|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
2.78e-87 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 279.75 E-value: 2.78e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 90 YQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
6.81e-60 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 202.08 E-value: 6.81e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
1.99e-59 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 200.51 E-value: 1.99e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
4.03e-36 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 134.96 E-value: 4.03e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 76 IHNLSILVKQIKFYYQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 1907079586 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
1.11e-20 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 89.64 E-value: 1.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDAS--LRIHNLSILVKQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 94 LQQLIM-MPLPDILIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
258-1079 |
2.58e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 94.74 E-value: 2.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 258 AKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEseLSRYKERLH 337
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLR--LEELREELE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 338 DIEFYKARVEELKEDNQVLLETktmLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Cdd:TIGR02168 243 ELQEELKEAEEELEELTAELQE---LEEKLEELRLEvselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 414 TLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEELRSTADSAAGS---- 489
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL-EAELEELESRLEELEEQLETLRSKVAQLELQiasl 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 490 TSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQ--NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV 567
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 568 SSLRQRSQISAEARV-KDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAEELENELNHLGKENeLLQK 646
Cdd:TIGR02168 479 AAERELAQLQARLDSlERLQENLEGFSEGVKA-------LLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGR-LQAV 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 647 KITNLKITCEKLETLEQENS--------------ELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES 712
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQNELgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 713 LKCASMRMAQLQLENKELESEKEQLRKGlelmRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEME 792
Cdd:TIGR02168 631 LDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 793 NQTLQKSLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Cdd:TIGR02168 707 LEELEEELEQLRKeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 869 LFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Cdd:TIGR02168 787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 949 TDDSryklLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEdd 1028
Cdd:TIGR02168 867 LIEE----LESELEA-LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID-- 939
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 1029 kwgrESQEATREllKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1079
Cdd:TIGR02168 940 ----NLQERLSE--EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
581-1226 |
3.82e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 87.42 E-value: 3.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 581 RVKDIEKENKIlhESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKitnlkitcEKLET 660
Cdd:TIGR02168 171 KERRKETERKL--ERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLE--------ELREE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 661 LEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRM-AQLQLENKELESEKEQLRK 739
Cdd:TIGR02168 241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRERLANLERQLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 740 GLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKS 819
Cdd:TIGR02168 321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 820 LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATI 899
Cdd:TIGR02168 398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD-----EQSTDDSRYKL-----LESKLESTLKKSL 969
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAaieaaLGGRLQAVVVENL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 970 EIKEEKIAALE-------ARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIP-------------------- 1022
Cdd:TIGR02168 556 NAAKKAIAFLKqnelgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddldnal 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1023 -------------------------VSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN 1077
Cdd:TIGR02168 636 elakklrpgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1078 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALI 1157
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 1158 KDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:TIGR02168 796 EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
250-875 |
1.90e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.11 E-value: 1.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 250 SVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSARMYRDEL-----DALREKAVRVDK 324
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----LEELRLEVSELEEEieelqKELYALANEISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 325 LESELSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02168 300 LEQQKQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 397 ERDMDRKKIEELmEENMTLEMAQKQSMDESL-HLGWELEQ-ISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTK 474
Cdd:TIGR02168 380 QLETLRSKVAQL-ELQIASLNNEIERLEARLeRLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 475 TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN-------------EIIQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 542 IET-LRENSErqiKILEQENEHLNQTVSSLRQ----RSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE 616
Cdd:TIGR02168 539 IEAaLGGRLQ---AVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 617 -------------------LELYKEKGERAE---------------------------ELENELNHLGKENELLQKKITN 650
Cdd:TIGR02168 616 kalsyllggvlvvddldnaLELAKKLRPGYRivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAE 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 651 LKITCEKLET--------LEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES---------- 712
Cdd:TIGR02168 696 LEKALAELRKeleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEleerleeaee 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 713 -LKCASMRMAQLQLENKELESEKEQLRKGL--------ELMRASFKKTERLEVSYQGLD---TENQRLQKALENSNKKIQ 780
Cdd:TIGR02168 776 eLAEAEAEIEELEAQIEQLKEELKALREALdelraeltLLNEEAANLRERLESLERRIAateRRLEDLEEQIEELSEDIE 855
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 781 QLESELQDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:TIGR02168 856 SLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932
|
730
....*....|....*
gi 1907079586 861 NLEKENKTLFKEINV 875
Cdd:TIGR02168 933 GLEVRIDNLQERLSE 947
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
4.62e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 76.52 E-value: 4.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKSESQ----RVNKKVNNDASLRIHNLSILVKQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 91 QETL-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-1213 |
4.78e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.95 E-value: 4.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 529 KDLMKEKAQLEKTI---ETLRENSERQIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKET 599
Cdd:TIGR02168 235 EELREELEELQEELkeaEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkelyALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 600 CGKLSKIEFEKRQMKKELELYKEkgeRAEELENELNHLGKENELLQKKITNLKITCEKLETLEQE-NSELERENRKFKKT 678
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 679 LDSFKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSY 758
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEEL-----LKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL-----------EKENKSLE---QET 824
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdEGYEAAIEaalGGR 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 825 SQ--LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEnkelVKRATIDIK 902
Cdd:TIGR02168 547 LQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLL 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 903 TLVTLREDLvseklktQQMNNDLEKLTHELEKIGLNKERLlhdeqSTDDSRYKLLESKLESTLKKSLEIKE--EKIAALE 980
Cdd:TIGR02168 623 GGVLVVDDL-------DNALELAKKLRPGYRIVTLDGDLV-----RPGGVITGGSAKTNSSILERRREIEEleEKIEELE 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 981 ARLEESTNYNQQLRHELKTVKKNYEALKQRQDE-------------------ERMVQSSIPVSGEDDKWGRESQEATREL 1041
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEElsrqisalrkdlarleaevEQLEERIAQLSKELTELEAEIEELEERL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1042 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1121
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1122 mnqNAQLLIQQSSLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:TIGR02168 851 ---SEDIESLAAEIEELEELIEELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923
|
730
....*....|..
gi 1907079586 1202 YNQLLKQKGQLE 1213
Cdd:TIGR02168 924 LAQLELRLEGLE 935
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1224 |
7.60e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.19 E-value: 7.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 610 KRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 690 ESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 770 KALENSNKKiqqlESELQDLEMENQTLQKSLEELKISSKRLE---QLEKENKSLEQETSQLEKDKkqLEKENKRLRQQAE 846
Cdd:PRK03918 328 ERIKELEEK----EERLEELKKKLKELEKRLEELEERHELYEeakAKKEELERLKKRLTGLTPEK--LEKELEELEKAKE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 847 IKDTTLEENNVKIGNLEKENKTLFKEINVYKES------CVRLKElEKENKELVKRATIDIKtlvtlreDLVSEKLKTQQ 920
Cdd:PRK03918 402 EIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvCGRELT-EEHRKELLEEYTAELK-------RIEKELKEIEE 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 921 MNNDLEKLTHELEKIGLNKERLLHDEQSTDdsRYKLLESKLESTLKKSLEIKEEKIAALEARLEEstnynqqLRHELKTV 1000
Cdd:PRK03918 474 KERKLRKELRELEKVLKKESELIKLKELAE--QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK-------LKGEIKSL 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1001 KKNYEALKQRQDEERMVQSSIpvsgeddkwgresQEATRELLKVKDRLIEVERNNAtlqaekQALKTQLKQLEtqnnnlq 1080
Cdd:PRK03918 545 KKELEKLEELKKKLAELEKKL-------------DELEEELAELLKELEELGFESV------EELEERLKELE------- 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1081 aqilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESIMKEREDLKSLYDAliKDH 1160
Cdd:PRK03918 599 ----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKYSE--EEY 661
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 1161 EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQE 1224
Cdd:PRK03918 662 EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
605-1220 |
1.42e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 605 KIEFEKRQMKKELEL--YKEKGERAEELENELNHLGKENELLQKKITNLKitceklETLEQENSELERENRKFKKTLDSF 682
Cdd:COG1196 217 ELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEAELAELE------AELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 683 KNLTFQLESLEKENSQLDEENLELRRsveslkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKK-TERLEVSYQGL 761
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEE----------RLEELEEELAELEEELEELEEELEELEEELEEaEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 762 DTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 842 RQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQm 921
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG- 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 922 NNDLEKLTHELEKIGLNKE---------RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQ 992
Cdd:COG1196 519 LRGLAGAVAVLIGVEAAYEaaleaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 993 LRHELKTVKKNYEALKQRQDEERMVQSSIpvsgEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1072
Cdd:COG1196 599 AAVDLVASDLREADARYYVLGDTLLGRTL----VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1073 ETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSL 1152
Cdd:COG1196 675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 1153 YDALIKDHEKLellhERQASEYESLISKHGTLksahkNL--EVEHKDLEDRYNQLLKQKGQLE----DLEKMIK 1220
Cdd:COG1196 755 ELPEPPDLEEL----ERELERLEREIEALGPV-----NLlaIEEYEELEERYDFLSEQREDLEeareTLEEAIE 819
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
3.31e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 81.27 E-value: 3.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD----------------ARSARMYRDELDAL 315
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrvkekigeleaeiASLERSIAEKEREL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 316 REKAVRVDKLESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMe 395
Cdd:TIGR02169 318 EDAEERLAKLEAEIDKLLAEIEELE---REIEEERKRRDKLTEEYAELKEELEDLRAE---LEEVDKEFAETRDELKDY- 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 396 merdmdRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKslghEVNELTSSKLLKLEMENQSLTKT 475
Cdd:TIGR02169 391 ------REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN----ELEEEKEDKALEIKKQEWKLEQL 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 476 VEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENE--IIQEKQ------------SLQNCQNLSKDLMKEKAQLEKT 541
Cdd:TIGR02169 461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQarASEERVrggraveevlkaSIQGVHGTVAQLGSVGERYATA 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 542 IETLREN------------SERQIKILEQENEH------LNQTVSSLRQRSQISAEAR---------------------- 581
Cdd:TIGR02169 541 IEVAAGNrlnnvvveddavAKEAIELLKRRKAGratflpLNKMRDERRDLSILSEDGVigfavdlvefdpkyepafkyvf 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 582 -----VKDIEK-------------ENKILHESIKETCGKLSKIEFEKRQmKKELELYKEKGERAEELENELNHLGKENEL 643
Cdd:TIGR02169 621 gdtlvVEDIEAarrlmgkyrmvtlEGELFEKSGAMTGGSRAPRGGILFS-RSEPAELQRLRERLEGLKRELSSLQSELRR 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 644 LQKKITNLKITCE----KLETLEQENSELERENRKFKKTLDSFK-----------NLTFQLESLEKENSQLDEENLELRR 708
Cdd:TIGR02169 700 IENRLDELSQELSdasrKIGEIEKEIEQLEQEEEKLKERLEELEedlssleqeieNVKSELKELEARIEELEEDLHKLEE 779
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 709 SVESLKcASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQD 788
Cdd:TIGR02169 780 ALNDLE-ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 789 LEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Cdd:TIGR02169 859 LNGKKEELEEELEELE---AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
|
730 740 750
....*....|....*....|....*....|....*.
gi 1907079586 869 LFKEINVYKESCVRLKELEKENKELvKRATIDIKTL 904
Cdd:TIGR02169 936 IEDPKGEDEEIPEEELSLEDVQAEL-QRVEEEIRAL 970
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1108 |
3.99e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 80.93 E-value: 3.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQSmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIRR-- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 425 eslhlgweleqisRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKtVEELRSTADSAAGSTSKILKVEKENQRLN 504
Cdd:pfam15921 135 -------------RESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 505 KKvEILENEIIQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIKIL-EQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIELLlQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETCG----KLSKIEFEKRQMKKELELYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 635 NHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRSVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLlADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 714 KC--------ASMRMAQLQLENK----------ELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 776 NKKIQQLES-------ELQDLEMEN---QTLQKSLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLfkeINVYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 908 REDLVSEKL----KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLesKLESTLKKSLEIKEEKIAALEAR- 982
Cdd:pfam15921 673 SEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM--KVAMGMQKQITAKRGQIDALQSKi 750
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 983 --LEESTNYNQQLRHELKtvkknyealkqrQDEERMVQSSIPVSGEDDKWGREsqeatRELLKVKDRLIEVERNNATLQA 1060
Cdd:pfam15921 751 qfLEEAMTNANKEKHFLK------------EEKNKLSQELSTVATEKNKMAGE-----LEVLRSQERRLKEKVANMEVAL 813
|
810 820 830 840
....*....|....*....|....*....|....*....|....*...
gi 1907079586 1061 EKQALKTQLKQLETQNNNLQAQILALQrQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:pfam15921 814 DKASLQFAECQDIIQRQEQESVRLKLQ-HTLDVKELQGPGYTSNSSMK 860
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
578-1073 |
1.00e-14 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 79.34 E-value: 1.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 578 AEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEK 657
Cdd:PRK03918 198 KEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 658 LETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQL 737
Cdd:PRK03918 278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 738 RKGLELMRASFKKTERLE--------VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKiSSKR 809
Cdd:PRK03918 358 EERHELYEEAKAKKEELErlkkrltgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKG 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLrQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE 889
Cdd:PRK03918 437 KCPVCGRELTEEHRKELLEEYTAELKRIEKEL-KEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKY 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 890 NKELVKRATIDIKTL----VTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE 962
Cdd:PRK03918 516 NLEELEKKAEEYEKLkeklIKLKGEiksLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLK 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 963 S------------TLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQssipVSGEDDKW 1030
Cdd:PRK03918 596 ElepfyneylelkDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLEL 671
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 1907079586 1031 GRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:PRK03918 672 SRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
505-1209 |
1.01e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.73 E-value: 1.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 505 KKVEILENEIIQEKQSLQNCQNLS---KDLMKEKAQLE--------KTIETLRENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR02169 187 ERLDLIIDEKRQQLERLRREREKAeryQALLKEKREYEgyellkekEALERQKEAIERQLASLEEELEKLTEEISELEKR 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 574 SQiSAEARVKDIEKE-NKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEE----LENELNHLGKENELLQKKI 648
Cdd:TIGR02169 267 LE-EIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEErlakLEAEIDKLLAEIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 649 TNLKITCEKL--------ETLEQENSELERENRKFKKTLDSFKNLTfqlESLEKENSQLDEENLELRRSVESLKCASMRM 720
Cdd:TIGR02169 346 EEERKRRDKLteeyaelkEELEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEEL 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 721 AQLQLENKELESEKEQLRKGLELMRASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSL 800
Cdd:TIGR02169 423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 801 EELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQ----LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:TIGR02169 493 AEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERyataIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKA 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 866 NKTLFKEINVYKES---------------CVRLKELEKENKELVK---------------RATIDIKTLVTLREDLV--- 912
Cdd:TIGR02169 573 GRATFLPLNKMRDErrdlsilsedgvigfAVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMVTLEGELFeks 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 913 ------------------SEKLKTQQMNNDLEKLTHELEKIGLNKERL---------------------------LHDEQ 947
Cdd:TIGR02169 653 gamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSLQSELRRIenrldelsqelsdasrkigeiekeieqLEQEE 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 948 STDDSRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVK--------KNYEALKQRQDEERMVQS 1019
Cdd:TIGR02169 733 EKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarlshsriPEIQAELSKLEEEVSRIE 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1020 SI--PVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1097
Cdd:TIGR02169 812 ARlrEIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1098 TTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKER-------------EDLKSLYDALIKDHEKLE 1164
Cdd:TIGR02169 892 DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKgedeeipeeelslEDVQAELQRVEEEIRALE 971
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 1907079586 1165 LLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQK 1209
Cdd:TIGR02169 972 PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1015 |
2.55e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 2.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 701 EENL--------ELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLEL--MRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 851 TLEENNVKIGNLEKEnktlfkeinvYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEE----------LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEE--EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
....*
gi 1907079586 1011 QDEER 1015
Cdd:COG1196 486 LAEAA 490
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
250-1075 |
3.32e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 77.80 E-value: 3.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 250 SVELADAKAKIRRLRQELE------EKTEQLLDCKQELEQIEVELKRLQQENMNllsdaRSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 183 EENIERLDLIIDEKRQQLErlrrerEKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 324 KLESELS-RYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISELEkRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSskllKLEMENQSLTKTV 476
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR----EINELKRELDRLQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 477 EELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIiqeKQSLQNCQNLSKDLMKEKAQLEKTIETLREnSERQIKIL 556
Cdd:TIGR02169 413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI---KKQEWKLEQLAADLSKYEQELYDLKEEYDR-VEKELSKL 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 557 EQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TCGKLSKIEFEKRQMKKE-LELY 620
Cdd:TIGR02169 489 QRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVAKEaIELL 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 621 KE-KGERAEELE-NELNHLGKENELLQKK-----ITNLkITCEKL----------ETLEQENSELEREnrkfkkTLDSFK 683
Cdd:TIGR02169 568 KRrKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDL-VEFDPKyepafkyvfgDTLVVEDIEAARR------LMGKYR 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 684 NLTFQLESLEKENS----------------QLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRkglELMRAS 747
Cdd:TIGR02169 641 MVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS---QELSDA 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 748 FKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE--ELKISSKRLEQLEKENKSLEQETS 825
Cdd:TIGR02169 715 SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEARLSHSRIP 794
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKRatidiktlv 905
Cdd:TIGR02169 795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE---QIKSIEKEIENLNGK--------- 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 906 tlREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddsrYKLLESKLEsTLKKSLEIKEEKIAALEARLEe 985
Cdd:TIGR02169 863 --KEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ------LRELERKIE-ELEAQIEKKRKRLSELKAKLE- 927
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 986 stNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQAL 1065
Cdd:TIGR02169 928 --ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
|
890
....*....|
gi 1907079586 1066 KTQLKQLETQ 1075
Cdd:TIGR02169 1006 LERIEEYEKK 1015
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
4.48e-14 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 77.41 E-value: 4.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 181 MSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHdmEMERDMDRKKIEELMEENMTLEMAQK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLK--ELEKRLEELEERHELYEEAKAKKEEL 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 421 QSMDESLHlGWELEQISRTSELAEAPQKSLGHEVNELTsSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKEN 500
Cdd:PRK03918 375 ERLKKRLT-GLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKE 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 501 QRLNKKVEIleneiiqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQRSQISA 578
Cdd:PRK03918 453 LLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLK 513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 579 EARVKDIEKENKiLHESIKEtcgKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCekL 658
Cdd:PRK03918 514 KYNLEELEKKAE-EYEKLKE---KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFES--V 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 659 ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmrmaqlqlenKELESEKEQLR 738
Cdd:PRK03918 588 EELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL--------------EELRKELEELE 653
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 739 KglelmRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLE 814
Cdd:PRK03918 654 K-----KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVE 724
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
4.71e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 70.90 E-value: 4.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSwfTEAwlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
504-1164 |
1.34e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 75.44 E-value: 1.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 504 NKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIEtlreNSERQIKILEQENEHLN-QTVSSLRQRSQISAEARV 582
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKIN----NSNNKIKILEQQIKDLNdKLKKNKDKINKLNSDLSK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 583 KDIEKENKILHESIKETcgKLSKIEFEKRQMKKELELYKEkgeRAEELENELNHLGKENELLQKKITNLKitcEKLETLE 662
Cdd:TIGR04523 108 INSEIKNDKEQKNKLEV--ELNKLEKQKKENKKNIDKFLT---EIKKKEKELEKLNNKYNDLKKQKEELE---NELNLLE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 663 QENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQLRKgle 742
Cdd:TIGR04523 180 KEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK------DNIEKKQQEINEKTTEISN--- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 743 lmraSFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE---------ELKISSKRLEQL 813
Cdd:TIGR04523 251 ----TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkelksELKNQEKKLEEI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKEL 893
Cdd:TIGR04523 327 QNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKL 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE--SKLESTLKKSLEI 971
Cdd:TIGR04523 407 NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlSRSINKIKQNLEQ 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 972 KEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeermvqssipvsgeddKWGRESQEATRELLKVKDRLIEV 1051
Cdd:TIGR04523 487 KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIE----------------KLESEKKEKESKISDLEDELNKD 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1052 ERNNatlqaekqalktqlkqletQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131
Cdd:TIGR04523 551 DFEL-------------------KKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611
|
650 660 670
....*....|....*....|....*....|...
gi 1907079586 1132 QSSLENENESIMKEREDLKSLYDALIKDHEKLE 1164
Cdd:TIGR04523 612 ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
492-833 |
2.29e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.10 E-value: 2.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 492 KILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVS 568
Cdd:TIGR02169 682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELK 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 569 SLRQRSQISAEARVKDIEKENKI----LHESIKETCGKLSKIEFEKRQMKKelelykekgeRAEELENELNHLGKENELL 644
Cdd:TIGR02169 762 ELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYL 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 645 QKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKENSQLDEENLELRRSVESLKcASMRMAQLQ 724
Cdd:TIGR02169 832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE------ELEELEAALRDLESRLGDLKKERDELE-AQLRELERK 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 725 LENKELESEKEQLRKGLELMRASFKKTERLEV-SYQGLDTENQRLQKALENSNKKIQQLESELQDLEMEN----QTLQKS 799
Cdd:TIGR02169 905 IEELEAQIEKKRKRLSELKAKLEALEEELSEIeDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmlaiQEYEEV 984
|
330 340 350
....*....|....*....|....*....|....
gi 1907079586 800 LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:TIGR02169 985 LKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1252 |
3.51e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 74.62 E-value: 3.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 577 SAEARVKDIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCE 656
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQV----LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 657 KLETLEQENSELERENRKFKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 732 ---SEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQksLEELKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL--LKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKES--CVRLKEL 886
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK 966
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 967 KSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGE--DDKWGRESQEATRELLKV 1044
Cdd:pfam02463 643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKkkEQREKEELKKLKLEAEEL 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:pfam02463 723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1125 NAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:pfam02463 803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 1907079586 1205 LLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRSRY 1252
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE 928
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
465-895 |
6.29e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.52 E-value: 6.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 465 LEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIE 543
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEK 623
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 624 gerAEELENELNHLGKENELLQKKItnlkitceklETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEEN 703
Cdd:TIGR04523 393 ---INDLESKIQNQEKLNQQKDEQI----------KKLQQEKELLEKEIERLKETIIKNNS---EIKDLTNQDSVKELII 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 704 LELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKterLEVSYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:TIGR04523 457 KNLDNTRESLE---TQLKVLSRSINKIKQNLEQKQKELKSKEKELKK---LNEEKKELEEKVKDLTKKISSLKEKIEKLE 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 784 SELQDLEMENQTLQKSLEELKI-------------SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:TIGR04523 531 SEKKEKESKISDLEDELNKDDFelkkenlekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK 610
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1907079586 851 TLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVK 895
Cdd:TIGR04523 611 KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
247-841 |
1.24e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.66 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLE 326
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ------AEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 327 SELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Cdd:COG1196 302 QDIARLEERRRELE---ERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEapqkslghevnELTSSKLLKLEMENQSLTKTVEELRSTADSA 486
Cdd:COG1196 376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL-----------ERLERLEEELEELEEALAELEEEEEEEEEAL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 487 AGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNcQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQT 566
Cdd:COG1196 445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 567 VSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQmkkelelykeKGERAEELENELNHLGKENELLQK 646
Cdd:COG1196 524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA----------KAGRATFLPLDKIRARAALAAALA 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 647 KITNLkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE 726
Cdd:COG1196 594 RGAIG----AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 727 NKELESEKEQLRKGLELMRASFKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKIS 806
Cdd:COG1196 670 LLAALLEAEAELEELAERLAEEELELEEA-----LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744
|
570 580 590
....*....|....*....|....*....|....*
gi 1907079586 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
1.36e-12 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 66.92 E-value: 1.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPayfdENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
257-943 |
1.66e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 1.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESELSRYKERL 336
Cdd:COG1196 171 KERKEEAERKLEATEENLERLEDILGELERQLEPLERQ-------AEKAERYR----ELKEELKELE-AELLLLKLRELE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 337 HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:COG1196 239 AELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 417 MAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAgstsKILKV 496
Cdd:COG1196 316 ERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE----ELEEL 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 577 SAEARVKDIEKENKILHESIKEtcGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQ-KKITNLKITC 655
Cdd:COG1196 465 LAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGvEAAYEAALEA 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 656 EKLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRS------VESLKCASMRMAQLQLEN 727
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVLGDTL 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 728 KELESEKEQLRKGLELMRASfkkTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS 807
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLFKEINVYKEscvRL 883
Cdd:COG1196 700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER---EI 776
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907079586 884 KELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 777 EALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
1.35e-11 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 63.74 E-value: 1.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPswfnEAWLGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 94 L-QQLIMMPLPDILIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
241-829 |
2.16e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.81 E-value: 2.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKA 319
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAElARLEQDIARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 320 VRVDKLESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG1196 316 ERLEELEEELAELEEELEELE---EELEELEEELEEAEEELEEAEAELAEAEEA---LLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 400 MDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEEL 479
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 480 RSTADSAAGSTSKILKVEKENQRLNKKVEileneiIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ- 558
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAa 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 559 -ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETcGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHL 637
Cdd:COG1196 544 lAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR-AALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 638 GKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcaS 717
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL--L 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 718 MRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTL- 796
Cdd:COG1196 701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALg 780
|
570 580 590
....*....|....*....|....*....|....*.
gi 1907079586 797 ---QKSLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:COG1196 781 pvnLLAIEEYEELEERYDFLSEQREDLEEARETLEE 816
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-878 |
2.84e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 68.17 E-value: 2.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 136 QKKEEFIEKIQGLDFDTKAAVAAHIQEVTHNQENVFDLQwmEVTDMSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI--AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 216 EERDGVhflphasssaqspcGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEN 295
Cdd:TIGR02169 350 KRRDKL--------------TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 296 MNLLSDARSARMyrdELDALREKavrVDKLESELsrykerlhdiefyKARVEELKEDNQVLLETKTMLEDQLEGTRARSD 375
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAK---INELEEEK-------------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 376 KLHELEKENLQLKAKLHDMEMERD------MDRKKIEELMEENMT---LEMAQKQSMDESLHLGWELEQISRTSEL---- 442
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKASIQgvhGTVAQLGSVGERYATAIEVAAGNRLNNVvved 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 443 ----AEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVE---------------ELRSTADSAAGSTSKILKVEkENQRL 503
Cdd:TIGR02169 557 davaKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdlvefdpKYEPAFKYVFGDTLVVEDIE-AARRL 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 504 NKKVEI--LENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS---ERQIKILEQENEHLNQTVSSLRQRSQiSA 578
Cdd:TIGR02169 636 MGKYRMvtLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLeglKRELSSLQSELRRIENRLDELSQELS-DA 714
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 579 EARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKITNLK--ITCE 656
Cdd:TIGR02169 715 SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE---LKELEARIEELEEDLHKLEEALNDLEarLSHS 791
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 657 KLETLEQENSELERENRKFKKTLDS----FKNLTFQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELES 732
Cdd:TIGR02169 792 RIPEIQAELSKLEEEVSRIEARLREieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE---KEIENLNGKKEELEE 868
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 733 EKEQLRKGLelmrasfkktERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQ 812
Cdd:TIGR02169 869 ELEELEAAL----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIED 938
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 813 LEKENKSLEQETSQLEKDKKQLEKENKRLR----------QQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKE 878
Cdd:TIGR02169 939 PKGEDEEIPEEELSLEDVQAELQRVEEEIRalepvnmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-888 |
3.13e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 68.17 E-value: 3.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 325 LESELSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELAEAPQKSLGHEVNELTSS--KLLKLEMENQSLTKTVEELR 480
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIRELEERieELKKEIEELEEKVKELKELK 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 481 STADSAAGSTSKILKVEKENQRLNKKVEILENEI--IQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Cdd:PRK03918 290 EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIngIEERiKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 558 QENEhLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYK---------------- 621
Cdd:PRK03918 370 KKEE-LERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgreltee 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELerenRKFKKTLDSFKNL-----TFQLESLEKEN 696
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL----IKLKELAEQLKELeeklkKYNLEELEKKA 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 697 SQ---LDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGL-----ELMRASFKKTERLEVSYQGLDTENQRL 768
Cdd:PRK03918 525 EEyekLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaellkELEELGFESVEELEERLKELEPFYNEY 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 769 QKaLENSNKKIQQLESELQDLEMEnqtLQKSLEELKISSKRLEQLEKENKSLEQETSqlEKDKKQLEKENKRLRQQAEIK 848
Cdd:PRK03918 605 LE-LKDAEKELEREEKELKKLEEE---LDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGL 678
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1907079586 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEK 888
Cdd:PRK03918 679 RAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-934 |
3.46e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 68.17 E-value: 3.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLgKENELLQKKITNLKitceKLETLEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY-EGYELLKEKEALER----QKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 674 KfkktldsfknLTFQLESLEKENSQLDEENLELRRSVESLkcASMRMAQLQLENKELESEKEQLRKGLElmrASFKKTER 753
Cdd:TIGR02169 255 K----------LTEEISELEKRLEEIEQLLEELNKKIKDL--GEEEQLRVKEKIGELEAEIASLERSIA---EKERELED 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 754 LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:TIGR02169 320 AEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR---AELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKEnkelVKRATIDIKTLVTLREDLVS 913
Cdd:TIGR02169 397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE---EKEDKALE----IKKQEWKLEQLAADLSKYEQ 469
|
330 340
....*....|....*....|.
gi 1907079586 914 EKLKTQQMNNDLEKLTHELEK 934
Cdd:TIGR02169 470 ELYDLKEEYDRVEKELSKLQR 490
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1148 |
1.07e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.70 E-value: 1.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 413 MTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKlEMENQSLTKTVEELRSTADSAAGSTSK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 493 ILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 570 LRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGE---RAEELENELNHLGKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 647 KITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCAS--------- 717
Cdd:PTZ00121 1337 KAE------EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEedkkkadel 1410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 718 MRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQtLQ 797
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AK 1489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 798 KSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKdttlEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:PTZ00121 1490 KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEELKKAEEKKK 1565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 878 escVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLL 957
Cdd:PTZ00121 1566 ---AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 958 --ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQ 1035
Cdd:PTZ00121 1643 aeEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1036 EATREllkvkdRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:PTZ00121 1723 KAEEE------NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV 1796
|
810 820 830
....*....|....*....|....*....|...
gi 1907079586 1116 SQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:PTZ00121 1797 DKKIKDIFDNFANIIEGGKEGNLVINDSKEMED 1829
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
255-844 |
1.91e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 65.45 E-value: 1.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 255 DAKAKIRRLrqeLEEKTEQLLDCKQELEQIEvelkrlQQENMNLLSDARSARMYRDE----LDALREKAV-RVDKLESEL 329
Cdd:PRK02224 173 DARLGVERV---LSDQRGSLDQLKAQIEEKE------EKDLHERLNGLESELAELDEeierYEEQREQAReTRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 330 SRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLKAKLHDMEMERDMDRkkIEELM 409
Cdd:PRK02224 244 EEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE-ERDDLLAEAGLDDADAEAVEAR--REELE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 410 EEnmtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkslghevneltsskllKLEMENQSLTKTVEELRSTADSAAgs 489
Cdd:PRK02224 321 DR---DEELRDRLEECRVAAQAHNEEAESLREDAD-------------------DLEERAEELREEAAELESELEEAR-- 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 490 tSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEK-------AQLEKTIETLRENSERQIKILE----- 557
Cdd:PRK02224 377 -EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERdelrereAELEATLRTARERVEEAEALLEagkcp 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 558 ------QENEHLNQTVSSLRQRSQIsaEARVKDIEKENKILHESIkETCGKLSKIE--FEKRQMKKEL--ELYKEKGERA 627
Cdd:PRK02224 456 ecgqpvEGSPHVETIEEDRERVEEL--EAELEDLEEEVEEVEERL-ERAEDLVEAEdrIERLEERREDleELIAERRETI 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 628 EELENELNHLGKENELLQKKITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENlELR 707
Cdd:PRK02224 533 EEKRERAEELRERAAELEAEAE------EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAE 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 708 RSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrASFKKtERLEvsyqGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:PRK02224 606 DEIERLREKREALAELNDERRERLAEKRERKRELE---AEFDE-ARIE----EAREDKERAEEYLEQVEEKLDELREERD 677
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 788 DLEMENQTLQKSLEELKISSKRLEQLEKENKSLE---QETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:PRK02224 678 DLQAEIGAVENELEELEELRERREALENRVEALEalyDEAEELESMYGDLRAE---LRQR 734
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
2.02e-10 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 60.25 E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSwfDESwlSRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 94 L-QQLIMMPLPDIliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1097 |
2.27e-10 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 65.45 E-value: 2.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 256 AKAKIRRLRQELEEKTEQLLDCKQELEQIEVEL----KRLQQENMNLLSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKN---RLKEIEHNLSK 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 332 YKERLHDIEFYKARVEELKEDNQVLLETKTML-----EDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Cdd:TIGR00606 264 IMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKT 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGH-EVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:TIGR00606 344 ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 486 AAGSTSKI--------LKVEKENQRLNKKVEILENEIIQEKQ---SLQNCQNLSKDLMKEKAQL---------------E 539
Cdd:TIGR00606 424 KQEQADEIrdekkglgRTIELKKEILEKKQEELKFVIKELQQlegSSDRILELDQELRKAERELskaeknsltetlkkeV 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 540 KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDiEKENKILHESIKETCGKLSKIEFEKRQMKKELEL 619
Cdd:TIGR00606 504 KSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD-EQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSK 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 620 YKEKGERAEEL----------ENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQ- 688
Cdd:TIGR00606 583 SKEINQTRDRLaklnkelaslEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGAt 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 689 ------LESLEKENS----------QLDEENLELRRSVES-LKCASMRMAQLQLENKELESEKEQLRkGLELMRASF--- 748
Cdd:TIGR00606 663 avysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEML-GLAPGRQSIidl 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 749 --KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ---DLEMENQTLQKSLEELKISSKRLEQLEKENKS--LE 821
Cdd:TIGR00606 742 keKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsdLD 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 822 QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDI 901
Cdd:TIGR00606 822 RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLI 901
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 902 KTLVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAA 978
Cdd:TIGR00606 902 REIKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNT 981
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 979 LEARLEESTNYNQQLRHELKTVKKNYEALKQRqdeERMVQSSIPVSGEDDKWGRESQEATRELLKV-KDRLIEVERNNAT 1057
Cdd:TIGR00606 982 VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQK 1058
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 1907079586 1058 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1097
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
578-1252 |
7.22e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.93 E-value: 7.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 578 AEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERA---------------EELENELNHLGKENE 642
Cdd:TIGR02169 175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEgyellkekealerqkEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 643 LLQKKITNLKITCEKLE-TLEQENSELER----ENRKFKKTLDSFKNltfQLESLEkenSQLDEENLELRRSVESLKCAS 717
Cdd:TIGR02169 255 KLTEEISELEKRLEEIEqLLEELNKKIKDlgeeEQLRVKEKIGELEA---EIASLE---RSIAEKERELEDAEERLAKLE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 718 MRMAQLQLENKELESEKEQLRKGLELMRASFKKT----ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMEN 793
Cdd:TIGR02169 329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELkeelEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 794 QTLQkslEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQaeikdttLEENNVKIGNLEKENKTLFKEI 873
Cdd:TIGR02169 409 DRLQ---EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK-------LEQLAADLSKYEQELYDLKEEY 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 874 NVYKEscvRLKELEKENKELVKRATIdiktlvtLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR 953
Cdd:TIGR02169 479 DRVEK---ELSKLQRELAEAEAQARA-------SEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNR 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 954 YKLLESKLESTLKKSLEI-KEEKIAAL------EARLEES-----------------TNYNQQLRHELK------TVKKN 1003
Cdd:TIGR02169 549 LNNVVVEDDAVAKEAIELlKRRKAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVED 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1004 YEALKQRQDEERMV--------QSSIPVSGEDDKWGRESQEATR--ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:TIGR02169 629 IEAARRLMGKYRMVtlegelfeKSGAMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELS 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1074 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLY 1153
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1154 DAL-------IKDH-EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEK 1225
Cdd:TIGR02169 786 ARLshsripeIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE 865
|
730 740 750
....*....|....*....|....*....|.
gi 1907079586 1226 MLLESKNHEV----VASEYKKLCGENDRSRY 1252
Cdd:TIGR02169 866 LEEELEELEAalrdLESRLGDLKKERDELEA 896
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1073 |
7.74e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 7.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 575 QISAEARVKDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAE-ELENELNHLGKENELLQKKITNLKI 653
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAE-------LEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 654 TCEKLETLEQENSELERENRKFKKTLdsfKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESE 733
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQL---EELEEAEEALLERLERLEEELEELEEALAEL-----EEEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK--------- 804
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavav 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 805 -ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENnvKIGNLEKENKTLFKEINVYKESCVRL 883
Cdd:COG1196 529 lIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD--KIRARAALAAALARGAIGAAVDLVAS 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 884 KELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQqmNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRykLLESKLES 963
Cdd:COG1196 607 DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL--AGRLREVTLEGEGGSAGGSLTGGSRRELLAAL--LEAEAELE 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 964 TLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgeddkwgRESQEATRELLK 1043
Cdd:COG1196 683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL------------EELLEEEELLEE 750
|
570 580 590
....*....|....*....|....*....|
gi 1907079586 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG1196 751 EALEELPEPPDLEELERELERLEREIEALG 780
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
278-1085 |
1.03e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 63.07 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 278 KQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKavrvdKLESELSRYKERLHDIEFYKARVEELKEDNQVLL 357
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYY-----QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 358 ETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 438 RTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELR---STADSAAGSTSKILKVEKENQRLNKKVEILENEI 514
Cdd:pfam02463 328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQleeELLAKKKLESERLSSAAKLKEEELELKSEEEKEA 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 515 IQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQrsqisAEARVKDIEKENKILHE 594
Cdd:pfam02463 408 QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL-----ELKKSEDLLKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 595 SIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRK 674
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 675 FKKtldSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQL-ENKELESEKEQLRKGLELMRASFKKTER 753
Cdd:pfam02463 563 RQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAKVVEGILKDTELTKLKE 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 754 LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:pfam02463 640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 834 LEKENKRLRQQAEIKDTTLEENNVKIGNlEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVS 913
Cdd:pfam02463 720 EELLADRVQEAQDKINEELKLLKQKIDE-EEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 914 EKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK--KSLEIKEEKIAALEARLEESTNYNQ 991
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLaeEELERLEEEITKEELLQELLLKEEE 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 992 QLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEA-TRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1070
Cdd:pfam02463 879 LEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKeEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
810
....*....|....*
gi 1907079586 1071 QLETQNNNLQAQILA 1085
Cdd:pfam02463 959 EERNKRLLLAKEELG 973
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-676 |
1.12e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 63.21 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 182 SQEDIEPLLKNMVSHLRRLIDErdeHSETIVELSEERDGvhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 259 KIRRLRQELEEKTEQLLDCKQELEqievelKRLQQENmnllSDARSARMYRDEL--------DALREKAVRVDKLESELS 330
Cdd:pfam15921 325 TVSQLRSELREAKRMYEDKIEELE------KQLVLAN----SELTEARTERDQFsqesgnldDQLQKLLADLHKREKELS 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 331 RYKE---RLHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL-HDMEMER 398
Cdd:pfam15921 395 LEKEqnkRLWDrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 399 DMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELAEApqkslghEVNELTSSKLLKLEmENQSLTKTVEE 478
Cdd:pfam15921 475 EMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHLKNEGDH 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 479 LRStadsaAGSTSKILKVEKENQrlNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQIKILEQ 558
Cdd:pfam15921 543 LRN-----VQTECEALKLQMAEK--DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQEFKILKD 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 559 ENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKekgeraeeleNELNHLG 638
Cdd:pfam15921 615 KKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------NELNSLS 673
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 1907079586 639 KENELLQKKITN----LKITCEKLET-LEQENSELERENRKFK 676
Cdd:pfam15921 674 EDYEVLKRNFRNkseeMETTTNKLKMqLKSAQSELEQTRNTLK 716
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
287-878 |
1.25e-09 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 63.00 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYkerlhdiefykarVEELKEDNQVLLETKTMLEDQ 366
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMaqkqsmdeslhlgwELEQISRTSELAEap 446
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM--------------ELEKNNYYKELEE-- 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 447 qkslghEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEkENQRLNKKVEILENEIIQEKQSLQNCQN 526
Cdd:PRK01156 281 ------RHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYH-AIIKKLSVLQKDYNDYIKKKSRYDDLNN 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 527 LSKDLMKEKAQLEKTIETLrENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilheSIKETCGKLSKI 606
Cdd:PRK01156 354 QILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKVSSL 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 607 EFEKRQMKKELE-----------------------------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEK 657
Cdd:PRK01156 429 NQRIRALRENLDelsrnmemlngqsvcpvcgttlgeeksnhIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEY 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 658 LETLEQENSE--------LERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSveslkcaSMRMAQLQLENKE 729
Cdd:PRK01156 509 LESEEINKSIneynkiesARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRT-------SWLNALAVISLID 581
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 730 LESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKR 809
Cdd:PRK01156 582 IETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAE 661
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 810 LEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRLRQQAEIKDTTLEENNVKIGNLEKE---NKTLFKEINVYKE 878
Cdd:PRK01156 662 IDSIIPDLKEITSRINDIEDNLKKSRKAlddakanRARLESTIEILRTRINELSDRINDINETlesMKKIKKAIGDLKR 740
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
2.57e-09 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 61.24 E-value: 2.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 263 LRQELEEKTEQLL-------DCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 395 EMERDMDRKKIEELMEENMTLEMAQKQSmDESLHLGWELEQISRTSELAEAPQKSLghEVNEltssKLLKLEMENQSLTK 474
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQ-AELSQADALLSPSSDPGDNLAAEIMPA--EIRE----KLIRLQHENKMLRL 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 475 TVE--------ELRSTADSAAGSTSKIlkvEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLR 546
Cdd:pfam05622 297 GQEgsyrerltELQQLLEDANRRKNEL---ETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLH 373
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1907079586 547 E-NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 374 EaQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
769-1246 |
2.98e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 61.62 E-value: 2.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEnkrlrqqaeik 848
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER----------- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 849 dttLEENNVKIGNLEKENKTLfKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Cdd:PRK03918 268 ---IEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 929 THELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIK--EEKIAALEARLEESTNYNQQLRHELKTVKKNYEA 1006
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEklEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1007 LKQRQDEERMVQSSIPVSG---EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnlQAQI 1083
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK--------ESEL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1084 LALQRQTVSLQEQNTTLQTQNA-KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEK 1162
Cdd:PRK03918 496 IKLKELAEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1163 LELLHERQASEYESLISKHGTLKSAHKnlevehkdledRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKK 1242
Cdd:PRK03918 576 LKELEELGFESVEELEERLKELEPFYN-----------EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE 644
|
....
gi 1907079586 1243 LCGE 1246
Cdd:PRK03918 645 LRKE 648
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
376-856 |
3.22e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 61.30 E-value: 3.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 376 KLHELEKENLQLKAKLHDMEMERDMDRKKIE---ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEApqkslgh 452
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELEHKRARIELEkkaSALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQA------- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 453 EVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKiLKVEKENQRLNKKVEILENEIIQEKQSLQ--NCQNLSkd 530
Cdd:pfam05557 76 ELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSE-LRRQIQRAELELQSTNSELEELQERLDLLkaKASEAE-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 531 lmKEKAQLEKTIETLRENsERQIKILEQENEhlNQTVSSLRQRSQISAEARVKDIEKENKILHESIK---ETCGKLSKIE 607
Cdd:pfam05557 153 --QLRQNLEKQQSSLAEA-EQRIKELEFEIQ--SQEQDSEIVKNSKSELARIPELEKELERLREHNKhlnENIENKLLLK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 608 FEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTF 687
Cdd:pfam05557 228 EEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTSSAR 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 688 QLES----LEKENSQLDEENLELRRSVESLKCASMRMA-QLQLENKELESEKEQLR---KGLELMRASFKKTERLEVSYQ 759
Cdd:pfam05557 308 QLEKarreLEQELAQYLKKIEDLNKKLKRHKALVRRLQrRVLLLTKERDGYRAILEsydKELTMSNYSPQLLERIEEAED 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 760 GLdtenQRLQKALENSNKKIQQLESELQDLEMENQTLqksleELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Cdd:pfam05557 388 MT----QKMQAHNEEMEAQLSVAEEELGGYKQQAQTL-----ERELQALRQQESLADPSYSKEEVDSLRRKLETLELERQ 458
|
490
....*....|....*..
gi 1907079586 840 RLRQQAEIKDTTLEENN 856
Cdd:pfam05557 459 RLREQKNELEMELERRC 475
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1246 |
4.20e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 61.29 E-value: 4.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETCGKLSKIEFEKRQMkkeLELYKEKGERAEELENELN 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 636 HLGKENELLQkkitnlkitCEKLETLEQENSELErenrKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 716 ASMRMAQLQLEnKELESEKEQLR-------KGLELMRA-SFKKTERLevsyqgLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 788 DLEMENQTLQKSLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 863 EKENKTLFKEIN-VYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKiglN 938
Cdd:pfam15921 369 SQESGNLDDQLQkLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG---Q 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 939 KERLLHDEQSTDDSRYKL--LESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEA-------LKQ 1009
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVssLTAQLEST-KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAtnaeitkLRS 524
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1010 RQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQa 1081
Cdd:pfam15921 525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR- 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1082 qiLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHE 1161
Cdd:pfam15921 604 --LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1162 KLELLHERQASEYESLISK-HGTLKSAHKNLEVEHKDLED--------------RYNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:pfam15921 678 VLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSmegsdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAM 757
|
730 740
....*....|....*....|
gi 1907079586 1227 LLESKNHEVVASEYKKLCGE 1246
Cdd:pfam15921 758 TNANKEKHFLKEEKNKLSQE 777
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-838 |
6.96e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.54 E-value: 6.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 203 ERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 280 ELEQIEVELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 435 QISRTSELAEAPQKSlghevneltSSKLLKLEMENqsltKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 515 IQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIkileqENEHLNQTVSSLRQRSQISAEARVKdiEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAE 1623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 595 SIKetcgklsKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRK 674
Cdd:PTZ00121 1624 ELK-------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 675 FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR--KGLELMRASFKKTE 752
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAhlKKEEEKKAEEIRKE 1776
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSkrLEQLEKENKSLEQETSQLEKDKK 832
Cdd:PTZ00121 1777 KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSA--IKEVADSKNMQLEEADAFEKHKF 1854
|
....*.
gi 1907079586 833 QLEKEN 838
Cdd:PTZ00121 1855 NKNNEN 1860
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
264-670 |
9.34e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.07 E-value: 9.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 264 RQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESELSRYKERlhdIEFYK 343
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAE---VEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 344 ARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL--EMAQKQ 421
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAE---EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 422 SMDESLH-----LGWELEQISRTSELAEAPQKSLGHEVNELTSSkLLKLEMENQSLTKTVEELRSTADSAagstskilkv 496
Cdd:TIGR02168 824 ERLESLErriaaTERRLEDLEEQIEELSEDIESLAAEIEELEEL-IEELESELEALLNERASLEEALALL---------- 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN-SERQIKILEQENEHLNQTVSSLRQrsq 575
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEE--- 969
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 576 isAEARVKDIEKEnkilhesIKEtcgkLSKIEFEKrqmkkeLELYKEKGERAEELENELNHLGKENELLQKKITNLKITC 655
Cdd:TIGR02168 970 --ARRRLKRLENK-------IKE----LGPVNLAA------IEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREA 1030
|
410
....*....|....*..
gi 1907079586 656 EK--LETLEQENSELER 670
Cdd:TIGR02168 1031 RErfKDTFDQVNENFQR 1047
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
628-1226 |
1.12e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 59.65 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 628 EELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfqleSLEKENSQLDEENLELR 707
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLND---------KLKKNKDKINKLNSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 708 RSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEKEKL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 788 DLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:TIGR04523 184 NIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 868 TLfkeinvykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERllhdeq 947
Cdd:TIGR04523 264 KI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK------ 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 948 stddsrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQrqdeermvqssipvsged 1027
Cdd:TIGR04523 305 ----------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES------------------ 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1028 dkwgrESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1107
Cdd:TIGR04523 357 -----ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERL 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1108 QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSA 1187
Cdd:TIGR04523 432 KETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK 511
|
570 580 590
....*....|....*....|....*....|....*....
gi 1907079586 1188 HKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:TIGR04523 512 VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD 550
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1089 |
1.48e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 59.42 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARsarmyrDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE------EETAQKNNALKKIRELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 341 FYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDmemerdmdrkkiEELMEENMTLEMAQ 419
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKKALEE------------ETRSHEAQLQEMRQ 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 420 K--QSMDEslhLGWELEQISRTSELAEAPQKSLGHEVNELTSskllKLEMENQSLTKTVEELRSTADSAAGSTSKILKVE 497
Cdd:pfam01576 353 KhtQALEE---LTEQLEQAKRNKANLEKAKQALESENAELQA----ELRTLQQAKQDSEHKRKKLEGQLQELQARLSESE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 498 KENQRLNKKVEILENEIIQEKQSLQN----CQNLSKDLMKEKAQLEKTIETLRENSeRQIKILEQENEHLNQTVSSLRQR 573
Cdd:pfam01576 426 RQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKDVSSLESQLQDTQELLQEET-RQKLNLSTRLRQLEDERNSLQEQ 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 574 SQISAEARvKDIEKENKILHESIKETCGKLSK-------IEFEKRQMKKELELykeKGERAEELENELNHLGKENELLQK 646
Cdd:pfam01576 505 LEEEEEAK-RNVERQLSTLQAQLSDMKKKLEEdagtleaLEEGKKRLQRELEA---LTQQLEEKAAAYDKLEKTKNRLQQ 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 647 KITNLKItceKLETLEQENSELERENRKFKKTLDSFKNLTFQL----ESLEKENSQLDEENLELRRSVESLKCA------ 716
Cdd:pfam01576 581 ELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerDRAEAEAREKETRALSLARALEEALEAkeeler 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 717 SMRMAQLQLEN------------KELESEKEQLRKGLELMRASFKKTE-----------RLEVSYQGLDTENQR-LQKAL 772
Cdd:pfam01576 658 TNKQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedaklRLEVNMQALKAQFERdLQARD 737
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 773 ENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQLEKENKRL 841
Cdd:pfam01576 738 EQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDLQRELEEA 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 842 RQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVyKESCVRLKELEKE-------NKELVKRATIDIK-----TLVTLRE 909
Cdd:pfam01576 818 RASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrleaRIAQLEE 896
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 910 DLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLL---------HDEQSTDDSRYKL--LESKLESTLKKSLEIKEEKI 976
Cdd:pfam01576 897 ELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTsqksesarqQLERQNKELKAKLqeMEGTVKSKFKSSIAALEAKI 976
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 977 AALEARLEESTNYNQQLRHEL-KTVKKNYEALKQRQDEERMVqssipvsgedDKWGRESQEATRELLKVKDRLIEVERNN 1055
Cdd:pfam01576 977 AQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHA----------DQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
|
890 900 910
....*....|....*....|....*....|....
gi 1907079586 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam01576 1047 SRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
614-1252 |
1.98e-08 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 58.94 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 614 KKELELYKEKGERaEELENELNHlgKENELLQKKITNLK-----ITCEKLETLEQENSELERENRKFKKTLDSFKNLTfq 688
Cdd:COG5022 821 KLQKTIKREKKLR-ETEEVEFSL--KAEVLIQKFGRSLKakkrfSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS-- 895
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 689 leSLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKG-LELMRASFKKTERLEVSYQGLDTENQR 767
Cdd:COG5022 896 --SLKLVNLELESEIIELKKSLSSD-----LIENLEFKTELIARLKKLLNNIdLEEGPSIEYVKLPELNKLHEVESKLKE 968
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 768 LQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:COG5022 969 TSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPL 1048
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 848 KD----TTLEEN----NVKIGNLEKENKTLFK------EINVYKESCVRLKELEKENKELVKratiDIKTLVTLREDLVS 913
Cdd:COG5022 1049 QKlkglLLLENNqlqaRYKALKLRRENSLLDDkqlyqlESTENLLKTINVKDLEVTNRNLVK----PANVLQFIVAQMIK 1124
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 914 EKLKtQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEekiAALEARLEESTNYNQ 991
Cdd:COG5022 1125 LNLL-QEISKFLSQLVNTLEPVfqKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQS---ALYDEKSKLSSSEVN 1200
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 992 QLRHELKTVKKNYEALKQRQDEERMVQS--------SIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQ 1063
Cdd:COG5022 1201 DLKNELIALFSKIFSGWPRGDKLKKLISegwvpteySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEE 1280
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1064 ALKTQLKQLETQNNNLQAQILALQRQTVSLQ-----EQNTTLQtQNAKLQVENSTLNSQSTSLMnqNAQLLIQqssLENE 1138
Cdd:COG5022 1281 VLPATINSLLQYINVGLFNALRTKASSLRWKsatevNYNSEEL-DDWCREFEISDVDEELEELI--QAVKVLQ---LLKD 1354
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1139 NESIMKEREDL-KSLYDALIKdheklELLHERQASEYEsliskHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQlEDLEK 1217
Cdd:COG5022 1355 DLNKLDELLDAcYSLNPAEIQ-----NLKSRYDPADKE-----NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHLSE 1423
|
650 660 670
....*....|....*....|....*....|....*
gi 1907079586 1218 MIKTEqEKMLLESKNHEVVASEYKKLCGENDRSRY 1252
Cdd:COG5022 1424 IFSEE-KSLISLDRNSIYKEEVLSSLSALLTKEKI 1457
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
2.68e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 58.51 E-value: 2.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 201 IDERDEHSETIVELSEERDGVhflphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQlldCKQE 280
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEE---LRDR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 281 LEQIEVELKRLQQENMNLLSDARSArmyRDELDALREKAvrvDKLESELSRYKErlhDIEFYKARVEELKEDNQVLLETK 360
Cdd:PRK02224 330 LEECRVAAQAHNEEAESLREDADDL---EERAEELREEA---AELESELEEARE---AVEDRREEIEELEEEIEELRERF 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 361 TMLEDQLEGTRARSDKLHElekenlqLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK-----QSMDESLHLGWELEQ 435
Cdd:PRK02224 401 GDAPVDLGNAEDFLEELRE-------ERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEED 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 436 ISRTSELaEAPQKSLGHEVNEL-----TSSKLLKLEMENQSL---TKTVEELRSTA-DSAAGSTSKILKVEKENQRLNKK 506
Cdd:PRK02224 474 RERVEEL-EAELEDLEEEVEEVeerleRAEDLVEAEDRIERLeerREDLEELIAERrETIEEKRERAEELRERAAELEAE 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 507 VEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIleqenEHLNQTVSSLRQRSQISAEarVKDIE 586
Cdd:PRK02224 553 AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI-----ADAEDEIERLREKREALAE--LNDER 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 587 KEN-KILHESIKETCGKLSKIEFEK-RQMKKELELYKEK-GERAEELENELNHL-----GKENEL-----LQKKITNLKI 653
Cdd:PRK02224 626 RERlAEKRERKRELEAEFDEARIEEaREDKERAEEYLEQvEEKLDELREERDDLqaeigAVENELeeleeLRERREALEN 705
|
490
....*....|....*.
gi 1907079586 654 TCEKLETLEQENSELE 669
Cdd:PRK02224 706 RVEALEALYDEAEELE 721
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
474-1226 |
2.69e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.52 E-value: 2.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 474 KTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIiqekqsLQNCQNLSKDLMKEKAQLEKTIETLRENSERQI 553
Cdd:TIGR00606 255 KEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV------FQGTDEQLNDLYHNHQRTVREKERELVDCQREL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 554 KILEQENEHLNQTVSSL---RQRSQISAEARVKDIEK-ENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEE 629
Cdd:TIGR00606 329 EKLNKERRLLNQEKTELlveQGRLQLQADRHQEHIRArDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAK 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 630 LENEL-NHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:TIGR00606 409 TAAQLcADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELS 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 708 RSVE--SLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESE 785
Cdd:TIGR00606 489 KAEKnsLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGY 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 786 LQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeIKDTTLEENNVKIGNLEKE 865
Cdd:TIGR00606 569 FPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEE 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 866 NKTLFKEINVykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEklthelekiglNKERLLHD 945
Cdd:TIGR00606 648 IEKSSKQRAM-------LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQ-----------SKLRLAPD 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 946 EQSTDDSRYKLLESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSG 1025
Cdd:TIGR00606 710 KLKSTESELKKKEKRRDEMLGL-APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCL 788
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1026 EDDKWGRESQEATRELLKVKDRLIEvERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Cdd:TIGR00606 789 TDVTIMERFQMELKDVERKIAQQAA-KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTN 867
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKD-HEKLELLHERQASE----------Y 1174
Cdd:TIGR00606 868 ELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDqQEKEELISSKETSNkkaqdkvndiK 947
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 1175 ESLISKHGTLKSAHKNLEVEHKD-LEDRYNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:TIGR00606 948 EKVKNIHGYMKDIENKIQDGKDDyLKQKETELNTVNAQLEECEKHQEKINEDM 1000
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1013 |
3.01e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.52 E-value: 3.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESELSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 480 RSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 554 KILEQENEHLNQtvsSLRQRSQISAEARVKD-IEKENKILHESIKETCGKLSKIEFEKRQMKKELE-LYKEKGERAEELE 631
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYSqFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQsKLRLAPDKLKSTE 715
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 632 NELNHLGKENELLqkkITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfqleSLEKENSQLDEENLELRrSVE 711
Cdd:TIGR00606 716 SELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEEE-SAK 785
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 712 SLKCASMRMAQLQLENKELESEKEQLRKGLELMRASF------KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESE 785
Cdd:TIGR00606 786 VCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRtvqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSK 865
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 786 LQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:TIGR00606 866 TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 866 NKTLFKEINVYkescvrLKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLnKERLLH 944
Cdd:TIGR00606 946 IKEKVKNIHGY------MKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI-QERWLQ 1018
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 945 DEQSTDDSRYKLLEskLESTLKKSLEikeekiAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDE 1013
Cdd:TIGR00606 1019 DNLTLRKRENELKE--VEEELKQHLK------EMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
639-1076 |
3.25e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.86 E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 639 KENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLkcasm 718
Cdd:COG4717 54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL----- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 719 rmaQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKI-QQLESELQDLEMENQTLQ 797
Cdd:COG4717 129 ---PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQ 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 798 KSLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEENNVKIGN---- 861
Cdd:COG4717 206 QRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLILTIAGvlfl 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 862 -----------LEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG4717 282 vlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 931 ELEKIGLNKER--LLHDEQSTDDSRYkllESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ---------QLRHELKT 999
Cdd:COG4717 362 ELQLEELEQEIaaLLAEAGVEDEEEL---RAALE--QAEEYQELKEELEELEEQLEELLGELEellealdeeELEEELEE 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907079586 1000 VKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1076
Cdd:COG4717 437 LEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
249-570 |
5.84e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.39 E-value: 5.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsdarsarmYRDELDALREkavRVDKLESE 328
Cdd:TIGR02169 707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA---RIEELEED 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 329 LSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKLHDMEMERDMDR 402
Cdd:TIGR02169 774 LHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQRIDLKEQIKSIE 853
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 403 KKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTK-------- 474
Cdd:TIGR02169 854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKlealeeel 933
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 475 -TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILE---NEIIQEKQSLQNCQNLSKD----LMKEKAQLEKTIETLr 546
Cdd:TIGR02169 934 sEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEERKAILERIEEY- 1012
|
330 340
....*....|....*....|....*.
gi 1907079586 547 ENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1013 EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
136-846 |
7.73e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 56.90 E-value: 7.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 136 QKKEEFIEKIQGLD-FDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPL---LKNMVSHLRRLIDERDEHSETI 211
Cdd:TIGR00618 163 KEKKELLMNLFPLDqYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYherKQVLEKELKHLREALQQTQQSH 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 212 VELSEERDgvhfLPHASSSAQSPCGSPGMKRTESR-QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKR 290
Cdd:TIGR00618 243 AYLTQKRE----AQEEQLKKQQLLKQLRARIEELRaQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQS 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 291 LQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370
Cdd:TIGR00618 319 KMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSL 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 371 RARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhlgwelEQISRTSELAEAPQKSL 450
Cdd:TIGR00618 399 CKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ---------CEKLEKIHLQESAQSLK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 451 GHEVNELTSSKLLKLEMEnqslTKTVEElrstadsaagstsKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD 530
Cdd:TIGR00618 470 EREQQLQTKEQIHLQETR----KKAVVL-------------ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 531 LMKEKAQLEKTIETLR---ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIE 607
Cdd:TIGR00618 533 GEQTYAQLETSEEDVYhqlTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 608 FEKRQMKK------ELELYKEKGERAEELENELNHLGKENELLQKKitnlKITCEKLETLEQENSELERENRKFKKTLDS 681
Cdd:TIGR00618 613 EQHALLRKlqpeqdLQDVRLHLQQCSQELALKLTALHALQLTLTQE----RVREHALSIRVLPKELLASRQLALQKMQSE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 682 FKNLTFQLESLEKENSQLDEEN---LELRRSVESLKCASMRM-----AQLQLENKELESEKEQLRKGL-ELMRASFKKTE 752
Cdd:TIGR00618 689 KEQLTYWKEMLAQCQTLLRELEthiEEYDREFNEIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNE 768
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 753 RLEVSYQgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKEN--KSLEQETSQLEKD 830
Cdd:TIGR00618 769 EVTAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQflSRLEEKSATLGEI 847
|
730
....*....|....*.
gi 1907079586 831 KKQLEKENKRLRQQAE 846
Cdd:TIGR00618 848 THQLLKYEECSKQLAQ 863
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
683-1218 |
1.09e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.59 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 683 KNLTFQLESLEKENSQLDEE----NLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERL--EV 756
Cdd:PRK02224 202 KDLHERLNGLESELAELDEEieryEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELaeEV 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 757 SYQ-----GLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQlekenksleqETSQLEKDK 831
Cdd:PRK02224 282 RDLrerleELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNE----------EAESLREDA 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEInvykescvrlkeleKENKELVKRATIDIKTLVTLREDL 911
Cdd:PRK02224 352 DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI--------------EELRERFGDAPVDLGNAEDFLEEL 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD------EQSTDDS-RYKLLESKLE--STLKKSLEIKEEKIAALEAR 982
Cdd:PRK02224 418 REERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEGSpHVETIEEDRErvEELEAELEDLEEEVEEVEER 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 983 LEESTNYnQQLRHELKTVKKNYEALKQRQDEER--------MVQSSIPVSGEDDKWGRESQEATRELlkvKDRLIEVERN 1054
Cdd:PRK02224 498 LERAEDL-VEAEDRIERLEERREDLEELIAERRetieekreRAEELRERAAELEAEAEEKREAAAEA---EEEAEEAREE 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1055 NATLQAEKQALKTQLKQLETQNNnLQAQILALQRQTVSLQEQNTTLQTQNAKlqvENSTLNSQSTSlmnqnaqllIQQSS 1134
Cdd:PRK02224 574 VAELNSKLAELKERIESLERIRT-LLAAIADAEDEIERLREKREALAELNDE---RRERLAEKRER---------KRELE 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1135 LENENESIMKEREDLKSLYDALIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEV---EHKDLEDRYNQLLKQKGQ 1211
Cdd:PRK02224 641 AEFDEARIEEAREDKERAEEYLEQVEEKLDELREER----DDLQAEIGAVENELEELEElreRREALENRVEALEALYDE 716
|
....*..
gi 1907079586 1212 LEDLEKM 1218
Cdd:PRK02224 717 AEELESM 723
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-873 |
1.27e-07 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 55.67 E-value: 1.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE--ARVKDIEKENKILHESIKE 598
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREkhEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 599 TCGKLSKIEFEKRQMKKELEL-YKEKGERAEELENELNHLGKEnellQKKITNLKitcekletlEQENSELERENRKFKK 677
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------KEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVS 757
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 758 YQGLDTENQRLQKALENSNKKIQQLESELQDLEM-----------ENQTLQKSLEELKISSKRL-EQLEKENKSLEQETS 825
Cdd:pfam07888 260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLsAELQRLEERLQEERM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1907079586 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:pfam07888 340 EREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1231 |
1.33e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 56.34 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEkNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 341 fykARVEELKEDNQVLL-ETKTM------LEDQLEGTRARSDKLHeLEKENLQLKAK--------LHDMEMERDMDRKKI 405
Cdd:pfam01576 82 ---SRLEEEEERSQQLQnEKKKMqqhiqdLEEQLDEEEAARQKLQ-LEKVTTEAKIKkleedillLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 406 EE--------LMEENMTLEMAQK-----QSMDESLHLGWELEQISRtSELAEAPQKSLGH--EVNELTSSKLLKLEMENQ 470
Cdd:pfam01576 158 EEriseftsnLAEEEEKAKSLSKlknkhEAMISDLEERLKKEEKGR-QELEKAKRKLEGEstDLQEQIAELQAQIAELRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 471 SLTKTVEELRST---ADSAAGSTSKILKVEKENQRLNKKV-EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIET-- 544
Cdd:pfam01576 237 QLAKKEEELQAAlarLEEETAQKNNALKKIRELEAQISELqEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTta 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 545 ----LRENSERQI----KILEQENEHLNQTVSSLRQ-----------------RSQISAEARVKDIEKENKILHESIKET 599
Cdd:pfam01576 317 aqqeLRSKREQEVtelkKALEEETRSHEAQLQEMRQkhtqaleelteqleqakRNKANLEKAKQALESENAELQAELRTL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 600 CGKLSKIEFEKRQMKKELE-----------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSEL 668
Cdd:pfam01576 397 QQAKQDSEHKRKKLEGQLQelqarlseserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQEL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 669 ERENRKFKktldsfKNLTFQLESLEKENSQLDE---ENLELRRSVESlkcasmrmaQLQLENKELESEKeqlrkglelmr 745
Cdd:pfam01576 477 LQEETRQK------LNLSTRLRQLEDERNSLQEqleEEEEAKRNVER---------QLSTLQAQLSDMK----------- 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 746 asfKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:pfam01576 531 ---KKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFD 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 826 QLEKDKKQLEKENKRLRQQAEIKDTtleennvkignlEKENKTLfkeinvykeSCVRLKELEKENKELVKRATidiKTLV 905
Cdd:pfam01576 608 QMLAEEKAISARYAEERDRAEAEAR------------EKETRAL---------SLARALEEALEAKEELERTN---KQLR 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 906 TLREDLVSEKLKTQQMNNDLEK----LTHELEKIGLNKERLLHDEQSTDDSRYKL------LESKLESTLKKSLEIKEEK 975
Cdd:pfam01576 664 AEMEDLVSSKDDVGKNVHELERskraLEQQVEEMKTQLEELEDELQATEDAKLRLevnmqaLKAQFERDLQARDEQGEEK 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 976 IAALEARLEEstnYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwGREsqEATRELLKVKDRLIEVERNN 1055
Cdd:pfam01576 744 RRQLVKQVRE---LEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANK----GRE--EAVKQLKKLQAQMKDLQREL 814
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSL 1135
Cdd:pfam01576 815 EEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQL 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1136 ENENESIMKEREDLKSLYDALIKDHEKL--ELLHERQASEyesliskhgTLKSAHKNLEVEHKDLEDRYNQL-----LKQ 1208
Cdd:pfam01576 895 EEELEEEQSNTELLNDRLRKSTLQVEQLttELAAERSTSQ---------KSESARQQLERQNKELKAKLQEMegtvkSKF 965
|
1050 1060
....*....|....*....|...
gi 1907079586 1209 KGQLEDLEKMIKTEQEKMLLESK 1231
Cdd:pfam01576 966 KSSIAALEAKIAQLEEQLEQESR 988
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
252-927 |
1.52e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.13 E-value: 1.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRvDKLESELSR 331
Cdd:pfam02463 353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLK-EEKKEELEI 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 332 YKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:pfam02463 432 LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKV 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTS 491
Cdd:pfam02463 512 LLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPL 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 492 KILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:pfam02463 592 KSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL 671
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 572 QRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKEN--ELLQKKIT 649
Cdd:pfam02463 672 TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLkqKIDEEEEE 751
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 650 NLKITCEKLETLEQENSELERENRKFKKTLDSFKNLtfqLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKE 729
Cdd:pfam02463 752 EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK---VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEE 828
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 730 LESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKR 809
Cdd:pfam02463 829 KIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQK 908
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQaEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE 889
Cdd:pfam02463 909 LNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE-EADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE 987
|
650 660 670
....*....|....*....|....*....|....*...
gi 1907079586 890 NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEK 927
Cdd:pfam02463 988 ERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLEL 1025
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
609-986 |
1.89e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 609 EKRQMKKELELYKEKGERAEELENELNhlgKENELLQKkitnlkitcEKLETLEQEnsELERENRKFKKTLdsfknLTFQ 688
Cdd:TIGR02169 171 KKEKALEELEEVEENIERLDLIIDEKR---QQLERLRR---------EREKAERYQ--ALLKEKREYEGYE-----LLKE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 689 LESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELEsEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQ-- 766
Cdd:TIGR02169 232 KEALERQKEAIERQLASLEEELEKLT------EEISELEKRLE-EIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEia 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 767 RLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKisskrlEQLEKENKSLEQETSQLEKDKKQLEKenkrLRQQAE 846
Cdd:TIGR02169 305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAELKEELED----LRAELE 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 847 IKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRatidiktlvtLREDLVSEKLKTQQMNNDLE 926
Cdd:TIGR02169 375 EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD----------LNAAIAGIEAKINELEEEKE 444
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 927 KLTHELEKIGLNKERLLHDEQSTDDSRYKLLE--SKLESTLKKsleiKEEKIAALEARLEES 986
Cdd:TIGR02169 445 DKALEIKKQEWKLEQLAADLSKYEQELYDLKEeyDRVEKELSK----LQRELAEAEAQARAS 502
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1158 |
2.39e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 55.30 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 796 LQKSLEELKisskRLEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKE 872
Cdd:PRK11281 41 VQAQLDALN----KQKLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 873 INvykeSCVRLKELEKE-NKELVKRATIDiKTLVTLREDLVS-----EKLKTQQMNND--LEKLTHELEKIGLNKERLLH 944
Cdd:PRK11281 117 TL----STLSLRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSlqtqpERAQAALYANSqrLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 945 DEQSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKknyEAL--KQRQDEERMVQSSIp 1022
Cdd:PRK11281 192 SQRVLLQAEQALLNAQND-LQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ---EAInsKRLTLSEKTVQEAQ- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1023 vSGEDDKWGRESQEATREL---LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL------------Q 1087
Cdd:PRK11281 267 -SQDEAARIQANPLVAQELeinLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkgslllsrilyqQ 345
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 1088 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SIMKEREDlksLYDALIK 1158
Cdd:PRK11281 346 QQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE---LLDQLNK 421
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
432-1053 |
2.47e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 55.29 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 432 ELEQISRTSELAEAPQKSLGHEVneltsSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKvekENQRLNKKVEILE 511
Cdd:PRK01156 160 EINSLERNYDKLKDVIDMLRAEI-----SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLK---EIERLSIEYNNAM 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 512 NEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL-RQRSQISAEARVK-DIEKEN 589
Cdd:PRK01156 232 DDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVyKNRNYINDYFKYKnDIENKK 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 590 KILhESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLkitcekletlEQENSELE 669
Cdd:PRK01156 312 QIL-SNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSI----------ESLKKKIE 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 670 RENRKFKKTLDSFKNLtfqLESLEKENSQLDEENLELRRSVESLkcaSMRMAQLQLENKELESEKEQLRKGLELMRAsfk 749
Cdd:PRK01156 381 EYSKNIERMSAFISEI---LKIQEIDPDAIKKELNEINVKLQDI---SSKVSSLNQRIRALRENLDELSRNMEMLNG--- 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 750 kteRLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKEN-KSLEQETSQLE 828
Cdd:PRK01156 452 ---QSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLK---KRKEYLESEEiNKSINEYNKIE 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 829 KDKKQLEKEnkrlrqqaEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvrlkelEKENKELVKRATIDIKTLVTlR 908
Cdd:PRK01156 526 SARADLEDI--------KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKR--------TSWLNALAVISLIDIETNRS-R 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 909 EDLVSEKLktqqmnNDLEKLTHELEKiglnkerLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAAlearleestn 988
Cdd:PRK01156 589 SNEIKKQL------NDLESRLQEIEI-------GFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILI---------- 645
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 989 ynQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVER 1053
Cdd:PRK01156 646 --EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILR 708
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1223 |
3.59e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 55.06 E-value: 3.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESELSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELAEAPQKSLGHEVNELTSSK-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 467 MENQSLTKTV--EELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETCGKLSKIefeKRQMKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 618 ELYKEKGERAEELENELnhlgkENELLQKKITNLKITCE-KLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 695 ENSQLDEENLELRRSVESLKCA---SMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERLEVSYQGLD------ 762
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDfgkeen 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 763 ----TENQRLQKALENSNKKIQQLESELQDLEM-------ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR01612 1107 ikyaDEINKIKDDIKNLDQKIDHHIKALEEIKKksenyidEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKK 1186
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 832 KQLEKENKRLRQQAEIK--DTTLEE-NNVKIGNLEKENKTLFKEIN-VYKESCVRLKELEKENKEL--VKRATIDIKTLV 905
Cdd:TIGR01612 1187 NIYDEIKKLLNEIAEIEkdKTSLEEvKGINLSYGKNLGKLFLEKIDeEKKKSEHMIKAMEAYIEDLdeIKEKSPEIENEM 1266
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 906 TLREDLVSEkLKTQQMNNDLEKLTHELEKiglnkerllHDEQSTDDSRYKLLESKLESTLKKSL-EIKEEkiaaLEARLE 984
Cdd:TIGR01612 1267 GIEMDIKAE-METFNISHDDDKDHHIISK---------KHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKNLL 1332
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 985 ESTNYNQQLRHELKTVKKNYEALKQRQdeermVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQA 1064
Cdd:TIGR01612 1333 DAQKHNSDINLYLNEIANIYNILKLNK-----IKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSK 1407
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1065 LKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE---N 1139
Cdd:TIGR01612 1408 IES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhdfN 1484
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1140 ESIMKERED----LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHKDLEDRYNQLLKQK 1209
Cdd:TIGR01612 1485 INELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFILEA 1564
|
1050
....*....|....
gi 1907079586 1210 GQLEDLEKMIKTEQ 1223
Cdd:TIGR01612 1565 EKSEQKIKEIKKEK 1578
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1026-1224 |
3.74e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 3.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1026 EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1098
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1099 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLI 1178
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1907079586 1179 SKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQE 1224
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
594-837 |
5.59e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 5.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENR 673
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE---EKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 674 KFKKTLDSFKN-LTFQLESLEKENSQldeENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKglelmrasfkKTE 752
Cdd:COG4942 94 ELRAELEAQKEeLAELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA----------DLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKK 832
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEAA 237
|
....*
gi 1907079586 833 QLEKE 837
Cdd:COG4942 238 AAAER 242
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
743-897 |
5.74e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 54.09 E-value: 5.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 743 LMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQ 822
Cdd:COG2433 382 LEELIEKELPEEEPEAEREKEHEERELTEEE---EEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARS 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907079586 823 ET-SQLEKDKK--QLEKENKRLRQQAEIKDTTLEENNVKignLEKENKTLFKEInvyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 456 EErREIRKDREisRLDREIERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-750 |
5.78e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 5.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 259 KIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESELSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 419 QKQSMDESLHLGWELEQISRTSELAeapqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILkvek 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLL-------------LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF---- 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 499 enqRLNKKVEILENEIIQEKQSLQNCQNLskdlmkEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:COG4717 291 ---LLLAREKASLGKEAEELQALPALEEL------EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 579 EARVKDIEKENKILHESIKETcgklSKIEFEKRQmkKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKL 658
Cdd:COG4717 362 ELQLEELEQEIAALLAEAGVE----DEEELRAAL--EQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELE-EEL 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 659 ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEK-ENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQL 737
Cdd:COG4717 435 EELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
490
....*....|...
gi 1907079586 738 RKGLELMRASFKK 750
Cdd:COG4717 515 PPVLERASEYFSR 527
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
495-1243 |
6.48e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.20 E-value: 6.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 495 KVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikileQENEHLNQTVSSLRQRS 574
Cdd:TIGR00618 195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQ-----EEQLKKQQLLKQLRARI 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 575 QiSAEARVKDIEKENKILHESIK-----ETCGKLSKIEFEKRQMKKELElyKEKGERAEELENELNHLGKENELLQKKit 649
Cdd:TIGR00618 270 E-ELRAQEAVLEETQERINRARKaaplaAHIKAVTQIEQQAQRIHTELQ--SKMRSRAKLLMKRAAHVKQQSSIEEQR-- 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 650 nlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEenlelrrSVESLKCASMRMAQLQLENKE 729
Cdd:TIGR00618 345 ------RLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTT-------LTQKLQSLCKELDILQREQAT 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 730 LESEkEQLRKGLELMRASFKKTERLEVSYQGLdtenqrlqkalensnkKIQQLESELQDLEMENQTLQKSLEELKISSKR 809
Cdd:TIGR00618 412 IDTR-TSAFRDLQGQLAHAKKQQELQQRYAEL----------------CAAAITCTAQCEKLEKIHLQESAQSLKEREQQ 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 810 LEQLEKENKSlEQETSQLEKDKKQLEKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE 889
Cdd:TIGR00618 475 LQTKEQIHLQ-ETRKKAVVLARLLELQEEPCPLCGSCIH---PNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQ 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 890 NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEkiglnkeRLLHDEQSTDDSRYKLLESKLESTLKKSL 969
Cdd:TIGR00618 551 LTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV-------RLQDLTEKLSEAEDMLACEQHALLRKLQP 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 970 EIKEEKIAALEARLEEstnynqqlRHELKTVKKNYEALKQRQDEERmvqssipvsgeddkwgrESQEATRELLKVKdrLI 1049
Cdd:TIGR00618 624 EQDLQDVRLHLQQCSQ--------ELALKLTALHALQLTLTQERVR-----------------EHALSIRVLPKEL--LA 676
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1050 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ-NAQL 1128
Cdd:TIGR00618 677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQaRTVL 756
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1129 LIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQ 1208
Cdd:TIGR00618 757 KARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSR 836
|
730 740 750
....*....|....*....|....*....|....*
gi 1907079586 1209 KGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKL 1243
Cdd:TIGR00618 837 LEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKI 871
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-934 |
7.86e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 7.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 726 ENKELESEKEQLRKGLELMRASFKKTERLEVSYQG----LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 802 ELKIS-SKRLEQLEKENKSLE-------QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:COG4942 101 AQKEElAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 874 NVYKESCVRLKELEKENKELVKRATidiKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
9.16e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 9.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 456 ELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQM 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 614 KKELELYKEKGERAEELENE-------------LNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLD 680
Cdd:COG4717 226 EEELEQLENELEAAALEERLkearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 681 SFKNLTfQLESLEKE--NSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR-KGLELMRASF--KKTERLE 755
Cdd:COG4717 306 ELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALlaEAGVEDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 756 VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKslEELKissKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:COG4717 385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELE---EELEELEEELEELEEELEELREELAELE 459
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1907079586 836 KENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:COG4717 460 AELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
547-867 |
1.28e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 52.98 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHEsiKETC-GKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:PLN02939 117 TNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTE--KEALqGKINILEMRLSETDARIKLAAQEKI 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 626 RAEELENELNHLgkENELLQKKITNLKITC---EKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDee 702
Cdd:PLN02939 195 HVEILEEQLEKL--RNELLIRGATEGLCVHslsKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLD-- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 703 nlelrrsveslkcASMRmaqlQLENKELESEKEQLRKGLELMRASFKKTERLEVsyqgldtenqRLQKALENSNKKIQQL 782
Cdd:PLN02939 271 -------------ASLR----ELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD----------LLDRATNQVEKAALVL 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 783 ESElQDLEMENQTLQKSLEE---LKISSKRLEQLEKENKSLEQetsqlekdkkQLEKENKRLRQQAEIKDTTLEENNVKI 859
Cdd:PLN02939 324 DQN-QDLRDKVDKLEASLKEanvSKFSSYKVELLQQKLKLLEE----------RLQASDHEIHSYIQLYQESIKEFQDTL 392
|
....*...
gi 1907079586 860 GNLEKENK 867
Cdd:PLN02939 393 SKLKEESK 400
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
991-1208 |
1.65e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 1.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 991 QQLRHELKTVKKNYEALKQRQDEERMVQSSIpvSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1070
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKAL--LKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1071 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1149 LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQ 1208
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1180 |
1.89e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 1.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL--FKEINVYKEScVRLKELEKENKELVKRATIDI 901
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAerYQALLKEKRE-YEGYELLKEKEALERQKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 902 KTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTlkksleikEEKIAALEA 981
Cdd:TIGR02169 244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--------ERSIAEKER 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 982 RLEESTNYNQQLRHELKTVKKNYEALKQRQDEERmvqssipvsGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE 1061
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEER---------KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1062 KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1141
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1907079586 1142 IMKEREDLKSLYDALIKDHEKLE-----LLHERQASEYESLISK 1180
Cdd:TIGR02169 467 YEQELYDLKEEYDRVEKELSKLQrelaeAEAQARASEERVRGGR 510
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-868 |
2.06e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 52.39 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESELSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPelnklHEVESKLKETSEEYEDLLKKSTILVREGNKA 990
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 416 EMAQKQSMDESLHLGWELEQISRTSELAeapqKSLGHEVNELTS-SKLLKLEMENQSLTKTVEELRSTADSAAGSTS--- 491
Cdd:COG5022 991 NSELKNFKKELAELSKQYGALQESTKQL----KELPVEVAELQSaSKIISSESTELSILKPLQKLKGLLLLENNQLQary 1066
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 492 KILKVEKENQRLNKK-------VEILENEiIQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLR--ENSERQIKILEQE 559
Cdd:COG5022 1067 KALKLRRENSLLDDKqlyqlesTENLLKT-INVKDLEVTNRNLVKPANVLqfiVAQMIKLNLLQEisKFLSQLVNTLEPV 1145
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 560 NEHLNQT---------VSSLRQRSQISAEARVKDIEKenkiLHESIKETCGKLSKIefekrqmkkELELYKEKGERAEEL 630
Cdd:COG5022 1146 FQKLSVLqleldglfwEANLEALPSPPPFAALSEKRL----YQSALYDEKSKLSSS---------EVNDLKNELIALFSK 1212
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 631 ENELNHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE--------NSQLDE 701
Cdd:COG5022 1213 IFSGWPRGDKLKKLISEGWVPTEYSTSLkGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEeevlpatiNSLLQY 1292
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 702 ENLELRRSVeSLKCASMRMAQLQLENKELESEKE-QLRKGLELMRASFKKTER----LEVSYQGLDTENQRLQKALENSN 776
Cdd:COG5022 1293 INVGLFNAL-RTKASSLRWKSATEVNYNSEELDDwCREFEISDVDEELEELIQavkvLQLLKDDLNKLDELLDACYSLNP 1371
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 777 KKIQQLESELQDLEMENQTLQKSLEELKISS--KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTleE 854
Cdd:COG5022 1372 AEIQNLKSRYDPADKENNLPKEILKKIEALLikQELQLSLEGKDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL--S 1449
|
650
....*....|....
gi 1907079586 855 NNVKIGNLEKENKT 868
Cdd:COG5022 1450 ALLTKEKIALLDRK 1463
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1225 |
2.32e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 52.21 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 725 LENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdttlEENNVKIGNLEKENKTLFKEINVYKESCVRLK 884
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELE-------ERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 885 ELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR--YKLLESKLE 962
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSVLQKDY-NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIeeYSKNIERMS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMV------QSSIPVSGE---DDKWGRE 1033
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmemlngQSVCPVCGTtlgEEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1034 SQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN----NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1109
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEinksINEYNKIESARADLEDIKIKINELKDKHDKYEE 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1110 ENSTLNSQSTSLMNQN----AQLLIQQSSLENENesIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKhgtlk 1185
Cdd:PRK01156 551 IKNRYKSLKLEDLDSKrtswLNALAVISLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIRE----- 623
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 1907079586 1186 sahknLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEK 1225
Cdd:PRK01156 624 -----IENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQ 658
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
964-1234 |
2.54e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.25 E-value: 2.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 964 TLKKSLEIKEEKIAALEARleestnynqQLRHELKTVKKNYEALKQRQDEERmvqssipvsgeddkwgRESQEATRELLK 1043
Cdd:COG1196 217 ELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELE----------------AELAELEAELEE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1123
Cdd:COG1196 272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1124 QNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYN 1203
Cdd:COG1196 352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
|
250 260 270
....*....|....*....|....*....|.
gi 1907079586 1204 QLLKQKGQLEDLEKMIKTEQEKMLLESKNHE 1234
Cdd:COG1196 432 ELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
764-1014 |
2.68e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 51.85 E-value: 2.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 764 ENQRLQKALENS---NKKIQQLESELQDLEMENQTLQ----KSLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:PRK05771 41 SNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 836 KENKRLRqqaeikdttleennvKIGNLEKENKTLFKEINVYkescVRLKELEKENKELVKrATIDIKTLVTLRED----- 910
Cdd:PRK05771 121 QEIERLE---------------PWGNFDLDLSLLLGFKYVS----VFVGTVPEDKLEELK-LESDVENVEYISTDkgyvy 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 911 --LVSEKlktqqmnNDLEKLTHELEKIGLnkerllhdeqstddSRYKLLESKlesTLKKSLEIKEEKIAALEARLEEstn 988
Cdd:PRK05771 181 vvVVVLK-------ELSDEVEEELKKLGF--------------ERLELEEEG---TPSELIREIKEELEEIEKERES--- 233
|
250 260
....*....|....*....|....*.
gi 1907079586 989 ynqqLRHELKTVKKNYEALKQRQDEE 1014
Cdd:PRK05771 234 ----LLEELKELAKKYLEELLALYEY 255
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
434-1016 |
2.71e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 52.03 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 434 EQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQ--SLTKTVEELRSTADSAAGSTskilKVEKEN-QRLNKKVEIL 510
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 511 ENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLrqrsqisaEARVKDIEKENK 590
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF--------EATTCSLEELLR 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 591 ILHESIKETCGKLSKIEFEKRQMKKELE-LYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKLETLEQENSELE 669
Cdd:pfam05483 367 TEQQRLEKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIA-EELKGKEQELIFLL 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 670 RENRKfkktldSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMA----QLQLENKELESEKEQLRKGLELMR 745
Cdd:pfam05483 446 QAREK------EIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTahcdKLLLENKELTQEASDMTLELKKHQ 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 746 ASFKKTERLEvsyqgldtenQRLQKALENSNKKIQQLESELQDLEMEnqtLQKSLEELKIsskRLEQLEKENKSLEQETS 825
Cdd:pfam05483 520 EDIINCKKQE----------ERMLKQIENLEEKEMNLRDELESVREE---FIQKGDEVKC---KLDKSEENARSIEYEVL 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESC----VRLKELEKENKELVKRATIDI 901
Cdd:pfam05483 584 KKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVnkleLELASAKQKFEEIIDNYQKEI 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 902 KTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEA 981
Cdd:pfam05483 664 EDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAA 743
|
570 580 590
....*....|....*....|....*....|....*
gi 1907079586 982 RLEESTNynqqLRHELKTVKKNYEALKQRQDEERM 1016
Cdd:pfam05483 744 LEIELSN----IKAELLSLKKQLEIEKEEKEKLKM 774
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
257-664 |
4.33e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 4.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSarmyrdeldALREKAVRVDKLESELSRYKERL 336
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE----LSDASR---------KIGEIEKEIEQLEQEEEKLKERL 739
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 337 HDIEfykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqlkaklhDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR02169 740 EELE------EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA---------LNDLEARLSHSRIPEIQAELSKLE 804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 417 maqkqsmdeslhlgwelEQISRTSELAEAPQKSLGhevneltsskllKLEMENQSLTKTVEELRSTADSAagsTSKILKV 496
Cdd:TIGR02169 805 -----------------EEVSRIEARLREIEQKLN------------RLTLEKEYLEKEIQELQEQRIDL---KEQIKSI 852
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 497 EKENQRLNKKVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKTIETLR---ENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR02169 853 EKEIENLNGKKEELEEE-------LEELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRLSELKAK 925
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 574 SQIsAEARVKDIEKENKILhESIKETCGKLSKIEFEKRQMKKELELYKEKGERA----EELENELNHLGKENELLQKKIT 649
Cdd:TIGR02169 926 LEA-LEEELSEIEDPKGED-EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyEEVLKRLDELKEKRAKLEEERK 1003
|
410
....*....|....*
gi 1907079586 650 NLKITCEKLETLEQE 664
Cdd:TIGR02169 1004 AILERIEEYEKKKRE 1018
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
666-1107 |
4.83e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 4.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 666 SELERENRK-FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELm 744
Cdd:COG4717 49 ERLEKEADElFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 745 RASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS-KRLEQLEKENKSLEQE 823
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEennvkignLEKENKTLFKEINVYKESCVRLkELEKENKELVKRATIDIKT 903
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELE--------AAALEERLKEARLLLLIAAALL-ALLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkeRLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARL 983
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGKEAEELQAL-----PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 984 EESTNYNQQLRhelktvkknyeaLKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQ 1063
Cdd:COG4717 354 REAEELEEELQ------------LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1907079586 1064 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1107
Cdd:COG4717 422 LEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-988 |
4.84e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 4.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 746 ASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvykescVRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-----------QYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeqSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL----ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAA 237
|
....
gi 1907079586 985 ESTN 988
Cdd:COG4942 238 AAAE 241
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
5.04e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.89 E-value: 5.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 559 ENEHLNQTVSSLRQRSQISAEARVKDIEK-ENKILHESIKETCGKLSK----IEFEK-RQ--MKKELELYKEKGERAEEL 630
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERrrklEEAEKaRQaeMDRQAAIYAEQERMAMER 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 631 ENELNHLGKEN---ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:pfam17380 347 ERELERIRQEErkrELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 708 RSVESLKcasmrmaqlQLENKELESEKEQlrkglELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESElq 787
Cdd:pfam17380 427 AEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE-- 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 788 dlEMENQTLQKSLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK--E 865
Cdd:pfam17380 491 --EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKatE 563
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1907079586 866 NKTLFKEINVYKESCVRLKELEKENKELvkRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 564 ERSRLEAMEREREMMRQIVESEKARAEY--EATTPITTIKPIYRPRISE 610
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1148 |
6.56e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 6.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRyKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRHE 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-AALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 997 LKTVKKNY-EALKQRQDEERMVQSSIPVSGEDdkwgreSQEATRellkvkdRLIEVERNNATLQAEKQALKTQLKQLETQ 1075
Cdd:COG4942 99 LEAQKEELaELLRALYRLGRQPPLALLLSPED------FLDAVR-------RLQYLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 1076 NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
973-1183 |
7.01e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 7.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 973 EEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSsipVSGEDDKWgresQEATRELLKVKDRLIEVE 1052
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE---YSWDEIDV----ASAEREIAELEAELERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1053 RNNATLQAekqaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQ 1132
Cdd:COG4913 682 ASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAA 757
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 1133 SSLENENESIMKE-REDLKSLYDALIKDHEKLELLHERQASEYESLISKHGT 1183
Cdd:COG4913 758 ALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFNREWPAETADLDA 809
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1202 |
9.24e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 9.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 850 -----TTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 lperlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 925 LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEK-------------IAALEARLEESTNYNQ 991
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLIltiagvlflvlglLALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 992 QLRHELKTVKKnYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRelLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1071
Cdd:COG4717 302 KEAEELQALPA-LEELEEEELEELLAALGLPPDLSPEELLELLDRIEE--LQELLREAEELEEELQLEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1072 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDL 1149
Cdd:COG4717 379 AGVEDEEELRAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL 458
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 1150 KSLYDALIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHKDLEDRY 1202
Cdd:COG4717 459 EAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
568-1010 |
1.03e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 568 SSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKK 647
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 648 ITNLKItCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSV-----ESLKCASMRMAQ 722
Cdd:COG4717 125 LQLLPL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslateEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 723 LQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQgldtENQRLQKALEnsnkkIQQLESELQDLEMENQTLQKSLEE 802
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAA----LEERLKEARL-----LLLIAAALLALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 803 LK--------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIN 874
Cdd:COG4717 275 IAgvlflvlgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 875 VYKESC--VRLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD-D 951
Cdd:COG4717 355 EAEELEeeLQLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElE 431
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 952 SRYKLLESKLEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG4717 432 EELEELEEELEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
605-1241 |
1.34e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.72 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 605 KIEFEKRQMKKELELYKEK-GERAEELENELNHLGKENELLQKKITNLKITC----EKLETLEQENSELERE----NRKF 675
Cdd:pfam05483 113 KIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCarsaEKTKKYEYEREETRQVymdlNNNI 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 676 KKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES--LKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTER 753
Cdd:pfam05483 193 EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQ 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 754 LEvsyqgldtENQRLQ-KALENSNKKIQQLESELQDLEMENQ---TLQKSLEE-LKISSKRLEQLEKENKSLEQETSQLE 828
Cdd:pfam05483 273 LE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQIATKTICQLTEEKEAQMEELNKAK 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 829 KDKKQLEKENKRLRQQAEikdTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELeKENKELVKRatiDIKTLVTLR 908
Cdd:pfam05483 345 AAHSFVVTEFEATTCSLE---ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF-KNNKEVELE---ELKKILAED 417
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 909 EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQ------STDDSRYKLLESKLESTLKKSLEIKEEKIAALEAR 982
Cdd:pfam05483 418 EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 983 LEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLK-----VKDRLIEVERNNAT 1057
Cdd:pfam05483 498 LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIqkgdeVKCKLDKSEENARS 577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1058 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1137
Cdd:pfam05483 578 IEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGS---AENKQLNAYEIKVNKLELELASAKQKFEE 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1138 ENESIMKEREDLKSLYDALIKDHEKLEL-------------------------LHERQASEYESLISKHGTLKSAHKNLE 1192
Cdd:pfam05483 655 IIDNYQKEIEDKKISEEKLLEEVEKAKAiadeavklqkeidkrcqhkiaemvaLMEKHKHQYDKIIEERDSELGLYKNKE 734
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907079586 1193 VEHK--------DLEDRYNQLLKQKGQLEdlekMIKTEQEKMLLESKNHEVVASEYK 1241
Cdd:pfam05483 735 QEQSsakaaleiELSNIKAELLSLKKQLE----IEKEEKEKLKMEAKENTAILKDKK 787
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
663-1016 |
1.51e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 49.52 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 663 QENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLelrRSVESLKCASMR------MAQLQLENKELESEKEQ 736
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSL---RTVMELPQKSTSsdddhnRASMQRDEAIAAIDNEQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 737 LRKglelmrasfKKTERLEVSYQGLDtenqrLQKALENSNKKIQQLE----SELQDLE---MENQTLQKsleELKISSKR 809
Cdd:PLN02939 116 QTN---------SKDGEQLSDFQLED-----LVGMIQNAEKNILLLNqarlQALEDLEkilTEKEALQG---KINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKE---- 885
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAEteer 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 886 ---LEKEN-------KELVKR---ATIDIKTLVTLREDLVSEKLKTQQMNndLEKLTHELEKIGLnkerLLHDEQSTDDS 952
Cdd:PLN02939 259 vfkLEKERslldaslRELESKfivAQEDVSKLSPLQYDCWWEKVENLQDL--LDRATNQVEKAAL----VLDQNQDLRDK 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 953 RYKLLESKLESTLKK----SLEIKEEKIAALEARL----EESTNYNQQLRHELKTVKKNYEALKQRQDEERM 1016
Cdd:PLN02939 333 VDKLEASLKEANVSKfssyKVELLQQKLKLLEERLqasdHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSL 404
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
1.65e-05 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 47.31 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 716 ASMRMAQLQLENKELESEKEQLRKGLELMRASFKKterLEVSYQGLDTENQRLQKALEnsnkKIQQLESELQDLEMENQT 795
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQEQLAELRQENQE---LKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRE 136
|
90 100 110
....*....|....*....|....*....|.
gi 1907079586 796 LQKSLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 137 LREELAELK---QENEALEAENERLQENEQR 164
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
2.40e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 427 LHLGWELEQISRTSELAEApqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 507 VEILENEIIQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-894 |
3.12e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 47.75 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 508 EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 582 VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-----LYKEKgERAEELENELNHLGKENELLQKKITNLKitcE 656
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEalerqLAAET-EQNRALEEENKALREEAQAAEKALQRAE---G 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 657 KLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESlKCASMR------MAQLQLENKEL 730
Cdd:pfam19220 161 ELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVEAH 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 731 ESEKEQLRKGLELMRASFKKTERLevsyqgldtenqrlqkalensnkkIQQLESELQDLEMENQTLQKSLEELKIS---- 806
Cdd:pfam19220 240 RAERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErdtl 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScvrlkeL 886
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAA------L 369
|
....*...
gi 1907079586 887 EKENKELV 894
Cdd:pfam19220 370 EQANRRLK 377
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
359-838 |
3.16e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 48.23 E-value: 3.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 359 TKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKqsmdeslHLGWELEQISR 438
Cdd:COG4717 65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ-------LLPLYQELEAL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 439 TSELAEAPQK--SLGHEVNELTSskllkLEMENQSLTKTVEELRSTADSAAGSTSkiLKVEKENQRLNKKVEILENEIIQ 516
Cdd:COG4717 138 EAELAELPERleELEERLEELRE-----LEEELEELEAELAELQEELEELLEQLS--LATEEELQDLAEELEELQQRLAE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETlrenserqikilEQENEHLNQTVSSLRQRSQISA-EARVKDIEKENKILHES 595
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEA------------AALEERLKEARLLLLIAAALLAlLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 596 IKETCGKLSKIEFEKRQMKKELE--------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSE 667
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGkeaeelqaLPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 668 LEREnrkfkktldsfknltFQLESLEKENSQLDEENLElrRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAS 747
Cdd:COG4717 359 LEEE---------------LQLEELEQEIAALLAEAGV--EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 748 FKKT--ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEmENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:COG4717 422 LEALdeEELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALE 500
|
490
....*....|...
gi 1907079586 826 QLEKDKKQLEKEN 838
Cdd:COG4717 501 LLEEAREEYREER 513
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
4.93e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.13 E-value: 4.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 657 KLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 737 LRKGLELMRASFKKTERLEV-----SYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLE 811
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---ALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
255-379 |
5.12e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 5.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 255 DAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENM------NLLSDARSARMYRDELDALREKAVRVDKLESE 328
Cdd:COG4913 607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalqrlaEYSWDEIDVASAEREIAELEAELERLDASSDD 686
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 329 LSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Cdd:COG4913 687 LAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1046-1249 |
5.58e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1126 AQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQL 1205
Cdd:TIGR02168 312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 1206 LKQKG-----------QLEDLEKMI-KTEQEKMLLESKNHEVVASEYKKLCGENDR 1249
Cdd:TIGR02168 392 ELQIAslnneierleaRLERLEDRReRLQQEIEELLKKLEEAELKELQAELEELEE 447
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
491-695 |
6.37e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.32 E-value: 6.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 491 SKILKVEKENQRLNKKVEILENEI-IQEK----QSLQNCQNLSK--DLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Cdd:PHA02562 174 DKIRELNQQIQTLDMKIDHIQQQIkTYNKnieeQRKKNGENIARkqNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 564 NQTVSSLRQrSQISAEARVKDIEKENKILHE---------SIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENEL 634
Cdd:PHA02562 254 SAALNKLNT-AAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEF 332
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 635 NHlgkenelLQKKITNLKitcEKLETLEQENSELERENRKFKKTL----DSFKNLTFQLESLEKE 695
Cdd:PHA02562 333 NE-------QSKKLLELK---NKISTNKQSLITLVDKAKKVKAAIeelqAEFVDNAEELAKLQDE 387
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1033-1211 |
7.22e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 7.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1033 ESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLQVENS 1112
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE---IEERREELGERARALYRSGG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1113 T-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:COG3883 101 SvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1907079586 1171 ASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQ 1211
Cdd:COG3883 181 EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
512-858 |
8.27e-05 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 46.99 E-value: 8.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 512 NEIIQEKQSL-QNCQNLSKD---LMKEKAQLEKTIETLRENSER--------------------QIKILEQENEHLNQTV 567
Cdd:pfam05622 3 SEAQEEKDELaQRCHELDQQvslLQEEKNSLQQENKKLQERLDQlesgddsgtpggkkylllqkQLEQLQEENFRLETAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 568 SSLRQRSQIsaearvkdIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELE----------NELNHL 637
Cdd:pfam05622 83 DDYRIKCEE--------LEKEVLELQHRNEE----LTSLAEEAQALKDEMDILRESSDKVKKLEatvetykkklEDLGDL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 638 GKENELLQKKITN-LKITCE-------------KLETLEQENSELER----ENRKFKKTLDSFKNLTFQLESLEKENSQL 699
Cdd:pfam05622 151 RRQVKLLEERNAEyMQRTLQleeelkkanalrgQLETYKRQVQELHGklseESKKADKLEFEYKKLEEKLEALQKEKERL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 700 DEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRK-GLELMRASFKKT-ERLEVSYQGLD-----TENQR---LQ 769
Cdd:pfam05622 231 IIERDTLRETNEELRCAQLQQAELSQADALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRlgqegSYRERlteLQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 770 KALENSNKKIQQLESEL-----QDLEMENQT--LQKSLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam05622 311 QLLEDANRRKNELETQNrlanqRILELQQQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELE 390
|
410 420
....*....|....*....|
gi 1907079586 839 KRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 391 PKQDSNLAQKIDELQEALRK 410
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
719-854 |
8.72e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTenqrlqkaLENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE--------YSWDEIDVASAEREIAELEAELERLDA 682
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907079586 799 SLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:COG4913 683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
8.74e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 46.01 E-value: 8.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLFKEINVYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 1907079586 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
9.09e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 9.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 577 SAEARVKDIEKE-NKILHESIKE--TCGKLSKIEFEKRQMKKELELYKEKGERaeelENELNHLgkENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEaeAIKKEALLEAKEEIHKLRNEFEKELRER----RNELQKL--EKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1907079586 654 tcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
641-940 |
9.34e-05 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 47.14 E-value: 9.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 641 NELLQKKITNLKIT----CEKLETLEQENSELERENRKFKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRRSVE 711
Cdd:PRK00448 4 QEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSIEVE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 712 SLKCasmrmaQLQLENKELESEKEQLRKGLELMRASFKKTE------RLEVSYQGlDTENQRL-QKALENSNKKIQQLES 784
Cdd:PRK00448 84 NITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEKFGF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 785 ELqdLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KDTTL 852
Cdd:PRK00448 157 GI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKEINE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 853 EENNVKI-GNL------EKENKTLFKEINV--YKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQQMN 922
Cdd:PRK00448 235 EERRVVVeGYVfkveikELKSGRHILTFKItdYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDLVMN 313
|
330
....*....|....*....
gi 1907079586 923 -NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 314 aQDINEIKHPERKDTAEEE 332
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
455-856 |
1.01e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.97 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 455 NELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQE--KQSLQNCQNLSKDLM 532
Cdd:TIGR01612 1353 NILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKdiDECIKKIKELKNHIL 1432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 533 KEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQ 612
Cdd:TIGR01612 1433 SEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKA 1508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 613 MKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsFKNLTFQLESL 692
Cdd:TIGR01612 1509 IEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKEKFRIEDD 1584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 693 EKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKglelmrasfkkterlEVSYQGLDTENQRLQKAL 772
Cdd:TIGR01612 1585 AAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEK---------------KISSFSIDSQDTELKENG 1649
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 773 ENSNkkiqqleselqdlemenqTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQlEKENKRLRQQAEIKDTTL 852
Cdd:TIGR01612 1650 DNLN------------------SLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQ-HKKNYEIGIIEKIKEIAI 1710
|
....
gi 1907079586 853 EENN 856
Cdd:TIGR01612 1711 ANKE 1714
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
656-846 |
1.22e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 656 EKLETLEQENSELEREnrkfkktldsFKNLTFQLESLEKENSQLDEENLELRRsVESLKCASMRMAQLQLENKELESEKE 735
Cdd:COG4913 610 AKLAALEAELAELEEE----------LAEAEERLEALEAELDALQERREALQR-LAEYSWDEIDVASAEREIAELEAELE 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 736 QLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS--KRLEQL 813
Cdd:COG4913 679 RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAA 758
|
170 180 190
....*....|....*....|....*....|...
gi 1907079586 814 EKENkSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG4913 759 LGDA-VERELRENLEERIDALRARLNRAEEELE 790
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
538-679 |
1.25e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 46.39 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 538 LEKTIETLRENSERQIkilEQENEHLNQTVSSLRQRsqISA-EARVKDIEKENKILHESIKEtcgKLSKIEfekrQMKKE 616
Cdd:COG2433 382 LEELIEKELPEEEPEA---EREKEHEERELTEEEEE--IRRlEEQVERLEAEVEELEAELEE---KDERIE----RLERE 449
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 617 LELYKEKGERAEELENELNHLGKENELLQKkitnlkitceKLETLEQENSELERENRKFKKTL 679
Cdd:COG2433 450 LSEARSEERREIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKELW 502
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-840 |
1.35e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.37 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 326 ESElsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRkki 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIR--- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 406 eelmeenmtlemaqkqsmdeslhlgwelEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:pfam12128 404 ----------------------------EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQ 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 486 AAGSTSKILKVEKENQRLNKKVEILEneiiqekqslqncqnlskdlmkekaQLEKTIETLRENSERQIKILEQENEHLNQ 565
Cdd:pfam12128 456 ATATPELLLQLENFDERIERAREEQE-------------------------AANAEVERLQSELRQARKRRDQASEALRQ 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 566 TVSSLRQRSQISAEARVKDIEKENKILH------ESIKETCGKLSKIEFEKRQmkkelelykekgeraeELENELNHLGK 639
Cdd:pfam12128 511 ASRRLEERQSALDELELQLFPQAGTLLHflrkeaPDWEQSIGKVISPELLHRT----------------DLDPEVWDGSV 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 640 ENELlqkKITNLKITCEKLETLE--QENSELERENRKFKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRSVESLKCA 716
Cdd:pfam12128 575 GGEL---NLYGVKLDLKRIDVPEwaASEEELRERLDKAEEALQSAREKQAAAEEqLVQANGELEKASREETFARTALKNA 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 717 SMRMAQLqleNKELESEKEQLRKGLElMRASFKKTERLEVSYQgldtenqrlQKALENsnkKIQQLESELQDLEMENQTl 796
Cdd:pfam12128 652 RLDLRRL---FDEKQSEKDKKNKALA-ERKDSANERLNSLEAQ---------LKQLDK---KHQAWLEEQKEQKREART- 714
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1907079586 797 QKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Cdd:pfam12128 715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKR 758
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
656-859 |
1.41e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.16 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 656 EKLETLEQENSELERENRKFKKTLDSF------KNLTFQLESLEKENSQLDEENLELRRSVESLKcASMRMAQLQLEN-- 727
Cdd:COG3206 182 EQLPELRKELEEAEAALEEFRQKNGLVdlseeaKLLLQQLSELESQLAEARAELAEAEARLAALR-AQLGSGPDALPEll 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 728 -----KELESEKEQLRKGLELMRASFKKTERlevSYQGLDTENQRLQKALENSNKKI-QQLESELQDLEMENQTLQKSLE 801
Cdd:COG3206 261 qspviQQLRAQLAELEAELAELSARYTPNHP---DVIALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLA 337
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907079586 802 ELKISSKRLEQLEKENKSLEQEtsqLEKDKKQLEKENKRLrQQAEIkDTTLEENNVKI 859
Cdd:COG3206 338 QLEARLAELPELEAELRRLERE---VEVARELYESLLQRL-EEARL-AEALTVGNVRV 390
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
482-1063 |
1.42e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 46.36 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 482 TADSAAGSTSKILKVEKenqRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqene 561
Cdd:PTZ00440 430 IADYALYSNLEIIEIKK---KYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE---- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 562 hLNQTVSSLRQRSQISAEaRVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKEN 641
Cdd:PTZ00440 503 -LLQIINSIKEKNNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENV 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 642 ELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsfknltfqleslEKENSQLDEENLELRRSVESLKCASMRMA 721
Cdd:PTZ00440 581 DHIKDIISLNDEIDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELS 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 722 QLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyqgldtenqrlQKALENSNKKIQQLESELQDL-EMENQTLQKSL 800
Cdd:PTZ00440 646 HFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQL 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 801 EELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLFKEINVYKES 879
Cdd:PTZ00440 713 NNIEQDiSNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDT 788
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEqstDDSRYKLLES 959
Cdd:PTZ00440 789 ILNKENKISNDINILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDENLNLKE---LEKEFNENNQ 863
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 960 KLESTLKKSLEI--KEEKIAALEARLEESTNYNQQLRHelktVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESqEA 1037
Cdd:PTZ00440 864 IVDNIIKDIENMnkNINIIKTLNIAINRSNSNKQLVEH----LLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLN-NL 938
|
570 580
....*....|....*....|....*.
gi 1907079586 1038 TRELLKVKDRLIEVERNNATLQAEKQ 1063
Cdd:PTZ00440 939 NKEKEKIEKQLSDTKINNLKMQIEKT 964
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-695 |
1.45e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.50 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 183 QEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 263 LRQELEEKTEQLLD----CKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKERLHD 338
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 339 IEfykarveelKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENlQLKAKLHDMEMERDMDRKKIEELMEENMTLEMA 418
Cdd:TIGR00618 544 EE---------DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN-RSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 419 QKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSskLLKLEMENQSLTKTVEELRSTAdsaagstskilkvek 498
Cdd:TIGR00618 614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLT--LTQERVREHALSIRVLPKELLA--------------- 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 499 ENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:TIGR00618 677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 579 EARVKDIEKENK---ILHESIKETCGKLSKIEFEKRQMKKELELYKE-KGERAEELENELNHLGKENELLQKKITNLKIT 654
Cdd:TIGR00618 757 KARTEAHFNNNEevtAALQTGAELSHLAAEIQFFNRLREEDTHLLKTlEAEIGQEIPSDEDILNLQCETLVQEEEQFLSR 836
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1907079586 655 CEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:TIGR00618 837 LEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
621-803 |
1.66e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.06 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 621 KEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSElERENRKFKKTLDSFKNltfQLESLEKENSQLD 700
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD-EIDVASAEREIAELEA---ELERLDASSDDLA 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 701 EENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKI- 779
Cdd:COG4913 689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELr 768
|
170 180
....*....|....*....|....
gi 1907079586 780 QQLESELQDLEMENQTLQKSLEEL 803
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERA 792
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
589-837 |
1.66e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.78 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 589 NKILHESIKETCGKLSKIEFEKRQMKKELELYKEkgeraeeLENELNHLGKEN-ELLQKKITNLKitcEKLETLEQENSE 667
Cdd:PHA02562 169 DKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNK-------NIEEQRKKNGENiARKQNKYDELV---EEAKTIKAEIEE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 668 LERE----NRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCasmrMAQLQLENKELESEKEQLRKGlel 743
Cdd:PHA02562 239 LTDEllnlVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----TQQISEGPDRITKIKDKLKEL--- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 744 mrasfkkTERLEVSYQGLDTENQRLQKALENSnKKIQQLESelqDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQE 823
Cdd:PHA02562 312 -------QHSLEKLDTAIDELEEIMDEFNEQS-KKLLELKN---KISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE 380
|
250
....*....|....
gi 1907079586 824 TSQLEKDKKQLEKE 837
Cdd:PHA02562 381 LAKLQDELDKIVKT 394
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
536-947 |
1.78e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 536 AQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRsqisaEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKK 615
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK-----EEEYAELQEELEELEEELEELEAELEELREELEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 616 ELELYKEKGERaEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERE-----NRKFKKTLDSFKNLTFQLE 690
Cdd:COG4717 124 LLQLLPLYQEL-EALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEEleellEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 691 SLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR-------------KGLELMRASFKKTERLEVS 757
Cdd:COG4717 203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallgLGGSLLSLILTIAGVLFLV 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 758 YQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:COG4717 283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 838 NKRLRQQAEIK------DTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVkratiDIKTLVTLREDL 911
Cdd:COG4717 363 LQLEELEQEIAallaeaGVEDEEELRAALEQAEEYQELKEELEELEE---QLEELLGELEELL-----EALDEEELEEEL 434
|
410 420 430
....*....|....*....|....*....|....*.
gi 1907079586 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQ 947
Cdd:COG4717 435 EELEEELEELEEELEELREELAELEAELEQLEEDGE 470
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-652 |
1.94e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.88 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELMEENmtlEMAQKQSMD 424
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKREL---ERIRQEEIA 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 425 ESLHLGWELEQISRTSElaeAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRln 504
Cdd:pfam17380 372 MEISRMRELERLQMERQ---QKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAR-- 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 505 kKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvsslRQRSQISAEARVKD 584
Cdd:pfam17380 447 -EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--------RKQAMIEEERKRKL 517
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 585 IEKENKILHESIKETcgKLSKIEFEKRQMKKELELYK---EKGERAEELENELNHLGKENELLQKKITNLK 652
Cdd:pfam17380 518 LEKEMEERQKAIYEE--ERRREAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
2.01e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 326 E-----SELSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 1907079586 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1073 |
2.10e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.28 E-value: 2.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLemeNQTLQKSLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLK--ELEKENK 891
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSeaEAEQALD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI 971
Cdd:COG4372 187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 972 KEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEV 1051
Cdd:COG4372 267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
330 340
....*....|....*....|..
gi 1907079586 1052 ERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG4372 347 LVGLLDNDVLELLSKGAEAGVA 368
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
2.17e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 45.52 E-value: 2.17e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
957-1120 |
2.35e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 957 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDE--ERMVQSSIPVSGED------- 1027
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRALYRSGGSVSYLDvllgses 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1028 --------DKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG3883 114 fsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAA 193
|
170 180
....*....|....*....|.
gi 1907079586 1100 LQTQNAKLQVENSTLNSQSTS 1120
Cdd:COG3883 194 AEAQLAELEAELAAAEAAAAA 214
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-383 |
2.42e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.46 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmNLLSDARSARmYRDELDALREkavrvdKLESELSRYKERLHDIEf 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEE------ELEALKARWEAEKELIE- 471
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1907079586 342 ykaRVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:COG0542 472 ---EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE 510
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
548-822 |
2.53e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 548 NSERQIKILEQENEHLNQTVSslrqrsqiSAEARVKDIEKENKILHEsIKETCGKLSKIEFEkrqmkkELELyKEKGERA 627
Cdd:COG4913 607 DNRAKLAALEAELAELEEELA--------EAEERLEALEAELDALQE-RREALQRLAEYSWD------EIDV-ASAEREI 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 628 EELENELNHLGKEN---ELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSF----KNLTFQLESLEKENSQLD 700
Cdd:COG4913 671 AELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQAeeelDELQDRLEAAEDLARLEL 747
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 701 EENLELRRSVESLKCASMRM-AQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTEN----QRLQKALENS 775
Cdd:COG4913 748 RALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESlpeyLALLDRLEED 827
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 776 N-----KKIQQL--ESELQDLEMENQTLQKSLEELKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 828 GlpeyeERFKELlnENSIEFVADLLSKLRRAIREIK------ERIDPLNDSLKR 875
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
979-1213 |
2.54e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 979 LEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwgreSQEATRELLKVKDRLIEVERNNATL 1058
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEE-------AKLLLQQLSELESQLAEARAELAEA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1059 QAEKQALKTQLKQLETQNNNLQaqilalqrQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Cdd:COG3206 239 EARLAALRAQLGSGPDALPELL--------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 1139 NESIMkerEDLKSLYDALIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLE 1213
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
658-1207 |
2.69e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 45.20 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 658 LETLEQENSELERE----NRKFKKTLDSFKnlTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESE 733
Cdd:pfam10174 5 LRDLQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 734 keqlrkglelMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQ- 812
Cdd:pfam10174 83 ----------LRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQt 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 813 LEKENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvyKESCVRLKELEKEN 890
Cdd:pfam10174 153 LGARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPDP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 891 KElvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD--------SRYKLLESKLE 962
Cdd:pfam10174 226 AK--------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevykSHSKFMKNKID 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 963 sTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeerMVQSsipvsgEDDKWGRESQEATRELL 1042
Cdd:pfam10174 293 -QLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA---ILQT------EVDALRLRLEEKESFLN 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1043 KVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLM 1122
Cdd:pfam10174 363 KKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLE 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1123 NQNA------QLLIQQSSLEN-----ENESIMKEREDLKSLYDALIKDHEKLEL----LHERQASEYESLISKHGTLKSA 1187
Cdd:pfam10174 443 EALSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKSL 522
|
570 580
....*....|....*....|
gi 1907079586 1188 HKNLEVEHKDLEDRYNQLLK 1207
Cdd:pfam10174 523 EIAVEQKKEECSKLENQLKK 542
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-642 |
2.80e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 45.28 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 321 RVDKLESELSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSskllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 478 ELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIETLRENSERQIKIL 556
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVEnLQDLLDRATNQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 557 EQeNEHLNQTVSSLRQRsqiSAEARVKDIEKEN-KILHESIKETCGKLSKIEFEkrqMKKELELYKEKgerAEELENELN 635
Cdd:PLN02939 324 DQ-NQDLRDKVDKLEAS---LKEANVSKFSSYKvELLQQKLKLLEERLQASDHE---IHSYIQLYQES---IKEFQDTLS 393
|
....*..
gi 1907079586 636 HLGKENE 642
Cdd:PLN02939 394 KLKEESK 400
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-399 |
2.83e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 332 YKERLHDIEF-YKARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG4913 364 LEALLAALGLpLPASAEEFAALRAEAAALLEALEEELEALE---EALAEAEAALRDLRRELRELEAEIA 429
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-837 |
2.91e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.40 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESELSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSS------KLLKLEMENQSLT 473
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQisqlkkELTNSESENSEKQ 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 474 KTVEElrstadsaagSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQI 553
Cdd:TIGR04523 363 RELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKEI 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 554 KILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELelyKEKGERAEELENE 633
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQDS-VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLNEE 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 634 LNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSfKNLTFQLESLEKENSQLDEENLELRRSVESL 713
Cdd:TIGR04523 505 KKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQKSL 580
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 714 KCASmrmAQLQLENKELESEKEQLRKGLELMRASF----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ-- 787
Cdd:TIGR04523 581 KKKQ---EEKQELIDQKEKEKKDLIKEIEEKEKKIssleKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKei 657
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 788 ----------------DLEMENQTLQKSLEELKISSKR-----------------LEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:TIGR04523 658 rnkwpeiikkikesktKIDDIIELMKDWLKELSLHYKKyitrmirikdlpkleekYKEIEKELKKLDEFSKELENIIKNF 737
|
...
gi 1907079586 835 EKE 837
Cdd:TIGR04523 738 NKK 740
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
622-714 |
3.21e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.85 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLET-LEQENSELERENRKFKKtldsFKNLTFQLESLEKENSQLD 700
Cdd:COG2433 410 EEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLEReLSEARSEERREIRKDRE----ISRLDREIERLERELEEER 485
|
90
....*....|....
gi 1907079586 701 EENLELRRSVESLK 714
Cdd:COG2433 486 ERIEELKRKLERLK 499
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-869 |
3.49e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.07 E-value: 3.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 779 IQQLESELQDLEMENQTLQKslEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|.
gi 1907079586 859 IGNLEKENKTL 869
Cdd:COG0542 487 IPELEKELAEL 497
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
3.70e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.92 E-value: 3.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 729 ELESEKEQLRKGLELMRASFKKT-----ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 867 ------KTLFKEINVYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
719-865 |
4.31e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 4.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTE----RLEVSYQGLDTENQRLQKALEN--SNKKIQQLESELQDLEME 792
Cdd:COG1579 25 RLKELPAELAELEDELAALEARLEAAKTELEDLEkeikRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRR 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 793 NQTLQKSLEELkisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:COG1579 105 ISDLEDEILEL------MERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1082 |
5.53e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 5.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYK 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 956 LLESKLESTLKKSLEIKEEKIAALEARLEEStnynQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgedDKWGRESQ 1035
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLS--------LATEEELQ 195
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1907079586 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Cdd:COG4717 196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
495-852 |
5.58e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 5.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 495 KVEKENQRLN----KKVEILENEII--QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERqikiLEQENEhlnqtVS 568
Cdd:PRK04863 301 QLAAEQYRLVemarELAELNEAESDleQDYQAASDHLNLVQTALRQQEKIERYQADLEELEER----LEEQNE-----VV 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 569 SLRQRSQISAEARVKDIEkenkilhESIKETCGKLSK-----IEFEKR--QMKKELELYkekgERAEELeNELNHLGKEN 641
Cdd:PRK04863 372 EEADEQQEENEARAEAAE-------EEVDELKSQLADyqqalDVQQTRaiQYQQAVQAL----ERAKQL-CGLPDLTADN 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 642 --ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESlekenSQLDEENLELRRSVESLKCASMR 719
Cdd:PRK04863 440 aeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSR-----SEAWDVARELLRRLREQRHLAEQ 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 720 MAQLQLENKELESEKEQLRKgLELMRASFKKteRLEVSYQG---LDTENQRLQKALENSN--------------KKIQQL 782
Cdd:PRK04863 515 LQQLRMRLSELEQRLRQQQR-AERLLAEFCK--RLGKNLDDedeLEQLQEELEARLESLSesvsearerrmalrQQLEQL 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 783 ESELQDLEM---ENQTLQKSLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:PRK04863 592 QARIQRLAArapAWLAAQDALARLReqsgeefedsqdVTEYMQQLLERE-RELTVERDELAARKQALDEEIERLSQPGGS 670
|
....*
gi 1907079586 848 KDTTL 852
Cdd:PRK04863 671 EDPRL 675
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
716-878 |
5.95e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 5.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 716 ASMRMAQLQLENKELESEKEQLRKglelmrasfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT 795
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQA----------ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 796 LQKSLEEL----------------------------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:COG3883 84 RREELGERaralyrsggsvsyldvllgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1907079586 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKE 878
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA 203
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-713 |
6.14e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 6.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 498 KENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKILEQENEHLNQTVSSLRQRsqis 577
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKE---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 578 AEARVKDIEKENKILHESIKE--TCGKLSKIEF-----EKRQMKKELELYK----EKGERAEELENELNHLGKENELLQK 646
Cdd:COG4942 92 IAELRAELEAQKEELAELLRAlyRLGRQPPLALllspeDFLDAVRRLQYLKylapARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907079586 647 KITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESL 713
Cdd:COG4942 172 ERAELE---ALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARL 232
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1089 |
6.63e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 43.40 E-value: 6.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 792 ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 872 EINVYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 951 DSRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQ------------RQDEE 1014
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 1015 RMVQSSIPVSGEDDKWGRESQEATRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
405-690 |
7.62e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.76 E-value: 7.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 405 IEELMEENMtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkSLGHEVNELTSSKLLKLEMENQSLtktvEELRSTAD 484
Cdd:PRK05771 22 LEALHELGV-VHIEDLKEELSNERLRKLRSLLTKLSEALD----KLRSYLPKLNPLREEKKKVSVKSL----EELIKDVE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 485 SAAGstskilKVEKENQRLNKKVEILENEI---IQEKQSLQNCQNLSKDLmkEKAQLEKTIE----TLRENSERQIKILE 557
Cdd:PRK05771 93 EELE------KIEKEIKELEEEISELENEIkelEQEIERLEPWGNFDLDL--SLLLGFKYVSvfvgTVPEDKLEELKLES 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 558 QENEHLnqTVSSLRQRSQISAEARVKDIEKENKILHesiketcgKLSKIEFEKRQMKKELELYKEKGERAEELENELNHL 637
Cdd:PRK05771 165 DVENVE--YISTDKGYVYVVVVVLKELSDEVEEELK--------KLGFERLELEEEGTPSELIREIKEELEEIEKERESL 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 638 GKE-NELLQKKITNLKITCEKLETLEQENSELErenrKFKKTldsfkNLTFQLE 690
Cdd:PRK05771 235 LEElKELAKKYLEELLALYEYLEIELERAEALS----KFLKT-----DKTFAIE 279
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
882-1089 |
9.81e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 9.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 882 RLKELEKENKELvKRATIDIKTLVTLREDLVSEK--LKTQQMNNDLEKLTHELEKIGLNKERLlhdeqstdDSRYKLLES 959
Cdd:COG4913 253 LLEPIRELAERY-AAARERLAELEYLRAALRLWFaqRRLELLEAELEELRAELARLEAELERL--------EARLDALRE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 960 KLESTLKKSLEIKEEKIAALEARLEestnynqQLRHELKTVKKNYEALKQRQdeeRMVQSSIPVSGED-----DKWGRES 1034
Cdd:COG4913 324 ELDELEAQIRGNGGDRLEQLEREIE-------RLERELEERERRRARLEALL---AALGLPLPASAEEfaalrAEAAALL 393
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 1035 QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:COG4913 394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
960-1170 |
1.01e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.50 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 960 KLESTLKKSLEIKEEKIAALEARLEeSTNYNQQLrheLKTVKKNYEA---LKQRQDEERMVQSSIpvsgedDKWGRESQE 1036
Cdd:PRK10929 79 KLSAELRQQLNNERDEPRSVPPNMS-TDALEQEI---LQVSSQLLEKsrqAQQEQDRAREISDSL------SQLPQQQTE 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1037 ATRELLKVKDRL--------IEVERNNATLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqt 1102
Cdd:PRK10929 149 ARRQLNEIERRLqtlgtpntPLAQAQLTALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL-- 220
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907079586 1103 qNAKLQVENSTLNSQStslmNQNAQLLIQQSSLENEN-----ESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:PRK10929 221 -DAYLQALRNQLNSQR----QREAERALESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
1.09e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 571 RQRSQISAE-ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE-----LELYKEKGERAEELENELNHLGKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADEtladrLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 645 QKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrsVESLKcasmrmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 724 qlenKELESEKEQLRkglelmrasfkktERLEVSYQGLDTENQRLQK---ALENSNKKIQQLESELQDL------EMENQ 794
Cdd:COG3096 994 ----EQAEEARREAR-------------EQLRQAQAQYSQYNQVLASlksSRDAKQQTLQELEQELEELgvqadaEAEER 1056
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 795 TLQKSLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1057 ARIRRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-872 |
1.10e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 42.41 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 768 LQKALENSNKKIQQLESELQDLEMENQTLQksleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEi 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELE----------SELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFE- 201
|
90 100
....*....|....*....|....*
gi 1907079586 848 kdTTLEENNVKIGNLEKENKTLFKE 872
Cdd:COG4026 202 --ELLKKRLLEVFSLEELWKELFPE 224
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-671 |
1.13e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 464 KLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-L 619
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEaL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 620 YKEKGERAEELENELNhlgKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:COG4942 180 LAELEEERAALEALKA---ERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-573 |
1.31e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.41 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 320 VRVDKLEselsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 480 RSTAD----SAAGSTSKILKVEKENQR-LNKKVEILENEIIQEKQSLQNCQNLSKdLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGevsrSEAWDVARELLRRLREQRhLAEQLQQLRMRLSELEQRLRQQQRAER-LLAEFCKRLGKNLDDEDELEQLQE 561
|
330
....*....|....*....
gi 1907079586 555 ILEQENEHLNQTVSSLRQR 573
Cdd:PRK04863 562 ELEARLESLSESVSEARER 580
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
1.33e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 41.07 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 719 RMAQLQLENKELESEKEQLRKGLELMRASfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 799 SLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKenktlfkeinvyke 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQDLQDELVALQLQLNMAEE-------------- 148
|
170
....*....|....*...
gi 1907079586 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
689-1073 |
1.39e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.96 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 689 LESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRL 768
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWE---RQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE---LSEEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:pfam07888 121 LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEEELRSLSKEFQEL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Cdd:pfam07888 198 RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 929 THELEKIGLNkerllhdeqsTDDSRYKLLE-----SKLESTLKKSLEIKEEKIAALEARLEestnynqqlrhelktvkkn 1003
Cdd:pfam07888 278 RLQAAQLTLQ----------LADASLALREgrarwAQERETLQQSAEADKDRIEKLSAELQ------------------- 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 1004 yeALKQRQDEERM--VQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:pfam07888 329 --RLEERLQEERMerEKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
|
|
| ATG14 |
pfam10186 |
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ... |
715-851 |
1.55e-03 |
|
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.
Pssm-ID: 462986 [Multi-domain] Cd Length: 347 Bit Score: 42.44 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 715 CASMRMAQLQLENKELESEKEQLRKglelmrasfKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQ 794
Cdd:pfam10186 16 CARNRLYELRVDLARLLSEKDSLKK---------KVEEALE-----GKEEGEQLEDNIGNKKLKLRLLKSEVAISNERLN 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 795 TLQKSLEELK--ISSKRlEQLEKENKSLEQETSQLEKDKKQLekENKRLRQQAEIKDTT 851
Cdd:pfam10186 82 EIKDKLDQLRreIAEKK-KKIEKLRSSLKQRRSDLESASYQL--EERRASQLAKLQNSI 137
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
678-894 |
1.72e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.98 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERL 754
Cdd:PRK11281 71 LLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTlslRQLESRLAQTLDQLQNAQNDLAEYNSQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 755 EVSYQgldTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSleelkisskRLEQLEKENKSLEQETSQlekdKKQL 834
Cdd:PRK11281 151 LVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS---------QRVLLQAEQALLNAQNDL----QRKS 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 835 EKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLFKEINVYkescvRLKELEKENKELV 894
Cdd:PRK11281 215 LEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAINSK-----RLTLSEKTVQEAQ 266
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
819-1158 |
1.74e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 42.81 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL--------EENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEN 890
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEHKRARIELEKKASALkrqldresDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 891 KELVKRATIDIKTLVTLREDLVSEK-----LKTQQMNNDLEKLTHELEKIGLNKErllHDEQSTDDSRYKLLESKLESTL 965
Cdd:pfam05557 86 EALNKKLNEKESQLADAREVISCLKnelseLRRQIQRAELELQSTNSELEELQER---LDLLKAKASEAEQLRQNLEKQQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 966 KKSLEiKEEKIAALEARLEESTNYNQqlrhELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05557 163 SSLAE-AEQRIKELEFEIQSQEQDSE----IVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1046 DRLIEVERNNATLQAEKQALKTQLKQLEtqnNNLQAQILALqRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQSWV---KLAQDTGLNL-RSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKAR 313
|
330 340 350
....*....|....*....|....*....|...
gi 1907079586 1126 AQLLIQQSSLENENESIMKEREDLKSLYDALIK 1158
Cdd:pfam05557 314 RELEQELAQYLKKIEDLNKKLKRHKALVRRLQR 346
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
1.96e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 580 ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEK------------GERAEELENELNHLGKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 648 ITNLKITCEKLE-TLEQENSELERENRKFKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRSVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
953-1176 |
2.03e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 953 RYKLLESKLESTLKKSLEIKEEkIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQssipvsgeddkwgR 1032
Cdd:COG4942 35 EIAELEKELAALKKEEKALLKQ-LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL-------------E 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1033 ESQEATRELLKVKDRLIEVERNNATLQAEK-QALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEN 1111
Cdd:COG4942 101 AQKEELAELLRALYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907079586 1112 STLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYES 1176
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
2.08e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 42.13 E-value: 2.08e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 792 ENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
664-832 |
2.17e-03 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 42.30 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 664 ENSELERENRKFKKTLDSFKNLTFQLESLEKENSQL-----DEENLELRRSVESLKCASMRMAQLQLENKElESEKEQLR 738
Cdd:PTZ00419 826 NNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCyvtakDAELIELIESAENLISTLAKIGSVSVIPPI-EEEAEVPK 904
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 739 K-GLELMRASFKKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESELQDLEMEnqtlQKSLEELK-ISSKRLEQLEKE 816
Cdd:PTZ00419 905 GcGFDVVDNKVIIYLNLDEFID-LKKELAKLEKKLAKLQKSLESYLKKISIPNYE----DKVPEDVRkLNDEKIDELNEE 979
|
170
....*....|....*.
gi 1907079586 817 NKSLEQETSQLEKDKK 832
Cdd:PTZ00419 980 IKQLEQAIEELKSLLK 995
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1036-1114 |
2.58e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 40.30 E-value: 2.58e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
752-1020 |
2.92e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 2.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSlEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSELESQLAEARAELAEAEARL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 832 KQLEKENKRLRQQAeikdtTLEENNVKIGNLEKenktlfkeinvykescvRLKELEKENKELVKRATIDIKTLVTLRedl 911
Cdd:COG3206 243 AALRAQLGSGPDAL-----PELLQSPVIQQLRA-----------------QLAELEAELAELSARYTPNHPDVIALR--- 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 912 vseklktQQMNNDLEKLTHELEKIGLNKErllhdeqstddSRYKLLESKLEStLKKSLEIKEEKIAALEARLEEStnynQ 991
Cdd:COG3206 298 -------AQIAALRAQLQQEAQRILASLE-----------AELEALQAREAS-LQAQLAQLEARLAELPELEAEL----R 354
|
250 260
....*....|....*....|....*....
gi 1907079586 992 QLRHELKTVKKNYEALKQRQDEERMVQSS 1020
Cdd:COG3206 355 RLEREVEVARELYESLLQRLEEARLAEAL 383
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
3.03e-03 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 39.60 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 1907079586 799 SLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
3.20e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 3.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 1907079586 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
765-1003 |
3.55e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 765 NQRLQKALEnsnKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL------EKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:COG4913 608 NRAKLAALE---AELAELEEELAEAEERLEALEAELDALQERREALQRLaeyswdEIDVASAEREIAELEAELERLDASS 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 839 ---KRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKRATIDIKTLVTLREDLVSEK 915
Cdd:COG4913 685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE---ELDELQDRLEAAEDLARLELRALLEERFAAALGD 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 916 LKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKL-------ESTLKKSLEIKEEKIAALEARLEES-- 986
Cdd:COG4913 762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLdadleslPEYLALLDRLEEDGLPEYEERFKELln 841
|
250 260
....*....|....*....|....
gi 1907079586 987 -------TNYNQQLRHELKTVKKN 1003
Cdd:COG4913 842 ensiefvADLLSKLRRAIREIKER 865
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
247-408 |
3.55e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR------MYRDELDALREKAV 320
Cdd:COG4913 688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleeRFAAALGDAVEREL 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 321 RvDKLESELSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDqLEGTRAR-----SDKLHELEKENLQLKAK--- 390
Cdd:COG4913 768 R-ENLEERIDALRARLNRAEeeLERAMRAFNREWPAETADLDADLES-LPEYLALldrleEDGLPEYEERFKELLNEnsi 845
|
170 180
....*....|....*....|....
gi 1907079586 391 ------LHDMEMERDMDRKKIEEL 408
Cdd:COG4913 846 efvadlLSKLRRAIREIKERIDPL 869
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
3.61e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.73 E-value: 3.61e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1907079586 784 SELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
537-698 |
4.23e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 41.59 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK----ENKILHESIKETCGKLSKIEFEKRQ 612
Cdd:COG5244 116 RLEETIEALKSTEKEEIVELRRENEELDKINLSLRERISSEEPELNKDGSKlsydELKEFVEESRVQVYDMVELVSDISE 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 613 MKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLE----TLEQENSELERENRKFKKTLDSFKNLTFQ 688
Cdd:COG5244 196 TLNRNGSIQRSSVRECERSNIHDVLFLVNGILDGVIDELNGELERLRrqlvSLMSSHGIEVEENSRLKATLEKFQSLELK 275
|
170
....*....|
gi 1907079586 689 LESLEKENSQ 698
Cdd:COG5244 276 VNTLQEELYQ 285
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
685-1132 |
5.39e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.88 E-value: 5.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 685 LTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE-NKELESEKEQLRKGLELMRASFKKT-ERLEVSYQGLD 762
Cdd:pfam05557 7 SKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDrNQELQKRIRLLEKREAEAEEALREQaELNRLKKKYLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 763 TENQRLQ-----------------KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:pfam05557 87 ALNKKLNekesqladarevisclkNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEEnNVKIGNLEKENKTLFKEINVYKEScvrlkeleKENKELVKRATIDIKTLV 905
Cdd:pfam05557 167 EAEQRIKELEFEIQSQEQDSEIVKNSKSE-LARIPELEKELERLREHNKHLNEN--------IENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 906 TLREDLVSEKLKTQQMNNDLEKLTHELEKIG--------------------LNKERLLHDEQSTDDSRYKLLEsKLESTL 965
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQSWVKLAqdtglnlrspedlsrrieqlQQREIVLKEENSSLTSSARQLE-KARREL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 966 KKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEermVQSSIPVSGEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05557 317 EQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILES---YDKELTMSNYSPQLLERIEEAEDMTQKMQ 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:pfam05557 394 AHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQ--ESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEMEL 471
|
....*..
gi 1907079586 1126 AQLLIQQ 1132
Cdd:pfam05557 472 ERRCLQG 478
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
253-782 |
5.43e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.88 E-value: 5.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsaRMYRDELDALREKAVRVDKLESELSRY 332
Cdd:pfam05557 99 LADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERL----------DLLKAKASEAEQLRQNLEKQQSSLAEA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 333 KERLHDIEF----YKARVEELKEDNQVLLETKTMlEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrkKIEEL 408
Cdd:pfam05557 169 EQRIKELEFeiqsQEQDSEIVKNSKSELARIPEL-EKELERLREHNKHLNENIENKLLLKEEVEDLKRKLE----REEKY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 409 MEENMTLEMaqkqsmdESLHLGWELEQISRTselaeAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELrstadsaag 488
Cdd:pfam05557 244 REEAATLEL-------EKEKLEQELQSWVKL-----AQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSL--------- 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 489 sTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREnserqikILEQENEHLNQTVS 568
Cdd:pfam05557 303 -TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA-------ILESYDKELTMSNY 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 569 SLRQRSQIsaearvkdiekenKILHESIKETCGKLSKIEFEKRQMKKELELYKekgERAEELENELNHLGKENELLQKKI 648
Cdd:pfam05557 375 SPQLLERI-------------EEAEDMTQKMQAHNEEMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSY 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 649 TNLKITC--EKLETLEQENSELERENRKFKKtldsfknltfqleSLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE 726
Cdd:pfam05557 439 SKEEVDSlrRKLETLELERQRLREQKNELEM-------------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQ 505
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1907079586 727 NKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDT-ENQRLQKALENSNKKIQQL 782
Cdd:pfam05557 506 LEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFkEVLDLRKELESAELKNQRL 562
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
5.62e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 5.62e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1907079586 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
5.69e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.85 E-value: 5.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 566 TVSSLRQRSQISAEARvkDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgeraEELENELNHLGKENELLQ 645
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRER----EELQREEERLVQKEEQLD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 646 KKitnlkitCEKLETLEQENSELEREnrkfkktldsfknLTFQLESLEKENSQLDEENLElrrsVESLKCASMRMAQLQL 725
Cdd:PRK12705 95 AR-------AEKLDNLENQLEEREKA-------------LSARELELEELEKQLDNELYR----VAGLTPEQARKLLLKL 150
|
170
....*....|....*..
gi 1907079586 726 ENKELESEKEQLRKGLE 742
Cdd:PRK12705 151 LDAELEEEKAQRVKKIE 167
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
958-1226 |
5.78e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.21 E-value: 5.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 958 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRHElKTVKKNYEALKQRQDEermvqssipvsgeddkwgRESQEA 1037
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKRE------------------YEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1114
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1115 -----NSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270
....*....|....*....|....*....|....*..
gi 1907079586 1190 NLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
992-1201 |
5.89e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.05 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 992 QLRHELKTVKKNYEALKQ-RQDEERMVQSSIPVSG-EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Cdd:COG4913 239 RAHEALEDAREQIELLEPiRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1070 KQLETQNNNLQAQILALQRQTVslqeqnTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLliqqssleneNESIMKEREDL 1149
Cdd:COG4913 319 DALREELDELEAQIRGNGGDRL------EQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEF 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1907079586 1150 KSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:COG4913 383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-829 |
6.14e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 706 LRRSVESLKCASMR-MAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL---QKEENLDR 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1907079586 785 ELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQEtsQLEK 829
Cdd:PRK12704 101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE--QLQE 143
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
6.41e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 6.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907079586 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINvykescVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD------EELAELEAELEELEAE 164
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
535-846 |
6.84e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.10 E-value: 6.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 535 KAQLEKTIETLRENSERQIKiLEQENEHLNQTVSS-----------------LRQRSQISAE-ARVKDIEKENKILHESI 596
Cdd:PRK04863 792 RAEREELAERYATLSFDVQK-LQRLHQAFSRFIGShlavafeadpeaelrqlNRRRVELERAlADHESQEQQQRSQLEQA 870
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 597 KETCGKLSKIE-----FEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:PRK04863 871 KEGLSALNRLLprlnlLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT 950
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 672 NRKFKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrsVESLKcasmrmAQLqlenKELESEKEQLRKGLELMRASFkk 750
Cdd:PRK04863 951 QRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQAQAQL-- 1015
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 751 TERLEVsYQGLDTENQRLQKALensnkkiQQLESELQDL------EMENQTLQKSLE---ELKISSKRLEQLEKENKSLE 821
Cdd:PRK04863 1016 AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERARARRDElhaRLSANRSRRNQLEKQLTFCE 1087
|
330 340
....*....|....*....|....*
gi 1907079586 822 QETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1088 AEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
7.31e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.77 E-value: 7.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 305 ARMYRDELDALREKAVR--VDKLESELSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRT-----SELAEAPQK--SLGHE 453
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARytpnhPDVIALRAQiaALRAQ 306
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907079586 454 VNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN 512
Cdd:COG3206 307 LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1056-1137 |
7.66e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 40.22 E-value: 7.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1128
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 1907079586 1129 LIQQS--SLEN 1137
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
243-331 |
8.32e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 8.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARM-YRDELDALREKAVR 321
Cdd:COG4942 145 APARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEE 224
|
90
....*....|
gi 1907079586 322 VDKLESELSR 331
Cdd:COG4942 225 LEALIARLEA 234
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
453-590 |
8.49e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.15 E-value: 8.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 453 EVNELTSSKLLKLEMENQSLTKTVE-ELRStadsaagstsKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDL 531
Cdd:PRK12704 50 EAEAIKKEALLEAKEEIHKLRNEFEkELRE----------RRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKEL 119
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 532 MKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSSLRQRSQISAEARVKDIEKENK 590
Cdd:PRK12704 120 EQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEKVEEEARHEAAVLIKEIEEEAK 183
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
704-1222 |
8.55e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 8.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 704 LELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTErlevsYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:COG4913 245 EDAREQIELLE----PIRELAERYAAARERLAELEYLRAALRLWFAQRR-----LELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 784 SELQDLEMENQTLQKS--------LEELKissKRLEQLEKENKSLEQETSQLEKDKKQL-------EKENKRLRQQAEIK 848
Cdd:COG4913 316 ARLDALREELDELEAQirgnggdrLEQLE---REIERLERELEERERRRARLEALLAALglplpasAEEFAALRAEAAAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 849 DTTLEEnnvkigNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRA-TIDiKTLVTLREDLVSE-KLKTQQMN---- 922
Cdd:COG4913 393 LEALEE------ELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsNIP-ARLLALRDALAEAlGLDEAELPfvge 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 923 ------------------------------NDLEKLTHELEKIGLnKERLLHDEQSTDDSRYKLLESKLESTLKKsLEIK 972
Cdd:COG4913 466 lievrpeeerwrgaiervlggfaltllvppEHYAAALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGK-LDFK 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 973 EEKIAA-LEARLEESTNY-----NQQLRHELK------TVKKNYEAL-KQRQDEERmvqsSIPVSGEDdkwgresqeaTR 1039
Cdd:COG4913 544 PHPFRAwLEAELGRRFDYvcvdsPEELRRHPRaitragQVKGNGTRHeKDDRRRIR----SRYVLGFD----------NR 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1040 ELLKVKDRLIevernnATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNaklqvenstlnsqst 1119
Cdd:COG4913 610 AKLAALEAEL------AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--------------- 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 1120 slmnqnaqlliQQSSLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLE 1199
Cdd:COG4913 669 -----------EIAELEAELERLDASSDDLAALEEQL----EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733
|
570 580
....*....|....*....|....*
gi 1907079586 1200 DRYNQL--LKQKGQLEDLEKMIKTE 1222
Cdd:COG4913 734 DRLEAAedLARLELRALLEERFAAA 758
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
761-887 |
8.84e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 40.43 E-value: 8.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 761 LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE--- 837
Cdd:pfam05911 672 VSGSNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkc 748
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1907079586 838 ----NKRLRQQAEIKDTTLEENNVKIGNLEKEnktLFKEINVYKESCVRLKELE 887
Cdd:pfam05911 749 maesYEDLETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQ 799
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-982 |
9.11e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 9.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETCGKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 626 RAEELENELNHLGKENELLQkkitnlkitcEKLETLEQENSELERENrkFKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 706 LRRSVESLKcasmRMAQLQLENKELESEKEQLR----------KGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 776 NKKIQQLESELQDLEMENQTLQKSLEELKISskrleqlEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDttleen 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLP-------PDLSPEELLELLDRIEELQELLREAEELEEELQLEE------ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 856 nvkignLEKENKTLFKEINVYKE----SCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHE 931
Cdd:COG4717 368 ------LEQEIAALLAEAGVEDEeelrAALEQAEEYQELKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1907079586 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEAR 982
Cdd:COG4717 441 LEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-867 |
9.15e-03 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 37.76 E-value: 9.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907079586 777 KKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|.
gi 1907079586 857 VKIGNLEKENK 867
Cdd:pfam04871 81 LLLGDLEEKVE 91
|
|
| |
