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Conserved domains on  [gi|1907088898|ref|XP_036013489|]
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RNA-binding protein 25 isoform X5 [Mus musculus]

Protein Classification

PWI domain-containing protein( domain architecture ID 10645659)

PWI domain-containing protein may function as a splicing factor; similar to Saccharomyces cerevisiae U1 small nuclear ribonucleoprotein component SNU71, a component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PWI smart00311
PWI, domain in splicing factors;
554-627 1.12e-25

PWI, domain in splicing factors;


:

Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 100.50  E-value: 1.12e-25
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907088898  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74
 
Name Accession Description Interval E-value
PWI smart00311
PWI, domain in splicing factors;
554-627 1.12e-25

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 100.50  E-value: 1.12e-25
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907088898  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74
PWI pfam01480
PWI domain;
562-629 8.25e-13

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 63.68  E-value: 8.25e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907088898 562 IRPWINKKIIEYIGEEEATLVDFVCSKV-MAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKK 629
Cdd:pfam01480   3 LKPWIEKKITEILGFEDDVVVEYVVNLLeEKFPDPKELQIQLTGFLDKDAAKFVKELWKLLLSAQESPS 71
 
Name Accession Description Interval E-value
PWI smart00311
PWI, domain in splicing factors;
554-627 1.12e-25

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 100.50  E-value: 1.12e-25
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907088898  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74
PWI pfam01480
PWI domain;
562-629 8.25e-13

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 63.68  E-value: 8.25e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907088898 562 IRPWINKKIIEYIGEEEATLVDFVCSKV-MAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKK 629
Cdd:pfam01480   3 LKPWIEKKITEILGFEDDVVVEYVVNLLeEKFPDPKELQIQLTGFLDKDAAKFVKELWKLLLSAQESPS 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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