRRPTWTPPSSLEDLSAGRHHPKRASLPTRKRR- 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 691 rpkpqTTPHPEVPHTiLVPATSLEPFIITEAPGTTLVPKLPQQPDYPHPKPKTTRSPAASPTELVPTPVFEPVTPLKEDP 770
Cdd:PHA03247 387 -----SARHAATPFA-RGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATE 460
|
250 260 270
....*....|....*....|....*....|...
gi 1907118362 771 VTTivPITDLERVTDLETPVAFRT-EAPGTTLA 802
Cdd:PHA03247 461 PAP--DDPDDATRKALDALRERRPpEPPGADLA 491
|
|
| Not5 |
COG5665 |
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]; |
428-770 |
6.09e-03 |
|
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription];
Pssm-ID: 444384 [Multi-domain] Cd Length: 874 Bit Score: 41.57 E-value: 6.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 428 ATYDVISSSTTSDETEIEIHTATR-------DPILDSVPPKTSRTAEQPRATLAPIEALFESRNVEIFTSPEVR------ 494
Cdd:COG5665 208 STPQAFNASATSGRSQHIVQAAKRvgvewwgDPSLLATPPATPATEEKSSQQPKSQPTSPSGGTTPPSTNQLTTsntpts 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 495 --------PTTAAPQQTTSIPSTPKRQSTPKPPRV--KPAPEPETRPSAQTTKAPRKTKKPGHhrlrRPKTTRSPEVPKS 564
Cdd:COG5665 288 takaqpqpPTKKQPAKEPPSDTASGNPSAPSVLINsdSPTSEDPATASVPTTEETTAFTTPSS----VPSTPAEKDTPAT 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 565 KPALEPATVTPEILV-PKIVPKPPQKPKATrrpevpqvkpAHEPVTFGSEAPalaivtttdiepvitrtkASVTTLAPKP 643
Cdd:COG5665 364 DLATPVSPTPPETSVdKKVSPDSATSSTKS----------EKEGGTASSPMP------------------PNIAIGAKDD 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 644 PRPRTHRQRTKYKTTQSPKIPHSKPADLGPITSEPPLAS--------TTKKVRRPRPKPQTTPHPEVPHTILVPATSLEP 715
Cdd:COG5665 416 VDATDPSQEAKEYTKNAPMTPEADSAPESSVRTEASPSAgsdlepenTTLRDPAPNAIPPPEDPSTIGRLSSGDKLANET 495
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 716 FIITEAPGTTLVPKLPQQ--PDYPHPKPKTT---RSPAASPTELVPTPVFEPVTPLKEDP 770
Cdd:COG5665 496 GPPVIRRDSTPSSTADQSivGVLAFGLDQRTqaeISVEAASRSNPLLNSQVKSFPLGKRS 555
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
491-673 |
6.11e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.40 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 491 PEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKAPRKTKKPGHHRLRRPKTTRSPEVPKSKPALEP 570
Cdd:PRK12323 383 AQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAA 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 571 ATVTPEIL---VPKIVPKPPQKPKATRRPEVPQVKPAHE-PVTFGSEAPA------LAIVTTTDIEPVITRTKASVTTLA 640
Cdd:PRK12323 463 RPAAAGPRpvaAAAAAAPARAAPAAAPAPADDDPPPWEElPPEFASPAPAqpdaapAGWVAESIPDPATADPDDAFETLA 542
|
170 180 190
....*....|....*....|....*....|...
gi 1907118362 641 PKPPRPRTHRQRTKYKTTQSPKIPHSKPADLGP 673
Cdd:PRK12323 543 PAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1443-1542 |
6.64e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 40.91 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907118362 1443 PPQNPpTNLTVVTVEgcPSFVILDWEK-PLNDTVTEYEVisrengsFSGKNKSIQITNQTFSTVENLKPDTSYEFQVKPK 1521
Cdd:COG3979 2 APTAP-TGLTASNVT--SSSVSLSWDAsTDNVGVTGYDV-------YRGGDQVATVTGLTAWTVTGLTPGTEYTFTVGAC 71
|
90 100
....*....|....*....|.
gi 1907118362 1522 nplgeGPASNTVAFSTESADP 1542
Cdd:COG3979 72 -----DAAGNVSAASGTSTAM 87
|
|
| |
