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Conserved domains on  [gi|1907074237|ref|XP_036011608|]
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excitatory amino acid transporter 4 isoform X3 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301    76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301   136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301   166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301   244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301   324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
                         490
                  ....*....|....
gi 1907074237 530 EHlSQRELELQEAE 543
Cdd:COG1301   391 AK-WEGELDREKLN 403
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301    76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301   136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301   166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301   244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301   324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
                         490
                  ....*....|....
gi 1907074237 530 EHlSQRELELQEAE 543
Cdd:COG1301   391 AK-WEGELDREKLN 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-532 2.63e-110

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 334.88  E-value: 2.63e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISL 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907074237 454 ssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 532
Cdd:pfam00375 323 -------------TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
60-529 2.28e-38

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 146.35  E-value: 2.28e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027   13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027   87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027  118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027  184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISLSS 455
Cdd:PRK13027  258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907074237 456 RIpdslpvcsitataASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:PRK13027  337 LV-------------TSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301    76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301   136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301   166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301   244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301   324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
                         490
                  ....*....|....
gi 1907074237 530 EHlSQRELELQEAE 543
Cdd:COG1301   391 AK-WEGELDREKLN 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-532 2.63e-110

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 334.88  E-value: 2.63e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISL 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907074237 454 ssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 532
Cdd:pfam00375 323 -------------TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
60-529 2.28e-38

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 146.35  E-value: 2.28e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027   13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027   87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027  118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027  184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISLSS 455
Cdd:PRK13027  258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907074237 456 RIpdslpvcsitataASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:PRK13027  337 LV-------------TSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
60-545 2.25e-35

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 137.73  E-value: 2.25e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  60 VSAVIIGV-------SLAFALRPYqlsyrqikyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVY 131
Cdd:PRK01663   14 LVAIIIGIllghfypELGAQMKPL-------------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 132 YMVTTVIAVFIGILMVTIIHPGKGskeglhregrietvptadafmdlvRNMFPPNLVEACFKQFktqystrvvtrtivrT 211
Cdd:PRK01663   81 FEIVSTIALIIGLIVVNVVQPGAG------------------------MNIDPATLDAKAVAQY---------------A 121
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 212 DNGSELGAsmsptssvenetsilenvtraLGTLQEVISfeeTVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRD 291
Cdd:PRK01663  122 AQAHEQGT---------------------VDFLMDIIP---TTVVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFD 176
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 292 FFDSLNEAIMRLVGIIIWYAPVGILFLIAGKI--LEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFlvthrNPFP 369
Cdd:PRK01663  177 FIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIgkYGVGSLVQLGQLIGCFYITCILFVFVVLGAIARLTGF-----SIFK 251
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:PRK01663  252 FIRYIKEELLIVLGTSSSESALPRMMEKMEK-LGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQI 330
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 450 TIslssripdsLPVCSITataaSVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAV 528
Cdd:PRK01663  331 TL---------LAVLLLT----SKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVV 397
                         490
                  ....*....|....*..
gi 1907074237 529 IehlSQRELELQEAELT 545
Cdd:PRK01663  398 V---AKWEKELDREKLD 411
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
62-529 5.92e-35

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 136.82  E-value: 5.92e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  62 AVIIGVSLAFALRpYQLSYRQ---IKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTV 137
Cdd:PRK11283   15 ALVLGILLGAYLH-YHSDSRDwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITT 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 138 IAVFIGILMVTIIHPGKGSKEGL--------HREGRIETVPTADAFMDLVRNMFPPNLVeacfkqfktqystrvvtrtiv 209
Cdd:PRK11283   94 VAIILGITLANVFQPGAGIDMSQlatvdiskYQSTTEEVQSHSHGLMGTILSLIPTNIF--------------------- 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 210 rtdngselgASMsptssvenetsilenvtrALGtlqevisfeETVPVpgsanginalglVVFSVAFGLVIGGMKHKGRV- 288
Cdd:PRK11283  153 ---------ASM------------------AKG---------EMLPI------------IFFSVLFGLGLSSLPATHREp 184
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 289 LRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLggQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRnPF 368
Cdd:PRK11283  185 LVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALVVLGIVARLCGLS-IW 261
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 369 PFIGGMLQALITAMGTSSSSATLPitfRCLE--EGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLG 446
Cdd:PRK11283  262 ILIRILKDELILAYSTASSETVLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 447 QITTISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGA 526
Cdd:PRK11283  339 QEIILVL-------------TLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405

                  ...
gi 1907074237 527 AVI 529
Cdd:PRK11283  406 LVI 408
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
260-478 9.64e-17

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 82.60  E-value: 9.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:PRK13628  136 DNPINALlnanyiGILAWAIGLGL---ALRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAG 212
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:PRK13628  213 yAQL----LAVLVGcMLFVALVVNPLIVFWKIRRNPYPLV---FTCLresgVTAFFTRSSAANIPVNMA-LCEKLGLDED 284
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907074237 408 ITRFVLPVGATVNMDGtalyealAAIFIAQvnnyeLNLGQITTISLSSRIPDSLpVCSITATAASVGAAGI 478
Cdd:PRK13628  285 TYSVSIPLGATINMAG-------AAITITV-----LTLAAVHTLGIPVDLPTAL-LLSVVAAISACGASGV 342
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
61-529 9.96e-17

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 82.95  E-value: 9.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237  61 SAVIIGVSLAFALrpyQLSY--------RQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDN-KATGRMGMRAAVY 131
Cdd:COG1823    36 TGLGLGILFGLIL---QLIYgagspvikQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLKNaSSLGKISGLIIGI 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 132 YMVTTVIAVFIGILMVTIIhpgkgskeGLhregrietvpTADAFMDLVRNmfppnlveacfkqfktqystrvvtrtivrT 211
Cdd:COG1823   113 LLGTTAIAALVGILVALLF--------GL----------TAEGLTQGAAE-----------------------------T 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 212 DNGSELgasmsptssvENETSILENVTRAlgtlQEVISFEETVP---VPGsANGINALGLVVFSVAFGLVIGGMKHK--- 285
Cdd:COG1823   146 ARGEAL----------EERLGEVEDLSLP----QQILSFIPTNPfadLTG-ARPTSTIAVVIFAAFLGIAALGLRRKkpe 210
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 286 -GRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAgKIL---EMEDMAVLGG-----QLGMYTLTVIVGLFLHAGGVLP 356
Cdd:COG1823   211 qAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVatsDFADILNLGKfvvasYVALIIMFIVHLLLLALAGLNP 289
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 357 LIYFlvthRNPFPfiggmlqALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTA-LYEALAAIFI 435
Cdd:COG1823   290 LTYF----KKVWP-------VLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMI 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 436 AQ---VNNYE----LNLGQITTISlssripdslpvcsitataaSVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDW 508
Cdd:COG1823   359 APtvgINPLDpsfiLTLIAVVTIS-------------------SFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEP 419
                         490       500
                  ....*....|....*....|.
gi 1907074237 509 FLDRLRTMTNVlGDSIGAAVI 529
Cdd:COG1823   420 LIDMGRTALNV-SGSMTAGTV 439
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
260-479 6.09e-16

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 79.83  E-value: 6.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:COG3633   135 DNPVNALananyiGILAWAIGLGL---ALRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATTGFSALLG 211
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:COG3633   212 yAHL----LAVLVGcMLFVALVVNPLIVFLKIRRNPYPLV---FTCLresgITAFFTRSSAANIPVNMA-LCEKLGLDED 283
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907074237 408 ITRFVLPVGATVNMDGtalyealAAIFIAQvnnyeLNLGQITTISLSSRIPDSLpVCSITATAASVGAAGIP 479
Cdd:COG3633   284 TYSVSIPLGATINMAG-------AAITITV-----LTLAAVHTLGIEVDLPTAL-LLSVVAAVSACGASGVA 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
264-536 4.70e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 61.22  E-value: 4.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 264 NALGLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVlgGQLGMYTLTV 343
Cdd:PRK14695   60 NYIGILSWAVIFGI---AMREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSL--ANYGILLVLL 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 344 IVGLFLHAGGVLPLIYFLVTHRNPFPFIGGMLQ-ALITAMGTSSSSATLPITFRcLEEGLGVDRRITRFVLPVGATVNMD 422
Cdd:PRK14695  135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMA 213
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907074237 423 GTALyeALAAIFIAQVNNYELNLGQITTIslssripdslpVCSITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITL 502
Cdd:PRK14695  214 GVAI--TINLLTLVTVNTLGIPVDFATAF-----------VLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQ 280
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1907074237 503 IIAVDWFL----DRLRTMTNVLGDSIGAAVIEHLSQRE 536
Cdd:PRK14695  281 IVGVGFVIgviqDSCETALNSSTDVLFTAVAEYAATRK 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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